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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129860
log Bayes Factor = 212.976
Chromosome 6   position 32,401,079  (GRCh37) Explore rs3129860 on Ensembl!
Variant rs3129860 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
J45 Asthma
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
I10-I15 Hypertensive diseases
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.001 0.001
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
K70-K77 Diseases of liver
0.000 0.002 0.998
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
J33 Nasal polyp
0.000 0.003 0.997
J33.9 Nasal polyp, unspecified
0.000 0.003 0.997
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.003 0.997
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
E14.3 With ophthalmic complications
0.000 0.005 0.995
I10 Essential (primary) hypertension
0.000 0.006 0.994
K51.3 Ulcerative (chronic) rectosigmoiditis
0.994 0.006 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
H43-H45 Disorders of vitreous body and globe
0.000 0.008 0.992
H40-H42 Glaucoma
0.000 0.010 0.990
E70-E90 Metabolic disorders
0.000 0.010 0.990
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.011 0.989
H43 Disorders of vitreous body
0.000 0.011 0.989
K74 Fibrosis and cirrhosis of liver
0.000 0.012 0.988
L40-L45 Papulosquamous disorders
0.000 0.015 0.985
J30-J39 Other diseases of upper respiratory tract
0.000 0.015 0.985
H40 Glaucoma
0.000 0.016 0.984
L43 Lichen planus
0.000 0.017 0.983
L40 Psoriasis
0.000 0.018 0.982
L43.9 Lichen planus, unspecified
0.000 0.018 0.982
H40.9 Glaucoma, unspecified
0.000 0.019 0.981
I22 Subsequent myocardial infarction
0.000 0.019 0.981
E10.5 With peripheral circulatory complications
0.000 0.020 0.980
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.021 0.979
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.022 0.978
I20 Angina pectoris
0.000 0.023 0.977
E11.3 With ophthalmic complications
0.000 0.025 0.975
L40.5 Arthropathic psoriasis
0.000 0.027 0.973
J33.8 Other polyp of sinus
0.000 0.027 0.973
I25 Chronic ischaemic heart disease
0.000 0.027 0.973
E06 Thyroiditis
0.000 0.030 0.970
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.031 0.969
H43.3 Other vitreous opacities
0.000 0.034 0.966
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.034 0.965
K74.3 Primary biliary cirrhosis
0.000 0.035 0.965
E05.9 Thyrotoxicosis, unspecified
0.000 0.035 0.965
K51.8 Other ulcerative colitis
0.961 0.039 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.041 0.959
Chapter VIII Diseases of the ear and mastoid process
0.000 0.042 0.958
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.043 0.957
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.044 0.956
J44 Other chronic obstructive pulmonary disease
0.000 0.048 0.952
E11.1 With ketoacidosis
0.000 0.048 0.952
H60-H62 Diseases of external ear
0.000 0.049 0.951
H43.8 Other disorders of vitreous body
0.000 0.050 0.950
E06.3 Autoimmune thyroiditis
0.000 0.051 0.949
K50-K52 Noninfective enteritis and colitis
0.014 0.056 0.930
H61 Other disorders of external ear
0.000 0.057 0.943
J33.0 Polyp of nasal cavity
0.000 0.060 0.940
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.063 0.937
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.065 0.935
E10.2 With renal complications
0.000 0.068 0.932
K82 Other diseases of gallbladder
0.000 0.070 0.930
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.073 0.927
J46 Status asthmaticus
0.000 0.075 0.925
K82.8 Other specified diseases of gallbladder
0.000 0.077 0.923
H34 Retinal vascular occlusions
0.000 0.079 0.921
E11.5 With peripheral circulatory complications
0.000 0.081 0.919
K72 Hepatic failure, not elsewhere classified
0.000 0.082 0.918
H61.0 Perichondritis of external ear
0.000 0.082 0.918
M06.0 Seronegative rheumatoid arthritis
0.000 0.082 0.918
I25.5 Ischaemic cardiomyopathy
0.000 0.085 0.915
K55-K64 Other diseases of intestines
0.000 0.086 0.914
I20.1 Angina pectoris with documented spasm
0.000 0.090 0.910
I12 Hypertensive renal disease
0.000 0.090 0.910
I24 Other acute ischaemic heart diseases
0.000 0.092 0.908
K60 Fissure and fistula of anal and rectal regions
0.000 0.093 0.907
K51.2 Ulcerative (chronic) proctitis
0.907 0.093 0.000
I20.9 Angina pectoris, unspecified
0.000 0.093 0.907
E11.2 With renal complications
0.000 0.098 0.902
L40.9 Psoriasis, unspecified
0.000 0.101 0.899
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.102 0.898
