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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130283
log Bayes Factor = 157.559
Chromosome 6   position 32,138,545  (GRCh37) Explore rs3130283 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.001 0.999
L43 Lichen planus
0.000 0.001 0.999
L43.9 Lichen planus, unspecified
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K51.9 Ulcerative colitis, unspecified
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.002 0.998
K51 Ulcerative colitis
0.998 0.002 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.002 0.998
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
J45.9 Asthma, unspecified
0.000 0.002 0.998
E14.9 Without complications
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.000 0.004 0.996
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
H43-H45 Disorders of vitreous body and globe
0.000 0.006 0.994
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.006 0.994
I20.0 Unstable angina
0.000 0.006 0.994
I22 Subsequent myocardial infarction
0.000 0.007 0.993
M05 Seropositive rheumatoid arthritis
0.000 0.007 0.993
K70-K77 Diseases of liver
0.000 0.007 0.993
H43 Disorders of vitreous body
0.000 0.007 0.993
I47 Paroxysmal tachycardia
0.000 0.008 0.992
K51.3 Ulcerative (chronic) rectosigmoiditis
0.992 0.008 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.991 0.009 0.000
I35 Nonrheumatic aortic valve disorders
0.000 0.009 0.991
E14.3 With ophthalmic complications
0.000 0.010 0.990
K82 Other diseases of gallbladder
0.000 0.010 0.990
I35.0 Aortic (valve) stenosis
0.000 0.010 0.990
I25.1 Atherosclerotic heart disease
0.000 0.010 0.990
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.010 0.990
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.012 0.988
E70-E90 Metabolic disorders
0.000 0.013 0.986
K74 Fibrosis and cirrhosis of liver
0.000 0.016 0.984
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.016 0.984
J45 Asthma
0.000 0.017 0.983
K82.8 Other specified diseases of gallbladder
0.000 0.020 0.980
I47.1 Supraventricular tachycardia
0.000 0.020 0.980
J40-J47 Chronic lower respiratory diseases
0.000 0.021 0.979
K55-K64 Other diseases of intestines
0.000 0.023 0.977
Chapter X Diseases of the respiratory system
0.000 0.023 0.977
I20.9 Angina pectoris, unspecified
0.000 0.024 0.976
K80 Cholelithiasis
0.000 0.025 0.975
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.026 0.974
K60 Fissure and fistula of anal and rectal regions
0.000 0.026 0.974
K74.3 Primary biliary cirrhosis
0.000 0.027 0.973
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.029 0.971
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.030 0.970
H43.3 Other vitreous opacities
0.000 0.031 0.969
K60.2 Anal fissure, unspecified
0.000 0.032 0.968
K50-K52 Noninfective enteritis and colitis
0.008 0.032 0.959
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.033 0.967
E11.3 With ophthalmic complications
0.000 0.033 0.967
E10.5 With peripheral circulatory complications
0.000 0.033 0.967
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.033 0.967
I25.5 Ischaemic cardiomyopathy
0.000 0.037 0.963
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.043 0.957
H43.8 Other disorders of vitreous body
0.000 0.043 0.957
H34 Retinal vascular occlusions
0.000 0.046 0.954
K81 Cholecystitis
0.000 0.054 0.946
I24 Other acute ischaemic heart diseases
0.000 0.055 0.945
I25.2 Old myocardial infarction
0.000 0.055 0.945
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.055 0.945
E07 Other disorders of thyroid
0.000 0.059 0.941
I12 Hypertensive renal disease
0.000 0.063 0.937
M07 Psoriatic and enteropathic arthropathies
0.000 0.063 0.937
J95-J99 Other diseases of the respiratory system
0.000 0.064 0.936
K50 Crohn's disease [regional enteritis]
0.000 0.064 0.935
H40-H42 Glaucoma
0.000 0.067 0.933
I21 Acute myocardial infarction
0.000 0.074 0.926
K51.8 Other ulcerative colitis
