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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3095229
log Bayes Factor = 7.45423
Chromosome 6   position 31,480,272  (GRCh37) Explore rs3095229 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.009 0.991
E10-E14 Diabetes mellitus
0.000 0.009 0.991
E10.3 With ophthalmic complications
0.000 0.020 0.980
E06 Thyroiditis
0.000 0.049 0.951
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.058 0.942
E06.3 Autoimmune thyroiditis
0.000 0.077 0.923
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.105 0.895
E10.1 With ketoacidosis
0.000 0.119 0.881
E05.9 Thyrotoxicosis, unspecified
0.000 0.198 0.802
E40-E46 Malnutrition
0.000 0.236 0.764
E65-E68 Obesity and other hyperalimentation
0.000 0.237 0.763
E03.8 Other specified hypothyroidism
0.000 0.242 0.758
E10.5 With peripheral circulatory complications
0.000 0.263 0.737
E10.7 With multiple complications
0.000 0.284 0.716
E10.0 With coma
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.285 0.715
E70-E90 Metabolic disorders
0.000 0.289 0.711
E12 Malnutrition-related diabetes mellitus
0.000 0.289 0.710
E10.2 With renal complications
0.000 0.313 0.687
E10.8 With unspecified complications
0.000 0.317 0.683
E06.5 Other chronic thyroiditis
0.000 0.318 0.682
E06.4 Drug-induced thyroiditis
0.000 0.318 0.682
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.318 0.682
E06.1 Subacute thyroiditis
0.000 0.318 0.682
E06.0 Acute thyroiditis
0.000 0.318 0.682
E20-E35 Disorders of other endocrine glands
0.000 0.320 0.680
E10.6 With other specified complications
0.000 0.321 0.679
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.322 0.678
E05.5 Thyroid crisis or storm
0.000 0.325 0.675
E05.4 Thyrotoxicosis factitia
0.000 0.325 0.675
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.325 0.675
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.325 0.675
E86 Volume depletion
0.000 0.338 0.662
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.341 0.659
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.356 0.644
E06.9 Thyroiditis, unspecified
0.000 0.361 0.639
E65 Localised adiposity
0.000 0.370 0.630
E10.4 With neurological complications
0.000 0.372 0.627
E80.4 Gilbert's syndrome
0.000 0.378 0.622
E27 Other disorders of adrenal gland
0.000 0.386 0.614
E46 Unspecified protein-energy malnutrition
0.000 0.399 0.601
E73 Lactose intolerance
0.000 0.410 0.590
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.417 0.583
E28 Ovarian dysfunction
0.000 0.431 0.569
E27.1 Primary adrenocortical insufficiency
0.000 0.434 0.566
E14 Unspecified diabetes mellitus
0.000 0.436 0.564
E05.8 Other thyrotoxicosis
0.000 0.446 0.554
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.452 0.548
E45 Retarded development following protein-energy malnutrition
0.000 0.452 0.548
E43 Unspecified severe protein-energy malnutrition
0.000 0.452 0.548
E42 Marasmic kwashiorkor
0.000 0.452 0.548
E41 Nutritional marasmus
0.000 0.452 0.548
E40 Kwashiorkor
0.000 0.452 0.548
E67 Other hyperalimentation
0.000 0.453 0.547
E68 Sequelae of hyperalimentation
0.000 0.453 0.547
E50-E64 Other nutritional deficiencies
0.000 0.464 0.536
E13 Other specified diabetes mellitus
0.001 0.481 0.518
E88 Other metabolic disorders
0.000 0.482 0.518
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E84 Cystic fibrosis
0.000 0.490 0.510
E79 Disorders of purine and pyrimidine metabolism
0.000 0.490 0.510
E77 Disorders of glycoprotein metabolism
0.000 0.490 0.510
E76 Disorders of glycosaminoglycan metabolism
0.000 0.490 0.510
E72 Other disorders of amino-acid metabolism
0.000 0.490 0.510
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.490 0.510
E70 Disorders of aromatic amino-acid metabolism
0.000 0.490 0.510
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.490 0.510
E12.9 Without complications
0.000 0.490 0.509
E12.8 With unspecified complications
