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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094738
log Bayes Factor = 40.0205
Chromosome 6   position 31,407,913  (GRCh37) Explore rs3094738 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E11.9 Without complications
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
L40 Psoriasis
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
J45.9 Asthma, unspecified
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.003 0.997
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
L40.5 Arthropathic psoriasis
0.000 0.006 0.994
K90.0 Coeliac disease
0.000 0.010 0.990
G00-G09 Inflammatory diseases of the central nervous system
0.975 0.025 0.000
G30-G32 Other degenerative diseases of the nervous system
0.969 0.031 0.000
G20-G26 Extrapyramidal and movement disorders
0.968 0.032 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.952 0.048 0.000
G20 Parkinson's disease
0.949 0.051 0.000
E83 Disorders of mineral metabolism
0.944 0.056 0.001
G31.9 Degenerative disease of nervous system, unspecified
0.939 0.061 0.000
E83.5 Disorders of calcium metabolism
0.919 0.081 0.000
E10.1 With ketoacidosis
0.000 0.082 0.918
E14 Unspecified diabetes mellitus
0.000 0.097 0.903
G37 Other demyelinating diseases of central nervous system
0.891 0.109 0.000
G03 Meningitis due to other and unspecified causes
0.881 0.119 0.000
E10.4 With neurological complications
0.000 0.119 0.881
L40-L45 Papulosquamous disorders
0.000 0.126 0.874
G31.2 Degeneration of nervous system due to alcohol
0.854 0.146 0.000
L43 Lichen planus
0.000 0.151 0.848
G90-G99 Other disorders of the nervous system
0.843 0.157 0.000
E83.3 Disorders of phosphorus metabolism
0.836 0.164 0.000
E11.5 With peripheral circulatory complications
0.000 0.167 0.833
L43.9 Lichen planus, unspecified
0.000 0.169 0.831
E10.2 With renal complications
0.000 0.169 0.831
E13 Other specified diabetes mellitus
0.000 0.173 0.826
G00 Bacterial meningitis, not elsewhere classified
0.819 0.181 0.000
G03.9 Meningitis, unspecified
0.814 0.186 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.805 0.195 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.803 0.197 0.000
E14.9 Without complications
0.000 0.206 0.794
G80-G83 Cerebral palsy and other paralytic syndromes
0.792 0.208 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.790 0.210 0.000
L40.0 Psoriasis vulgaris
0.000 0.211 0.789
G93 Other disorders of brain
0.783 0.217 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.776 0.224 0.000
E10.5 With peripheral circulatory complications
0.000 0.226 0.774
E14.3 With ophthalmic complications
0.000 0.236 0.764
G06 Intracranial and intraspinal abscess and granuloma
0.761 0.239 0.000
G96 Other disorders of central nervous system
0.759 0.241 0.000
E11.6 With other specified complications
0.000 0.245 0.755
G37.8 Other specified demyelinating diseases of central nervous system
0.750 0.250 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.749 0.250 0.000
E11.0 With coma
0.000 0.268 0.732
E11.1 With ketoacidosis
0.000 0.278 0.722
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
L40.8 Other psoriasis
0.000 0.284 0.716
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.3 Pustulosis palmaris et plantaris
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L40.1 Generalised pustular psoriasis
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.000
G25 Other extrapyramidal and movement disorders
0.712 0.288 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.706 0.294 0.000
G93.4 Encephalopathy, unspecified
0.706 0.294 0.000
E13.9 Without complications
0.000 0.297 0.702
G96.0 Cerebrospinal fluid leak
0.701 0.299 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.699 0.301 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.699 0.301 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.694 0.305 0.000
