TreeWAS – Variant ID: rs3099557

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.002	0.998
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.002	0.998
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.013	0.987
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.014	0.986
T42.4 Benzodiazepines	0.000	0.016	0.984
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.046	0.954
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.063	0.937
T42.1 Iminostilbenes	0.000	0.106	0.894
T39.1 4-Aminophenol derivatives	0.000	0.106	0.894
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.106	0.894
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.110	0.890
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.114	0.886
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.162	0.838
T45.0 Antiallergic and antiemetic drugs	0.000	0.176	0.824
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.194	0.806
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.209	0.791
T42.0 Hydantoin derivatives	0.000	0.216	0.784
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.236	0.764
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.242	0.758
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.243	0.757
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.244	0.756
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.249	0.751
T38.1 Thyroid hormones and substitutes	0.000	0.250	0.750
T42.3 Barbiturates	0.000	0.251	0.749
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.254	0.746
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.265	0.735
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.268	0.732
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.284	0.716
T42.2 Succinimides and oxazolidinediones	0.000	0.284	0.716
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.285	0.715
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.286	0.714
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.288	0.712
T39.4 Antirheumatics, not elsewhere classified	0.000	0.292	0.708
T39.2 Pyrazolone derivatives	0.000	0.292	0.708
T39.0 Salicylates	0.000	0.295	0.705
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.298	0.702
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.300	0.700
T45.5 Anticoagulants	0.000	0.304	0.696
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.306	0.694
T40.2 Other opioids	0.000	0.319	0.681
T38.5 Other oestrogens and progestogens	0.000	0.324	0.675
T38.9 Other and unspecified hormone antagonists	0.000	0.328	0.672
T38.7 Androgens and anabolic congeners	0.000	0.328	0.672
T38.4 Oral contraceptives	0.000	0.328	0.672
T38.2 Antithyroid drugs	0.000	0.328	0.672
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.328	0.672
T38.0 Glucocorticoids and synthetic analogues	0.000	0.334	0.666
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.344	0.656
T36 Poisoning by systemic antibiotics	0.000	0.350	0.650
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.357	0.643
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.359	0.641
T46.7 Peripheral vasodilators	0.000	0.359	0.641
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.365	0.635
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.365	0.635
T45.8 Other primarily systemic and haematological agents	0.000	0.365	0.635
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.365	0.635
T45.6 Fibrinolysis-affecting drugs	0.000	0.365	0.635
T45.3 Enzymes, not elsewhere classified	0.000	0.365	0.635
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.380	0.620