0.000 0.490 0.509
E12.7 With multiple complications
0.000 0.490 0.509
E12.6 With other specified complications
0.000 0.490 0.509
E12.5 With peripheral circulatory complications
0.000 0.490 0.509
E12.4 With neurological complications
0.000 0.490 0.509
E12.3 With ophthalmic complications
0.000 0.490 0.509
E12.2 With renal complications
0.000 0.490 0.509
E12.1 With ketoacidosis
0.000 0.490 0.509
E12.0 With coma
0.000 0.490 0.509
E73.9 Lactose intolerance, unspecified
0.000 0.497 0.503
E20 Hypoparathyroidism
0.000 0.498 0.501
E66 Obesity
0.000 0.503 0.497
E07 Other disorders of thyroid
0.000 0.503 0.497
E27.2 Addisonian crisis
0.000 0.508 0.491
E28.2 Polycystic ovarian syndrome
0.000 0.509 0.491
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.512 0.488
E32 Diseases of thymus
0.000 0.512 0.488
E31 Polyglandular dysfunction
0.000 0.512 0.488
E30 Disorders of puberty, not elsewhere classified
0.000 0.512 0.488
E25 Adrenogenital disorders
0.000 0.512 0.488
E24 Cushing's syndrome
0.000 0.514 0.485
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.520 0.480
E26 Hyperaldosteronism
0.000 0.524 0.476
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.527 0.473
E80.6 Other disorders of bilirubin metabolism
0.000 0.527 0.473
E80.5 Crigler-Najjar syndrome
0.000 0.527 0.473
E80.3 Defects of catalase and peroxydase
0.000 0.527 0.473
E80.2 Other porphyria
0.000 0.527 0.473
E80.1 Porphyria cutanea tarda
0.000 0.527 0.473
E80.0 Hereditary erythropoietic porphyria
0.000 0.527 0.473
E74 Other disorders of carbohydrate metabolism
0.000 0.527 0.473
E66.8 Other obesity
0.000 0.528 0.472
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.533 0.467
E27.8 Other specified disorders of adrenal gland
0.000 0.538 0.462
E27.9 Disorder of adrenal gland, unspecified
0.000 0.545 0.455
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.554 0.446
E27.5 Adrenomedullary hyperfunction
0.000 0.559 0.441
E27.0 Other adrenocortical overactivity
0.000 0.559 0.441
E89.0 Postprocedural hypothyroidism
0.000 0.576 0.424
E73.8 Other lactose intolerance
0.000 0.577 0.423
E73.1 Secondary lactase deficiency
0.000 0.577 0.423
E73.0 Congenital lactase deficiency
0.000 0.577 0.423
E14.3 With ophthalmic complications
0.000 0.578 0.422
E15 Nondiabetic hypoglycaemic coma
0.000 0.582 0.418
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.590 0.410
E22 Hyperfunction of pituitary gland
0.000 0.590 0.410
E28.9 Ovarian dysfunction, unspecified
0.000 0.592 0.408
E28.8 Other ovarian dysfunction
0.000 0.592 0.408
E28.1 Androgen excess
0.000 0.592 0.408
E28.0 Oestrogen excess
0.000 0.592 0.408
E29 Testicular dysfunction
0.000 0.594 0.406
E28.3 Primary ovarian failure
0.000 0.594 0.406
E14.8 With unspecified complications
0.000 0.596 0.404
E14.7 With multiple complications
0.000 0.596 0.404
E14.6 With other specified complications
0.000 0.596 0.404
E14.5 With peripheral circulatory complications
0.000 0.596 0.404
E14.4 With neurological complications
0.000 0.596 0.404
E14.1 With ketoacidosis
0.000 0.596 0.404
E14.0 With coma
0.000 0.596 0.404
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.601 0.398
E34 Other endocrine disorders
0.000 0.602 0.397
E04 Other non-toxic goitre
0.000 0.606 0.394
E44.1 Mild protein-energy malnutrition
0.000 0.607 0.393
E44.0 Moderate protein-energy malnutrition
0.000 0.607 0.393
E67.8 Other specified hyperalimentation
0.000 0.608 0.392
E67.3 Hypervitaminosis D
0.000 0.608 0.392
E67.2 Megavitamin-B6 syndrome
0.000 0.608 0.392
E67.1 Hypercarotenaemia
0.000 0.608 0.392
E67.0 Hypervitaminosis A
0.000 0.608 0.392
E21.3 Hyperparathyroidism, unspecified
0.000 0.610 0.389
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.616 0.384
E63 Other nutritional deficiencies
0.000 0.616 0.384
E56 Other vitamin deficiencies
0.000 0.616 0.384
E51 Thiamine deficiency
0.000 0.616 0.384
E50 Vitamin A deficiency
0.000 0.616 0.384