G23 Other degenerative diseases of basal ganglia
0.694 0.306 0.000
G21 Secondary Parkinsonism
0.694 0.306 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.694 0.306 0.000
G22 Parkinsonism in diseases classified elsewhere
0.694 0.306 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.682 0.317 0.000
G93.3 Postviral fatigue syndrome
0.680 0.320 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.676 0.323 0.001
E83.8 Other disorders of mineral metabolism
0.676 0.323 0.001
E83.2 Disorders of zinc metabolism
0.676 0.323 0.001
E83.0 Disorders of copper metabolism
0.676 0.323 0.001
G24 Dystonia
0.676 0.324 0.000
G93.8 Other specified disorders of brain
0.673 0.327 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.672 0.328 0.000
G83 Other paralytic syndromes
0.668 0.332 0.000
G30 Alzheimer's disease
0.667 0.333 0.000
G00.9 Bacterial meningitis, unspecified
0.663 0.337 0.000
E11.8 With unspecified complications
0.000 0.338 0.662
G00.1 Pneumococcal meningitis
0.653 0.347 0.000
G11 Hereditary ataxia
0.651 0.349 0.000
G70-G73 Diseases of myoneural junction and muscle
0.650 0.349 0.000
E14.8 With unspecified complications
0.000 0.352 0.648
E14.7 With multiple complications
0.000 0.352 0.648
E14.6 With other specified complications
0.000 0.352 0.648
E14.5 With peripheral circulatory complications
0.000 0.352 0.648
E14.2 Withrenal complications
0.000 0.352 0.648
E14.1 With ketoacidosis
0.000 0.352 0.648
E14.0 With coma
0.000 0.352 0.648
G37.5 Concentric sclerosis [Balo]
0.639 0.361 0.000
G37.4 Subacute necrotising myelitis
0.639 0.361 0.000
G37.2 Central pontine myelinolysis
0.639 0.361 0.000
G37.1 Central demyelination of corpus callosum
0.639 0.361 0.000
G37.0 Diffuse sclerosis
0.639 0.361 0.000
G82 Paraplegia and tetraplegia
0.636 0.364 0.000
K90 Intestinal malabsorption
0.000 0.367 0.633
G03.8 Meningitis due to other specified causes
0.632 0.368 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.632 0.368 0.000
G03.1 Chronic meningitis
0.632 0.368 0.000
G03.0 Nonpyogenic meningitis
0.632 0.368 0.000
L44 Other papulosquamous disorders
0.000 0.374 0.626
L41 Parapsoriasis
0.000 0.374 0.626
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.374 0.626
L42 Pityriasis rosea
0.000 0.374 0.626
E11.2 With renal complications
0.000 0.376 0.624
G31.0 Circumscribed brain atrophy
0.622 0.377 0.000
G10 Huntington's disease
0.620 0.379 0.000
L43.8 Other lichen planus
0.000 0.392 0.608
L43.3 Subacute (active) lichen planus
0.000 0.392 0.608
L43.2 Lichenoid drug reaction
0.000 0.392 0.608
L43.1 Bullous lichen planus
0.000 0.392 0.608
L43.0 Hypertrophic lichen planus
0.000 0.392 0.608
E14.4 With neurological complications
0.000 0.392 0.608
E11.4 With neurological complications
0.000 0.393 0.607
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.606 0.393 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.604 0.395 0.000
G92 Toxic encephalopathy
0.604 0.395 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.602 0.397 0.000
G40-G47 Episodic and paroxysmal disorders
0.602 0.398 0.000
G91 Hydrocephalus
0.596 0.404 0.000
G06.0 Intracranial abscess and granuloma
0.594 0.406 0.000
E13.8 With unspecified complications
0.000 0.407 0.593
E13.7 With multiple complications
0.000 0.407 0.593
E13.6 With other specified complications
0.000 0.407 0.593
E13.5 With peripheral circulatory complications
0.000 0.407 0.593
E13.4 With neurological complications
0.000 0.407 0.593
E13.3 With ophthalmic complications
0.000 0.407 0.593
E13.2 With renal complications
0.000 0.407 0.593
E13.1 With ketoacidosis
0.000 0.407 0.593
E13.0 With coma
0.000 0.407 0.593
G93.6 Cerebral oedema
0.589 0.411 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.588 0.412 0.000
G00.8 Other bacterial meningitis
0.587 0.412 0.000
G00.3 Staphylococcal meningitis
0.587 0.412 0.000
G00.2 Streptococcal meningitis
0.587 0.412 0.000
G00.0 Haemophilus meningitis