J86 Pyothorax
0.000 0.104 0.896
E07 Other disorders of thyroid
0.000 0.105 0.895
I25.2 Old myocardial infarction
0.000 0.106 0.894
M07 Psoriatic and enteropathic arthropathies
0.000 0.106 0.894
I20.0 Unstable angina
0.000 0.107 0.893
E03.8 Other specified hypothyroidism
0.000 0.112 0.887
K75 Other inflammatory liver diseases
0.000 0.113 0.887
K60.2 Anal fissure, unspecified
0.000 0.114 0.886
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.117 0.883
K50 Crohn's disease [regional enteritis]
0.001 0.128 0.872
E13 Other specified diabetes mellitus
0.000 0.129 0.871
K58 Irritable bowel syndrome
0.000 0.133 0.867
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.133 0.867
K74.6 Other and unspecified cirrhosis of liver
0.000 0.133 0.867
E11.6 With other specified complications
0.000 0.136 0.864
H40.1 Primary open-angle glaucoma
0.000 0.139 0.861
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.144 0.856
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.147 0.853
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.148 0.852
J43 Emphysema
0.000 0.149 0.851
K60.0 Acute anal fissure
0.000 0.151 0.849
I15 Secondary hypertension
0.000 0.152 0.848
K75.4 Autoimmune hepatitis
0.000 0.154 0.846
M65-M68 Disorders of synovium and tendon
0.000 0.161 0.839
J86.9 Pyothorax without fistula
0.000 0.161 0.839
M06.4 Inflammatory polyarthropathy
0.000 0.161 0.839
I35.0 Aortic (valve) stenosis
0.000 0.163 0.837
K74.5 Biliary cirrhosis, unspecified
0.000 0.164 0.836
H40.5 Glaucoma secondary to other eye disorders
0.000 0.166 0.834
E07.9 Disorder of thyroid, unspecified
0.000 0.168 0.832
K73 Chronic hepatitis, not elsewhere classified
0.000 0.168 0.831
G37.8 Other specified demyelinating diseases of central nervous system
0.829 0.171 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.172 0.828
K60.5 Anorectal fistula
0.000 0.175 0.825
I25.1 Atherosclerotic heart disease
0.000 0.178 0.822
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.822 0.178 0.000
M06.3 Rheumatoid nodule
0.000 0.178 0.822
I12.9 Hypertensive renal disease without renal failure
0.000 0.179 0.821
K82.1 Hydrops of gallbladder
0.000 0.182 0.818
M07.3 Other psoriatic arthropathies
0.000 0.182 0.818
K72.9 Hepatic failure, unspecified
0.000 0.183 0.817
H61.1 Non-infective disorders of pinna
0.000 0.186 0.814
E88 Other metabolic disorders
0.000 0.187 0.813
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.189 0.811
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.191 0.809
E78.1 Pure hyperglyceridaemia
0.000 0.198 0.802
H60 Otitis externa
0.000 0.202 0.798
K86 Other diseases of pancreas
0.000 0.204 0.796
H34.8 Other retinal vascular occlusions
0.000 0.205 0.795
L43.8 Other lichen planus
0.000 0.207 0.793
M14 Arthropathies in other diseases classified elsewhere
0.000 0.210 0.790
H34.2 Other retinal artery occlusions
0.000 0.210 0.790
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.210 0.790
E78.5 Hyperlipidaemia, unspecified
0.000 0.210 0.790
E16.1 Other hypoglycaemia
0.000 0.211 0.789
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.212 0.788
K50.8 Other Crohn's disease
0.000 0.212 0.788
H61.8 Other specified disorders of external ear
0.000 0.214 0.786
K50.1 Crohn's disease of large intestine
0.000 0.216 0.784
E40-E46 Malnutrition
0.000 0.218 0.782
E78.2 Mixed hyperlipidaemia
0.000 0.219 0.781
J37 Chronic laryngitis and laryngotracheitis
0.000 0.221 0.779
K51.5 Mucosal proctocolitis
0.779 0.221 0.000
K63 Other diseases of intestine
0.000 0.221 0.779
E13.9 Without complications
0.000 0.221 0.779
I35 Nonrheumatic aortic valve disorders
0.000 0.222 0.778
M65 Synovitis and tenosynovitis
0.000 0.225 0.775
K72.0 Acute and subacute hepatic failure
0.000 0.227 0.773
H43.1 Vitreous haemorrhage
0.000 0.228 0.772
J86.0 Pyothorax with fistula
0.000 0.229 0.771
K51.4 Pseudopolyposis of colon
0.770 0.230 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.231 0.769
H61.3 Acquired stenosis of external ear canal
0.000 0.234 0.766
K63.9 Disease of intestine, unspecified
0.000 0.235 0.765
K55 Vascular disorders of intestine
0.000 0.236 0.764
J32 Chronic sinusitis
0.000 0.239 0.761
K52 Other non-infective gastro-enteritis and colitis
0.003 0.247 0.750
H43.2 Crystalline deposits in vitreous body
0.000 0.248 0.751
I23 Certain current complications following acute myocardial infarction
0.000 0.249 0.751
K90.9 Intestinal malabsorption, unspecified
0.000 0.250 0.750
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.251 0.749
