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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132946
log Bayes Factor = 156.439
Chromosome 6   position 32,190,028  (GRCh37) Explore rs3132946 on Ensembl!
Variant rs3132946 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.001 0.999
I25 Chronic ischaemic heart disease
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
I20 Angina pectoris
0.000 0.001 0.999
E14 Unspecified diabetes mellitus
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
L43 Lichen planus
0.000 0.001 0.999
L43.9 Lichen planus, unspecified
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
K51.9 Ulcerative colitis, unspecified
0.996 0.004 0.000
K51 Ulcerative colitis
0.995 0.005 0.000
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.007 0.993
E70-E90 Metabolic disorders
0.000 0.008 0.992
L40.9 Psoriasis, unspecified
0.000 0.008 0.992
Chapter XI Diseases of the digestive system
0.000 0.009 0.991
M05 Seropositive rheumatoid arthritis
0.000 0.009 0.991
K90 Intestinal malabsorption
0.000 0.010 0.990
E14.3 With ophthalmic complications
0.000 0.010 0.990
G37.9 Demyelinating disease of central nervous system, unspecified
0.989 0.011 0.000
K90-K93 Other diseases of the digestive system
0.000 0.011 0.989
I22 Subsequent myocardial infarction
0.000 0.011 0.989
H43-H45 Disorders of vitreous body and globe
0.000 0.014 0.986
I20.0 Unstable angina
0.000 0.014 0.986
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.015 0.985
H40-H42 Glaucoma
0.000 0.016 0.984
K51.3 Ulcerative (chronic) rectosigmoiditis
0.984 0.016 0.000
I20.9 Angina pectoris, unspecified
0.000 0.018 0.982
H43 Disorders of vitreous body
0.000 0.019 0.981
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.020 0.980
E14.9 Without complications
0.000 0.021 0.979
E11.3 With ophthalmic complications
0.000 0.021 0.979
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.022 0.978
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.023 0.977
H40 Glaucoma
0.000 0.027 0.973
H40.9 Glaucoma, unspecified
0.000 0.027 0.973
I30-I52 Other forms of heart disease
0.000 0.028 0.972
E10.5 With peripheral circulatory complications
0.000 0.030 0.970
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.030 0.970
I25.1 Atherosclerotic heart disease
0.000 0.035 0.965
I47 Paroxysmal tachycardia
0.000 0.035 0.965
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.042 0.958
I47.1 Supraventricular tachycardia
0.000 0.044 0.956
I35 Nonrheumatic aortic valve disorders
0.000 0.045 0.955
H34 Retinal vascular occlusions
0.000 0.047 0.953
I35.0 Aortic (valve) stenosis
0.000 0.047 0.953
E07 Other disorders of thyroid
0.000 0.050 0.950
K55-K64 Other diseases of intestines
0.000 0.050 0.950
K70-K77 Diseases of liver
0.000 0.052 0.948
I24 Other acute ischaemic heart diseases
0.000 0.053 0.947
H43.8 Other disorders of vitreous body
0.000 0.054 0.946
K60 Fissure and fistula of anal and rectal regions
0.000 0.055 0.945
H43.3 Other vitreous opacities
0.000 0.057 0.943
I25.2 Old myocardial infarction
0.000 0.057 0.943
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.057 0.943
I25.5 Ischaemic cardiomyopathy
0.000 0.058 0.942
I12 Hypertensive renal disease
0.000 0.063 0.937
I20.1 Angina pectoris with documented spasm
0.000 0.063 0.937
M07 Psoriatic and enteropathic arthropathies
0.000 0.068 0.932
E11.1 With ketoacidosis
0.000 0.071 0.929
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.072 0.928
K51.8 Other ulcerative colitis
0.927 0.073 0.000
K60.2 Anal fissure, unspecified
0.000 0.075 0.925
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.076 0.924
E07.9 Disorder of thyroid, unspecified
0.000 0.078 0.922
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.087 0.913
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.088 0.912
K74 Fibrosis and cirrhosis of liver
0.000 0.089 0.911
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.089 0.911
E11.2 With renal complications
0.000 0.089 0.911
E11.5 With peripheral circulatory complications
0.000 0.093 0.907
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.094 0.906
