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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130743
log Bayes Factor = 54.1051
Chromosome 6   position 29,142,064  (GRCh37) Explore rs3130743 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.006 0.994
E10.2 With renal complications
0.000 0.043 0.957
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.051 0.949
E10.1 With ketoacidosis
0.000 0.101 0.899
E10.4 With neurological complications
0.000 0.126 0.874
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.188 0.812
E05.8 Other thyrotoxicosis
0.000 0.194 0.806
E16.1 Other hypoglycaemia
0.000 0.202 0.798
E13 Other specified diabetes mellitus
0.000 0.219 0.781
E10.7 With multiple complications
0.000 0.245 0.755
E14 Unspecified diabetes mellitus
0.000 0.248 0.752
E40-E46 Malnutrition
0.000 0.251 0.749
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.715
E10.0 With coma
0.000 0.314 0.686
E07 Other disorders of thyroid
0.000 0.335 0.665
E10.6 With other specified complications
0.000 0.341 0.659
E14.3 With ophthalmic complications
0.000 0.352 0.648
E10.5 With peripheral circulatory complications
0.000 0.352 0.648
E06 Thyroiditis
0.000 0.355 0.645
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.357 0.643
E13.9 Without complications
0.000 0.367 0.633
E14.1 With ketoacidosis
0.000 0.384 0.616
E03 Other hypothyroidism
0.000 0.399 0.601
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.410 0.589
E14.8 With unspecified complications
0.000 0.424 0.576
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.573 0.427 0.000
E14.4 With neurological complications
0.000 0.429 0.571
E46 Unspecified protein-energy malnutrition
0.000 0.430 0.570
E13.8 With unspecified complications
0.000 0.440 0.560
E13.7 With multiple complications
0.000 0.440 0.560
E13.6 With other specified complications
0.000 0.440 0.560
E13.5 With peripheral circulatory complications
0.000 0.440 0.560
E13.4 With neurological complications
0.000 0.440 0.560
E13.2 With renal complications
0.000 0.440 0.560
E13.1 With ketoacidosis
0.000 0.440 0.560
E13.0 With coma
0.000 0.440 0.560
E14.6 With other specified complications
0.000 0.441 0.559
E13.3 With ophthalmic complications
0.000 0.452 0.547
E14.7 With multiple complications
0.000 0.461 0.539
E06.9 Thyroiditis, unspecified
0.000 0.462 0.538
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.463 0.537
E45 Retarded development following protein-energy malnutrition
0.000 0.463 0.537
E43 Unspecified severe protein-energy malnutrition
0.000 0.463 0.537
E42 Marasmic kwashiorkor
0.000 0.463 0.537
E41 Nutritional marasmus
0.000 0.463 0.537
E40 Kwashiorkor
0.000 0.463 0.537
E10.8 With unspecified complications
0.000 0.467 0.532
E07.8 Other specified disorders of thyroid
0.000 0.472 0.528
E14.5 With peripheral circulatory complications
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E14.0 With coma
0.000 0.492 0.508
E14.2 Withrenal complications
0.000 0.500 0.500
E06.1 Subacute thyroiditis
0.000 0.511 0.489
E07.1 Dyshormogenetic goitre
0.000 0.523 0.477
E07.0 Hypersecretion of calcitonin
0.000 0.523 0.477
E06.4 Drug-induced thyroiditis
0.000 0.537 0.463
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.537 0.463
E06.0 Acute thyroiditis
0.000 0.537 0.463
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.540 0.460
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.547 0.453
E06.5 Other chronic thyroiditis
0.000 0.551 0.449
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.556 0.444
K90 Intestinal malabsorption
0.000 0.567 0.433
E03.5 Myxoedema coma
0.000 0.569 0.431
E03.4 Atrophy of thyroid (acquired)
0.000 0.569 0.431
E03.3 Postinfectious hypothyroidism
0.000 0.569 0.431
E03.1 Congenital hypothyroidism without goitre
0.000 0.580 0.420
E44.1 Mild protein-energy malnutrition
0.000 0.615 0.385
E44.0 Moderate protein-energy malnutrition
0.000 0.615 0.385
E03.8 Other specified hypothyroidism
0.000 0.624 0.376
E65-E68 Obesity and other hyperalimentation
0.000 0.638 0.361
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.643 0.357
E03.9 Hypothyroidism, unspecified
0.000 0.652 0.348
E07.9 Disorder of thyroid, unspecified
0.000 0.663 0.337
E50-E64 Other nutritional deficiencies
0.000 0.670 0.330
K90.3 Pancreatic steatorrhoea
0.000 0.689 0.310
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.689 0.310
K90.1 Tropical sprue
0.000 0.689 0.310
K90.8 Other intestinal malabsorption
0.000 0.696 0.303
E20-E35 Disorders of other endocrine glands
0.000 0.716 0.284
R31 Unspecified haematuria
0.266 0.734 0.000
E24 Cushing's syndrome
0.000 0.736 0.264
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.738 0.262
E67 Other hyperalimentation
0.000 0.741 0.259
E68 Sequelae of hyperalimentation
0.000 0.741 0.259
E21.3 Hyperparathyroidism, unspecified
0.000 0.745 0.255
K90.9 Intestinal malabsorption, unspecified
0.000 0.755 0.245
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.760 0.240
E51 Thiamine deficiency
0.000 0.762 0.238
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.763 0.237
E50 Vitamin A deficiency
0.000 0.763 0.237
E60 Dietary zinc deficiency
0.000 0.763 0.237
E59 Dietary selenium deficiency
0.000 0.763 0.237
E52 Niacin deficiency [pellagra]
0.000 0.763 0.237
E54 Ascorbic acid deficiency
0.000 0.767 0.233
E24.9 Cushing's syndrome, unspecified
0.000 0.771 0.229
E56 Other vitamin deficiencies
0.000 0.774 0.226
E65 Localised adiposity
0.000 0.777 0.223
E24.0 Pituitary-dependent Cushing's disease
0.000 0.779 0.221
E58 Dietary calcium deficiency
0.000 0.781 0.219
E63 Other nutritional deficiencies
0.000 0.785 0.215
E61 Deficiency of other nutrient elements
0.000 0.791 0.209
E24.2 Drug-induced Cushing's syndrome
0.000 0.791 0.209
E21.4 Other specified disorders of parathyroid gland
0.000 0.795 0.205
E25 Adrenogenital disorders
0.000 0.795 0.204
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.796 0.204
E32 Diseases of thymus
0.000 0.796 0.204
E30 Disorders of puberty, not elsewhere classified
0.000 0.796 0.204
C15-C26 Malignant neoplasms of digestive organs
0.000 0.796 0.204
C20 Malignant neoplasm of rectum
0.000 0.797 0.203
E55 Vitamin D deficiency
0.000 0.799 0.200
C15 Malignant neoplasm of oesophagus
0.000 0.800 0.200
E20 Hypoparathyroidism
0.000 0.803 0.197
E31 Polyglandular dysfunction
0.000 0.804 0.195
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.809 0.191
E21.2 Other hyperparathyroidism
0.000 0.810 0.190
E24.8 Other Cushing's syndrome
0.000 0.811 0.189
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.811 0.189
E24.3 Ectopic ACTH syndrome
0.000 0.811 0.189
E24.1 Nelson's syndrome
0.000 0.811 0.189
C15.5 Lower third of oesophagus
0.000 0.813 0.187
E67.8 Other specified hyperalimentation
0.000 0.814 0.186
E67.3 Hypervitaminosis D
0.000 0.814 0.186
E67.2 Megavitamin-B6 syndrome
0.000 0.814 0.186
E67.1 Hypercarotenaemia
0.000 0.814 0.186
E67.0 Hypervitaminosis A
0.000 0.814 0.186
E28 Ovarian dysfunction
0.000 0.817 0.183
E06.3 Autoimmune thyroiditis
0.000 0.822 0.178
E53 Deficiency of other B group vitamins
0.000 0.825 0.175
C25 Malignant neoplasm of pancreas
0.000 0.826 0.174
C15.4 Middle third of oesophagus
0.000 0.826 0.174
E51.2 Wernicke's encephalopathy
0.000 0.829 0.171
E51.9 Thiamine deficiency, unspecified
0.000 0.829 0.170
E51.8 Other manifestations of thiamine deficiency
0.000 0.829 0.170
E51.1 Beriberi
0.000 0.829 0.170
E50.9 Vitamin A deficiency, unspecified
0.000 0.830 0.170
E50.8 Other manifestations of vitamin A deficiency
0.000 0.830 0.170
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.830 0.170
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.830 0.170
E50.5 Vitamin A deficiency with night blindness
0.000 0.830 0.170
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.830 0.170
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.830 0.170
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.830 0.170
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.830 0.170
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.830 0.170
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.830 0.170
E64.8 Sequelae of other nutritional deficiencies
0.000 0.830 0.170
E64.3 Sequelae of rickets
0.000 0.830 0.170
E64.2 Sequelae of vitamin C deficiency
0.000 0.830 0.170
E64.1 Sequelae of vitamin A deficiency
0.000 0.830 0.170
E64.0 Sequelae of protein-energy malnutrition
0.000 0.830 0.170
E29 Testicular dysfunction
0.000 0.830 0.170
C15.9 Oesophagus, unspecified
0.000 0.832 0.168
E56.9 Vitamin deficiency, unspecified
0.000 0.838 0.162
E56.8 Deficiency of other vitamins
0.000 0.838 0.162
E56.0 Deficiency of vitamin E
0.000 0.838 0.162
C17 Malignant neoplasm of small intestine
0.000 0.840 0.160
E34 Other endocrine disorders
0.000 0.840 0.160
E14.9 Without complications
0.000 0.842 0.158
E83 Disorders of mineral metabolism
0.151 0.843 0.006
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.844 0.156
E63.8 Other specified nutritional deficiencies
0.000 0.846 0.154
E63.1 Imbalance of constituents of food intake
0.000 0.846 0.154
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.846 0.154
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.848 0.152
C17.0 Duodenum
0.000 0.848 0.152
E56.1 Deficiency of vitamin K
0.000 0.849 0.151
C15.0 Cervical part of oesophagus
0.000 0.850 0.150
E61.9 Deficiency of nutrient element, unspecified
0.000 0.850 0.150
E61.8 Deficiency of other specified nutrient elements
0.000 0.850 0.150
E61.7 Deficiency of multiple nutrient elements
0.000 0.850 0.150
E61.6 Vanadium deficiency
0.000 0.850 0.150
E61.5 Molybdenum deficiency
0.000 0.850 0.150
E61.4 Chromium deficiency
0.000 0.850 0.150
E61.3 Manganese deficiency
0.000 0.850 0.150
E61.0 Copper deficiency
0.000 0.850 0.150
C25.1 Body of pancreas
0.000 0.851 0.148
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.852 0.147
E25.9 Adrenogenital disorder, unspecified
0.000 0.853 0.147
E25.8 Other adrenogenital disorders
0.000 0.853 0.147
E30.9 Disorder of puberty, unspecified
0.000 0.854 0.146
E30.8 Other disorders of puberty
0.000 0.854 0.146
E30.1 Precocious puberty
0.000 0.854 0.146
E30.0 Delayed puberty
0.000 0.854 0.146
E32.9 Disease of thymus, unspecified
0.000 0.854 0.146
E32.8 Other diseases of thymus
0.000 0.854 0.146
E32.1 Abscess of thymus
0.000 0.854 0.146
E32.0 Persistent hyperplasia of thymus
0.000 0.854 0.146
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.854 0.146
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.854 0.146
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.854 0.146
C25.3 Pancreatic duct
0.000 0.854 0.146
E61.1 Iron deficiency
0.000 0.855 0.145
E55.0 Rickets, active
0.000 0.856 0.144
C15.8 Overlapping lesion of oesophagus
0.000 0.857 0.143
C15.2 Abdominal part of oesophagus
0.000 0.857 0.143
C25.2 Tail of pancreas
0.000 0.857 0.143
E20.8 Other hypoparathyroidism
0.000 0.859 0.141
E20.1 Pseudohypoparathyroidism
0.000 0.859 0.141
E20.0 Idiopathic hypoparathyroidism
0.000 0.859 0.141
C15.1 Thoracic part of oesophagus
0.000 0.859 0.140
E31.9 Polyglandular dysfunction, unspecified
0.000 0.860 0.140
E31.8 Other polyglandular dysfunction
0.000 0.860 0.140
E31.1 Polyglandular hyperfunction
0.000 0.860 0.140
C24.0 Extrahepatic bile duct
0.000 0.863 0.137
E53.9 Vitamin B deficiency, unspecified
0.000 0.863 0.136
E26 Hyperaldosteronism
0.000 0.864 0.136
E20.9 Hypoparathyroidism, unspecified
0.000 0.866 0.134
E63.9 Nutritional deficiency, unspecified
0.000 0.868 0.132
E31.0 Autoimmune polyglandular failure
0.000 0.868 0.132
C25.8 Overlapping lesion of pancreas
0.000 0.868 0.132
C15.3 Upper third of oesophagus
0.000 0.868 0.131
E28.9 Ovarian dysfunction, unspecified
0.000 0.869 0.131
E28.8 Other ovarian dysfunction
0.000 0.869 0.131
E28.1 Androgen excess
0.000 0.869 0.131
E28.0 Oestrogen excess
0.000 0.869 0.131
E28.2 Polycystic ovarian syndrome
0.000 0.870 0.130
E83.3 Disorders of phosphorus metabolism
0.128 0.871 0.001
E61.2 Magnesium deficiency
0.000 0.871 0.129
E11 Non-insulin-dependent diabetes mellitus
0.000 0.873 0.127
E22 Hyperfunction of pituitary gland
0.000 0.873 0.127
E53.1 Pyridoxine deficiency
0.000 0.874 0.126
E53.0 Riboflavin deficiency
0.000 0.874 0.126
C25.4 Endocrine pancreas
0.000 0.875 0.125
C25.9 Pancreas, unspecified
0.000 0.877 0.123
E29.9 Testicular dysfunction, unspecified
0.000 0.878 0.122
E29.8 Other testicular dysfunction
0.000 0.878 0.122
E29.0 Testicular hyperfunction
0.000 0.878 0.122
I83 Varicose veins of lower extremities
0.122 0.878 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.883 0.117
C21 Malignant neoplasm of anus and anal canal
0.000 0.883 0.117
E11.6 With other specified complications
0.000 0.884 0.116
C25.7 Other parts of pancreas
0.000 0.884 0.116
C17.8 Overlapping lesion of small intestine
0.000 0.885 0.115
C17.3 Meckel's diverticulum
0.000 0.885 0.115
E34.5 Androgen resistance syndrome
0.000 0.885 0.115
E34.4 Constitutional tall stature
0.000 0.885 0.115
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.885 0.115
E34.1 Other hypersecretion of intestinal hormones
0.000 0.885 0.115
E21.0 Primary hyperparathyroidism
0.000 0.885 0.115
E28.3 Primary ovarian failure
0.000 0.887 0.113
E83.8 Other disorders of mineral metabolism
0.108 0.888 0.004
E83.2 Disorders of zinc metabolism
0.108 0.888 0.004
E83.0 Disorders of copper metabolism
0.108 0.888 0.004
E83.9 Disorder of mineral metabolism, unspecified
0.107 0.889 0.004
C17.1 Jejunum
0.000 0.890 0.109
C24.8 Overlapping lesion of biliary tract
0.000 0.890 0.109
E55.9 Vitamin D deficiency, unspecified
0.000 0.893 0.107
E34.9 Endocrine disorder, unspecified
0.000 0.894 0.106
C24.9 Biliary tract, unspecified
0.000 0.894 0.106
E34.8 Other specified endocrine disorders
0.000 0.899 0.101
E34.0 Carcinoid syndrome
0.000 0.901 0.099
E26.8 Other hyperaldosteronism
0.000 0.902 0.097
E26.1 Secondary hyperaldosteronism
0.000 0.902 0.097
E11.2 With renal complications
0.000 0.904 0.096
E11.0 With coma
0.000 0.905 0.095
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.905 0.094
E22.1 Hyperprolactinaemia
0.000 0.906 0.094
M45.X9 Ankylosing spondylitis (Site unspecified)
0.094 0.906 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.908 0.092
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.908 0.092
E11.7 With multiple complications
0.000 0.909 0.091
E22.8 Other hyperfunction of pituitary gland
0.000 0.909 0.091
C23 Malignant neoplasm of gallbladder
0.000 0.909 0.091
E11.1 With ketoacidosis
0.000 0.911 0.089
E29.1 Testicular hypofunction
0.000 0.912 0.088
E26.9 Hyperaldosteronism, unspecified
0.001 0.913 0.086
C17.9 Small intestine, unspecified
0.000 0.914 0.086
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.914 0.086
C21.2 Cloacogenic zone
0.000 0.916 0.084
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.083 0.917 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.083 0.917 0.000
C17.2 Ileum
0.000 0.924 0.076
E11.8 With unspecified complications
0.000 0.924 0.076
E23 Hypofunction and other disorders of pituitary gland
0.000 0.925 0.075
C18 Malignant neoplasm of colon
0.000 0.930 0.070
C18.9 Colon, unspecified
0.000 0.930 0.070
C22.9 Liver, unspecified
0.000 0.931 0.069
E22.0 Acromegaly and pituitary gigantism
0.000 0.931 0.068
C26.8 Overlapping lesion of digestive system
0.000 0.932 0.068
C26.1 Spleen
0.000 0.932 0.068
C25.0 Head of pancreas
0.000 0.933 0.067
C22.7 Other specified carcinomas of liver
0.000 0.934 0.066
C22.4 Other sarcomas of liver
0.000 0.934 0.066
C22.3 Angiosarcoma of liver
0.000 0.934 0.066
C22.2 Hepatoblastoma
0.000 0.934 0.066
C21.0 Anus, unspecified
0.000 0.934 0.066
C18.1 Appendix
0.000 0.934 0.065
C21.1 Anal canal
0.000 0.936 0.064
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.938 0.062
C24.1 Ampulla of Vater
0.001 0.940 0.060
E23.7 Disorder of pituitary gland, unspecified
0.000 0.940 0.060
C22.1 Intrahepatic bile duct carcinoma
0.000 0.941 0.059
E27 Other disorders of adrenal gland
0.000 0.946 0.054
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.946 0.054
E23.1 Drug-induced hypopituitarism
0.000 0.946 0.054
E83.4 Disorders of magnesium metabolism
0.051 0.946 0.003
E26.0 Primary hyperaldosteronism
0.001 0.947 0.053
C18.8 Overlapping lesion of colon
0.000 0.947 0.053
Z71.8 Other specified counselling
0.051 0.949 0.000
C26.9 Ill-defined sites within the digestive system
0.000 0.950 0.049
C16 Malignant neoplasm of stomach
0.000 0.951 0.049
E04 Other non-toxic goitre
0.003 0.952 0.045
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.952 0.048
C26.0 Intestinal tract, part unspecified
0.000 0.952 0.048
E11.5 With peripheral circulatory complications
0.000 0.956 0.044
E11.3 With ophthalmic complications
0.000 0.957 0.043
M45 Ankylosing spondylitis
0.043 0.957 0.000
C18.4 Transverse colon
0.000 0.957 0.043
S02.4 Fracture of malar and maxillary bones
0.000 0.959 0.041
E70-E90 Metabolic disorders
0.002 0.959 0.039
E27.1 Primary adrenocortical insufficiency
0.000 0.960 0.040
E27.5 Adrenomedullary hyperfunction
0.000 0.961 0.039
E27.0 Other adrenocortical overactivity
0.000 0.961 0.039
I83.1 Varicose veins of lower extremities with inflammation
0.038 0.962 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.963 0.037
E78.2 Mixed hyperlipidaemia
0.000 0.964 0.036
S02 Fracture of skull and facial bones
0.000 0.964 0.036
C16.5 Lesser curvature of stomach, unspecified
0.000 0.964 0.036
C18.7 Sigmoid colon
0.000 0.965 0.035
E27.9 Disorder of adrenal gland, unspecified
0.000 0.965 0.035
E04.8 Other specified non-toxic goitre
0.002 0.965 0.033
M45.X2 Ankylosing spondylitis (Cervical region)
0.034 0.966 0.000
E23.6 Other disorders of pituitary gland
0.001 0.966 0.034
E27.2 Addisonian crisis
0.000 0.967 0.033
C18.6 Descending colon
0.000 0.967 0.033
C16.0 Cardia
0.000 0.967 0.033
C16.8 Overlapping lesion of stomach
0.000 0.967 0.033
C16.2 Body of stomach
0.000 0.967 0.033
E23.2 Diabetes insipidus
0.000 0.967 0.033
E53.8 Deficiency of other specified B group vitamins
0.000 0.967 0.033
E78.5 Hyperlipidaemia, unspecified
0.000 0.967 0.033
M45.X6 Ankylosing spondylitis (Lumbar region)
0.033 0.967 0.000
C16.6 Greater curvature of stomach, unspecified
0.000 0.967 0.032
E78.1 Pure hyperglyceridaemia
0.000 0.969 0.031
C16.4 Pylorus
0.000 0.969 0.031
S02.8 Fractures of other skull and facial bones
0.000 0.969 0.031
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.031 0.969 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.031 0.969 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.031 0.969 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.031 0.969 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.031 0.969 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.031 0.969 0.000
E73 Lactose intolerance
0.001 0.969 0.030
S02.0 Fracture of vault of skull
0.000 0.969 0.031
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.969 0.029
E74 Other disorders of carbohydrate metabolism
0.001 0.970 0.029
S02.3 Fracture of orbital floor
0.000 0.970 0.030
S02.6 Fracture of mandible
0.000 0.970 0.030
C16.1 Fundus of stomach
0.000 0.970 0.030
E78.6 Lipoprotein deficiency
0.000 0.970 0.030
E77 Disorders of glycoprotein metabolism
0.001 0.971 0.028
E76 Disorders of glycosaminoglycan metabolism
0.001 0.971 0.028
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.971 0.028
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.971 0.028
S02.5 Fracture of tooth
0.000 0.971 0.029
C16.9 Stomach, unspecified
0.000 0.971 0.029
E85 Amyloidosis
0.001 0.971 0.028
S02.7 Multiple fractures involving skull and facial bones
0.000 0.971 0.029
E78.3 Hyperchylomicronaemia
0.000 0.971 0.028
E70 Disorders of aromatic amino-acid metabolism
0.001 0.972 0.027
C18.3 Hepatic flexure
0.000 0.972 0.028
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.972 0.027
K90-K93 Other diseases of the digestive system
0.000 0.972 0.027
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.973 0.027
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.973 0.027
E72 Other disorders of amino-acid metabolism
0.002 0.973 0.026
E79 Disorders of purine and pyrimidine metabolism
0.002 0.973 0.026
S02.00 Fracture of vault of skull (closed)
0.000 0.973 0.027
C16.3 Pyloric antrum
0.000 0.973 0.027
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.973 0.027
S02.2 Fracture of nasal bones
0.000 0.974 0.026
E84 Cystic fibrosis
0.002 0.974 0.025
E27.8 Other specified disorders of adrenal gland
0.000 0.974 0.026
S02.30 Fracture of orbital floor (closed)
0.000 0.974 0.026
S02.60 Fracture of mandible (closed)
0.000 0.975 0.025
E04.0 Non-toxic diffuse goitre
0.003 0.975 0.023
E88 Other metabolic disorders
0.001 0.975 0.024
E66 Obesity
0.000 0.975 0.024
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.976 0.024
S02.50 Fracture of tooth (closed)
0.000 0.976 0.024
E73.9 Lactose intolerance, unspecified
0.001 0.976 0.023
E11.9 Without complications
0.000 0.976 0.024
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.976 0.024
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.024 0.976 0.000
E78.4 Other hyperlipidaemia
0.000 0.976 0.023
E11.4 With neurological complications
0.000 0.976 0.023
E23.0 Hypopituitarism
0.000 0.976 0.023
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.976 0.023
E85.4 Organ-limited amyloidosis
0.001 0.977 0.023
E75.5 Other lipid storage disorders
0.001 0.977 0.022
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.977 0.023
E75.2 Other sphingolipidosis
0.001 0.977 0.022
S02.81 Fractures of other skull and facial bones (open)
0.000 0.977 0.022
E73.8 Other lactose intolerance
0.001 0.978 0.022
E73.1 Secondary lactase deficiency
0.001 0.978 0.022
E73.0 Congenital lactase deficiency
0.001 0.978 0.022
S02.01 Fracture of vault of skull (open)
0.000 0.978 0.022
E75.6 Lipid storage disorder, unspecified
0.001 0.978 0.021
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.978 0.021
E75.3 Sphingolipidosis, unspecified
0.001 0.978 0.021
E75.1 Other gangliosidosis
0.001 0.978 0.021
E75.0 GM2 gangliosidosis
0.001 0.978 0.021
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.978 0.021
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.978 0.021
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.978 0.021
E74.2 Disorders of galactose metabolism
0.001 0.978 0.021
E74.1 Disorders of fructose metabolism
0.001 0.978 0.021
S02.21 Fracture of nasal bones (open)
0.000 0.978 0.022
S02.31 Fracture of orbital floor (open)
0.000 0.978 0.022
S02.61 Fracture of mandible (open)
0.000 0.978 0.022
E74.0 Glycogen storage disease
0.001 0.978 0.021
E71.3 Disorders of fatty-acid metabolism
0.001 0.979 0.020
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.979 0.020
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.979 0.020
E71.0 Maple-syrup-urine disease
0.001 0.979 0.020
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.979 0.020
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.979 0.020
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.979 0.020
E76.2 Other mucopolysaccharidoses
0.001 0.979 0.020
E76.1 Mucopolysaccharidosis, type II
0.001 0.979 0.020
E76.0 Mucopolysaccharidosis, type I
0.001 0.979 0.020
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.979 0.020
E77.8 Other disorders of glycoprotein metabolism
0.001 0.979 0.020
E77.1 Defects in glycoprotein degradation
0.001 0.979 0.020
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.979 0.020
E85.3 Secondary systemic amyloidosis
0.001 0.979 0.021
S02.51 Fracture of tooth (open)
0.000 0.979 0.021
E85.8 Other amyloidosis
0.001 0.979 0.020
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.979 0.020
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.979 0.020
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.979 0.020
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.979 0.021
C22.0 Liver cell carcinoma
0.001 0.979 0.020
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.980 0.019
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.980 0.019
E70.2 Disorders of tyrosine metabolism
0.001 0.980 0.019
E70.1 Other hyperphenylalaninaemias
0.001 0.980 0.019
E70.0 Classical phenylketonuria
0.001 0.980 0.019
H40.2 Primary angle-closure glaucoma
0.020 0.980 0.000
S02.1 Fracture of base of skull
0.000 0.980 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.980 0.020
E88.9 Metabolic disorder, unspecified
0.001 0.980 0.019
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.980 0.019
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.980 0.019
E72.5 Disorders of glycine metabolism
0.001 0.980 0.019
E72.4 Disorders of ornithine metabolism
0.001 0.980 0.019
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.980 0.019
E72.2 Disorders of urea cycle metabolism
0.001 0.980 0.019
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.980 0.019
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.980 0.019
E79.1 Lesch-Nyhan syndrome
0.001 0.980 0.019
E72.0 Disorders of amino-acid transport
0.001 0.981 0.018
E70.3 Albinism
0.001 0.981 0.018
E84.8 Cystic fibrosis with other manifestations
0.001 0.981 0.018
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.981 0.018
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.981 0.018
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.981 0.018
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.982 0.017
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.982 0.017
E88.2 Lipomatosis, not elsewhere classified
0.001 0.982 0.017

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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