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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129890
log Bayes Factor = 86.6135
Chromosome 6   position 32,414,273  (GRCh37) Explore rs3129890 on Ensembl!
Variant rs3129890 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E10.1 With ketoacidosis
1.000 0.000 0.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
D64 Other anaemias
0.999 0.001 0.000
D64.9 Anaemia, unspecified
0.999 0.001 0.000
Q60-Q64 Congenital malformations of the urinary system
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.996 0.004 0.000
D50 Iron deficiency anaemia
0.996 0.004 0.000
M15-M19 Arthrosis
0.996 0.004 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
D50.9 Iron deficiency anaemia, unspecified
0.994 0.006 0.000
H30-H36 Disorders of choroid and retina
0.994 0.006 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.994 0.006 0.000
H06.2 Dysthyroid exophthalmos
0.993 0.007 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.007 0.993
M18 Arthrosis of first carpometacarpal joint
0.991 0.009 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.990 0.010 0.000
Q61 Cystic kidney disease
0.989 0.011 0.000
M17.1 Other primary gonarthrosis
0.989 0.011 0.000
M17 Gonarthrosis [arthrosis of knee]
0.988 0.012 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.987 0.013 0.000
M06.3 Rheumatoid nodule
0.000 0.014 0.986
M35.0 Sicca syndrome [Sjogren]
0.983 0.017 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.983 0.017 0.000
E14.9 Without complications
0.983 0.017 0.000
E16 Other disorders of pancreatic internal secretion
0.982 0.018 0.000
I10-I15 Hypertensive diseases
0.979 0.021 0.000
M35 Other systemic involvement of connective tissue
0.978 0.022 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.978 0.022 0.000
M20-M25 Other joint disorders
0.977 0.023 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.976 0.024 0.000
I12 Hypertensive renal disease
0.975 0.025 0.000
D51 Vitamin B12 deficiency anaemia
0.975 0.025 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.026 0.974
E16.2 Hypoglycaemia, unspecified
0.974 0.026 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.972 0.028 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.972 0.028 0.000
H36 Retinal disorders in diseases classified elsewhere
0.972 0.028 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.036 0.964
I60-I69 Cerebrovascular diseases
0.963 0.037 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.963 0.037 0.000
I12.9 Hypertensive renal disease without renal failure
0.961 0.039 0.000
R31 Unspecified haematuria
0.000 0.042 0.958
E27 Other disorders of adrenal gland
0.957 0.043 0.000
H36.0 Diabetic retinopathy
0.956 0.044 0.000
E10.4 With neurological complications
0.956 0.044 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.955 0.045 0.000
N00-N08 Glomerular diseases
0.955 0.045 0.000
Q61.3 Polycystic kidney, unspecified
0.954 0.046 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.953 0.047 0.000
E21.3 Hyperparathyroidism, unspecified
0.952 0.048 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.048 0.952
H05 Disorders of orbit
0.952 0.048 0.000
D80-D89 Certain disorders involving the immune mechanism
0.951 0.049 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.951 0.049 0.000
D61 Other aplastic anaemias
0.950 0.050 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.949 0.051 0.000
E10.2 With renal complications
0.949 0.051 0.000
Q43 Other congenital malformations of intestine
0.947 0.053 0.000
E27.1 Primary adrenocortical insufficiency
0.947 0.053 0.000
I71 Aortic aneurysm and dissection
0.945 0.055 0.000
E14.3 With ophthalmic complications
0.945 0.055 0.000
E28 Ovarian dysfunction
0.943 0.057 0.000
N04 Nephrotic syndrome
0.941 0.059 0.000
Chapter VI Diseases of the nervous system
0.940 0.060 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.940 0.060 0.000
H00.1 Chalazion
0.000 0.061 0.939
M15 Polyarthrosis
0.935 0.065 0.000
E40-E46 Malnutrition
0.934 0.066 0.000
L40.9 Psoriasis, unspecified
0.000 0.066 0.934
G56 Mononeuropathies of upper limb
0.931 0.069 0.000
G56.0 Carpal tunnel syndrome
0.931 0.069 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.928 0.072 0.000
H35 Other retinal disorders
0.925 0.075 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.924 0.076 0.000
E07 Other disorders of thyroid
0.919 0.081 0.000
H33 Retinal detachments and breaks
0.918 0.082 0.000
N04.9 Unspecified
0.917 0.083 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.083 0.917
Q60.0 Renal agenesis, unilateral
0.916 0.084 0.000
D69 Purpura and other haemorrhagic conditions
0.916 0.084 0.000
Chapter XIV Diseases of the genitourinary system
0.913 0.087 0.000
Q60.2 Renal agenesis, unspecified
0.913 0.087 0.000
I12.0 Hypertensive renal disease with renal failure
0.911 0.089 0.000
H05.2 Exophthalmic conditions
0.911 0.089 0.000
M60-M63 Disorders of muscles
0.910 0.090 0.000
N05 Unspecified nephritic syndrome
0.909 0.091 0.000
M32 Systemic lupus erythematosus
0.907 0.093 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.095 0.905
I77 Other disorders of arteries and arterioles
0.903 0.097 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.099 0.901
D68 Other coagulation defects
0.898 0.102 0.000
D61.9 Aplastic anaemia, unspecified
0.896 0.104 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.106 0.894
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.106 0.894
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.109 0.891
E46 Unspecified protein-energy malnutrition
0.888 0.112 0.000
Q44.6 Cystic disease of liver
0.884 0.116 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.883 0.117 0.000
I77.1 Stricture of artery
0.882 0.118 0.000
E07.8 Other specified disorders of thyroid
0.879 0.121 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.879 0.121 0.000
I70 Atherosclerosis
0.877 0.123 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.874 0.126 0.000
H33.3 Retinal breaks without detachment
0.874 0.126 0.000
E21.0 Primary hyperparathyroidism
0.873 0.127 0.000
E14.8 With unspecified complications
0.868 0.132 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.867 0.133 0.000
M35.7 Hypermobility syndrome
0.867 0.133 0.000
D55-D59 Haemolytic anaemias
0.866 0.134 0.000
H34 Retinal vascular occlusions
0.863 0.137 0.000
I74 Arterial embolism and thrombosis
0.862 0.138 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.861 0.139 0.000
H35.4 Peripheral retinal degeneration
0.861 0.139 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.142 0.858
M07.3 Other psoriatic arthropathies
0.000 0.142 0.858
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.144 0.856
M32.1 Systemic lupus erythematosus with organ or system involvement
0.856 0.144 0.000
E10.8 With unspecified complications
0.856 0.144 0.000
D64.8 Other specified anaemias
0.851 0.149 0.000
I62 Other nontraumatic intracranial haemorrhage
0.849 0.151 0.000
E28.2 Polycystic ovarian syndrome
0.845 0.155 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.841 0.159 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.841 0.159 0.000
Q61.2 Polycystic kidney, adult type
0.839 0.161 0.000
E22 Hyperfunction of pituitary gland
0.838 0.162 0.000
E20 Hypoparathyroidism
0.838 0.162 0.000
M24 Other specific joint derangements
0.836 0.164 0.000
E10.5 With peripheral circulatory complications
0.834 0.166 0.000
E28.3 Primary ovarian failure
0.832 0.168 0.000
H35.8 Other specified retinal disorders
0.829 0.171 0.000
G20-G26 Extrapyramidal and movement disorders
0.828 0.172 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.172 0.828
D68.8 Other specified coagulation defects
0.826 0.174 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.825 0.175 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.825 0.175 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.825 0.175 0.000
Q61.0 Congenital single renal cyst
0.824 0.176 0.000
E10.0 With coma
0.824 0.176 0.000
E06 Thyroiditis
0.823 0.177 0.000
I63 Cerebral infarction
0.815 0.185 0.000
D69.4 Other primary thrombocytopenia
0.814 0.186 0.000
H35.2 Other proliferative retinopathy
0.814 0.186 0.000
D69.6 Thrombocytopenia, unspecified
0.813 0.187 0.000
N05.1 Focal and segmental glomerular lesions
0.812 0.188 0.000
N05.2 Diffuse membranous glomerulonephritis
0.810 0.190 0.000
G51 Facial nerve disorders
0.809 0.191 0.000
N20-N23 Urolithiasis
0.809 0.191 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.808 0.192 0.000
E34 Other endocrine disorders
0.805 0.195 0.000
Q61.9 Cystic kidney disease, unspecified
0.804 0.195 0.000
N17-N19 Renal failure
0.803 0.197 0.000
L10-L14 Bullous disorders
0.803 0.197 0.000
G58 Other mononeuropathies
0.802 0.198 0.000
E10.7 With multiple complications
0.800 0.200 0.000
Q39 Congenital malformations of oesophagus
0.799 0.201 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.799 0.201 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.202 0.798
Q00-Q07 Congenital malformations of the nervous system
0.797 0.203 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.797 0.203 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.796 0.204 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.796 0.204 0.000
D68.0 Von Willebrand's disease
0.795 0.205 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.206 0.794
M60 Myositis
0.793 0.207 0.000
N23 Unspecified renal colic
0.791 0.209 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.209 0.790
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.211 0.789
H33.0 Retinal detachment with retinal break
0.787 0.213 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.787 0.213 0.000
I15 Secondary hypertension
0.786 0.214 0.000
N18 Chronic renal failure
0.784 0.216 0.000
D68.6 Other Thrombophilia
0.782 0.218 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.781 0.219 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.777 0.223 0.000
M62 Other disorders of muscle
0.777 0.223 0.000
D80 Immunodeficiency with predominantly antibody defects
0.776 0.224 0.000
L13 Other bullous disorders
0.776 0.224 0.000
D86 Sarcoidosis
0.776 0.224 0.000
L40 Psoriasis
0.008 0.225 0.767
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.775 0.225 0.000
Q40 Other congenital malformations of upper alimentary tract
0.774 0.225 0.000
D50.1 Sideropenic dysphagia
0.774 0.226 0.000
E31 Polyglandular dysfunction
0.774 0.226 0.000
N04.1 Focal and segmental glomerular lesions
0.774 0.226 0.000
M24.1 Other articular cartilage disorders
0.773 0.227 0.000
E50-E64 Other nutritional deficiencies
0.771 0.229 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.771 0.229 0.000
H05.8 Other disorders of orbit
0.771 0.229 0.000
N18.3 Chronic kidney disease, stage 3
0.768 0.232 0.000
D61.0 Constitutional aplastic anaemia
0.766 0.233 0.000
E14.1 With ketoacidosis
0.766 0.234 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.235 0.765
H34.8 Other retinal vascular occlusions
0.765 0.235 0.000
E22.0 Acromegaly and pituitary gigantism
0.762 0.238 0.000
H00 Hordeolum and chalazion
0.252 0.240 0.508
C83.3 Large cell (diffuse)
0.760 0.240 0.000
G24 Dystonia
0.759 0.241 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.759 0.241 0.000
H35.0 Background retinopathy and retinal vascular changes
0.758 0.242 0.000
E14.2 Withrenal complications
0.758 0.242 0.000
E14.5 With peripheral circulatory complications
0.757 0.243 0.000
L13.0 Dermatitis herpetiformis
0.757 0.243 0.000
G30-G32 Other degenerative diseases of the nervous system
0.755 0.245 0.000
M15.1 Heberden's nodes (with arthropathy)
0.755 0.245 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.754 0.246 0.000
D52 Folate deficiency anaemia
0.753 0.247 0.000
Q44.4 Choledochal cyst
0.753 0.247 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.751 0.248 0.000
N04.2 Diffuse membranous glomerulonephritis
0.751 0.249 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.750 0.250 0.000
E21.2 Other hyperparathyroidism
0.749 0.251 0.000
Q63 Other congenital malformations of kidney
0.749 0.251 0.000
Q43.3 Congenital malformations of intestinal fixation
0.749 0.251 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.749 0.251 0.000
I70.0 Atherosclerosis of aorta
0.749 0.251 0.000
C81 Hodgkin's disease
0.747 0.253 0.000
I72 Other aneurysm
0.747 0.253 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.254 0.746
G58.9 Mononeuropathy, unspecified
0.746 0.254 0.000
N03 Chronic nephritic syndrome
0.746 0.254 0.000
Chapter XXII Codes for special purposes
0.744 0.256 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.742 0.258 0.000
M34 Systemic sclerosis
0.742 0.258 0.000
L20-L30 Dermatitis and eczema
0.739 0.261 0.000
D83 Common variable immunodeficiency
0.738 0.262 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.738 0.262 0.000
Q44.5 Other congenital malformations of bile ducts
0.736 0.264 0.000
G57 Mononeuropathies of lower limb
0.735 0.265 0.000
M15.4 Erosive (osteo)arthrosis
0.734 0.266 0.000
E27.9 Disorder of adrenal gland, unspecified
0.733 0.267 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.732 0.268 0.000
D59 Acquired haemolytic anaemia
0.732 0.268 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.731 0.269 0.000
Q44.7 Other congenital malformations of liver
0.729 0.271 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.726 0.274 0.000
Q61.5 Medullary cystic kidney
0.725 0.275 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.724 0.276 0.000
E20.9 Hypoparathyroidism, unspecified
0.723 0.277 0.000
Q43.1 Hirschsprung's disease
0.722 0.278 0.000
E24 Cushing's syndrome
0.722 0.278 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.721 0.279 0.000
E03.1 Congenital hypothyroidism without goitre
0.721 0.279 0.000
Q45 Other congenital malformations of digestive system
0.718 0.281 0.000
M24.5 Contracture of joint
0.718 0.282 0.000
G51.0 Bell's palsy
0.718 0.282 0.000
Q65 Congenital deformities of hip
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.716 0.283 0.000
D64.3 Other sideroblastic anaemias
0.716 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.716 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.716 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.716 0.283 0.000
E14.7 With multiple complications
0.716 0.284 0.000
E14.0 With coma
0.716 0.284 0.000
I20-I25 Ischaemic heart diseases
0.716 0.284 0.000
Q74 Other congenital malformations of limb(s)
0.716 0.284 0.000
H05.0 Acute inflammation of orbit
0.715 0.285 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.714 0.286 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.714 0.286 0.000
Q43.0 Meckel's diverticulum
0.714 0.286 0.000
L50-L54 Urticaria and erythema
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
Q43.8 Other specified congenital malformations of intestine
0.713 0.287 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.713 0.287 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.712 0.287 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.712 0.287 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.712 0.287 0.000
M60.9 Myositis, unspecified
0.712 0.288 0.000
Q35-Q37 Cleft lip and cleft palate
0.711 0.288 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.711 0.289 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.711 0.289 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.711 0.289 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.711 0.289 0.000
H04 Disorders of lachrymal system
0.710 0.290 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.710 0.290 0.000
C85.1 B-cell lymphoma, unspecified
0.710 0.290 0.000
E29 Testicular dysfunction
0.710 0.290 0.000
E15 Nondiabetic hypoglycaemic coma
0.709 0.290 0.000
Q61.8 Other cystic kidney diseases
0.709 0.291 0.000
Q61.4 Renal dysplasia
0.709 0.291 0.000
Q61.1 Polycystic kidney, infantile type
0.709 0.291 0.000
I73 Other peripheral vascular diseases
0.709 0.291 0.000
N40 Hyperplasia of prostate
0.000 0.291 0.709
E34.8 Other specified endocrine disorders
0.708 0.292 0.000
I79.1 Aortitis in diseases classified elsewhere
0.708 0.292 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.708 0.292 0.000
M33 Dermatopolymyositis
0.707 0.293 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.707 0.293 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.293 0.707
M06.38 Rheumatoid nodule (Other)
0.000 0.293 0.707
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.293 0.707
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.293 0.707
M06.33 Rheumatoid nodule (Forearm)
0.000 0.293 0.707
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.293 0.707
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.293 0.707
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.293 0.707
I00-I02 Acute rheumatic fever
0.707 0.293 0.000
C83.7 Burkitt's tumour
0.706 0.293 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.706 0.294 0.000
G56.4 Causalgia
0.706 0.294 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.705 0.295 0.000
Chapter VIII Diseases of the ear and mastoid process
0.705 0.295 0.000
E21.4 Other specified disorders of parathyroid gland
0.705 0.295 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.704 0.296 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.704 0.296 0.000
E16.4 Abnormal secretion of gastrin
0.704 0.296 0.000
E16.3 Increased secretion of glucagon
0.704 0.296 0.000
H33.1 Retinoschisis and retinal cysts
0.704 0.296 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.704 0.296 0.000
H33.4 Traction detachment of retina
0.702 0.298 0.000
I13 Hypertensive heart and renal disease
0.702 0.298 0.000
M35.1 Other overlap syndromes
0.702 0.298 0.000
M62.8 Other specified disorders of muscle
0.702 0.298 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.701 0.299 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.701 0.299 0.000
M35.5 Multifocal fibrosclerosis
0.701 0.299 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.701 0.299 0.000
Q60.6 Potter's syndrome
0.701 0.299 0.000
Q60.5 Renal hypoplasia, unspecified
0.701 0.299 0.000
Q60.4 Renal hypoplasia, bilateral
0.701 0.299 0.000
Q60.3 Renal hypoplasia, unilateral
0.701 0.299 0.000
Q60.1 Renal agenesis, bilateral
0.701 0.299 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.699 0.301 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.699 0.301 0.000
D51.2 Transcobalamin II deficiency
0.699 0.301 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.699 0.301 0.000
N05.8 Other
0.699 0.301 0.000
M23 Internal derangement of knee
0.698 0.302 0.000
D67 Hereditary factor IX deficiency
0.697 0.303 0.000
M12 Other specific arthropathies
0.000 0.303 0.697
H36.8 Other retinal disorders in diseases classified elsewhere
0.697 0.303 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.695 0.305 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.695 0.305 0.000
H34.2 Other retinal artery occlusions
0.694 0.306 0.000
G11 Hereditary ataxia
0.693 0.307 0.000
D69.2 Other nonthrombocytopenic purpura
0.692 0.308 0.000
I70.1 Atherosclerosis of renal artery
0.692 0.308 0.000
D89.1 Cryoglobulinaemia
0.691 0.309 0.000
I77.2 Rupture of artery
0.691 0.309 0.000
D61.1 Drug-induced aplastic anaemia
0.690 0.310 0.000
D53 Other nutritional anaemias
0.690 0.310 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.689 0.310 0.000
M15.8 Other polyarthrosis
0.689 0.311 0.000
N00 Acute nephritic syndrome
0.689 0.311 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.689 0.311 0.000
D68.1 Hereditary factor XI deficiency
0.689 0.311 0.000
D69.5 Secondary thrombocytopenia
0.688 0.312 0.000
H35.6 Retinal haemorrhage
0.688 0.312 0.000
I24 Other acute ischaemic heart diseases
0.687 0.313 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.687 0.313 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.686 0.314 0.000
E27.5 Adrenomedullary hyperfunction
0.686 0.314 0.000
E27.0 Other adrenocortical overactivity
0.686 0.314 0.000
I70.8 Atherosclerosis of other arteries
0.685 0.315 0.000
H30 Chorioretinal inflammation
0.685 0.315 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.685 0.315 0.000
N06 Isolated proteinuria with specified morphological lesion
0.685 0.315 0.000
N01 Rapidly progressive nephritic syndrome
0.685 0.315 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.684 0.316 0.000
C81.1 Nodular sclerosis
0.684 0.316 0.000
E03.8 Other specified hypothyroidism
0.684 0.316 0.000
C88 Malignant immunoproliferative diseases
0.683 0.316 0.000
H60-H62 Diseases of external ear
0.683 0.317 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.683 0.317 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.683 0.317 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.683 0.317 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.683 0.317 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.683 0.317 0.000
E14.6 With other specified complications
0.683 0.317 0.000
C92 Myeloid leukaemia
0.683 0.317 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.317 0.682
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.317 0.682
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.317 0.682
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.317 0.682
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.317 0.682
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.317 0.682
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.317 0.682
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.317 0.682
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.682 0.318 0.000
H05.3 Deformity of orbit
0.682 0.318 0.000
H05.1 Chronic inflammatory disorders of orbit
0.682 0.318 0.000
D81 Combined immunodeficiencies
0.682 0.318 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.682 0.318 0.000
Q44.2 Atresia of bile ducts
0.682 0.318 0.000
Q44.1 Other congenital malformations of gallbladder
0.682 0.318 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.682 0.318 0.000
E70-E90 Metabolic disorders
0.681 0.319 0.000
G24.9 Dystonia, unspecified
0.681 0.319 0.000
D61.8 Other specified aplastic anaemias
0.681 0.319 0.000
D61.3 Idiopathic aplastic anaemia
0.681 0.319 0.000
D61.2 Aplastic anaemia due to other external agents
0.681 0.319 0.000
G12 Spinal muscular atrophy and related syndromes
0.681 0.319 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.681 0.319 0.000
D58 Other hereditary haemolytic anaemias
0.681 0.319 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.680 0.320 0.000
I22 Subsequent myocardial infarction
0.680 0.320 0.000
Q43.7 Persistent cloaca
0.679 0.321 0.000
Q43.6 Congenital fistula of rectum and anus
0.679 0.321 0.000
Q43.5 Ectopic anus
0.679 0.321 0.000
Q43.4 Duplication of intestine
0.679 0.321 0.000
Q43.2 Other congenital functional disorders of colon
0.679 0.321 0.000
E06.3 Autoimmune thyroiditis
0.679 0.321 0.000
I74.5 Embolism and thrombosis of iliac artery
0.678 0.322 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.678 0.322 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.678 0.322 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.678 0.322 0.000
G59.0 Diabetic mononeuropathy
0.677 0.323 0.000
E14.4 With neurological complications
0.677 0.323 0.000
Q38.1 Ankyloglossia
0.677 0.323 0.000
E28.9 Ovarian dysfunction, unspecified
0.676 0.324 0.000
E28.8 Other ovarian dysfunction
0.676 0.324 0.000
E28.1 Androgen excess
0.676 0.324 0.000
E28.0 Oestrogen excess
0.676 0.324 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.676 0.324 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.676 0.324 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.675 0.324 0.000
D69.9 Haemorrhagic condition, unspecified
0.675 0.325 0.000
N04.8 Other
0.674 0.325 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.674 0.325 0.000
N04.6 Dense deposit disease
0.674 0.325 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.674 0.325 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.674 0.325 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.674 0.325 0.000
N04.0 Minor glomerular abnormality
0.674 0.325 0.000
I24.8 Other forms of acute ischaemic heart disease
0.674 0.326 0.000
H61 Other disorders of external ear
0.674 0.326 0.000
E23 Hypofunction and other disorders of pituitary gland
0.672 0.328 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.328 0.672
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.328 0.672
G14 Postpolio syndrome
0.672 0.328 0.000
H04.8 Other disorders of lachrymal system
0.671 0.329 0.000
Q39.9 Congenital malformation of oesophagus, unspecified
0.671 0.329 0.000
M15.0 Primary generalised (osteo)arthrosis
0.671 0.329 0.000
M15.3 Secondary multiple arthrosis
0.671 0.329 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.671 0.329 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.670 0.330 0.000
E45 Retarded development following protein-energy malnutrition
0.670 0.330 0.000
E43 Unspecified severe protein-energy malnutrition
0.670 0.330 0.000
E42 Marasmic kwashiorkor
0.670 0.330 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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