0.587 0.412 0.000
G93.5 Compression of brain
0.585 0.414 0.000
G82.1 Spastic paraplegia
0.582 0.418 0.000
E83.4 Disorders of magnesium metabolism
0.576 0.424 0.001
G25.0 Essential tremor
0.576 0.424 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.428 0.572
G06.1 Intraspinal abscess and granuloma
0.564 0.436 0.000
G80 Infantile cerebral palsy
0.563 0.437 0.000
G93.7 Reye's syndrome
0.561 0.439 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.556 0.444 0.000
G14 Postpolio syndrome
0.556 0.444 0.000
G11.4 Hereditary spastic paraplegia
0.555 0.445 0.000
G83.9 Paralytic syndrome, unspecified
0.550 0.450 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.550 0.450 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.454 0.546
G06.2 Extradural and subdural abscess, unspecified
0.546 0.454 0.000
G96.9 Disorder of central nervous system, unspecified
0.544 0.456 0.000
G96.8 Other specified disorders of central nervous system
0.544 0.456 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.537 0.462 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.537 0.462 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.537 0.462 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.537 0.463 0.000
G30.0 Alzheimer's disease with early onset
0.537 0.463 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.528 0.471 0.000
G24.8 Other dystonia
0.526 0.474 0.000
G90 Disorders of autonomic nervous system
0.523 0.477 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.521 0.479 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.9 Acute disseminated demyelination, unspecified
0.513 0.487 0.000
G36.8 Other specified acute disseminated demyelination
0.513 0.487 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.513 0.487 0.000
G36.0 Neuromyelitis optica [Devic]
0.513 0.487 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.510 0.490 0.000
G25.5 Other chorea
0.510 0.490 0.000
G25.4 Drug-induced chorea
0.510 0.490 0.000
G25.2 Other specified forms of tremor
0.510 0.490 0.000
G25.1 Drug-induced tremor
0.510 0.490 0.000
G83.4 Cauda equina syndrome
0.509 0.491 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.506 0.494 0.000
G04.1 Tropical spastic paraplegia
0.506 0.494 0.000
G04.0 Acute disseminated encephalitis
0.506 0.494 0.000
G93.2 Benign intracranial hypertension
0.506 0.494 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.504 0.496 0.000
G40 Epilepsy
0.504 0.496 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.501 0.498 0.000
G02.1 Meningitis in mycoses
0.501 0.498 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.501 0.498 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.498 0.502 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.498 0.502 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.498 0.502 0.000
G21.9 Secondary Parkinsonism, unspecified
0.497 0.502 0.000
G21.8 Other secondary Parkinsonism
0.497 0.502 0.000
G21.4 Vascular parkinsonism
0.497 0.502 0.000
G21.3 Postencephalitic Parkinsonism
0.497 0.502 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.497 0.502 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.497 0.502 0.000
G21.0 Malignant neuroleptic syndrome
0.497 0.502 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.497 0.502 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.497 0.502 0.000
G23.3 Multiple system atrophy, cerebellar type
0.497 0.502 0.000
G23.2 Striatonigral degeneration
0.497 0.502 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.497 0.502 0.000
G23.0 Hallervorden-Spatz disease
0.497 0.502 0.000
G83.8 Other specified paralytic syndromes
0.496 0.503 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.505 0.495
G46 Vascular syndromes of brain in cerebrovascular diseases
0.495 0.505 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.493 0.507 0.000
G72 Other myopathies
0.493 0.507 0.000
G24.4 Idiopathic orofacial dystonia
0.485 0.515 0.000
G24.3 Spasmodic torticollis
0.485 0.515 0.000
G24.2 Idiopathic nonfamilial dystonia
0.485 0.515 0.000
G24.1 Idiopathic familial dystonia
0.485 0.515 0.000
G24.0 Drug-induced dystonia
0.485 0.515 0.000
G11.9 Hereditary ataxia, unspecified
0.481 0.519 0.000
G83.1 Monoplegia of lower limb
0.481 0.519 0.000
G83.5 Locked-in syndrome
0.479 0.521 0.000
G83.3 Monoplegia, unspecified
0.479 0.521 0.000
G83.2 Monoplegia of upper limb
0.479 0.521 0.000
G83.0 Diplegia of upper limbs
0.479 0.521 0.000
G30.8 Other Alzheimer's disease
0.478 0.522 0.000
G30.1 Alzheimer's disease with late onset
0.478 0.522 0.000
G93.0 Cerebral cysts
0.475 0.524 0.000
G93.9 Disorder of brain, unspecified
0.472 0.528 0.000
G44 Other headache syndromes
0.472 0.528 0.000
G43 Migraine
0.472 0.528 0.000
G11.8 Other hereditary ataxias
0.467 0.533 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.467 0.533 0.000
G11.2 Late-onset cerebellar ataxia
0.467 0.533 0.000
G11.1 Early-onset cerebellar ataxia
0.467 0.533 0.000
G11.0 Congenital nonprogressive ataxia
0.467 0.533 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.466 0.533 0.000
G24.5 Blepharospasm
0.465 0.535 0.000
G91.1 Obstructive hydrocephalus
0.465 0.535 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.463 0.537 0.000
G82.4 Spastic tetraplegia
0.456 0.544 0.000
G82.3 Flaccid tetraplegia
0.456 0.544 0.000
G82.0 Flaccid paraplegia
0.456 0.544 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.546 0.454
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.546 0.454
K90.1 Tropical sprue
0.000 0.546 0.454
L41.9 Parapsoriasis, unspecified
0.000 0.551 0.449
L41.8 Other parapsoriasis
0.000 0.551 0.449
L41.5 Retiform parapsoriasis
0.000 0.551 0.449
L41.4 Large plaque parapsoriasis
0.000 0.551 0.449
L41.3 Small plaque parapsoriasis
0.000 0.551 0.449
L41.2 Lymphomatoid papulosis
0.000 0.551 0.449
L41.1 Pityriasis lichenoides chronica
0.000 0.551 0.449
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.551 0.449
L44.9 Papulosquamous disorder, unspecified
0.000 0.551 0.449
L44.8 Other specified papulosquamous disorders
0.000 0.551 0.449
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.551 0.449
L44.3 Lichen ruber moniliformis
0.000 0.551 0.449
L44.2 Lichen striatus
0.000 0.551 0.449
L44.1 Lichen nitidus
0.000 0.551 0.449
L44.0 Pityriasis rubra pilaris
0.000 0.551 0.449
G40.8 Other epilepsy
0.442 0.558 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.439 0.561 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.439 0.561 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.435 0.565 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.435 0.565 0.000
G24.9 Dystonia, unspecified
0.435 0.565 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.432 0.568 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.432 0.568 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.432 0.568 0.000
G94.1 Hydrocephalus in neoplastic disease
0.430 0.570 0.000
G81 Hemiplegia
0.428 0.572 0.000
G91.8 Other hydrocephalus
0.427 0.573 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.427 0.573 0.000
G91.2 Normal-pressure hydrocephalus
0.427 0.573 0.000
G91.0 Communicating hydrocephalus
0.427 0.573 0.000
G71 Primary disorders of muscles
0.425 0.574 0.000
K90.8 Other intestinal malabsorption
0.000 0.576 0.424
G43.8 Other migraine
0.423 0.577 0.000
G25.3 Myoclonus
0.421 0.579 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.420 0.580 0.000
G46.7 Other lacunar syndromes
0.419 0.581 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.417 0.583 0.000
G41 Status epilepticus
0.417 0.583 0.000
G82.5 Tetraplegia, unspecified
0.416 0.584 0.000
G70 Myasthenia gravis and other myoneural disorders
0.415 0.585 0.000
G80.8 Other infantile cerebral palsy
0.404 0.596 0.000
G80.4 Ataxic cerebral palsy
0.404 0.596 0.000
G80.3 Dyskinetic cerebral palsy
0.404 0.596 0.000
