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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094663
log Bayes Factor = 67.2321
Chromosome 6   position 31,107,087  (GRCh37) Explore rs3094663 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E11.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
E78.0 Pure hypercholesterolaemia
0.000 0.002 0.998
G35 Multiple sclerosis
0.998 0.002 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.006 0.994
E70-E90 Metabolic disorders
0.000 0.010 0.990
E14 Unspecified diabetes mellitus
0.000 0.010 0.990
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.019 0.981
E16 Other disorders of pancreatic internal secretion
0.000 0.032 0.967
E16.2 Hypoglycaemia, unspecified
0.000 0.049 0.951
E10.3 With ophthalmic complications
0.000 0.050 0.950
C83.3 Large cell (diffuse)
0.000 0.065 0.935
E14.3 With ophthalmic complications
0.000 0.075 0.925
E14.9 Without complications
0.000 0.079 0.921
E11.0 With coma
0.000 0.111 0.889
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.123 0.876
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.131 0.869
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.132 0.868
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.132 0.868
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.134 0.866
L40.9 Psoriasis, unspecified
0.000 0.144 0.856
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.145 0.855
E10.1 With ketoacidosis
0.000 0.146 0.854
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.151 0.849
C85.1 B-cell lymphoma, unspecified
0.000 0.151 0.849
E11.1 With ketoacidosis
0.000 0.171 0.829
E83 Disorders of mineral metabolism
0.813 0.174 0.013
E40-E46 Malnutrition
0.000 0.175 0.825
E78.2 Mixed hyperlipidaemia
0.000 0.176 0.824
E07 Other disorders of thyroid
0.000 0.193 0.807
E14.5 With peripheral circulatory complications
0.000 0.197 0.803
E10.8 With unspecified complications
0.000 0.199 0.801
E10.6 With other specified complications
0.000 0.203 0.797
E74 Other disorders of carbohydrate metabolism
0.000 0.210 0.790
E78.4 Other hyperlipidaemia
0.000 0.215 0.785
E13 Other specified diabetes mellitus
0.000 0.215 0.785
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.221 0.779
E78.5 Hyperlipidaemia, unspecified
0.000 0.225 0.775
E79 Disorders of purine and pyrimidine metabolism
0.000 0.227 0.773
E14.4 With neurological complications
0.000 0.227 0.773
E14.1 With ketoacidosis
0.000 0.232 0.768
E10.0 With coma
0.000 0.240 0.760
E16.1 Other hypoglycaemia
0.000 0.241 0.759
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.248 0.752
G35-G37 Demyelinating diseases of the central nervous system
0.748 0.252 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.252 0.748
E14.6 With other specified complications
0.000 0.260 0.740
E78.8 Other disorders of lipoprotein metabolism
0.000 0.263 0.737
E83.3 Disorders of phosphorus metabolism
0.731 0.266 0.003
E11.2 With renal complications
0.000 0.270 0.730
E78.6 Lipoprotein deficiency
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E77 Disorders of glycoprotein metabolism
0.000 0.290 0.710
E76 Disorders of glycosaminoglycan metabolism
0.000 0.290 0.710
E72 Other disorders of amino-acid metabolism
0.000 0.290 0.710
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.290 0.710
E70 Disorders of aromatic amino-acid metabolism
0.000 0.290 0.710
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.290 0.710
E14.7 With multiple complications
0.000 0.290 0.710
E14.0 With coma
0.000 0.290 0.710
C82.2 Large cell, follicular
0.000 0.292 0.708
E11.8 With unspecified complications
0.000 0.292 0.708
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.295 0.705
E03.8 Other specified hypothyroidism
0.000 0.295 0.704
E15 Nondiabetic hypoglycaemic coma
0.000 0.297 0.703
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.297 0.703
E84 Cystic fibrosis
0.000 0.301 0.699
E46 Unspecified protein-energy malnutrition
0.000 0.301 0.699
E14.2 Withrenal complications
0.000 0.304 0.696
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.306 0.694
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.306 0.694
E16.4 Abnormal secretion of gastrin
0.000 0.306 0.694
E16.3 Increased secretion of glucagon
0.000 0.306 0.694
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.309 0.691
G37 Other demyelinating diseases of central nervous system
