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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3135388
log Bayes Factor = 204.092
Chromosome 6   position 32,413,051  (GRCh37) Explore rs3135388 on Ensembl!
Variant rs3135388 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.001 0.999
K51 Ulcerative colitis
0.999 0.001 0.000
J45.9 Asthma, unspecified
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
G37 Other demyelinating diseases of central nervous system
0.997 0.003 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.996 0.004 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.004 0.996
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.005 0.995
K70-K77 Diseases of liver
0.000 0.006 0.994
E14.3 With ophthalmic complications
0.000 0.006 0.994
Chapter IX Diseases of the circulatory system
0.000 0.007 0.993
I10-I15 Hypertensive diseases
0.000 0.007 0.993
J33 Nasal polyp
0.000 0.007 0.993
J33.9 Nasal polyp, unspecified
0.000 0.007 0.993
I20-I25 Ischaemic heart diseases
0.000 0.009 0.991
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.009 0.991
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.009 0.991
J45 Asthma
0.000 0.009 0.991
K51.3 Ulcerative (chronic) rectosigmoiditis
0.991 0.009 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.011 0.989
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.012 0.988
Chapter X Diseases of the respiratory system
0.000 0.012 0.988
E70-E90 Metabolic disorders
0.000 0.012 0.988
I10 Essential (primary) hypertension
0.000 0.013 0.987
H43-H45 Disorders of vitreous body and globe
0.000 0.014 0.986
H40-H42 Glaucoma
0.000 0.016 0.984
H43 Disorders of vitreous body
0.000 0.019 0.981
E05.9 Thyrotoxicosis, unspecified
0.000 0.020 0.980
K74 Fibrosis and cirrhosis of liver
0.000 0.022 0.978
E10.5 With peripheral circulatory complications
0.000 0.023 0.977
E11.3 With ophthalmic complications
0.000 0.026 0.974
H40 Glaucoma
0.000 0.026 0.974
J30-J39 Other diseases of upper respiratory tract
0.000 0.027 0.973
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.028 0.972
I22 Subsequent myocardial infarction
0.000 0.029 0.971
H40.9 Glaucoma, unspecified
0.000 0.029 0.971
L40-L45 Papulosquamous disorders
0.000 0.034 0.966
K51.8 Other ulcerative colitis
0.965 0.035 0.000
L43 Lichen planus
0.000 0.037 0.963
L40 Psoriasis
0.000 0.038 0.962
J33.8 Other polyp of sinus
0.000 0.038 0.962
E11.1 With ketoacidosis
0.000 0.039 0.961
L43.9 Lichen planus, unspecified
0.000 0.041 0.959
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.041 0.959
E06 Thyroiditis
0.000 0.043 0.957
I20 Angina pectoris
0.000 0.046 0.954
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.046 0.954
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.049 0.951
I12 Hypertensive renal disease
0.000 0.049 0.951
L40.5 Arthropathic psoriasis
0.000 0.050 0.950
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.050 0.950
H43.3 Other vitreous opacities
0.000 0.052 0.948
K74.3 Primary biliary cirrhosis
0.000 0.053 0.947
H43.8 Other disorders of vitreous body
0.000 0.056 0.944
E10.2 With renal complications
0.000 0.057 0.943
K55-K64 Other diseases of intestines
0.000 0.057 0.943
J33.0 Polyp of nasal cavity
0.000 0.063 0.937
K50-K52 Noninfective enteritis and colitis
0.016 0.063 0.921
K60 Fissure and fistula of anal and rectal regions
0.000 0.067 0.933
M70-M79 Other soft tissue disorders
0.000 0.070 0.930
E06.3 Autoimmune thyroiditis
0.000 0.071 0.929
K72 Hepatic failure, not elsewhere classified
0.000 0.083 0.917
E11.2 With renal complications
0.000 0.085 0.915
E13 Other specified diabetes mellitus
0.000 0.086 0.914
H34 Retinal vascular occlusions
0.000 0.086 0.914
Chapter VIII Diseases of the ear and mastoid process
0.000 0.087 0.913
J46 Status asthmaticus
0.000 0.087 0.913
E07 Other disorders of thyroid
0.000 0.097 0.903
H60-H62 Diseases of external ear
0.000 0.098 0.902
E11.5 With peripheral circulatory complications
0.000 0.102 0.898
K60.2 Anal fissure, unspecified
0.000 0.104 0.896
M75 Shoulder lesions
0.000 0.105 0.895
H61 Other disorders of external ear
0.000 0.106 0.894
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.107 0.893
I12.9 Hypertensive renal disease without renal failure
0.000 0.107 0.893
K58 Irritable bowel syndrome
0.000 0.108 0.892
I20.1 Angina pectoris with documented spasm
0.000 0.109 0.891
M06.0 Seronegative rheumatoid arthritis
0.000 0.109 0.891
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.111 0.889
K51.2 Ulcerative (chronic) proctitis
0.882 0.118 0.000
H25-H28 Disorders of lens
0.000 0.118 0.882
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.124 0.876
K60.0 Acute anal fissure
0.000 0.125 0.875
K50 Crohn's disease [regional enteritis]
0.001 0.126 0.873
H61.0 Perichondritis of external ear
0.000 0.126 0.874
M75.0 Adhesive capsulitis of shoulder
0.000 0.128 0.872
I20.9 Angina pectoris, unspecified
0.000 0.129 0.871
M77 Other enthesopathies
0.000 0.134 0.866
L40.9 Psoriasis, unspecified
0.000 0.135 0.865
I15 Secondary hypertension
0.000 0.141 0.859
E03.8 Other specified hypothyroidism
0.000 0.142 0.858
M77.1 Lateral epicondylitis
0.000 0.143 0.856
K60.5 Anorectal fistula
0.000 0.147 0.853
E13.9 Without complications
0.000 0.147 0.853
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.150 0.850
H40.1 Primary open-angle glaucoma
0.000 0.151 0.849
E11.6 With other specified complications
0.000 0.151 0.849
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.153 0.847
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.153 0.846
E07.9 Disorder of thyroid, unspecified
0.000 0.154 0.846
K75 Other inflammatory liver diseases
0.000 0.154 0.846
K74.6 Other and unspecified cirrhosis of liver
0.000 0.156 0.844
M06.4 Inflammatory polyarthropathy
0.000 0.161 0.839
I20.0 Unstable angina
0.000 0.162 0.838
M65-M68 Disorders of synovium and tendon
0.000 0.166 0.834
J86 Pyothorax
0.000 0.169 0.831
K55 Vascular disorders of intestine
0.000 0.170 0.830
K72.9 Hepatic failure, unspecified
0.000 0.171 0.829
K73 Chronic hepatitis, not elsewhere classified
0.000 0.174 0.826
H27 Other disorders of lens
0.000 0.180 0.820
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.180 0.820
I24 Other acute ischaemic heart diseases
0.000 0.180 0.820
K74.5 Biliary cirrhosis, unspecified
0.000 0.184 0.816
K51.4 Pseudopolyposis of colon
0.814 0.185 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.186 0.814
J43 Emphysema
0.000 0.190 0.810
M06.3 Rheumatoid nodule
0.000 0.194 0.806
M75.2 Bicipital tendinitis
0.000 0.196 0.804
H40.5 Glaucoma secondary to other eye disorders
0.000 0.197 0.803
K63 Other diseases of intestine
0.000 0.198 0.802
H34.2 Other retinal artery occlusions
0.000 0.202 0.798
K50.8 Other Crohn's disease
0.000 0.203 0.797
E40-E46 Malnutrition
0.000 0.204 0.796
M07 Psoriatic and enteropathic arthropathies
0.000 0.205 0.794
G37.8 Other specified demyelinating diseases of central nervous system
0.794 0.206 0.000
K75.4 Autoimmune hepatitis
0.000 0.206 0.794
E88 Other metabolic disorders
0.000 0.206 0.794
K51.5 Mucosal proctocolitis
0.792 0.208 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.211 0.789
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.214 0.786
E16.1 Other hypoglycaemia
0.000 0.219 0.781
J44 Other chronic obstructive pulmonary disease
0.000 0.220 0.780
M45-M49 Spondylopathies
0.000 0.220 0.780
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.776 0.224 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.225 0.775
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.225 0.774
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.226 0.774
J37 Chronic laryngitis and laryngotracheitis
0.000 0.226 0.774
I25 Chronic ischaemic heart disease
0.000 0.226 0.774
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.227 0.773
H25 Senile cataract
0.000 0.227 0.773
K63.9 Disease of intestine, unspecified
0.000 0.228 0.772
E78.2 Mixed hyperlipidaemia
0.000 0.228 0.772
E74 Other disorders of carbohydrate metabolism
0.000 0.230 0.770
K50.1 Crohn's disease of large intestine
0.000 0.231 0.769
L43.8 Other lichen planus
0.000 0.232 0.768
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.234 0.766
H61.8 Other specified disorders of external ear
0.000 0.235 0.765
M45 Ankylosing spondylitis
0.000 0.235 0.765
H25.1 Senile nuclear cataract
0.000 0.236 0.764
I15.1 Hypertension secondary to other renal disorders
0.000 0.237 0.763
M65 Synovitis and tenosynovitis
0.000 0.238 0.762
H61.1 Non-infective disorders of pinna
0.000 0.241 0.759
I23 Certain current complications following acute myocardial infarction
0.000 0.242 0.758
M75.3 Calcific tendinitis of shoulder
0.000 0.242 0.758
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.243 0.757
E78.5 Hyperlipidaemia, unspecified
0.000 0.243 0.757
K72.0 Acute and subacute hepatic failure
0.000 0.247 0.753
J32 Chronic sinusitis
0.000 0.250 0.750
J86.9 Pyothorax without fistula
0.000 0.253 0.747
H34.8 Other retinal vascular occlusions
0.000 0.253 0.747
K55.2 Angiodysplasia of colon
0.000 0.255 0.745
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.255 0.745
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.260 0.740
H43.2 Crystalline deposits in vitreous body
0.000 0.261 0.739
K90.9 Intestinal malabsorption, unspecified
0.000 0.265 0.734
K51.0 Ulcerative (chronic) enterocolitis
0.733 0.267 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.268 0.732
L40.8 Other psoriasis
0.000 0.270 0.730
M11 Other crystal arthropathies
0.000 0.271 0.729
E11.8 With unspecified complications
0.000 0.272 0.728
H43.9 Disorder of vitreous body, unspecified
0.000 0.278 0.722
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.280 0.720
L40.0 Psoriasis vulgaris
0.000 0.280 0.720
K63.3 Ulcer of intestine
0.000 0.281 0.719
H40.4 Glaucoma secondary to eye inflammation
0.000 0.282 0.718
I25.5 Ischaemic cardiomyopathy
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.716 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.284 0.715
G36 Other acute disseminated demyelination
0.715 0.285 0.000
G37.5 Concentric sclerosis [Balo]
0.714 0.285 0.000
G37.4 Subacute necrotising myelitis
0.714 0.285 0.000
G37.2 Central pontine myelinolysis
0.714 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.285 0.000
G37.0 Diffuse sclerosis
0.714 0.285 0.000
H34.1 Central retinal artery occlusion
0.000 0.286 0.714
H27.0 Aphakia
0.000 0.286 0.714
H30 Chorioretinal inflammation
0.000 0.287 0.713
K77 Liver disorders in diseases classified elsewhere
0.000 0.287 0.713
K71 Toxic liver disease
0.000 0.287 0.713
H61.3 Acquired stenosis of external ear canal
0.000 0.288 0.712
I00-I02 Acute rheumatic fever
0.000 0.288 0.712
I13 Hypertensive heart and renal disease
0.000 0.288 0.712
J33.1 Polypoid sinus degeneration
0.000 0.288 0.712
E78.6 Lipoprotein deficiency
0.000 0.289 0.711
E78.3 Hyperchylomicronaemia
0.000 0.289 0.711
J45.8 Mixed asthma
0.000 0.289 0.710
J45.1 Nonallergic asthma
0.000 0.289 0.710
H43.1 Vitreous haemorrhage
0.000 0.290 0.710
K55.8 Other vascular disorders of intestine
0.000 0.290 0.710
E05.5 Thyroid crisis or storm
0.000 0.291 0.709
E05.4 Thyrotoxicosis factitia
0.000 0.291 0.709
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.291 0.709
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.291 0.709
J86.0 Pyothorax with fistula
0.000 0.291 0.709
E77 Disorders of glycoprotein metabolism
0.000 0.292 0.708
E76 Disorders of glycosaminoglycan metabolism
0.000 0.292 0.708
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.292 0.708
E72 Other disorders of amino-acid metabolism
0.000 0.292 0.708
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.292 0.708
E70 Disorders of aromatic amino-acid metabolism
0.000 0.292 0.708
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.292 0.708
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.293 0.707
H42 Glaucoma in diseases classified elsewhere
0.000 0.294 0.706
H43.0 Vitreous prolapse
0.000 0.297 0.703
E11.0 With coma
0.000 0.298 0.701
K74.4 Secondary biliary cirrhosis
0.000 0.299 0.701
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.299 0.701
K74.1 Hepatic sclerosis
0.000 0.299 0.701
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.300 0.700
I11 Hypertensive heart disease
0.000 0.301 0.699
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.302 0.698
H40.6 Glaucoma secondary to drugs
0.000 0.302 0.698
H40.3 Glaucoma secondary to eye trauma
0.000 0.302 0.698
H27.8 Other specified disorders of lens
0.000 0.302 0.697
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.304 0.696
M75.4 Impingement syndrome of shoulder
0.000 0.304 0.696
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.304 0.696
L44 Other papulosquamous disorders
0.000 0.307 0.693
L41 Parapsoriasis
0.000 0.307 0.693
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.307 0.693
L43.3 Subacute (active) lichen planus
0.000 0.310 0.690
L43.2 Lichenoid drug reaction
0.000 0.310 0.690
L43.1 Bullous lichen planus
0.000 0.310 0.690
L43.0 Hypertrophic lichen planus
0.000 0.310 0.690
L40.4 Guttate psoriasis
0.000 0.310 0.690
L40.3 Pustulosis palmaris et plantaris
0.000 0.310 0.690
L40.2 Acrodermatitis continua
0.000 0.310 0.690
L40.1 Generalised pustular psoriasis
0.000 0.310 0.690
E06.5 Other chronic thyroiditis
0.000 0.314 0.686
E06.4 Drug-induced thyroiditis
0.000 0.314 0.686
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.314 0.686
E06.1 Subacute thyroiditis
0.000 0.314 0.686
E06.0 Acute thyroiditis
0.000 0.314 0.686
J41 Simple and mucopurulent chronic bronchitis
0.000 0.314 0.686
E11.4 With neurological complications
0.000 0.316 0.684
K52 Other non-infective gastro-enteritis and colitis
0.003 0.316 0.681
M12 Other specific arthropathies
0.000 0.317 0.683
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.317 0.683
K73.9 Chronic hepatitis, unspecified
0.000 0.319 0.681
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.320 0.680
H60 Otitis externa
0.000 0.321 0.679
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.321 0.678
E05.8 Other thyrotoxicosis
0.000 0.322 0.678
M76 Enthesopathies of lower limb, excluding foot
0.000 0.322 0.678
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.324 0.676
K63.4 Enteroptosis
0.000 0.332 0.668
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.333 0.667
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.335 0.665
E06.9 Thyroiditis, unspecified
0.000 0.337 0.663
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.337 0.663
K50.0 Crohn's disease of small intestine
0.000 0.338 0.661
M14.6 Neuropathic arthropathy
0.000 0.338 0.662
E84 Cystic fibrosis
0.000 0.342 0.658
K72.1 Chronic hepatic failure
0.000 0.343 0.657
M72 Fibroblastic disorders
0.000 0.343 0.657
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.344 0.656
E13.8 With unspecified complications
0.000 0.344 0.655
E13.7 With multiple complications
0.000 0.344 0.655
E13.6 With other specified complications
0.000 0.344 0.655
E13.5 With peripheral circulatory complications
0.000 0.344 0.655
E13.4 With neurological complications
0.000 0.344 0.655
E13.3 With ophthalmic complications
0.000 0.344 0.655
E13.2 With renal complications
0.000 0.344 0.655
E13.1 With ketoacidosis
0.000 0.344 0.655
E13.0 With coma
0.000 0.344 0.655
H34.0 Transient retinal artery occlusion
0.000 0.345 0.655
M06.34 Rheumatoid nodule (Hand)
0.000 0.348 0.652
E46 Unspecified protein-energy malnutrition
0.000 0.350 0.650
M07.3 Other psoriatic arthropathies
0.000 0.353 0.647
E07.1 Dyshormogenetic goitre
0.000 0.353 0.647
E07.0 Hypersecretion of calcitonin
0.000 0.353 0.647
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.353 0.647
H65-H75 Diseases of middle ear and mastoid
0.000 0.353 0.647
M75.8 Other shoulder lesions
0.000 0.358 0.641
J43.9 Emphysema, unspecified
0.000 0.359 0.641
E78.8 Other disorders of lipoprotein metabolism
0.000 0.359 0.641
J95-J99 Other diseases of the respiratory system
0.000 0.361 0.639
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.361 0.639
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.361 0.639
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.361 0.639
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.361 0.639
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.361 0.639
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.361 0.639
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.361 0.639
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.361 0.639
J43.2 Centrilobular emphysema
0.000 0.363 0.637
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.363 0.637
H34.9 Retinal vascular occlusion, unspecified
0.000 0.363 0.636
H27.1 Dislocation of lens
0.000 0.364 0.636
E79 Disorders of purine and pyrimidine metabolism
0.000 0.364 0.635
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.367 0.633
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.367 0.632
J37.0 Chronic laryngitis
0.000 0.368 0.632
L42 Pityriasis rosea
0.000 0.369 0.631
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.369 0.631
J32.4 Chronic pansinusitis
0.000 0.369 0.631
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.370 0.630
K55.1 Chronic vascular disorders of intestine
0.000 0.373 0.627
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.377 0.622
L10-L14 Bullous disorders
0.000 0.378 0.622
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.379 0.621
M77.3 Calcaneal spur
0.000 0.379 0.621
M77.2 Periarthritis of wrist
0.000 0.379 0.621
M10 Gout
0.000 0.380 0.620
K82 Other diseases of gallbladder
0.000 0.382 0.618
K52.1 Toxic gastro-enteritis and colitis
0.001 0.383 0.616
I15.9 Seconday hypertension, unspecified
0.000 0.384 0.616
I15.8 Other secondary hypertension
0.000 0.384 0.616
I15.2 Hypertension secondary to endocrine disorders
0.000 0.384 0.616
I15.0 Renovascular hypertension
0.000 0.384 0.616
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.386 0.614
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.386 0.614
M77.18 Lateral epicondylitis-Other
0.000 0.386 0.614
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.386 0.614
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.386 0.614
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.386 0.614
M77.14 Lateral epicondylitis-Hand
0.000 0.386 0.614
M77.13 Lateral epicondylitis-Forearm
0.000 0.386 0.614
M77.11 Lateral epicondylitis-Shldr region
0.000 0.386 0.614
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.386 0.614
J85 Abscess of lung and mediastinum
0.000 0.387 0.613
K76 Other diseases of liver
0.000 0.388 0.612
K74.0 Hepatic fibrosis
0.000 0.389 0.611
E88.2 Lipomatosis, not elsewhere classified
0.000 0.389 0.611
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.390 0.610
H61.9 Disorder of external ear, unspecified
0.000 0.391 0.609
I25.2 Old myocardial infarction
0.000 0.392 0.608
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.392 0.608
K75.9 Inflammatory liver disease, unspecified
0.000 0.392 0.607
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.393 0.607
K75.2 Nonspecific reactive hepatitis
0.000 0.393 0.607
K75.1 Phlebitis of portal vein
0.000 0.393 0.607
E73 Lactose intolerance
0.000 0.395 0.605
E83 Disorders of mineral metabolism
0.370 0.395 0.235
K82.8 Other specified diseases of gallbladder
0.000 0.397 0.603
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.398 0.602
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.398 0.602
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.398 0.602
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.398 0.602
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.398 0.602
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.398 0.602
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.398 0.602
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.398 0.602
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.399 0.600
K60.1 Chronic anal fissure
0.000 0.400 0.600
M77.5 Other enthesopathy of foot
0.000 0.401 0.599
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.402 0.598
J31.2 Chronic pharyngitis
0.000 0.403 0.597
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.405 0.595
K60.4 Rectal fistula
0.000 0.406 0.594
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.408 0.592
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.408 0.592
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.408 0.592
M60-M63 Disorders of muscles
0.000 0.408 0.591
I23.8 Other current complications following acute myocardial infarction
0.000 0.409 0.591
H25.9 Senile cataract, unspecified
0.000 0.411 0.589
H27.9 Disorder of lens, unspecified
0.000 0.412 0.588
M91-M94 Chondropathies
0.000 0.413 0.587
E07.8 Other specified disorders of thyroid
0.000 0.414 0.586
K76.8 Other specified diseases of liver
0.000 0.415 0.585
M49 Spondylopathies in diseases classified elsewhere
0.000 0.415 0.585
M71 Other bursopathies
0.000 0.416 0.584
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.416 0.584
K62 Other diseases of anus and rectum
0.000 0.417 0.583
J43.8 Other emphysema
0.000 0.419 0.581
J43.1 Panlobular emphysema
0.000 0.419 0.581
J43.0 MacLeod's syndrome
0.000 0.419 0.581
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.422 0.578
M06.38 Rheumatoid nodule (Other)
0.000 0.422 0.578
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.422 0.578
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.422 0.578
M06.33 Rheumatoid nodule (Forearm)
0.000 0.422 0.578
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.422 0.578
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.422 0.578
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.422 0.578
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.422 0.578
K90.8 Other intestinal malabsorption
0.000 0.423 0.576
M00-M03 Infectious arthropathies
0.000 0.424 0.576
J42 Unspecified chronic bronchitis
0.000 0.425 0.575
M77.0 Medial epicondylitis
0.000 0.427 0.573
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.429 0.571
E45 Retarded development following protein-energy malnutrition
0.000 0.429 0.571
E43 Unspecified severe protein-energy malnutrition
0.000 0.429 0.571
E42 Marasmic kwashiorkor
0.000 0.429 0.571
E41 Nutritional marasmus
0.000 0.429 0.571
E40 Kwashiorkor
0.000 0.429 0.571
H71 Cholesteatoma of middle ear
0.000 0.430 0.570
M07.6 Other enteropathic arthropathies
0.000 0.430 0.570
M07.5 Arthropathy in ulcerative colitis
0.000 0.430 0.570
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.430 0.570
M07.2 Psoriatic spondylitis
0.000 0.430 0.570
M07.1 Arthritis mutilans
0.000 0.430 0.570
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.430 0.570
E88.9 Metabolic disorder, unspecified
0.000 0.431 0.569
E88.8 Other specified metabolic disorders
0.000 0.431 0.569
E88.3 Tumour lysis syndrome
0.000 0.431 0.569
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.431 0.569
J32.9 Chronic sinusitis, unspecified
0.000 0.431 0.569
H35 Other retinal disorders
0.000 0.434 0.566
J32.8 Other chronic sinusitis
0.000 0.435 0.565

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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