J45.9 Asthma, unspecified
0.000 0.105 0.895
I12.9 Hypertensive renal disease without renal failure
0.000 0.107 0.893
H34.2 Other retinal artery occlusions
0.000 0.107 0.893
E10.2 With renal complications
0.000 0.108 0.892
E13 Other specified diabetes mellitus
0.000 0.108 0.892
K74.3 Primary biliary cirrhosis
0.000 0.108 0.892
K51.2 Ulcerative (chronic) proctitis
0.891 0.109 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.889 0.111 0.000
I46 Cardiac arrest
0.000 0.115 0.885
M07.3 Other psoriatic arthropathies
0.000 0.116 0.884
K60.0 Acute anal fissure
0.000 0.117 0.883
K58 Irritable bowel syndrome
0.000 0.120 0.880
K55 Vascular disorders of intestine
0.000 0.120 0.879
I31 Other diseases of pericardium
0.000 0.121 0.879
I15 Secondary hypertension
0.000 0.122 0.878
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.123 0.877
E03.8 Other specified hypothyroidism
0.000 0.126 0.874
E05.9 Thyrotoxicosis, unspecified
0.000 0.127 0.873
K50-K52 Noninfective enteritis and colitis
0.032 0.132 0.836
M45-M49 Spondylopathies
0.000 0.139 0.861
K60.5 Anorectal fistula
0.000 0.140 0.860
I21 Acute myocardial infarction
0.000 0.146 0.854
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.149 0.851
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.152 0.848
M45 Ankylosing spondylitis
0.000 0.152 0.848
K72 Hepatic failure, not elsewhere classified
0.000 0.153 0.847
M06.4 Inflammatory polyarthropathy
0.000 0.155 0.845
M06.3 Rheumatoid nodule
0.000 0.156 0.844
I46.9 Cardiac arrest, unspecified
0.000 0.157 0.843
E06 Thyroiditis
0.000 0.157 0.843
K51.5 Mucosal proctocolitis
0.839 0.161 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.163 0.837
E11.4 With neurological complications
0.000 0.166 0.834
H40.1 Primary open-angle glaucoma
0.000 0.168 0.832
K55.2 Angiodysplasia of colon
0.000 0.169 0.831
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.171 0.829
Chapter VIII Diseases of the ear and mastoid process
0.000 0.177 0.823
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.182 0.818
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.182 0.818
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.184 0.816
E13.9 Without complications
0.000 0.185 0.815
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.195 0.805
K63 Other diseases of intestine
0.000 0.196 0.804
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.202 0.798
K75 Other inflammatory liver diseases
0.000 0.204 0.796
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.206 0.793
E83 Disorders of mineral metabolism
0.703 0.207 0.090
H25-H28 Disorders of lens
0.000 0.208 0.792
E74 Other disorders of carbohydrate metabolism
0.000 0.208 0.792
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.211 0.789
I31.3 Pericardial effusion (noninflammatory)
0.000 0.213 0.787
H60-H62 Diseases of external ear
0.000 0.219 0.781
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.781 0.219 0.000
L40.8 Other psoriasis
0.000 0.220 0.780
K73 Chronic hepatitis, not elsewhere classified
0.000 0.220 0.780
E16.1 Other hypoglycaemia
0.000 0.221 0.779
I15.1 Hypertension secondary to other renal disorders
0.000 0.224 0.776
E11.0 With coma
0.000 0.229 0.771
K55.8 Other vascular disorders of intestine
0.000 0.229 0.771
K50 Crohn's disease [regional enteritis]
0.002 0.229 0.769
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.231 0.769
L43.8 Other lichen planus
0.000 0.232 0.768
E11.6 With other specified complications
0.000 0.233 0.767
I35.8 Other aortic valve disorders
0.000 0.234 0.766
H43.9 Disorder of vitreous body, unspecified
0.000 0.235 0.765
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.237 0.762
I23 Certain current complications following acute myocardial infarction
0.000 0.238 0.762
K63.9 Disease of intestine, unspecified
0.000 0.238 0.762
K72.9 Hepatic failure, unspecified
0.000 0.239 0.761
H34.8 Other retinal vascular occlusions
0.000 0.241 0.759
E14.4 With neurological complications
0.000 0.242 0.758
E06.3 Autoimmune thyroiditis
0.000 0.243 0.757
I25.3 Aneurysm of heart
0.000 0.244 0.756
I47.0 Reentry ventricular arrhythmia
0.000 0.253 0.747
E88 Other metabolic disorders
0.000 0.253 0.747
H34.1 Central retinal artery occlusion
0.000 0.257 0.743
I31.9 Disease of pericardium, unspecified
0.000 0.257 0.743
E40-E46 Malnutrition
0.000 0.260 0.740
I25.4 Coronary artery aneurysm
0.000 0.260 0.740
H27 Other disorders of lens
0.000 0.261 0.739
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.266 0.733
E78.2 Mixed hyperlipidaemia
0.000 0.267 0.733
M06.34 Rheumatoid nodule (Hand)
0.000 0.267 0.733
E78.1 Pure hyperglyceridaemia
0.000 0.268 0.732
H30 Chorioretinal inflammation
0.000 0.268 0.732
I30 Acute pericarditis
0.000 0.270 0.729
E78.8 Other disorders of lipoprotein metabolism
0.000 0.272 0.728
H65-H75 Diseases of middle ear and mastoid
0.000 0.272 0.728
I21.9 Acute myocardial infarction, unspecified
0.000 0.273 0.727
M11 Other crystal arthropathies
0.000 0.273 0.726
K75.4 Autoimmune hepatitis
0.000 0.274 0.726
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.279 0.721
M70-M79 Other soft tissue disorders
0.000 0.280 0.720
H43.1 Vitreous haemorrhage
0.000 0.281 0.719
H60 Otitis externa
0.000 0.281 0.719
I21.4 Acute subendocardial myocardial infarction
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.716
E14.8 With unspecified complications
0.000 0.283 0.716
E14.7 With multiple complications
0.000 0.283 0.716
E14.6 With other specified complications
0.000 0.283 0.716
E14.5 With peripheral circulatory complications
0.000 0.283 0.716
E14.2 Withrenal complications
0.000 0.283 0.716
E14.1 With ketoacidosis
0.000 0.283 0.716
E14.0 With coma
0.000 0.283 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
L43.3 Subacute (active) lichen planus
0.000 0.284 0.716
L43.2 Lichenoid drug reaction
0.000 0.284 0.716
L43.1 Bullous lichen planus
0.000 0.284 0.716
L43.0 Hypertrophic lichen planus
0.000 0.284 0.716
I11 Hypertensive heart disease
0.000 0.285 0.715
I44 Atrioventricular and left bundle-branch block
0.000 0.285 0.715
G36 Other acute disseminated demyelination
0.715 0.285 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.715 0.285 0.000
G37.5 Concentric sclerosis [Balo]
0.713 0.287 0.000
G37.4 Subacute necrotising myelitis
0.713 0.287 0.000
G37.2 Central pontine myelinolysis
0.713 0.287 0.000
G37.1 Central demyelination of corpus callosum
0.713 0.287 0.000
G37.0 Diffuse sclerosis
0.713 0.287 0.000
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
K63.3 Ulcer of intestine
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.711
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.711
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.288 0.711
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.711
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.711
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.711
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.711
M05.8 Other seropositive rheumatoid arthritis
0.000 0.290 0.710
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.290 0.710
M05.2 Rheumatoid vasculitis
0.000 0.290 0.710
M05.1 Rheumatoid lung disease
0.000 0.290 0.710
M05.0 Felty's syndrome
0.000 0.290 0.710
K90.3 Pancreatic steatorrhoea
0.000 0.290 0.710
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.290 0.710
K90.1 Tropical sprue
0.000 0.290 0.710
L42 Pityriasis rosea
0.000 0.290 0.710
Q60-Q64 Congenital malformations of the urinary system
0.000 0.290 0.710
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.291 0.709
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.292 0.708
Chapter VI Diseases of the nervous system
0.702 0.292 0.006
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.293 0.707
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.294 0.706
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.294 0.706
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.294 0.706
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.294 0.706
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.294 0.706
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.294 0.706
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.294 0.706
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.294 0.706
H42 Glaucoma in diseases classified elsewhere
0.000 0.294 0.706
L40.0 Psoriasis vulgaris
0.000 0.295 0.705
K51.1 Ulcerative (chronic) ileocolitis
0.704 0.296 0.000
H43.2 Crystalline deposits in vitreous body
0.000 0.296 0.704
H43.0 Vitreous prolapse
0.000 0.296 0.704
Q61 Cystic kidney disease
0.000 0.297 0.703
H40.6 Glaucoma secondary to drugs
0.000 0.302 0.698
H40.4 Glaucoma secondary to eye inflammation
0.000 0.302 0.698
H40.3 Glaucoma secondary to eye trauma
0.000 0.302 0.698
I52 Other heart disorders in diseases classified elsewhere
0.000 0.303 0.697
I48 Atrial fibrillation and flutter
0.000 0.303 0.697
I41 Myocarditis in diseases classified elsewhere
0.000 0.303 0.697
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.303 0.697
I32 Pericarditis in diseases classified elsewhere
0.000 0.303 0.697
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.304 0.696
I47.2 Ventricular tachycardia
0.000 0.304 0.696
H40.5 Glaucoma secondary to other eye disorders
0.000 0.304 0.695
E11.8 With unspecified complications
0.000 0.305 0.695
G80-G83 Cerebral palsy and other paralytic syndromes
0.692 0.307 0.001
M65-M68 Disorders of synovium and tendon
0.000 0.310 0.690
H35 Other retinal disorders
0.000 0.312 0.688
H34.9 Retinal vascular occlusion, unspecified
0.000 0.317 0.683
H34.0 Transient retinal artery occlusion
0.000 0.317 0.683
E89.3 Postprocedural hypopituitarism
0.000 0.317 0.683
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.317 0.682
E07.1 Dyshormogenetic goitre
0.000 0.318 0.681
E07.0 Hypersecretion of calcitonin
0.000 0.318 0.681
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.319 0.681
K77 Liver disorders in diseases classified elsewhere
0.000 0.320 0.679
K71 Toxic liver disease
0.000 0.320 0.679
E83.3 Disorders of phosphorus metabolism
0.656 0.321 0.023
H61 Other disorders of external ear
0.000 0.323 0.677
M46 Other inflammatory spondylopathies
0.000 0.324 0.676
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.325 0.675
K50.8 Other Crohn's disease
0.001 0.325 0.674
E79 Disorders of purine and pyrimidine metabolism
0.000 0.326 0.674
K74.6 Other and unspecified cirrhosis of liver
0.000 0.328 0.672
M07.6 Other enteropathic arthropathies
0.000 0.332 0.668
M07.5 Arthropathy in ulcerative colitis
0.000 0.332 0.668
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.332 0.668
M07.2 Psoriatic spondylitis
0.000 0.332 0.668
M07.1 Arthritis mutilans
0.000 0.332 0.668
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.332 0.668
I12.0 Hypertensive renal disease with renal failure
0.000 0.333 0.667
M14 Arthropathies in other diseases classified elsewhere
0.000 0.334 0.666
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.334 0.666
K74.5 Biliary cirrhosis, unspecified
0.000 0.335 0.665
I15.9 Seconday hypertension, unspecified
0.000 0.335 0.665
H66 Suppurative and unspecified otitis media
0.000 0.335 0.665
E78.4 Other hyperlipidaemia
0.000 0.339 0.661
K51.4 Pseudopolyposis of colon
0.661 0.339 0.000
E84 Cystic fibrosis
0.000 0.340 0.660
K55.1 Chronic vascular disorders of intestine
0.000 0.340 0.660
E89.0 Postprocedural hypothyroidism
0.000 0.341 0.659
I45 Other conduction disorders
0.000 0.341 0.659
G81 Hemiplegia
0.658 0.342 0.001
H66.3 Other chronic suppurative otitis media
0.000 0.343 0.657
G83 Other paralytic syndromes
0.656 0.343 0.000
I40 Acute myocarditis
0.000 0.344 0.656
E89.2 Postprocedural hypoparathyroidism
0.000 0.344 0.656
M12 Other specific arthropathies
0.000 0.346 0.654
K74.4 Secondary biliary cirrhosis
0.000 0.346 0.653
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.346 0.653
K74.1 Hepatic sclerosis
0.000 0.346 0.653
Q61.0 Congenital single renal cyst
0.000 0.348 0.652
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.349 0.651
E05.5 Thyroid crisis or storm
0.000 0.351 0.649
E05.4 Thyrotoxicosis factitia
0.000 0.351 0.649
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.351 0.649
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.351 0.649
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.351 0.649
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.351 0.648
K72.0 Acute and subacute hepatic failure
0.000 0.352 0.648
Q61.3 Polycystic kidney, unspecified
0.000 0.352 0.648
M75 Shoulder lesions
0.000 0.355 0.645
H60.9 Otitis externa, unspecified
0.000 0.356 0.644
I51 Complications and ill-defined descriptions of heart disease
0.000 0.357 0.643
M06.0 Seronegative rheumatoid arthritis
0.000 0.358 0.641
I44.3 Other and unspecified atrioventricular block
0.000 0.359 0.641
M49 Spondylopathies in diseases classified elsewhere
0.000 0.359 0.641
I22.8 Subsequent myocardial infarction of other sites
0.000 0.359 0.641
H27.8 Other specified disorders of lens
0.000 0.359 0.641
H27.0 Aphakia
0.000 0.360 0.640
E13.8 With unspecified complications
0.000 0.360 0.640
E13.7 With multiple complications
0.000 0.360 0.640
E13.6 With other specified complications
0.000 0.360 0.640
E13.5 With peripheral circulatory complications
0.000 0.360 0.640
E13.4 With neurological complications
0.000 0.360 0.640
E13.3 With ophthalmic complications
0.000 0.360 0.640
E13.2 With renal complications
0.000 0.360 0.640
E13.1 With ketoacidosis
0.000 0.360 0.640
E13.0 With coma
0.000 0.360 0.640
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.361 0.638
K73.9 Chronic hepatitis, unspecified
0.000 0.362 0.638
G81.9 Hemiplegia, unspecified
0.637 0.363 0.000
M75.0 Adhesive capsulitis of shoulder
0.000 0.364 0.636
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.365 0.635
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.365 0.635
I46.1 Sudden cardiac death, so described
0.000 0.365 0.634
M07.38 Other psoriatic arthropathies (Other)
0.000 0.366 0.634
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.366 0.634
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.366 0.634
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.366 0.634
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.366 0.634
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.366 0.634
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.366 0.634
K90.8 Other intestinal malabsorption
0.000 0.368 0.631
I31.8 Other specified diseases of pericardium
0.000 0.370 0.630
I31.2 Haemopericardium, not elsewhere classified
0.000 0.370 0.630
I31.0 Chronic adhesive pericarditis
0.000 0.370 0.630
I15.8 Other secondary hypertension
0.000 0.370 0.630
I15.2 Hypertension secondary to endocrine disorders
0.000 0.370 0.630
I15.0 Renovascular hypertension
0.000 0.370 0.630
M86-M90 Other osteopathies
0.000 0.371 0.628
Q50-Q56 Congenital malformations of genital organs
0.000 0.371 0.629
K63.4 Enteroptosis
0.000 0.372 0.628
H71 Cholesteatoma of middle ear
0.000 0.372 0.628
K60.4 Rectal fistula
0.000 0.372 0.628
K50.0 Crohn's disease of small intestine
0.000 0.374 0.626
I37 Pulmonary valve disorders
0.000 0.374 0.626
Q61.2 Polycystic kidney, adult type
0.000 0.377 0.623
K90.9 Intestinal malabsorption, unspecified
0.000 0.381 0.619
G30-G32 Other degenerative diseases of the nervous system
0.616 0.381 0.003
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.384 0.616
I24.1 Dressler's syndrome
0.000 0.386 0.614
I51.8 Other ill-defined heart diseases
0.000 0.386 0.614
E07.8 Other specified disorders of thyroid
0.000 0.387 0.613
I44.0 Atrioventricular block, first degree
0.000 0.387 0.613
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.388 0.612
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.389 0.611
G83.4 Cauda equina syndrome
0.611 0.389 0.000
J45 Asthma
0.000 0.389 0.611
G20-G26 Extrapyramidal and movement disorders
0.608 0.390 0.002
I36 Nonrheumatic tricuspid valve disorders
0.000 0.391 0.609
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.392 0.608
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.392 0.608
E89.5 Postprocedural testicular hypofunction
0.000 0.392 0.608
E89.1 Postprocedural hypoinsulinaemia
0.000 0.392 0.608
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.392 0.608
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.392 0.608
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.392 0.608
