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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130375
log Bayes Factor = 279.099
Chromosome 6   position 30,321,732  (GRCh37) Explore rs3130375 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
I73 Other peripheral vascular diseases
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
I73.9 Peripheral vascular disease, unspecified
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
I77 Other disorders of arteries and arterioles
0.999 0.001 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
N40 Hyperplasia of prostate
0.000 0.001 0.999
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
E27.1 Primary adrenocortical insufficiency
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
E27 Other disorders of adrenal gland
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
H36 Retinal disorders in diseases classified elsewhere
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.998 0.002 0.000
I77.1 Stricture of artery
0.998 0.002 0.000
J45.9 Asthma, unspecified
0.998 0.002 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.998 0.002 0.000
D80-D89 Certain disorders involving the immune mechanism
0.998 0.002 0.000
H36.0 Diabetic retinopathy
0.998 0.002 0.000
K75.4 Autoimmune hepatitis
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.997 0.003 0.000
J45 Asthma
0.997 0.003 0.000
I74 Arterial embolism and thrombosis
0.996 0.004 0.000
H34 Retinal vascular occlusions
0.996 0.004 0.000
J44 Other chronic obstructive pulmonary disease
0.996 0.004 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.994 0.006 0.000
L50-L54 Urticaria and erythema
0.994 0.006 0.000
E14.3 With ophthalmic complications
0.993 0.007 0.000
E10.1 With ketoacidosis
0.993 0.007 0.000
D86 Sarcoidosis
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.992 0.008 0.000
H34.8 Other retinal vascular occlusions
0.992 0.008 0.000
E11 Non-insulin-dependent diabetes mellitus
0.992 0.008 0.000
H43-H45 Disorders of vitreous body and globe
0.992 0.008 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.992 0.008 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.991 0.009 0.000
E83.1 Disorders of iron metabolism
0.000 0.009 0.991
N40-N51 Diseases of male genital organs
0.000 0.010 0.990
E10.2 With renal complications
0.988 0.012 0.000
C34 Malignant neoplasm of bronchus and lung
0.987 0.013 0.000
B35-B49 Mycoses
0.987 0.013 0.000
N42 Other disorders of prostate
0.000 0.013 0.987
D86.9 Sarcoidosis, unspecified
0.986 0.014 0.000
E50-E64 Other nutritional deficiencies
0.986 0.014 0.000
B37 Candidiasis
0.980 0.020 0.000
H43 Disorders of vitreous body
0.979 0.021 0.000
D50-D53 Nutritional anaemias
0.978 0.022 0.000
C34.3 Lower lobe, bronchus or lung
0.976 0.024 0.000
H43.1 Vitreous haemorrhage
0.972 0.028 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.971 0.029 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.971 0.029 0.000
M15-M19 Arthrosis
0.970 0.030 0.000
G56 Mononeuropathies of upper limb
0.969 0.031 0.000
E11.9 Without complications
0.968 0.032 0.000
G56.0 Carpal tunnel syndrome
0.967 0.033 0.000
G30-G32 Other degenerative diseases of the nervous system
0.966 0.034 0.000
I60-I69 Cerebrovascular diseases
0.964 0.036 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.963 0.037 0.000
L20-L30 Dermatitis and eczema
0.962 0.038 0.000
M17 Gonarthrosis [arthrosis of knee]
0.962 0.038 0.000
M05-M14 Inflammatory polyarthropathies
0.962 0.038 0.000
D61 Other aplastic anaemias
0.958 0.042 0.000
D50 Iron deficiency anaemia
0.955 0.045 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.955 0.045 0.000
I63 Cerebral infarction
0.954 0.046 0.000
K72 Hepatic failure, not elsewhere classified
0.952 0.048 0.000
G51 Facial nerve disorders
0.952 0.048 0.000
M17.1 Other primary gonarthrosis
0.951 0.049 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.950 0.050 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.050 0.950