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.381	0.619
T45.4 Iron and its compounds	0.000	0.387	0.613
T40.5 Cocaine	0.000	0.394	0.606
T40.1 Heroin	0.000	0.395	0.605
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.395	0.605
T40.4 Other synthetic narcotics	0.000	0.398	0.602
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.399	0.601
T37.5 Antiviral drugs	0.000	0.399	0.601
T37.4 Anthelminthics	0.000	0.399	0.601
T37.3 Other antiprotozoal drugs	0.000	0.399	0.601
T37.1 Antimycobacterial drugs	0.000	0.399	0.601
T37.0 Sulphonamides	0.000	0.399	0.601
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.403	0.597
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.404	0.596
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.406	0.594
T47.2 Stimulant laxatives	0.000	0.412	0.588
T45.2 Vitamins, not elsewhere classified	0.000	0.414	0.586
T43.2 Other and unspecified antidepressants	0.000	0.415	0.585
T46.1 Calcium-channel blockers	0.000	0.416	0.584
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.418	0.582
T47.6 Antidiarrhoeal drugs	0.000	0.420	0.580
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.422	0.578
T40.8 Lysergide [LSD]	0.000	0.422	0.578
T40.7 Cannabis (derivatives)	0.000	0.422	0.578
T40.0 Opium	0.000	0.422	0.578
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.424	0.575
T48.5 Anti-common-cold drugs	0.000	0.431	0.569
T50.1 Loop [high-ceiling] diuretics	0.000	0.435	0.565
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.437	0.563
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.443	0.557
T40.3 Methadone	0.000	0.450	0.550
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.452	0.548
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.452	0.548
T47.7 Emetics	0.000	0.452	0.548
T47.5 Digestants	0.000	0.452	0.548
T47.3 Saline and osmotic laxatives	0.000	0.452	0.548
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.452	0.548
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.454	0.546
T47.4 Other laxatives	0.000	0.455	0.545
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.456	0.543
T48.4 Expectorants	0.000	0.456	0.543
T48.3 Antitussives	0.000	0.456	0.543
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.456	0.543
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.456	0.543
T48.0 Oxytocic drugs	0.000	0.456	0.543
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.457	0.542
T43.9 Psychotropic drug, unspecified	0.000	0.469	0.531
T50.8 Diagnostic agents	0.000	0.472	0.527
T50.7 Analeptics and opioid receptor antagonists	0.000	0.473	0.527
T50.5 Appetite depressants	0.000	0.473	0.527
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.473	0.527
T50.0 Mineralocorticoids and their antagonists	0.000	0.473	0.527
T41.5 Therapeutic gases	0.000	0.487	0.513
T41.4 Anaesthetic, unspecified	0.000	0.487	0.513
T41.3 Local anaesthetics	0.000	0.487	0.513
T41.2 Other and unspecified general anaesthetics	0.000	0.487	0.513
T41.1 Intravenous anaesthetics	0.000	0.487	0.513
T41.0 Inhaled anaesthetics	0.000	0.487	0.513
T49.9 Topical agent, unspecified	0.000	0.489	0.511
T49.8 Other topical agents	0.000	0.489	0.511
T49.7 Dental drugs, topically applied	0.000	0.489	0.511
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.489	0.511
T49.5 Ophthalmological drugs and preparations	0.000	0.489	0.511
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.489	0.511
T49.3 Emollients, demulcents and protectants	0.000	0.489	0.511
T49.2 Local astringents and local detergents	0.000	0.489	0.511
T49.1 Antipruritics	0.000	0.489	0.511
