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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs31489
log Bayes Factor = 53.5032
Chromosome 5   position 1,342,714  (GRCh37) Explore rs31489 on Ensembl!
Variant rs31489 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.5 Skin of trunk
0.000 0.000 1.000
C44.3 Skin of other and unspecified parts of face
0.000 0.000 1.000
C67.9 Bladder, unspecified
0.000 0.000 1.000
C34 Malignant neoplasm of bronchus and lung
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
C67 Malignant neoplasm of bladder
0.000 0.000 1.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
C34.1 Upper lobe, bronchus or lung
0.000 0.000 1.000
N32.8 Other specified disorders of bladder
0.000 0.000 1.000
C64-C68 Malignant neoplasms of urinary tract
0.000 0.000 1.000
N32 Other disorders of bladder
0.000 0.000 1.000
L72.1 Trichilemmal cyst
0.000 0.000 1.000
C34.9 Bronchus or lung, unspecified
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
0.000 0.000 1.000
N32.0 Bladder-neck obstruction
0.000 0.000 1.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.001 0.999
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.001 0.999
Chapter II Neoplasms
0.000 0.001 0.999
C67.4 Posterior wall of bladder
0.000 0.001 0.999
C44.1 Skin of eyelid, including canthus
0.000 0.002 0.998
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.003 0.997
C34.3 Lower lobe, bronchus or lung
0.000 0.006 0.994
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.000 0.007 0.993
C43 Malignant melanoma of skin
0.991 0.009 0.000
D41.4 Bladder
0.000 0.010 0.990
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.011 0.989
C43.7 Malignant melanoma of lower limb, including hip
0.989 0.011 0.000
C43.5 Malignant melanoma of trunk
0.988 0.012 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.015 0.985
N42 Other disorders of prostate
0.000 0.016 0.984
N42.9 Disorder of prostate, unspecified
0.000 0.017 0.983
L72.0 Epidermal cyst
0.000 0.018 0.982
N40-N51 Diseases of male genital organs
0.000 0.018 0.982
L72 Follicular cysts of skin and subcutaneous tissue
0.000 0.018 0.982
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.020 0.980
C66 Malignant neoplasm of ureter
0.000 0.023 0.977
C67.2 Lateral wall of bladder
0.000 0.029 0.971
N32.9 Bladder disorder, unspecified
0.000 0.048 0.952
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.076 0.924
D47.1 Chronic myeloproliferative disease
0.000 0.080 0.920
C67.6 Ureteric orifice
0.000 0.081 0.919
C67.5 Bladder neck
0.000 0.101 0.899
C44.0 Skin of lip
0.000 0.108 0.892
N42.2 Atrophy of prostate
0.000 0.113 0.887
C43.3 Malignant melanoma of other and unspecified parts of face
0.882 0.118 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.880 0.120 0.000
C34.0 Main bronchus
0.000 0.134 0.866
C34.2 Middle lobe, bronchus or lung
0.000 0.135 0.865
C44.4 Skin of scalp and neck
0.000 0.142 0.858
C43.4 Malignant melanoma of scalp and neck
0.855 0.145 0.000
C67.8 Overlapping lesion of bladder
0.000 0.151 0.849
N41 Inflammatory diseases of prostate
0.000 0.158 0.842
N42.8 Other specified disorders of prostate
0.000 0.166 0.834
N45 Orchitis and epididymitis
0.000 0.170 0.830
N46 Male infertility
0.000 0.182 0.818
D40.0 Prostate
0.000 0.186 0.814
D40.1 Testis
0.000 0.186 0.814
N32.2 Vesical fistula, not elsewhere classified
0.000 0.187 0.813
N32.3 Diverticulum of bladder
0.000 0.187 0.813
N42.0 Calculus of prostate
0.000 0.192 0.808
C37 Malignant neoplasm of thymus
0.000 0.200 0.800
C67.3 Anterior wall of bladder
0.000 0.202 0.798
C43.1 Malignant melanoma of eyelid, including canthus
0.793 0.207 0.000
D47.4 Osteomyelofibrosis
0.000 0.213 0.787
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.221 0.779
D41.2 Ureter
0.000 0.227 0.773
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.231 0.769
C65 Malignant neoplasm of renal pelvis
0.000 0.244 0.756
C43.9 Malignant melanoma of skin, unspecified
0.751 0.249 0.000
C31 Malignant neoplasm of accessory sinuses
0.000 0.252 0.748
D41.0 Kidney
0.000 0.257 0.743
N41.1 Chronic prostatitis
0.000 0.260 0.740
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.267 0.733
C44.2 Skin of ear and external auricular canal
0.000 0.276 0.724
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
C67.7 Urachus
0.000 0.283 0.717
N32.4 Rupture of bladder, nontraumatic
0.000 0.283 0.717
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.284 0.716
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.285 0.715
D41.9 Urinary organ, unspecified
0.000 0.288 0.712
D41.7 Other urinary organs
0.000 0.288 0.712
D41.3 Urethra
0.000 0.288 0.712
D41.1 Renal pelvis
0.000 0.288 0.712
C43.8 Overlapping malignant melanoma of skin
0.710 0.290 0.000
C43.0 Malignant melanoma of lip
0.710 0.290 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.291 0.709
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.291 0.709
C34.8 Overlapping lesion of bronchus and lung
0.000 0.295 0.705
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.295 0.705
N41.0 Acute prostatitis
0.000 0.304 0.696
C43.6 Malignant melanoma of upper limb, including shoulder
0.695 0.305 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.307 0.693
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.315 0.685
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.323 0.676
D43.0 Brain, supratentorial
0.000 0.332 0.668
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.333 0.667
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.334 0.666
D40.9 Male genital organ, unspecified
0.000 0.337 0.662
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.000 0.340 0.660
D39.0 Uterus
0.000 0.344 0.656
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.345 0.655
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.356 0.644
N42.3 Dysplasia of prostate
0.000 0.357 0.643
C67.1 Dome of bladder
0.000 0.358 0.642
D40.7 Other male genital organs
0.000 0.370 0.630
D43.4 Spinal cord
0.000 0.371 0.629
C67.0 Trigone of bladder
0.000 0.374 0.626
L72.2 Steatocystoma multiplex
0.000 0.380 0.620
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.384 0.616
C33 Malignant neoplasm of trachea
0.000 0.389 0.611
N41.2 Abscess of prostate
0.000 0.396 0.604
N41.3 Prostatocystitis
0.000 0.396 0.604
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.399 0.601
D00-D09 In situ neoplasms
0.000 0.421 0.579
D43.1 Brain, infratentorial
0.000 0.422 0.578
N49.2 Inflammatory disorders of scrotum
0.000 0.427 0.573
C31.0 Maxillary sinus
0.000 0.433 0.567
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.437 0.563
D43.9 Central nervous system, unspecified
0.000 0.441 0.559
D43.7 Other parts of central nervous system
0.000 0.441 0.559
D43.3 Cranial nerves
0.000 0.441 0.559
D39.9 Female genital organ, unspecified
0.000 0.449 0.551
D39.2 Placenta
0.000 0.449 0.551
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.450 0.550
N44 Torsion of testis
0.000 0.452 0.548
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.455 0.545
C68.0 Urethra
0.000 0.463 0.537
C31.9 Accessory sinus, unspecified
0.000 0.464 0.536
C31.8 Overlapping lesion of accessory sinuses
0.000 0.464 0.536
C31.3 Sphenoidal sinus
0.000 0.464 0.536
C31.2 Frontal sinus
0.000 0.464 0.536
C31.1 Ethmoidal sinus
0.000 0.464 0.536
C68.9 Urinary organ, unspecified
0.000 0.470 0.530
D39.7 Other female genital organs
0.000 0.470 0.530
C68.8 Overlapping lesion of urinary organs
0.000 0.474 0.525
C68.1 Paraurethral glands
0.000 0.474 0.525
N41.8 Other inflammatory diseases of prostate
0.000 0.481 0.518
C39.9 Ill-defined sites within the respiratory system
0.000 0.486 0.514
C39.8 Overlapping lesion of respiratory and intrathoracic organs
0.000 0.486 0.514
C39.0 Upper respiratory tract, part unspecified
0.000 0.486 0.514
D42.9 Meninges, unspecified
0.000 0.487 0.512
D42.1 Spinal meninges
0.000 0.487 0.512
D42.0 Cerebral meninges
0.000 0.487 0.512
N42.1 Congestion and haemorrhage of prostate
0.000 0.488 0.511
D07.5 Prostate
0.000 0.493 0.507
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.495 0.505
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.495 0.505
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.495 0.505
C32 Malignant neoplasm of larynx
0.000 0.506 0.494
C40-C41 Malignant neoplasms of bone and articular cartilage
0.001 0.514 0.485
D39.1 Ovary
0.000 0.517 0.483
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.519 0.481
D04 Carcinoma in situ of skin
0.000 0.521 0.479
N13 Obstructive and reflux uropathy
0.000 0.521 0.479
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.000 0.522 0.478
C30.1 Middle ear
0.000 0.522 0.478
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.522 0.478
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.522 0.478
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.522 0.478
N10-N16 Renal tubulo-interstitial diseases
0.000 0.526 0.474
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.527 0.473
Chapter XIV Diseases of the genitourinary system
0.000 0.533 0.467
D07.4 Penis
0.000 0.538 0.462
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.000 0.538 0.462
C38.3 Mediastinum, part unspecified
0.000 0.538 0.462
C38.2 Posterior mediastinum
0.000 0.538 0.462
C38.1 Anterior mediastinum
0.000 0.538 0.462
C38.0 Heart
0.000 0.538 0.462
N30-N39 Other diseases of urinary system
0.000 0.539 0.461
D09 Carcinoma in situ of other and unspecified sites
0.000 0.541 0.459
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.555 0.445
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.557 0.443
D38.1 Trachea, bronchus and lung
0.000 0.559 0.441
N51.2 Balanitis in diseases classified elsewhere
0.000 0.560 0.440
C21.1 Anal canal
0.000 0.564 0.436
C21 Malignant neoplasm of anus and anal canal
0.000 0.566 0.434
D38.6 Respiratory organ, unspecified
0.000 0.569 0.431
D38.4 Thymus
0.000 0.569 0.431
D38.3 Mediastinum
0.000 0.569 0.431
D38.2 Pleura
0.000 0.569 0.431
C30.0 Nasal cavity
0.000 0.571 0.428
D04.6 Skin of upper limb, including shoulder
0.000 0.578 0.422
C50-C50 Malignant neoplasm of breast
0.000 0.582 0.418
C21.0 Anus, unspecified
0.000 0.583 0.417
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.000 0.583 0.417
C15-C26 Malignant neoplasms of digestive organs
0.000 0.584 0.416
D04.5 Skin of trunk
0.000 0.584 0.416
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.586 0.414
N13.4 Hydroureter
0.000 0.587 0.413
D45 Polycythaemia vera
0.000 0.591 0.408
C25.9 Pancreas, unspecified
0.405 0.595 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.595 0.405
N13.3 Other and unspecified hydronephrosis
0.000 0.595 0.405
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.601 0.399
D38.0 Larynx
0.000 0.604 0.396
D07.6 Other and unspecified male genital organs
0.000 0.609 0.391
D07.3 Other and unspecified female genital organs
0.000 0.609 0.391
D07.0 Endometrium
0.000 0.609 0.391
C38.4 Pleura
0.000 0.610 0.390
C25 Malignant neoplasm of pancreas
0.369 0.610 0.021
D04.1 Skin of eyelid, including canthus
0.000 0.611 0.389
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.001 0.613 0.386
D09.0 Bladder
0.000 0.618 0.382
N13.5 Kinking and stricture of ureter without hydronephrosis
0.000 0.619 0.381
D07.2 Vagina
0.000 0.621 0.379
N14.1 Nephropathy induced by other drugs, medicaments and biological substances
0.000 0.623 0.377
N11 Chronic tubulo-interstitial nephritis
0.000 0.624 0.376
D07.1 Vulva
0.000 0.624 0.376
N48 Other disorders of penis
0.000 0.626 0.374
D44.1 Adrenal gland
0.000 0.631 0.369
N13.6 Pyonephrosis
0.000 0.632 0.368
C25.0 Head of pancreas
0.361 0.637 0.002
D44.6 Carotid body
0.000 0.638 0.362
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.000 0.639 0.361
D01.3 Anus and anal canal
0.000 0.640 0.360
C32.8 Overlapping lesion of larynx
0.000 0.646 0.354
C32.3 Laryngeal cartilage
0.000 0.646 0.354
C32.2 Subglottis
0.000 0.646 0.354
N48.8 Other specified disorders of penis
0.000 0.646 0.354
D44.4 Craniopharyngeal duct
0.000 0.646 0.354
N13.7 Vesicoureteral-reflux-associated uropathy
0.000 0.647 0.353
D38.5 Other respiratory organs
0.000 0.648 0.352
D46 Myelodysplastic syndromes
0.000 0.649 0.351
D09.1 Other and unspecified urinary organs
0.000 0.650 0.350
D04.2 Skin of ear and external auricular canal
0.000 0.651 0.349
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.001 0.652 0.348
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.653 0.347
D44.5 Pineal gland
0.000 0.655 0.345
D44.2 Parathyroid gland
0.000 0.655 0.345
D04.8 Skin of other sites
0.000 0.656 0.344
D04.0 Skin of lip
0.000 0.656 0.344
D01.2 Rectum
0.000 0.658 0.342
D47.2 Monoclonal gammopathy
0.000 0.659 0.340
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.659 0.340
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.000 0.660 0.340
N13.9 Obstructive and reflux uropathy, unspecified
0.000 0.663 0.337
N00-N08 Glomerular diseases
0.000 0.666 0.334
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.001 0.668 0.331
N37 Urethral disorders in diseases classified elsewhere
0.000 0.669 0.331
N33 Bladder disorders in diseases classified elsewhere
0.000 0.669 0.331
D44.7 Aortic body and other paraganglia
0.000 0.670 0.329
D00.1 Oesophagus
0.000 0.670 0.330
D09.7 Carcinoma in situ of other specified sites
0.000 0.671 0.329
D09.3 Thyroid and other endocrine glands
0.000 0.671 0.329
D09.2 Eye
0.000 0.671 0.329
N10 Acute tubulo-interstitial nephritis
0.000 0.672 0.328
C23 Malignant neoplasm of gallbladder
0.000 0.675 0.325
D04.9 Skin, unspecified
0.000 0.677 0.323
D01.9 Digestive organ, unspecified
0.000 0.681 0.319
D01.7 Other specified digestive organs
0.000 0.681 0.319
D01.5 Liver, gallbladder and bile ducts
0.000 0.681 0.319
D01.4 Other and unspecified parts of intestine
0.000 0.681 0.319
D01.1 Rectosigmoid junction
0.000 0.681 0.319
D04.7 Skin of lower limb, including hip
0.000 0.681 0.319
C32.9 Larynx, unspecified
0.000 0.683 0.317
C21.2 Cloacogenic zone
0.000 0.689 0.311
D44.3 Pituitary gland
0.000 0.689 0.311
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.000 0.691 0.309
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.000 0.691 0.309
C32.0 Glottis
0.000 0.693 0.307
N32.1 Vesicointestinal fistula
0.001 0.693 0.306
C17 Malignant neoplasm of small intestine
0.000 0.698 0.301
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.000 0.699 0.301
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.001 0.700 0.299
N14.4 Toxic nephropathy, not elsewhere classified
0.000 0.701 0.299
N14.3 Nephropathy induced by heavy metals
0.000 0.701 0.299
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance
0.000 0.701 0.299
N14.0 Analgesic nephropathy
0.000 0.701 0.299
D00.2 Stomach
0.000 0.703 0.297
D44.8 Pluriglandular involvement
0.000 0.705 0.294
N05 Unspecified nephritic syndrome
0.000 0.705 0.295
N04 Nephrotic syndrome
0.000 0.706 0.294
C25.3 Pancreatic duct
0.275 0.711 0.014
C45 Mesothelioma
0.000 0.713 0.287
D09.9 Carcinoma in situ, unspecified
0.000 0.713 0.287
C46 Kaposi's sarcoma
0.000 0.713 0.286
C70 Malignant neoplasm of meninges
0.000 0.713 0.286
D43.2 Brain, unspecified
0.001 0.715 0.284
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.715 0.284
D48.2 Peripheral nerves and autonomic nervous system
0.000 0.716 0.284
N48.1 Balanoposthitis
0.000 0.717 0.283
D44.9 Endocrine gland, unspecified
0.000 0.717 0.282
D44.0 Thyroid gland
0.000 0.718 0.282
C60-C63 Malignant neoplasms of male genital organs
0.001 0.720 0.279
C25.8 Overlapping lesion of pancreas
0.264 0.720 0.015
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.000 0.720 0.279
C32.1 Supraglottis
0.000 0.720 0.279
N15 Other renal tubulo-interstitial diseases
0.000 0.722 0.278
C25.1 Body of pancreas
0.264 0.722 0.013
C25.4 Endocrine pancreas
0.261 0.724 0.015
D48.0 Bone and articular cartilage
0.000 0.724 0.276
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.724 0.275
N13.8 Other obstructive and reflux uropathy
0.000 0.725 0.275
C25.7 Other parts of pancreas
0.258 0.727 0.015
D06 Carcinoma in situ of cervix uteri
0.000 0.727 0.273
C17.0 Duodenum
0.000 0.727 0.272
D01.0 Colon
0.000 0.729 0.271
D04.4 Skin of scalp and neck
0.000 0.729 0.271
N11.8 Other chronic tubulo-interstitial nephritis
0.000 0.730 0.270
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.733 0.267
N43 Hydrocele and spermatocele
0.000 0.734 0.265
D46.1 Refractory anaemia with sideroblasts
0.000 0.738 0.262
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.000 0.739 0.260
N05.1 Focal and segmental glomerular lesions
0.000 0.740 0.260
N34 Urethritis and urethral syndrome
0.000 0.740 0.260
N11.1 Chronic obstructive pyelonephritis
0.000 0.744 0.255
C72.0 Spinal cord
0.000 0.746 0.254
N04.9 Unspecified
0.000 0.746 0.254
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.000 0.747 0.253
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.000 0.748 0.251
D46.5 Refractory anaemia with multi-lineage dysplasia
0.000 0.748 0.251
D46.3 Refractory anaemia with excess of blasts with transformation
0.000 0.748 0.251
D46.0 Refractory anaemia without sideroblasts, so stated
0.000 0.748 0.251
N48.3 Priapism
0.000 0.749 0.251
N00 Acute nephritic syndrome
0.000 0.750 0.250
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)
0.001 0.750 0.249
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)
0.001 0.750 0.249
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)
0.001 0.750 0.249
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)
0.001 0.750 0.249
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)
0.001 0.750 0.249
D00.0 Lip, oral cavity and pharynx
0.000 0.751 0.249
N48.4 Impotence of organic origin
0.000 0.751 0.249
D48.3 Retroperitoneum
0.000 0.751 0.249
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.000 0.752 0.248
N99-N99 Other disorders of the genitourinary system
0.000 0.753 0.246
D02.4 Respiratory system, unspecified
0.000 0.756 0.244
D02.3 Other parts of respiratory system
0.000 0.756 0.244
D02.2 Bronchus and lung
0.000 0.756 0.244
D02.1 Trachea
0.000 0.756 0.244
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere
0.000 0.756 0.244
N16.5 Renal tubulo-interstitial disorders in transplant rejection
0.000 0.756 0.244
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders
0.000 0.756 0.244
N16.3 Renal tubulo-interstitial disorders in metabolic diseases
0.000 0.756 0.244
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism
0.000 0.756 0.244
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases
0.000 0.756 0.244
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere
0.000 0.756 0.244
C45.0 Mesothelioma of pleura
0.000 0.757 0.243
C25.2 Tail of pancreas
0.227 0.758 0.015
D48.4 Peritoneum
0.000 0.758 0.242
D46.7 Other myelodysplastic syndromes
0.000 0.759 0.241
N48.2 Other inflammatory disorders of penis
0.000 0.759 0.241
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.760 0.240
N06 Isolated proteinuria with specified morphological lesion
0.000 0.760 0.240
N01 Rapidly progressive nephritic syndrome
0.000 0.760 0.240
N05.2 Diffuse membranous glomerulonephritis
0.000 0.761 0.238
C74 Malignant neoplasm of adrenal gland
0.001 0.762 0.237
N33.8 Bladder disorders in other diseases classified elsewhere
0.000 0.762 0.237
N33.0 Tuberculous cystitis
0.000 0.762 0.237
N37.8 Other urethral disorders in diseases classified elsewhere
0.000 0.762 0.237
N37.0 Urethritis in diseases classified elsewhere
0.000 0.762 0.237
N04.0 Minor glomerular abnormality
0.000 0.763 0.237
D46.2 Refractory anaemia with excess of blasts
0.000 0.764 0.235
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.000 0.765 0.234
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.767 0.233
N05.8 Other
0.000 0.777 0.223
C72.9 Central nervous system, unspecified
0.000 0.778 0.222
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.000 0.778 0.222
C72.5 Other and unspecified cranial nerves
0.000 0.778 0.222
C72.4 Acoustic nerve
0.000 0.778 0.222
C72.3 Optic nerve
0.000 0.778 0.222
C72.2 Olfactory nerve
0.000 0.778 0.222
C72.1 Cauda equina
0.000 0.778 0.222
N48.5 Ulcer of penis
0.000 0.780 0.220
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.781 0.219
C17.8 Overlapping lesion of small intestine
0.000 0.783 0.216
C17.3 Meckel's diverticulum
0.000 0.783 0.216
N20-N23 Urolithiasis
0.000 0.784 0.216
C40.9 Bone and articular cartilage of limb, unspecified
0.001 0.784 0.215
C40.8 Overlapping lesion of bone and articular cartilage of limbs
0.001 0.784 0.215
C40.3 Short bones of lower limb
0.001 0.784 0.215
C40.1 Short bones of upper limb
0.001 0.784 0.215
C40.0 Scapula and long bones of upper limb
0.001 0.784 0.215
D04.3 Skin of other and unspecified parts of face
0.000 0.785 0.215
C70.0 Cerebral meninges
0.000 0.785 0.214
N35 Urethral stricture
0.000 0.786 0.214
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.001 0.787 0.212
N02 Recurrent and persistent haematuria
0.000 0.788 0.212
N05.6 Dense deposit disease
0.000 0.789 0.211
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.789 0.211
N05.0 Minor glomerular abnormality
0.000 0.789 0.211
N04.8 Other
0.000 0.789 0.211
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.789 0.211
N04.6 Dense deposit disease
0.000 0.789 0.211
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.789 0.211
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.789 0.211
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.789 0.211
N04.2 Diffuse membranous glomerulonephritis
0.000 0.789 0.211
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.789 0.211
C17.1 Jejunum
0.000 0.789 0.210
N04.1 Focal and segmental glomerular lesions
0.000 0.792 0.208
C45.2 Mesothelioma of pericardium
0.000 0.794 0.206
C45.1 Mesothelioma of peritoneum
0.000 0.794 0.206
C46.9 Kaposi's sarcoma, unspecified
0.000 0.794 0.205
C46.8 Kaposi's sarcoma of multiple organs
0.000 0.794 0.205
C46.7 Kaposi's sarcoma of other sites
0.000 0.794 0.205
C46.3 Kaposi's sarcoma of lymph nodes
0.000 0.794 0.205
C46.2 Kaposi's sarcoma of palate
0.000 0.794 0.205
C46.1 Kaposi's sarcoma of soft tissue
0.000 0.794 0.205
C46.0 Kaposi's sarcoma of skin
0.000 0.794 0.205
C70.9 Meninges, unspecified
0.000 0.794 0.205
C70.1 Spinal meninges
0.000 0.794 0.205
C26.9 Ill-defined sites within the digestive system
0.000 0.795 0.205
N48.0 Leukoplakia of penis
0.000 0.795 0.204
C26.8 Overlapping lesion of digestive system
0.000 0.796 0.204
C26.1 Spleen
0.000 0.796 0.204
D46.4 Refractory anaemia, unspecified
0.001 0.796 0.203
C24.1 Ampulla of Vater
0.000 0.797 0.203
N15.8 Other specified renal tubulo-interstitial diseases
0.000 0.800 0.200
N15.0 Balkan nephropathy
0.000 0.800 0.200
C24.9 Biliary tract, unspecified
0.000 0.802 0.198
C24.8 Overlapping lesion of biliary tract
0.000 0.802 0.197
N34.1 Nonspecific urethritis
0.000 0.803 0.196
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.804 0.196
D06.7 Other parts of cervix
0.000 0.804 0.196
N15.1 Renal and perinephric abscess
0.000 0.806 0.194
D48.6 Breast
0.000 0.806 0.194
D06.1 Exocervix
0.000 0.807 0.193
N43.0 Encysted hydrocele
0.000 0.809 0.190
N00.9 Unspecified
0.000 0.810 0.190
C63 Malignant neoplasm of other and unspecified male genital organs
0.001 0.810 0.189
C26.0 Intestinal tract, part unspecified
0.000 0.811 0.188
N20 Calculus of kidney and ureter
0.000 0.812 0.188
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.000 0.813 0.187
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.000 0.813 0.187
C47.6 Peripheral nerves of trunk, unspecified
0.000 0.813 0.187
C47.5 Peripheral nerves of pelvis
0.000 0.813 0.187
C47.4 Peripheral nerves of abdomen
0.000 0.813 0.187
C47.3 Peripheral nerves of thorax
0.000 0.813 0.187
C47.2 Peripheral nerves of lower limb, including hip
0.000 0.813 0.187
C47.0 Peripheral nerves of head, face and neck
0.000 0.813 0.187
L60-L75 Disorders of skin appendages
0.000 0.813 0.187
N02.2 Diffuse membranous glomerulonephritis
0.000 0.814 0.186
N48.9 Disorder of penis, unspecified
0.000 0.818 0.182
N20.0 Calculus of kidney
0.000 0.819 0.181
C48.2 Peritoneum, unspecified
0.000 0.820 0.180
N00.8 Other
0.000 0.820 0.179
N00.7 Diffuse crescentic glomerulonephritis
0.000 0.820 0.179
N00.6 Dense deposit disease
0.000 0.820 0.179
N00.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.820 0.179
N00.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.820 0.179
N00.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.820 0.179
N00.2 Diffuse membranous glomerulonephritis
0.000 0.820 0.179
N00.1 Focal and segmental glomerular lesions
0.000 0.820 0.179
N00.0 Minor glomerular abnormality
0.000 0.820 0.179
C45.9 Mesothelioma, unspecified
0.000 0.822 0.178
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.822 0.178
N43.1 Infected hydrocele
0.000 0.823 0.177
C45.7 Mesothelioma of other sites
0.000 0.823 0.176
C74.0 Cortex of adrenal gland
0.001 0.824 0.175
C41.0 Bones of skull and face
0.001 0.824 0.175
N34.0 Urethral abscess
0.000 0.824 0.176
C75 Malignant neoplasm of other endocrine glands and related structures
0.001 0.825 0.173
C17.9 Small intestine, unspecified
0.000 0.827 0.173
N01.9 Unspecified
0.000 0.828 0.172
N01.8 Other
0.000 0.828 0.172
N01.7 Diffuse crescentic glomerulonephritis
0.000 0.828 0.172
N01.6 Dense deposit disease
0.000 0.828 0.172
N01.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.828 0.172
N01.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.828 0.172
N01.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.828 0.172
N01.2 Diffuse membranous glomerulonephritis
0.000 0.828 0.172
N01.1 Focal and segmental glomerular lesions
0.000 0.828 0.172
N01.0 Minor glomerular abnormality
0.000 0.828 0.172
N06.9 Unspecified
0.000 0.828 0.172
N06.8 Other
0.000 0.828 0.172
N06.7 Diffuse crescentic glomerulonephritis
0.000 0.828 0.172
N06.6 Dense deposit disease
0.000 0.828 0.172
N06.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.828 0.172
N06.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.828 0.172
N06.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.828 0.172
N06.2 Diffuse membranous glomerulonephritis
0.000 0.828 0.172
N06.1 Focal and segmental glomerular lesions
0.000 0.828 0.172
N06.0 Minor glomerular abnormality
0.000 0.828 0.172
N07.9 Unspecified
0.000 0.828 0.172
N07.8 Other
0.000 0.828 0.172
N07.7 Diffuse crescentic glomerulonephritis
0.000 0.828 0.172
N07.6 Dense deposit disease
0.000 0.828 0.172
N07.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.828 0.172
N07.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.828 0.172
N07.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.828 0.172
N07.2 Diffuse membranous glomerulonephritis
0.000 0.828 0.172
N07.1 Focal and segmental glomerular lesions
0.000 0.828 0.172
N07.0 Minor glomerular abnormality
0.000 0.828 0.172
D06.0 Endocervix
0.000 0.829 0.171
C15 Malignant neoplasm of oesophagus
0.000 0.829 0.171
D02.0 Larynx
0.001 0.830 0.170
C74.9 Adrenal gland, unspecified
0.001 0.831 0.169
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.000 0.832 0.168
D48.7 Other specified sites
0.000 0.832 0.167
C40.2 Long bones of lower limb
0.001 0.833 0.166
C74.1 Medulla of adrenal gland
0.001 0.833 0.167
N43.4 Spermatocele
0.000 0.833 0.167
D48.1 Connective and other soft tissue
0.000 0.834 0.166
C60 Malignant neoplasm of penis
0.001 0.834 0.165
C24.0 Extrahepatic bile duct
0.000 0.834 0.166
N43.2 Other hydrocele
0.000 0.836 0.164
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.837 0.163
C47.1 Peripheral nerves of upper limb, including shoulder
0.001 0.839 0.161
Z46.6 Fitting and adjustment of urinary device
0.000 0.841 0.159
C49 Malignant neoplasm of other connective and soft tissue
0.000 0.841 0.158

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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