TreeWAS – Variant ID: rs3130564

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
K70-K77 Diseases of liver	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
D64 Other anaemias	1.000	0.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000	0.000
K75 Other inflammatory liver diseases	1.000	0.000	0.000
I73 Other peripheral vascular diseases	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
C15-C26 Malignant neoplasms of digestive organs	1.000	0.000	0.000
K90 Intestinal malabsorption	1.000	0.000	0.000
K75.4 Autoimmune hepatitis	0.999	0.001	0.000
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
H36.0 Diabetic retinopathy	0.999	0.001	0.000
H30-H36 Disorders of choroid and retina	0.998	0.002	0.000
H36 Retinal disorders in diseases classified elsewhere	0.998	0.002	0.000
L40 Psoriasis	0.000	0.002	0.998
Chapter XI Diseases of the digestive system	0.998	0.002	0.000
E10.1 With ketoacidosis	0.998	0.002	0.000
J45.9 Asthma, unspecified	0.998	0.002	0.000
I73.0 Raynaud's syndrome	0.997	0.003	0.000
Chapter IX Diseases of the circulatory system	0.997	0.003	0.000
C18 Malignant neoplasm of colon	0.997	0.003	0.000
E14.3 With ophthalmic complications	0.997	0.003	0.000
K90-K93 Other diseases of the digestive system	0.997	0.003	0.000
E27.1 Primary adrenocortical insufficiency	0.997	0.003	0.000
Chapter VII Diseases of the eye and adnexa	0.997	0.003	0.000
E27 Other disorders of adrenal gland	0.997	0.003	0.000
I74 Arterial embolism and thrombosis	0.994	0.006	0.000
C18.7 Sigmoid colon	0.994	0.006	0.000
K73 Chronic hepatitis, not elsewhere classified	0.993	0.007	0.000
M35.0 Sicca syndrome [Sjogren]	0.993	0.007	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.993	0.007	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.991	0.009	0.000
I73.9 Peripheral vascular disease, unspecified	0.991	0.009	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.990	0.010	0.000
M06.9 Rheumatoid arthritis, unspecified	0.989	0.011	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.987	0.013	0.000
D80-D89 Certain disorders involving the immune mechanism	0.986	0.014	0.000
E16 Other disorders of pancreatic internal secretion	0.985	0.015	0.000
M35 Other systemic involvement of connective tissue	0.985	0.015	0.000
L40.5 Arthropathic psoriasis	0.000	0.015	0.985
C83.3 Large cell (diffuse)	0.983	0.017	0.000
H33 Retinal detachments and breaks	0.983	0.017	0.000
Chapter I Certain infectious and parasitic diseases	0.982	0.018	0.000
C16 Malignant neoplasm of stomach	0.982	0.018	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.982	0.018	0.000
E16.2 Hypoglycaemia, unspecified	0.980	0.020	0.000
M06 Other rheumatoid arthritis	0.980	0.020	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.977	0.023	0.000
M05-M14 Inflammatory polyarthropathies	0.977	0.023	0.000
C91 Lymphoid leukaemia	0.973	0.027	0.000
B35-B49 Mycoses	0.972	0.028	0.000
M20-M25 Other joint disorders	0.972	0.028	0.000
K75.8 Other specified inflammatory liver diseases	0.966	0.034	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.964	0.036	0.000
H33.3 Retinal breaks without detachment	0.962	0.038	0.000
H33.1 Retinoschisis and retinal cysts	0.961	0.039	0.000
D69 Purpura and other haemorrhagic conditions	0.961	0.039	0.000
C85.1 B-cell lymphoma, unspecified	0.960	0.040	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.960	0.040	0.000
K72 Hepatic failure, not elsewhere classified	0.959	0.041	0.000
L40.0 Psoriasis vulgaris	0.000	0.041	0.959
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.957	0.043	0.000
E10.2 With renal complications	0.956	0.044	0.000