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.492	0.508
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.493	0.507
T50.4 Drugs affecting uric acid metabolism	0.000	0.495	0.504
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.498	0.502
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.498	0.502
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.498	0.502
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.498	0.502
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.498	0.502
T44.0 Anticholinesterase agents	0.000	0.498	0.502
T43.6 Psychostimulants with abuse potential	0.000	0.504	0.495
T47.0 Histamine H(2)-receptor antagonists	0.000	0.508	0.492
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.513	0.486
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.513	0.486
T40.6 Other and unspecified narcotics	0.000	0.519	0.480
T36.4 Tetracyclines	0.000	0.531	0.469
T36.9 Systemic antibiotic, unspecified	0.000	0.534	0.466
T36.7 Antifungal antibiotics, systemically used	0.000	0.534	0.466
T36.6 Rifamycins	0.000	0.534	0.466
T36.5 Aminoglycosides	0.000	0.534	0.466
T36.2 Chloramphenicol group	0.000	0.534	0.466
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.543	0.457
T36.3 Macrolides	0.000	0.555	0.444
T36.8 Other systemic antibiotics	0.000	0.557	0.443
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.567	0.432
T36.0 Penicillins	0.000	0.576	0.424
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.610	0.390
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.617	0.383
E10.3 With ophthalmic complications	0.000	0.939	0.061
E10 Insulin-dependent diabetes mellitus	0.000	0.941	0.059
E10.4 With neurological complications	0.000	0.942	0.058
E10.5 With peripheral circulatory complications	0.000	0.944	0.056
E10.2 With renal complications	0.000	0.951	0.049
E10.1 With ketoacidosis	0.000	0.951	0.049
E10.8 With unspecified complications	0.000	0.953	0.046
E10.6 With other specified complications	0.000	0.957	0.043
E10.0 With coma	0.000	0.957	0.043
E10.7 With multiple complications	0.000	0.958	0.042
D41.4 Bladder	0.000	0.990	0.010
C90.0 Multiple myeloma	0.000	0.990	0.010
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.010	0.990	0.000
E10.9 Without complications	0.000	0.991	0.009
Y86 Sequelae of other accidents	0.008	0.992	0.000
Q63.0 Accessory kidney	0.000	0.992	0.008
K59.0 Constipation	0.008	0.992	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.992	0.008
Q63 Other congenital malformations of kidney	0.000	0.992	0.007
Q60-Q64 Congenital malformations of the urinary system	0.000	0.993	0.007
Q76 Congenital malformations of spine and bony thorax	0.000	0.993	0.007
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.000	0.993	0.007
K59.3 Megacolon, not elsewhere classified	0.007	0.993	0.000
Q05.9 Spina bifida, unspecified	0.000	0.993	0.007
Q05 Spina bifida	0.000	0.993	0.007
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.993	0.006
Q00-Q07 Congenital malformations of the nervous system	0.000	0.993	0.006
K10.2 Inflammatory conditions of jaws	0.000	0.993	0.007
Q61 Cystic kidney disease	0.000	0.994	0.006
Q63.2 Ectopic kidney	0.000	0.994	0.006
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.994	0.006
Q62.5 Duplication of ureter	0.000	0.994	0.006
Y85.0 Sequelae of motor-vehicle accident	0.006	0.994	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.000	0.994	0.006
Q74 Other congenital malformations of limb(s)	0.000	0.994	0.006
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.994	0.006