G80.2 Infantile hemiplegia
0.404 0.596 0.000
G80.1 Spastic diplegia
0.404 0.596 0.000
G80.0 Spastic cerebral palsy
0.404 0.596 0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.399 0.601 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.399 0.601 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.399 0.601 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.399 0.601 0.000
G80.9 Infantile cerebral palsy, unspecified
0.398 0.601 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.398 0.602 0.000
G97.8 Other postprocedural disorders of nervous system
0.398 0.602 0.000
G31.8 Other specified degenerative diseases of nervous system
0.389 0.610 0.001
G44.0 Cluster headache syndrome
0.389 0.611 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.387 0.613 0.000
G12 Spinal muscular atrophy and related syndromes
0.383 0.616 0.001
G90.8 Other disorders of autonomic nervous system
0.375 0.625 0.000
G90.4 Autonomic dysreflexia
0.375 0.625 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.375 0.625 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.375 0.625 0.000
G90.3 Multisystem degeneration
0.368 0.632 0.000
G91.9 Hydrocephalus, unspecified
0.368 0.632 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.361 0.639 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.361 0.639 0.000
G72.9 Myopathy, unspecified
0.359 0.641 0.000
G40.5 Special epileptic syndromes
0.359 0.641 0.000
G44.8 Other specified headache syndromes
0.358 0.642 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.355 0.645 0.000
G46.6 Pure sensory lacunar syndrome
0.355 0.645 0.000
G46.5 Pure motor lacunar syndrome
0.355 0.645 0.000
G46.4 Cerebellar stroke syndrome
0.355 0.645 0.000
G46.3 Brain stem stroke syndrome
0.355 0.645 0.000
G46.2 Posterior cerebral artery syndrome
0.355 0.645 0.000
G46.1 Anterior cerebral artery syndrome
0.355 0.645 0.000
G46.0 Middle cerebral artery syndrome
0.355 0.645 0.000
G72.8 Other specified myopathies
0.353 0.646 0.000
G72.3 Periodic paralysis
0.353 0.646 0.000
G72.2 Myopathy due to other toxic agents
0.353 0.646 0.000
G72.1 Alcoholic myopathy
0.353 0.646 0.000
G72.0 Drug-induced myopathy
0.353 0.646 0.000
G30.9 Alzheimer's disease, unspecified
0.352 0.647 0.000
G90.2 Horner's syndrome
0.352 0.648 0.000
G43.0 Migraine without aura [common migraine]
0.348 0.652 0.000
G95 Other diseases of spinal cord
0.348 0.652 0.000
J45 Asthma
0.000 0.659 0.341
G40.7 Petit mal, unspecified, without grand mal seizures
0.340 0.660 0.000
G44.3 Chronic posttraumatic headache
0.338 0.662 0.000
G44.1 Vascular headache, not elsewhere classified
0.338 0.662 0.000
G43.3 Complicated migraine
0.338 0.662 0.000
G43.2 Status migrainosus
0.338 0.662 0.000
G73.7 Myopathy other diseases classified elsewhere
0.334 0.665 0.000
G73.6 Myopathy in metabolic diseases
0.334 0.665 0.000
G73.5 Myopathy in endocrine diseases
0.334 0.665 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.334 0.665 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.334 0.665 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.334 0.665 0.000
G73.1 Eaton-Lambert syndrome
0.334 0.665 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.334 0.665 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.330 0.670 0.000
G82.2 Paraplegia, unspecified
0.326 0.673 0.000
G70.9 Myoneural disorder, unspecified
0.324 0.676 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.316 0.684 0.001
G71.1 Myotonic disorders
0.311 0.688 0.000
G44.2 Tension-type headache
0.307 0.693 0.000
G41.0 Grand mal status epilepticus
0.307 0.693 0.000
G81.1 Spastic hemiplegia
0.307 0.693 0.000
G81.0 Flaccid hemiplegia
0.307 0.693 0.000
G71.9 Primary disorder of muscle, unspecified
0.305 0.695 0.000
G71.8 Other primary disorders of muscles
0.305 0.695 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.305 0.695 0.000
G71.2 Congenital myopathies
