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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129988
log Bayes Factor = 30.4662
Chromosome 6   position 30,769,478  (GRCh37) Explore rs3129988 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.028 0.972
E11.9 Without complications
0.000 0.029 0.971
L40 Psoriasis
0.000 0.036 0.964
E14 Unspecified diabetes mellitus
0.000 0.039 0.961
G35-G37 Demyelinating diseases of the central nervous system
0.951 0.049 0.000
L40.5 Arthropathic psoriasis
0.000 0.055 0.945
E11.5 With peripheral circulatory complications
0.000 0.079 0.921
E14.9 Without complications
0.000 0.088 0.912
E11.4 With neurological complications
0.000 0.089 0.911
Chapter VI Diseases of the nervous system
0.879 0.121 0.000
E10.4 With neurological complications
0.000 0.158 0.842
G90-G99 Other disorders of the nervous system
0.841 0.159 0.000
E10.2 With renal complications
0.000 0.162 0.838
G00-G09 Inflammatory diseases of the central nervous system
0.826 0.174 0.000
G30-G32 Other degenerative diseases of the nervous system
0.820 0.180 0.000
G37 Other demyelinating diseases of central nervous system
0.818 0.182 0.000
E10.1 With ketoacidosis
0.000 0.183 0.816
E14.3 With ophthalmic complications
0.000 0.188 0.812
E13 Other specified diabetes mellitus
0.000 0.199 0.801
G20-G26 Extrapyramidal and movement disorders
0.801 0.199 0.000
L40.0 Psoriasis vulgaris
0.000 0.218 0.782
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.775 0.225 0.000
E11.0 With coma
0.000 0.233 0.767
E11.2 With renal complications
0.000 0.233 0.767
G31.9 Degenerative disease of nervous system, unspecified
0.741 0.259 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.738 0.262 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.263 0.737
G37.9 Demyelinating disease of central nervous system, unspecified
0.736 0.264 0.000
E11.1 With ketoacidosis
0.000 0.277 0.723
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E11.7 With multiple complications
0.000 0.287 0.713
E11.6 With other specified complications
0.000 0.287 0.713
G03 Meningitis due to other and unspecified causes
0.707 0.293 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.695 0.305 0.000
L40.8 Other psoriasis
0.000 0.309 0.691
L40.4 Guttate psoriasis
0.000 0.309 0.691
L40.3 Pustulosis palmaris et plantaris
0.000 0.309 0.691
L40.2 Acrodermatitis continua
0.000 0.309 0.691
L40.1 Generalised pustular psoriasis
0.000 0.309 0.691
E14.8 With unspecified complications
0.000 0.311 0.689
E14.7 With multiple complications
0.000 0.311 0.689
E14.6 With other specified complications
0.000 0.311 0.689
E14.5 With peripheral circulatory complications
0.000 0.311 0.689
E14.4 With neurological complications
0.000 0.311 0.689
E14.2 Withrenal complications
0.000 0.311 0.689
E14.1 With ketoacidosis
0.000 0.311 0.689
E14.0 With coma
0.000 0.311 0.689
G36 Other acute disseminated demyelination
0.682 0.318 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.677 0.323 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.674 0.326 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.674 0.326 0.000
E10.5 With peripheral circulatory complications
0.000 0.327 0.673
G96 Other disorders of central nervous system
0.671 0.329 0.000
G20 Parkinson's disease
0.671 0.329 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.670 0.330 0.000
G93 Other disorders of brain
0.670 0.330 0.000
E10.8 With unspecified complications
0.000 0.334 0.666
G31.2 Degeneration of nervous system due to alcohol
0.665 0.335 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.662 0.338 0.000
E13.9 Without complications
0.000 0.340 0.660
G91 Hydrocephalus
0.658 0.342 0.000
G25 Other extrapyramidal and movement disorders
0.658 0.342 0.000
G24 Dystonia
0.645 0.355 0.000
G93.4 Encephalopathy, unspecified
0.643 0.357 0.000
G95 Other diseases of spinal cord
0.643 0.357 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.636 0.363 0.000
G03.9 Meningitis, unspecified
