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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130955
log Bayes Factor = 179.933
Chromosome 6   position 31,054,511  (GRCh37) Explore rs3130955 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
D80-D89 Certain disorders involving the immune mechanism
1.000 0.000 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
E05.9 Thyrotoxicosis, unspecified
0.999 0.001 0.000
L40-L45 Papulosquamous disorders
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.999 0.001 0.000
K72 Hepatic failure, not elsewhere classified
0.999 0.001 0.000
E10.1 With ketoacidosis
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
D86 Sarcoidosis
0.999 0.001 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.999 0.001 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.997 0.003 0.000
L40.0 Psoriasis vulgaris
0.997 0.003 0.000
M07.3 Other psoriatic arthropathies
0.997 0.003 0.000
E11 Non-insulin-dependent diabetes mellitus
0.993 0.007 0.000
K72.9 Hepatic failure, unspecified
0.989 0.011 0.000
E14 Unspecified diabetes mellitus
0.988 0.012 0.000
K75 Other inflammatory liver diseases
0.983 0.017 0.000
K31.8 Other specified diseases of stomach and duodenum
0.983 0.017 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.981 0.019 0.000
Q60-Q64 Congenital malformations of the urinary system
0.972 0.028 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.972 0.028 0.000
D86.9 Sarcoidosis, unspecified
0.971 0.029 0.000
D70 Agranulocytosis
0.968 0.032 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.967 0.033 0.000
K72.0 Acute and subacute hepatic failure
0.965 0.035 0.000
D86.0 Sarcoidosis of lung
0.964 0.036 0.000
E10.2 With renal complications
0.960 0.040 0.000
K75.4 Autoimmune hepatitis
0.959 0.041 0.000
E14.3 With ophthalmic complications
0.953 0.047 0.000
E10.4 With neurological complications
0.952 0.048 0.000
E11.1 With ketoacidosis
0.952 0.048 0.000
Q61 Cystic kidney disease
0.950 0.050 0.000
E10.8 With unspecified complications
0.940 0.060 0.000
E50-E64 Other nutritional deficiencies
0.936 0.064 0.000
K75.8 Other specified inflammatory liver diseases
0.929 0.071 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.928 0.072 0.000
L10-L14 Bullous disorders
0.921 0.079 0.000
E55 Vitamin D deficiency
0.914 0.086 0.000
K73 Chronic hepatitis, not elsewhere classified
0.912 0.088 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.909 0.091 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.906 0.094 0.000
Q61.3 Polycystic kidney, unspecified
0.904 0.096 0.000
E55.9 Vitamin D deficiency, unspecified
0.899 0.101 0.000
E13 Other specified diabetes mellitus
0.892 0.108 0.000
E11.3 With ophthalmic complications
0.886 0.114 0.000
L13 Other bullous disorders
0.886 0.114 0.000
Q74 Other congenital malformations of limb(s)
0.880 0.119 0.000
J45.9 Asthma, unspecified
0.877 0.123 0.000
L50-L54 Urticaria and erythema
0.877 0.123 0.000
Q65 Congenital deformities of hip
0.875 0.125 0.000
E14.2 Withrenal complications
0.873 0.127 0.000
D86.1 Sarcoidosis of lymph nodes
0.871 0.129 0.000
E11.5 With peripheral circulatory complications
0.870 0.130 0.000
D80 Immunodeficiency with predominantly antibody defects
0.869 0.131 0.000
Q61.2 Polycystic kidney, adult type
0.864 0.136 0.000
D83 Common variable immunodeficiency
0.864 0.136 0.000
L13.0 Dermatitis herpetiformis
0.861 0.139 0.000
E14.8 With unspecified complications
0.854 0.145 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.854 0.146 0.000
D86.3 Sarcoidosis of skin
0.851 0.149 0.000
L53 Other erythematous conditions
0.848 0.152 0.000
E11.6 With other specified complications
0.847 0.152 0.000
R31 Unspecified haematuria
0.000 0.162 0.838
K50-K52 Noninfective enteritis and colitis
0.837 0.162 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.837 0.163 0.000
K74 Fibrosis and cirrhosis of liver
0.829 0.171 0.000
L40.1 Generalised pustular psoriasis
0.827 0.173 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.827 0.173 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.826 0.174 0.000
K52 Other non-infective gastro-enteritis and colitis
0.826 0.174 0.000
L53.9 Erythematous condition, unspecified
0.820 0.180 0.000
E13.9 Without complications
0.820 0.180 0.000
E10.7 With multiple complications
0.820 0.180 0.000
K72.1 Chronic hepatic failure
0.819 0.181 0.000
Q76 Congenital malformations of spine and bony thorax
0.818 0.182 0.000
D50-D53 Nutritional anaemias
0.818 0.182 0.000
K90.9 Intestinal malabsorption, unspecified
0.814 0.186 0.000
D62 Acute posthaemorrhagic anaemia
0.814 0.186 0.000
Q00-Q07 Congenital malformations of the nervous system
0.811 0.189 0.000
E40-E46 Malnutrition
0.810 0.190 0.000
M07.38 Other psoriatic arthropathies (Other)
0.809 0.191 0.000
E14.1 With ketoacidosis
0.809 0.191 0.000
Chapter I Certain infectious and parasitic diseases
0.807 0.193 0.000
E11.4 With neurological complications
0.806 0.194 0.000
E11.7 With multiple complications
0.803 0.197 0.000
L40.4 Guttate psoriasis
0.802 0.198 0.000
Q65.8 Other congenital deformities of hip
0.800 0.200 0.000
K91.3 Postoperative intestinal obstruction
0.799 0.201 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.799 0.201 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.793 0.207 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.792 0.208 0.000
L44 Other papulosquamous disorders
0.789 0.211 0.000
D64.3 Other sideroblastic anaemias
0.785 0.214 0.000
Q50-Q56 Congenital malformations of genital organs
0.785 0.215 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.785 0.215 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.783 0.217 0.000
D61 Other aplastic anaemias
0.781 0.219 0.000
E16.1 Other hypoglycaemia
0.781 0.219 0.000
D86.8 Sarcoidosis of other and combined sites
0.780 0.220 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.776 0.224 0.000
B15-B19 Viral hepatitis
0.775 0.225 0.000
E11.2 With renal complications
0.773 0.227 0.000
Q35-Q37 Cleft lip and cleft palate
0.773 0.227 0.000
K90.8 Other intestinal malabsorption
0.772 0.227 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.772 0.228 0.000
K71 Toxic liver disease
0.770 0.230 0.000
Q75 Other congenital malformations of skull and face bones
0.769 0.231 0.000
Q78 Other osteochondrodysplasias
0.768 0.232 0.000
D83.9 Common variable immunodeficiency, unspecified
0.766 0.234 0.000
K77 Liver disorders in diseases classified elsewhere
0.765 0.235 0.000
E10.0 With coma
0.764 0.236 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.759 0.241 0.000
L40.3 Pustulosis palmaris et plantaris
0.754 0.246 0.000
E10.6 With other specified complications
0.752 0.248 0.000
L43 Lichen planus
0.748 0.252 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.745 0.255 0.000
D55-D59 Haemolytic anaemias
0.744 0.256 0.000
A15-A19 Tuberculosis
0.744 0.256 0.000
Q43 Other congenital malformations of intestine
0.743 0.256 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.738 0.262 0.000
K74.0 Hepatic fibrosis
0.734 0.266 0.000
Q74.1 Congenital malformation of knee
0.733 0.267 0.000
J45 Asthma
0.731 0.269 0.000
B17 Other acute viral hepatitis
0.730 0.270 0.000
E51 Thiamine deficiency
0.728 0.272 0.000
K73.9 Chronic hepatitis, unspecified
0.723 0.277 0.000
E14.6 With other specified complications
0.722 0.278 0.000
E11.0 With coma
0.722 0.278 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.720 0.280 0.000
K76 Other diseases of liver
0.720 0.280 0.000
E14.5 With peripheral circulatory complications
0.720 0.280 0.000
D64.8 Other specified anaemias
0.719 0.281 0.000
Q44.6 Cystic disease of liver
0.718 0.282 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
D81 Combined immunodeficiencies
0.717 0.283 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.717 0.283 0.000
L41 Parapsoriasis
0.716 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.716 0.283 0.000
Q61.0 Congenital single renal cyst
0.716 0.284 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.716 0.284 0.000
E00 Congenital iodine-deficiency syndrome
0.716 0.284 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.715 0.285 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.715 0.285 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.713 0.287 0.000
Q44.4 Choledochal cyst
0.711 0.288 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.711 0.288 0.000
D82 Immunodeficiency associated with other major defects
0.711 0.289 0.000
L42 Pityriasis rosea
0.710 0.289 0.000
Q44.5 Other congenital malformations of bile ducts
0.710 0.290 0.000
B18 Chronic viral hepatitis
0.709 0.291 0.000
E14.7 With multiple complications
0.708 0.292 0.000
E14.0 With coma
0.708 0.292 0.000
E14.4 With neurological complications
0.708 0.292 0.000
K74.6 Other and unspecified cirrhosis of liver
0.706 0.294 0.000
K75.2 Nonspecific reactive hepatitis
0.705 0.295 0.000
K75.1 Phlebitis of portal vein
0.705 0.295 0.000
Q73 Reduction defects of unspecified limb
0.704 0.296 0.000
Q72 Reduction defects of lower limb
0.704 0.296 0.000
Q71 Reduction defects of upper limb
0.704 0.296 0.000
Q70 Syndactyly
0.704 0.296 0.000
Q69 Polydactyly
0.704 0.296 0.000
D53 Other nutritional anaemias
0.703 0.297 0.000
K91.1 Postgastric surgery syndromes
0.702 0.298 0.000
D51 Vitamin B12 deficiency anaemia
0.701 0.299 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.699 0.301 0.000
Q76.0 Spina bifida occulta
0.698 0.302 0.000
L53.0 Toxic erythema
0.697 0.303 0.000
D74 Methaemoglobinaemia
0.697 0.303 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.697 0.303 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.697 0.303 0.000
B35-B49 Mycoses
0.697 0.303 0.000
J40-J47 Chronic lower respiratory diseases
0.689 0.311 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.688 0.312 0.000
Q03 Congenital hydrocephalus
0.688 0.312 0.000
B17.1 Acute hepatitis C
0.686 0.314 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.685 0.315 0.000
Chapter X Diseases of the respiratory system
0.685 0.315 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.684 0.316 0.000
Q04 Other congenital malformations of brain
0.684 0.316 0.000
Q64 Other congenital malformations of urinary system
0.683 0.317 0.000
Q61.8 Other cystic kidney diseases
0.681 0.318 0.000
Q61.4 Renal dysplasia
0.681 0.318 0.000
Q61.1 Polycystic kidney, infantile type
0.681 0.318 0.000
L40.8 Other psoriasis
0.680 0.320 0.000
D84 Other immunodeficiencies
0.679 0.320 0.000
D59 Acquired haemolytic anaemia
0.677 0.323 0.000
L20-L30 Dermatitis and eczema
0.674 0.326 0.000
E46 Unspecified protein-energy malnutrition
0.673 0.327 0.000
A80-A89 Viral infections of the central nervous system
0.673 0.327 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.672 0.328 0.000
Q44.7 Other congenital malformations of liver
0.672 0.328 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.671 0.329 0.000
E63 Other nutritional deficiencies
0.671 0.329 0.000
E56 Other vitamin deficiencies
0.671 0.329 0.000
E50 Vitamin A deficiency
0.671 0.329 0.000
E60 Dietary zinc deficiency
0.671 0.329 0.000
E59 Dietary selenium deficiency
0.671 0.329 0.000
E54 Ascorbic acid deficiency
0.671 0.329 0.000
E52 Niacin deficiency [pellagra]
0.671 0.329 0.000
J92.9 Pleural plaque without asbestos
0.670 0.330 0.000
L52 Erythema nodosum
0.669 0.331 0.000
L11 Other acantholytic disorders
0.669 0.331 0.000
Q68 Other congenital musculoskeletal deformities
0.669 0.331 0.000
E11.8 With unspecified complications
0.668 0.331 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.668 0.332 0.000
J92 Pleural plaque
0.667 0.333 0.000
E58 Dietary calcium deficiency
0.666 0.334 0.000
L28 Lichen simplex chronicus and prurigo
0.666 0.334 0.000
J46 Status asthmaticus
0.666 0.334 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.665 0.335 0.000
J90-J94 Other diseases of pleura
0.665 0.335 0.000
Q61.5 Medullary cystic kidney
0.663 0.337 0.000
E06 Thyroiditis
0.661 0.339 0.000
L14 Bullous disorders in diseases classified elsewhere
0.660 0.340 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.657 0.343 0.000
E55.0 Rickets, active
0.655 0.344 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.653 0.346 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.653 0.346 0.000
L10 Pemphigus
0.653 0.347 0.000
Q67.5 Congenital deformity of spine
0.650 0.350 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.649 0.351 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.649 0.351 0.000
B37 Candidiasis
0.648 0.352 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.648 0.352 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.648 0.352 0.000
Q61.9 Cystic kidney disease, unspecified
0.645 0.355 0.000
Q40 Other congenital malformations of upper alimentary tract
0.645 0.355 0.000
B37.9 Candidiasis, unspecified
0.643 0.357 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.641 0.359 0.000
E13.8 With unspecified complications
0.640 0.360 0.000
E13.7 With multiple complications
0.640 0.360 0.000
E13.6 With other specified complications
0.640 0.360 0.000
E13.5 With peripheral circulatory complications
0.640 0.360 0.000
E13.4 With neurological complications
0.640 0.360 0.000
E13.2 With renal complications
0.640 0.360 0.000
E13.1 With ketoacidosis
0.640 0.360 0.000
E13.0 With coma
0.640 0.360 0.000
L44.0 Pityriasis rubra pilaris
0.638 0.362 0.000
Q79.6 Ehlers-Danlos syndrome
0.637 0.363 0.000
L13.9 Bullous disorder, unspecified
0.635 0.365 0.000
L13.8 Other specified bullous disorders
0.635 0.365 0.000
L13.1 Subcorneal pustular dermatitis
0.635 0.365 0.000
L28.0 Lichen simplex chronicus
0.635 0.365 0.000
M07 Psoriatic and enteropathic arthropathies
0.634 0.366 0.000
Q74.9 Unspecified congenital malformation of limb(s)
0.631 0.369 0.000
Q74.8 Other specified congenital malformations of limb(s)
0.631 0.369 0.000
Q74.3 Arthrogryposis multiplex congenita
0.631 0.369 0.000
D61.9 Aplastic anaemia, unspecified
0.631 0.369 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.631 0.369 0.000
E20-E35 Disorders of other endocrine glands
0.630 0.370 0.000
L54 Erythema in diseases classified elsewhere
0.629 0.371 0.000
Q65.9 Congenital deformity of hip, unspecified
0.628 0.372 0.000
Q65.6 Unstable hip
0.628 0.372 0.000
Q65.5 Congenital subluxation of hip, unspecified
0.628 0.372 0.000
Q65.4 Congenital subluxation of hip, bilateral
0.628 0.372 0.000
Q65.3 Congenital subluxation of hip, unilateral
0.628 0.372 0.000
Q65.2 Congenital dislocation of hip, unspecified
0.628 0.372 0.000
Q65.1 Congenital dislocation of hip, bilateral
0.628 0.372 0.000
Q65.0 Congenital dislocation of hip, unilateral
0.628 0.372 0.000
Q60.0 Renal agenesis, unilateral
0.626 0.373 0.000
A20-A28 Certain zoonotic bacterial diseases
0.626 0.373 0.000
E10.5 With peripheral circulatory complications
0.626 0.374 0.000
E13.3 With ophthalmic complications
0.624 0.376 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.623 0.377 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.623 0.377 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.623 0.377 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.623 0.377 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.623 0.377 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.622 0.378 0.000
Q60.2 Renal agenesis, unspecified
0.621 0.379 0.000
D83.8 Other common variable immunodeficiencies
0.619 0.381 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.619 0.381 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.619 0.381 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.619 0.381 0.000
Q45 Other congenital malformations of digestive system
0.619 0.381 0.000
Q51 Congenital malformations of uterus and cervix
0.617 0.383 0.000
K91.5 Postcholecystectomy syndrome
0.617 0.383 0.000
Q75.4 Mandibulofacial dysostosis
0.616 0.384 0.000
Q79.8 Other congenital malformations of musculoskeletal system
0.616 0.384 0.000
B18.2 Chronic viral hepatitis C
0.616 0.384 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.616 0.384 0.000
Chapter XXII Codes for special purposes
0.615 0.385 0.000
Q78.0 Osteogenesis imperfecta
0.615 0.385 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.613 0.387 0.000
Q44.2 Atresia of bile ducts
0.613 0.387 0.000
Q44.1 Other congenital malformations of gallbladder
0.613 0.387 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.613 0.387 0.000
E05.8 Other thyrotoxicosis
0.612 0.388 0.000
L28.1 Prurigo nodularis
0.610 0.390 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.608 0.392 0.000
L53.3 Other chronic figurate erythema
0.608 0.392 0.000
L53.2 Erythema marginatum
0.608 0.392 0.000
L53.1 Erythema annulare centrifugum
0.608 0.392 0.000
D53.9 Nutritional anaemia, unspecified
0.606 0.394 0.000
K71.0 Toxic liver disease with cholestasis
0.605 0.395 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.604 0.395 0.000
Q03.0 Malformations of aqueduct of Sylvius
0.599 0.401 0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.599 0.401 0.000
K77.8 Liver disorders in other diseases classified elsewhere
0.597 0.403 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.597 0.403 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.597 0.403 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.596 0.404 0.000
E24 Cushing's syndrome
0.596 0.404 0.000
B91 Sequelae of poliomyelitis
0.596 0.404 0.000
Q37 Cleft palate with cleft lip
0.596 0.404 0.000
K74.4 Secondary biliary cirrhosis
0.594 0.406 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.594 0.406 0.000
K74.1 Hepatic sclerosis
0.594 0.406 0.000
Q76.1 Klippel-Feil syndrome
0.594 0.406 0.000
Q76.5 Cervical rib
0.588 0.412 0.000
A17 Tuberculosis of nervous system
0.588 0.412 0.000
K71.9 Toxic liver disease, unspecified
0.586 0.414 0.000
Q76.9 Congenital malformation of bony thorax, unspecified
0.586 0.414 0.000
Q76.8 Other congenital malformations of bony thorax
0.586 0.414 0.000
Q76.7 Congenital malformation of sternum
0.586 0.414 0.000
Q76.6 Other congenital malformations of ribs
0.586 0.414 0.000
Q76.3 Congenital scoliosis due to congenital bony malformation
0.586 0.414 0.000
Q76.2 Congenital spondylolisthesis
0.586 0.414 0.000
Q55 Other congenital malformations of male genital organs
0.586 0.414 0.000
Q43.0 Meckel's diverticulum
0.586 0.414 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.586 0.414 0.000
D61.1 Drug-induced aplastic anaemia
0.585 0.415 0.000
D75 Other diseases of blood and blood-forming organs
0.585 0.415 0.000
Q43.3 Congenital malformations of intestinal fixation
0.584 0.416 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.583 0.417 0.000
Q53 Undescended testicle
0.583 0.417 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.583 0.417 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.582 0.418 0.000
J45.1 Nonallergic asthma
0.582 0.418 0.000
Q06 Other congenital malformations of spinal cord
0.581 0.419 0.000
Q01 Encephalocele
0.581 0.419 0.000
Q00 Anencephaly and similar malformations
0.581 0.419 0.000
Q02 Microcephaly
0.581 0.419 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.581 0.419 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.581 0.419 0.000
E45 Retarded development following protein-energy malnutrition
0.581 0.419 0.000
E43 Unspecified severe protein-energy malnutrition
0.581 0.419 0.000
E42 Marasmic kwashiorkor
0.581 0.419 0.000
E41 Nutritional marasmus
0.581 0.419 0.000
E40 Kwashiorkor
0.581 0.419 0.000
D59.1 Other autoimmune haemolytic anaemias
0.580 0.420 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.578 0.421 0.000
A75-A79 Rickettsioses
0.578 0.421 0.000
A70-A74 Other diseases caused by chlamydiae
0.578 0.421 0.000
E51.2 Wernicke's encephalopathy
0.578 0.422 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.578 0.422 0.000
Q39 Congenital malformations of oesophagus
0.576 0.424 0.000
K76.7 Hepatorenal syndrome
0.576 0.424 0.000
B16 Acute hepatitis B
0.575 0.425 0.000
Q35 Cleft palate
0.574 0.426 0.000
A65-A69 Other spirochaetal diseases
0.574 0.426 0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified
0.573 0.427 0.000
Q79.5 Other congenital malformations of abdominal wall
0.573 0.427 0.000
Q79.4 Prune belly syndrome
0.573 0.427 0.000
Q79.3 Gastroschisis
0.573 0.427 0.000
Q79.2 Exomphalos
0.573 0.427 0.000
Q79.1 Other congenital malformations of diaphragm
0.573 0.427 0.000
Q79.0 Congenital diaphragmatic hernia
0.573 0.427 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.572 0.428 0.000
Q62.5 Duplication of ureter
0.572 0.428 0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
0.572 0.428 0.000
Q60.6 Potter's syndrome
0.569 0.431 0.000
Q60.5 Renal hypoplasia, unspecified
0.569 0.431 0.000
Q60.4 Renal hypoplasia, bilateral
0.569 0.431 0.000
Q60.3 Renal hypoplasia, unilateral
0.569 0.431 0.000
Q60.1 Renal agenesis, bilateral
0.569 0.431 0.000
Q04.8 Other specified congenital malformations of brain
0.569 0.431 0.000
E61 Deficiency of other nutrient elements
0.568 0.432 0.000
L53.8 Other specified erythematous conditions
0.568 0.432 0.000
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation
0.567 0.433 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.566 0.434 0.000
Q63 Other congenital malformations of kidney
0.566 0.434 0.000
L44.9 Papulosquamous disorder, unspecified
0.565 0.434 0.000
L44.8 Other specified papulosquamous disorders
0.565 0.434 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.565 0.434 0.000
L44.3 Lichen ruber moniliformis
0.565 0.434 0.000
L44.2 Lichen striatus
0.565 0.434 0.000
L44.1 Lichen nitidus
0.565 0.434 0.000
B17.2 Acute hepatitis E
0.565 0.435 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.565 0.435 0.000
K75.9 Inflammatory liver disease, unspecified
0.565 0.435 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.564 0.436 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.563 0.437 0.000
K76.3 Infarction of liver
0.563 0.437 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.563 0.437 0.000
Q67.8 Other congenital deformities of chest
0.563 0.437 0.000
Q67.7 Pectus carinatum
0.563 0.437 0.000
Q67.3 Plagiocephaly
0.563 0.437 0.000
Q67.2 Dolichocephaly
0.563 0.437 0.000
Q67.1 Compression facies
0.563 0.437 0.000
Q67.0 Facial asymmetry
0.563 0.437 0.000
B44 Aspergillosis
0.563 0.437 0.000
L43.9 Lichen planus, unspecified
0.562 0.438 0.000
Q67.4 Other congenital deformities of skull, face and jaw
0.562 0.438 0.000
K76.9 Liver disease, unspecified
0.562 0.438 0.000
A86 Unspecified viral encephalitis
0.562 0.438 0.000
D61.8 Other specified aplastic anaemias
0.560 0.440 0.000
D61.3 Idiopathic aplastic anaemia
0.560 0.440 0.000
D61.2 Aplastic anaemia due to other external agents
0.560 0.440 0.000
K76.6 Portal hypertension
0.560 0.440 0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed
0.559 0.441 0.000
D60.8 Other acquired pure red cell aplasias
0.556 0.443 0.000
D60.1 Transient acquired pure red cell aplasia
0.556 0.443 0.000
D60.0 Chronic acquired pure red cell aplasia
0.556 0.443 0.000
Q54 Hypospadias
0.555 0.445 0.000
Q67.6 Pectus excavatum
0.554 0.445 0.000
Q36 Cleft lip
0.554 0.446 0.000
K71.8 Toxic liver disease with other disorders of liver
0.552 0.447 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.552 0.447 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.552 0.447 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.552 0.447 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.552 0.447 0.000
K71.2 Toxic liver disease with acute hepatitis
0.552 0.447 0.000
Q75.9 Congenital malformation of skull and face bones, unspecified
0.551 0.449 0.000
Q75.8 Other specified congenital malformations of skull and face bones
0.551 0.449 0.000
Q75.5 Oculomandibular dysostosis
0.551 0.449 0.000
Q75.3 Macrocephaly
0.551 0.449 0.000
Q75.2 Hypertelorism
0.551 0.449 0.000
Q75.1 Craniofacial dysostosis
0.551 0.449 0.000
Q75.0 Craniosynostosis
0.551 0.449 0.000
A18 Tuberculosis of other organs
0.551 0.449 0.000
P10-P15 Birth trauma
0.551 0.449 0.000
Q78.9 Osteochondrodysplasia, unspecified
0.550 0.449 0.000
Q78.8 Other specified osteochondrodysplasias
0.550 0.449 0.000
Q78.6 Multiple congenital exostoses
0.550 0.449 0.000
Q78.5 Metaphyseal dysplasia
0.550 0.449 0.000
Q78.4 Enchondromatosis
0.550 0.449 0.000
Q78.3 Progressive diaphyseal dysplasia
0.550 0.449 0.000
Q78.2 Osteopetrosis
0.550 0.449 0.000
Q78.1 Polyostotic fibrous dysplasia
0.550 0.449 0.000
B19 Unspecified viral hepatitis
0.550 0.450 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.549 0.451 0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.549 0.451 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.547 0.453 0.000
D84.8 Other specified immunodeficiencies
0.547 0.453 0.000
Q62.1 Atresia and stenosis of ureter
0.547 0.453 0.000
D72 Other disorders of white blood cells
0.546 0.454 0.000
Q52 Other congenital malformations of female genitalia
0.543 0.457 0.000
L43.8 Other lichen planus
0.543 0.457 0.000
B17.9 Acute viral hepatitis, unspecified
0.539 0.461 0.000
L43.3 Subacute (active) lichen planus
0.536 0.464 0.000
L43.2 Lichenoid drug reaction
0.536 0.464 0.000
L43.1 Bullous lichen planus
0.536 0.464 0.000
L43.0 Hypertrophic lichen planus
0.536 0.464 0.000
L25 Unspecified contact dermatitis
0.536 0.464 0.000
K76.1 Chronic passive congestion of liver
0.535 0.465 0.000
Q62.8 Other congenital malformations of ureter
0.534 0.466 0.000
Q62.7 Congenital vesico-uretero-renal reflux
0.534 0.466 0.000
Q62.6 Malposition of ureter
0.534 0.466 0.000
Q62.4 Agenesis of ureter
0.534 0.466 0.000
Q62.3 Other obstructive defects of renal pelvis and ureter
0.534 0.466 0.000
Q62.2 Congenital megaloureter
0.534 0.466 0.000
Q62.0 Congenital hydronephrosis
0.534 0.466 0.000
D55 Anaemia due to enzyme disorders
0.534 0.466 0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.534 0.466 0.000
Q77.4 Achondroplasia
0.533 0.466 0.000
A19 Miliary tuberculosis
0.533 0.467 0.000
Q43.7 Persistent cloaca
0.533 0.467 0.000
Q43.6 Congenital fistula of rectum and anus
0.533 0.467 0.000
Q43.5 Ectopic anus
0.533 0.467 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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