0.305 0.695 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.301 0.699 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.301 0.699 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.002 0.699 0.299
G90.0 Idiopathic peripheral autonomic neuropathy
0.299 0.701 0.000
G41.8 Other status epilepticus
0.299 0.701 0.000
G41.2 Complex partial status epilepticus
0.299 0.701 0.000
G41.1 Petit mal status epilepticus
0.299 0.701 0.000
G70.8 Other specified myoneural disorders
0.297 0.702 0.000
G70.2 Congenital and developmental myasthenia
0.297 0.702 0.000
G70.1 Toxic myoneural disorders
0.297 0.702 0.000
G43.1 Migraine with aura [classical migraine]
0.297 0.703 0.000
G95.0 Syringomyelia and syringobulbia
0.292 0.708 0.000
G12.9 Spinal muscular atrophy, unspecified
0.275 0.724 0.001
G12.8 Other spinal muscular atrophies and related syndromes
0.275 0.724 0.001
G12.1 Other inherited spinal muscular atrophy
0.275 0.724 0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.275 0.724 0.001
G41.9 Status epilepticus, unspecified
0.275 0.725 0.000
E11.3 With ophthalmic complications
0.000 0.733 0.267
E78.2 Mixed hyperlipidaemia
0.001 0.736 0.264
G43.9 Migraine, unspecified
0.263 0.737 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.258 0.742 0.000
G71.0 Muscular dystrophy
0.256 0.744 0.000
G60 Hereditary and idiopathic neuropathy
0.251 0.748 0.001
J45.8 Mixed asthma
0.000 0.756 0.244
J45.1 Nonallergic asthma
0.000 0.756 0.244
G99.2 Myelopathy in diseases classified elsewhere
0.241 0.759 0.000
E70-E90 Metabolic disorders
0.015 0.766 0.219
E78.1 Pure hyperglyceridaemia
0.001 0.772 0.227
G64 Other disorders of peripheral nervous system
0.226 0.773 0.001
Chapter IV Endocrine, nutritional and metabolic diseases
0.003 0.775 0.222
G95.1 Vascular myelopathies
0.223 0.777 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.222 0.778 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.218 0.782 0.000
E78.6 Lipoprotein deficiency
0.001 0.784 0.214
E78.3 Hyperchylomicronaemia
0.001 0.784 0.214
G95.2 Cord compression, unspecified
0.208 0.791 0.000
G70.0 Myasthenia gravis
0.197 0.803 0.001
E78.4 Other hyperlipidaemia
0.001 0.809 0.190
J45.0 Predominantly allergic asthma
0.000 0.809 0.191
E78.8 Other disorders of lipoprotein metabolism
0.001 0.813 0.186
E85 Amyloidosis
0.009 0.818 0.174
G63 Polyneuropathy in diseases classified elsewhere
0.181 0.818 0.001
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.180 0.819 0.001
G60.3 Idiopathic progressive neuropathy
0.180 0.819 0.001
G60.2 Neuropathy in association with hereditary ataxia
0.180 0.819 0.001
G60.1 Refsum's disease
0.180 0.819 0.001
E84 Cystic fibrosis
0.011 0.832 0.157
E79 Disorders of purine and pyrimidine metabolism
0.011 0.832 0.157
E77 Disorders of glycoprotein metabolism
0.011 0.832 0.157
E76 Disorders of glycosaminoglycan metabolism
0.011 0.832 0.157
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.011 0.832 0.157
E74 Other disorders of carbohydrate metabolism
0.011 0.832 0.157
E72 Other disorders of amino-acid metabolism
0.011 0.832 0.157
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.011 0.832 0.157
E70 Disorders of aromatic amino-acid metabolism
0.011 0.832 0.157
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.011 0.832 0.157
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.002 0.832 0.166
G95.8 Other specified diseases of spinal cord
0.167 0.833 0.001
G81.9 Hemiplegia, unspecified
0.166 0.834 0.000
G95.9 Disease of spinal cord, unspecified
0.158 0.841 0.001
G47 Sleep disorders
0.158 0.842 0.000
E40-E46 Malnutrition
0.002 0.843 0.155
E78.9 Disorder of lipoprotein metabolism, unspecified
0.002 0.848 0.151
E73 Lactose intolerance
0.012 0.851 0.137
G40.9 Epilepsy, unspecified
0.147 0.853 0.000
E85.9 Amyloidosis, unspecified
0.005 0.857 0.138
G60.0 Hereditary motor and sensory neuropathy
0.140 0.859 0.001
E88 Other metabolic disorders
0.011 0.860 0.129