E60 Dietary zinc deficiency
0.000 0.616 0.384
E59 Dietary selenium deficiency
0.000 0.616 0.384
E58 Dietary calcium deficiency
0.000 0.616 0.384
E54 Ascorbic acid deficiency
0.000 0.616 0.384
E52 Niacin deficiency [pellagra]
0.000 0.616 0.384
E53 Deficiency of other B group vitamins
0.000 0.621 0.379
E20.9 Hypoparathyroidism, unspecified
0.000 0.626 0.373
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.627 0.373
E13.8 With unspecified complications
0.001 0.628 0.372
E13.7 With multiple complications
0.001 0.628 0.372
E13.6 With other specified complications
0.001 0.628 0.372
E13.5 With peripheral circulatory complications
0.001 0.628 0.372
E13.4 With neurological complications
0.001 0.628 0.372
E13.3 With ophthalmic complications
0.001 0.628 0.372
E13.2 With renal complications
0.001 0.628 0.372
E13.1 With ketoacidosis
0.001 0.628 0.372
E13.0 With coma
0.001 0.628 0.372
E88.9 Metabolic disorder, unspecified
0.000 0.628 0.372
E88.8 Other specified metabolic disorders
0.000 0.628 0.372
E88.3 Tumour lysis syndrome
0.000 0.628 0.372
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.628 0.372
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.634 0.366
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.634 0.366
E70.3 Albinism
0.000 0.634 0.366
E70.2 Disorders of tyrosine metabolism
0.000 0.634 0.366
E70.1 Other hyperphenylalaninaemias
0.000 0.634 0.366
E70.0 Classical phenylketonuria
0.000 0.634 0.366
E71.3 Disorders of fatty-acid metabolism
0.000 0.634 0.366
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.634 0.366
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.634 0.366
E71.0 Maple-syrup-urine disease
0.000 0.634 0.366
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.634 0.366
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.634 0.366
E72.5 Disorders of glycine metabolism
0.000 0.634 0.366
E72.4 Disorders of ornithine metabolism
0.000 0.634 0.366
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.634 0.366
E72.2 Disorders of urea cycle metabolism
0.000 0.634 0.366
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.634 0.366
E72.0 Disorders of amino-acid transport
0.000 0.634 0.366
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.634 0.366
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.634 0.366
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.634 0.366
E76.2 Other mucopolysaccharidoses
0.000 0.634 0.366
E76.1 Mucopolysaccharidosis, type II
0.000 0.634 0.366
E76.0 Mucopolysaccharidosis, type I
0.000 0.634 0.366
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.634 0.366
E77.8 Other disorders of glycoprotein metabolism
0.000 0.634 0.366
E77.1 Defects in glycoprotein degradation
0.000 0.634 0.366
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.634 0.366
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.634 0.366
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.634 0.366
E79.1 Lesch-Nyhan syndrome
0.000 0.634 0.366
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.634 0.366
E84.9 Cystic fibrosis, unspecified
0.000 0.634 0.366
E84.8 Cystic fibrosis with other manifestations
0.000 0.634 0.366
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.634 0.366
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.634 0.366
E23 Hypofunction and other disorders of pituitary gland
0.000 0.635 0.365
E20.8 Other hypoparathyroidism
0.000 0.640 0.360
E20.1 Pseudohypoparathyroidism
0.000 0.640 0.360
E20.0 Idiopathic hypoparathyroidism
0.000 0.640 0.360
E85 Amyloidosis
0.000 0.641 0.359
E83 Disorders of mineral metabolism
0.000 0.641 0.359
E66.1 Drug-induced obesity
0.000 0.643 0.357
E07.1 Dyshormogenetic goitre
0.000 0.643 0.356
E07.0 Hypersecretion of calcitonin
0.000 0.643 0.356
E14.2 Withrenal complications
0.000 0.645 0.355
E07.8 Other specified disorders of thyroid
0.000 0.648 0.352
E25.9 Adrenogenital disorder, unspecified
0.000 0.650 0.350
