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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130342
log Bayes Factor = 152.971
Chromosome 6   position 32,080,146  (GRCh37) Explore rs3130342 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
I20 Angina pectoris
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
J45.9 Asthma, unspecified
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.999 0.001 0.000
K90 Intestinal malabsorption
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.002 0.998
I20.0 Unstable angina
0.000 0.003 0.997
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.000 0.004 0.996
L43 Lichen planus
0.000 0.005 0.995
K70-K77 Diseases of liver
0.000 0.005 0.995
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.006 0.994
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
I47 Paroxysmal tachycardia
0.000 0.007 0.993
I35 Nonrheumatic aortic valve disorders
0.000 0.008 0.992
I35.0 Aortic (valve) stenosis
0.000 0.008 0.992
I25.1 Atherosclerotic heart disease
0.000 0.008 0.992
E14.3 With ophthalmic complications
0.000 0.008 0.992
E70-E90 Metabolic disorders
0.000 0.009 0.991
L43.9 Lichen planus, unspecified
0.000 0.009 0.991
I22 Subsequent myocardial infarction
0.000 0.009 0.991
M05 Seropositive rheumatoid arthritis
0.000 0.013 0.987
H40-H42 Glaucoma
0.000 0.014 0.986
K82 Other diseases of gallbladder
0.000 0.014 0.986
K74 Fibrosis and cirrhosis of liver
0.000 0.015 0.985
K80 Cholelithiasis
0.000 0.016 0.984
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.016 0.984
H43-H45 Disorders of vitreous body and globe
0.000 0.016 0.984
I20.9 Angina pectoris, unspecified
0.000 0.017 0.983
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.017 0.983
I47.1 Supraventricular tachycardia
0.000 0.019 0.981
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.021 0.979
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.021 0.979
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.022 0.978
H43 Disorders of vitreous body
0.000 0.022 0.978
H40 Glaucoma
0.000 0.023 0.977
H40.9 Glaucoma, unspecified
0.000 0.023 0.977
I24 Other acute ischaemic heart diseases
0.000 0.024 0.976
K82.8 Other specified diseases of gallbladder
0.000 0.027 0.973
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.030 0.970
K74.3 Primary biliary cirrhosis
0.000 0.033 0.967
K81 Cholecystitis
0.000 0.037 0.963
E10.5 With peripheral circulatory complications
0.000 0.038 0.962
I25.5 Ischaemic cardiomyopathy
0.000 0.038 0.962
H34 Retinal vascular occlusions
0.000 0.039 0.961
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.043 0.957
K51 Ulcerative colitis
0.956 0.044 0.000
K51.9 Ulcerative colitis, unspecified
0.954 0.046 0.000
E07 Other disorders of thyroid
0.000 0.049 0.951
H43.3 Other vitreous opacities
0.000 0.051 0.949
K51.3 Ulcerative (chronic) rectosigmoiditis
0.949 0.051 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.056 0.944
E11.3 With ophthalmic complications
0.000 0.057 0.943
J45 Asthma
0.000 0.059 0.941
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.059 0.941
E83 Disorders of mineral metabolism
0.923 0.060 0.017
I25.2 Old myocardial infarction
0.000 0.064 0.936
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.065 0.935
K72 Hepatic failure, not elsewhere classified
0.000 0.065 0.935
M07 Psoriatic and enteropathic arthropathies
0.000 0.067 0.933
J40-J47 Chronic lower respiratory diseases
0.000 0.073 0.927
H43.8 Other disorders of vitreous body
0.000 0.075 0.925
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.076 0.924
K81.1 Chronic cholecystitis
0.000 0.077 0.923
E07.9 Disorder of thyroid, unspecified
0.000 0.078 0.922
Chapter X Diseases of the respiratory system
0.000 0.079 0.921
K81.9 Cholecystitis, unspecified
0.000 0.081 0.919
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.085 0.915
E11.2 With renal complications
0.000 0.085 0.915
K50-K52 Noninfective enteritis and colitis
0.018 0.085 0.897
I21 Acute myocardial infarction
0.000 0.086 0.914
K82.1 Hydrops of gallbladder
0.000 0.091 0.909
E11.1 With ketoacidosis
0.000 0.099 0.901
I46 Cardiac arrest
0.000 0.102 0.898
H34.2 Other retinal artery occlusions
0.000 0.110 0.890
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.111 0.889
G37.8 Other specified demyelinating diseases of central nervous system
0.888 0.112 0.000
E10.2 With renal complications
0.000 0.114 0.886
M07.3 Other psoriatic arthropathies
0.000 0.114 0.886
I47.2 Ventricular tachycardia
0.000 0.119 0.881
K74.6 Other and unspecified cirrhosis of liver
0.000 0.121 0.879
E83.3 Disorders of phosphorus metabolism
0.867 0.129 0.004