H25-H28 Disorders of lens
0.000 0.252 0.748
J95-J99 Other diseases of the respiratory system
0.000 0.252 0.748
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.257 0.743
E11.8 With unspecified complications
0.000 0.258 0.742
E74 Other disorders of carbohydrate metabolism
0.000 0.260 0.740
I30-I52 Other forms of heart disease
0.000 0.263 0.737
M11 Other crystal arthropathies
0.000 0.266 0.734
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.266 0.734
I11 Hypertensive heart disease
0.000 0.267 0.733
H40.4 Glaucoma secondary to eye inflammation
0.000 0.269 0.731
M70-M79 Other soft tissue disorders
0.000 0.270 0.730
L40.8 Other psoriasis
0.000 0.273 0.727
I12.0 Hypertensive renal disease with renal failure
0.000 0.276 0.724
I25.4 Coronary artery aneurysm
0.000 0.279 0.721
L40.0 Psoriasis vulgaris
0.000 0.280 0.720
E11.4 With neurological complications
0.000 0.280 0.720
E11.0 With coma
0.000 0.281 0.719
H30 Chorioretinal inflammation
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
I21 Acute myocardial infarction
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.716
J45.1 Nonallergic asthma
0.000 0.283 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
I13 Hypertensive heart and renal disease
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.001
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.000 0.285 0.715
K71 Toxic liver disease
0.000 0.285 0.715
K86.2 Cyst of pancreas
0.000 0.285 0.715
J33.1 Polypoid sinus degeneration
0.000 0.285 0.715
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.287 0.713
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.287 0.713
H43.9 Disorder of vitreous body, unspecified
0.000 0.288 0.712
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
Chapter VI Diseases of the nervous system
0.019 0.289 0.693
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.289 0.711
H42 Glaucoma in diseases classified elsewhere
0.000 0.290 0.710
E77 Disorders of glycoprotein metabolism
0.000 0.290 0.710
E76 Disorders of glycosaminoglycan metabolism
0.000 0.290 0.710
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.290 0.710
E72 Other disorders of amino-acid metabolism
0.000 0.290 0.710
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.290 0.710
E70 Disorders of aromatic amino-acid metabolism
0.000 0.290 0.710
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.290 0.710
H43.0 Vitreous prolapse
0.000 0.291 0.709
K74.4 Secondary biliary cirrhosis
0.000 0.291 0.708
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.291 0.708
K74.1 Hepatic sclerosis
0.000 0.291 0.708
L44 Other papulosquamous disorders
0.000 0.294 0.706
L41 Parapsoriasis
0.000 0.294 0.706
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.294 0.706
K81 Cholecystitis
0.000 0.294 0.706
H40.6 Glaucoma secondary to drugs
0.000 0.295 0.705
H40.3 Glaucoma secondary to eye trauma
0.000 0.295 0.705
L43.3 Subacute (active) lichen planus
0.000 0.295 0.705
L43.2 Lichenoid drug reaction
0.000 0.295 0.705
L43.1 Bullous lichen planus
0.000 0.295 0.705
L43.0 Hypertrophic lichen planus
0.000 0.295 0.705
H34.1 Central retinal artery occlusion
0.000 0.296 0.704
L40.4 Guttate psoriasis
0.000 0.296 0.704
L40.3 Pustulosis palmaris et plantaris
0.000 0.296 0.704
L40.2 Acrodermatitis continua
0.000 0.296 0.704
L40.1 Generalised pustular psoriasis
0.000 0.296 0.704
E05.5 Thyroid crisis or storm
0.000 0.299 0.701
E05.4 Thyrotoxicosis factitia
0.000 0.299 0.701
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.299 0.701
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.299 0.701
J43.9 Emphysema, unspecified
0.000 0.299 0.701
I15.1 Hypertension secondary to other renal disorders
0.000 0.300 0.700
I46 Cardiac arrest
0.000 0.302 0.698
I25.6 Silent myocardial ischaemia
0.000 0.302 0.697
K82.9 Disease of gallbladder, unspecified
0.000 0.303 0.697
J41 Simple and mucopurulent chronic bronchitis
0.000 0.303 0.697
G50-G59 Nerve, nerve root and plexus disorders
0.002 0.304 0.694
E06.5 Other chronic thyroiditis
0.000 0.304 0.695
E06.4 Drug-induced thyroiditis
0.000 0.304 0.695
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.304 0.695
E06.1 Subacute thyroiditis
0.000 0.304 0.695
E06.0 Acute thyroiditis
0.000 0.304 0.695
K51.0 Ulcerative (chronic) enterocolitis
0.695 0.305 0.000
K82.2 Perforation of gallbladder
0.000 0.305 0.694
G56.0 Carpal tunnel syndrome
0.000 0.306 0.694
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.310 0.690
G56 Mononeuropathies of upper limb
0.000 0.310 0.690
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.312 0.688
M12 Other specific arthropathies
0.000 0.312 0.688
K82.3 Fistula of gallbladder
0.000 0.313 0.687
E06.9 Thyroiditis, unspecified
0.000 0.313 0.686
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.315 0.685
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.315 0.685
H27 Other disorders of lens
0.000 0.316 0.684
M45-M49 Spondylopathies
0.000 0.316 0.684
M14.6 Neuropathic arthropathy
0.000 0.316 0.684
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.316 0.684
K52.1 Toxic gastro-enteritis and colitis
0.001 0.318 0.681
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.318 0.682
G59 Mononeuropathy in diseases classified elsewhere
0.001 0.318 0.681
H60.9 Otitis externa, unspecified
0.000 0.318 0.682
I46.9 Cardiac arrest, unspecified
0.000 0.319 0.681
K73.9 Chronic hepatitis, unspecified
0.000 0.320 0.680
J43.2 Centrilobular emphysema
0.000 0.321 0.679
M06.34 Rheumatoid nodule (Hand)
0.000 0.324 0.676
K86.3 Pseudocyst of pancreas
0.000 0.325 0.675
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.326 0.673
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.327 0.673
G59.0 Diabetic mononeuropathy
0.000 0.327 0.673
E83 Disorders of mineral metabolism
0.507 0.328 0.165
I15.9 Seconday hypertension, unspecified
0.000 0.328 0.672
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.328 0.672
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.330 0.670
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.330 0.670
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.330 0.669
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.331 0.669
M45 Ankylosing spondylitis
0.000 0.331 0.669
I25.3 Aneurysm of heart
0.000 0.334 0.666
E84 Cystic fibrosis
0.000 0.338 0.662
M77 Other enthesopathies
0.000 0.339 0.661
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.339 0.661
H34.0 Transient retinal artery occlusion
0.000 0.339 0.661
K72.1 Chronic hepatic failure
0.000 0.341 0.658
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.342 0.658
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.342 0.658
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.342 0.658
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.342 0.658
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.342 0.658
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.342 0.658
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.342 0.658
K75.9 Inflammatory liver disease, unspecified
0.000 0.342 0.658
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.342 0.658
H61.9 Disorder of external ear, unspecified
0.000 0.343 0.656
K63.4 Enteroptosis
0.000 0.344 0.656
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.344 0.655
I35.8 Other aortic valve disorders
0.000 0.347 0.653
L42 Pityriasis rosea
0.000 0.347 0.653
K55.2 Angiodysplasia of colon
0.000 0.347 0.653
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.348 0.652
M77.1 Lateral epicondylitis
0.000 0.349 0.651
E05.8 Other thyrotoxicosis
0.000 0.350 0.650
E78.8 Other disorders of lipoprotein metabolism
0.000 0.351 0.649
K55.8 Other vascular disorders of intestine
0.000 0.351 0.649
H34.9 Retinal vascular occlusion, unspecified
0.000 0.352 0.647
H65-H75 Diseases of middle ear and mastoid
0.000 0.352 0.648
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.353 0.647
K63.3 Ulcer of intestine
0.000 0.353 0.647
K74.0 Hepatic fibrosis
0.000 0.353 0.647
K50.0 Crohn's disease of small intestine
0.000 0.353 0.646
I21.4 Acute subendocardial myocardial infarction
0.000 0.354 0.646
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.354 0.645
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.003 0.355 0.643
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.355 0.645
J42 Unspecified chronic bronchitis
0.000 0.356 0.644
E07.1 Dyshormogenetic goitre
0.000 0.358 0.642
E07.0 Hypersecretion of calcitonin
0.000 0.358 0.642
M75 Shoulder lesions
0.000 0.358 0.642
M07.6 Other enteropathic arthropathies
0.000 0.359 0.641
M07.5 Arthropathy in ulcerative colitis
0.000 0.359 0.641
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.359 0.641
M07.2 Psoriatic spondylitis
0.000 0.359 0.641
M07.1 Arthritis mutilans
0.000 0.359 0.641
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.359 0.641
E79 Disorders of purine and pyrimidine metabolism
0.000 0.360 0.639
J32.4 Chronic pansinusitis
0.000 0.360 0.640
K86.1 Other chronic pancreatitis
0.000 0.361 0.639
K81.1 Chronic cholecystitis
0.000 0.364 0.636
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.364 0.636
K82.0 Obstruction of gallbladder
0.000 0.364 0.636
K75.2 Nonspecific reactive hepatitis
0.000 0.364 0.636
K75.1 Phlebitis of portal vein
0.000 0.364 0.636
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.366 0.634
J37.0 Chronic laryngitis
0.000 0.368 0.632
E88.2 Lipomatosis, not elsewhere classified
0.000 0.368 0.632
M10 Gout
0.000 0.372 0.628
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.372 0.628
J85 Abscess of lung and mediastinum
0.000 0.372 0.628
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.373 0.627
E46 Unspecified protein-energy malnutrition
0.000 0.374 0.626
E13.8 With unspecified complications
0.000 0.375 0.624
E13.7 With multiple complications
0.000 0.375 0.624
E13.6 With other specified complications
0.000 0.375 0.624
E13.5 With peripheral circulatory complications
0.000 0.375 0.624
E13.4 With neurological complications
0.000 0.375 0.624
E13.3 With ophthalmic complications
0.000 0.375 0.624
E13.2 With renal complications
0.000 0.375 0.624
E13.1 With ketoacidosis
0.000 0.375 0.624
E13.0 With coma
0.000 0.375 0.624
M75.0 Adhesive capsulitis of shoulder
0.000 0.380 0.620
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.382 0.618
J35 Chronic diseases of tonsils and adenoids
0.000 0.384 0.616
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.385 0.615
L10-L14 Bullous disorders
0.000 0.385 0.615
G51 Facial nerve disorders
0.000 0.385 0.614
H60.8 Other otitis externa
0.000 0.387 0.613
J43.8 Other emphysema
0.000 0.390 0.610
J43.1 Panlobular emphysema
0.000 0.390 0.610
J43.0 MacLeod's syndrome
0.000 0.390 0.610
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.390 0.610
I31 Other diseases of pericardium
0.000 0.391 0.609
J32.9 Chronic sinusitis, unspecified
0.000 0.392 0.608
I15.8 Other secondary hypertension
0.000 0.392 0.608
I15.2 Hypertension secondary to endocrine disorders
0.000 0.392 0.608
I15.0 Renovascular hypertension
0.000 0.392 0.608
H61.2 Impacted cerumen
0.000 0.394 0.606
K91.3 Postoperative intestinal obstruction
0.000 0.395 0.605
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.396 0.604
E73 Lactose intolerance
0.000 0.398 0.602
H60.5 Acute otitis externa, non-infective
0.000 0.398 0.602
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.398 0.602
J98 Other respiratory disorders
0.000 0.398 0.602
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.398 0.601
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.398 0.601
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.398 0.601
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.398 0.601
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.398 0.601
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.398 0.601
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.398 0.601
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.398 0.601
K52.8 Other specified non-infective gastro-enteritis and colitis
0.001 0.403 0.596
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.404 0.596
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.404 0.596
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.404 0.596
H27.0 Aphakia
0.000 0.404 0.596
E07.8 Other specified disorders of thyroid
0.000 0.406 0.594
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.409 0.591
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.411 0.589
M06.38 Rheumatoid nodule (Other)
0.000 0.411 0.589
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.411 0.589
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.411 0.589
M06.33 Rheumatoid nodule (Forearm)
0.000 0.411 0.589
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.411 0.589
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.411 0.589
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.411 0.589
K60.4 Rectal fistula
0.000 0.412 0.588
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.412 0.587
M07.38 Other psoriatic arthropathies (Other)
0.000 0.413 0.587
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.413 0.587
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.413 0.587
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.413 0.587
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.413 0.587
K90.8 Other intestinal malabsorption
0.000 0.415 0.584
K55.1 Chronic vascular disorders of intestine
0.000 0.417 0.583
E88.9 Metabolic disorder, unspecified
0.000 0.417 0.583

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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