0.690 0.310 0.000
K90 Intestinal malabsorption
0.000 0.316 0.684
C83.7 Burkitt's tumour
0.000 0.317 0.683
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.326 0.674
C82.3 Follicular lymphoma grade IIIa
0.000 0.327 0.673
E14.8 With unspecified complications
0.000 0.330 0.670
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.331 0.669
E83.9 Disorder of mineral metabolism, unspecified
0.661 0.331 0.008
E11.5 With peripheral circulatory complications
0.000 0.337 0.663
E88 Other metabolic disorders
0.000 0.351 0.649
C82.0 Small cleaved cell, follicular
0.000 0.355 0.645
E07.9 Disorder of thyroid, unspecified
0.000 0.356 0.644
G37.9 Demyelinating disease of central nervous system, unspecified
0.643 0.357 0.000
E13.9 Without complications
0.000 0.359 0.641
C86 Other specified types of T/NK-cell lymphoma
0.000 0.359 0.640
E10.5 With peripheral circulatory complications
0.000 0.364 0.635
C83.6 Undifferentiated (diffuse)
0.000 0.371 0.628
C83.5 Lymphoblastic (diffuse)
0.000 0.371 0.628
C83.4 Immunoblastic (diffuse)
0.000 0.371 0.628
C83.2 Mixed small and large cell (diffuse)
0.000 0.371 0.628
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.377 0.623
E03.1 Congenital hypothyroidism without goitre
0.000 0.377 0.623
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.377 0.623
C85.0 Lymphosarcoma
0.000 0.377 0.623
C82.6 Cutaneous follicle centre lymphoma
0.000 0.378 0.622
C82.5 Diffuse follicle centre lymphoma
0.000 0.378 0.622
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.382 0.618
E78.3 Hyperchylomicronaemia
0.000 0.383 0.617
E07.8 Other specified disorders of thyroid
0.000 0.388 0.612
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.392 0.607
E80.6 Other disorders of bilirubin metabolism
0.000 0.405 0.595
E10.4 With neurological complications
0.000 0.406 0.594
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.408 0.592
E83.8 Other disorders of mineral metabolism
0.583 0.408 0.010
E83.2 Disorders of zinc metabolism
0.583 0.408 0.010
E83.0 Disorders of copper metabolism
0.583 0.408 0.010
E80.2 Other porphyria
0.000 0.408 0.592
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.408 0.591
E45 Retarded development following protein-energy malnutrition
0.000 0.408 0.591
E43 Unspecified severe protein-energy malnutrition
0.000 0.408 0.591
E42 Marasmic kwashiorkor
0.000 0.408 0.591
E41 Nutritional marasmus
0.000 0.408 0.591
E40 Kwashiorkor
0.000 0.408 0.591
E07.1 Dyshormogenetic goitre
0.000 0.422 0.578
E07.0 Hypersecretion of calcitonin
0.000 0.422 0.578
C94 Other leukaemias of specified cell type
0.000 0.424 0.575
E05.8 Other thyrotoxicosis
0.000 0.425 0.575
E80.1 Porphyria cutanea tarda
0.000 0.431 0.569
C82.4 Follicular lymphoma grade IIIb
0.000 0.433 0.567
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.433 0.566
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.433 0.566
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.433 0.566
E74.2 Disorders of galactose metabolism
0.000 0.433 0.566
E74.1 Disorders of fructose metabolism
0.000 0.433 0.566
I25.1 Atherosclerotic heart disease
0.000 0.434 0.566
C84.0 Mycosis fungoides
0.000 0.435 0.565
I25 Chronic ischaemic heart disease
0.000 0.435 0.565
E10.2 With renal complications
0.000 0.437 0.563
E13.8 With unspecified complications
0.000 0.437 0.563
E13.7 With multiple complications
0.000 0.437 0.563
E13.6 With other specified complications
0.000 0.437 0.563
E13.5 With peripheral circulatory complications
0.000 0.437 0.563
E13.4 With neurological complications
0.000 0.437 0.563
E13.2 With renal complications
0.000 0.437 0.563
E13.1 With ketoacidosis
0.000 0.437 0.563
E13.0 With coma
0.000 0.437 0.563
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.438 0.562
G36 Other acute disseminated demyelination
0.562 0.438 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.441 0.559
E80.5 Crigler-Najjar syndrome
0.000 0.441 0.559
E80.3 Defects of catalase and peroxydase
0.000 0.441 0.559
E80.0 Hereditary erythropoietic porphyria
0.000 0.441 0.559
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.443 0.557
E80.4 Gilbert's syndrome
0.000 0.443 0.557
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.445 0.554
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.445 0.554
E79.1 Lesch-Nyhan syndrome
0.000 0.445 0.554
E13.3 With ophthalmic complications