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.132 0.868
I20.1 Angina pectoris with documented spasm
0.000 0.135 0.865
K72.9 Hepatic failure, unspecified
0.000 0.137 0.863
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.138 0.862
E11.5 With peripheral circulatory complications
0.000 0.139 0.861
K51.8 Other ulcerative colitis
0.860 0.139 0.000
I15 Secondary hypertension
0.000 0.140 0.860
K75 Other inflammatory liver diseases
0.000 0.142 0.858
I21.9 Acute myocardial infarction, unspecified
0.000 0.147 0.853
I46.9 Cardiac arrest, unspecified
0.000 0.147 0.853
K73 Chronic hepatitis, not elsewhere classified
0.000 0.148 0.852
E03.8 Other specified hypothyroidism
0.000 0.152 0.848
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.153 0.847
E78.2 Mixed hyperlipidaemia
0.000 0.154 0.846
E11.0 With coma
0.000 0.162 0.838
J46 Status asthmaticus
0.000 0.163 0.837
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.166 0.834
E13 Other specified diabetes mellitus
0.000 0.166 0.834
H34.8 Other retinal vascular occlusions
0.000 0.166 0.834
K51.2 Ulcerative (chronic) proctitis
0.832 0.168 0.000
I12 Hypertensive renal disease
0.000 0.169 0.831
M06.4 Inflammatory polyarthropathy
0.000 0.172 0.828
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.827 0.173 0.000
M06.3 Rheumatoid nodule
0.000 0.175 0.825
K50 Crohn's disease [regional enteritis]
0.001 0.175 0.824
I31 Other diseases of pericardium
0.000 0.177 0.823
K55-K64 Other diseases of intestines
0.000 0.178 0.822
J86 Pyothorax
0.000 0.180 0.820
I47.0 Reentry ventricular arrhythmia
0.000 0.181 0.819
H40.1 Primary open-angle glaucoma
0.000 0.187 0.813
M65-M68 Disorders of synovium and tendon
0.000 0.188 0.812
K60 Fissure and fistula of anal and rectal regions
0.000 0.189 0.811
E16.1 Other hypoglycaemia
0.000 0.189 0.810
E11.6 With other specified complications
0.000 0.190 0.810
K74.5 Biliary cirrhosis, unspecified
0.000 0.192 0.808
M06.0 Seronegative rheumatoid arthritis
0.000 0.192 0.808
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.193 0.807
E83.5 Disorders of calcium metabolism
0.803 0.196 0.001
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.198 0.802
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.200 0.800
L43.8 Other lichen planus
0.000 0.200 0.800
I21.4 Acute subendocardial myocardial infarction
0.000 0.202 0.798
K60.2 Anal fissure, unspecified
0.000 0.203 0.797
I45 Other conduction disorders
0.000 0.203 0.797
M14 Arthropathies in other diseases classified elsewhere
0.000 0.208 0.792
E40-E46 Malnutrition
0.000 0.210 0.790
K51.5 Mucosal proctocolitis
0.789 0.210 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.211 0.789
E06 Thyroiditis
0.000 0.211 0.789
L40.8 Other psoriasis
0.000 0.212 0.788
J95-J99 Other diseases of the respiratory system
0.000 0.213 0.787
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.214 0.785
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.216 0.784
K80.8 Other cholelithiasis
0.000 0.216 0.784
I25.3 Aneurysm of heart
0.000 0.217 0.783
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.220 0.780
I51 Complications and ill-defined descriptions of heart disease
0.000 0.220 0.780
K72.0 Acute and subacute hepatic failure
0.000 0.222 0.778
I35.8 Other aortic valve disorders
0.000 0.226 0.774
E83.9 Disorder of mineral metabolism, unspecified
0.760 0.231 0.010
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.231 0.769
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.232 0.768
L40.0 Psoriasis vulgaris
0.000 0.232 0.768
M65 Synovitis and tenosynovitis
0.000 0.237 0.763
I51.8 Other ill-defined heart diseases
0.000 0.239 0.761
I25.4 Coronary artery aneurysm
0.000 0.240 0.760
E74 Other disorders of carbohydrate metabolism
0.000 0.241 0.759
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.241 0.759
J43 Emphysema
0.000 0.242 0.758
H30 Chorioretinal inflammation
0.000 0.243 0.757
E88 Other metabolic disorders
0.000 0.246 0.754
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.247 0.753
K75.4 Autoimmune hepatitis
0.000 0.251 0.749
I23 Certain current complications following acute myocardial infarction
0.000 0.252 0.747
K58 Irritable bowel syndrome
0.000 0.252 0.748
K60.0 Acute anal fissure
0.000 0.253 0.747
E78.1 Pure hyperglyceridaemia
0.000 0.255 0.745
J86.9 Pyothorax without fistula
0.000 0.257 0.743
H43.2 Crystalline deposits in vitreous body
0.000 0.258 0.742
I15.1 Hypertension secondary to other renal disorders
0.000 0.259 0.741
I31.3 Pericardial effusion (noninflammatory)
0.000 0.262 0.738
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.262 0.738
K51.4 Pseudopolyposis of colon
0.735 0.265 0.000