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.009 0.862 0.130
E80 Disorders of porphyrin and bilirubin metabolism
0.011 0.863 0.127
K51 Ulcerative colitis
0.137 0.863 0.000
E85.4 Organ-limited amyloidosis
0.006 0.865 0.129
K51.9 Ulcerative colitis, unspecified
0.134 0.866 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.132 0.868 0.000
E85.8 Other amyloidosis
0.006 0.869 0.125
E85.3 Secondary systemic amyloidosis
0.006 0.869 0.125
E85.2 Heredofamilial amyloidosis, unspecified
0.006 0.869 0.125
E85.1 Neuropathic heredofamilial amyloidosis
0.006 0.869 0.125
E85.0 Nonneuropathic heredofamilial amyloidosis
0.006 0.869 0.125
G63.8 Polyneuropathy in other diseases classified elsewhere
0.130 0.869 0.001
G63.6 Polyneuropathy in other musculoskeletal disorders
0.130 0.869 0.001
G63.5 Polyneuropathy in systemic connective tissue disorders
0.130 0.869 0.001
G63.4 Polyneuropathy in nutritional deficiency
0.130 0.869 0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.130 0.869 0.001
G63.1 Polyneuropathy in neoplastic disease
0.130 0.869 0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.130 0.869 0.001
G61 Inflammatory polyneuropathy
0.129 0.869 0.002
G45 Transient cerebral ischaemic attacks and related syndromes
0.129 0.871 0.000
G47.8 Other sleep disorders
0.127 0.873 0.000
E16 Other disorders of pancreatic internal secretion
0.001 0.873 0.126
K51.2 Ulcerative (chronic) proctitis
0.124 0.876 0.000
K51.8 Other ulcerative colitis
0.123 0.877 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.008 0.879 0.113
E70.8 Other disorders of aromatic amino-acid metabolism
0.008 0.879 0.113
E70.3 Albinism
0.008 0.879 0.113
E70.2 Disorders of tyrosine metabolism
0.008 0.879 0.113
E70.1 Other hyperphenylalaninaemias
0.008 0.879 0.113
E70.0 Classical phenylketonuria
0.008 0.879 0.113
E71.3 Disorders of fatty-acid metabolism
0.008 0.879 0.113
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.008 0.879 0.113
E71.1 Other disorders of branched-chain amino-acid metabolism
0.008 0.879 0.113
E71.0 Maple-syrup-urine disease
0.008 0.879 0.113
E72.9 Disorder of amino-acid metabolism, unspecified
0.008 0.879 0.113
E72.8 Other specified disorders of amino-acid metabolism
0.008 0.879 0.113
E72.5 Disorders of glycine metabolism
0.008 0.879 0.113
E72.4 Disorders of ornithine metabolism
0.008 0.879 0.113
E72.3 Disorders of lysine and hydroxylysine metabolism
0.008 0.879 0.113
E72.2 Disorders of urea cycle metabolism
0.008 0.879 0.113
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.008 0.879 0.113
E72.0 Disorders of amino-acid transport
0.008 0.879 0.113
E74.9 Disorder of carbohydrate metabolism, unspecified
0.008 0.879 0.113
E74.8 Other specified disorders of carbohydrate metabolism
0.008 0.879 0.113
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.008 0.879 0.113
E74.3 Other disorders of intestinal carbohydrate absorption
0.008 0.879 0.113
E74.2 Disorders of galactose metabolism
0.008 0.879 0.113
E74.1 Disorders of fructose metabolism
0.008 0.879 0.113
E74.0 Glycogen storage disease
0.008 0.879 0.113
E75.6 Lipid storage disorder, unspecified
0.008 0.879 0.113
E75.5 Other lipid storage disorders
0.008 0.879 0.113
E75.4 Neuronal ceroid lipofuscinosis
0.008 0.879 0.113
E75.3 Sphingolipidosis, unspecified
0.008 0.879 0.113
E75.2 Other sphingolipidosis
0.008 0.879 0.113
E75.1 Other gangliosidosis
0.008 0.879 0.113
E75.0 GM2 gangliosidosis
0.008 0.879 0.113
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.008 0.879 0.113
E76.8 Other disorders of glucosaminoglycan metabolism
0.008 0.879 0.113
E76.3 Mucopolysaccharidosis, unspecified
0.008 0.879 0.113
E76.2 Other mucopolysaccharidoses
0.008 0.879 0.113
E76.1 Mucopolysaccharidosis, type II
0.008 0.879 0.113
E76.0 Mucopolysaccharidosis, type I
0.008 0.879 0.113

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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