E25.8 Other adrenogenital disorders
0.000 0.650 0.350
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.650 0.350
E30.9 Disorder of puberty, unspecified
0.000 0.650 0.350
E30.8 Other disorders of puberty
0.000 0.650 0.350
E30.1 Precocious puberty
0.000 0.650 0.350
E30.0 Delayed puberty
0.000 0.650 0.350
E31.9 Polyglandular dysfunction, unspecified
0.000 0.650 0.350
E31.8 Other polyglandular dysfunction
0.000 0.650 0.350
E31.1 Polyglandular hyperfunction
0.000 0.650 0.350
E31.0 Autoimmune polyglandular failure
0.000 0.650 0.350
E32.9 Disease of thymus, unspecified
0.000 0.650 0.350
E32.8 Other diseases of thymus
0.000 0.650 0.350
E32.1 Abscess of thymus
0.000 0.650 0.350
E32.0 Persistent hyperplasia of thymus
0.000 0.650 0.350
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.650 0.350
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.650 0.350
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.650 0.350
E61 Deficiency of other nutrient elements
0.000 0.651 0.349
E24.8 Other Cushing's syndrome
0.000 0.652 0.348
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.652 0.348
E24.3 Ectopic ACTH syndrome
0.000 0.652 0.348
E24.2 Drug-induced Cushing's syndrome
0.000 0.652 0.348
E24.1 Nelson's syndrome
0.000 0.652 0.348
E24.0 Pituitary-dependent Cushing's disease
0.000 0.652 0.348
E24.9 Cushing's syndrome, unspecified
0.000 0.654 0.346
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.656 0.344
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.656 0.344
E89.5 Postprocedural testicular hypofunction
0.000 0.656 0.344
E89.4 Postprocedural ovarian failure
0.000 0.656 0.344
E89.1 Postprocedural hypoinsulinaemia
0.000 0.656 0.344
E26.9 Hyperaldosteronism, unspecified
0.000 0.659 0.341
E26.8 Other hyperaldosteronism
0.000 0.659 0.341
E26.1 Secondary hyperaldosteronism
0.000 0.659 0.341
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.661 0.339
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.661 0.339
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.661 0.339
E74.2 Disorders of galactose metabolism
0.000 0.661 0.339
E74.1 Disorders of fructose metabolism
0.000 0.661 0.339
E74.0 Glycogen storage disease
0.000 0.661 0.339
E89.3 Postprocedural hypopituitarism
0.000 0.663 0.337
E75.6 Lipid storage disorder, unspecified
0.000 0.665 0.335
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.665 0.335
E75.3 Sphingolipidosis, unspecified
0.000 0.665 0.335
E75.2 Other sphingolipidosis
0.000 0.665 0.335
E75.1 Other gangliosidosis
0.000 0.665 0.335
E75.0 GM2 gangliosidosis
0.000 0.665 0.335
E22.0 Acromegaly and pituitary gigantism
0.000 0.666 0.333
E66.0 Obesity due to excess calories
0.000 0.669 0.331
E04.0 Non-toxic diffuse goitre
0.000 0.670 0.330
E88.2 Lipomatosis, not elsewhere classified
0.000 0.670 0.330
E26.0 Primary hyperaldosteronism
0.000 0.671 0.329
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.678 0.321
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.680 0.320
E21.4 Other specified disorders of parathyroid gland
0.000 0.680 0.320
E21.2 Other hyperparathyroidism
0.000 0.680 0.320
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.680 0.320
E83.3 Disorders of phosphorus metabolism
0.000 0.683 0.317
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.698 0.301
E14.9 Without complications
0.000 0.701 0.299
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.706 0.294
E22.8 Other hyperfunction of pituitary gland
0.000 0.706 0.294
E75.5 Other lipid storage disorders
0.000 0.707 0.292
E29.9 Testicular dysfunction, unspecified
0.000 0.709 0.291
E29.8 Other testicular dysfunction
0.000 0.709 0.291
E29.0 Testicular hyperfunction
0.000 0.709 0.291
E16 Other disorders of pancreatic internal secretion
0.000 0.709 0.290
E34.5 Androgen resistance syndrome
0.000 0.715 0.285
E34.4 Constitutional tall stature
0.000 0.715 0.285
E34.3 Short stature, not elsewhere classified
0.000 0.715 0.285