I77 Other disorders of arteries and arterioles	0.955	0.045	0.000
K73.9 Chronic hepatitis, unspecified	0.953	0.047	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.953	0.047	0.000
K70 Alcoholic liver disease	0.953	0.047	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.952	0.048	0.000
C91.1 Chronic lymphocytic leukaemia	0.950	0.050	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.948	0.052	0.000
I74.5 Embolism and thrombosis of iliac artery	0.947	0.053	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.944	0.056	0.000
B37 Candidiasis	0.940	0.060	0.000
D69.6 Thrombocytopenia, unspecified	0.939	0.061	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.938	0.062	0.000
K90.9 Intestinal malabsorption, unspecified	0.937	0.063	0.000
K74 Fibrosis and cirrhosis of liver	0.937	0.063	0.000
D80 Immunodeficiency with predominantly antibody defects	0.936	0.064	0.000
I74.8 Embolism and thrombosis of other arteries	0.934	0.066	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.933	0.067	0.000
E10.4 With neurological complications	0.930	0.070	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.923	0.070	0.007
I05-I09 Chronic rheumatic heart diseases	0.928	0.072	0.000
H06.2 Dysthyroid exophthalmos	0.927	0.073	0.000
B37.9 Candidiasis, unspecified	0.927	0.073	0.000
J45 Asthma	0.925	0.075	0.000
I77.1 Stricture of artery	0.923	0.077	0.000
D61 Other aplastic anaemias	0.915	0.085	0.000
D86 Sarcoidosis	0.910	0.090	0.000
Chapter X Diseases of the respiratory system	0.908	0.092	0.000
I08 Multiple valve diseases	0.906	0.094	0.000
E14.9 Without complications	0.897	0.103	0.000
M34 Systemic sclerosis	0.896	0.104	0.000
L50-L54 Urticaria and erythema	0.894	0.106	0.001
K70.9 Alcoholic liver disease, unspecified	0.894	0.106	0.000
J40-J47 Chronic lower respiratory diseases	0.894	0.106	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.893	0.107	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.890	0.110	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.890	0.110	0.000
E07 Other disorders of thyroid	0.889	0.111	0.000
D86.9 Sarcoidosis, unspecified	0.888	0.112	0.000
B35 Dermatophytosis	0.887	0.113	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.884	0.116	0.000
L20-L30 Dermatitis and eczema	0.883	0.117	0.001
E28 Ovarian dysfunction	0.881	0.119	0.000
K72.9 Hepatic failure, unspecified	0.880	0.120	0.000
C71 Malignant neoplasm of brain	0.876	0.124	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.874	0.126	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.874	0.126	0.000
C16.0 Cardia	0.873	0.127	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.873	0.127	0.000
L10-L14 Bullous disorders	0.869	0.127	0.004
C04 Malignant neoplasm of floor of mouth	0.871	0.129	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.868	0.131	0.000
C16.9 Stomach, unspecified	0.866	0.134	0.000
I77.6 Arteritis, unspecified	0.866	0.134	0.000
C07 Malignant neoplasm of parotid gland	0.866	0.134	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.862	0.138	0.000
D50-D53 Nutritional anaemias	0.861	0.139	0.000
E10.8 With unspecified complications	0.859	0.141	0.000
D61.9 Aplastic anaemia, unspecified	0.859	0.141	0.000
B25-B34 Other viral diseases	0.858	0.142	0.000
K72.0 Acute and subacute hepatic failure	0.857	0.143	0.000
B44 Aspergillosis	0.856	0.144	0.000
J95-J99 Other diseases of the respiratory system	0.854	0.146	0.000
B02 Zoster [herpes zoster]	0.853	0.147	0.000
L30 Other dermatitis	0.851	0.149	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.851	0.149	0.000