0.000 0.451 0.548
G37.8 Other specified demyelinating diseases of central nervous system
0.548 0.452 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.452 0.548
I25.5 Ischaemic cardiomyopathy
0.000 0.469 0.531
C93 Monocytic leukaemia
0.000 0.469 0.530
E83.4 Disorders of magnesium metabolism
0.521 0.475 0.004
C84.4 Peripheral T-cell lymphoma
0.000 0.475 0.525
I25.2 Old myocardial infarction
0.000 0.478 0.522
E73 Lactose intolerance
0.001 0.479 0.521
C84.5 Other and unspecified T-cell lymphomas
0.000 0.482 0.518
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E74.0 Glycogen storage disease
0.000 0.486 0.514
C83.1 Small cleaved cell (diffuse)
0.000 0.488 0.511
C88 Malignant immunoproliferative diseases
0.001 0.489 0.511
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.491 0.509
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.491 0.509
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.491 0.509
E70.3 Albinism
0.000 0.491 0.509
E70.2 Disorders of tyrosine metabolism
0.000 0.491 0.509
E70.1 Other hyperphenylalaninaemias
0.000 0.491 0.509
E70.0 Classical phenylketonuria
0.000 0.491 0.509
E71.3 Disorders of fatty-acid metabolism
0.000 0.491 0.509
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.491 0.509
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.491 0.509
E71.0 Maple-syrup-urine disease
0.000 0.491 0.509
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.491 0.509
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.491 0.509
E72.5 Disorders of glycine metabolism
0.000 0.491 0.509
E72.4 Disorders of ornithine metabolism
0.000 0.491 0.509
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.491 0.509
E72.2 Disorders of urea cycle metabolism
0.000 0.491 0.509
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.491 0.509
E72.0 Disorders of amino-acid transport
0.000 0.491 0.509
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.491 0.509
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.491 0.509
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.491 0.509
E76.2 Other mucopolysaccharidoses
0.000 0.491 0.509
E76.1 Mucopolysaccharidosis, type II
0.000 0.491 0.509
E76.0 Mucopolysaccharidosis, type I
0.000 0.491 0.509
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.491 0.509
E77.8 Other disorders of glycoprotein metabolism
0.000 0.491 0.509
E77.1 Defects in glycoprotein degradation
0.000 0.491 0.509
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.491 0.509
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.495 0.505
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.495 0.505
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.495 0.505
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.495 0.505
C84.3 Lymphoepithelioid lymphoma
0.000 0.495 0.505
C84.2 T-zone lymphoma
0.000 0.495 0.505
C84.1 Sezary's diease
0.000 0.495 0.505
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.496 0.504
E88.8 Other specified metabolic disorders
0.000 0.498 0.502
E84.8 Cystic fibrosis with other manifestations
0.000 0.498 0.501
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.498 0.501
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.498 0.501
E88.2 Lipomatosis, not elsewhere classified
0.000 0.500 0.500
G37.5 Concentric sclerosis [Balo]
0.495 0.505 0.000
G37.4 Subacute necrotising myelitis
0.495 0.505 0.000
G37.2 Central pontine myelinolysis
0.495 0.505 0.000
G37.1 Central demyelination of corpus callosum
0.495 0.505 0.000
G37.0 Diffuse sclerosis
0.495 0.505 0.000
C81 Hodgkin's disease
0.000 0.507 0.492
E84.9 Cystic fibrosis, unspecified
0.000 0.509 0.491
K90.3 Pancreatic steatorrhoea
0.000 0.510 0.490
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.510 0.490
K90.1 Tropical sprue
0.000 0.510 0.490
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.513 0.487
E75.6 Lipid storage disorder, unspecified
0.000 0.520 0.479
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.520 0.479
E75.3 Sphingolipidosis, unspecified
0.000 0.520 0.479
E75.2 Other sphingolipidosis
0.000 0.520 0.479
E75.1 Other gangliosidosis
0.000 0.520 0.479
E75.0 GM2 gangliosidosis
0.000 0.520 0.479
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.523 0.477
E11.6 With other specified complications
0.000 0.523 0.476
K90.8 Other intestinal malabsorption
0.000 0.524 0.476
E88.3 Tumour lysis syndrome