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.715 0.285
E34.1 Other hypersecretion of intestinal hormones
0.000 0.715 0.285
E04.8 Other specified non-toxic goitre
0.000 0.717 0.283
E55 Vitamin D deficiency
0.000 0.719 0.280
E50.9 Vitamin A deficiency, unspecified
0.000 0.724 0.276
E50.8 Other manifestations of vitamin A deficiency
0.000 0.724 0.276
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.724 0.276
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.724 0.276
E50.5 Vitamin A deficiency with night blindness
0.000 0.724 0.276
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.724 0.276
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.724 0.276
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.724 0.276
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.724 0.276
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.724 0.276
E51.9 Thiamine deficiency, unspecified
0.000 0.724 0.276
E51.8 Other manifestations of thiamine deficiency
0.000 0.724 0.276
E51.2 Wernicke's encephalopathy
0.000 0.724 0.276
E51.1 Beriberi
0.000 0.724 0.276
E56.9 Vitamin deficiency, unspecified
0.000 0.724 0.276
E56.8 Deficiency of other vitamins
0.000 0.724 0.276
E56.1 Deficiency of vitamin K
0.000 0.724 0.276
E56.0 Deficiency of vitamin E
0.000 0.724 0.276
E63.9 Nutritional deficiency, unspecified
0.000 0.724 0.276
E63.8 Other specified nutritional deficiencies
0.000 0.724 0.276
E63.1 Imbalance of constituents of food intake
0.000 0.724 0.276
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.724 0.276
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.724 0.276
E64.8 Sequelae of other nutritional deficiencies
0.000 0.724 0.276
E64.3 Sequelae of rickets
0.000 0.724 0.276
E64.2 Sequelae of vitamin C deficiency
0.000 0.724 0.276
E64.1 Sequelae of vitamin A deficiency
0.000 0.724 0.276
E64.0 Sequelae of protein-energy malnutrition
0.000 0.724 0.276
E53.8 Deficiency of other specified B group vitamins
0.000 0.725 0.275
E53.1 Pyridoxine deficiency
0.000 0.728 0.272
E53.0 Riboflavin deficiency
0.000 0.728 0.272
E34.8 Other specified endocrine disorders
0.000 0.730 0.270
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.730 0.270
E87.7 Fluid overload
0.000 0.731 0.269
E85.4 Organ-limited amyloidosis
0.000 0.731 0.269
E34.0 Carcinoid syndrome
0.000 0.735 0.265
E53.9 Vitamin B deficiency, unspecified
0.000 0.738 0.262
E23.7 Disorder of pituitary gland, unspecified
0.000 0.738 0.262
E23.6 Other disorders of pituitary gland
0.000 0.738 0.262
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.738 0.262
E23.1 Drug-induced hypopituitarism
0.000 0.738 0.262
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.742 0.257
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.742 0.257
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.742 0.257
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.743 0.257
E83.8 Other disorders of mineral metabolism
0.000 0.743 0.257
E83.2 Disorders of zinc metabolism
0.000 0.743 0.257
E83.0 Disorders of copper metabolism
0.000 0.743 0.257
E61.1 Iron deficiency
0.000 0.743 0.257
E61.9 Deficiency of nutrient element, unspecified
0.000 0.749 0.250
E61.8 Deficiency of other specified nutrient elements
0.000 0.749 0.250
E61.7 Deficiency of multiple nutrient elements
0.000 0.749 0.250
E61.6 Vanadium deficiency
0.000 0.749 0.250
E61.5 Molybdenum deficiency
0.000 0.749 0.250
E61.4 Chromium deficiency
0.000 0.749 0.250
E61.3 Manganese deficiency
0.000 0.749 0.250
E61.0 Copper deficiency
0.000 0.749 0.250
E22.1 Hyperprolactinaemia
0.000 0.752 0.248
E87.2 Acidosis
0.000 0.752 0.248
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.753 0.247
E34.9 Endocrine disorder, unspecified
0.000 0.754 0.245
E83.4 Disorders of magnesium metabolism
0.000 0.761 0.239
E23.2 Diabetes insipidus
0.000 0.763 0.237
E87.0 Hyperosmolality and hypernatraemia
0.000 0.766 0.234
E04.1 Non-toxic single thyroid nodule