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.000	0.994	0.006
Q66 Congenital deformities of feet	0.000	0.994	0.006
Q76.5 Cervical rib	0.000	0.994	0.006
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.006	0.994	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.000	0.994	0.006
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.994	0.006
K59 Other functional intestinal disorders	0.006	0.994	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.994	0.006
Q65 Congenital deformities of hip	0.000	0.994	0.006
Q63.8 Other specified congenital malformations of kidney	0.000	0.994	0.006
Q63.3 Hyperplastic and giant kidney	0.000	0.994	0.006
Q68 Other congenital musculoskeletal deformities	0.000	0.994	0.006
Y85 Sequelae of transport accidents	0.006	0.994	0.000
D41.2 Ureter	0.000	0.994	0.006
Q61.2 Polycystic kidney, adult type	0.000	0.994	0.006
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.000	0.994	0.005
Q70 Syndactyly	0.000	0.994	0.005
Q76.9 Congenital malformation of bony thorax, unspecified	0.000	0.994	0.005
Q76.8 Other congenital malformations of bony thorax	0.000	0.994	0.005
Q76.7 Congenital malformation of sternum	0.000	0.994	0.005
Q76.6 Other congenital malformations of ribs	0.000	0.994	0.005
Q76.3 Congenital scoliosis due to congenital bony malformation	0.000	0.994	0.005
Q76.2 Congenital spondylolisthesis	0.000	0.994	0.005
Q73 Reduction defects of unspecified limb	0.000	0.994	0.005
Q72 Reduction defects of lower limb	0.000	0.994	0.005
Q71 Reduction defects of upper limb	0.000	0.994	0.005
Q69 Polydactyly	0.000	0.994	0.005
I31.3 Pericardial effusion (noninflammatory)	0.005	0.995	0.000
Q07 Other congenital malformations of nervous system	0.000	0.995	0.005
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.000	0.995	0.005
Q76.0 Spina bifida occulta	0.000	0.995	0.005
Q66.3 Other congenital varus deformities of feet	0.000	0.995	0.005
Q75 Other congenital malformations of skull and face bones	0.000	0.995	0.005
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.995	0.005
Q30-Q34 Congenital malformations of the respiratory system	0.000	0.995	0.005
Q76.1 Klippel-Feil syndrome	0.000	0.995	0.005
Q61.0 Congenital single renal cyst	0.000	0.995	0.005
Q05.7 Lumbar spina bifida without hydrocephalus	0.000	0.995	0.005
Q62.1 Atresia and stenosis of ureter	0.000	0.995	0.005
Q04 Other congenital malformations of brain	0.000	0.995	0.005
Q79.8 Other congenital malformations of musculoskeletal system	0.000	0.995	0.005
Q62.8 Other congenital malformations of ureter	0.000	0.995	0.005
Q78 Other osteochondrodysplasias	0.000	0.995	0.005
Q61.4 Renal dysplasia	0.000	0.995	0.005
Q61.3 Polycystic kidney, unspecified	0.000	0.995	0.005
Q05.4 Unspecified spina bifida with hydrocephalus	0.000	0.995	0.005
Q61.9 Cystic kidney disease, unspecified	0.000	0.995	0.005
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.000	0.995	0.005
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.005	0.995	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.000	0.995	0.005
Q05.6 Thoracic spina bifida without hydrocephalus	0.000	0.995	0.005
Q05.5 Cervical spina bifida without hydrocephalus	0.000	0.995	0.005
Q05.3 Sacral spina bifida with hydrocephalus	0.000	0.995	0.005
Q05.2 Lumbar spina bifida with hydrocephalus	0.000	0.995	0.005
Q05.1 Thoracic spina bifida with hydrocephalus	0.000	0.995	0.005
Q05.0 Cervical spina bifida with hydrocephalus	0.000	0.995	0.005
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.005	0.995	0.000
N21.0 Calculus in bladder	0.005	0.995	0.000