0.000 0.525 0.474
E11.4 With neurological complications
0.000 0.531 0.469
I20-I25 Ischaemic heart diseases
0.000 0.533 0.467
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.534 0.465
E88.9 Metabolic disorder, unspecified
0.000 0.535 0.465
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.540 0.459
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.541 0.459
C86.4 Blastic NK-cell lymphoma
0.000 0.541 0.459
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.541 0.459
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.541 0.459
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.541 0.459
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.541 0.459
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.545 0.455
I22 Subsequent myocardial infarction
0.000 0.547 0.453
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.452 0.548 0.000
L40 Psoriasis
0.000 0.548 0.452
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.552 0.448
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.553 0.447
C96.8 Histiocytic sarcoma
0.000 0.553 0.447
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.553 0.447
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.553 0.447
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.553 0.447
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.553 0.447
C96.3 True histiocytic lymphoma
0.000 0.553 0.447
C96.2 Malignant mast cell tumour
0.000 0.553 0.447
C96.1 Malignant histiocytosis
0.000 0.553 0.447
C96.0 Letterer-Siwe disease
0.000 0.553 0.447
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.554 0.446
E75.5 Other lipid storage disorders
0.000 0.562 0.438
C83.0 Small cell (diffuse)
0.000 0.568 0.432
E11.3 With ophthalmic complications
0.000 0.568 0.432
G36.0 Neuromyelitis optica [Devic]
0.429 0.571 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.576 0.424
E44.0 Moderate protein-energy malnutrition
0.000 0.576 0.424
E89.4 Postprocedural ovarian failure
0.000 0.577 0.422
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.585 0.415
C94.7 Other specified leukaemias
0.000 0.587 0.412
C94.5 Acute myelofibrosis
0.000 0.587 0.412
C94.4 Acute panmyelosis
0.000 0.587 0.412
C94.3 Mast cell leukaemia
0.000 0.587 0.412
C94.2 Acute megakaryoblastic leukaemia
0.000 0.587 0.412
C94.1 Chronic erythraemia
0.000 0.587 0.412
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.587 0.412
I25.6 Silent myocardial ischaemia
0.000 0.595 0.405
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.596 0.404
E06 Thyroiditis
0.000 0.597 0.403
E85 Amyloidosis
0.001 0.597 0.403
E83.5 Disorders of calcium metabolism
0.402 0.597 0.001
G36.9 Acute disseminated demyelination, unspecified
0.403 0.597 0.000
G36.8 Other specified acute disseminated demyelination
0.403 0.597 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.403 0.597 0.000
C95 Leukaemia of unspecified cell type
0.001 0.597 0.402
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.598 0.402
M06.9 Rheumatoid arthritis, unspecified
0.000 0.598 0.402
E89.3 Postprocedural hypopituitarism
0.000 0.600 0.400
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.600 0.400
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.600 0.400
E89.5 Postprocedural testicular hypofunction
0.000 0.600 0.400
E89.1 Postprocedural hypoinsulinaemia
0.000 0.600 0.400
C91 Lymphoid leukaemia
0.001 0.607 0.393
C93.9 Monocytic leukaemia, unspecified
0.000 0.619 0.380
C93.7 Other monocytic leukaemia
0.000 0.619 0.380
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.619 0.380
C93.2 Subacute monocytic leukaemia
0.000 0.619 0.380
C93.0 Acute monocytic leukaemia
0.000 0.619 0.380
E73.8 Other lactose intolerance
0.001 0.626 0.373
E73.1 Secondary lactase deficiency
0.001 0.626 0.373
E73.0 Congenital lactase deficiency
0.001 0.626 0.373
I23 Certain current complications following acute myocardial infarction
0.000 0.630 0.370
I20 Angina pectoris
0.000 0.630 0.370
I25.4 Coronary artery aneurysm
0.000 0.631 0.369
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.631 0.369
C88.9 Malignant immunoproliferative disease, unspecified
0.001 0.633 0.366
C88.7 Other malignant immunoproliferative diseases
0.001 0.633 0.366
C88.3 Immunoproliferative small intestinal disease
0.001 0.633 0.366
C88.2 Gamma heavy chain disease
0.001 0.633 0.366
C88.1 Alpha heavy chain disease