0.000 0.768 0.232
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.770 0.230
E87.4 Mixed disorder of acid-base balance
0.000 0.771 0.229
E85.9 Amyloidosis, unspecified
0.001 0.775 0.225
E85.8 Other amyloidosis
0.001 0.786 0.213
E87.3 Alkalosis
0.000 0.787 0.213
E29.1 Testicular hypofunction
0.000 0.790 0.209
E85.3 Secondary systemic amyloidosis
0.001 0.790 0.209
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.792 0.208
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.792 0.208
E16.4 Abnormal secretion of gastrin
0.000 0.792 0.208
E16.3 Increased secretion of glucagon
0.000 0.792 0.208
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.792 0.208
E61.2 Magnesium deficiency
0.000 0.795 0.205
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.798 0.201
E55.0 Rickets, active
0.000 0.799 0.201
E04.2 Non-toxic multinodular goitre
0.000 0.814 0.186
E87.6 Hypokalaemia
0.000 0.817 0.183
E23.0 Hypopituitarism
0.000 0.817 0.183
E13.9 Without complications
0.001 0.819 0.180
E21.0 Primary hyperparathyroidism
0.000 0.822 0.177
E83.1 Disorders of iron metabolism
0.000 0.825 0.175
E16.1 Other hypoglycaemia
0.000 0.829 0.170
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.834 0.166
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.835 0.165
M06.9 Rheumatoid arthritis, unspecified
0.000 0.843 0.157
E89.2 Postprocedural hypoparathyroidism
0.002 0.844 0.154
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.848 0.152
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.849 0.151
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.850 0.150
E07.9 Disorder of thyroid, unspecified
0.001 0.851 0.148
E16.2 Hypoglycaemia, unspecified
0.000 0.853 0.146
E11 Non-insulin-dependent diabetes mellitus
0.000 0.858 0.142
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.861 0.139
G35 Multiple sclerosis
0.000 0.865 0.135
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.867 0.133
E78.1 Pure hyperglyceridaemia
0.000 0.871 0.129
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.872 0.128
E78.3 Hyperchylomicronaemia
0.000 0.881 0.119
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.882 0.118
E04.9 Non-toxic goitre, unspecified
0.000 0.882 0.118
E78.4 Other hyperlipidaemia
0.000 0.882 0.118
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.882 0.118
E11.3 With ophthalmic complications
0.000 0.884 0.116
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.886 0.114
E11.8 With unspecified complications
0.000 0.886 0.114
M06 Other rheumatoid arthritis
0.000 0.887 0.113
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.887 0.113
E78.6 Lipoprotein deficiency
0.000 0.888 0.112
E11.1 With ketoacidosis
0.000 0.888 0.111
M06.0 Seronegative rheumatoid arthritis
0.000 0.892 0.108
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.894 0.106
E11.0 With coma
0.000 0.897 0.102
E11.7 With multiple complications
0.000 0.898 0.102
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.899 0.101
E11.2 With renal complications
0.000 0.900 0.100
E87.5 Hyperkalaemia
0.000 0.902 0.098
E55.9 Vitamin D deficiency, unspecified
0.001 0.902 0.097
E78.2 Mixed hyperlipidaemia
0.000 0.903 0.097
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.908 0.092
E78.8 Other disorders of lipoprotein metabolism
0.000 0.912 0.087
Z88.0 Personal history of allergy to penicillin
0.087 0.913 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.919 0.081
M06.2 Rheumatoid bursitis
0.000 0.919 0.081
M06.1 Adult-onset Still's disease
0.000 0.919 0.081
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.922 0.077
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.922 0.077
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.922 0.077
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.922 0.077
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.922 0.077
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.922 0.077