I69 Sequelae of cerebrovascular disease	0.005	0.995	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.995	0.005
Q62.6 Malposition of ureter	0.000	0.995	0.005
Q62.4 Agenesis of ureter	0.000	0.995	0.005
Q62.0 Congenital hydronephrosis	0.000	0.995	0.005
Q66.9 Congenital deformity of feet, unspecified	0.000	0.995	0.005
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.000	0.995	0.005
Q01 Encephalocele	0.000	0.995	0.005
Q00 Anencephaly and similar malformations	0.000	0.995	0.005
Q02 Microcephaly	0.000	0.995	0.005
Q03 Congenital hydrocephalus	0.000	0.995	0.005
Q35-Q37 Cleft lip and cleft palate	0.000	0.995	0.005
Q61.8 Other cystic kidney diseases	0.000	0.995	0.005
Q61.1 Polycystic kidney, infantile type	0.000	0.995	0.005
Q67.4 Other congenital deformities of skull, face and jaw	0.000	0.995	0.005
D41.1 Renal pelvis	0.000	0.995	0.005
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.995	0.005
Z50.5 Speech therapy	0.005	0.995	0.000
Q12 Congenital lens malformations	0.000	0.995	0.005
K59.9 Functional intestinal disorder, unspecified	0.005	0.995	0.000
Q06 Other congenital malformations of spinal cord	0.000	0.995	0.005
E10-E14 Diabetes mellitus	0.000	0.995	0.005
Q64 Other congenital malformations of urinary system	0.000	0.995	0.005
D41.0 Kidney	0.000	0.995	0.005
Q31 Congenital malformations of larynx	0.000	0.995	0.005
D41.9 Urinary organ, unspecified	0.000	0.995	0.005
D41.7 Other urinary organs	0.000	0.995	0.005
D41.3 Urethra	0.000	0.995	0.005
Q62.2 Congenital megaloureter	0.000	0.995	0.004
Q67.6 Pectus excavatum	0.000	0.995	0.005
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.005	0.995	0.000
Q60.3 Renal hypoplasia, unilateral	0.000	0.995	0.005
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.000	0.995	0.005
Q74.9 Unspecified congenital malformation of limb(s)	0.000	0.995	0.004
Q74.8 Other specified congenital malformations of limb(s)	0.000	0.995	0.004
Q74.3 Arthrogryposis multiplex congenita	0.000	0.995	0.004
Y89 Sequelae of other external causes	0.005	0.995	0.000
H74.4 Polyp of middle ear	0.005	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.000	0.995	0.004
Q65.2 Congenital dislocation of hip, unspecified	0.000	0.995	0.004
Q65.8 Other congenital deformities of hip	0.000	0.995	0.004
C90.2 Plasmacytoma, extramedullary	0.000	0.995	0.004
Q07.8 Other specified congenital malformations of nervous system	0.000	0.995	0.004
Q68.8 Other specified congenital musculoskeletal deformities	0.000	0.995	0.004
I69.0 Sequelae of subarachnoid haemorrhage	0.004	0.995	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.995	0.004
Q66.5 Congenital pes planus	0.000	0.995	0.004
Q66.4 Talipes calcaneovalgus	0.000	0.995	0.004
Q66.2 Metatarsus varus	0.000	0.995	0.004
Q66.1 Talipes calcaneovarus	0.000	0.995	0.004
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.000	0.995	0.004
Q79.5 Other congenital malformations of abdominal wall	0.000	0.995	0.004
Q79.4 Prune belly syndrome	0.000	0.995	0.004
Q79.3 Gastroschisis	0.000	0.995	0.004
Q79.2 Exomphalos	0.000	0.995	0.004
Q66.0 Talipes equinovarus	0.000	0.996	0.004
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.004	0.996	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.004	0.996	0.000
Q12.0 Congenital cataract	0.000	0.996	0.004
Q74.1 Congenital malformation of knee	0.000	0.996	0.004
Q79.1 Other congenital malformations of diaphragm	0.000	0.996	0.004
Q07.0 Arnold-Chiari syndrome	0.000	0.996	0.004
Q67.8 Other congenital deformities of chest	0.000	0.996	0.004
Q67.7 Pectus carinatum	0.000	0.996	0.004