0.001 0.633 0.366
L40.8 Other psoriasis
0.000 0.633 0.367
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.001 0.635 0.365
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.635 0.365
I20.9 Angina pectoris, unspecified
0.000 0.636 0.364
E89.2 Postprocedural hypoparathyroidism
0.000 0.638 0.362
C81.0 Lymphocytic predominance
0.000 0.645 0.354
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.647 0.353
C81.3 Lymphocytic depletion
0.000 0.647 0.353
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.648 0.352
I24 Other acute ischaemic heart diseases
0.000 0.653 0.347
I22.8 Subsequent myocardial infarction of other sites
0.000 0.656 0.344
C81.7 Other Hodgkin's disease
0.000 0.656 0.344
E65-E68 Obesity and other hyperalimentation
0.000 0.657 0.343
C91.9 Lymphoid leukaemia, unspecified
0.000 0.657 0.343
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.660 0.340
C81.2 Mixed cellularity
0.000 0.661 0.339
C92 Myeloid leukaemia
0.000 0.664 0.336
L40.1 Generalised pustular psoriasis
0.000 0.669 0.331
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.670 0.330
L40.4 Guttate psoriasis
0.000 0.671 0.329
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.672 0.328
C81.9 Hodgkin's disease, unspecified
0.000 0.673 0.327
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.001 0.674 0.326
L40.2 Acrodermatitis continua
0.000 0.676 0.324
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.684 0.316
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.685 0.315
L40.0 Psoriasis vulgaris
0.000 0.692 0.307
I23.8 Other current complications following acute myocardial infarction
0.000 0.699 0.301
E06.5 Other chronic thyroiditis
0.000 0.700 0.299
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.701 0.299
C81.1 Nodular sclerosis
0.000 0.701 0.299
I25.3 Aneurysm of heart
0.000 0.704 0.296
E06.4 Drug-induced thyroiditis
0.000 0.711 0.289
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.711 0.289
E06.0 Acute thyroiditis
0.000 0.711 0.289
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.711 0.289
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.711 0.289
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.711 0.289
C95.7 Other leukaemia of unspecified cell type
0.001 0.711 0.288
C95.2 Subacute leukaemia of unspecified cell type
0.001 0.711 0.288
C93.1 Chronic monocytic leukaemia
0.001 0.712 0.288
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.716 0.284
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.717 0.282
C91.8 Mature B-cell leukaemia Burkitt-type
0.001 0.718 0.282
C91.7 Other lymphoid leukaemia
0.001 0.718 0.282
C91.6 Prolymphocytic leukaemia of T-cell type
0.001 0.718 0.282
C91.3 Prolymphocytic leukaemia
0.001 0.718 0.282
C91.2 Subacute lymphocytic leukaemia
0.001 0.718 0.282
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.718 0.282
L40.3 Pustulosis palmaris et plantaris
0.000 0.718 0.281
I20.1 Angina pectoris with documented spasm
0.000 0.725 0.275
C91.5 Adult T-cell leukaemia
0.001 0.729 0.270
E85.8 Other amyloidosis
0.001 0.731 0.268
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.734 0.265
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.734 0.265
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.734 0.265
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.734 0.265
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.734 0.265
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.734 0.265
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.734 0.265
L40.5 Arthropathic psoriasis
0.000 0.736 0.264
E20-E35 Disorders of other endocrine glands
0.000 0.738 0.262
E06.1 Subacute thyroiditis
0.000 0.743 0.256
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.748 0.252
C95.1 Chronic leukaemia of unspecified cell type
0.001 0.749 0.250
E85.4 Organ-limited amyloidosis
0.001 0.754 0.246
E67 Other hyperalimentation
0.000 0.754 0.246
E68 Sequelae of hyperalimentation
0.000 0.754 0.246
E85.9 Amyloidosis, unspecified
0.001 0.756 0.243
E28 Ovarian dysfunction
0.000 0.757 0.243
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.759 0.241
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.759 0.241
C92.5 Acute myelomonocytic leukaemia
0.000 0.759 0.241
C92.3 Myeloid sarcoma
0.000 0.759 0.241
C92.2 Subacute myeloid leukaemia
0.000 0.759 0.241
E50-E64 Other nutritional deficiencies
0.000 0.761 0.239
M06 Other rheumatoid arthritis
0.000 0.762 0.238
E28.2 Polycystic ovarian syndrome
0.000 0.763 0.237
L40-L45 Papulosquamous disorders
0.000 0.763 0.237
C92.7 Other myeloid leukaemia
0.000 0.763 0.236
C95.9 Leukaemia, unspecified
0.001 0.764 0.235
C92.9 Myeloid leukaemia, unspecified
0.000 0.764 0.235
C95.0 Acute leukaemia of unspecified cell type
0.001 0.768 0.231
C91.1 Chronic lymphocytic leukaemia
0.000 0.772 0.228
C92.4 Acute promyelocytic leukaemia
0.000 0.772 0.227
C92.1 Chronic myeloid leukaemia
0.000 0.780 0.220
C90 Multiple myeloma and malignant plasma cell neoplasms
0.032 0.781 0.186
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.781 0.218
E85.3 Secondary systemic amyloidosis
0.001 0.781 0.218
C91.0 Acute lymphoblastic leukaemia
0.001 0.785 0.214
M06.3 Rheumatoid nodule
0.000 0.788 0.212
E06.9 Thyroiditis, unspecified
0.001 0.798 0.201
E24 Cushing's syndrome
0.000 0.799 0.201
I24.1 Dressler's syndrome
0.000 0.800 0.199
E06.3 Autoimmune thyroiditis
0.000 0.803 0.196
E65 Localised adiposity
0.000 0.810 0.190
M06.4 Inflammatory polyarthropathy
0.000 0.810 0.190
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.812 0.188
E32 Diseases of thymus
0.000 0.812 0.188
E31 Polyglandular dysfunction
0.000 0.812 0.188
E30 Disorders of puberty, not elsewhere classified
0.000 0.812 0.188
E25 Adrenogenital disorders
0.000 0.812 0.188
L43 Lichen planus
0.000 0.812 0.188
I24.8 Other forms of acute ischaemic heart disease
0.000 0.814 0.186
E73.9 Lactose intolerance, unspecified
0.001 0.815 0.184
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.815 0.185
E26 Hyperaldosteronism
0.000 0.817 0.183
M06.34 Rheumatoid nodule (Hand)
0.000 0.817 0.183
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.821 0.179
L42 Pityriasis rosea
0.000 0.823 0.177
E67.8 Other specified hyperalimentation
0.000 0.823 0.176
E67.3 Hypervitaminosis D
0.000 0.823 0.176
E67.2 Megavitamin-B6 syndrome
0.000 0.823 0.176
E67.1 Hypercarotenaemia
0.000 0.823 0.176
E67.0 Hypervitaminosis A
0.000 0.823 0.176
E28.9 Ovarian dysfunction, unspecified
0.000 0.826 0.174
E28.8 Other ovarian dysfunction
0.000 0.826 0.174
E28.1 Androgen excess
0.000 0.826 0.174
E28.0 Oestrogen excess
0.000 0.826 0.174
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.828 0.171
E63 Other nutritional deficiencies
0.000 0.828 0.171
E50 Vitamin A deficiency
0.000 0.828 0.171
E60 Dietary zinc deficiency
0.000 0.828 0.171
E59 Dietary selenium deficiency
0.000 0.828 0.171
E54 Ascorbic acid deficiency
0.000 0.828 0.171
E52 Niacin deficiency [pellagra]
0.000 0.828 0.171
E56 Other vitamin deficiencies
0.000 0.829 0.171
M06.2 Rheumatoid bursitis
0.000 0.829 0.170
M06.1 Adult-onset Still's disease
0.000 0.829 0.170
L44 Other papulosquamous disorders
0.000 0.830 0.170
L41 Parapsoriasis
0.000 0.830 0.170
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.830 0.170
C88.0 Waldenstrom's macroglobulinaemia
0.002 0.834 0.164
M06.8 Other specified rheumatoid arthritis
0.000 0.835 0.165
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.838 0.162
L43.9 Lichen planus, unspecified
0.000 0.838 0.162
E51 Thiamine deficiency
0.000 0.840 0.159
E24.9 Cushing's syndrome, unspecified
0.000 0.843 0.157
E58 Dietary calcium deficiency
0.000 0.843 0.156
E20 Hypoparathyroidism
0.000 0.844 0.156
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.844 0.156
E23 Hypofunction and other disorders of pituitary gland
0.000 0.844 0.156
C90.3 Solitary plasmacytoma
0.023 0.846 0.131
C90.1 Plasma cell leukaemia
0.023 0.846 0.131
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.848 0.152
M06.38 Rheumatoid nodule (Other)
0.000 0.848 0.152
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.848 0.152
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.848 0.152
M06.33 Rheumatoid nodule (Forearm)
0.000 0.848 0.152
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.848 0.152
E21.3 Hyperparathyroidism, unspecified
0.000 0.849 0.151
E61 Deficiency of other nutrient elements
0.000 0.850 0.150
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.851 0.149
E29 Testicular dysfunction
0.000 0.854 0.146
E24.2 Drug-induced Cushing's syndrome
0.000 0.854 0.145
E24.8 Other Cushing's syndrome
0.000 0.855 0.144

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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