D62 Acute posthaemorrhagic anaemia	0.850	0.150	0.000
L40.8 Other psoriasis	0.000	0.152	0.848
K74.3 Primary biliary cirrhosis	0.847	0.153	0.000
E03.8 Other specified hypothyroidism	0.846	0.154	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.844	0.156	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.844	0.156	0.000
C18.5 Splenic flexure	0.842	0.158	0.000
C15 Malignant neoplasm of oesophagus	0.841	0.159	0.000
K70.0 Alcoholic fatty liver	0.840	0.160	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.838	0.162	0.000
I08.8 Other multiple valve diseases	0.836	0.164	0.000
H05 Disorders of orbit	0.836	0.164	0.000
L52 Erythema nodosum	0.835	0.165	0.000
K74.6 Other and unspecified cirrhosis of liver	0.835	0.165	0.000
J33.0 Polyp of nasal cavity	0.834	0.166	0.000
L30.9 Dermatitis, unspecified	0.834	0.166	0.000
C02.9 Tongue, unspecified	0.833	0.167	0.000
L13 Other bullous disorders	0.830	0.168	0.002
B35.1 Tinea unguium	0.832	0.168	0.000
J33 Nasal polyp	0.832	0.168	0.000
E14.6 With other specified complications	0.830	0.170	0.000
E14.1 With ketoacidosis	0.830	0.170	0.000
Chapter VIII Diseases of the ear and mastoid process	0.829	0.171	0.000
E10.0 With coma	0.829	0.171	0.000
C18.1 Appendix	0.828	0.172	0.000
D69.4 Other primary thrombocytopenia	0.828	0.172	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.826	0.174	0.000
C18.9 Colon, unspecified	0.826	0.174	0.000
C88 Malignant immunoproliferative diseases	0.826	0.174	0.000
E10.5 With peripheral circulatory complications	0.826	0.174	0.000
C81 Hodgkin's disease	0.823	0.177	0.000
E23 Hypofunction and other disorders of pituitary gland	0.822	0.178	0.000
C16.8 Overlapping lesion of stomach	0.821	0.179	0.000
C71.0 Cerebrum, except lobes and ventricles	0.820	0.180	0.000
H30 Chorioretinal inflammation	0.818	0.182	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.818	0.182	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.816	0.184	0.000
J98 Other respiratory disorders	0.812	0.188	0.000
M35.1 Other overlap syndromes	0.811	0.189	0.000
E11 Non-insulin-dependent diabetes mellitus	0.811	0.189	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.810	0.190	0.000
M32 Systemic lupus erythematosus	0.809	0.191	0.000
C16.3 Pyloric antrum	0.809	0.191	0.000
E31 Polyglandular dysfunction	0.809	0.191	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.808	0.192	0.000
M35.3 Polymyalgia rheumatica	0.807	0.193	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.807	0.193	0.000
D69.5 Secondary thrombocytopenia	0.806	0.194	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.806	0.194	0.000
B25 Cytomegaloviral disease	0.805	0.195	0.000
L13.0 Dermatitis herpetiformis	0.803	0.197	0.001
E24 Cushing's syndrome	0.802	0.198	0.000
D83 Common variable immunodeficiency	0.802	0.198	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.801	0.199	0.000
J33.9 Nasal polyp, unspecified	0.801	0.199	0.000
J30-J39 Other diseases of upper respiratory tract	0.800	0.200	0.000
E14.2 Withrenal complications	0.800	0.200	0.000
M12 Other specific arthropathies	0.799	0.201	0.000
B02.9 Zoster without complication	0.799	0.201	0.000
E14.8 With unspecified complications	0.798	0.202	0.000
C18.6 Descending colon	0.798	0.202	0.000
C10 Malignant neoplasm of oropharynx	0.794	0.206	0.000
C21 Malignant neoplasm of anus and anal canal	0.794	0.206	0.000
C02.1 Border of tongue	0.794	0.206	0.000
I71 Aortic aneurysm and dissection	0.790	0.210	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.790	0.210	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.790	0.210	0.000
