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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132564
log Bayes Factor = 137.365
Chromosome 6   position 31,047,620  (GRCh37) Explore rs3132564 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
K72 Hepatic failure, not elsewhere classified
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.998 0.002 0.000
K72.9 Hepatic failure, unspecified
0.997 0.003 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.996 0.004 0.000
K51 Ulcerative colitis
0.000 0.004 0.996
K90 Intestinal malabsorption
0.995 0.005 0.000
E14 Unspecified diabetes mellitus
0.994 0.006 0.000
M07.3 Other psoriatic arthropathies
0.991 0.009 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.990 0.010 0.000
K51.4 Pseudopolyposis of colon
0.000 0.010 0.990
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.987 0.013 0.000
L40.0 Psoriasis vulgaris
0.987 0.013 0.000
# Top node
0.986 0.014 0.000
L40-L45 Papulosquamous disorders
0.986 0.014 0.000
Chapter XI Diseases of the digestive system
0.985 0.015 0.000
K90-K93 Other diseases of the digestive system
0.985 0.015 0.000
D80-D89 Certain disorders involving the immune mechanism
0.984 0.016 0.000
D86 Sarcoidosis
0.982 0.018 0.000
E11.9 Without complications
0.980 0.020 0.000
K75 Other inflammatory liver diseases
0.975 0.025 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.974 0.026 0.000
E14.3 With ophthalmic complications
0.973 0.027 0.000
M07 Psoriatic and enteropathic arthropathies
0.970 0.030 0.000
K76 Other diseases of liver
0.966 0.034 0.000
D60-D64 Aplastic and other anaemias
0.962 0.038 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.961 0.039 0.000
D86.9 Sarcoidosis, unspecified
0.959 0.041 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.959 0.041 0.000
E11.1 With ketoacidosis
0.958 0.042 0.000
M05-M14 Inflammatory polyarthropathies
0.957 0.043 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.949 0.051 0.000
E10.8 With unspecified complications
0.947 0.053 0.000
D64 Other anaemias
0.944 0.056 0.000
K73 Chronic hepatitis, not elsewhere classified
0.939 0.061 0.000
D64.9 Anaemia, unspecified
0.935 0.065 0.000
E11.3 With ophthalmic complications
0.932 0.068 0.000
K75.4 Autoimmune hepatitis
0.931 0.069 0.000
M05 Seropositive rheumatoid arthritis
0.924 0.076 0.000
K75.8 Other specified inflammatory liver diseases
0.917 0.083 0.000
D86.0 Sarcoidosis of lung
0.915 0.085 0.000
K74 Fibrosis and cirrhosis of liver
0.915 0.085 0.000
M06 Other rheumatoid arthritis
0.913 0.087 0.000
K72.0 Acute and subacute hepatic failure
0.906 0.094 0.000
K76.6 Portal hypertension
0.905 0.095 0.000
K76.8 Other specified diseases of liver
0.905 0.095 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.904 0.096 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.102 0.898
K74.6 Other and unspecified cirrhosis of liver
0.893 0.107 0.000
E11.4 With neurological complications
0.890 0.110 0.000
E11.5 With peripheral circulatory complications
0.888 0.112 0.000
K51.8 Other ulcerative colitis
0.000 0.112 0.888
Q38-Q45 Other congenital malformations of the digestive system
0.887 0.113 0.000
D86.1 Sarcoidosis of lymph nodes
0.886 0.114 0.000
M06.9 Rheumatoid arthritis, unspecified
0.885 0.115 0.000
L10-L14 Bullous disorders
0.881 0.119 0.000
E10.2 With renal complications
0.880 0.120 0.000
K73.9 Chronic hepatitis, unspecified
0.880 0.120 0.000
L40.4 Guttate psoriasis
0.870 0.130 0.000
D80 Immunodeficiency with predominantly antibody defects
0.869 0.131 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.868 0.132 0.000
Chapter I Certain infectious and parasitic diseases
0.857 0.143 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.854 0.146 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.844 0.156 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.843 0.157 0.000
Q78 Other osteochondrodysplasias
0.842 0.158 0.000
E10.6 With other specified complications
0.839 0.160 0.000
K71 Toxic liver disease
0.838 0.162 0.000
B15-B19 Viral hepatitis
0.835 0.165 0.000
E50-E64 Other nutritional deficiencies
0.832 0.168 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.830 0.170 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.830 0.170 0.000
L13 Other bullous disorders
0.829 0.171 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.829 0.171 0.000
E14.9 Without complications
0.829 0.171 0.000
E10.7 With multiple complications
0.828 0.172 0.000
E14.2 Withrenal complications
0.827 0.173 0.000
E13 Other specified diabetes mellitus
0.827 0.173 0.000
K51.5 Mucosal proctocolitis
0.000 0.176 0.824
K76.7 Hepatorenal syndrome
0.823 0.177 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.821 0.179 0.000
K90.9 Intestinal malabsorption, unspecified
0.821 0.179 0.000
E10.0 With coma
0.820 0.180 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.180 0.820
D70 Agranulocytosis
0.818 0.182 0.000
Q65 Congenital deformities of hip
0.817 0.183 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.185 0.815
Q74 Other congenital malformations of limb(s)
0.814 0.186 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.810 0.190 0.000
A80-A89 Viral infections of the central nervous system
0.808 0.192 0.000
E14.1 With ketoacidosis
0.808 0.192 0.000
B17 Other acute viral hepatitis
0.806 0.194 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.805 0.195 0.000
D83 Common variable immunodeficiency
0.800 0.200 0.000
D86.8 Sarcoidosis of other and combined sites
0.799 0.201 0.000
E16.1 Other hypoglycaemia
0.796 0.204 0.000
L41 Parapsoriasis
0.794 0.206 0.000
E10.5 With peripheral circulatory complications
0.794 0.206 0.000
E10.4 With neurological complications
0.793 0.207 0.000
L13.0 Dermatitis herpetiformis
0.793 0.207 0.000
D62 Acute posthaemorrhagic anaemia
0.792 0.208 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.789 0.211 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.788 0.212 0.000
L40.1 Generalised pustular psoriasis
0.786 0.214 0.000
B17.1 Acute hepatitis C
0.784 0.216 0.000
E14.8 With unspecified complications
0.784 0.216 0.000
K72.1 Chronic hepatic failure
0.784 0.216 0.000
E20-E35 Disorders of other endocrine glands
0.783 0.217 0.000
Chapter IX Diseases of the circulatory system
0.779 0.221 0.000
E11.7 With multiple complications
0.779 0.221 0.000
M06.4 Inflammatory polyarthropathy
0.779 0.221 0.000
A15-A19 Tuberculosis
0.778 0.222 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.775 0.225 0.000
E55 Vitamin D deficiency
0.773 0.227 0.000
M07.38 Other psoriatic arthropathies (Other)
0.772 0.228 0.000
B18 Chronic viral hepatitis
0.771 0.229 0.000
K75.9 Inflammatory liver disease, unspecified
0.769 0.231 0.000
Q78.0 Osteogenesis imperfecta
0.766 0.234 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.766 0.234 0.000
M06.3 Rheumatoid nodule
0.765 0.235 0.000
Q43 Other congenital malformations of intestine
0.764 0.236 0.000
Q00-Q07 Congenital malformations of the nervous system
0.764 0.236 0.000
K77 Liver disorders in diseases classified elsewhere
0.763 0.237 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.761 0.239 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.760 0.240 0.000
I85.9 Oesophageal varices without bleeding
0.754 0.246 0.000
L44 Other papulosquamous disorders
0.753 0.247 0.000
I85 Oesophageal varices
0.753 0.247 0.000
K76.3 Infarction of liver
0.752 0.248 0.000
A86 Unspecified viral encephalitis
0.751 0.249 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.750 0.250 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.750 0.250 0.000
E40-E46 Malnutrition
0.748 0.252 0.000
E14.0 With coma
0.747 0.253 0.000
Q76 Congenital malformations of spine and bony thorax
0.742 0.258 0.000
Q60-Q64 Congenital malformations of the urinary system
0.738 0.262 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.738 0.262 0.000
E11.8 With unspecified complications
0.736 0.264 0.000
B50-B64 Protozoal diseases
0.736 0.264 0.000
E11.6 With other specified complications
0.736 0.264 0.000
M08 Juvenile arthritis
0.735 0.265 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.735 0.265 0.000
Q44.6 Cystic disease of liver
0.731 0.269 0.000
E55.9 Vitamin D deficiency, unspecified
0.731 0.269 0.000
E13.9 Without complications
0.729 0.271 0.000
Q68 Other congenital musculoskeletal deformities
0.728 0.272 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.726 0.274 0.000
Q50-Q56 Congenital malformations of genital organs
0.726 0.274 0.000
Q79.8 Other congenital malformations of musculoskeletal system
0.726 0.274 0.000
M12 Other specific arthropathies
0.726 0.274 0.000
I81 Portal vein thrombosis
0.724 0.276 0.000
E27 Other disorders of adrenal gland
0.723 0.277 0.000
Q65.8 Other congenital deformities of hip
0.722 0.278 0.000
D55-D59 Haemolytic anaemias
0.722 0.278 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.716 0.284 0.000
E00 Congenital iodine-deficiency syndrome
0.716 0.284 0.000
B18.2 Chronic viral hepatitis C
0.716 0.284 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.713 0.286 0.000
K90.3 Pancreatic steatorrhoea
0.713 0.287 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.713 0.287 0.000
K90.1 Tropical sprue
0.713 0.287 0.000
E14.7 With multiple complications
0.713 0.287 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.710 0.290 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.710 0.290 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.708 0.292 0.000
E14.4 With neurological complications
0.708 0.292 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.707 0.293 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.706 0.294 0.000
Q44.5 Other congenital malformations of bile ducts
0.706 0.294 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.706 0.294 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.706 0.294 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.705 0.294 0.000
D81 Combined immunodeficiencies
0.705 0.295 0.000
E27.1 Primary adrenocortical insufficiency
0.704 0.296 0.000
E14.6 With other specified complications
0.700 0.300 0.000
K75.2 Nonspecific reactive hepatitis
0.699 0.301 0.000
K75.1 Phlebitis of portal vein
0.699 0.301 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.699 0.301 0.000
M40-M43 Deforming dorsopathies
0.699 0.301 0.000
M14 Arthropathies in other diseases classified elsewhere
0.697 0.303 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.697 0.303 0.000
M07.5 Arthropathy in ulcerative colitis
0.695 0.305 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.695 0.305 0.000
M07.2 Psoriatic spondylitis
0.695 0.305 0.000
M07.1 Arthritis mutilans
0.695 0.305 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.695 0.305 0.000
D86.3 Sarcoidosis of skin
0.695 0.305 0.000
D82 Immunodeficiency associated with other major defects
0.694 0.306 0.000
K76.5 Hepatic veno-occlusive disease
0.693 0.307 0.000
K76.4 Peliosis hepatis
0.693 0.307 0.000
K76.2 Central haemorrhagic necrosis of liver
0.693 0.307 0.000
I05-I09 Chronic rheumatic heart diseases
0.693 0.307 0.000
L40.8 Other psoriasis
0.691 0.309 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.690 0.309 0.000
A20-A28 Certain zoonotic bacterial diseases
0.689 0.311 0.000
M05.8 Other seropositive rheumatoid arthritis
0.689 0.311 0.000
D61 Other aplastic anaemias
0.687 0.313 0.000
I27 Other pulmonary heart diseases
0.686 0.314 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.686 0.314 0.000
Q70 Syndactyly
0.686 0.314 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.685 0.315 0.000
E34 Other endocrine disorders
0.685 0.315 0.000
D64.0 Hereditary sideroblastic anaemia
0.684 0.316 0.000
Q35-Q37 Cleft lip and cleft palate
0.684 0.316 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.683 0.317 0.000
K76.9 Liver disease, unspecified
0.682 0.318 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.682 0.318 0.000
L42 Pityriasis rosea
0.681 0.319 0.000
Q75 Other congenital malformations of skull and face bones
0.680 0.320 0.000
Q73 Reduction defects of unspecified limb
0.680 0.320 0.000
Q72 Reduction defects of lower limb
0.680 0.320 0.000
Q71 Reduction defects of upper limb
0.680 0.320 0.000
Q69 Polydactyly
0.680 0.320 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.679 0.321 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.678 0.322 0.000
D64.4 Congenital dyserythropoietic anaemia
0.676 0.323 0.000
D64.3 Other sideroblastic anaemias
0.676 0.323 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.676 0.323 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.676 0.323 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.676 0.324 0.000
M41 Scoliosis
0.676 0.324 0.000
I07 Rheumatic tricuspid valve diseases
0.674 0.326 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.674 0.326 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.674 0.326 0.000
I86 Varicose veins of other sites
0.673 0.327 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.672 0.328 0.000
D83.9 Common variable immunodeficiency, unspecified
0.668 0.332 0.000
L40.3 Pustulosis palmaris et plantaris
0.667 0.333 0.000
E11.0 With coma
0.665 0.335 0.000
E24 Cushing's syndrome
0.664 0.336 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.662 0.338 0.000
M05.0 Felty's syndrome
0.662 0.338 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.662 0.338 0.000
I07.1 Tricuspid insufficiency
0.661 0.339 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.660 0.340 0.000
Q74.1 Congenital malformation of knee
0.660 0.340 0.000
I85.0 Oesophageal varices with bleeding
0.658 0.342 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.657 0.343 0.000
L41.1 Pityriasis lichenoides chronica
0.657 0.343 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.657 0.343 0.000
Q04 Other congenital malformations of brain
0.657 0.343 0.000
Q45 Other congenital malformations of digestive system
0.657 0.343 0.000
K74.4 Secondary biliary cirrhosis
0.656 0.344 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.656 0.344 0.000
K74.1 Hepatic sclerosis
0.656 0.344 0.000
K71.0 Toxic liver disease with cholestasis
0.656 0.344 0.000
M06.2 Rheumatoid bursitis
0.655 0.345 0.000
M06.1 Adult-onset Still's disease
0.655 0.345 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.654 0.346 0.000
A87 Viral meningitis
0.653 0.347 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.653 0.347 0.000
B59 Pneumocystosis
0.650 0.350 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.649 0.351 0.000
K90.8 Other intestinal malabsorption
0.648 0.351 0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed
0.648 0.352 0.000
K50-K52 Noninfective enteritis and colitis
0.553 0.352 0.095
I98.2 Oesophageal varices in diseases classified elsewhere
0.648 0.352 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.648 0.352 0.000
D59 Acquired haemolytic anaemia
0.647 0.353 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.646 0.354 0.000
Q44.4 Choledochal cyst
0.645 0.355 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.645 0.355 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.644 0.356 0.000
M07.6 Other enteropathic arthropathies
0.644 0.356 0.000
E14.5 With peripheral circulatory complications
0.641 0.359 0.000
Q43.3 Congenital malformations of intestinal fixation
0.640 0.360 0.000
I86.4 Gastric varices
0.639 0.361 0.000
L10 Pemphigus
0.639 0.361 0.000
B35-B49 Mycoses
0.638 0.362 0.000
A65-A69 Other spirochaetal diseases
0.638 0.362 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.637 0.363 0.000
D50-D53 Nutritional anaemias
0.637 0.363 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.636 0.364 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.636 0.364 0.000
Q79.6 Ehlers-Danlos syndrome
0.635 0.365 0.000
L43 Lichen planus
0.635 0.365 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.634 0.366 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.633 0.367 0.000
E70-E90 Metabolic disorders
0.633 0.367 0.000
Q03 Congenital hydrocephalus
0.632 0.367 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.632 0.368 0.000
L14 Bullous disorders in diseases classified elsewhere
0.631 0.368 0.000
E34.9 Endocrine disorder, unspecified
0.631 0.369 0.000
B65-B83 Helminthiases
0.631 0.369 0.000
M05.1 Rheumatoid lung disease
0.630 0.369 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.630 0.370 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.630 0.370 0.000
B17.2 Acute hepatitis E
0.630 0.370 0.000
I27.9 Pulmonary heart disease, unspecified
0.628 0.372 0.000
A17 Tuberculosis of nervous system
0.627 0.373 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.626 0.373 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.626 0.373 0.000
K74.5 Biliary cirrhosis, unspecified
0.626 0.373 0.000
I27.0 Primary pulmonary hypertension
0.623 0.377 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.623 0.377 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.623 0.377 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.623 0.377 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.623 0.377 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.623 0.377 0.000
E78.2 Mixed hyperlipidaemia
0.623 0.377 0.000
E51 Thiamine deficiency
0.621 0.379 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.621 0.379 0.000
Q40 Other congenital malformations of upper alimentary tract
0.620 0.379 0.000
K76.1 Chronic passive congestion of liver
0.620 0.380 0.000
A80 Acute poliomyelitis
0.619 0.381 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.618 0.382 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.617 0.383 0.000
Q43.0 Meckel's diverticulum
0.617 0.383 0.000
J33.0 Polyp of nasal cavity
0.616 0.384 0.000
M41.9 Scoliosis, unspecified
0.616 0.384 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.615 0.385 0.000
A75-A79 Rickettsioses
0.615 0.385 0.000
A70-A74 Other diseases caused by chlamydiae
0.615 0.385 0.000
Q76.1 Klippel-Feil syndrome
0.615 0.385 0.000
M05.2 Rheumatoid vasculitis
0.613 0.386 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.610 0.390 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.609 0.391 0.000
K71.9 Toxic liver disease, unspecified
0.607 0.393 0.000
E58 Dietary calcium deficiency
0.607 0.393 0.000
E29 Testicular dysfunction
0.606 0.394 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.605 0.395 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.605 0.395 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.605 0.395 0.000
Q76.0 Spina bifida occulta
0.604 0.395 0.000
D74 Methaemoglobinaemia
0.604 0.395 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.604 0.395 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.604 0.395 0.000
Q78.9 Osteochondrodysplasia, unspecified
0.604 0.396 0.000
Q78.8 Other specified osteochondrodysplasias
0.604 0.396 0.000
Q78.6 Multiple congenital exostoses
0.604 0.396 0.000
Q78.5 Metaphyseal dysplasia
0.604 0.396 0.000
Q78.4 Enchondromatosis
0.604 0.396 0.000
Q78.3 Progressive diaphyseal dysplasia
0.604 0.396 0.000
Q78.2 Osteopetrosis
0.604 0.396 0.000
Q78.1 Polyostotic fibrous dysplasia
0.604 0.396 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.604 0.396 0.000
E25 Adrenogenital disorders
0.601 0.399 0.000
K71.8 Toxic liver disease with other disorders of liver
0.601 0.399 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.601 0.399 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.601 0.399 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.601 0.399 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.601 0.399 0.000
K71.2 Toxic liver disease with acute hepatitis
0.601 0.399 0.000
P10-P15 Birth trauma
0.600 0.400 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.598 0.402 0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.598 0.402 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.596 0.404 0.000
E63 Other nutritional deficiencies
0.596 0.404 0.000
E50 Vitamin A deficiency
0.596 0.404 0.000
E60 Dietary zinc deficiency
0.596 0.404 0.000
E59 Dietary selenium deficiency
0.596 0.404 0.000
E52 Niacin deficiency [pellagra]
0.596 0.404 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.596 0.404 0.000
L12 Pemphigoid
0.596 0.404 0.000
A18 Tuberculosis of other organs
0.596 0.404 0.000
M11 Other crystal arthropathies
0.595 0.405 0.000
Q44.7 Other congenital malformations of liver
0.595 0.405 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.595 0.405 0.000
Q44.2 Atresia of bile ducts
0.595 0.405 0.000
Q44.1 Other congenital malformations of gallbladder
0.595 0.405 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.595 0.405 0.000
L13.9 Bullous disorder, unspecified
0.595 0.405 0.000
L13.8 Other specified bullous disorders
0.595 0.405 0.000
L13.1 Subcorneal pustular dermatitis
0.595 0.405 0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified
0.595 0.405 0.000
Q79.5 Other congenital malformations of abdominal wall
0.595 0.405 0.000
Q79.4 Prune belly syndrome
0.595 0.405 0.000
Q79.3 Gastroschisis
0.595 0.405 0.000
Q79.2 Exomphalos
0.595 0.405 0.000
Q79.1 Other congenital malformations of diaphragm
0.595 0.405 0.000
Q79.0 Congenital diaphragmatic hernia
0.595 0.405 0.000
K77.8 Liver disorders in other diseases classified elsewhere
0.593 0.407 0.000
E24.0 Pituitary-dependent Cushing's disease
0.593 0.407 0.000
E13.8 With unspecified complications
0.593 0.407 0.000
E13.7 With multiple complications
0.593 0.407 0.000
E13.6 With other specified complications
0.593 0.407 0.000
E13.5 With peripheral circulatory complications
0.593 0.407 0.000
E13.4 With neurological complications
0.593 0.407 0.000
E13.2 With renal complications
0.593 0.407 0.000
E13.1 With ketoacidosis
0.593 0.407 0.000
E13.0 With coma
0.593 0.407 0.000
Q67.5 Congenital deformity of spine
0.592 0.407 0.000
I82 Other venous embolism and thrombosis
0.592 0.408 0.000
L11 Other acantholytic disorders
0.590 0.410 0.000
Q39 Congenital malformations of oesophagus
0.590 0.410 0.000
M41.8 Other forms of scoliosis
0.590 0.410 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.588 0.411 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.588 0.412 0.000
I27.2 Other secondary pulmonary hypertension
0.587 0.413 0.000
L44.0 Pityriasis rubra pilaris
0.586 0.413 0.000
E85 Amyloidosis
0.586 0.414 0.000
Q65.9 Congenital deformity of hip, unspecified
0.586 0.414 0.000
Q65.6 Unstable hip
0.586 0.414 0.000
Q65.5 Congenital subluxation of hip, unspecified
0.586 0.414 0.000
Q65.4 Congenital subluxation of hip, bilateral
0.586 0.414 0.000
Q65.3 Congenital subluxation of hip, unilateral
0.586 0.414 0.000
Q65.2 Congenital dislocation of hip, unspecified
0.586 0.414 0.000
Q65.1 Congenital dislocation of hip, bilateral
0.586 0.414 0.000
Q65.0 Congenital dislocation of hip, unilateral
0.586 0.414 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.585 0.415 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.585 0.415 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.584 0.415 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.584 0.416 0.000
Q74.9 Unspecified congenital malformation of limb(s)
0.584 0.416 0.000
Q74.8 Other specified congenital malformations of limb(s)
0.584 0.416 0.000
Q74.3 Arthrogryposis multiplex congenita
0.584 0.416 0.000
E31 Polyglandular dysfunction
0.583 0.417 0.000
B91 Sequelae of poliomyelitis
0.580 0.420 0.000
A88 Other viral infections of central nervous system, not elsewhere classified
0.579 0.421 0.000
A85 Other viral encephalitis, not elsewhere classified
0.579 0.421 0.000
A84 Tick-borne viral encephalitis
0.579 0.421 0.000
A83 Mosquito-borne viral encephalitis
0.579 0.421 0.000
A82 Rabies
0.579 0.421 0.000
A91 Dengue haemorrhagic fever
0.579 0.421 0.000
A90 Dengue fever [classical dengue]
0.579 0.421 0.000
A89 Unspecified viral infection of central nervous system
0.579 0.421 0.000
E54 Ascorbic acid deficiency
0.579 0.421 0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier
0.578 0.422 0.000
D84 Other immunodeficiencies
0.575 0.424 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.574 0.426 0.000
D83.8 Other common variable immunodeficiencies
0.573 0.426 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.573 0.426 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.573 0.426 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.573 0.426 0.000
Q66 Congenital deformities of feet
0.573 0.426 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.573 0.427 0.000
M60-M63 Disorders of muscles
0.570 0.429 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.570 0.430 0.000
E56 Other vitamin deficiencies
0.570 0.430 0.000
L41.9 Parapsoriasis, unspecified
0.570 0.430 0.000
L41.8 Other parapsoriasis
0.570 0.430 0.000
L41.5 Retiform parapsoriasis
0.570 0.430 0.000
L41.4 Large plaque parapsoriasis
0.570 0.430 0.000
L41.3 Small plaque parapsoriasis
0.570 0.430 0.000
L41.2 Lymphomatoid papulosis
0.570 0.430 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.570 0.430 0.000
Q68.8 Other specified congenital musculoskeletal deformities
0.569 0.431 0.000
K74.0 Hepatic fibrosis
0.567 0.433 0.000
E46 Unspecified protein-energy malnutrition
0.567 0.433 0.000
E22 Hyperfunction of pituitary gland
0.564 0.436 0.000
E05.8 Other thyrotoxicosis
0.564 0.436 0.000
B16 Acute hepatitis B
0.563 0.437 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.561 0.439 0.000
E32 Diseases of thymus
0.561 0.439 0.000
E30 Disorders of puberty, not elsewhere classified
0.561 0.439 0.000
B17.9 Acute viral hepatitis, unspecified
0.561 0.439 0.000
M08.9 Juvenile arthritis, unspecified
0.561 0.439 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.560 0.440 0.000
D61.1 Drug-induced aplastic anaemia
0.558 0.442 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.558 0.442 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.558 0.442 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.558 0.442 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.558 0.442 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.558 0.442 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.558 0.442 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.558 0.442 0.000
B18.9 Chronic viral hepatitis, unspecified
0.558 0.442 0.000
A19 Miliary tuberculosis
0.558 0.442 0.000
A28 Other zoonotic bacterial diseases, not elsewhere classified
0.556 0.444 0.000
E55.0 Rickets, active
0.554 0.446 0.000
A81 Atypical virus infections of central nervous system
0.554 0.446 0.000
E85.4 Organ-limited amyloidosis
0.554 0.446 0.000
M06.33 Rheumatoid nodule (Forearm)
0.553 0.447 0.000
M06.8 Other specified rheumatoid arthritis
0.552 0.447 0.000
D59.1 Other autoimmune haemolytic anaemias
0.553 0.447 0.000
B18.8 Other chronic viral hepatitis
0.553 0.447 0.000
B18.0 Chronic viral hepatitis B with delta-agent
0.553 0.447 0.000
B19 Unspecified viral hepatitis
0.552 0.448 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.552 0.448 0.000
J33 Nasal polyp
0.552 0.448 0.000
A15.0 Tuberculosis of lung, confirmed by sputum microscopy with or without culture
0.552 0.448 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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