0.922 0.078 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.079 0.921
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.092 0.908
I31 Other diseases of pericardium
0.000 0.094 0.906
E07.9 Disorder of thyroid, unspecified
0.000 0.094 0.906
K72 Hepatic failure, not elsewhere classified
0.000 0.097 0.903
K81.1 Chronic cholecystitis
0.000 0.098 0.902
I20.1 Angina pectoris with documented spasm
0.000 0.099 0.901
K60.0 Acute anal fissure
0.000 0.099 0.901
E10.2 With renal complications
0.000 0.102 0.898
I46 Cardiac arrest
0.000 0.103 0.897
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.104 0.896
J46 Status asthmaticus
0.000 0.104 0.896
E11.2 With renal complications
0.000 0.105 0.895
K82.1 Hydrops of gallbladder
0.000 0.107 0.893
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.108 0.892
M07.3 Other psoriatic arthropathies
0.000 0.108 0.892
K81.9 Cholecystitis, unspecified
0.000 0.109 0.891
J98 Other respiratory disorders
0.000 0.110 0.890
G37.8 Other specified demyelinating diseases of central nervous system
0.887 0.113 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.114 0.886
H40 Glaucoma
0.000 0.114 0.886
H40.9 Glaucoma, unspecified
0.000 0.114 0.886
K63 Other diseases of intestine
0.000 0.114 0.886
K55 Vascular disorders of intestine
0.000 0.114 0.886
E03.8 Other specified hypothyroidism
0.000 0.119 0.881
K58 Irritable bowel syndrome
0.000 0.121 0.879
K51.2 Ulcerative (chronic) proctitis
0.876 0.124 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.124 0.876
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.125 0.875
E05.9 Thyrotoxicosis, unspecified
0.000 0.125 0.875
E11.1 With ketoacidosis
0.000 0.126 0.874
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.127 0.873
E83 Disorders of mineral metabolism
0.832 0.129 0.039
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.133 0.867
H34.2 Other retinal artery occlusions
0.000 0.134 0.866
M06.3 Rheumatoid nodule
0.000 0.139 0.861
E13 Other specified diabetes mellitus
0.000 0.139 0.861
Chapter VIII Diseases of the ear and mastoid process
0.000 0.142 0.858
I47.2 Ventricular tachycardia
0.000 0.142 0.858
J43 Emphysema
0.000 0.143 0.857
I12.9 Hypertensive renal disease without renal failure
0.000 0.145 0.855
K63.9 Disease of intestine, unspecified
0.000 0.146 0.854
K75 Other inflammatory liver diseases
0.000 0.146 0.854
J44 Other chronic obstructive pulmonary disease
0.000 0.149 0.851
I31.3 Pericardial effusion (noninflammatory)
0.000 0.151 0.849
I46.9 Cardiac arrest, unspecified
0.000 0.153 0.847
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.155 0.845
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.158 0.842
J98.4 Other disorders of lung
0.000 0.158 0.842
H43.1 Vitreous haemorrhage
0.000 0.158 0.842
E11.5 With peripheral circulatory complications
0.000 0.159 0.841
I21.9 Acute myocardial infarction, unspecified
0.000 0.159 0.841
K50.8 Other Crohn's disease
0.000 0.162 0.838
M06.4 Inflammatory polyarthropathy
0.000 0.163 0.837
K50.0 Crohn's disease of small intestine
0.000 0.164 0.836
H34.8 Other retinal vascular occlusions
0.000 0.165 0.835
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.167 0.833
I15 Secondary hypertension
0.000 0.168 0.832
K50.9 Crohn's disease, unspecified
0.000 0.168 0.832
K51.5 Mucosal proctocolitis
0.831 0.169 0.000
I47.0 Reentry ventricular arrhythmia
0.000 0.170 0.830
K73 Chronic hepatitis, not elsewhere classified
0.000 0.172 0.828
E06 Thyroiditis
0.000 0.173 0.827
K60.5 Anorectal fistula
0.000 0.174 0.826
I21.4 Acute subendocardial myocardial infarction
0.000 0.176 0.824
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.178 0.822
J86 Pyothorax
0.000 0.181 0.819
K74.6 Other and unspecified cirrhosis of liver
0.000 0.182 0.818
K55.2 Angiodysplasia of colon
0.000 0.185 0.815
E11.0 With coma
0.000 0.190 0.810
E16.1 Other hypoglycaemia
0.000 0.192 0.808
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.195 0.805