H34 Retinal vascular occlusions	0.789	0.211	0.000
E11.3 With ophthalmic complications	0.788	0.212	0.000
H33.4 Traction detachment of retina	0.788	0.212	0.000
C16.6 Greater curvature of stomach, unspecified	0.785	0.215	0.000
D69.0 Allergic purpura	0.784	0.216	0.000
J98.4 Other disorders of lung	0.784	0.216	0.000
C92 Myeloid leukaemia	0.782	0.218	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.782	0.218	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.782	0.218	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.782	0.218	0.000
E10.6 With other specified complications	0.781	0.219	0.000
E40-E46 Malnutrition	0.780	0.220	0.000
C15.4 Middle third of oesophagus	0.779	0.221	0.000
E20 Hypoparathyroidism	0.779	0.221	0.000
E23.2 Diabetes insipidus	0.778	0.222	0.000
C95 Leukaemia of unspecified cell type	0.777	0.223	0.000
C23 Malignant neoplasm of gallbladder	0.776	0.224	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.775	0.225	0.000
K71 Toxic liver disease	0.775	0.225	0.000
M10 Gout	0.775	0.225	0.000
C84.5 Other and unspecified T-cell lymphomas	0.773	0.227	0.000
D50 Iron deficiency anaemia	0.772	0.228	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.771	0.229	0.000
E07.9 Disorder of thyroid, unspecified	0.770	0.230	0.000
M35.7 Hypermobility syndrome	0.769	0.231	0.000
M60-M63 Disorders of muscles	0.769	0.231	0.000
L40.1 Generalised pustular psoriasis	0.000	0.232	0.768
C70 Malignant neoplasm of meninges	0.767	0.233	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.766	0.233	0.000
M34.1 CR(E)ST syndrome	0.766	0.234	0.000
E10.7 With multiple complications	0.766	0.234	0.000
M06.3 Rheumatoid nodule	0.764	0.236	0.000
C71.9 Brain, unspecified	0.763	0.237	0.000
H80-H83 Diseases of inner ear	0.761	0.239	0.000
C03 Malignant neoplasm of gum	0.760	0.240	0.000
C05 Malignant neoplasm of palate	0.759	0.241	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.759	0.241	0.000
L28 Lichen simplex chronicus and prurigo	0.758	0.242	0.000
C91.9 Lymphoid leukaemia, unspecified	0.758	0.242	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.758	0.242	0.000
D55-D59 Haemolytic anaemias	0.757	0.243	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.756	0.244	0.000
I99 Other and unspecified disorders of circulatory system	0.755	0.245	0.000
C18.0 Caecum	0.754	0.246	0.000
E06 Thyroiditis	0.753	0.247	0.000
D84 Other immunodeficiencies	0.753	0.247	0.000
E14.5 With peripheral circulatory complications	0.753	0.247	0.000
A15-A19 Tuberculosis	0.752	0.248	0.000
D69.2 Other nonthrombocytopenic purpura	0.750	0.250	0.000
B01 Varicella [chickenpox]	0.750	0.250	0.000
H04 Disorders of lachrymal system	0.749	0.251	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.748	0.252	0.000
C83.0 Small cell (diffuse)	0.748	0.252	0.000
C06.0 Cheek mucosa	0.747	0.253	0.000
C91.5 Adult T-cell leukaemia	0.747	0.253	0.000
E28.3 Primary ovarian failure	0.747	0.253	0.000
M05 Seropositive rheumatoid arthritis	0.747	0.253	0.000
L50 Urticaria	0.744	0.255	0.000
K70.4 Alcoholic hepatic failure	0.743	0.257	0.000
E11.1 With ketoacidosis	0.741	0.259	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.741	0.259	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.741	0.259	0.000
C04.0 Anterior floor of mouth	0.740	0.260	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.740	0.260	0.000
M34.8 Other forms of systemic sclerosis	0.737	0.263	0.000
C16.2 Body of stomach	0.736	0.264	0.000
D69.8 Other specified haemorrhagic conditions	0.736	0.264	0.000
B25.9 Cytomegaloviral disease, unspecified	0.733	0.267	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.732	0.268	0.000
