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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132940
log Bayes Factor = 160.057
Chromosome 6   position 32,161,396  (GRCh37) Explore rs3132940 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
L43 Lichen planus
0.000 0.001 0.999
M06 Other rheumatoid arthritis
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.002 0.998
L43.9 Lichen planus, unspecified
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.005 0.995
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
E14.3 With ophthalmic complications
0.000 0.006 0.994
L40.9 Psoriasis, unspecified
0.000 0.006 0.994
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.007 0.993
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.008 0.992
E70-E90 Metabolic disorders
0.000 0.009 0.991
E14.9 Without complications
0.000 0.009 0.991
G37.9 Demyelinating disease of central nervous system, unspecified
0.991 0.009 0.000
I22 Subsequent myocardial infarction
0.000 0.009 0.991
I20.9 Angina pectoris, unspecified
0.000 0.010 0.990
M05 Seropositive rheumatoid arthritis
0.000 0.011 0.989
H43-H45 Disorders of vitreous body and globe
0.000 0.012 0.988
K51.9 Ulcerative colitis, unspecified
0.986 0.014 0.000
K51 Ulcerative colitis
0.985 0.015 0.000
I20.0 Unstable angina
0.000 0.015 0.985
H40-H42 Glaucoma
0.000 0.016 0.984
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.016 0.984
H43 Disorders of vitreous body
0.000 0.016 0.984
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.017 0.983
K70-K77 Diseases of liver
0.000 0.017 0.983
J45.9 Asthma, unspecified
0.000 0.019 0.981
E11.3 With ophthalmic complications
0.000 0.021 0.979
I25.1 Atherosclerotic heart disease
0.000 0.023 0.977
H40.9 Glaucoma, unspecified
0.000 0.026 0.974
K51.3 Ulcerative (chronic) rectosigmoiditis
0.974 0.026 0.000
H40 Glaucoma
0.000 0.026 0.974
I30-I52 Other forms of heart disease
0.000 0.029 0.971
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.030 0.970
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.030 0.970
E10.5 With peripheral circulatory complications
0.000 0.030 0.970
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.032 0.968
I35 Nonrheumatic aortic valve disorders
0.000 0.036 0.964
I35.0 Aortic (valve) stenosis
0.000 0.037 0.963
K74 Fibrosis and cirrhosis of liver
0.000 0.040 0.960
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.045 0.955
I47 Paroxysmal tachycardia
0.000 0.045 0.955
H43.8 Other disorders of vitreous body
0.000 0.046 0.954
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.047 0.953
I25.2 Old myocardial infarction
0.000 0.048 0.952
K50-K52 Noninfective enteritis and colitis
0.012 0.050 0.938
I12 Hypertensive renal disease
0.000 0.054 0.946
H34 Retinal vascular occlusions
0.000 0.055 0.945
I25.5 Ischaemic cardiomyopathy
0.000 0.059 0.941
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.059 0.941
H43.3 Other vitreous opacities
0.000 0.060 0.940
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.060 0.940
K74.3 Primary biliary cirrhosis
0.000 0.060 0.940
I24 Other acute ischaemic heart diseases
0.000 0.061 0.939
I21 Acute myocardial infarction
0.000 0.062 0.938
K55-K64 Other diseases of intestines
0.000 0.067 0.933
I47.1 Supraventricular tachycardia
0.000 0.068 0.932
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.070 0.930
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.072 0.928
K82 Other diseases of gallbladder
0.000 0.073 0.927
K60 Fissure and fistula of anal and rectal regions
0.000 0.073 0.927
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.074 0.926
I20.1 Angina pectoris with documented spasm
0.000 0.075 0.925
I46 Cardiac arrest
0.000 0.082 0.918
E11.1 With ketoacidosis
0.000 0.084 0.916
K51.8 Other ulcerative colitis
0.915 0.085 0.000
K82.8 Other specified diseases of gallbladder
0.000 0.085 0.915
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.086 0.914
K60.2 Anal fissure, unspecified
0.000 0.088 0.912
E13 Other specified diabetes mellitus
0.000 0.091 0.909
E07 Other disorders of thyroid
0.000 0.093 0.907
E05.9 Thyrotoxicosis, unspecified
0.000 0.098 0.902
E11.2 With renal complications
0.000 0.098 0.902
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.100 0.900
K50 Crohn's disease [regional enteritis]
0.001 0.103 0.896
K72 Hepatic failure, not elsewhere classified
0.000 0.104 0.896
E11.5 With peripheral circulatory complications
0.000 0.105 0.895
E10.2 With renal complications
0.000 0.109 0.891
G37.8 Other specified demyelinating diseases of central nervous system
0.890 0.110 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.112 0.888
J45 Asthma
0.000 0.112 0.888
I46.9 Cardiac arrest, unspecified
0.000 0.118 0.882
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.119 0.881
I15 Secondary hypertension
0.000 0.123 0.877
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.126 0.874
H34.2 Other retinal artery occlusions
0.000 0.126 0.874
I21.9 Acute myocardial infarction, unspecified
0.000 0.128 0.872
K51.2 Ulcerative (chronic) proctitis
0.871 0.129 0.000
K55 Vascular disorders of intestine
0.000 0.131 0.869
M06.3 Rheumatoid nodule
0.000 0.132 0.868
E03.8 Other specified hypothyroidism
0.000 0.136 0.864
K60.0 Acute anal fissure
0.000 0.137 0.863
M07 Psoriatic and enteropathic arthropathies
0.000 0.138 0.862
K75 Other inflammatory liver diseases
0.000 0.141 0.859
I31 Other diseases of pericardium
0.000 0.143 0.857
E07.9 Disorder of thyroid, unspecified
0.000 0.146 0.854
J40-J47 Chronic lower respiratory diseases
0.000 0.147 0.853
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.149 0.851
Chapter X Diseases of the respiratory system
0.000 0.155 0.845
E13.9 Without complications
0.000 0.156 0.844
K60.5 Anorectal fistula
0.000 0.157 0.843
M06.4 Inflammatory polyarthropathy
0.000 0.157 0.843
I21.4 Acute subendocardial myocardial infarction
0.000 0.158 0.842
E83 Disorders of mineral metabolism
0.767 0.164 0.069
K81 Cholecystitis
0.000 0.166 0.834
K63 Other diseases of intestine
0.000 0.175 0.825
K73 Chronic hepatitis, not elsewhere classified
0.000 0.176 0.824
K55.2 Angiodysplasia of colon
0.000 0.177 0.823
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.182 0.818
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.182 0.818
E06 Thyroiditis
0.000 0.184 0.816
K80 Cholelithiasis
0.000 0.187 0.813
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.188 0.812
K51.5 Mucosal proctocolitis
0.811 0.189 0.000
K82.1 Hydrops of gallbladder
0.000 0.193 0.807
K74.6 Other and unspecified cirrhosis of liver
0.000 0.196 0.804
K72.9 Hepatic failure, unspecified
0.000 0.197 0.803
K50.8 Other Crohn's disease
0.000 0.204 0.796
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.207 0.793
E74 Other disorders of carbohydrate metabolism
0.000 0.209 0.791
H25-H28 Disorders of lens
0.000 0.211 0.789
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.215 0.785
K58 Irritable bowel syndrome
0.000 0.216 0.784
K75.4 Autoimmune hepatitis
0.000 0.216 0.784
E11.4 With neurological complications
0.000 0.218 0.782
L40.8 Other psoriasis
0.000 0.220 0.780
E16.1 Other hypoglycaemia
0.000 0.222 0.778
I35.8 Other aortic valve disorders
0.000 0.222 0.778
H40.1 Primary open-angle glaucoma
0.000 0.223 0.777
H34.8 Other retinal vascular occlusions
0.000 0.225 0.775
I15.1 Hypertension secondary to other renal disorders
0.000 0.226 0.774
H43.9 Disorder of vitreous body, unspecified
0.000 0.226 0.774
K63.9 Disease of intestine, unspecified
0.000 0.226 0.774
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.772 0.228 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.228 0.772
I31.3 Pericardial effusion (noninflammatory)
0.000 0.232 0.768
K81.9 Cholecystitis, unspecified
0.000 0.232 0.768
L43.8 Other lichen planus
0.000 0.233 0.767
M07.3 Other psoriatic arthropathies
0.000 0.234 0.766
K81.1 Chronic cholecystitis
0.000 0.234 0.766
I12.0 Hypertensive renal disease with renal failure
0.000 0.235 0.765
E40-E46 Malnutrition
0.000 0.236 0.763
I23 Certain current complications following acute myocardial infarction
0.000 0.238 0.762
M45-M49 Spondylopathies
0.000 0.239 0.761
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.240 0.760
E14.4 With neurological complications
0.000 0.241 0.758
K55.8 Other vascular disorders of intestine
0.000 0.243 0.757
E78.2 Mixed hyperlipidaemia
0.000 0.244 0.756
J46 Status asthmaticus
0.000 0.245 0.755
I25.3 Aneurysm of heart
0.000 0.245 0.755
M06.34 Rheumatoid nodule (Hand)
0.000 0.247 0.753
H30 Chorioretinal inflammation
0.000 0.248 0.752
K63.3 Ulcer of intestine
0.000 0.249 0.751
E11.0 With coma
0.000 0.249 0.750
K50.0 Crohn's disease of small intestine
0.000 0.251 0.749
H43.1 Vitreous haemorrhage
0.000 0.255 0.745
M45 Ankylosing spondylitis
0.000 0.256 0.744
I47.2 Ventricular tachycardia
0.000 0.259 0.741
E11.6 With other specified complications
0.000 0.260 0.740
K51.0 Ulcerative (chronic) enterocolitis
0.736 0.264 0.000
Chapter VIII Diseases of the ear and mastoid process
0.000 0.264 0.736
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.268 0.732
E83.3 Disorders of phosphorus metabolism
0.714 0.269 0.018
K50.9 Crohn's disease, unspecified
0.000 0.270 0.730
H27 Other disorders of lens
0.000 0.270 0.730
J95-J99 Other diseases of the respiratory system
0.000 0.271 0.729
K72.0 Acute and subacute hepatic failure
0.000 0.272 0.728
I47.0 Reentry ventricular arrhythmia
0.000 0.273 0.727
M11 Other crystal arthropathies
0.000 0.274 0.726
E88 Other metabolic disorders
0.000 0.274 0.726
J44 Other chronic obstructive pulmonary disease
0.000 0.275 0.725
K82.2 Perforation of gallbladder
0.000 0.278 0.721
K52 Other non-infective gastro-enteritis and colitis
0.002 0.279 0.718
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.280 0.720
I25.4 Coronary artery aneurysm
0.000 0.281 0.719
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
J86 Pyothorax
0.000 0.284 0.716
E06.3 Autoimmune thyroiditis
0.000 0.284 0.716
L43.3 Subacute (active) lichen planus
0.000 0.284 0.716
L43.2 Lichenoid drug reaction
0.000 0.284 0.716
L43.1 Bullous lichen planus
0.000 0.284 0.716
L43.0 Hypertrophic lichen planus
0.000 0.284 0.716
M06.8 Other specified rheumatoid arthritis
0.000 0.284 0.716
M06.2 Rheumatoid bursitis
0.000 0.284 0.716
M06.1 Adult-onset Still's disease
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.715
G36 Other acute disseminated demyelination
0.715 0.285 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.286 0.714
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.286 0.714
M08 Juvenile arthritis
0.000 0.286 0.714
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
K51.4 Pseudopolyposis of colon
0.712 0.288 0.000
E78.6 Lipoprotein deficiency
0.000 0.288 0.711
E78.3 Hyperchylomicronaemia
0.000 0.288 0.711
H34.1 Central retinal artery occlusion
0.000 0.289 0.711
E77 Disorders of glycoprotein metabolism
0.000 0.289 0.711
E76 Disorders of glycosaminoglycan metabolism
0.000 0.289 0.711
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.289 0.711
E72 Other disorders of amino-acid metabolism
0.000 0.289 0.711
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.289 0.711
E70 Disorders of aromatic amino-acid metabolism
0.000 0.289 0.711
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.289 0.711
M05.8 Other seropositive rheumatoid arthritis
0.000 0.291 0.709
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.291 0.709
M05.2 Rheumatoid vasculitis
0.000 0.291 0.709
M05.1 Rheumatoid lung disease
0.000 0.291 0.709
M05.0 Felty's syndrome
0.000 0.291 0.709
Chapter VI Diseases of the nervous system
0.704 0.291 0.005
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.292 0.708
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.292 0.708
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.293 0.707
H42 Glaucoma in diseases classified elsewhere
0.000 0.294 0.706
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.294 0.706
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.294 0.706
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.294 0.706
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.294 0.706
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.294 0.706
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.294 0.706
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.294 0.706
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.294 0.706
H43.2 Crystalline deposits in vitreous body
0.000 0.294 0.705
H43.0 Vitreous prolapse
0.000 0.294 0.705
K77 Liver disorders in diseases classified elsewhere
0.000 0.295 0.705
K71 Toxic liver disease
0.000 0.295 0.705
K82.9 Disease of gallbladder, unspecified
0.000 0.296 0.704
E78.1 Pure hyperglyceridaemia
0.000 0.297 0.703
K74.5 Biliary cirrhosis, unspecified
0.000 0.300 0.700
K50.1 Crohn's disease of large intestine
0.000 0.300 0.700
M65-M68 Disorders of synovium and tendon
0.000 0.301 0.699
H40.6 Glaucoma secondary to drugs
0.000 0.302 0.698
H40.4 Glaucoma secondary to eye inflammation
0.000 0.302 0.698
H40.3 Glaucoma secondary to eye trauma
0.000 0.302 0.698
K51.1 Ulcerative (chronic) ileocolitis
0.697 0.302 0.000
I52 Other heart disorders in diseases classified elsewhere
0.000 0.304 0.696
I48 Atrial fibrillation and flutter
0.000 0.304 0.696
I41 Myocarditis in diseases classified elsewhere
0.000 0.304 0.696
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.304 0.696
I32 Pericarditis in diseases classified elsewhere
0.000 0.304 0.696
I51 Complications and ill-defined descriptions of heart disease
0.000 0.304 0.696
G80-G83 Cerebral palsy and other paralytic syndromes
0.693 0.305 0.001
I11 Hypertensive heart disease
0.000 0.306 0.694
H40.5 Glaucoma secondary to other eye disorders
0.000 0.306 0.694
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.306 0.694
E11.8 With unspecified complications
0.000 0.306 0.694
I31.9 Disease of pericardium, unspecified
0.000 0.308 0.692
E89.3 Postprocedural hypopituitarism
0.000 0.310 0.690
E78.8 Other disorders of lipoprotein metabolism
0.000 0.310 0.690
K74.4 Secondary biliary cirrhosis
0.000 0.312 0.688
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.312 0.688
K74.1 Hepatic sclerosis
0.000 0.312 0.688
L40.0 Psoriasis vulgaris
0.000 0.319 0.681
H60-H62 Diseases of external ear
0.000 0.320 0.680
L42 Pityriasis rosea
0.000 0.320 0.680
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.322 0.678
H34.9 Retinal vascular occlusion, unspecified
0.000 0.322 0.677
H34.0 Transient retinal artery occlusion
0.000 0.322 0.677
I30 Acute pericarditis
0.000 0.324 0.676
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.326 0.674
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.326 0.674
E79 Disorders of purine and pyrimidine metabolism
0.000 0.326 0.673
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.327 0.673
K82.3 Fistula of gallbladder
0.000 0.327 0.673
K73.9 Chronic hepatitis, unspecified
0.000 0.327 0.673
I51.8 Other ill-defined heart diseases
0.000 0.330 0.670
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.331 0.669
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.332 0.667
K90.9 Intestinal malabsorption, unspecified
0.000 0.333 0.667
E05.5 Thyroid crisis or storm
0.000 0.333 0.667
E05.4 Thyrotoxicosis factitia
0.000 0.333 0.667
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.333 0.667
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.333 0.667
K63.4 Enteroptosis
0.000 0.335 0.665
E89.0 Postprocedural hypothyroidism
0.000 0.335 0.665
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.336 0.664
I15.9 Seconday hypertension, unspecified
0.000 0.336 0.664
H35 Other retinal disorders
0.000 0.338 0.662
G83 Other paralytic syndromes
0.661 0.339 0.000
G81 Hemiplegia
0.661 0.339 0.001
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.339 0.661
E78.4 Other hyperlipidaemia
0.000 0.340 0.660
E84 Cystic fibrosis
0.000 0.341 0.659
I46.1 Sudden cardiac death, so described
0.000 0.341 0.658
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.342 0.658
E89.2 Postprocedural hypoparathyroidism
0.000 0.342 0.658
J43 Emphysema
0.000 0.343 0.657
E83.9 Disorder of mineral metabolism, unspecified
0.615 0.343 0.042
M14 Arthropathies in other diseases classified elsewhere
0.000 0.343 0.656
I44 Atrioventricular and left bundle-branch block
0.000 0.344 0.656
I40 Acute myocarditis
0.000 0.344 0.655
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.346 0.654
M12 Other specific arthropathies
0.000 0.348 0.652
E13.8 With unspecified complications
0.000 0.348 0.652
E13.7 With multiple complications
0.000 0.348 0.652
E13.6 With other specified complications
0.000 0.348 0.652
E13.5 With peripheral circulatory complications
0.000 0.348 0.652
E13.4 With neurological complications
0.000 0.348 0.652
E13.3 With ophthalmic complications
0.000 0.348 0.652
E13.2 With renal complications
0.000 0.348 0.652
E13.1 With ketoacidosis
0.000 0.348 0.652
E13.0 With coma
0.000 0.348 0.652
K55.1 Chronic vascular disorders of intestine
0.000 0.348 0.651
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.349 0.651
K75.0 Abscess of liver
0.000 0.350 0.650
E07.1 Dyshormogenetic goitre
0.000 0.350 0.650
E07.0 Hypersecretion of calcitonin
0.000 0.350 0.650
M70-M79 Other soft tissue disorders
0.000 0.350 0.650
I46.0 Cardiac arrest with successful resuscitation
0.000 0.352 0.648
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.352 0.648
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.353 0.647
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.353 0.646
K80.8 Other cholelithiasis
0.000 0.355 0.645
K72.1 Chronic hepatic failure
0.000 0.357 0.643
Q60-Q64 Congenital malformations of the urinary system
0.000 0.358 0.642
H65-H75 Diseases of middle ear and mastoid
0.000 0.359 0.641
I22.8 Subsequent myocardial infarction of other sites
0.000 0.359 0.640
G81.9 Hemiplegia, unspecified
0.640 0.360 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.362 0.638
H53-H54 Visual disturbances and blindness
0.000 0.363 0.637
J45.8 Mixed asthma
0.000 0.364 0.636
J45.1 Nonallergic asthma
0.000 0.364 0.636
K90.8 Other intestinal malabsorption
0.000 0.364 0.636
K65-K67 Diseases of peritoneum
0.000 0.367 0.633
H27.8 Other specified disorders of lens
0.000 0.368 0.632
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.368 0.632
H27.0 Aphakia
0.000 0.369 0.631
K52.1 Toxic gastro-enteritis and colitis
0.001 0.369 0.630
J86.9 Pyothorax without fistula
0.000 0.370 0.630
Q61 Cystic kidney disease
0.000 0.370 0.630
I45 Other conduction disorders
0.000 0.370 0.630
I15.8 Other secondary hypertension
0.000 0.371 0.629
I15.2 Hypertension secondary to endocrine disorders
0.000 0.371 0.629
I15.0 Renovascular hypertension
0.000 0.371 0.629
G30-G32 Other degenerative diseases of the nervous system
0.626 0.372 0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.374 0.626
I37 Pulmonary valve disorders
0.000 0.375 0.625
M65 Synovitis and tenosynovitis
0.000 0.376 0.624
G83.4 Cauda equina syndrome
0.622 0.378 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.378 0.622
M06.38 Rheumatoid nodule (Other)
0.000 0.378 0.622
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.378 0.622
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.378 0.622
M06.33 Rheumatoid nodule (Forearm)
0.000 0.378 0.622
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.378 0.622
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.378 0.622
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.378 0.622
J86.0 Pyothorax with fistula
0.000 0.379 0.621
J98 Other respiratory disorders
0.000 0.379 0.621
M07.6 Other enteropathic arthropathies
0.000 0.382 0.618
M07.5 Arthropathy in ulcerative colitis
0.000 0.382 0.618
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.382 0.618
M07.2 Psoriatic spondylitis
0.000 0.382 0.618
M07.1 Arthritis mutilans
0.000 0.382 0.618
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.382 0.618
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.384 0.616
K75.2 Nonspecific reactive hepatitis
0.000 0.384 0.616
K75.1 Phlebitis of portal vein
0.000 0.384 0.616
K60.4 Rectal fistula
0.000 0.385 0.615
I31.8 Other specified diseases of pericardium
0.000 0.385 0.615
I31.2 Haemopericardium, not elsewhere classified
0.000 0.385 0.615
I31.0 Chronic adhesive pericarditis
0.000 0.385 0.615
J41 Simple and mucopurulent chronic bronchitis
0.000 0.388 0.611
K63.8 Other specified diseases of intestine
0.000 0.388 0.611
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.389 0.610
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.389 0.610
E89.5 Postprocedural testicular hypofunction
0.000 0.389 0.610
E89.1 Postprocedural hypoinsulinaemia
0.000 0.389 0.610
K75.9 Inflammatory liver disease, unspecified
0.000 0.390 0.609
H25 Senile cataract
0.000 0.391 0.609
M06.0 Seronegative rheumatoid arthritis
0.000 0.391 0.609
I24.1 Dressler's syndrome
0.000 0.392 0.608
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.392 0.607
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.393 0.607
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.395 0.605
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.396 0.604
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.396 0.604
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.396 0.604
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.396 0.604
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.396 0.604
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.396 0.604
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.396 0.604
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.396 0.604
I42 Cardiomyopathy
0.000 0.397 0.603
L10-L14 Bullous disorders
0.000 0.397 0.602
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.398 0.602
H60 Otitis externa
0.000 0.398 0.602
E83.8 Other disorders of mineral metabolism
0.550 0.400 0.049
E83.2 Disorders of zinc metabolism
0.550 0.400 0.049
E83.0 Disorders of copper metabolism
0.550 0.400 0.049
K82.0 Obstruction of gallbladder
0.000 0.401 0.599
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.405 0.595
E46 Unspecified protein-energy malnutrition
0.000 0.406 0.594
Q50-Q56 Congenital malformations of genital organs
0.000 0.406 0.594
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.406 0.593
I23.8 Other current complications following acute myocardial infarction
0.000 0.409 0.591
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.409 0.590
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.409 0.590
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.409 0.590
G20-G26 Extrapyramidal and movement disorders
0.588 0.410 0.001
I44.3 Other and unspecified atrioventricular block
0.000 0.414 0.586
E06.5 Other chronic thyroiditis
0.000 0.415 0.585
E06.4 Drug-induced thyroiditis
0.000 0.415 0.585
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.415 0.585
E06.1 Subacute thyroiditis
0.000 0.415 0.585
E06.0 Acute thyroiditis
0.000 0.415 0.585
K63.2 Fistula of intestine
0.000 0.415 0.585
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.416 0.584
E07.8 Other specified disorders of thyroid
0.000 0.416 0.584
K80.3 Calculus of bile duct with cholangitis
0.000 0.417 0.583
M46 Other inflammatory spondylopathies
0.000 0.417 0.583
H61 Other disorders of external ear
0.000 0.418 0.582
I36 Nonrheumatic tricuspid valve disorders
0.000 0.418 0.582
E89.4 Postprocedural ovarian failure
0.000 0.420 0.580
H25.1 Senile nuclear cataract
0.000 0.421 0.579
E05.8 Other thyrotoxicosis
0.000 0.421 0.579
H71 Cholesteatoma of middle ear
0.000 0.421 0.579

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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