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.195 0.805
I51 Complications and ill-defined descriptions of heart disease
0.000 0.198 0.802
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.198 0.802
H65-H75 Diseases of middle ear and mastoid
0.000 0.199 0.801
L43.8 Other lichen planus
0.000 0.200 0.799
K72.9 Hepatic failure, unspecified
0.000 0.202 0.798
H60-H62 Diseases of external ear
0.000 0.202 0.798
I25.3 Aneurysm of heart
0.000 0.203 0.796
K80.8 Other cholelithiasis
0.000 0.207 0.793
I12.0 Hypertensive renal disease with renal failure
0.000 0.208 0.792
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.792 0.208 0.000
E83.3 Disorders of phosphorus metabolism
0.779 0.211 0.009
H43.9 Disorder of vitreous body, unspecified
0.000 0.212 0.788
E11.6 With other specified complications
0.000 0.215 0.785
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.218 0.782
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.219 0.781
K55.8 Other vascular disorders of intestine
0.000 0.220 0.780
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.220 0.780
K74.5 Biliary cirrhosis, unspecified
0.000 0.221 0.779
I51.8 Other ill-defined heart diseases
0.000 0.222 0.778
M65-M68 Disorders of synovium and tendon
0.000 0.222 0.778
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.223 0.777
M06.0 Seronegative rheumatoid arthritis
0.000 0.230 0.770
K82.9 Disease of gallbladder, unspecified
0.000 0.233 0.767
H71 Cholesteatoma of middle ear
0.000 0.235 0.765
E13.9 Without complications
0.000 0.239 0.761
E40-E46 Malnutrition
0.000 0.240 0.760
L40.8 Other psoriasis
0.000 0.241 0.759
I25.4 Coronary artery aneurysm
0.000 0.245 0.755
M11 Other crystal arthropathies
0.000 0.246 0.754
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.248 0.752
E74 Other disorders of carbohydrate metabolism
0.000 0.248 0.752
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.249 0.751
K51.0 Ulcerative (chronic) enterocolitis
0.749 0.251 0.000
I23 Certain current complications following acute myocardial infarction
0.000 0.255 0.745
K72.0 Acute and subacute hepatic failure
0.000 0.256 0.744
K51.4 Pseudopolyposis of colon
0.743 0.257 0.000
I35.8 Other aortic valve disorders
0.000 0.258 0.742
M06.34 Rheumatoid nodule (Hand)
0.000 0.263 0.737
H30 Chorioretinal inflammation
0.000 0.266 0.734
E88 Other metabolic disorders
0.000 0.266 0.734
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.266 0.734
J43.2 Centrilobular emphysema
0.000 0.267 0.733
K75.4 Autoimmune hepatitis
0.000 0.268 0.732
E06.3 Autoimmune thyroiditis
0.000 0.269 0.731
E78.8 Other disorders of lipoprotein metabolism
0.000 0.269 0.731
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.270 0.730
L40.0 Psoriasis vulgaris
0.000 0.270 0.729
I30 Acute pericarditis
0.000 0.271 0.729
K82.2 Perforation of gallbladder
0.000 0.273 0.727
K63.3 Ulcer of intestine
0.000 0.273 0.727
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.274 0.726
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.275 0.725
K82.3 Fistula of gallbladder
0.000 0.277 0.723
H34.1 Central retinal artery occlusion
0.000 0.277 0.723
E78.2 Mixed hyperlipidaemia
0.000 0.278 0.722
K63.4 Enteroptosis
0.000 0.280 0.720
J86.9 Pyothorax without fistula
0.000 0.282 0.718
E78.4 Other hyperlipidaemia
0.000 0.282 0.718
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
J98.6 Disorders of diaphragm
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
L43.3 Subacute (active) lichen planus
0.000 0.283 0.716
L43.2 Lichenoid drug reaction
0.000 0.283 0.716
L43.1 Bullous lichen planus
0.000 0.283 0.716
L43.0 Hypertrophic lichen planus
0.000 0.283 0.716
M65 Synovitis and tenosynovitis
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
K63.2 Fistula of intestine
0.000 0.284 0.716
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.284 0.716
K90.9 Intestinal malabsorption, unspecified
0.000 0.285 0.715