K75.8 Other specified inflammatory liver diseases
0.948 0.052 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.948 0.052 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.944 0.056 0.000
Chapter XIV Diseases of the genitourinary system
0.943 0.057 0.000
N00-N08 Glomerular diseases
0.943 0.057 0.000
N42.8 Other specified disorders of prostate
0.000 0.059 0.941
E70-E90 Metabolic disorders
0.941 0.059 0.000
K90.9 Intestinal malabsorption, unspecified
0.940 0.060 0.000
H25-H28 Disorders of lens
0.940 0.060 0.000
E53 Deficiency of other B group vitamins
0.937 0.063 0.000
D50.9 Iron deficiency anaemia, unspecified
0.937 0.063 0.000
C85.1 B-cell lymphoma, unspecified
0.935 0.065 0.000
E10.4 With neurological complications
0.935 0.065 0.000
L52 Erythema nodosum
0.935 0.065 0.000
N41 Inflammatory diseases of prostate
0.000 0.066 0.934
K73 Chronic hepatitis, not elsewhere classified
0.933 0.067 0.000
B37.9 Candidiasis, unspecified
0.931 0.069 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.931 0.069 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.930 0.070 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.930 0.070 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.930 0.070 0.000
C91 Lymphoid leukaemia
0.929 0.071 0.000
E11.5 With peripheral circulatory complications
0.928 0.072 0.000
L50 Urticaria
0.928 0.072 0.000
B37.8 Candidiasis of other sites
0.927 0.073 0.000
L10-L14 Bullous disorders
0.927 0.073 0.000
B44 Aspergillosis
0.926 0.074 0.000
C15-C26 Malignant neoplasms of digestive organs
0.925 0.075 0.000
C83.3 Large cell (diffuse)
0.922 0.078 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.922 0.078 0.000
L30 Other dermatitis
0.919 0.081 0.000
H26 Other cataract
0.917 0.083 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.917 0.083 0.000
N17-N19 Renal failure
0.916 0.084 0.000
D61.9 Aplastic anaemia, unspecified
0.916 0.084 0.000
Chapter XX External causes of morbidity and mortality
0.915 0.085 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.914 0.086 0.000
N04 Nephrotic syndrome
0.913 0.087 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.913 0.087 0.000
N05 Unspecified nephritic syndrome
0.912 0.088 0.000
G51.0 Bell's palsy
0.908 0.092 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.907 0.093 0.000
I77.6 Arteritis, unspecified
0.907 0.093 0.000
E55 Vitamin D deficiency
0.906 0.094 0.000
E06 Thyroiditis
0.905 0.095 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.904 0.096 0.000
L53 Other erythematous conditions
0.904 0.096 0.000
N18 Chronic renal failure
0.903 0.097 0.000
C04 Malignant neoplasm of floor of mouth
0.901 0.099 0.000
E53.8 Deficiency of other specified B group vitamins
0.901 0.099 0.000
C25 Malignant neoplasm of pancreas
0.899 0.101 0.000
L94 Other localised connective tissue disorders
0.897 0.102 0.000
G35 Multiple sclerosis
0.897 0.103 0.000
H26.9 Cataract, unspecified
0.897 0.103 0.000
I62 Other nontraumatic intracranial haemorrhage
0.895 0.105 0.000
B02 Zoster [herpes zoster]
0.895 0.105 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.892 0.108 0.000
E89.0 Postprocedural hypothyroidism
0.892 0.108 0.000
L30.9 Dermatitis, unspecified
0.891 0.109 0.000
K50-K52 Noninfective enteritis and colitis
0.849 0.111 0.040
W00-W19 Falls
0.889 0.111 0.000
H02 Other disorders of eyelid
0.888 0.112 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.885 0.115 0.000
B37.0 Candidal stomatitis
0.884 0.116 0.000
M35.3 Polymyalgia rheumatica
0.880 0.120 0.000
N41.1 Chronic prostatitis
0.000 0.120 0.880
J46 Status asthmaticus
0.880 0.120 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.879 0.121 0.000
G31.8 Other specified degenerative diseases of nervous system
0.879 0.121 0.000
N04.9 Unspecified
0.879 0.121 0.000
M06 Other rheumatoid arthritis
0.877 0.123 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.877 0.123 0.000
W19 Unspecified fall
0.876 0.124 0.000
K72.0 Acute and subacute hepatic failure
0.873 0.127 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.873 0.127 0.000
H44 Disorders of globe
0.872 0.128 0.000
C25.9 Pancreas, unspecified
0.871 0.129 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.869 0.131 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.867 0.133 0.000
L13 Other bullous disorders
0.867 0.133 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.866 0.134 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.865 0.135 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.863 0.137 0.000
J95-J99 Other diseases of the respiratory system
0.863 0.137 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.862 0.138 0.000
L93 Lupus erythematosus
0.862 0.138 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.861 0.139 0.000
M86-M90 Other osteopathies
0.860 0.140 0.000
W19.9 Unspecified place
0.860 0.140 0.000
E03.8 Other specified hypothyroidism
0.859 0.141 0.000
M07 Psoriatic and enteropathic arthropathies
0.856 0.144 0.000
M18 Arthrosis of first carpometacarpal joint
0.856 0.144 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.855 0.144 0.000
H02.0 Entropion and trichiasis of eyelid
0.853 0.147 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.852 0.148 0.000
K52 Other non-infective gastro-enteritis and colitis
0.843 0.149 0.008
G50 Disorders of trigeminal nerve
0.851 0.149 0.000
G51.9 Disorder of facial nerve, unspecified
0.850 0.150 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.850 0.150 0.000
C81 Hodgkin's disease
0.850 0.150 0.000
M24 Other specific joint derangements
0.849 0.151 0.000
H02.5 Other disorders affecting eyelid function
0.849 0.151 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.848 0.152 0.000
E55.9 Vitamin D deficiency, unspecified
0.848 0.152 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.847 0.153 0.000
M33 Dermatopolymyositis
0.847 0.153 0.000
B02.9 Zoster without complication
0.846 0.154 0.000
G58 Other mononeuropathies
0.846 0.154 0.000
E21.0 Primary hyperparathyroidism
0.845 0.155 0.000
L28 Lichen simplex chronicus and prurigo
0.844 0.156 0.000
G31.0 Circumscribed brain atrophy
0.843 0.157 0.000
C91.1 Chronic lymphocytic leukaemia
0.842 0.158 0.000
C18 Malignant neoplasm of colon
0.842 0.158 0.000
D83 Common variable immunodeficiency
0.841 0.159 0.000
H05 Disorders of orbit
0.840 0.160 0.000
X20-X29 Contact with venomous animals and plants
0.840 0.160 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.839 0.161 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.839 0.161 0.000
M10 Gout
0.838 0.162 0.000
N18.0 End-stage renal disease
0.838 0.162 0.000
L50.9 Urticaria, unspecified
0.837 0.163 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.836 0.164 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.835 0.165 0.000
K72.9 Hepatic failure, unspecified
0.835 0.165 0.000
E78.2 Mixed hyperlipidaemia
0.834 0.166 0.000
B25-B34 Other viral diseases
0.834 0.166 0.000
I63.8 Other cerebral infarction
0.833 0.167 0.000
M34 Systemic sclerosis
0.833 0.167 0.000
N18.3 Chronic kidney disease, stage 3
0.832 0.168 0.000
B44.9 Aspergillosis, unspecified
0.831 0.169 0.000
C34.0 Main bronchus
0.829 0.171 0.000
N10-N16 Renal tubulo-interstitial diseases
0.829 0.171 0.000
M06.9 Rheumatoid arthritis, unspecified
0.828 0.172 0.000
K75.9 Inflammatory liver disease, unspecified
0.827 0.173 0.000
M60-M63 Disorders of muscles
0.827 0.173 0.000
L89 Decubitus ulcer
0.826 0.174 0.000
K76 Other diseases of liver
0.825 0.175 0.000
L13.0 Dermatitis herpetiformis
0.824 0.176 0.000
D69 Purpura and other haemorrhagic conditions
0.824 0.176 0.000
M32 Systemic lupus erythematosus
0.824 0.176 0.000
C16 Malignant neoplasm of stomach
0.823 0.177 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.178 0.822
L40-L45 Papulosquamous disorders
0.822 0.178 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.821 0.179 0.000
D50.8 Other iron deficiency anaemias
0.820 0.180 0.000
E14.2 Withrenal complications
0.820 0.180 0.000
H34.2 Other retinal artery occlusions
0.819 0.181 0.000
E11.3 With ophthalmic complications
0.819 0.181 0.000
D86.0 Sarcoidosis of lung
0.818 0.182 0.000
V20-V29 Motorcycle rider injured in transport accident
0.818 0.182 0.000
M86 Osteomyelitis
0.816 0.184 0.000
M17.9 Gonarthrosis, unspecified
0.816 0.184 0.000
N05.2 Diffuse membranous glomerulonephritis
0.815 0.185 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.814 0.186 0.000
E11.7 With multiple complications
0.813 0.187 0.000
H43.9 Disorder of vitreous body, unspecified
0.812 0.188 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.810 0.190 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.810 0.190 0.000
C18.4 Transverse colon
0.810 0.190 0.000
M31 Other necrotising vasculopathies
0.810 0.190 0.000
I73.0 Raynaud's syndrome
0.809 0.191 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.808 0.192 0.000
I27 Other pulmonary heart diseases
0.807 0.193 0.000
B44.1 Other pulmonary aspergillosis
0.806 0.194 0.000
D80 Immunodeficiency with predominantly antibody defects
0.806 0.194 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.194 0.805
E10.8 With unspecified complications
0.804 0.196 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.804 0.196 0.000
H30 Chorioretinal inflammation
0.802 0.198 0.000
C84.5 Other and unspecified T-cell lymphomas
0.801 0.199 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.799 0.201 0.000
E14.8 With unspecified complications
0.799 0.201 0.000
N48 Other disorders of penis
0.000 0.202 0.798
G58.9 Mononeuropathy, unspecified
0.798 0.202 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.798 0.202 0.000
H35 Other retinal disorders
0.797 0.203 0.000
E31 Polyglandular dysfunction
0.797 0.203 0.000
E24 Cushing's syndrome
0.797 0.203 0.000
H43.2 Crystalline deposits in vitreous body
0.796 0.204 0.000
L50.0 Allergic urticaria
0.796 0.204 0.000
C04.9 Floor of mouth, unspecified
0.795 0.205 0.000
E14.6 With other specified complications
0.795 0.205 0.000
E13 Other specified diabetes mellitus
0.791 0.209 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.791 0.209 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.791 0.209 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.789 0.211 0.000
E10.5 With peripheral circulatory complications
0.788 0.212 0.000
C07 Malignant neoplasm of parotid gland
0.787 0.213 0.000
H26.1 Traumatic cataract
0.787 0.213 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.786 0.214 0.000
X23 Contact with hornets, wasps and bees
0.786 0.214 0.000
H27 Other disorders of lens
0.786 0.214 0.000
H46 Optic neuritis
0.785 0.215 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.785 0.215 0.000
W19.2 School, other institution and public administrative area
0.784 0.216 0.000
J43 Emphysema
0.784 0.216 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.784 0.216 0.000
K90.8 Other intestinal malabsorption
0.783 0.217 0.000
N41.0 Acute prostatitis
0.000 0.217 0.783
C88 Malignant immunoproliferative diseases
0.782 0.218 0.000
G30 Alzheimer's disease
0.782 0.218 0.000
C04.0 Anterior floor of mouth
0.782 0.218 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.781 0.219 0.000
M07.3 Other psoriatic arthropathies
0.780 0.220 0.000
C13 Malignant neoplasm of hypopharynx
0.780 0.220 0.000
E14.1 With ketoacidosis
0.780 0.220 0.000
C02.9 Tongue, unspecified
0.779 0.221 0.000
C34.1 Upper lobe, bronchus or lung
0.779 0.221 0.000
C25.3 Pancreatic duct
0.778 0.222 0.000
G70-G73 Diseases of myoneural junction and muscle
0.778 0.222 0.000
M15 Polyarthrosis
0.778 0.222 0.000
R30-R39 Symptoms and signs involving the urinary system
0.000 0.222 0.778
K73.9 Chronic hepatitis, unspecified
0.777 0.223 0.000
M70-M79 Other soft tissue disorders
0.777 0.223 0.000
Q43 Other congenital malformations of intestine
0.776 0.224 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.776 0.224 0.000
L94.2 Calcinosis cutis
0.776 0.224 0.000
E06.3 Autoimmune thyroiditis
0.775 0.225 0.000
H06.2 Dysthyroid exophthalmos
0.775 0.225 0.000
M06.4 Inflammatory polyarthropathy
0.774 0.226 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.226 0.774
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.774 0.226 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.774 0.226 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.774 0.226 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.773 0.227 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.773 0.227 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.773 0.227 0.000
Q50-Q56 Congenital malformations of genital organs
0.772 0.228 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.772 0.228 0.000
E78.6 Lipoprotein deficiency
0.772 0.228 0.000
M20.1 Hallux valgus (acquired)
0.000 0.229 0.771
E06.9 Thyroiditis, unspecified
0.770 0.230 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.769 0.231 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.231 0.769
C18.9 Colon, unspecified
0.768 0.232 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.768 0.232 0.000
E51 Thiamine deficiency
0.768 0.232 0.000
H47.2 Optic atrophy
0.768 0.232 0.000
D55-D59 Haemolytic anaemias
0.766 0.234 0.000
D69.6 Thrombocytopenia, unspecified
0.766 0.234 0.000
R39 Other symptoms and signs involving the urinary system
0.000 0.234 0.766
M72 Fibroblastic disorders
0.766 0.234 0.000
A15-A19 Tuberculosis
0.766 0.234 0.000
D61.1 Drug-induced aplastic anaemia
0.765 0.235 0.000
H47.3 Other disorders of optic disk
0.764 0.236 0.000
H26.4 After-cataract
0.763 0.237 0.000
E11.1 With ketoacidosis
0.762 0.237 0.000
E11.6 With other specified complications
0.762 0.238 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.762 0.238 0.000
I70 Atherosclerosis
0.761 0.239 0.000
L27 Dermatitis due to substances taken internally
0.761 0.239 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.760 0.240 0.000
H31 Other disorders of choroid
0.759 0.241 0.000
D00-D09 In situ neoplasms
0.758 0.242 0.000
K76.9 Liver disease, unspecified
0.758 0.242 0.000
B01 Varicella [chickenpox]
0.758 0.242 0.000
I71 Aortic aneurysm and dissection
0.758 0.242 0.000
M20 Acquired deformities of fingers and toes
0.001 0.244 0.755
N42.0 Calculus of prostate
0.000 0.244 0.755
C34.9 Bronchus or lung, unspecified
0.755 0.245 0.000
N48.1 Balanoposthitis
0.000 0.245 0.755
M86.9 Osteomyelitis, unspecified
0.754 0.246 0.000
E14.5 With peripheral circulatory complications
0.754 0.246 0.000
L23 Allergic contact dermatitis
0.753 0.246 0.000
L53.9 Erythematous condition, unspecified
0.752 0.248 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.752 0.248 0.000
L93.0 Discoid lupus erythematosus
0.752 0.248 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.751 0.249 0.000
D51 Vitamin B12 deficiency anaemia
0.751 0.249 0.000
D53 Other nutritional anaemias
0.751 0.249 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.750 0.250 0.000
E10.0 With coma
0.749 0.251 0.000
L43 Lichen planus
0.749 0.251 0.000
I27.2 Other secondary pulmonary hypertension
0.748 0.252 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.253 0.747
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.747 0.253 0.000
K76.6 Portal hypertension
0.746 0.254 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.746 0.254 0.000
L53.8 Other specified erythematous conditions
0.746 0.254 0.000
E61 Deficiency of other nutrient elements
0.746 0.254 0.000
C03 Malignant neoplasm of gum
0.745 0.255 0.000
C84.0 Mycosis fungoides
0.745 0.255 0.000
J41 Simple and mucopurulent chronic bronchitis
0.744 0.256 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.743 0.257 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.743 0.257 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.743 0.257 0.000
D84 Other immunodeficiencies
0.743 0.257 0.000
N25-N29 Other disorders of kidney and ureter
0.742 0.258 0.000
H44.0 Purulent endophthalmitis
0.742 0.258 0.000
M11 Other crystal arthropathies
0.742 0.258 0.000
B25 Cytomegaloviral disease
0.742 0.258 0.000
C91.4 Hairy-cell leukaemia
0.742 0.258 0.000
I77.2 Rupture of artery
0.739 0.261 0.000
N42.2 Atrophy of prostate
0.000 0.261 0.739
L94.0 Localised scleroderma [morphea]
0.739 0.261 0.000
C83.0 Small cell (diffuse)
0.738 0.262 0.000
M17.0 Primary gonarthrosis, bilateral
0.738 0.262 0.000
I00-I02 Acute rheumatic fever
0.738 0.262 0.000
C95 Leukaemia of unspecified cell type
0.737 0.263 0.000
H02.1 Ectropion of eyelid
0.737 0.263 0.000
M35.7 Hypermobility syndrome
0.737 0.263 0.000
I74.5 Embolism and thrombosis of iliac artery
0.736 0.264 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.736 0.264 0.000
N13 Obstructive and reflux uropathy
0.736 0.264 0.000
L95.9 Vasculitis limited to skin, unspecified
0.735 0.265 0.000
H34.9 Retinal vascular occlusion, unspecified
0.735 0.265 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.735 0.265 0.000
B37.4 Candidiasis of other urogenital sites
0.734 0.266 0.000
C93 Monocytic leukaemia
0.734 0.266 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.734 0.266 0.000
N05.1 Focal and segmental glomerular lesions
0.734 0.266 0.000
H35.8 Other specified retinal disorders
0.734 0.266 0.000
M65-M68 Disorders of synovium and tendon
0.734 0.266 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.733 0.267 0.000
E23 Hypofunction and other disorders of pituitary gland
0.733 0.267 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.733 0.267 0.000
I74.8 Embolism and thrombosis of other arteries
0.731 0.269 0.000
D04 Carcinoma in situ of skin
0.731 0.269 0.000
E14.9 Without complications
0.731 0.269 0.000
L53.0 Toxic erythema
0.731 0.269 0.000
C38.4 Pleura
0.730 0.270 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.730 0.270 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.730 0.270 0.000
D83.9 Common variable immunodeficiency, unspecified
0.728 0.272 0.000
L12 Pemphigoid
0.728 0.272 0.000
C34.2 Middle lobe, bronchus or lung
0.727 0.273 0.000
L89.2 Stage III decubitus ulcer
0.727 0.273 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.726 0.274 0.000
H02.6 Xanthelasma of eyelid
0.726 0.274 0.000
M12 Other specific arthropathies
0.726 0.274 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.725 0.275 0.000
C91.9 Lymphoid leukaemia, unspecified
0.725 0.275 0.000
M00-M03 Infectious arthropathies
0.725 0.275 0.000
D86.1 Sarcoidosis of lymph nodes
0.725 0.275 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.725 0.275 0.000
L28.0 Lichen simplex chronicus
0.724 0.276 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.724 0.276 0.000
N18.4 Chronic kidney disease, stage 4
0.724 0.276 0.000
V01-V09 Pedestrian injured in transport accident
0.724 0.276 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.723 0.277 0.000
N11 Chronic tubulo-interstitial nephritis
0.723 0.277 0.000
E89.2 Postprocedural hypoparathyroidism
0.723 0.277 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.722 0.277 0.000
E16.1 Other hypoglycaemia
0.722 0.278 0.000
A80-A89 Viral infections of the central nervous system
0.722 0.278 0.000
X23.9 Unspecified place
0.721 0.279 0.000
H02.3 Blepharochalasis
0.721 0.279 0.000
E11.8 With unspecified complications
0.720 0.280 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.720 0.280 0.000
E20 Hypoparathyroidism
0.719 0.281 0.000
M10.9 Gout, unspecified
0.719 0.281 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.718 0.282 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
K71 Toxic liver disease
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
R30 Pain associated with micturition
0.000 0.283 0.717
K75.3 Granulomatous hepatitis, not elsewhere classified
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.717 0.283 0.000
K75.1 Phlebitis of portal vein
0.717 0.283 0.000
I77.5 Necrosis of artery
0.717 0.283 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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