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.392 0.608
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.392 0.608
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.392 0.608
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.392 0.608
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.392 0.608
K72.1 Chronic hepatic failure
0.000 0.392 0.607
M72 Fibroblastic disorders
0.000 0.393 0.607
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.394 0.606
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.394 0.606
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.394 0.606
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.394 0.606
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.394 0.606
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.394 0.606
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.394 0.606
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.394 0.606
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.394 0.605
M06.38 Rheumatoid nodule (Other)
0.000 0.394 0.605
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.394 0.605
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.394 0.605
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.394 0.605
M06.33 Rheumatoid nodule (Forearm)
0.000 0.394 0.605
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.394 0.605
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.394 0.605
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.394 0.605
L10-L14 Bullous disorders
0.000 0.395 0.605
H53-H54 Visual disturbances and blindness
0.000 0.396 0.604
E06.5 Other chronic thyroiditis
0.000 0.396 0.604
E06.4 Drug-induced thyroiditis
0.000 0.396 0.604
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.396 0.604
E06.1 Subacute thyroiditis
0.000 0.396 0.604
E06.0 Acute thyroiditis
0.000 0.396 0.604
K82 Other diseases of gallbladder
0.000 0.397 0.603
H35.8 Other specified retinal disorders
0.000 0.402 0.598
M65 Synovitis and tenosynovitis
0.000 0.404 0.596
K82.8 Other specified diseases of gallbladder
0.000 0.406 0.594
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.406 0.594
K63.8 Other specified diseases of intestine
0.000 0.407 0.593
H74 Other disorders of middle ear and mastoid
0.000 0.407 0.593
I23.8 Other current complications following acute myocardial infarction
0.000 0.408 0.592
M75.2 Bicipital tendinitis
0.000 0.412 0.588
K75.9 Inflammatory liver disease, unspecified
0.000 0.412 0.588
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.413 0.587
H25 Senile cataract
0.000 0.413 0.586
M60-M63 Disorders of muscles
0.000 0.418 0.582
H61.1 Non-infective disorders of pinna
0.000 0.419 0.581
I30.9 Acute pericarditis, unspecified
0.000 0.420 0.580
K50.9 Crohn's disease, unspecified
0.000 0.421 0.579
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.421 0.579
K50.1 Crohn's disease of large intestine
0.000 0.422 0.577
E89.4 Postprocedural ovarian failure
0.000 0.422 0.577
K65-K67 Diseases of peritoneum
0.000 0.424 0.576
H35.2 Other proliferative retinopathy
0.000 0.425 0.575
E73 Lactose intolerance
0.000 0.426 0.573
I45.5 Other specified heart block
0.000 0.427 0.573
G20 Parkinson's disease
0.571 0.429 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.429 0.571
K75.2 Nonspecific reactive hepatitis
0.000 0.429 0.571
K75.1 Phlebitis of portal vein
0.000 0.429 0.571
H27.1 Dislocation of lens
0.000 0.429 0.571
E83.9 Disorder of mineral metabolism, unspecified
0.504 0.431 0.065
E83.8 Other disorders of mineral metabolism
0.504 0.431 0.065
E83.2 Disorders of zinc metabolism
0.504 0.431 0.065
E83.0 Disorders of copper metabolism
0.504 0.431 0.065
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.432 0.568
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.432 0.568
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.432 0.568
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.432 0.568
E74.2 Disorders of galactose metabolism
0.000 0.432 0.568
E74.1 Disorders of fructose metabolism
0.000 0.432 0.568

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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