0.621 0.379 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.621 0.379 0.000
G00 Bacterial meningitis, not elsewhere classified
0.617 0.383 0.000
E11.8 With unspecified complications
0.000 0.386 0.614
G98 Other disorders of nervous system, not elsewhere classified
0.603 0.397 0.000
G92 Toxic encephalopathy
0.603 0.397 0.000
G30 Alzheimer's disease
0.597 0.403 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.592 0.408 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.592 0.408 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.592 0.408 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.592 0.408 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.588 0.412 0.000
G37.5 Concentric sclerosis [Balo]
0.587 0.413 0.000
G37.4 Subacute necrotising myelitis
0.587 0.413 0.000
G37.2 Central pontine myelinolysis
0.587 0.413 0.000
G37.1 Central demyelination of corpus callosum
0.587 0.413 0.000
G37.0 Diffuse sclerosis
0.587 0.413 0.000
G83 Other paralytic syndromes
0.584 0.416 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.580 0.420 0.000
E13.8 With unspecified complications
0.000 0.425 0.575
E13.7 With multiple complications
0.000 0.425 0.575
E13.6 With other specified complications
0.000 0.425 0.575
E13.5 With peripheral circulatory complications
0.000 0.425 0.575
E13.4 With neurological complications
0.000 0.425 0.575
E13.3 With ophthalmic complications
0.000 0.425 0.575
E13.2 With renal complications
0.000 0.425 0.575
E13.1 With ketoacidosis
0.000 0.425 0.575
E13.0 With coma
0.000 0.425 0.575
G23 Other degenerative diseases of basal ganglia
0.574 0.426 0.000
G21 Secondary Parkinsonism
0.574 0.426 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.574 0.426 0.000
G22 Parkinsonism in diseases classified elsewhere
0.574 0.426 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.570 0.430 0.000
E83 Disorders of mineral metabolism
0.537 0.431 0.032
G95.0 Syringomyelia and syringobulbia
0.560 0.440 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.556 0.444 0.000
G31.0 Circumscribed brain atrophy
0.556 0.444 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.546 0.454 0.000
G91.1 Obstructive hydrocephalus
0.545 0.455 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.545 0.455 0.000
E11.3 With ophthalmic complications
0.000 0.464 0.536
G06.1 Intraspinal abscess and granuloma
0.534 0.466 0.000
G90 Disorders of autonomic nervous system
0.534 0.466 0.000
G82 Paraplegia and tetraplegia
0.533 0.467 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.529 0.471 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.529 0.471 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.529 0.471 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.527 0.473 0.000
G93.8 Other specified disorders of brain
0.526 0.474 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.524 0.476 0.000
G24.8 Other dystonia
0.522 0.478 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.522 0.478 0.000
G95.2 Cord compression, unspecified
0.518 0.482 0.000
G93.6 Cerebral oedema
0.514 0.486 0.000
G96.0 Cerebrospinal fluid leak
0.514 0.486 0.000
E12.9 Without complications
0.000 0.486 0.513
E12.8 With unspecified complications
0.000 0.486 0.513
E12.7 With multiple complications
0.000 0.486 0.513
E12.6 With other specified complications
0.000 0.486 0.513
E12.5 With peripheral circulatory complications
0.000 0.486 0.513
E12.4 With neurological complications
0.000 0.486 0.513
E12.3 With ophthalmic complications
0.000 0.486 0.513
E12.2 With renal complications
0.000 0.486 0.513
E12.1 With ketoacidosis
0.000 0.486 0.513
E12.0 With coma
0.000 0.486 0.513
G03.8 Meningitis due to other specified causes
0.507 0.493 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.507 0.493 0.000
G03.1 Chronic meningitis
0.507 0.493 0.000
G03.0 Nonpyogenic meningitis
0.507 0.493 0.000
G70-G73 Diseases of myoneural junction and muscle
0.505 0.495 0.000
G93.5 Compression of brain
0.490 0.510 0.000
G06.0 Intracranial abscess and granuloma
