TreeWAS – Variant ID: rs3129945

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E10.1 With ketoacidosis	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
M15-M19 Arthrosis	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
H00.1 Chalazion	0.000	0.000	1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
M18 Arthrosis of first carpometacarpal joint	1.000	0.000	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.999	0.001	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.002	0.998
R31 Unspecified haematuria	0.000	0.002	0.998
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.003	0.997
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.003	0.997
M05-M14 Inflammatory polyarthropathies	0.007	0.003	0.990
M05 Seropositive rheumatoid arthritis	0.003	0.004	0.993
M17.1 Other primary gonarthrosis	0.994	0.006	0.000
M17 Gonarthrosis [arthrosis of knee]	0.993	0.007	0.000
E03 Other hypothyroidism	0.993	0.007	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.993	0.007	0.000
H43-H45 Disorders of vitreous body and globe	0.992	0.008	0.000
H43 Disorders of vitreous body	0.990	0.010	0.000
D60-D64 Aplastic and other anaemias	0.988	0.012	0.000
E03.9 Hypothyroidism, unspecified	0.988	0.012	0.000
E14.3 With ophthalmic complications	0.988	0.012	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.013	0.987
E14.9 Without complications	0.987	0.013	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.984	0.016	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.983	0.017	0.000
D80-D89 Certain disorders involving the immune mechanism	0.983	0.017	0.000
E10.2 With renal complications	0.982	0.018	0.000
E10.4 With neurological complications	0.979	0.021	0.000
H43.8 Other disorders of vitreous body	0.978	0.022	0.000
M23 Internal derangement of knee	0.977	0.023	0.000
E20-E35 Disorders of other endocrine glands	0.976	0.024	0.000
D64 Other anaemias	0.975	0.025	0.000
Q60-Q64 Congenital malformations of the urinary system	0.974	0.026	0.000
D50-D53 Nutritional anaemias	0.973	0.027	0.000
M24 Other specific joint derangements	0.967	0.033	0.000
M23.3 Other meniscus derangements	0.962	0.038	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.960	0.040	0.000
Chapter IX Diseases of the circulatory system	0.957	0.043	0.000
H43.1 Vitreous haemorrhage	0.956	0.044	0.000
M06.3 Rheumatoid nodule	0.000	0.044	0.956
D64.9 Anaemia, unspecified	0.951	0.049	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.049	0.951
M24.1 Other articular cartilage disorders	0.948	0.052	0.000
D50 Iron deficiency anaemia	0.947	0.053	0.000
Chapter VI Diseases of the nervous system	0.945	0.055	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.943	0.057	0.000
I73 Other peripheral vascular diseases	0.942	0.058	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.942	0.058	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.939	0.061	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.933	0.067	0.000
D50.9 Iron deficiency anaemia, unspecified	0.932	0.068	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.069	0.931
G56 Mononeuropathies of upper limb	0.931	0.069	0.000
G56.0 Carpal tunnel syndrome	0.927	0.073	0.000
M60-M63 Disorders of muscles	0.925	0.075	0.000
Q43 Other congenital malformations of intestine	0.922	0.078	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.922	0.078	0.000
D86 Sarcoidosis	0.921	0.079	0.000
E22 Hyperfunction of pituitary gland	0.917	0.083	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.916	0.084	0.000
D61 Other aplastic anaemias	0.916	0.084	0.000
E89.0 Postprocedural hypothyroidism	0.914	0.086	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.913	0.087	0.000
H34 Retinal vascular occlusions	0.912	0.088	0.000
I73.0 Raynaud's syndrome	0.911	0.089	0.000
E06 Thyroiditis	0.909	0.091	0.000
E70-E90 Metabolic disorders	0.906	0.094	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.906	0.094	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.900	0.100	0.000
M15 Polyarthrosis	0.900	0.100	0.000
M32 Systemic lupus erythematosus	0.899	0.101	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.898	0.102	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.102	0.898
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.897	0.103	0.000
G51 Facial nerve disorders	0.896	0.104	0.000
E27 Other disorders of adrenal gland	0.895	0.105	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.894	0.106	0.000
I74 Arterial embolism and thrombosis	0.893	0.107	0.000
M34 Systemic sclerosis	0.889	0.111	0.000
E10.8 With unspecified complications	0.889	0.111	0.000
E50-E64 Other nutritional deficiencies	0.889	0.111	0.000
E27.1 Primary adrenocortical insufficiency	0.888	0.112	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.122	0.878
Q61 Cystic kidney disease	0.874	0.126	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.130	0.870
D64.8 Other specified anaemias	0.868	0.132	0.000
Q39 Congenital malformations of oesophagus	0.867	0.133	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.866	0.134	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.866	0.134	0.000
E40-E46 Malnutrition	0.864	0.136	0.000
E14.8 With unspecified complications	0.861	0.139	0.000
I73.9 Peripheral vascular disease, unspecified	0.861	0.139	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.861	0.139	0.000
Q60.2 Renal agenesis, unspecified	0.860	0.140	0.000
E10.5 With peripheral circulatory complications	0.859	0.141	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.852	0.145	0.003
G20-G26 Extrapyramidal and movement disorders	0.855	0.145	0.000
E14.1 With ketoacidosis	0.850	0.150	0.000
M35.1 Other overlap syndromes	0.848	0.152	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.846	0.154	0.000
E53 Deficiency of other B group vitamins	0.845	0.155	0.000
D80 Immunodeficiency with predominantly antibody defects	0.845	0.155	0.000
M23.4 Loose body in knee	0.842	0.158	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.842	0.158	0.000
G51.0 Bell's palsy	0.841	0.159	0.000
E06.3 Autoimmune thyroiditis	0.840	0.160	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.840	0.160	0.000
E10.0 With coma	0.837	0.162	0.000
D61.9 Aplastic anaemia, unspecified	0.837	0.163	0.000
M60 Myositis	0.837	0.163	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.834	0.166	0.000
M00-M03 Infectious arthropathies	0.832	0.168	0.000
H34.8 Other retinal vascular occlusions	0.829	0.171	0.000
D86.3 Sarcoidosis of skin	0.827	0.173	0.000
Q60.0 Renal agenesis, unilateral	0.827	0.173	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.826	0.174	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.824	0.175	0.002
E28 Ovarian dysfunction	0.824	0.176	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.823	0.177	0.000
D86.9 Sarcoidosis, unspecified	0.823	0.177	0.000
M35.7 Hypermobility syndrome	0.822	0.178	0.000
E53.8 Deficiency of other specified B group vitamins	0.822	0.178	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.821	0.179	0.000
M23.5 Chronic instability of knee	0.821	0.179	0.000
I77 Other disorders of arteries and arterioles	0.819	0.181	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.189	0.811
E07 Other disorders of thyroid	0.809	0.191	0.000
Q00-Q07 Congenital malformations of the nervous system	0.807	0.192	0.000
Q44.6 Cystic disease of liver	0.807	0.193	0.000
H06.2 Dysthyroid exophthalmos	0.804	0.196	0.000
E22.0 Acromegaly and pituitary gigantism	0.803	0.197	0.000
M24.5 Contracture of joint	0.803	0.197	0.000
D83 Common variable immunodeficiency	0.797	0.203	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.796	0.203	0.000
E88 Other metabolic disorders	0.796	0.204	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.796	0.204	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.205	0.795
E10.7 With multiple complications	0.794	0.206	0.000
D51 Vitamin B12 deficiency anaemia	0.789	0.211	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.786	0.214	0.000
E22.1 Hyperprolactinaemia	0.784	0.216	0.000
H05 Disorders of orbit	0.783	0.216	0.001
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.782	0.218	0.000
M24.0 Loose body in joint	0.781	0.219	0.000
H30 Chorioretinal inflammation	0.781	0.219	0.000
I77.1 Stricture of artery	0.780	0.220	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.780	0.220	0.000
D68 Other coagulation defects	0.778	0.222	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.222	0.778
E73 Lactose intolerance	0.777	0.223	0.000
D55-D59 Haemolytic anaemias	0.774	0.226	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.227	0.773
G20 Parkinson's disease	0.771	0.229	0.000
E31 Polyglandular dysfunction	0.770	0.230	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.233	0.767
E14.5 With peripheral circulatory complications	0.767	0.233	0.000
E46 Unspecified protein-energy malnutrition	0.766	0.234	0.000
M33 Dermatopolymyositis	0.765	0.235	0.000
M14 Arthropathies in other diseases classified elsewhere	0.004	0.235	0.761
I70 Atherosclerosis	0.763	0.237	0.000
M62 Other disorders of muscle	0.763	0.237	0.000
E14.2 Withrenal complications	0.763	0.237	0.000
D50.8 Other iron deficiency anaemias	0.762	0.238	0.000
M60.9 Myositis, unspecified	0.762	0.238	0.000
G12 Spinal muscular atrophy and related syndromes	0.762	0.238	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.761	0.239	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.760	0.240	0.000
Q65 Congenital deformities of hip	0.759	0.241	0.000
H43.2 Crystalline deposits in vitreous body	0.758	0.242	0.000
E24 Cushing's syndrome	0.758	0.242	0.000
M23.8 Other internal derangements of knee	0.757	0.243	0.000
E16.1 Other hypoglycaemia	0.756	0.244	0.000
D69 Purpura and other haemorrhagic conditions	0.755	0.245	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.752	0.248	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.752	0.248	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.749	0.251	0.000
H00 Hordeolum and chalazion	0.215	0.252	0.533
Q43.3 Congenital malformations of intestinal fixation	0.747	0.253	0.000
D61.0 Constitutional aplastic anaemia	0.745	0.255	0.000
D86.8 Sarcoidosis of other and combined sites	0.743	0.257	0.000
Q61.3 Polycystic kidney, unspecified	0.743	0.257	0.000
M34.0 Progressive systemic sclerosis	0.740	0.260	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.740	0.260	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.739	0.261	0.000
Q74 Other congenital malformations of limb(s)	0.736	0.264	0.000
Q45 Other congenital malformations of digestive system	0.734	0.266	0.000
E34 Other endocrine disorders	0.734	0.266	0.000
M15.8 Other polyarthrosis	0.730	0.270	0.000
H50 Other strabismus	0.729	0.271	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.271	0.729
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.728	0.272	0.000
M86-M90 Other osteopathies	0.728	0.272	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.728	0.272	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.727	0.273	0.000
M23.0 Cystic meniscus	0.726	0.274	0.000
G24 Dystonia	0.726	0.274	0.000
G58 Other mononeuropathies	0.726	0.274	0.000
G52 Disorders of other cranial nerves	0.725	0.275	0.000
Q35-Q37 Cleft lip and cleft palate	0.724	0.276	0.000
I71 Aortic aneurysm and dissection	0.724	0.276	0.000
Q38.7 Pharyngeal pouch	0.723	0.277	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.723	0.277	0.000
H05.2 Exophthalmic conditions	0.722	0.278	0.000
Q39.6 Diverticulum of oesophagus	0.722	0.278	0.000
M17.5 Other secondary gonarthrosis	0.721	0.279	0.000
N00-N08 Glomerular diseases	0.721	0.279	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.280	0.720
N04 Nephrotic syndrome	0.720	0.280	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.719	0.281	0.000
I05-I09 Chronic rheumatic heart diseases	0.719	0.281	0.000
H34.2 Other retinal artery occlusions	0.718	0.282	0.000
M23.49 Loose body in knee-Unspec lig/men	0.718	0.282	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M06.1 Adult-onset Still's disease	0.000	0.283	0.717
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.717	0.283	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.717	0.283	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.717	0.283	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.285	0.715
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.285	0.715
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.285	0.715
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.285	0.715
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.285	0.715
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.285	0.715
M09 Juvenile arthritis in diseases classified elsewhere	0.005	0.285	0.710
M08 Juvenile arthritis	0.005	0.285	0.710
H46-H48 Disorders of optic nerve and visual pathways	0.715	0.285	0.000
G30-G32 Other degenerative diseases of the nervous system	0.715	0.285	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.715	0.285	0.000
E07.8 Other specified disorders of thyroid	0.715	0.285	0.000
N04.9 Unspecified	0.715	0.285	0.000
M05.8 Other seropositive rheumatoid arthritis	0.002	0.286	0.712
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.286	0.712
M05.2 Rheumatoid vasculitis	0.002	0.286	0.712
M05.1 Rheumatoid lung disease	0.002	0.286	0.712
M05.0 Felty's syndrome	0.002	0.286	0.712
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.286	0.714
N08 Glomerular disorders in diseases classified elsewhere	0.713	0.287	0.000
M00 Pyogenic arthritis	0.713	0.287	0.000
H33 Retinal detachments and breaks	0.713	0.287	0.000
G11 Hereditary ataxia	0.712	0.288	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.712	0.288	0.000
E03.5 Myxoedema coma	0.712	0.288	0.000
E03.4 Atrophy of thyroid (acquired)	0.712	0.288	0.000
E03.3 Postinfectious hypothyroidism	0.712	0.288	0.000
E03.1 Congenital hypothyroidism without goitre	0.712	0.288	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.712	0.288	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.712	0.288	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.712	0.288	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.711	0.288	0.000
G51.9 Disorder of facial nerve, unspecified	0.712	0.288	0.000
Q38.1 Ankyloglossia	0.710	0.289	0.000
H43.0 Vitreous prolapse	0.710	0.290	0.000
Q61.0 Congenital single renal cyst	0.710	0.290	0.000
Q68 Other congenital musculoskeletal deformities	0.709	0.291	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.709	0.291	0.000
Q61.9 Cystic kidney disease, unspecified	0.708	0.292	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.707	0.293	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.707	0.293	0.000
Q63 Other congenital malformations of kidney	0.707	0.293	0.000
G54 Nerve root and plexus disorders	0.706	0.294	0.000
E88.8 Other specified metabolic disorders	0.705	0.295	0.000
G56.8 Other mononeuropathies of upper limb	0.705	0.295	0.000
D82 Immunodeficiency associated with other major defects	0.705	0.295	0.000
D81 Combined immunodeficiencies	0.705	0.295	0.000
E13 Other specified diabetes mellitus	0.704	0.295	0.000
M07 Psoriatic and enteropathic arthropathies	0.003	0.296	0.700
E06.5 Other chronic thyroiditis	0.702	0.298	0.000
Q43.1 Hirschsprung's disease	0.700	0.299	0.000
Q78 Other osteochondrodysplasias	0.700	0.300	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.700	0.300	0.000
E32 Diseases of thymus	0.700	0.300	0.000
E30 Disorders of puberty, not elsewhere classified	0.700	0.300	0.000
E25 Adrenogenital disorders	0.700	0.300	0.000
D64.4 Congenital dyserythropoietic anaemia	0.699	0.301	0.000
D64.3 Other sideroblastic anaemias	0.699	0.301	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.699	0.301	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.699	0.301	0.000
D64.0 Hereditary sideroblastic anaemia	0.699	0.301	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.699	0.301	0.000
M34.8 Other forms of systemic sclerosis	0.699	0.301	0.000
I00-I02 Acute rheumatic fever	0.699	0.301	0.000
G70-G73 Diseases of myoneural junction and muscle	0.699	0.301	0.000
Q40 Other congenital malformations of upper alimentary tract	0.698	0.302	0.000
H43.9 Disorder of vitreous body, unspecified	0.698	0.302	0.000
N05 Unspecified nephritic syndrome	0.697	0.303	0.000
M24.6 Ankylosis of joint	0.697	0.303	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.696	0.304	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.696	0.304	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.696	0.304	0.000
D68.8 Other specified coagulation defects	0.695	0.305	0.000
M60.99 Myositis, unspecified (Site unspecified)	0.695	0.305	0.000
E14.6 With other specified complications	0.694	0.306	0.000
M24.7 Protrusio acetabuli	0.693	0.306	0.000
M24.9 Joint derangement, unspecified	0.693	0.307	0.000
D53 Other nutritional anaemias	0.692	0.308	0.000
E89.2 Postprocedural hypoparathyroidism	0.691	0.309	0.000
G59.0 Diabetic mononeuropathy	0.691	0.309	0.000
G12.2 Motor neuron disease	0.691	0.309	0.000
Q44.5 Other congenital malformations of bile ducts	0.691	0.309	0.000
H49 Paralytic strabismus	0.690	0.310	0.000
M23.37 Other meniscus derangements-Capsular lig	0.690	0.310	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.689	0.311	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.689	0.311	0.000
Q64 Other congenital malformations of urinary system	0.689	0.311	0.000
Q76 Congenital malformations of spine and bony thorax	0.687	0.312	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.687	0.313	0.000
M34.1 CR(E)ST syndrome	0.687	0.313	0.000
M15.4 Erosive (osteo)arthrosis	0.686	0.314	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.314	0.685
M06.38 Rheumatoid nodule (Other)	0.000	0.314	0.685
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.314	0.685
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.314	0.685
M06.33 Rheumatoid nodule (Forearm)	0.000	0.314	0.685
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.314	0.685
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.314	0.685
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.314	0.685
E51 Thiamine deficiency	0.685	0.315	0.000
G56.1 Other lesions of median nerve	0.685	0.315	0.000
E73.9 Lactose intolerance, unspecified	0.684	0.316	0.000
G56.4 Causalgia	0.683	0.316	0.000
M23.1 Discoid meniscus (congenital)	0.683	0.317	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.683	0.317	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.681	0.319	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.680	0.320	0.000
M24.18 Other articular cartilage disorders (Other)	0.680	0.320	0.000
M24.14 Other articular cartilage disorders (Hand)	0.680	0.320	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.680	0.320	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.680	0.320	0.000
D50.1 Sideropenic dysphagia	0.679	0.321	0.000
Q66 Congenital deformities of feet	0.678	0.322	0.000
G51.3 Clonic hemifacial spasm	0.677	0.323	0.000
E14.4 With neurological complications	0.675	0.325	0.000
I20-I25 Ischaemic heart diseases	0.674	0.326	0.000
Q50-Q56 Congenital malformations of genital organs	0.674	0.326	0.000
G58.9 Mononeuropathy, unspecified	0.674	0.326	0.000
I79.1 Aortitis in diseases classified elsewhere	0.673	0.327	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.673	0.327	0.000
E28.3 Primary ovarian failure	0.670	0.330	0.000
H34.1 Central retinal artery occlusion	0.670	0.330	0.000
Q60.6 Potter's syndrome	0.669	0.331	0.000
Q60.5 Renal hypoplasia, unspecified	0.669	0.331	0.000
Q60.4 Renal hypoplasia, bilateral	0.669	0.331	0.000
Q60.3 Renal hypoplasia, unilateral	0.669	0.331	0.000
Q60.1 Renal agenesis, bilateral	0.669	0.331	0.000
M34.9 Systemic sclerosis, unspecified	0.669	0.331	0.000
H35 Other retinal disorders	0.668	0.332	0.000
E10.6 With other specified complications	0.668	0.332	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.334	0.666
Q43.8 Other specified congenital malformations of intestine	0.665	0.335	0.000
D83.9 Common variable immunodeficiency, unspecified	0.663	0.337	0.000
Q03 Congenital hydrocephalus	0.663	0.337	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.663	0.337	0.000
M61 Calcification and ossification of muscle	0.663	0.337	0.000
D68.0 Von Willebrand's disease	0.662	0.338	0.000
Q43.7 Persistent cloaca	0.661	0.339	0.000
Q43.6 Congenital fistula of rectum and anus	0.661	0.339	0.000
Q43.5 Ectopic anus	0.661	0.339	0.000
Q43.4 Duplication of intestine	0.661	0.339	0.000
Q43.2 Other congenital functional disorders of colon	0.661	0.339	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.661	0.339	0.000
Q75 Other congenital malformations of skull and face bones	0.661	0.339	0.000
Q73 Reduction defects of unspecified limb	0.661	0.339	0.000
Q72 Reduction defects of lower limb	0.661	0.339	0.000
Q71 Reduction defects of upper limb	0.661	0.339	0.000
Q70 Syndactyly	0.661	0.339	0.000
Q69 Polydactyly	0.661	0.339	0.000
D52 Folate deficiency anaemia	0.661	0.339	0.000
E03.8 Other specified hypothyroidism	0.660	0.339	0.000
I24 Other acute ischaemic heart diseases	0.661	0.339	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.660	0.340	0.000
E28.2 Polycystic ovarian syndrome	0.659	0.341	0.000
M15.1 Heberden's nodes (with arthropathy)	0.658	0.342	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.658	0.342	0.000
M24.51 Contracture of joint (Shoulder region)	0.657	0.343	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.657	0.343	0.000
E22.8 Other hyperfunction of pituitary gland	0.657	0.343	0.000
G51.8 Other disorders of facial nerve	0.657	0.343	0.000
D61.8 Other specified aplastic anaemias	0.657	0.343	0.000
D61.3 Idiopathic aplastic anaemia	0.657	0.343	0.000
D61.2 Aplastic anaemia due to other external agents	0.657	0.343	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.344	0.656
E20 Hypoparathyroidism	0.656	0.344	0.000
M86 Osteomyelitis	0.655	0.345	0.000
E29 Testicular dysfunction	0.655	0.345	0.000
D61.1 Drug-induced aplastic anaemia	0.654	0.346	0.000
H34.0 Transient retinal artery occlusion	0.654	0.346	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.654	0.346	0.000
M35.8 Other specified systemic involvement of connective tissue	0.652	0.347	0.000
M24.01 Loose body in joint (Shoulder region)	0.652	0.348	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.652	0.348	0.000
I24.8 Other forms of acute ischaemic heart disease	0.652	0.348	0.000
E06.4 Drug-induced thyroiditis	0.651	0.348	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.651	0.348	0.000
E06.1 Subacute thyroiditis	0.651	0.348	0.000
E06.0 Acute thyroiditis	0.651	0.348	0.000
D68.6 Other Thrombophilia	0.651	0.349	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.650	0.349	0.000
E77 Disorders of glycoprotein metabolism	0.650	0.350	0.000
E76 Disorders of glycosaminoglycan metabolism	0.650	0.350	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.650	0.350	0.000
E72 Other disorders of amino-acid metabolism	0.650	0.350	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.650	0.350	0.000
E70 Disorders of aromatic amino-acid metabolism	0.650	0.350	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.650	0.350	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.650	0.350	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.650	0.350	0.000
E89.5 Postprocedural testicular hypofunction	0.650	0.350	0.000
E89.4 Postprocedural ovarian failure	0.650	0.350	0.000
E89.1 Postprocedural hypoinsulinaemia	0.650	0.350	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.649	0.351	0.000
E11 Non-insulin-dependent diabetes mellitus	0.649	0.351	0.000
D84 Other immunodeficiencies	0.647	0.353	0.000
M14.6 Neuropathic arthropathy	0.002	0.353	0.645
I74.8 Embolism and thrombosis of other arteries	0.647	0.353	0.000
M15.0 Primary generalised (osteo)arthrosis	0.645	0.355	0.000
M15.3 Secondary multiple arthrosis	0.645	0.355	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.644	0.356	0.000
M32.8 Other forms of systemic lupus erythematosus	0.644	0.356	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.644	0.356	0.000
D67 Hereditary factor IX deficiency	0.643	0.357	0.000
Q65.8 Other congenital deformities of hip	0.643	0.357	0.000
G51.4 Facial myokymia	0.642	0.358	0.000
G51.2 Melkersson's syndrome	0.642	0.358	0.000
G51.1 Geniculate ganglionitis	0.642	0.358	0.000
N05.2 Diffuse membranous glomerulonephritis	0.642	0.358	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.642	0.358	0.000
E27.5 Adrenomedullary hyperfunction	0.642	0.358	0.000
E27.0 Other adrenocortical overactivity	0.642	0.358	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.642	0.358	0.000
Q44.7 Other congenital malformations of liver	0.641	0.359	0.000
Q44.4 Choledochal cyst	0.641	0.359	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.641	0.359	0.000
Q44.2 Atresia of bile ducts	0.641	0.359	0.000
Q44.1 Other congenital malformations of gallbladder	0.641	0.359	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.641	0.359	0.000
M35.2 Behcet's disease	0.641	0.359	0.000
M24.54 Contracture of joint (Hand)	0.641	0.359	0.000
M60.0 Infective myositis	0.640	0.360	0.000
H34.9 Retinal vascular occlusion, unspecified	0.639	0.360	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.637	0.362	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.637	0.363	0.000
E63 Other nutritional deficiencies	0.637	0.363	0.000
E56 Other vitamin deficiencies	0.637	0.363	0.000
E50 Vitamin A deficiency	0.637	0.363	0.000
E60 Dietary zinc deficiency	0.637	0.363	0.000
E59 Dietary selenium deficiency	0.637	0.363	0.000
E58 Dietary calcium deficiency	0.637	0.363	0.000
E54 Ascorbic acid deficiency	0.637	0.363	0.000
E52 Niacin deficiency [pellagra]	0.637	0.363	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.636	0.363	0.000
D69.6 Thrombocytopenia, unspecified	0.636	0.364	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations