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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130932
log Bayes Factor = 76.6809
Chromosome 6   position 31,133,943  (GRCh37) Explore rs3130932 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.003 0.997
E14 Unspecified diabetes mellitus
0.000 0.003 0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.004 0.996
G35 Multiple sclerosis
0.996 0.004 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.023 0.977
K51.9 Ulcerative colitis, unspecified
0.967 0.033 0.000
E14.9 Without complications
0.000 0.033 0.967
E14.3 With ophthalmic complications
0.000 0.034 0.966
K51 Ulcerative colitis
0.958 0.042 0.000
E10.3 With ophthalmic complications
0.000 0.044 0.956
L40 Psoriasis
0.000 0.049 0.951
E11 Non-insulin-dependent diabetes mellitus
0.000 0.053 0.947
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.055 0.945
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.059 0.941
K51.2 Ulcerative (chronic) proctitis
0.938 0.062 0.000
E11.9 Without complications
0.000 0.064 0.936
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.074 0.926
K51.4 Pseudopolyposis of colon
0.922 0.078 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.086 0.914
K51.3 Ulcerative (chronic) rectosigmoiditis
0.882 0.118 0.000
L40.5 Arthropathic psoriasis
0.000 0.127 0.873
E11.1 With ketoacidosis
0.000 0.133 0.867
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.146 0.854
L40.0 Psoriasis vulgaris
0.000 0.157 0.843
E13 Other specified diabetes mellitus
0.000 0.165 0.835
G35-G37 Demyelinating diseases of the central nervous system
0.823 0.177 0.000
E03 Other hypothyroidism
0.000 0.183 0.817
E03.9 Hypothyroidism, unspecified
0.000 0.186 0.814
E00-E07 Disorders of thyroid gland
0.000 0.186 0.814
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.189 0.811
L40.8 Other psoriasis
0.000 0.195 0.805
E05.9 Thyrotoxicosis, unspecified
0.000 0.201 0.799
E10.8 With unspecified complications
0.000 0.201 0.799
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.201 0.799
E10.1 With ketoacidosis
0.000 0.212 0.788
E10.6 With other specified complications
0.000 0.217 0.783
E14.4 With neurological complications
0.000 0.223 0.777
L40.1 Generalised pustular psoriasis
0.000 0.223 0.777
E10.0 With coma
0.000 0.223 0.777
G37 Other demyelinating diseases of central nervous system
0.775 0.225 0.000
E14.5 With peripheral circulatory complications
0.000 0.233 0.767
K51.5 Mucosal proctocolitis
0.761 0.239 0.000
E14.1 With ketoacidosis
0.000 0.239 0.760
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.243 0.757
E14.6 With other specified complications
0.000 0.245 0.755
E83.1 Disorders of iron metabolism
0.751 0.249 0.000
K90 Intestinal malabsorption
0.000 0.258 0.742
E11.0 With coma
0.000 0.273 0.727
G37.9 Demyelinating disease of central nervous system, unspecified
0.725 0.275 0.000
E13.9 Without complications
0.000 0.275 0.725
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.285 0.715
E14.0 With coma
0.000 0.285 0.715
E03.8 Other specified hypothyroidism
0.000 0.286 0.714
J45.9 Asthma, unspecified
0.000 0.288 0.712
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.288 0.712
E14.2 Withrenal complications
0.000 0.295 0.705
L40.4 Guttate psoriasis
0.000 0.312 0.687
L40.2 Acrodermatitis continua
0.000 0.318 0.682
K51.1 Ulcerative (chronic) ileocolitis
0.679 0.321 0.000
E11.7 With multiple complications
0.000 0.321 0.679
E16 Other disorders of pancreatic internal secretion
0.000 0.349 0.651
G36 Other acute disseminated demyelination
0.651 0.349 0.000
E11.4 With neurological complications
0.000 0.355 0.645
K90.9 Intestinal malabsorption, unspecified
0.000 0.357 0.643
J47 Bronchiectasis
0.636 0.364 0.000
E14.8 With unspecified complications
0.000 0.366 0.634
E07 Other disorders of thyroid
0.000 0.370 0.630
E10.2 With renal complications
0.000 0.373 0.627
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.374 0.626
E10.4 With neurological complications
0.000 0.380 0.620
E11.2 With renal complications
0.000 0.381 0.619
E10.5 With peripheral circulatory complications
0.000 0.384 0.616
G37.8 Other specified demyelinating diseases of central nervous system
0.611 0.388 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.392 0.608
E11.5 With peripheral circulatory complications
0.000 0.394 0.606
E13.8 With unspecified complications
0.000 0.401 0.599
E13.7 With multiple complications
0.000 0.401 0.599
E13.6 With other specified complications
0.000 0.401 0.599
E13.5 With peripheral circulatory complications
0.000 0.401 0.599
E13.4 With neurological complications
0.000 0.401 0.599
E13.2 With renal complications
0.000 0.401 0.599
E13.1 With ketoacidosis
0.000 0.401 0.599
E13.0 With coma
0.000 0.401 0.599
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.407 0.593
E11.8 With unspecified complications
0.000 0.408 0.591
E16.2 Hypoglycaemia, unspecified
0.000 0.413 0.587
E03.5 Myxoedema coma
0.000 0.414 0.586
E03.4 Atrophy of thyroid (acquired)
0.000 0.414 0.586
E03.3 Postinfectious hypothyroidism
0.000 0.414 0.586
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.414 0.586
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.416 0.584
E00 Congenital iodine-deficiency syndrome
0.000 0.416 0.584
E13.3 With ophthalmic complications
0.000 0.418 0.582
E83 Disorders of mineral metabolism
0.573 0.426 0.000
E05.5 Thyroid crisis or storm
0.000 0.427 0.573
E05.4 Thyrotoxicosis factitia
0.000 0.427 0.573
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.427 0.573
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.427 0.573
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.570 0.430 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.431 0.568
G37.5 Concentric sclerosis [Balo]
0.555 0.444 0.000
G37.4 Subacute necrotising myelitis
0.555 0.444 0.000
G37.2 Central pontine myelinolysis
0.555 0.444 0.000
G37.1 Central demyelination of corpus callosum
0.555 0.444 0.000
G37.0 Diffuse sclerosis
0.555 0.444 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.468 0.532
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.468 0.532
K90.1 Tropical sprue
0.000 0.468 0.532
G36.0 Neuromyelitis optica [Devic]
0.527 0.473 0.000
E83.3 Disorders of phosphorus metabolism
0.520 0.480 0.000
K90.8 Other intestinal malabsorption
0.000 0.483 0.517
E15 Nondiabetic hypoglycaemic coma
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E16.1 Other hypoglycaemia
0.000 0.488 0.512
E03.1 Congenital hypothyroidism without goitre
0.000 0.490 0.510
K51.8 Other ulcerative colitis
0.509 0.491 0.000
E40-E46 Malnutrition
0.000 0.495 0.505
E83.4 Disorders of magnesium metabolism
0.481 0.519 0.000
E07.8 Other specified disorders of thyroid
0.000 0.521 0.479
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.522 0.478
E07.9 Disorder of thyroid, unspecified
0.000 0.527 0.473
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.530 0.470
E20-E35 Disorders of other endocrine glands
0.000 0.531 0.469
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.532 0.468
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.533 0.467
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.533 0.467
E16.4 Abnormal secretion of gastrin
0.000 0.533 0.467
E16.3 Increased secretion of glucagon
0.000 0.533 0.467
G36.9 Acute disseminated demyelination, unspecified
0.466 0.533 0.000
G36.8 Other specified acute disseminated demyelination
0.466 0.533 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.466 0.533 0.000
E05.8 Other thyrotoxicosis
0.000 0.534 0.466
E07.1 Dyshormogenetic goitre
0.000 0.548 0.451
E07.0 Hypersecretion of calcitonin
0.000 0.548 0.451
M06 Other rheumatoid arthritis
0.000 0.566 0.434
E83.9 Disorder of mineral metabolism, unspecified
0.426 0.574 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.577 0.423
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.581 0.418
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.581 0.418
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.581 0.418
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.581 0.418
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.581 0.418
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.581 0.418
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.581 0.418
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.581 0.418
E83.8 Other disorders of mineral metabolism
0.411 0.589 0.000
E83.2 Disorders of zinc metabolism
0.411 0.589 0.000
E83.0 Disorders of copper metabolism
0.411 0.589 0.000
E28 Ovarian dysfunction
0.000 0.592 0.408
M06.3 Rheumatoid nodule
0.000 0.608 0.392
E24 Cushing's syndrome
0.000 0.612 0.388
E11.6 With other specified complications
0.001 0.620 0.379
E28.2 Polycystic ovarian syndrome
0.000 0.621 0.379
K51.0 Ulcerative (chronic) enterocolitis
0.367 0.633 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.637 0.362
E45 Retarded development following protein-energy malnutrition
0.000 0.637 0.362
E43 Unspecified severe protein-energy malnutrition
0.000 0.637 0.362
E42 Marasmic kwashiorkor
0.000 0.637 0.362
E41 Nutritional marasmus
0.000 0.637 0.362
E40 Kwashiorkor
0.000 0.637 0.362
E83.5 Disorders of calcium metabolism
0.357 0.643 0.000
E23.2 Diabetes insipidus
0.000 0.647 0.353
E23.7 Disorder of pituitary gland, unspecified
0.000 0.648 0.352
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.650 0.350
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.659 0.341
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.660 0.339
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.663 0.336
E32 Diseases of thymus
0.000 0.663 0.336
E31 Polyglandular dysfunction
0.000 0.663 0.336
E30 Disorders of puberty, not elsewhere classified
0.000 0.663 0.336
E25 Adrenogenital disorders
0.000 0.663 0.336
M06.34 Rheumatoid nodule (Hand)
0.000 0.670 0.330
E23.0 Hypopituitarism
0.000 0.681 0.319
E24.2 Drug-induced Cushing's syndrome
0.000 0.682 0.318
E23.6 Other disorders of pituitary gland
0.000 0.683 0.317
M06.2 Rheumatoid bursitis
0.000 0.688 0.311
M06.1 Adult-onset Still's disease
0.000 0.688 0.311
E21.3 Hyperparathyroidism, unspecified
0.000 0.689 0.311
E29 Testicular dysfunction
0.000 0.689 0.311
J45 Asthma
0.011 0.689 0.300
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.696 0.304
E23.1 Drug-induced hypopituitarism
0.000 0.696 0.304
E24.9 Cushing's syndrome, unspecified
0.000 0.698 0.302
M06.4 Inflammatory polyarthropathy
0.000 0.699 0.301
E20 Hypoparathyroidism
0.000 0.699 0.301
M06.8 Other specified rheumatoid arthritis
0.000 0.700 0.299
E28.9 Ovarian dysfunction, unspecified
0.000 0.707 0.292
E28.8 Other ovarian dysfunction
0.000 0.707 0.292
E28.1 Androgen excess
0.000 0.707 0.292
E28.0 Oestrogen excess
0.000 0.707 0.292
E46 Unspecified protein-energy malnutrition
0.000 0.714 0.286
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.719 0.281
M06.38 Rheumatoid nodule (Other)
0.000 0.719 0.281
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.719 0.281
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.719 0.281
M06.33 Rheumatoid nodule (Forearm)
0.000 0.719 0.281
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.719 0.281
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.720 0.280
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.722 0.278
E24.3 Ectopic ACTH syndrome
0.000 0.722 0.278
E24.1 Nelson's syndrome
0.000 0.722 0.278
E24.0 Pituitary-dependent Cushing's disease
0.000 0.722 0.278
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.722 0.278
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.725 0.275
E24.8 Other Cushing's syndrome
0.000 0.728 0.272
E44.1 Mild protein-energy malnutrition
0.000 0.740 0.260
E44.0 Moderate protein-energy malnutrition
0.000 0.740 0.260
E22 Hyperfunction of pituitary gland
0.000 0.743 0.257
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.745 0.255
E21.4 Other specified disorders of parathyroid gland
0.000 0.749 0.251
E21.2 Other hyperparathyroidism
0.000 0.749 0.251
L40-L45 Papulosquamous disorders
0.000 0.755 0.245
E26 Hyperaldosteronism
0.000 0.757 0.243
E25.9 Adrenogenital disorder, unspecified
0.000 0.758 0.241
E25.8 Other adrenogenital disorders
0.000 0.758 0.241
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.758 0.241
E30.9 Disorder of puberty, unspecified
0.000 0.758 0.241
E30.8 Other disorders of puberty
0.000 0.758 0.241
E30.1 Precocious puberty
0.000 0.758 0.241
E30.0 Delayed puberty
0.000 0.758 0.241
E31.9 Polyglandular dysfunction, unspecified
0.000 0.758 0.241
E31.8 Other polyglandular dysfunction
0.000 0.758 0.241
E31.1 Polyglandular hyperfunction
0.000 0.758 0.241
E31.0 Autoimmune polyglandular failure
0.000 0.758 0.241
E32.9 Disease of thymus, unspecified
0.000 0.758 0.241
E32.8 Other diseases of thymus
0.000 0.758 0.241
E32.1 Abscess of thymus
0.000 0.758 0.241
E32.0 Persistent hyperplasia of thymus
0.000 0.758 0.241
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.758 0.241
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.758 0.241
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.758 0.241
K91.4 Colostomy and enterostomy malfunction
0.240 0.760 0.000
J45.8 Mixed asthma
0.007 0.762 0.231
E28.3 Primary ovarian failure
0.000 0.766 0.233
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.769 0.230
J45.1 Nonallergic asthma
0.007 0.776 0.216
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.776 0.223
M06.18 Adult-onset Still's disease (Other)
0.000 0.776 0.223
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.776 0.223
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.776 0.223
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.776 0.223
M06.14 Adult-onset Still's disease (Hand)
0.000 0.776 0.223
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.776 0.223
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.776 0.223
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.776 0.223
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.776 0.223
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.776 0.223
M06.28 Rheumatoid bursitis (Other)
0.000 0.776 0.223
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.776 0.223
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.776 0.223
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.776 0.223
M06.24 Rheumatoid bursitis (Hand)
0.000 0.776 0.223
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.776 0.223
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.776 0.223
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.776 0.223
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.776 0.223
E29.9 Testicular dysfunction, unspecified
0.000 0.777 0.223
E29.8 Other testicular dysfunction
0.000 0.777 0.223
E29.0 Testicular hyperfunction
0.000 0.777 0.223
E65-E68 Obesity and other hyperalimentation
0.002 0.777 0.222
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.784 0.216
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.784 0.216
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.784 0.216
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.784 0.216
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.784 0.216
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.784 0.216
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.784 0.216
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.784 0.216
E20.8 Other hypoparathyroidism
0.000 0.784 0.216
E20.1 Pseudohypoparathyroidism
0.000 0.784 0.216
E20.0 Idiopathic hypoparathyroidism
0.000 0.784 0.216
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.785 0.215
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.785 0.215
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.785 0.215
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.785 0.215
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.785 0.215
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.785 0.215
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.785 0.215
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.785 0.215
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.785 0.215
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.797 0.203
E34 Other endocrine disorders
0.000 0.802 0.197
E29.1 Testicular hypofunction
0.000 0.803 0.197
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.805 0.195
E11.3 With ophthalmic complications
0.000 0.813 0.187
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.813 0.187
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.816 0.184
E22.8 Other hyperfunction of pituitary gland
0.000 0.816 0.184
E06 Thyroiditis
0.002 0.819 0.179
L42 Pityriasis rosea
0.000 0.819 0.181
E20.9 Hypoparathyroidism, unspecified
0.000 0.820 0.180
L44 Other papulosquamous disorders
0.000 0.824 0.175
L41 Parapsoriasis
0.000 0.824 0.175
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.824 0.175
E26.8 Other hyperaldosteronism
0.000 0.826 0.174
E26.1 Secondary hyperaldosteronism
0.000 0.826 0.174
E22.1 Hyperprolactinaemia
0.000 0.828 0.172
E67 Other hyperalimentation
0.001 0.840 0.159
E68 Sequelae of hyperalimentation
0.001 0.840 0.159
J45.0 Predominantly allergic asthma
0.002 0.841 0.156
E26.9 Hyperaldosteronism, unspecified
0.000 0.846 0.154
E50-E64 Other nutritional deficiencies
0.000 0.852 0.147
E34.5 Androgen resistance syndrome
0.000 0.858 0.141
E34.4 Constitutional tall stature
0.000 0.858 0.141
E34.3 Short stature, not elsewhere classified
0.000 0.858 0.141
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.858 0.141
E34.1 Other hypersecretion of intestinal hormones
0.000 0.858 0.141
E27 Other disorders of adrenal gland
0.000 0.858 0.141
M06.0 Seronegative rheumatoid arthritis
0.000 0.864 0.135
E34.8 Other specified endocrine disorders
0.000 0.867 0.133
J40-J47 Chronic lower respiratory diseases
0.062 0.869 0.069
E06.4 Drug-induced thyroiditis
0.002 0.870 0.128
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.002 0.870 0.128
E06.0 Acute thyroiditis
0.002 0.870 0.128
E06.5 Other chronic thyroiditis
0.002 0.871 0.127
L41.9 Parapsoriasis, unspecified
0.000 0.874 0.126
L41.8 Other parapsoriasis
0.000 0.874 0.126
L41.5 Retiform parapsoriasis
0.000 0.874 0.126
L41.4 Large plaque parapsoriasis
0.000 0.874 0.126
L41.3 Small plaque parapsoriasis
0.000 0.874 0.126
L41.2 Lymphomatoid papulosis
0.000 0.874 0.126
L41.1 Pityriasis lichenoides chronica
0.000 0.874 0.126
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.874 0.126
L44.9 Papulosquamous disorder, unspecified
0.000 0.874 0.126
L44.8 Other specified papulosquamous disorders
0.000 0.874 0.126
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.874 0.126
L44.3 Lichen ruber moniliformis
0.000 0.874 0.126
L44.2 Lichen striatus
0.000 0.874 0.126
L44.1 Lichen nitidus
0.000 0.874 0.126
L44.0 Pityriasis rubra pilaris
0.000 0.874 0.126
E26.0 Primary hyperaldosteronism
0.001 0.883 0.117
E34.9 Endocrine disorder, unspecified
0.000 0.883 0.117
E67.8 Other specified hyperalimentation
0.001 0.885 0.114
E67.3 Hypervitaminosis D
0.001 0.885 0.114
E67.2 Megavitamin-B6 syndrome
0.001 0.885 0.114
E67.1 Hypercarotenaemia
0.001 0.885 0.114
E67.0 Hypervitaminosis A
0.001 0.885 0.114
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.886 0.114
E27.9 Disorder of adrenal gland, unspecified
0.000 0.888 0.112
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.894 0.106
E63 Other nutritional deficiencies
0.000 0.894 0.106
E50 Vitamin A deficiency
0.000 0.894 0.106
E60 Dietary zinc deficiency
0.000 0.894 0.106
E59 Dietary selenium deficiency
0.000 0.894 0.106
E54 Ascorbic acid deficiency
0.000 0.894 0.106
E52 Niacin deficiency [pellagra]
0.000 0.894 0.106
E22.0 Acromegaly and pituitary gigantism
0.000 0.896 0.103
E06.1 Subacute thyroiditis
0.002 0.897 0.101
E56 Other vitamin deficiencies
0.000 0.897 0.102
E27.5 Adrenomedullary hyperfunction
0.000 0.898 0.102
E27.0 Other adrenocortical overactivity
0.000 0.898 0.102
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.903 0.097
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.903 0.097
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.903 0.097
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.903 0.097
E58 Dietary calcium deficiency
0.000 0.903 0.097
E51 Thiamine deficiency
0.000 0.904 0.096
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.907 0.092
J41 Simple and mucopurulent chronic bronchitis
0.046 0.908 0.047
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.908 0.092
L43 Lichen planus
0.000 0.910 0.090
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.911 0.089
I10 Essential (primary) hypertension
0.000 0.913 0.087
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.915 0.085
K50-K52 Noninfective enteritis and colitis
0.084 0.916 0.000
E65 Localised adiposity
0.002 0.917 0.081
E34.0 Carcinoid syndrome
0.001 0.919 0.080
J46 Status asthmaticus
0.004 0.920 0.076
K90-K93 Other diseases of the digestive system
0.001 0.920 0.078
E55 Vitamin D deficiency
0.000 0.920 0.079
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.922 0.077
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.923 0.077
E50.9 Vitamin A deficiency, unspecified
0.000 0.924 0.076
E50.8 Other manifestations of vitamin A deficiency
0.000 0.924 0.076
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.924 0.076
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.924 0.076
E50.5 Vitamin A deficiency with night blindness
0.000 0.924 0.076
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.924 0.076
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.924 0.076
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.924 0.076
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.924 0.076
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.924 0.076
E63.9 Nutritional deficiency, unspecified
0.000 0.924 0.076
E63.8 Other specified nutritional deficiencies
0.000 0.924 0.076
E63.1 Imbalance of constituents of food intake
0.000 0.924 0.076
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.924 0.076
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.924 0.076
E64.8 Sequelae of other nutritional deficiencies
0.000 0.924 0.076
E64.3 Sequelae of rickets
0.000 0.924 0.076
E64.2 Sequelae of vitamin C deficiency
0.000 0.924 0.076
E64.1 Sequelae of vitamin A deficiency
0.000 0.924 0.076
E64.0 Sequelae of protein-energy malnutrition
0.000 0.924 0.076
E56.9 Vitamin deficiency, unspecified
0.000 0.926 0.073
E56.8 Deficiency of other vitamins
0.000 0.926 0.073
E56.0 Deficiency of vitamin E
0.000 0.926 0.073
E61 Deficiency of other nutrient elements
0.000 0.929 0.071
E27.2 Addisonian crisis
0.000 0.929 0.071
E56.1 Deficiency of vitamin K
0.000 0.930 0.070
E51.9 Thiamine deficiency, unspecified
0.000 0.931 0.069
E51.8 Other manifestations of thiamine deficiency
0.000 0.931 0.069
E51.1 Beriberi
0.000 0.931 0.069
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.933 0.067
E27.8 Other specified disorders of adrenal gland
0.000 0.933 0.067
J42 Unspecified chronic bronchitis
0.051 0.933 0.016
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.033 0.933 0.034
J41.1 Mucopurulent chronic bronchitis
0.033 0.933 0.034
E06.9 Thyroiditis, unspecified
0.003 0.935 0.062
J41.0 Simple chronic bronchitis
0.034 0.935 0.031
L43.3 Subacute (active) lichen planus
0.000 0.935 0.064
L43.2 Lichenoid drug reaction
0.000 0.935 0.064
L43.1 Bullous lichen planus
0.000 0.935 0.064
L43.0 Hypertrophic lichen planus
0.000 0.935 0.064
J43 Emphysema
0.026 0.936 0.039
J40 Bronchitis, not specified as acute or chronic
0.059 0.938 0.003
E51.2 Wernicke's encephalopathy
0.001 0.940 0.059
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.943 0.056
E55.0 Rickets, active
0.000 0.943 0.057
K60.2 Anal fissure, unspecified
0.000 0.943 0.057
E27.1 Primary adrenocortical insufficiency
0.000 0.945 0.055
E06.3 Autoimmune thyroiditis
0.002 0.946 0.052
E61.9 Deficiency of nutrient element, unspecified
0.000 0.949 0.051
E61.8 Deficiency of other specified nutrient elements
0.000 0.949 0.051
E61.7 Deficiency of multiple nutrient elements
0.000 0.949 0.051
E61.6 Vanadium deficiency
0.000 0.949 0.051
E61.5 Molybdenum deficiency
0.000 0.949 0.051
E61.4 Chromium deficiency
0.000 0.949 0.051
E61.3 Manganese deficiency
0.000 0.949 0.051
E61.0 Copper deficiency
0.000 0.949 0.051
E53 Deficiency of other B group vitamins
0.000 0.952 0.048
I10-I15 Hypertensive diseases
0.000 0.952 0.048
J43.1 Panlobular emphysema
0.019 0.954 0.028
J43.0 MacLeod's syndrome
0.019 0.954 0.028
E04 Other non-toxic goitre
0.002 0.954 0.044
J43.8 Other emphysema
0.017 0.954 0.029
E21.0 Primary hyperparathyroidism
0.000 0.955 0.044
I12 Hypertensive renal disease
0.000 0.958 0.042
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.959 0.040
K93.1 Megacolon in Chagas' disease
0.001 0.959 0.040
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.959 0.040
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.041 0.959 0.000
J43.2 Centrilobular emphysema
0.020 0.959 0.021
L43.8 Other lichen planus
0.001 0.960 0.039
E61.2 Magnesium deficiency
0.001 0.960 0.039
I11 Hypertensive heart disease
0.000 0.961 0.039
E61.1 Iron deficiency
0.000 0.963 0.037
I12.9 Hypertensive renal disease without renal failure
0.000 0.965 0.035
E53.1 Pyridoxine deficiency
0.000 0.965 0.035
E53.0 Riboflavin deficiency
0.000 0.965 0.035
I12.0 Hypertensive renal disease with renal failure
0.000 0.965 0.035
E66 Obesity
0.002 0.966 0.033
L43.9 Lichen planus, unspecified
0.000 0.966 0.033
E04.8 Other specified non-toxic goitre
0.002 0.967 0.032
M05-M14 Inflammatory polyarthropathies
0.000 0.968 0.032
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.969 0.031
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.010 0.969 0.021
I15 Secondary hypertension
0.000 0.969 0.031
E55.9 Vitamin D deficiency, unspecified
0.000 0.969 0.031
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.970 0.030
I13 Hypertensive heart and renal disease
0.000 0.971 0.029
J98.4 Other disorders of lung
0.000 0.971 0.029
M07 Psoriatic and enteropathic arthropathies
0.000 0.971 0.029
E70-E90 Metabolic disorders
0.002 0.971 0.027
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.972 0.028
E04.0 Non-toxic diffuse goitre
0.002 0.972 0.026
M07.3 Other psoriatic arthropathies
0.000 0.973 0.027
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.973 0.026
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.026 0.974 0.000
K52 Other non-infective gastro-enteritis and colitis
0.026 0.974 0.000
I15.9 Seconday hypertension, unspecified
0.000 0.975 0.025
E66.1 Drug-induced obesity
0.001 0.975 0.024
K92 Other diseases of digestive system
0.000 0.975 0.025
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.025 0.975 0.000
E53.9 Vitamin B deficiency, unspecified
0.001 0.975 0.024
J43.9 Emphysema, unspecified
0.001 0.975 0.024
K56.2 Volvulus
0.024 0.976 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.024 0.976 0.000
E88 Other metabolic disorders
0.000 0.976 0.023
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.977 0.023
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.023 0.977 0.000
I15.8 Other secondary hypertension
0.000 0.978 0.022
I15.2 Hypertension secondary to endocrine disorders
0.000 0.978 0.022
K91.9 Postprocedural disorder of digestive system, unspecified
0.006 0.978 0.016
K91.5 Postcholecystectomy syndrome
0.007 0.978 0.016

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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