0.489 0.511 0.000
G36.9 Acute disseminated demyelination, unspecified
0.489 0.511 0.000
G36.8 Other specified acute disseminated demyelination
0.489 0.511 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.489 0.511 0.000
G36.0 Neuromyelitis optica [Devic]
0.489 0.511 0.000
G30.0 Alzheimer's disease with early onset
0.488 0.512 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.487 0.513 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.485 0.515 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.485 0.515 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.485 0.515 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.483 0.516 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.483 0.516 0.000
E83.5 Disorders of calcium metabolism
0.479 0.517 0.004
G96.9 Disorder of central nervous system, unspecified
0.481 0.519 0.000
G96.8 Other specified disorders of central nervous system
0.481 0.519 0.000
G97.8 Other postprocedural disorders of nervous system
0.480 0.520 0.000
G93.7 Reye's syndrome
0.480 0.520 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.476 0.524 0.000
G24.5 Blepharospasm
0.476 0.524 0.000
G06.2 Extradural and subdural abscess, unspecified
0.474 0.525 0.000
G91.8 Other hydrocephalus
0.472 0.528 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.472 0.528 0.000
G91.2 Normal-pressure hydrocephalus
0.472 0.528 0.000
G91.0 Communicating hydrocephalus
0.472 0.528 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.472 0.528 0.000
G25.5 Other chorea
0.472 0.528 0.000
G25.4 Drug-induced chorea
0.472 0.528 0.000
G25.2 Other specified forms of tremor
0.472 0.528 0.000
G25.1 Drug-induced tremor
0.472 0.528 0.000
G83.8 Other specified paralytic syndromes
0.472 0.528 0.000
G00.1 Pneumococcal meningitis
0.468 0.532 0.000
G24.9 Dystonia, unspecified
0.465 0.535 0.000
G82.1 Spastic paraplegia
0.464 0.536 0.000
G94.1 Hydrocephalus in neoplastic disease
0.464 0.536 0.000
G24.4 Idiopathic orofacial dystonia
0.462 0.538 0.000
G24.3 Spasmodic torticollis
0.462 0.538 0.000
G24.2 Idiopathic nonfamilial dystonia
0.462 0.538 0.000
G24.1 Idiopathic familial dystonia
0.462 0.538 0.000
G24.0 Drug-induced dystonia
0.462 0.538 0.000
G83.9 Paralytic syndrome, unspecified
0.460 0.540 0.000
G83.1 Monoplegia of lower limb
0.446 0.554 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.445 0.555 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.445 0.555 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.445 0.555 0.000
G91.9 Hydrocephalus, unspecified
0.443 0.557 0.000
G00.8 Other bacterial meningitis
0.442 0.558 0.000
G00.3 Staphylococcal meningitis
0.442 0.558 0.000
G00.2 Streptococcal meningitis
0.442 0.558 0.000
G00.0 Haemophilus meningitis
0.442 0.558 0.000
G00.9 Bacterial meningitis, unspecified
0.441 0.559 0.000
L40-L45 Papulosquamous disorders
0.000 0.559 0.441
G40-G47 Episodic and paroxysmal disorders
0.440 0.560 0.000
G80 Infantile cerebral palsy
0.436 0.564 0.000
G83.4 Cauda equina syndrome
0.431 0.569 0.000
G95.1 Vascular myelopathies
0.430 0.570 0.000
G30.8 Other Alzheimer's disease
0.428 0.572 0.000
G30.1 Alzheimer's disease with late onset
0.428 0.572 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.425 0.575 0.000
G02.1 Meningitis in mycoses
0.425 0.575 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.425 0.575 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.421 0.578 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.421 0.578 0.000
G83.5 Locked-in syndrome
0.419 0.581 0.000
G83.3 Monoplegia, unspecified
0.419 0.581 0.000
G83.2 Monoplegia of upper limb
0.419 0.581 0.000
G83.0 Diplegia of upper limbs
0.419 0.581 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.416 0.584 0.000
G21.9 Secondary Parkinsonism, unspecified
0.412 0.588 0.000
G21.8 Other secondary Parkinsonism
0.412 0.588 0.000
G21.4 Vascular parkinsonism
0.412 0.588 0.000
G21.3 Postencephalitic Parkinsonism
0.412 0.588 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.412 0.588 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.412 0.588 0.000
G21.0 Malignant neuroleptic syndrome
0.412 0.588 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.412 0.588 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.412 0.588 0.000
G23.3 Multiple system atrophy, cerebellar type
0.412 0.588 0.000
G23.2 Striatonigral degeneration
0.412 0.588 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.412 0.588 0.000
G23.0 Hallervorden-Spatz disease
0.412 0.588 0.000
G95.8 Other specified diseases of spinal cord
0.411 0.588 0.000
G25.3 Myoclonus
0.411 0.589 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.385 0.592 0.023
E83.8 Other disorders of mineral metabolism
0.385 0.592 0.023
E83.2 Disorders of zinc metabolism
0.385 0.592 0.023
E83.0 Disorders of copper metabolism
0.385 0.592 0.023
G90.3 Multisystem degeneration
0.398 0.602 0.000
G93.2 Benign intracranial hypertension
0.393 0.606 0.000
G25.0 Essential tremor
0.393 0.607 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.391 0.608 0.000
G14 Postpolio syndrome
0.391 0.608 0.000
G10 Huntington's disease
0.391 0.608 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.391 0.609 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.391 0.609 0.000
G04.1 Tropical spastic paraplegia
0.391 0.609 0.000
G04.0 Acute disseminated encephalitis
0.391 0.609 0.000
G11 Hereditary ataxia
0.388 0.611 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.388 0.612 0.000
G40 Epilepsy
0.385 0.615 0.000
G93.9 Disorder of brain, unspecified
0.384 0.616 0.000
G90.8 Other disorders of autonomic nervous system
0.383 0.617 0.000
G90.4 Autonomic dysreflexia
0.383 0.617 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.383 0.617 0.000
G82.4 Spastic tetraplegia
0.382 0.618 0.000
G82.3 Flaccid tetraplegia
0.382 0.618 0.000
G82.0 Flaccid paraplegia
0.382 0.618 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.004 0.622 0.374
G31.8 Other specified degenerative diseases of nervous system
0.377 0.622 0.000
G82.2 Paraplegia, unspecified
0.368 0.632 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.365 0.634 0.000
G72 Other myopathies
0.365 0.635 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.362 0.638 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.357 0.643 0.000
E83.3 Disorders of phosphorus metabolism
0.332 0.646 0.022
G30.9 Alzheimer's disease, unspecified
0.349 0.651 0.000
L43 Lichen planus
0.000 0.652 0.348
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.343 0.656 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.343 0.657 0.000
G81 Hemiplegia
0.342 0.658 0.000
G95.9 Disease of spinal cord, unspecified
0.340 0.659 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.335 0.665 0.000
J45.9 Asthma, unspecified
0.000 0.668 0.332
G82.5 Tetraplegia, unspecified
0.332 0.668 0.000
G70 Myasthenia gravis and other myoneural disorders
0.330 0.670 0.000
K90.0 Coeliac disease
0.000 0.680 0.320
G93.0 Cerebral cysts
0.319 0.681 0.000
G41 Status epilepticus
0.318 0.682 0.000
L44 Other papulosquamous disorders
0.000 0.684 0.316
L41 Parapsoriasis
0.000 0.684 0.316
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.684 0.316
G80.8 Other infantile cerebral palsy
0.312 0.687 0.000
G80.4 Ataxic cerebral palsy
0.312 0.687 0.000
G80.3 Dyskinetic cerebral palsy
0.312 0.687 0.000
G80.2 Infantile hemiplegia
0.312 0.687 0.000
G80.1 Spastic diplegia
0.312 0.687 0.000
G80.0 Spastic cerebral palsy
0.312 0.687 0.000
G43 Migraine
0.312 0.688 0.000
G46.7 Other lacunar syndromes
0.312 0.688 0.000
G12 Spinal muscular atrophy and related syndromes
0.311 0.689 0.000
E83.4 Disorders of magnesium metabolism
0.289 0.690 0.020
E78.2 Mixed hyperlipidaemia
0.002 0.693 0.305
G40.8 Other epilepsy
0.304 0.696 0.000
E70-E90 Metabolic disorders
0.047 0.697 0.256
G93.3 Postviral fatigue syndrome
0.298 0.702 0.000
L42 Pityriasis rosea
0.000 0.703 0.297
G90.2 Horner's syndrome
0.295 0.705 0.000
E78.1 Pure hyperglyceridaemia
0.003 0.709 0.289
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.289 0.711 0.000
G71 Primary disorders of muscles
0.281 0.718 0.000
L43.9 Lichen planus, unspecified
0.000 0.719 0.281
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.281 0.719 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.281 0.719 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.281 0.719 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.281 0.719 0.000
G11.8 Other hereditary ataxias
0.278 0.721 0.000
G11.4 Hereditary spastic paraplegia
0.278 0.721 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.278 0.721 0.000
G11.2 Late-onset cerebellar ataxia
0.278 0.721 0.000
G11.1 Early-onset cerebellar ataxia
0.278 0.721 0.000
G11.0 Congenital nonprogressive ataxia
0.278 0.721 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.276 0.724 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.276 0.724 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.276 0.724 0.000
G11.9 Hereditary ataxia, unspecified
0.276 0.724 0.000
G44 Other headache syndromes
0.275 0.725 0.000
E78.6 Lipoprotein deficiency
0.003 0.729 0.268
E78.3 Hyperchylomicronaemia
0.003 0.729 0.268
Chapter IV Endocrine, nutritional and metabolic diseases
0.009 0.729 0.263
G80.9 Infantile cerebral palsy, unspecified
0.264 0.735 0.000
G72.9 Myopathy, unspecified
0.264 0.735 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.262 0.738 0.000
G46.6 Pure sensory lacunar syndrome
0.262 0.738 0.000
G46.5 Pure motor lacunar syndrome
0.262 0.738 0.000
G46.4 Cerebellar stroke syndrome
0.262 0.738 0.000
G46.3 Brain stem stroke syndrome
0.262 0.738 0.000
G46.2 Posterior cerebral artery syndrome
0.262 0.738 0.000
G46.1 Anterior cerebral artery syndrome
0.262 0.738 0.000
G46.0 Middle cerebral artery syndrome
0.262 0.738 0.000
G72.8 Other specified myopathies
0.262 0.738 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.262 0.738 0.000
G72.3 Periodic paralysis
0.262 0.738 0.000
G72.2 Myopathy due to other toxic agents
0.262 0.738 0.000
G72.1 Alcoholic myopathy
0.262 0.738 0.000
G72.0 Drug-induced myopathy
0.262 0.738 0.000
G73.7 Myopathy other diseases classified elsewhere
0.260 0.740 0.000
G73.6 Myopathy in metabolic diseases
0.260 0.740 0.000
G73.5 Myopathy in endocrine diseases
0.260 0.740 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.260 0.740 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.260 0.740 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.260 0.740 0.000
G73.1 Eaton-Lambert syndrome
0.260 0.740 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.260 0.740 0.000
E78.8 Other disorders of lipoprotein metabolism
0.003 0.741 0.256
E78.4 Other hyperlipidaemia
0.003 0.745 0.252
G43.8 Other migraine
0.254 0.746 0.000
G81.1 Spastic hemiplegia
0.251 0.749 0.000
L43.8 Other lichen planus
0.000 0.750 0.250
L43.3 Subacute (active) lichen planus
0.000 0.750 0.250
L43.2 Lichenoid drug reaction
0.000 0.750 0.250
L43.1 Bullous lichen planus
0.000 0.750 0.250
L43.0 Hypertrophic lichen planus
0.000 0.750 0.250
G40.5 Special epileptic syndromes
0.247 0.753 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.245 0.754 0.001
G81.0 Flaccid hemiplegia
0.245 0.755 0.000
G43.0 Migraine without aura [common migraine]
0.242 0.758 0.000
K90 Intestinal malabsorption
0.000 0.761 0.239
G41.0 Grand mal status epilepticus
0.237 0.763 0.000
G70.9 Myoneural disorder, unspecified
0.237 0.763 0.000
G70.8 Other specified myoneural disorders
0.237 0.763 0.000
G70.2 Congenital and developmental myasthenia
0.237 0.763 0.000
G70.1 Toxic myoneural disorders
0.237 0.763 0.000
G41.8 Other status epilepticus
0.228 0.772 0.000
G41.2 Complex partial status epilepticus
0.228 0.772 0.000
G41.1 Petit mal status epilepticus
0.228 0.772 0.000
L41.9 Parapsoriasis, unspecified
0.000 0.773 0.227
L41.8 Other parapsoriasis
0.000 0.773 0.227
L41.5 Retiform parapsoriasis
0.000 0.773 0.227
L41.4 Large plaque parapsoriasis
0.000 0.773 0.227
L41.3 Small plaque parapsoriasis
0.000 0.773 0.227
L41.2 Lymphomatoid papulosis
0.000 0.773 0.227
L41.1 Pityriasis lichenoides chronica
0.000 0.773 0.227
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.773 0.227
L44.9 Papulosquamous disorder, unspecified
0.000 0.773 0.227
L44.8 Other specified papulosquamous disorders
0.000 0.773 0.227
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.773 0.227
L44.3 Lichen ruber moniliformis
0.000 0.773 0.227
L44.2 Lichen striatus
0.000 0.773 0.227
L44.1 Lichen nitidus
0.000 0.773 0.227
L44.0 Pityriasis rubra pilaris
0.000 0.773 0.227
E78.9 Disorder of lipoprotein metabolism, unspecified
0.003 0.775 0.222
G43.3 Complicated migraine
0.224 0.776 0.000
G43.2 Status migrainosus
0.224 0.776 0.000
G12.9 Spinal muscular atrophy, unspecified
0.223 0.777 0.000
G12.8 Other spinal muscular atrophies and related syndromes
0.223 0.777 0.000
G12.1 Other inherited spinal muscular atrophy
0.223 0.777 0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.223 0.777 0.000
E85 Amyloidosis
0.029 0.777 0.194
G41.9 Status epilepticus, unspecified
0.220 0.779 0.000
E74 Other disorders of carbohydrate metabolism
0.032 0.780 0.188
G43.1 Migraine with aura [classical migraine]
0.217 0.783 0.000
E84 Cystic fibrosis
0.034 0.783 0.183
E79 Disorders of purine and pyrimidine metabolism
0.034 0.783 0.183
E77 Disorders of glycoprotein metabolism
0.034 0.783 0.183
E76 Disorders of glycosaminoglycan metabolism
0.034 0.783 0.183
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.034 0.783 0.183
E72 Other disorders of amino-acid metabolism
0.034 0.783 0.183
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.034 0.783 0.183
E70 Disorders of aromatic amino-acid metabolism
0.034 0.783 0.183
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.034 0.783 0.183
G44.0 Cluster headache syndrome
0.213 0.786 0.000
E73 Lactose intolerance
0.033 0.791 0.176
K90.9 Intestinal malabsorption, unspecified
0.000 0.792 0.208
G70.0 Myasthenia gravis
0.204 0.795 0.000
G71.9 Primary disorder of muscle, unspecified
0.202 0.798 0.000
G71.8 Other primary disorders of muscles
0.202 0.798 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.202 0.798 0.000
G71.2 Congenital myopathies
0.202 0.798 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.801 0.199
G44.4 Drug-induced headache, not elsewhere classified
0.197 0.803 0.000
G44.3 Chronic posttraumatic headache
0.197 0.803 0.000
G44.1 Vascular headache, not elsewhere classified
0.197 0.803 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.005 0.803 0.192
E88 Other metabolic disorders
0.032 0.805 0.163
E40-E46 Malnutrition
0.006 0.818 0.175
G64 Other disorders of peripheral nervous system
0.176 0.824 0.001
E80 Disorders of porphyrin and bilirubin metabolism
0.037 0.824 0.139
G44.8 Other specified headache syndromes
0.174 0.825 0.000
K90.8 Other intestinal malabsorption
0.000 0.829 0.171
K90.3 Pancreatic steatorrhoea
0.000 0.829 0.171
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.829 0.171
K90.1 Tropical sprue
0.000 0.829 0.171
G60 Hereditary and idiopathic neuropathy
0.170 0.829 0.001
G71.1 Myotonic disorders
0.170 0.829 0.001
E85.9 Amyloidosis, unspecified
0.018 0.830 0.152
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.169 0.830 0.000
G71.0 Muscular dystrophy
0.167 0.832 0.001
G47 Sleep disorders
0.162 0.838 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.021 0.839 0.140
E85.8 Other amyloidosis
0.021 0.840 0.139
E85.3 Secondary systemic amyloidosis
0.021 0.840 0.139
E85.2 Heredofamilial amyloidosis, unspecified
0.021 0.840 0.139
E85.1 Neuropathic heredofamilial amyloidosis
0.021 0.840 0.139
E85.0 Nonneuropathic heredofamilial amyloidosis
0.021 0.840 0.139
E20-E35 Disorders of other endocrine glands
0.004 0.841 0.155
G44.2 Tension-type headache
0.158 0.842 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.023 0.842 0.135
E74.8 Other specified disorders of carbohydrate metabolism
0.023 0.842 0.135
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.023 0.842 0.135
E74.2 Disorders of galactose metabolism
0.023 0.842 0.135
E74.1 Disorders of fructose metabolism
0.023 0.842 0.135
E74.0 Glycogen storage disease
0.023 0.842 0.135
G40.9 Epilepsy, unspecified
0.158 0.842 0.000
E85.4 Organ-limited amyloidosis
0.020 0.844 0.136
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.024 0.844 0.132
E70.8 Other disorders of aromatic amino-acid metabolism
0.024 0.844 0.132
E70.3 Albinism
0.024 0.844 0.132
E70.2 Disorders of tyrosine metabolism
0.024 0.844 0.132
E70.1 Other hyperphenylalaninaemias
0.024 0.844 0.132
E70.0 Classical phenylketonuria
0.024 0.844 0.132
E71.3 Disorders of fatty-acid metabolism
0.024 0.844 0.132
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.024 0.844 0.132
E71.1 Other disorders of branched-chain amino-acid metabolism
0.024 0.844 0.132
E71.0 Maple-syrup-urine disease
0.024 0.844 0.132
E72.9 Disorder of amino-acid metabolism, unspecified
0.024 0.844 0.132
E72.8 Other specified disorders of amino-acid metabolism
0.024 0.844 0.132
E72.5 Disorders of glycine metabolism
0.024 0.844 0.132
E72.4 Disorders of ornithine metabolism
0.024 0.844 0.132
E72.3 Disorders of lysine and hydroxylysine metabolism
0.024 0.844 0.132
E72.2 Disorders of urea cycle metabolism
0.024 0.844 0.132
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.024 0.844 0.132
E72.0 Disorders of amino-acid transport
0.024 0.844 0.132
E75.6 Lipid storage disorder, unspecified
0.024 0.844 0.132
E75.5 Other lipid storage disorders
0.024 0.844 0.132
E75.4 Neuronal ceroid lipofuscinosis
0.024 0.844 0.132
E75.3 Sphingolipidosis, unspecified
0.024 0.844 0.132
E75.2 Other sphingolipidosis
0.024 0.844 0.132
E75.1 Other gangliosidosis
0.024 0.844 0.132
E75.0 GM2 gangliosidosis
0.024 0.844 0.132
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.024 0.844 0.132
E76.8 Other disorders of glucosaminoglycan metabolism
0.024 0.844 0.132
E76.3 Mucopolysaccharidosis, unspecified
0.024 0.844 0.132
E76.2 Other mucopolysaccharidoses
0.024 0.844 0.132
E76.1 Mucopolysaccharidosis, type II
0.024 0.844 0.132
E76.0 Mucopolysaccharidosis, type I
0.024 0.844 0.132
E77.9 Disorder of glycoprotein metabolism, unspecified
0.024 0.844 0.132
E77.8 Other disorders of glycoprotein metabolism
0.024 0.844 0.132
E77.1 Defects in glycoprotein degradation
0.024 0.844 0.132
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.024 0.844 0.132
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.024 0.844 0.132
E79.8 Other disorders of purine and pyrimidine metabolism
0.024 0.844 0.132
E79.1 Lesch-Nyhan syndrome
0.024 0.844 0.132
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.024 0.844 0.132
E84.9 Cystic fibrosis, unspecified
0.024 0.844 0.132
E84.8 Cystic fibrosis with other manifestations
0.024 0.844 0.132
E84.1 Cystic fibrosis with intestinal manifestations
0.024 0.844 0.132
E84.0 Cystic fibrosis with pulmonary manifestations
0.024 0.844 0.132
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.043 0.846 0.111
G43.9 Migraine, unspecified
0.151 0.849 0.000
E73.8 Other lactose intolerance
0.024 0.850 0.127
E73.1 Secondary lactase deficiency
0.024 0.850 0.127
E73.0 Congenital lactase deficiency
0.024 0.850 0.127
E50-E64 Other nutritional deficiencies
0.006 0.850 0.144
E16 Other disorders of pancreatic internal secretion
0.002 0.856 0.141
G12.2 Motor neuron disease
0.143 0.857 0.001
G60.8 Other hereditary and idiopathic neuropathies
0.142 0.857 0.001
E73.9 Lactose intolerance, unspecified
0.023 0.857 0.119
E15 Nondiabetic hypoglycaemic coma
0.004 0.858 0.138
E88.9 Metabolic disorder, unspecified
0.023 0.860 0.117
E88.8 Other specified metabolic disorders
0.023 0.860 0.117
E88.3 Tumour lysis syndrome
0.023 0.860 0.117
E88.2 Lipomatosis, not elsewhere classified
0.023 0.860 0.117
E88.1 Lipodystrophy, not elsewhere classified
0.023 0.860 0.117
G61 Inflammatory polyneuropathy
0.136 0.863 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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