Q67.3 Plagiocephaly	0.000	0.996	0.004
Q67.2 Dolichocephaly	0.000	0.996	0.004
Q67.1 Compression facies	0.000	0.996	0.004
Q67.0 Facial asymmetry	0.000	0.996	0.004
Q77.4 Achondroplasia	0.000	0.996	0.004
Q04.6 Congenital cerebral cysts	0.000	0.996	0.004
Q18 Other congenital malformations of face and neck	0.000	0.996	0.004
Q65.0 Congenital dislocation of hip, unilateral	0.000	0.996	0.004
Q79.0 Congenital diaphragmatic hernia	0.000	0.996	0.004
K10 Other diseases of jaws	0.000	0.996	0.004
Q60.6 Potter's syndrome	0.000	0.996	0.004
Q60.5 Renal hypoplasia, unspecified	0.000	0.996	0.004
Q60.4 Renal hypoplasia, bilateral	0.000	0.996	0.004
Q60.1 Renal agenesis, bilateral	0.000	0.996	0.004
Q65.9 Congenital deformity of hip, unspecified	0.000	0.996	0.004
Q65.6 Unstable hip	0.000	0.996	0.004
Q65.5 Congenital subluxation of hip, unspecified	0.000	0.996	0.004
Q65.4 Congenital subluxation of hip, bilateral	0.000	0.996	0.004
Q65.3 Congenital subluxation of hip, unilateral	0.000	0.996	0.004
Q60.2 Renal agenesis, unspecified	0.000	0.996	0.004
Q31.0 Web of larynx	0.000	0.996	0.004
Q68.5 Congenital bowing of long bones of leg, unspecified	0.000	0.996	0.004
Q68.4 Congenital bowing of tibia and fibula	0.000	0.996	0.004
Q68.3 Congenital bowing of femur	0.000	0.996	0.004
Q68.2 Congenital deformity of knee	0.000	0.996	0.004
Q68.1 Congenital deformity of hand	0.000	0.996	0.004
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.000	0.996	0.004
Q70.3 Webbed toes	0.000	0.996	0.004
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.000	0.996	0.004
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.000	0.996	0.004
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.000	0.996	0.004
Q77.7 Spondyloepiphyseal dysplasia	0.000	0.996	0.004
Q77.6 Chondroectodermal dysplasia	0.000	0.996	0.004
Q77.5 Diastrophic dysplasia	0.000	0.996	0.004
Q77.3 Chondrodysplasia punctata	0.000	0.996	0.004
Q77.2 Short rib syndrome	0.000	0.996	0.004
Q77.1 Thanatophoric short stature	0.000	0.996	0.004
Q77.0 Achondrogenesis	0.000	0.996	0.004
K59.4 Anal spasm	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.996	0.004
Q70.9 Syndactyly, unspecified	0.000	0.996	0.004
Q70.4 Polysyndactyly	0.000	0.996	0.004
Q70.2 Fused toes	0.000	0.996	0.004
Q70.1 Webbed fingers	0.000	0.996	0.004
Q70.0 Fused fingers	0.000	0.996	0.004
C90.1 Plasma cell leukaemia	0.000	0.996	0.004
J44.8 Other specified chronic obstructive pulmonary disease	0.004	0.996	0.000
I69.3 Sequelae of cerebral infarction	0.004	0.996	0.000
Q69.9 Polydactyly, unspecified	0.000	0.996	0.004
Q69.2 Accessory toe(s)	0.000	0.996	0.004
Q69.1 Accessory thumb(s)	0.000	0.996	0.004
Q69.0 Accessory finger(s)	0.000	0.996	0.004
Q71.9 Reduction defect of upper limb, unspecified	0.000	0.996	0.004
Q71.8 Other reduction defects of upper limb(s)	0.000	0.996	0.004
Q71.6 Lobster-claw hand	0.000	0.996	0.004
Q71.5 Longitudinal reduction defect of ulna	0.000	0.996	0.004
Q71.4 Longitudinal reduction defect of radius	0.000	0.996	0.004
Q71.3 Congenital absence of hand and finger(s)	0.000	0.996	0.004
Q71.2 Congenital absence of both forearm and hand	0.000	0.996	0.004
Q71.1 Congenital absence of upper arm and forearm with hand present	0.000	0.996	0.004
Q71.0 Congenital complete absence of upper limb(s)	0.000	0.996	0.004
Q72.9 Reduction defect of lower limb, unspecified	0.000	0.996	0.004
Q72.8 Other reduction defects of lower limb(s)	0.000	0.996	0.004
Q72.7 Split foot	0.000	0.996	0.004
Q72.6 Longitudinal reduction defect of fibula	0.000	0.996	0.004
Q72.5 Longitudinal reduction defect of tibia	0.000	0.996	0.004
Q72.4 Longitudinal reduction defect of femur	0.000	0.996	0.004
Q72.3 Congenital absence of foot and toe(s)	0.000	0.996	0.004
Q72.2 Congenital absence of both lower leg and foot	0.000	0.996	0.004
Q72.1 Congenital absence of thigh and lower leg with foot present	0.000	0.996	0.004
Q72.0 Congenital complete absence of lower limb(s)	0.000	0.996	0.004
Q73.8 Other reduction defects of unspecified limb(s)	0.000	0.996	0.004
Q73.1 Phocomelia, unspecified limb(s)	0.000	0.996	0.004
Q73.0 Congenital absence of unspecified limb(s)	0.000	0.996	0.004
Q07.9 Congenital malformation of nervous system, unspecified	0.000	0.996	0.004
Q13 Congenital malformations of anterior segment of eye	0.000	0.996	0.004
F60.9 Personality disorder, unspecified	0.000	0.996	0.004
Q65.1 Congenital dislocation of hip, bilateral	0.000	0.996	0.004
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.000	0.996	0.004
Q79.6 Ehlers-Danlos syndrome	0.000	0.996	0.004
C90.3 Solitary plasmacytoma	0.000	0.996	0.004
Q75.9 Congenital malformation of skull and face bones, unspecified	0.000	0.996	0.004
Q75.8 Other specified congenital malformations of skull and face bones	0.000	0.996	0.004
Q75.5 Oculomandibular dysostosis	0.000	0.996	0.004
Q75.3 Macrocephaly	0.000	0.996	0.004
Q75.2 Hypertelorism	0.000	0.996	0.004
Q75.1 Craniofacial dysostosis	0.000	0.996	0.004
Q75.0 Craniosynostosis	0.000	0.996	0.004
Q30 Congenital malformations of nose	0.000	0.996	0.004
K59.2 Neurogenic bowel, not elsewhere classified	0.004	0.996	0.000
Q66.7 Pes cavus	0.000	0.996	0.004
Q16 Congenital malformations of ear causing impairment of hearing	0.000	0.996	0.004
Q34 Other congenital malformations of respiratory system	0.000	0.996	0.004
Q33 Congenital malformations of lung	0.000	0.996	0.004
Q32 Congenital malformations of trachea and bronchus	0.000	0.996	0.004
Z50 Care involving use of rehabilitation procedures	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.000	0.996	0.004
Q10.0 Congenital ptosis	0.000	0.996	0.004
Q17 Other congenital malformations of ear	0.000	0.996	0.004
Q14 Congenital malformations of posterior segment of eye	0.000	0.996	0.004
Y88 Sequelae of surgical and medical care as external cause	0.004	0.996	0.000
Q04.9 Congenital malformation of brain, unspecified	0.000	0.996	0.004
Q04.5 Megalencephaly	0.000	0.996	0.004
Q04.4 Septo-optic dysplasia	0.000	0.996	0.004
Q04.3 Other reduction deformities of brain	0.000	0.996	0.004
Q04.2 Holoprosencephaly	0.000	0.996	0.004
Q04.1 Arhinencephaly	0.000	0.996	0.004
Q04.0 Congenital malformations of corpus callosum	0.000	0.996	0.004
Q15 Other congenital malformations of eye	0.000	0.996	0.004
Q35 Cleft palate	0.000	0.996	0.004
Q75.4 Mandibulofacial dysostosis	0.000	0.996	0.004
Q04.8 Other specified congenital malformations of brain	0.000	0.996	0.004
Q78.9 Osteochondrodysplasia, unspecified	0.000	0.996	0.004
Q78.8 Other specified osteochondrodysplasias	0.000	0.996	0.004
Q78.6 Multiple congenital exostoses	0.000	0.996	0.004
Q78.5 Metaphyseal dysplasia	0.000	0.996	0.004
Q78.4 Enchondromatosis	0.000	0.996	0.004
Q78.3 Progressive diaphyseal dysplasia	0.000	0.996	0.004
Q78.1 Polyostotic fibrous dysplasia	0.000	0.996	0.004
Q78.0 Osteogenesis imperfecta	0.000	0.996	0.004
K10.8 Other specified diseases of jaws	0.000	0.996	0.004
Q61.5 Medullary cystic kidney	0.000	0.996	0.004
Q67.5 Congenital deformity of spine	0.000	0.996	0.004
Y87.2 Sequelae of events of undetermined intent	0.004	0.996	0.000
K10.3 Alveolitis of jaws	0.000	0.996	0.004
Q00.2 Iniencephaly	0.000	0.996	0.004
Q00.1 Craniorachischisis	0.000	0.996	0.004
Q00.0 Anencephaly	0.000	0.996	0.004
Q01.9 Encephalocele, unspecified	0.000	0.996	0.004
Q01.8 Encephalocele of other sites	0.000	0.996	0.004
Q01.2 Occipital encephalocele	0.000	0.996	0.004
Q01.1 Nasofrontal encephalocele	0.000	0.996	0.004
Q01.0 Frontal encephalocele	0.000	0.996	0.004
Q03.9 Congenital hydrocephalus, unspecified	0.000	0.996	0.004
Q03.8 Other congenital hydrocephalus	0.000	0.996	0.004
Q03.1 Atresia of foramina of Magendie and Luschka	0.000	0.996	0.004
Q31.3 Laryngocele	0.000	0.996	0.004
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.004	0.996	0.000
Q36 Cleft lip	0.000	0.996	0.004
Q03.0 Malformations of aqueduct of Sylvius	0.000	0.996	0.004
Q37 Cleft palate with cleft lip	0.000	0.996	0.004
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.004	0.996	0.000
Q12.9 Congenital lens malformation, unspecified	0.000	0.996	0.004
Q12.8 Other congenital lens malformations	0.000	0.996	0.004
Q12.4 Spherophakia	0.000	0.996	0.004
Q12.3 Congenital aphakia	0.000	0.996	0.004
Q12.2 Coloboma of lens	0.000	0.996	0.004
Q12.1 Congenital displaced lens	0.000	0.996	0.004
F60 Specific personality disorders	0.000	0.996	0.004
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.996	0.003
E12 Malnutrition-related diabetes mellitus	0.000	0.996	0.004
K59.8 Other specified functional intestinal disorders	0.004	0.996	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.000	0.996	0.003
Q06.4 Hydromyelia	0.000	0.996	0.003
Q06.3 Other congenital cauda equina malformations	0.000	0.996	0.003
Q06.2 Diastematomyelia	0.000	0.996	0.003
Q06.1 Hypoplasia and dysplasia of spinal cord	0.000	0.996	0.003
Q06.0 Amyelia	0.000	0.996	0.003
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.996	0.003
Q64.8 Other specified congenital malformations of urinary system	0.000	0.996	0.003
Q64.6 Congenital diverticulum of bladder	0.000	0.996	0.003
Q64.5 Congenital absence of bladder and urethra	0.000	0.996	0.003
Q64.2 Congenital posterior urethral valves	0.000	0.996	0.003
Q64.1 Exstrophy of urinary bladder	0.000	0.996	0.003
Q64.0 Epispadias	0.000	0.996	0.003
Y89.9 Sequelae of unspecified external cause	0.004	0.996	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.004	0.996	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.000	0.996	0.003
Q31.8 Other congenital malformations of larynx	0.000	0.996	0.003
Q31.5 Congenital laryngomalacia	0.000	0.996	0.003
Q31.4 Congenital laryngeal stridor	0.000	0.996	0.003
Q31.2 Laryngeal hypoplasia	0.000	0.996	0.003
Q31.1 Congenital subglottic stenosis	0.000	0.996	0.003
Q53 Undescended testicle	0.000	0.996	0.004
Q18.1 Preauricular sinus and cyst	0.000	0.996	0.004
Q64.4 Malformation of urachus	0.000	0.996	0.003
Y87.1 Sequelae of assault	0.003	0.996	0.000
Z50.2 Alcohol rehabilitation	0.004	0.996	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.004	0.996	0.000
Q10.7 Congenital malformation of orbit	0.000	0.996	0.003
Q10.6 Other congenital malformations of lachrymal apparatus	0.000	0.996	0.003
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.000	0.996	0.003
Q10.4 Absence and agenesis of lachrymal apparatus	0.000	0.996	0.003
Q10.3 Other congenital malformations of eyelid	0.000	0.996	0.003
Q10.2 Congenital entropion	0.000	0.996	0.003
Q10.1 Congenital ectropion	0.000	0.996	0.003
Q78.2 Osteopetrosis	0.000	0.996	0.003
Z50.4 Psychotherapy, not elsewhere classified	0.004	0.996	0.000
Y87.0 Sequelae of intentional self-harm	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations