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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3134954
log Bayes Factor = 147.413
Chromosome 6   position 32,071,893  (GRCh37) Explore rs3134954 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E11.9 Without complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
M06 Other rheumatoid arthritis
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.999 0.001 0.000
I20 Angina pectoris
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
M05-M14 Inflammatory polyarthropathies
0.000 0.002 0.998
J45.9 Asthma, unspecified
0.000 0.003 0.997
I30-I52 Other forms of heart disease
0.000 0.003 0.997
E14.9 Without complications
0.000 0.003 0.997
E10.4 With neurological complications
0.000 0.003 0.997
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
K70-K77 Diseases of liver
0.000 0.003 0.997
L43 Lichen planus
0.000 0.004 0.996
I47 Paroxysmal tachycardia
0.000 0.004 0.996
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.005 0.995
I20.0 Unstable angina
0.000 0.005 0.995
I35.0 Aortic (valve) stenosis
0.000 0.006 0.994
I35 Nonrheumatic aortic valve disorders
0.000 0.006 0.994
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.006 0.994
L43.9 Lichen planus, unspecified
0.000 0.008 0.992
E14.3 With ophthalmic complications
0.000 0.008 0.992
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.008 0.992
I22 Subsequent myocardial infarction
0.000 0.008 0.992
K74 Fibrosis and cirrhosis of liver
0.000 0.010 0.990
E70-E90 Metabolic disorders
0.000 0.010 0.990
M05 Seropositive rheumatoid arthritis
0.000 0.013 0.987
I47.1 Supraventricular tachycardia
0.000 0.013 0.987
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.016 0.984
I25.1 Atherosclerotic heart disease
0.000 0.017 0.983
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.020 0.980
H43-H45 Disorders of vitreous body and globe
0.000 0.021 0.979
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.022 0.978
I20.9 Angina pectoris, unspecified
0.000 0.026 0.974
K74.3 Primary biliary cirrhosis
0.000 0.026 0.974
H43 Disorders of vitreous body
0.000 0.028 0.972
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.028 0.972
I25.5 Ischaemic cardiomyopathy
0.000 0.029 0.971
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.030 0.969
I24 Other acute ischaemic heart diseases
0.000 0.032 0.968
K82 Other diseases of gallbladder
0.000 0.033 0.967
H40-H42 Glaucoma
0.000 0.037 0.963
K80 Cholelithiasis
0.000 0.039 0.961
K81 Cholecystitis
0.000 0.039 0.961
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.039 0.961
E07 Other disorders of thyroid
0.000 0.043 0.957
H34 Retinal vascular occlusions
0.000 0.050 0.950
E11.3 With ophthalmic complications
0.000 0.051 0.949
E83 Disorders of mineral metabolism
0.931 0.052 0.017
E10.5 With peripheral circulatory complications
0.000 0.053 0.947
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.055 0.945
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.055 0.945
H43.3 Other vitreous opacities
0.000 0.060 0.940
H40 Glaucoma
0.000 0.062 0.938
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.063 0.937
H40.9 Glaucoma, unspecified
0.000 0.063 0.937
K72 Hepatic failure, not elsewhere classified
0.000 0.063 0.937
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.063 0.937
K82.8 Other specified diseases of gallbladder
0.000 0.066 0.934
M07 Psoriatic and enteropathic arthropathies
0.000 0.067 0.933
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.070 0.930
E07.9 Disorder of thyroid, unspecified
0.000 0.070 0.930
K81.1 Chronic cholecystitis
0.000 0.073 0.927
K51 Ulcerative colitis
0.923 0.077 0.000
I47.2 Ventricular tachycardia
0.000 0.078 0.922
K51.9 Ulcerative colitis, unspecified
0.921 0.079 0.000
K81.9 Cholecystitis, unspecified
0.000 0.082 0.918
H43.8 Other disorders of vitreous body
0.000 0.084 0.916
K51.3 Ulcerative (chronic) rectosigmoiditis
0.916 0.084 0.000
I25.2 Old myocardial infarction
0.000 0.085 0.915
K74.6 Other and unspecified cirrhosis of liver
0.000 0.091 0.909
J45 Asthma
0.000 0.092 0.908
I46 Cardiac arrest
0.000 0.097 0.903
E11.1 With ketoacidosis
0.000 0.098 0.902
E11.2 With renal complications
0.000 0.106 0.894
K82.1 Hydrops of gallbladder
0.000 0.108 0.892
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.110 0.890
G37.8 Other specified demyelinating diseases of central nervous system
0.888 0.112 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.112 0.888
K50-K52 Noninfective enteritis and colitis
0.023 0.113 0.864
M07.3 Other psoriatic arthropathies
0.000 0.113 0.887
K75 Other inflammatory liver diseases
0.000 0.113 0.887
J40-J47 Chronic lower respiratory diseases
0.000 0.114 0.886
I21 Acute myocardial infarction
0.000 0.115 0.885
Chapter X Diseases of the respiratory system
0.000 0.120 0.880
E83.3 Disorders of phosphorus metabolism
0.874 0.122 0.004
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.123 0.877
H34.2 Other retinal artery occlusions
0.000 0.130 0.870
E10.2 With renal complications
0.000 0.131 0.869
K72.9 Hepatic failure, unspecified
0.000 0.136 0.864
I46.9 Cardiac arrest, unspecified
0.000 0.140 0.860
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.141 0.859
I20.1 Angina pectoris with documented spasm
0.000 0.151 0.849
E03.8 Other specified hypothyroidism
0.000 0.151 0.849
E11.5 With peripheral circulatory complications
0.000 0.153 0.847
I15 Secondary hypertension
0.000 0.155 0.845
K73 Chronic hepatitis, not elsewhere classified
0.000 0.160 0.840
E11.0 With coma
0.000 0.161 0.839
E13 Other specified diabetes mellitus
0.000 0.164 0.836
E83.5 Disorders of calcium metabolism
0.833 0.166 0.001
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.170 0.830
K51.8 Other ulcerative colitis
0.828 0.172 0.000
M06.3 Rheumatoid nodule
0.000 0.174 0.826
M06.4 Inflammatory polyarthropathy
0.000 0.175 0.825
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.824 0.176 0.000
I47.0 Reentry ventricular arrhythmia
0.000 0.177 0.823
E06 Thyroiditis
0.000 0.179 0.821
I12 Hypertensive renal disease
0.000 0.182 0.818
I21.9 Acute myocardial infarction, unspecified
0.000 0.185 0.815
H34.8 Other retinal vascular occlusions
0.000 0.186 0.814
K74.5 Biliary cirrhosis, unspecified
0.000 0.187 0.813
M06.0 Seronegative rheumatoid arthritis
0.000 0.187 0.813
M65-M68 Disorders of synovium and tendon
0.000 0.188 0.812
E16.1 Other hypoglycaemia
0.000 0.189 0.811
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.190 0.810
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.192 0.808
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.198 0.802
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.198 0.802
L43.8 Other lichen planus
0.000 0.199 0.801
K55-K64 Other diseases of intestines
0.000 0.200 0.800
J46 Status asthmaticus
0.000 0.201 0.799
K51.2 Ulcerative (chronic) proctitis
0.798 0.202 0.000
K50 Crohn's disease [regional enteritis]
0.001 0.202 0.797
Chapter VI Diseases of the nervous system
0.783 0.208 0.008
E78.2 Mixed hyperlipidaemia
0.000 0.209 0.790
K60 Fissure and fistula of anal and rectal regions
0.000 0.210 0.790
L40.8 Other psoriasis
0.000 0.211 0.789
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.213 0.787
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.214 0.786
I25.3 Aneurysm of heart
0.000 0.215 0.785
J86 Pyothorax
0.000 0.216 0.784
I31 Other diseases of pericardium
0.000 0.218 0.782
K72.0 Acute and subacute hepatic failure
0.000 0.218 0.782
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.219 0.781
E83.9 Disorder of mineral metabolism, unspecified
0.766 0.224 0.010
K75.4 Autoimmune hepatitis
0.000 0.224 0.776
K60.2 Anal fissure, unspecified
0.000 0.225 0.775
K80.8 Other cholelithiasis
0.000 0.225 0.775
E40-E46 Malnutrition
0.000 0.227 0.772
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.229 0.771
L40.0 Psoriasis vulgaris
0.000 0.229 0.771
E11.6 With other specified complications
0.000 0.230 0.770
M65 Synovitis and tenosynovitis
0.000 0.234 0.766
E14.4 With neurological complications
0.000 0.234 0.765
K82.2 Perforation of gallbladder
0.000 0.239 0.761
I25.4 Coronary artery aneurysm
0.000 0.239 0.761
E74 Other disorders of carbohydrate metabolism
0.000 0.240 0.759
M14 Arthropathies in other diseases classified elsewhere
0.000 0.243 0.757
H30 Chorioretinal inflammation
0.000 0.243 0.757
I30 Acute pericarditis
0.000 0.247 0.753
J95-J99 Other diseases of the respiratory system
0.000 0.248 0.752
H40.1 Primary open-angle glaucoma
0.000 0.250 0.750
I23 Certain current complications following acute myocardial infarction
0.000 0.252 0.748
E78.8 Other disorders of lipoprotein metabolism
0.000 0.254 0.746
E78.1 Pure hyperglyceridaemia
0.000 0.254 0.745
E88 Other metabolic disorders
0.000 0.259 0.740
G80-G83 Cerebral palsy and other paralytic syndromes
0.737 0.261 0.002
G20-G26 Extrapyramidal and movement disorders
0.736 0.262 0.002
H43.2 Crystalline deposits in vitreous body
0.000 0.262 0.738
I21.4 Acute subendocardial myocardial infarction
0.000 0.267 0.733
I35.8 Other aortic valve disorders
0.000 0.267 0.733
I45 Other conduction disorders
0.000 0.267 0.733
K60.0 Acute anal fissure
0.000 0.272 0.728
K51.4 Pseudopolyposis of colon
0.727 0.273 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.273 0.727
H43.9 Disorder of vitreous body, unspecified
0.000 0.275 0.725
H34.1 Central retinal artery occlusion
0.000 0.275 0.725
K51.5 Mucosal proctocolitis
0.724 0.276 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.276 0.724
L42 Pityriasis rosea
0.000 0.281 0.719
E13.9 Without complications
0.000 0.281 0.719
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.282 0.718
I51 Complications and ill-defined descriptions of heart disease
0.000 0.282 0.718
I44 Atrioventricular and left bundle-branch block
0.000 0.282 0.718
J43 Emphysema
0.000 0.282 0.718
I12.9 Hypertensive renal disease without renal failure
0.000 0.283 0.717
K58 Irritable bowel syndrome
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.716
M06.2 Rheumatoid bursitis
0.000 0.283 0.716
M06.1 Adult-onset Still's disease
0.000 0.283 0.716
G36 Other acute disseminated demyelination
0.716 0.283 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.285 0.715
M08 Juvenile arthritis
0.000 0.285 0.715
I52 Other heart disorders in diseases classified elsewhere
0.000 0.285 0.715
I48 Atrial fibrillation and flutter
0.000 0.285 0.715
I41 Myocarditis in diseases classified elsewhere
0.000 0.285 0.715
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.285 0.715
I32 Pericarditis in diseases classified elsewhere
0.000 0.285 0.715
G20 Parkinson's disease
0.715 0.285 0.000
K77 Liver disorders in diseases classified elsewhere
0.000 0.285 0.715
K71 Toxic liver disease
0.000 0.285 0.715
K75.8 Other specified inflammatory liver diseases
0.000 0.286 0.714
L43.3 Subacute (active) lichen planus
0.000 0.286 0.714
L43.2 Lichenoid drug reaction
0.000 0.286 0.714
L43.1 Bullous lichen planus
0.000 0.286 0.714
L43.0 Hypertrophic lichen planus
0.000 0.286 0.714
H43.1 Vitreous haemorrhage
0.000 0.287 0.713
M11 Other crystal arthropathies
0.000 0.287 0.713
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.287 0.712
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.288 0.712
I15.1 Hypertension secondary to other renal disorders
0.000 0.288 0.712
M06.34 Rheumatoid nodule (Hand)
0.000 0.288 0.712
E78.6 Lipoprotein deficiency
0.000 0.289 0.711
E78.3 Hyperchylomicronaemia
0.000 0.289 0.711
K82.3 Fistula of gallbladder
0.000 0.289 0.711
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.290 0.710
K74.4 Secondary biliary cirrhosis
0.000 0.290 0.710
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.290 0.710
K74.1 Hepatic sclerosis
0.000 0.290 0.710
J86.9 Pyothorax without fistula
0.000 0.290 0.710
E06.3 Autoimmune thyroiditis
0.000 0.290 0.710
E77 Disorders of glycoprotein metabolism
0.000 0.290 0.710
E76 Disorders of glycosaminoglycan metabolism
0.000 0.290 0.710
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.290 0.710
E72 Other disorders of amino-acid metabolism
0.000 0.290 0.710
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.290 0.710
E70 Disorders of aromatic amino-acid metabolism
0.000 0.290 0.710
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.290 0.710
E78.4 Other hyperlipidaemia
0.000 0.291 0.709
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.291 0.709
M05.8 Other seropositive rheumatoid arthritis
0.000 0.292 0.708
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.292 0.708
M05.2 Rheumatoid vasculitis
0.000 0.292 0.708
M05.1 Rheumatoid lung disease
0.000 0.292 0.708
M05.0 Felty's syndrome
0.000 0.292 0.708
I11 Hypertensive heart disease
0.000 0.293 0.707
G30-G32 Other degenerative diseases of the nervous system
0.702 0.295 0.003
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.295 0.705
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.297 0.702
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.297 0.702
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.297 0.702
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.297 0.702
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.297 0.702
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.297 0.702
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.297 0.702
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.297 0.702
K63 Other diseases of intestine
0.000 0.298 0.702
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.298 0.702
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.301 0.699
H43.0 Vitreous prolapse
0.000 0.303 0.697
I31.3 Pericardial effusion (noninflammatory)
0.000 0.304 0.696
H40.4 Glaucoma secondary to eye inflammation
0.000 0.305 0.695
J44 Other chronic obstructive pulmonary disease
0.000 0.308 0.692
I51.8 Other ill-defined heart diseases
0.000 0.309 0.691
H42 Glaucoma in diseases classified elsewhere
0.000 0.309 0.690
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.311 0.689
K80.3 Calculus of bile duct with cholangitis
0.000 0.311 0.689
J86.0 Pyothorax with fistula
0.000 0.313 0.687
E07.1 Dyshormogenetic goitre
0.000 0.313 0.686
E07.0 Hypersecretion of calcitonin
0.000 0.313 0.686
J98 Other respiratory disorders
0.000 0.316 0.684
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.316 0.684
H34.9 Retinal vascular occlusion, unspecified
0.000 0.318 0.681
H34.0 Transient retinal artery occlusion
0.000 0.318 0.681
K73.9 Chronic hepatitis, unspecified
0.000 0.319 0.681
E11.8 With unspecified complications
0.000 0.320 0.680
E83.8 Other disorders of mineral metabolism
0.668 0.320 0.012
E83.2 Disorders of zinc metabolism
0.668 0.320 0.012
E83.0 Disorders of copper metabolism
0.668 0.320 0.012
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.321 0.679
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.322 0.678
I40 Acute myocarditis
0.000 0.324 0.676
K51.0 Ulcerative (chronic) enterocolitis
0.676 0.324 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.324 0.676
K60.5 Anorectal fistula
0.000 0.325 0.675
K50.8 Other Crohn's disease
0.000 0.325 0.675
K90.8 Other intestinal malabsorption
0.000 0.325 0.675
K55 Vascular disorders of intestine
0.000 0.326 0.674
H40.6 Glaucoma secondary to drugs
0.000 0.327 0.672
H40.3 Glaucoma secondary to eye trauma
0.000 0.327 0.672
K72.1 Chronic hepatic failure
0.000 0.328 0.672
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.329 0.671
G83 Other paralytic syndromes
0.669 0.331 0.001
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.331 0.669
M07.6 Other enteropathic arthropathies
0.000 0.331 0.669
M07.5 Arthropathy in ulcerative colitis
0.000 0.331 0.669
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.331 0.669
M07.2 Psoriatic spondylitis
0.000 0.331 0.669
M07.1 Arthritis mutilans
0.000 0.331 0.669
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.331 0.669
M45-M49 Spondylopathies
0.000 0.332 0.668
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.333 0.667
K50.0 Crohn's disease of small intestine
0.000 0.335 0.665
E11.4 With neurological complications
0.000 0.337 0.663
K51.1 Ulcerative (chronic) ileocolitis
0.661 0.338 0.000
E84 Cystic fibrosis
0.000 0.339 0.661
K75.0 Abscess of liver
0.000 0.339 0.661
E07.8 Other specified disorders of thyroid
0.000 0.339 0.661
K82.0 Obstruction of gallbladder
0.000 0.340 0.660
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.341 0.658
M12 Other specific arthropathies
0.000 0.342 0.658
G30 Alzheimer's disease
0.656 0.342 0.001
J98.4 Other disorders of lung
0.000 0.343 0.657
M45 Ankylosing spondylitis
0.000 0.344 0.656
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.348 0.652
J45.8 Mixed asthma
0.000 0.349 0.651
J45.1 Nonallergic asthma
0.000 0.349 0.651
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.349 0.650
I46.1 Sudden cardiac death, so described
0.000 0.353 0.647
I45.2 Bifascicular block
0.000 0.353 0.647
I15.9 Seconday hypertension, unspecified
0.000 0.353 0.647
K63.9 Disease of intestine, unspecified
0.000 0.354 0.646
I36 Nonrheumatic tricuspid valve disorders
0.000 0.354 0.646
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.357 0.642
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.358 0.642
J85 Abscess of lung and mediastinum
0.000 0.359 0.641
G81 Hemiplegia
0.639 0.360 0.001
I44.7 Left bundle-branch block, unspecified
0.000 0.362 0.638
M07.38 Other psoriatic arthropathies (Other)
0.000 0.364 0.636
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.364 0.636
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.364 0.636
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.364 0.636
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.364 0.636
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.364 0.636
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.364 0.636
K75.2 Nonspecific reactive hepatitis
0.000 0.364 0.636
K75.1 Phlebitis of portal vein
0.000 0.364 0.636
J41 Simple and mucopurulent chronic bronchitis
0.000 0.364 0.635
K82.9 Disease of gallbladder, unspecified
0.000 0.365 0.635
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.366 0.634
I24.1 Dressler's syndrome
0.000 0.366 0.634
I22.8 Subsequent myocardial infarction of other sites
0.000 0.366 0.634
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.369 0.631
E05.9 Thyrotoxicosis, unspecified
0.000 0.369 0.631
I44.3 Other and unspecified atrioventricular block
0.000 0.369 0.631
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.374 0.626
G30.9 Alzheimer's disease, unspecified
0.624 0.376 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.378 0.622
H40.5 Glaucoma secondary to other eye disorders
0.000 0.378 0.622
I37 Pulmonary valve disorders
0.000 0.379 0.621
K50.9 Crohn's disease, unspecified
0.000 0.379 0.621
J43.2 Centrilobular emphysema
0.000 0.383 0.617
K52 Other non-infective gastro-enteritis and colitis
0.004 0.383 0.613
G83.4 Cauda equina syndrome
0.615 0.385 0.000
I45.8 Other specified conduction disorders
0.000 0.386 0.614
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.390 0.610
E46 Unspecified protein-energy malnutrition
0.000 0.391 0.609
K81.8 Other cholecystitis
0.000 0.391 0.609
K55.2 Angiodysplasia of colon
0.000 0.393 0.607
I15.8 Other secondary hypertension
0.000 0.394 0.606
I15.2 Hypertension secondary to endocrine disorders
0.000 0.394 0.606
I15.0 Renovascular hypertension
0.000 0.394 0.606
K63.3 Ulcer of intestine
0.000 0.395 0.605
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.398 0.602
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.398 0.602
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.398 0.602
E73 Lactose intolerance
0.000 0.399 0.601
K50.1 Crohn's disease of large intestine
0.000 0.400 0.600
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.400 0.600
E13.8 With unspecified complications
0.000 0.400 0.599
E13.7 With multiple complications
0.000 0.400 0.599
E13.6 With other specified complications
0.000 0.400 0.599
E13.5 With peripheral circulatory complications
0.000 0.400 0.599
E13.4 With neurological complications
0.000 0.400 0.599
E13.3 With ophthalmic complications
0.000 0.400 0.599
E13.2 With renal complications
0.000 0.400 0.599
E13.1 With ketoacidosis
0.000 0.400 0.599
E13.0 With coma
0.000 0.400 0.599
K75.9 Inflammatory liver disease, unspecified
0.000 0.401 0.599
Q60-Q64 Congenital malformations of the urinary system
0.000 0.403 0.597
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.404 0.596
H31 Other disorders of choroid
0.000 0.406 0.594
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.406 0.594
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.407 0.592
M06.38 Rheumatoid nodule (Other)
0.000 0.407 0.592
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.407 0.592
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.407 0.592
M06.33 Rheumatoid nodule (Forearm)
0.000 0.407 0.592
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.407 0.592
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.407 0.592
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.407 0.592
M00-M03 Infectious arthropathies
0.000 0.408 0.592
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.408 0.592
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.408 0.592
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.408 0.592
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.408 0.592
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.408 0.592
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.408 0.592
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.408 0.592
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.408 0.592
E06.5 Other chronic thyroiditis
0.000 0.411 0.589
E06.4 Drug-induced thyroiditis
0.000 0.411 0.589
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.411 0.589
E06.1 Subacute thyroiditis
0.000 0.411 0.589
E06.0 Acute thyroiditis
0.000 0.411 0.589
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.413 0.587
M14.6 Neuropathic arthropathy
0.000 0.415 0.585
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.415 0.585
H30.9 Chorioretinal inflammation, unspecified
0.000 0.416 0.584
Q61 Cystic kidney disease
0.000 0.416 0.584
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.417 0.583
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.417 0.583
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.417 0.583
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.417 0.583
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.417 0.583
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.417 0.583
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.417 0.583
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.418 0.582
I30.9 Acute pericarditis, unspecified
0.000 0.421 0.579
K74.0 Hepatic fibrosis
0.000 0.421 0.579
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.425 0.575
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.426 0.574
G81.9 Hemiplegia, unspecified
0.574 0.426 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.426 0.574
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.426 0.573
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.427 0.573
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.428 0.571
I23.8 Other current complications following acute myocardial infarction
0.000 0.432 0.568
E89.2 Postprocedural hypoparathyroidism
0.000 0.434 0.566
I35.9 Aortic valve disorder, unspecified
0.000 0.434 0.565
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.560 0.436 0.005
I45.5 Other specified heart block
0.000 0.439 0.561
I31.8 Other specified diseases of pericardium
0.000 0.439 0.560
I31.2 Haemopericardium, not elsewhere classified
0.000 0.439 0.560
I31.0 Chronic adhesive pericarditis
0.000 0.439 0.560

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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