H34.1 Central retinal artery occlusion
0.000 0.268 0.732
K82.2 Perforation of gallbladder
0.000 0.269 0.731
H43.9 Disorder of vitreous body, unspecified
0.000 0.272 0.728
I30 Acute pericarditis
0.000 0.272 0.728
E78.8 Other disorders of lipoprotein metabolism
0.000 0.275 0.725
K82.3 Fistula of gallbladder
0.000 0.276 0.724
H40.4 Glaucoma secondary to eye inflammation
0.000 0.277 0.723
K63 Other diseases of intestine
0.000 0.277 0.723
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.277 0.723
I12.9 Hypertensive renal disease without renal failure
0.000 0.278 0.722
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.279 0.721
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.281 0.719
L42 Pityriasis rosea
0.000 0.282 0.718
J86.0 Pyothorax with fistula
0.000 0.282 0.718
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.716
L41 Parapsoriasis
0.000 0.283 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
E13.9 Without complications
0.000 0.285 0.715
I52 Other heart disorders in diseases classified elsewhere
0.000 0.286 0.714
I48 Atrial fibrillation and flutter
0.000 0.286 0.714
I41 Myocarditis in diseases classified elsewhere
0.000 0.286 0.714
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.286 0.714
I32 Pericarditis in diseases classified elsewhere
0.000 0.286 0.714
Chapter VI Diseases of the nervous system
0.704 0.286 0.010
L43.3 Subacute (active) lichen planus
0.000 0.286 0.713
L43.2 Lichenoid drug reaction
0.000 0.286 0.713
L43.1 Bullous lichen planus
0.000 0.286 0.713
L43.0 Hypertrophic lichen planus
0.000 0.286 0.713
K77 Liver disorders in diseases classified elsewhere
0.000 0.287 0.713
K71 Toxic liver disease
0.000 0.287 0.713
K51.0 Ulcerative (chronic) enterocolitis
0.712 0.288 0.000
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.289 0.711
M11 Other crystal arthropathies
0.000 0.289 0.710
E77 Disorders of glycoprotein metabolism
0.000 0.289 0.710
E76 Disorders of glycosaminoglycan metabolism
0.000 0.289 0.710
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.289 0.710
E72 Other disorders of amino-acid metabolism
0.000 0.289 0.710
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.289 0.710
E70 Disorders of aromatic amino-acid metabolism
0.000 0.289 0.710
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.289 0.710
M06.34 Rheumatoid nodule (Hand)
0.000 0.290 0.710
J98 Other respiratory disorders
0.000 0.290 0.710
E78.4 Other hyperlipidaemia
0.000 0.292 0.708
M05.8 Other seropositive rheumatoid arthritis
0.000 0.292 0.708
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.292 0.708
M05.2 Rheumatoid vasculitis
0.000 0.292 0.708
M05.1 Rheumatoid lung disease
0.000 0.292 0.708
M05.0 Felty's syndrome
0.000 0.292 0.708
H43.1 Vitreous haemorrhage
0.000 0.293 0.707
H42 Glaucoma in diseases classified elsewhere
0.000 0.293 0.707
K52 Other non-infective gastro-enteritis and colitis
0.002 0.293 0.704
K74.4 Secondary biliary cirrhosis
0.000 0.293 0.707
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.293 0.707
K74.1 Hepatic sclerosis
0.000 0.293 0.707
K80.3 Calculus of bile duct with cholangitis
0.000 0.294 0.705
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.295 0.705
K90.9 Intestinal malabsorption, unspecified
0.000 0.296 0.704
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.297 0.703
I45.2 Bifascicular block
0.000 0.297 0.703
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.298 0.702
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.298 0.702
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.298 0.702
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.298 0.702
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.298 0.702
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.298 0.702
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.298 0.702
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.298 0.702
H43.0 Vitreous prolapse
0.000 0.299 0.701
H40.6 Glaucoma secondary to drugs
0.000 0.299 0.700
H40.3 Glaucoma secondary to eye trauma
0.000 0.299 0.700
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.300 0.700
K50.8 Other Crohn's disease
0.000 0.304 0.696
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.307 0.693
K60.5 Anorectal fistula
0.000 0.308 0.692
K73.9 Chronic hepatitis, unspecified
0.000 0.310 0.690
H34.9 Retinal vascular occlusion, unspecified
0.000 0.311 0.689
H34.0 Transient retinal artery occlusion
0.000 0.311 0.689
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.312 0.688
K51.1 Ulcerative (chronic) ileocolitis
0.685 0.315 0.000
K55 Vascular disorders of intestine
0.000 0.315 0.685
I11 Hypertensive heart disease
0.000 0.316 0.684
K50.0 Crohn's disease of small intestine
0.000 0.317 0.683
E07.1 Dyshormogenetic goitre
0.000 0.318 0.682
E07.0 Hypersecretion of calcitonin
0.000 0.318 0.682
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.320 0.680
E05.9 Thyrotoxicosis, unspecified
0.000 0.320 0.680
E11.8 With unspecified complications
0.000 0.321 0.679
M45-M49 Spondylopathies
0.000 0.322 0.678
J98.4 Other disorders of lung
0.000 0.322 0.678
K50.9 Crohn's disease, unspecified
0.000 0.322 0.678
E79 Disorders of purine and pyrimidine metabolism
0.000 0.324 0.676
I40 Acute myocarditis
0.000 0.325 0.675
J45.8 Mixed asthma
0.000 0.325 0.675
J45.1 Nonallergic asthma
0.000 0.325 0.675
K90.8 Other intestinal malabsorption
0.000 0.326 0.674
K82.9 Disease of gallbladder, unspecified
0.000 0.326 0.674
I44 Atrioventricular and left bundle-branch block
0.000 0.326 0.674
E83.8 Other disorders of mineral metabolism
0.662 0.326 0.012
E83.2 Disorders of zinc metabolism
0.662 0.326 0.012
E83.0 Disorders of copper metabolism
0.662 0.326 0.012
K82.0 Obstruction of gallbladder
0.000 0.327 0.673
H40.5 Glaucoma secondary to other eye disorders
0.000 0.327 0.673
K72.1 Chronic hepatic failure
0.000 0.330 0.670
J85 Abscess of lung and mediastinum
0.000 0.330 0.670
M07.6 Other enteropathic arthropathies
0.000 0.331 0.669
M07.5 Arthropathy in ulcerative colitis
0.000 0.331 0.669
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.331 0.669
M07.2 Psoriatic spondylitis
0.000 0.331 0.669
M07.1 Arthritis mutilans
0.000 0.331 0.669
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.331 0.669
G80-G83 Cerebral palsy and other paralytic syndromes
0.666 0.332 0.002
I45.8 Other specified conduction disorders
0.000 0.334 0.666
J41 Simple and mucopurulent chronic bronchitis
0.000 0.335 0.665
M45 Ankylosing spondylitis
0.000 0.335 0.665
E06.3 Autoimmune thyroiditis
0.000 0.335 0.664
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.337 0.663
E84 Cystic fibrosis
0.000 0.338 0.661
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.339 0.661
M12 Other specific arthropathies
0.000 0.341 0.658
I15.9 Seconday hypertension, unspecified
0.000 0.342 0.657
K63.9 Disease of intestine, unspecified
0.000 0.343 0.657
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.344 0.655
E11.4 With neurological complications
0.000 0.347 0.653
I45.1 Other and unspecified right bundle-branch block
0.000 0.347 0.653
K75.8 Other specified inflammatory liver diseases
0.000 0.348 0.652
J43.2 Centrilobular emphysema
0.000 0.348 0.652
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.349 0.651
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.351 0.649
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.351 0.649
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.352 0.648
M14.6 Neuropathic arthropathy
0.000 0.356 0.644
I46.1 Sudden cardiac death, so described
0.000 0.356 0.644
I36 Nonrheumatic tricuspid valve disorders
0.000 0.356 0.644
E46 Unspecified protein-energy malnutrition
0.000 0.361 0.639
G20-G26 Extrapyramidal and movement disorders
0.637 0.361 0.002
I24.1 Dressler's syndrome
0.000 0.361 0.639
K75.0 Abscess of liver
0.000 0.364 0.636
M07.38 Other psoriatic arthropathies (Other)
0.000 0.365 0.635
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.365 0.635
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.365 0.635
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.365 0.635
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.365 0.635
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.365 0.635
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.367 0.633
G30-G32 Other degenerative diseases of the nervous system
0.627 0.369 0.004
I22.8 Subsequent myocardial infarction of other sites
0.000 0.369 0.631
I45.5 Other specified heart block
0.000 0.373 0.627
E07.8 Other specified disorders of thyroid
0.000 0.373 0.627
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.374 0.626
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.374 0.626
K63.3 Ulcer of intestine
0.000 0.375 0.625
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.376 0.624
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.378 0.621
I37 Pulmonary valve disorders
0.000 0.381 0.619
I15.8 Other secondary hypertension
0.000 0.383 0.617
I15.2 Hypertension secondary to endocrine disorders
0.000 0.383 0.617
I15.0 Renovascular hypertension
0.000 0.383 0.617
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.385 0.615
K75.2 Nonspecific reactive hepatitis
0.000 0.385 0.615
K75.1 Phlebitis of portal vein
0.000 0.385 0.615
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.385 0.615
K52.1 Toxic gastro-enteritis and colitis
0.001 0.386 0.613
K55.2 Angiodysplasia of colon
0.000 0.386 0.614
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.389 0.611
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.389 0.611
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.389 0.611
K81.8 Other cholecystitis
0.000 0.390 0.609
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.393 0.607
G20 Parkinson's disease
0.607 0.393 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.394 0.605
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.397 0.603
G81 Hemiplegia
0.601 0.398 0.001
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.399 0.601
E73 Lactose intolerance
0.000 0.399 0.601
M70-M79 Other soft tissue disorders
0.000 0.399 0.601
I51.0 Cardiac septal defect, acquired
0.000 0.400 0.600
M00-M03 Infectious arthropathies
0.000 0.401 0.599
E13.8 With unspecified complications
0.000 0.402 0.598
E13.7 With multiple complications
0.000 0.402 0.598
E13.6 With other specified complications
0.000 0.402 0.598
E13.5 With peripheral circulatory complications
0.000 0.402 0.598
E13.4 With neurological complications
0.000 0.402 0.598
E13.3 With ophthalmic complications
0.000 0.402 0.598
E13.2 With renal complications
0.000 0.402 0.598
E13.1 With ketoacidosis
0.000 0.402 0.598
E13.0 With coma
0.000 0.402 0.598
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.406 0.594
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.406 0.594
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.406 0.594
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.406 0.594
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.406 0.594
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.406 0.594
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.406 0.594
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.406 0.594
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.406 0.594
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.407 0.593
G83 Other paralytic syndromes
0.592 0.407 0.001
H31 Other disorders of choroid
0.000 0.408 0.592
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.408 0.592
M06.38 Rheumatoid nodule (Other)
0.000 0.408 0.592
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.408 0.592
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.408 0.592
M06.33 Rheumatoid nodule (Forearm)
0.000 0.408 0.592
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.408 0.592
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.408 0.592
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.408 0.592
I44.3 Other and unspecified atrioventricular block
0.000 0.409 0.591
I31.8 Other specified diseases of pericardium
0.000 0.410 0.590
I31.2 Haemopericardium, not elsewhere classified
0.000 0.410 0.590
I31.0 Chronic adhesive pericarditis
0.000 0.410 0.590
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.411 0.589
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.411 0.589
I31.9 Disease of pericardium, unspecified
0.000 0.413 0.587
I51.6 Cardiovascular disease, unspecified
0.000 0.415 0.585
G30 Alzheimer's disease
0.583 0.415 0.002
E88.2 Lipomatosis, not elsewhere classified
0.000 0.416 0.583
H30.9 Chorioretinal inflammation, unspecified
0.000 0.416 0.583
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.417 0.582
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.418 0.582
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.421 0.579
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.421 0.579
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.421 0.579
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.421 0.579
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.421 0.579
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.421 0.579
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.421 0.579
I44.7 Left bundle-branch block, unspecified
0.000 0.423 0.577
K75.9 Inflammatory liver disease, unspecified
0.000 0.424 0.576
K74.0 Hepatic fibrosis
0.000 0.427 0.573
K63.4 Enteroptosis
0.000 0.427 0.573
J42 Unspecified chronic bronchitis
0.000 0.427 0.573
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.427 0.573
K50.1 Crohn's disease of large intestine
0.000 0.427 0.572
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.428 0.572
I45.0 Right fascicular block
0.000 0.429 0.571
I12.0 Hypertensive renal disease with renal failure
0.000 0.429 0.571
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.430 0.570
M10 Gout
0.000 0.431 0.569
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.432 0.568

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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