G36 Other acute disseminated demyelination
0.714 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.000 0.286 0.714
I48 Atrial fibrillation and flutter
0.000 0.286 0.714
I41 Myocarditis in diseases classified elsewhere
0.000 0.286 0.714
I40 Acute myocarditis
0.000 0.286 0.714
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.286 0.714
I32 Pericarditis in diseases classified elsewhere
0.000 0.286 0.714
G37.5 Concentric sclerosis [Balo]
0.713 0.287 0.000
G37.4 Subacute necrotising myelitis
0.713 0.287 0.000
G37.2 Central pontine myelinolysis
0.713 0.287 0.000
G37.1 Central demyelination of corpus callosum
0.713 0.287 0.000
G37.0 Diffuse sclerosis
0.713 0.287 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.287 0.713
I11 Hypertensive heart disease
0.000 0.287 0.713
M05.8 Other seropositive rheumatoid arthritis
0.000 0.288 0.712
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.288 0.712
M05.2 Rheumatoid vasculitis
0.000 0.288 0.712
M05.1 Rheumatoid lung disease
0.000 0.288 0.712
M05.0 Felty's syndrome
0.000 0.288 0.712
K77 Liver disorders in diseases classified elsewhere
0.000 0.288 0.712
K71 Toxic liver disease
0.000 0.288 0.712
H43.2 Crystalline deposits in vitreous body
0.000 0.288 0.712
H43.0 Vitreous prolapse
0.000 0.288 0.712
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.290 0.709
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.290 0.709
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.290 0.709
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.290 0.709
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.290 0.709
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.290 0.709
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.290 0.709
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.290 0.709
H66 Suppurative and unspecified otitis media
0.000 0.291 0.709
E78.6 Lipoprotein deficiency
0.000 0.291 0.709
E78.3 Hyperchylomicronaemia
0.000 0.291 0.709
E83.9 Disorder of mineral metabolism, unspecified
0.686 0.292 0.023
E78.1 Pure hyperglyceridaemia
0.000 0.292 0.708
E77 Disorders of glycoprotein metabolism
0.000 0.293 0.707
E76 Disorders of glycosaminoglycan metabolism
0.000 0.293 0.707
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.293 0.707
E72 Other disorders of amino-acid metabolism
0.000 0.293 0.707
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.293 0.707
E70 Disorders of aromatic amino-acid metabolism
0.000 0.293 0.707
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.293 0.707
K74.4 Secondary biliary cirrhosis
0.000 0.294 0.706
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.294 0.706
K74.1 Hepatic sclerosis
0.000 0.294 0.706
J45.8 Mixed asthma
0.000 0.295 0.705
J45.1 Nonallergic asthma
0.000 0.295 0.705
H61 Other disorders of external ear
0.000 0.295 0.705
E11.8 With unspecified complications
0.000 0.297 0.702
K52 Other non-infective gastro-enteritis and colitis
0.001 0.298 0.701
J41 Simple and mucopurulent chronic bronchitis
0.000 0.298 0.702
K51.1 Ulcerative (chronic) ileocolitis
0.702 0.298 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.300 0.700
K80.3 Calculus of bile duct with cholangitis
0.000 0.301 0.699
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.301 0.699
H66.3 Other chronic suppurative otitis media
0.000 0.301 0.699
J86.0 Pyothorax with fistula
0.000 0.301 0.698
H60 Otitis externa
0.000 0.308 0.692
E79 Disorders of purine and pyrimidine metabolism
0.000 0.308 0.692
I45 Other conduction disorders
0.000 0.309 0.691
I15.1 Hypertension secondary to other renal disorders
0.000 0.310 0.689
K55.1 Chronic vascular disorders of intestine
0.000 0.314 0.686
L42 Pityriasis rosea
0.000 0.314 0.685
J43.9 Emphysema, unspecified
0.000 0.314 0.686
J85 Abscess of lung and mediastinum
0.000 0.315 0.685
H34.9 Retinal vascular occlusion, unspecified
0.000 0.316 0.684
H34.0 Transient retinal artery occlusion
0.000 0.316 0.684
I36 Nonrheumatic tricuspid valve disorders
0.000 0.318 0.682
I05-I09 Chronic rheumatic heart diseases
0.000 0.319 0.681
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.323 0.677
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.323 0.677
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.323 0.677
E07.1 Dyshormogenetic goitre
0.000 0.326 0.674
E07.0 Hypersecretion of calcitonin
0.000 0.326 0.674
M14 Arthropathies in other diseases classified elsewhere
0.000 0.326 0.674
H74 Other disorders of middle ear and mastoid
0.000 0.326 0.674
E11.4 With neurological complications
0.000 0.327 0.673
K82.0 Obstruction of gallbladder
0.000 0.327 0.673
I31.9 Disease of pericardium, unspecified
0.000 0.328 0.672
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.328 0.672
M07.6 Other enteropathic arthropathies
0.000 0.328 0.671
M07.5 Arthropathy in ulcerative colitis
0.000 0.328 0.671
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.328 0.671
M07.2 Psoriatic spondylitis
0.000 0.328 0.671
M07.1 Arthritis mutilans
0.000 0.328 0.671
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.328 0.671
J96 Respiratory failure, not elsewhere classified
0.000 0.329 0.671
H42 Glaucoma in diseases classified elsewhere
0.000 0.331 0.669
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.334 0.666
K73.9 Chronic hepatitis, unspecified
0.000 0.335 0.665
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.335 0.665
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.335 0.664
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.336 0.664
E84 Cystic fibrosis
0.000 0.342 0.658
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.343 0.657
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.343 0.657
I22.8 Subsequent myocardial infarction of other sites
0.000 0.346 0.654
K60.4 Rectal fistula
0.000 0.347 0.653
K75.8 Other specified inflammatory liver diseases
0.000 0.349 0.651
E05.5 Thyroid crisis or storm
0.000 0.349 0.651
E05.4 Thyrotoxicosis factitia
0.000 0.349 0.651
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.349 0.651
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.349 0.651
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.350 0.650
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.001 0.350 0.649
I31.8 Other specified diseases of pericardium
0.000 0.350 0.650
I31.2 Haemopericardium, not elsewhere classified
0.000 0.350 0.650
I31.0 Chronic adhesive pericarditis
0.000 0.350 0.650
K60.1 Chronic anal fissure
0.000 0.352 0.648
K72.1 Chronic hepatic failure
0.000 0.353 0.647
M12 Other specific arthropathies
0.000 0.355 0.645
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.355 0.645
H53-H54 Visual disturbances and blindness
0.000 0.355 0.645
I46.1 Sudden cardiac death, so described
0.000 0.357 0.643
K75.0 Abscess of liver
0.000 0.357 0.643
K74.0 Hepatic fibrosis
0.000 0.359 0.641
K90.8 Other intestinal malabsorption
0.000 0.359 0.641
M45-M49 Spondylopathies
0.000 0.359 0.641
M07.38 Other psoriatic arthropathies (Other)
0.000 0.360 0.640
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.360 0.640
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.360 0.640
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.360 0.640
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.360 0.640
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.360 0.640
J98.3 Compensatory emphysema
0.000 0.362 0.638
H40.6 Glaucoma secondary to drugs
0.000 0.364 0.635
H40.4 Glaucoma secondary to eye inflammation
0.000 0.364 0.635
H40.3 Glaucoma secondary to eye trauma
0.000 0.364 0.635
I15.9 Seconday hypertension, unspecified
0.000 0.366 0.634
I24.8 Other forms of acute ischaemic heart disease
0.000 0.368 0.632
J42 Unspecified chronic bronchitis
0.000 0.372 0.628
H61.1 Non-infective disorders of pinna
0.000 0.374 0.626
E83.8 Other disorders of mineral metabolism
0.597 0.375 0.028
E83.2 Disorders of zinc metabolism
0.597 0.375 0.028
E83.0 Disorders of copper metabolism
0.597 0.375 0.028
J98.2 Interstitial emphysema
0.000 0.378 0.621
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.380 0.620
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.381 0.619
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.382 0.618
M45 Ankylosing spondylitis
0.000 0.382 0.618
I51.6 Cardiovascular disease, unspecified
0.000 0.382 0.618
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.383 0.617
M06.38 Rheumatoid nodule (Other)
0.000 0.383 0.617
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.383 0.617
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.383 0.617
M06.33 Rheumatoid nodule (Forearm)
0.000 0.383 0.617
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.383 0.617
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.383 0.617
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.383 0.617
E13.8 With unspecified complications
0.000 0.383 0.617
E13.7 With multiple complications
0.000 0.383 0.617
E13.6 With other specified complications
0.000 0.383 0.617
E13.5 With peripheral circulatory complications
0.000 0.383 0.617
E13.4 With neurological complications
0.000 0.383 0.617
E13.3 With ophthalmic complications
0.000 0.383 0.617
E13.2 With renal complications
0.000 0.383 0.617
E13.1 With ketoacidosis
0.000 0.383 0.617
E13.0 With coma
0.000 0.383 0.617
I24.1 Dressler's syndrome
0.000 0.384 0.616
E07.8 Other specified disorders of thyroid
0.000 0.385 0.615
I37 Pulmonary valve disorders
0.000 0.385 0.615
J43.8 Other emphysema
0.000 0.385 0.614
J43.1 Panlobular emphysema
0.000 0.385 0.614
J43.0 MacLeod's syndrome
0.000 0.385 0.614
J95.0 Tracheostomy malfunction
0.000 0.386 0.614
K63.0 Abscess of intestine
0.000 0.386 0.613
I51.0 Cardiac septal defect, acquired
0.000 0.388 0.612
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.388 0.612
K75.2 Nonspecific reactive hepatitis
0.000 0.388 0.612
K75.1 Phlebitis of portal vein
0.000 0.388 0.612
K50.1 Crohn's disease of large intestine
0.000 0.390 0.610
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.391 0.609
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.392 0.608
M70-M79 Other soft tissue disorders
0.000 0.394 0.606
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.396 0.604
H35 Other retinal disorders
0.000 0.399 0.601
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.400 0.600
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.400 0.600
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.400 0.600
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.400 0.600
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.400 0.600
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.400 0.600
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.400 0.600
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.400 0.600
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.400 0.600
H40.5 Glaucoma secondary to other eye disorders
0.000 0.401 0.599
E83.5 Disorders of calcium metabolism
0.593 0.403 0.004
I15.8 Other secondary hypertension
0.000 0.403 0.597
I15.2 Hypertension secondary to endocrine disorders
0.000 0.403 0.597
I15.0 Renovascular hypertension
0.000 0.403 0.597
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.403 0.597
J95.8 Other postprocedural respiratory disorders
0.000 0.404 0.596
K81.8 Other cholecystitis
0.000 0.404 0.596
H40.1 Primary open-angle glaucoma
0.000 0.405 0.595
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.406 0.593
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.406 0.593
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.406 0.593
E06.5 Other chronic thyroiditis
0.000 0.407 0.593
E06.4 Drug-induced thyroiditis
0.000 0.407 0.593
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.407 0.593
E06.1 Subacute thyroiditis
0.000 0.407 0.593

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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