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.922 0.077
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.922 0.077
M06.3 Rheumatoid nodule
0.000 0.923 0.077
E83.5 Disorders of calcium metabolism
0.000 0.927 0.073
E11.6 With other specified complications
0.000 0.930 0.070
M06.4 Inflammatory polyarthropathy
0.001 0.938 0.061
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.941 0.058
M06.18 Adult-onset Still's disease (Other)
0.000 0.941 0.058
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.941 0.058
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.941 0.058
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.941 0.058
M06.14 Adult-onset Still's disease (Hand)
0.000 0.941 0.058
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.941 0.058
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.941 0.058
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.941 0.058
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.941 0.058
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.941 0.058
M06.28 Rheumatoid bursitis (Other)
0.000 0.941 0.058
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.941 0.058
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.941 0.058
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.941 0.058
M06.24 Rheumatoid bursitis (Hand)
0.000 0.941 0.058
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.941 0.058
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.941 0.058
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.941 0.058
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.941 0.058
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.941 0.058
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.941 0.058
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.941 0.058
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.941 0.058
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.941 0.058
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.941 0.058
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.941 0.058
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.941 0.058
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.941 0.058
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.941 0.058
M06.34 Rheumatoid nodule (Hand)
0.000 0.943 0.056
E11.5 With peripheral circulatory complications
0.000 0.944 0.056
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.944 0.055
M06.38 Rheumatoid nodule (Other)
0.000 0.944 0.055
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.944 0.055
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.944 0.055
M06.33 Rheumatoid nodule (Forearm)
0.000 0.944 0.055
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.944 0.055
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.944 0.055
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.944 0.055
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.949 0.051
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.950 0.050
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.955 0.044
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.956 0.044
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.001 0.956 0.044
M06.46 Inflammatory polyarthropathy (Lower leg)
0.001 0.956 0.044
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.001 0.956 0.044
M06.44 Inflammatory polyarthropathy (Hand)
0.001 0.956 0.044
M06.43 Inflammatory polyarthropathy (Forearm)
0.001 0.956 0.044
M06.42 Inflammatory polyarthropathy (Upper arm)
0.001 0.956 0.044
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.001 0.956 0.044
G36 Other acute disseminated demyelination
0.000 0.963 0.037
H40.9 Glaucoma, unspecified
0.000 0.964 0.036
H40 Glaucoma
0.000 0.965 0.035
G37 Other demyelinating diseases of central nervous system
0.000 0.966 0.034

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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