L51 Erythema multiforme	0.731	0.269	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.731	0.269	0.000
E27.2 Addisonian crisis	0.729	0.271	0.000
C91.4 Hairy-cell leukaemia	0.729	0.271	0.000
M86-M90 Other osteopathies	0.729	0.271	0.000
I77.2 Rupture of artery	0.728	0.272	0.000
B44.1 Other pulmonary aspergillosis	0.728	0.272	0.000
K90.8 Other intestinal malabsorption	0.724	0.275	0.000
E28.2 Polycystic ovarian syndrome	0.723	0.277	0.000
B37.2 Candidiasis of skin and nail	0.722	0.278	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.721	0.278	0.000
E07.8 Other specified disorders of thyroid	0.721	0.279	0.000
A20-A28 Certain zoonotic bacterial diseases	0.721	0.279	0.000
A63.0 Anogenital (venereal) warts	0.720	0.280	0.000
C16.4 Pylorus	0.718	0.282	0.000
C00 Malignant neoplasm of lip	0.718	0.282	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
K77 Liver disorders in diseases classified elsewhere	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.717	0.283	0.000
C94 Other leukaemias of specified cell type	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
K75.2 Nonspecific reactive hepatitis	0.717	0.283	0.000
K75.1 Phlebitis of portal vein	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.717	0.283	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.717	0.283	0.000
K90.1 Tropical sprue	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.716	0.284	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.716	0.284	0.000
L40.4 Guttate psoriasis	0.000	0.284	0.716
L40.3 Pustulosis palmaris et plantaris	0.000	0.284	0.716
L40.2 Acrodermatitis continua	0.000	0.284	0.716
E03.0 Congenital hypothyroidism with diffuse goitre	0.715	0.284	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.715	0.285	0.000
E27.5 Adrenomedullary hyperfunction	0.715	0.285	0.000
E27.0 Other adrenocortical overactivity	0.715	0.285	0.000
C71.7 Brain stem	0.714	0.286	0.000
M06.8 Other specified rheumatoid arthritis	0.714	0.286	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.714	0.286	0.000
B37.0 Candidal stomatitis	0.714	0.286	0.000
L23 Allergic contact dermatitis	0.713	0.287	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.713	0.287	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.712	0.288	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.712	0.288	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.712	0.288	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.712	0.288	0.000
C85.0 Lymphosarcoma	0.712	0.288	0.000
E15 Nondiabetic hypoglycaemic coma	0.711	0.289	0.000
C69 Malignant neoplasm of eye and adnexa	0.710	0.290	0.000
C04.9 Floor of mouth, unspecified	0.709	0.291	0.000
M34.0 Progressive systemic sclerosis	0.709	0.291	0.000
C83.6 Undifferentiated (diffuse)	0.708	0.292	0.000
C83.5 Lymphoblastic (diffuse)	0.708	0.292	0.000
C83.4 Immunoblastic (diffuse)	0.708	0.292	0.000
C83.2 Mixed small and large cell (diffuse)	0.708	0.292	0.000
D81 Combined immunodeficiencies	0.707	0.293	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.706	0.293	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.706	0.293	0.000
E16.4 Abnormal secretion of gastrin	0.706	0.293	0.000
E16.3 Increased secretion of glucagon	0.706	0.293	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.706	0.294	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.706	0.294	0.000
M35.5 Multifocal fibrosclerosis	0.706	0.294	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.706	0.294	0.000
J85 Abscess of lung and mediastinum	0.705	0.295	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.704	0.296	0.000
A75-A79 Rickettsioses	0.704	0.296	0.000
A70-A74 Other diseases caused by chlamydiae	0.704	0.296	0.000
D69.9 Haemorrhagic condition, unspecified	0.703	0.297	0.000
D64.8 Other specified anaemias	0.703	0.297	0.000
M06.2 Rheumatoid bursitis	0.702	0.297	0.000
M06.1 Adult-onset Still's disease	0.702	0.297	0.000
L40-L45 Papulosquamous disorders	0.353	0.298	0.350
C83.1 Small cleaved cell (diffuse)	0.701	0.299	0.000
H80 Otosclerosis	0.701	0.299	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.700	0.300	0.000
M08 Juvenile arthritis	0.700	0.300	0.000
H05.0 Acute inflammation of orbit	0.700	0.300	0.000
D86.3 Sarcoidosis of skin	0.700	0.300	0.000
H05.2 Exophthalmic conditions	0.700	0.300	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.700	0.300	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.697	0.303	0.000
C91.7 Other lymphoid leukaemia	0.697	0.303	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.697	0.303	0.000
C91.3 Prolymphocytic leukaemia	0.697	0.303	0.000
C91.2 Subacute lymphocytic leukaemia	0.697	0.303	0.000
B44.9 Aspergillosis, unspecified	0.697	0.303	0.000
B48 Other mycoses, not elsewhere classified	0.697	0.303	0.000
B47 Mycetoma	0.697	0.303	0.000
B46 Zygomycosis	0.697	0.303	0.000
B45 Cryptococcosis	0.697	0.303	0.000
B43 Chromomycosis and phaeomycotic abscess	0.697	0.303	0.000
B42 Sporotrichosis	0.697	0.303	0.000
B41 Paracoccidioidomycosis	0.697	0.303	0.000
B40 Blastomycosis	0.697	0.303	0.000
B39 Histoplasmosis	0.697	0.303	0.000
B38 Coccidioidomycosis	0.697	0.303	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.697	0.303	0.000
C86 Other specified types of T/NK-cell lymphoma	0.695	0.305	0.000
C13 Malignant neoplasm of hypopharynx	0.695	0.305	0.000
D00-D09 In situ neoplasms	0.695	0.305	0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.694	0.306	0.000
C92.1 Chronic myeloid leukaemia	0.692	0.308	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.692	0.308	0.000
D67 Hereditary factor IX deficiency	0.691	0.309	0.000
E22 Hyperfunction of pituitary gland	0.691	0.309	0.000
I06 Rheumatic aortic valve diseases	0.690	0.310	0.000
B35.6 Tinea cruris	0.690	0.310	0.000
D50.8 Other iron deficiency anaemias	0.690	0.310	0.000
D69.1 Qualitative platelet defects	0.689	0.311	0.000
E03.1 Congenital hypothyroidism without goitre	0.688	0.312	0.000
C02.2 Ventral surface of tongue	0.688	0.312	0.000
K72.1 Chronic hepatic failure	0.687	0.313	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.687	0.313	0.000
B91 Sequelae of poliomyelitis	0.687	0.313	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.686	0.314	0.000
M33 Dermatopolymyositis	0.685	0.315	0.000
I77.5 Necrosis of artery	0.685	0.315	0.000
I77.4 Coeliac artery compression syndrome	0.685	0.315	0.000
I77.3 Arterial fibromuscular dysplasia	0.685	0.315	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.685	0.315	0.000
J41 Simple and mucopurulent chronic bronchitis	0.685	0.315	0.000
E24.2 Drug-induced Cushing's syndrome	0.682	0.318	0.000
H55-H59 Other disorders of eye and adnexa	0.682	0.318	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.681	0.319	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.681	0.319	0.000
C71.4 Occipital lobe	0.680	0.320	0.000
D82 Immunodeficiency associated with other major defects	0.679	0.321	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.678	0.322	0.000
C81.1 Nodular sclerosis	0.678	0.322	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.677	0.322	0.000
I00-I02 Acute rheumatic fever	0.677	0.323	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.677	0.323	0.000
M10.0 Idiopathic gout	0.677	0.323	0.000
M22 Disorders of patella	0.675	0.325	0.000
A65-A69 Other spirochaetal diseases	0.674	0.326	0.000
C06.2 Retromolar area	0.674	0.326	0.000
B37.6 Candidal endocarditis	0.674	0.326	0.000
B37.5 Candidal meningitis	0.674	0.326	0.000
M06.4 Inflammatory polyarthropathy	0.673	0.327	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.672	0.328	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.672	0.328	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.672	0.328	0.000
E31.0 Autoimmune polyglandular failure	0.672	0.328	0.000
K74.4 Secondary biliary cirrhosis	0.672	0.328	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.672	0.328	0.000
K74.1 Hepatic sclerosis	0.672	0.328	0.000
C16.1 Fundus of stomach	0.671	0.329	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.671	0.329	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.671	0.329	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.671	0.329	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.671	0.329	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.671	0.329	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.671	0.329	0.000
C11 Malignant neoplasm of nasopharynx	0.671	0.329	0.000
C93 Monocytic leukaemia	0.671	0.329	0.000
L50.1 Idiopathic urticaria	0.670	0.330	0.000
D83.9 Common variable immunodeficiency, unspecified	0.670	0.330	0.000
M34.9 Systemic sclerosis, unspecified	0.669	0.331	0.000
C02.8 Overlapping lesion of tongue	0.669	0.331	0.000
C02.0 Dorsal surface of tongue	0.669	0.331	0.000
L20 Atopic dermatitis	0.668	0.332	0.000
J45.8 Mixed asthma	0.668	0.332	0.000
J37 Chronic laryngitis and laryngotracheitis	0.668	0.332	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.668	0.332	0.000
B02.2 Zoster with other nervous system involvement	0.667	0.333	0.000
C01 Malignant neoplasm of base of tongue	0.667	0.333	0.000
C83.7 Burkitt's tumour	0.667	0.333	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.666	0.333	0.000
K74.5 Biliary cirrhosis, unspecified	0.666	0.334	0.000
B33 Other viral diseases, not elsewhere classified	0.666	0.334	0.000
B02.3 Zoster ocular disease	0.665	0.335	0.000
M31 Other necrotising vasculopathies	0.665	0.335	0.000
D52 Folate deficiency anaemia	0.664	0.336	0.000
B37.1 Pulmonary candidiasis	0.664	0.336	0.000
J45.1 Nonallergic asthma	0.663	0.337	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.662	0.338	0.000
B37.7 Candidal septicaemia	0.662	0.338	0.000
H30.9 Chorioretinal inflammation, unspecified	0.662	0.338	0.000
E16.1 Other hypoglycaemia	0.661	0.338	0.000
C16.5 Lesser curvature of stomach, unspecified	0.660	0.340	0.000
L53 Other erythematous conditions	0.658	0.341	0.000
H31 Other disorders of choroid	0.658	0.342	0.000
H80.9 Otosclerosis, unspecified	0.658	0.342	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.658	0.342	0.000
J46 Status asthmaticus	0.657	0.343	0.000
D61.0 Constitutional aplastic anaemia	0.657	0.343	0.000
J98.2 Interstitial emphysema	0.656	0.343	0.000
D61.8 Other specified aplastic anaemias	0.656	0.344	0.000
D61.3 Idiopathic aplastic anaemia	0.656	0.344	0.000
D61.2 Aplastic anaemia due to other external agents	0.656	0.344	0.000
C15.9 Oesophagus, unspecified	0.656	0.344	0.000
C10.9 Oropharynx, unspecified	0.654	0.346	0.000
M35.2 Behcet's disease	0.652	0.348	0.000
H34.8 Other retinal vascular occlusions	0.652	0.348	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.652	0.348	0.000
I07 Rheumatic tricuspid valve diseases	0.652	0.348	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations