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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3176007
log Bayes Factor = 13.5999
Chromosome 6   position 31,236,845  (GRCh37) Explore rs3176007 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.003 0.997
# Top node
0.000 0.003 0.997
E10 Insulin-dependent diabetes mellitus
0.000 0.004 0.996
D50-D53 Nutritional anaemias
0.000 0.006 0.994
D50 Iron deficiency anaemia
0.000 0.007 0.993
D50.9 Iron deficiency anaemia, unspecified
0.000 0.008 0.992
M06 Other rheumatoid arthritis
0.000 0.010 0.990
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.013 0.987
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.014 0.986
E10.9 Without complications
0.000 0.014 0.986
D60-D64 Aplastic and other anaemias
0.000 0.024 0.976
M05-M14 Inflammatory polyarthropathies
0.000 0.028 0.972
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.031 0.969
D64 Other anaemias
0.000 0.043 0.957
L08 Other local infections of skin and subcutaneous tissue
0.000 0.043 0.957
Chapter I Certain infectious and parasitic diseases
0.000 0.047 0.953
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.054 0.946
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.054 0.946
D64.9 Anaemia, unspecified
0.000 0.056 0.944
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.073 0.927
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.085 0.915
E10.3 With ophthalmic complications
0.000 0.086 0.914
L57.0 Actinic keratosis
0.000 0.089 0.911
B35-B49 Mycoses
0.000 0.095 0.905
E70-E90 Metabolic disorders
0.000 0.101 0.899
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.103 0.897
B25-B34 Other viral diseases
0.000 0.106 0.894
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.106 0.894
E14 Unspecified diabetes mellitus
0.000 0.106 0.894
B37 Candidiasis
0.000 0.114 0.886
M06.0 Seronegative rheumatoid arthritis
0.000 0.118 0.882
M07 Psoriatic and enteropathic arthropathies
0.000 0.122 0.878
Chapter VI Diseases of the nervous system
0.000 0.137 0.863
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.138 0.862
B37.8 Candidiasis of other sites
0.000 0.142 0.858
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.144 0.856
B34 Viral infection of unspecified site
0.000 0.147 0.853
Chapter VII Diseases of the eye and adnexa
0.000 0.148 0.852
E06 Thyroiditis
0.000 0.150 0.850
N48 Other disorders of penis
0.844 0.156 0.000
N40-N51 Diseases of male genital organs
0.841 0.159 0.000
L40.0 Psoriasis vulgaris
0.000 0.162 0.838
N43 Hydrocele and spermatocele
0.837 0.163 0.000
N48.6 Balanitis xerotica obliterans
0.837 0.163 0.000
N43.3 Hydrocele, unspecified
0.836 0.164 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.165 0.835
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.176 0.824
E86 Volume depletion
0.000 0.176 0.824
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.176 0.824
B34.9 Viral infection, unspecified
0.000 0.177 0.823
E50-E64 Other nutritional deficiencies
0.000 0.180 0.820
E40-E46 Malnutrition
0.000 0.181 0.819
E14.9 Without complications
0.000 0.181 0.819
B37.0 Candidal stomatitis
0.000 0.182 0.818
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.183 0.817
M07.3 Other psoriatic arthropathies
0.000 0.190 0.810
M05 Seropositive rheumatoid arthritis
0.000 0.192 0.808
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.195 0.805
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.195 0.805
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.204 0.796
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.204 0.796
G35 Multiple sclerosis
0.000 0.207 0.793
D61 Other aplastic anaemias
0.000 0.207 0.793
G30-G32 Other degenerative diseases of the nervous system
0.000 0.209 0.791
N41 Inflammatory diseases of prostate
0.791 0.209 0.000
E10.5 With peripheral circulatory complications
0.000 0.218 0.781
H43-H45 Disorders of vitreous body and globe
0.000 0.219 0.781
N48.0 Leukoplakia of penis
0.775 0.225 0.000
H53-H54 Visual disturbances and blindness
0.000 0.226 0.774
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.235 0.765
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.238 0.762
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.240 0.760
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.244 0.756
A30-A49 Other bacterial diseases
0.000 0.246 0.754
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.257 0.743
E06.3 Autoimmune thyroiditis
0.000 0.257 0.743
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.259 0.741
N50 Other disorders of male genital organs
0.741 0.259 0.000
E10.4 With neurological complications
0.000 0.264 0.736
N48.8 Other specified disorders of penis
0.734 0.266 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.269 0.731
H43 Disorders of vitreous body
0.000 0.270 0.730
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.270 0.730
E11 Non-insulin-dependent diabetes mellitus
0.000 0.271 0.729
H53 Visual disturbances
0.000 0.274 0.726
D51 Vitamin B12 deficiency anaemia
0.000 0.274 0.726
E10.1 With ketoacidosis
0.000 0.275 0.725
M11 Other crystal arthropathies
0.000 0.277 0.723
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E03.8 Other specified hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
L10-L14 Bullous disorders
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
D55-D59 Haemolytic anaemias
0.000 0.285 0.715
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.285 0.714
A00-A09 Intestinal infectious diseases
0.000 0.286 0.714
E10.8 With unspecified complications
0.000 0.286 0.714
E10.7 With multiple complications
0.000 0.286 0.714
E10.6 With other specified complications
0.000 0.286 0.714
E10.2 With renal complications
0.000 0.286 0.714
E10.0 With coma
0.000 0.286 0.714
D53 Other nutritional anaemias
0.000 0.287 0.713
D50.1 Sideropenic dysphagia
0.000 0.288 0.712
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.289 0.711
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.289 0.711
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.290 0.710
M06.8 Other specified rheumatoid arthritis
0.000 0.290 0.709
M06.2 Rheumatoid bursitis
0.000 0.290 0.709
M06.1 Adult-onset Still's disease
0.000 0.290 0.709
N41.9 Inflammatory disease of prostate, unspecified
0.708 0.292 0.000
H40-H42 Glaucoma
0.000 0.292 0.708
L04 Acute lymphadenitis
0.000 0.293 0.707
L01 Impetigo
0.000 0.293 0.707
L00 Staphylococcal scalded skin syndrome
0.000 0.293 0.707
D52 Folate deficiency anaemia
0.000 0.293 0.707
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.294 0.706
B99-B99 Other infectious diseases
0.000 0.294 0.705
M06.4 Inflammatory polyarthropathy
0.000 0.295 0.705
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.295 0.705
B35 Dermatophytosis
0.000 0.296 0.704
N48.2 Other inflammatory disorders of penis
0.704 0.296 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.300 0.699
M00-M03 Infectious arthropathies
0.000 0.301 0.698
N50.8 Other specified disorders of male genital organs
0.697 0.303 0.000
M12 Other specific arthropathies
0.000 0.303 0.697
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.303 0.697
M08 Juvenile arthritis
0.000 0.303 0.697
L05 Pilonidal cyst
0.000 0.303 0.697
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.304 0.696
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.306 0.694
L58 Radiodermatitis
0.000 0.306 0.694
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.306 0.694
L55 Sunburn
0.000 0.306 0.694
M14 Arthropathies in other diseases classified elsewhere
0.000 0.306 0.694
E13 Other specified diabetes mellitus
0.000 0.306 0.693
M65-M68 Disorders of synovium and tendon
0.000 0.309 0.691
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.309 0.691
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.310 0.690
L20-L30 Dermatitis and eczema
0.000 0.310 0.690
E46 Unspecified protein-energy malnutrition
0.000 0.310 0.690
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.312 0.688
M06.3 Rheumatoid nodule
0.000 0.314 0.686
D64.8 Other specified anaemias
0.000 0.314 0.686
D64.4 Congenital dyserythropoietic anaemia
0.000 0.314 0.686
D64.3 Other sideroblastic anaemias
0.000 0.314 0.686
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.314 0.686
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.314 0.686
D64.0 Hereditary sideroblastic anaemia
0.000 0.314 0.686
L08.1 Erythrasma
0.000 0.314 0.686
L08.0 Pyoderma
0.000 0.314 0.686
E88 Other metabolic disorders
0.000 0.314 0.686
E53 Deficiency of other B group vitamins
0.000 0.316 0.684
D72 Other disorders of white blood cells
0.000 0.316 0.684
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.317 0.683
B50-B64 Protozoal diseases
0.000 0.317 0.683
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.317 0.683
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.317 0.683
A75-A79 Rickettsioses
0.000 0.317 0.683
A70-A74 Other diseases caused by chlamydiae
0.000 0.317 0.683
A65-A69 Other spirochaetal diseases
0.000 0.317 0.683
A20-A28 Certain zoonotic bacterial diseases
0.000 0.317 0.683
A15-A19 Tuberculosis
0.000 0.317 0.683
N42 Other disorders of prostate
0.682 0.318 0.000
M45-M49 Spondylopathies
0.000 0.320 0.680
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.321 0.678
L57.5 Actinic granuloma
0.000 0.321 0.678
L57.4 Cutis laxa senilis
0.000 0.321 0.678
L57.3 Poikiloderma of Civatte
0.000 0.321 0.678
L57.2 Cutis rhomboidalis nuchae
0.000 0.321 0.678
L57.1 Actinic reticuloid
0.000 0.321 0.678
G70-G73 Diseases of myoneural junction and muscle
0.000 0.322 0.678
B15-B19 Viral hepatitis
0.000 0.328 0.672
E04 Other non-toxic goitre
0.000 0.329 0.671
H53.2 Diplopia
0.000 0.330 0.670
D80-D89 Certain disorders involving the immune mechanism
0.000 0.330 0.670
E80.4 Gilbert's syndrome
0.000 0.331 0.669
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.335 0.665
B65-B83 Helminthiases
0.000 0.335 0.665
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.335 0.665
L81 Other disorders of pigmentation
0.000 0.337 0.663
D61.9 Aplastic anaemia, unspecified
0.000 0.338 0.662
N48.9 Disorder of penis, unspecified
0.659 0.341 0.000
E07 Other disorders of thyroid
0.000 0.343 0.657
H30-H36 Disorders of choroid and retina
0.000 0.345 0.655
N41.0 Acute prostatitis
0.654 0.346 0.000
G30 Alzheimer's disease
0.000 0.351 0.649
B48 Other mycoses, not elsewhere classified
0.000 0.351 0.648
B47 Mycetoma
0.000 0.351 0.648
B46 Zygomycosis
0.000 0.351 0.648
B45 Cryptococcosis
0.000 0.351 0.648
B43 Chromomycosis and phaeomycotic abscess
0.000 0.351 0.648
B42 Sporotrichosis
0.000 0.351 0.648
B41 Paracoccidioidomycosis
0.000 0.351 0.648
B40 Blastomycosis
0.000 0.351 0.648
B39 Histoplasmosis
0.000 0.351 0.648
B38 Coccidioidomycosis
0.000 0.351 0.648
B36 Other superficial mycoses
0.000 0.351 0.648
H43.3 Other vitreous opacities
0.000 0.353 0.647
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.355 0.645
M45 Ankylosing spondylitis
0.000 0.355 0.645
E84 Cystic fibrosis
0.000 0.355 0.645
E79 Disorders of purine and pyrimidine metabolism
0.000 0.355 0.645
E77 Disorders of glycoprotein metabolism
0.000 0.355 0.645
E76 Disorders of glycosaminoglycan metabolism
0.000 0.355 0.645
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.355 0.645
E73 Lactose intolerance
0.000 0.355 0.645
E72 Other disorders of amino-acid metabolism
0.000 0.355 0.645
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.355 0.645
E70 Disorders of aromatic amino-acid metabolism
0.000 0.355 0.645
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.355 0.645
E65-E68 Obesity and other hyperalimentation
0.000 0.357 0.643
E14.3 With ophthalmic complications
0.000 0.358 0.642
B33 Other viral diseases, not elsewhere classified
0.000 0.359 0.641
B30 Viral conjunctivitis
0.000 0.359 0.641
B27 Infectious mononucleosis
0.000 0.359 0.641
B26 Mumps
0.000 0.359 0.641
B25 Cytomegaloviral disease
0.000 0.359 0.641
E14.8 With unspecified complications
0.000 0.359 0.641
E14.7 With multiple complications
0.000 0.359 0.641
E14.6 With other specified complications
0.000 0.359 0.641
E14.5 With peripheral circulatory complications
0.000 0.359 0.641
E14.4 With neurological complications
0.000 0.359 0.641
E14.2 Withrenal complications
0.000 0.359 0.641
E14.1 With ketoacidosis
0.000 0.359 0.641
E14.0 With coma
0.000 0.359 0.641
B37.3 Candidiasis of vulva and vagina
0.000 0.363 0.637
B37.7 Candidal septicaemia
0.000 0.365 0.635
B37.6 Candidal endocarditis
0.000 0.365 0.635
B37.5 Candidal meningitis
0.000 0.365 0.635
B37.4 Candidiasis of other urogenital sites
0.000 0.365 0.635
B37.2 Candidiasis of skin and nail
0.000 0.365 0.635
B37.1 Pulmonary candidiasis
0.000 0.365 0.635
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.366 0.634
D73 Diseases of spleen
0.000 0.367 0.633
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.367 0.632
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.367 0.632
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.367 0.632
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.367 0.632
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.367 0.632
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.367 0.632
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.367 0.632
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.367 0.632
N47 Redundant prepuce, phimosis and paraphimosis
0.632 0.368 0.000
E11.3 With ophthalmic complications
0.000 0.369 0.631
L91 Hypertrophic disorders of skin
0.000 0.370 0.630
M07.6 Other enteropathic arthropathies
0.000 0.370 0.629
M07.5 Arthropathy in ulcerative colitis
0.000 0.370 0.629
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.370 0.629
M07.2 Psoriatic spondylitis
0.000 0.370 0.629
M07.1 Arthritis mutilans
0.000 0.370 0.629
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.370 0.629
L85 Other epidermal thickening
0.000 0.371 0.629
N41.1 Chronic prostatitis
0.629 0.371 0.000
H43.8 Other disorders of vitreous body
0.000 0.371 0.629
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.371 0.629
D75 Other diseases of blood and blood-forming organs
0.000 0.372 0.628
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.372 0.628
H36 Retinal disorders in diseases classified elsewhere
0.000 0.372 0.628
D62 Acute posthaemorrhagic anaemia
0.000 0.375 0.625
E05.9 Thyrotoxicosis, unspecified
0.000 0.376 0.624
Chapter XXII Codes for special purposes
0.000 0.377 0.623
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.377 0.623
E89.3 Postprocedural hypopituitarism
0.000 0.377 0.622
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.380 0.620
M60-M63 Disorders of muscles
0.000 0.381 0.619
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.382 0.618
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.382 0.618
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.382 0.618
E89.5 Postprocedural testicular hypofunction
0.000 0.382 0.618
E89.4 Postprocedural ovarian failure
0.000 0.382 0.618
E89.2 Postprocedural hypoparathyroidism
0.000 0.382 0.618
E89.1 Postprocedural hypoinsulinaemia
0.000 0.382 0.618
G37 Other demyelinating diseases of central nervous system
0.000 0.382 0.618
E74 Other disorders of carbohydrate metabolism
0.000 0.384 0.616
N42.8 Other specified disorders of prostate
0.613 0.387 0.000
A80-A89 Viral infections of the central nervous system
0.000 0.387 0.613
N45 Orchitis and epididymitis
0.613 0.387 0.000
B34.8 Other viral infections of unspecified site
0.000 0.389 0.611
B34.4 Papovirus infection, unspecified
0.000 0.389 0.611
B34.3 Parvovirus infection, unspecified
0.000 0.389 0.611
B34.2 Coronavirus infection, unspecified
0.000 0.389 0.611
B34.1 Enterovirus infection, unspecified
0.000 0.389 0.611
B34.0 Adenovirus infection, unspecified
0.000 0.389 0.611
G31.8 Other specified degenerative diseases of nervous system
0.000 0.390 0.610
E06.9 Thyroiditis, unspecified
0.000 0.390 0.609
E06.5 Other chronic thyroiditis
0.000 0.390 0.609
E06.4 Drug-induced thyroiditis
0.000 0.390 0.609
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.390 0.609
E06.1 Subacute thyroiditis
0.000 0.390 0.609
E06.0 Acute thyroiditis
0.000 0.390 0.609
N50.9 Disorder of male genital organs, unspecified
0.609 0.391 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.391 0.609
H36.0 Diabetic retinopathy
0.000 0.392 0.608
H10-H13 Disorders of conjunctiva
0.000 0.392 0.608
G62 Other polyneuropathies
0.000 0.393 0.607
M10 Gout
0.000 0.393 0.607
L89 Decubitus ulcer
0.000 0.394 0.606
N48.5 Ulcer of penis
0.605 0.395 0.000
N48.3 Priapism
0.605 0.395 0.000
H40 Glaucoma
0.000 0.395 0.605
L81.4 Other melanin hyperpigmentation
0.000 0.396 0.604
M80-M85 Disorders of bone density and structure
0.000 0.396 0.603
N51 Disorders of male genital organs in diseases classified elsewhere
0.603 0.397 0.000
N46 Male infertility
0.603 0.397 0.000
N44 Torsion of testis
0.603 0.397 0.000
N43.4 Spermatocele
0.600 0.400 0.000
N43.2 Other hydrocele
0.600 0.400 0.000
N43.1 Infected hydrocele
0.600 0.400 0.000
N43.0 Encysted hydrocele
0.600 0.400 0.000
H53.1 Subjective visual disturbances
0.000 0.401 0.599
D72.8 Other specified disorders of white blood cells
0.000 0.401 0.599
L42 Pityriasis rosea
0.000 0.402 0.598
E61 Deficiency of other nutrient elements
0.000 0.402 0.598
M91-M94 Chondropathies
0.000 0.404 0.596
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.404 0.596
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.404 0.596
A41 Other septicaemia
0.000 0.407 0.593
G36 Other acute disseminated demyelination
0.000 0.409 0.591
E55 Vitamin D deficiency
0.000 0.411 0.589
A46 Erysipelas
0.000 0.412 0.588
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.412 0.588
E63 Other nutritional deficiencies
0.000 0.412 0.588
E56 Other vitamin deficiencies
0.000 0.412 0.588
E51 Thiamine deficiency
0.000 0.412 0.588
E50 Vitamin A deficiency
0.000 0.412 0.588
E60 Dietary zinc deficiency
0.000 0.412 0.588
E59 Dietary selenium deficiency
0.000 0.412 0.588
E58 Dietary calcium deficiency
0.000 0.412 0.588
E54 Ascorbic acid deficiency
0.000 0.412 0.588
E52 Niacin deficiency [pellagra]
0.000 0.412 0.588
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.412 0.587
E45 Retarded development following protein-energy malnutrition
0.000 0.412 0.587
E43 Unspecified severe protein-energy malnutrition
0.000 0.412 0.587
E42 Marasmic kwashiorkor
0.000 0.412 0.587
E41 Nutritional marasmus
0.000 0.412 0.587
E40 Kwashiorkor
0.000 0.412 0.587
E53.8 Deficiency of other specified B group vitamins
0.000 0.413 0.587
M65 Synovitis and tenosynovitis
0.000 0.413 0.587
G70 Myasthenia gravis and other myoneural disorders
0.000 0.414 0.586
L43 Lichen planus
0.000 0.414 0.586
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.416 0.584
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.416 0.584
L83 Acanthosis nigricans
0.000 0.418 0.582
M07.38 Other psoriatic arthropathies (Other)
0.000 0.419 0.581
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.419 0.581
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.419 0.581
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.419 0.581
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.419 0.581
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.419 0.581
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.419 0.581
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.419 0.581
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.419 0.581
H02 Other disorders of eyelid
0.000 0.421 0.579
M05.8 Other seropositive rheumatoid arthritis
0.000 0.421 0.579
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.421 0.579
M05.2 Rheumatoid vasculitis
0.000 0.421 0.579
M05.1 Rheumatoid lung disease
0.000 0.421 0.579
M05.0 Felty's syndrome
0.000 0.421 0.579
E05.5 Thyroid crisis or storm
0.000 0.422 0.577
E05.4 Thyrotoxicosis factitia
0.000 0.422 0.577
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.422 0.577
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.422 0.577
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.422 0.577
D74 Methaemoglobinaemia
0.000 0.422 0.577
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.422 0.577
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.422 0.577
M95.0 Acquired deformity of nose
0.000 0.424 0.576
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.425 0.575
L03 Cellulitis
0.000 0.426 0.574
A08 Viral and other specified intestinal infections
0.000 0.426 0.574
L05.0 Pilonidal cyst with abscess
0.000 0.428 0.572
L50-L54 Urticaria and erythema
0.000 0.429 0.570
D61.8 Other specified aplastic anaemias
0.000 0.431 0.569
D61.3 Idiopathic aplastic anaemia
0.000 0.431 0.569
D61.2 Aplastic anaemia due to other external agents
0.000 0.431 0.569
D61.1 Drug-induced aplastic anaemia
0.000 0.431 0.569
D61.0 Constitutional aplastic anaemia
0.000 0.431 0.569
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.432 0.567
N41.8 Other inflammatory diseases of prostate
0.567 0.433 0.000
N41.3 Prostatocystitis
0.567 0.433 0.000
N41.2 Abscess of prostate
0.567 0.433 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.434 0.566
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.562 0.437 0.000
H53.9 Visual disturbance, unspecified
0.000 0.438 0.562
G80 Infantile cerebral palsy
0.000 0.438 0.562
E11.1 With ketoacidosis
0.000 0.438 0.562
B35.3 Tinea pedis
0.000 0.439 0.561
B49 Unspecified mycosis
0.000 0.440 0.560
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.440 0.560
H44 Disorders of globe
0.000 0.441 0.559
L29 Pruritus
0.000 0.441 0.559
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.442 0.558
G81 Hemiplegia
0.000 0.442 0.558
D50.8 Other iron deficiency anaemias
0.000 0.443 0.557
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.443 0.557
N48.4 Impotence of organic origin
0.556 0.444 0.000
H02.0 Entropion and trichiasis of eyelid
0.000 0.445 0.555
H43.1 Vitreous haemorrhage
0.000 0.451 0.549
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.451 0.549
E80.6 Other disorders of bilirubin metabolism
0.000 0.451 0.549
E80.5 Crigler-Najjar syndrome
0.000 0.451 0.549
E80.3 Defects of catalase and peroxydase
0.000 0.451 0.549
E80.2 Other porphyria
0.000 0.451 0.549
E80.1 Porphyria cutanea tarda
0.000 0.451 0.549
E80.0 Hereditary erythropoietic porphyria
0.000 0.451 0.549
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.452 0.548
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.453 0.547
G30.9 Alzheimer's disease, unspecified
0.000 0.453 0.547
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.455 0.545
L94 Other localised connective tissue disorders
0.000 0.455 0.545
L87 Transepidermal elimination disorders
0.000 0.455 0.545
L88 Pyoderma gangrenosum
0.000 0.455 0.545
L86 Keratoderma in diseases classified elsewhere
0.000 0.455 0.545
L80 Vitiligo
0.000 0.455 0.545
M11.2 Other chondrocalcinosis
0.000 0.456 0.544
G62.9 Polyneuropathy, unspecified
0.000 0.457 0.543
E85 Amyloidosis
0.000 0.458 0.542
M86-M90 Other osteopathies
0.000 0.459 0.541
A48 Other bacterial diseases, not elsewhere classified
0.000 0.459 0.541
A44 Bartonellosis
0.000 0.459 0.541
A43 Nocardiosis
0.000 0.459 0.541
A42 Actinomycosis
0.000 0.459 0.541
A39 Meningococcal infection
0.000 0.459 0.541
A37 Whooping cough
0.000 0.459 0.541
A36 Diphtheria
0.000 0.459 0.541
A32 Listeriosis
0.000 0.459 0.541
A31 Infection due to other mycobacteria
0.000 0.459 0.541
A30 Leprosy [Hansen's disease]
0.000 0.459 0.541
A38 Scarlet fever
0.000 0.459 0.541
A35 Other tetanus
0.000 0.459 0.541
A34 Obstetrical tetanus
0.000 0.459 0.541
A33 Tetanus neonatorum
0.000 0.459 0.541
M65.3 Trigger finger
0.000 0.460 0.540
L91.8 Other hypertrophic disorders of skin
0.000 0.461 0.539
H40.9 Glaucoma, unspecified
0.000 0.461 0.539
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.000 0.461 0.538
M80 Osteoporosis with pathological fracture
0.000 0.463 0.537
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.464 0.536
G90-G99 Other disorders of the nervous system
0.000 0.465 0.535
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.465 0.535
H40.0 Glaucoma suspect
0.000 0.465 0.535
A49 Bacterial infection of unspecified site
0.000 0.465 0.535
L93 Lupus erythematosus
0.000 0.466 0.534
M99 Biomechanical lesions, not elsewhere classified
0.000 0.467 0.533
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.468 0.532
H53.8 Other visual disturbances
0.000 0.468 0.532
H55-H59 Other disorders of eye and adnexa
0.000 0.469 0.531
B99 Other and unspecified infectious diseases
0.000 0.472 0.528
H53.4 Visual field defects
0.000 0.473 0.527
E11.2 With renal complications
0.000 0.475 0.525
E11.0 With coma
0.000 0.475 0.525
H43.9 Disorder of vitreous body, unspecified
0.000 0.476 0.524
H43.2 Crystalline deposits in vitreous body
0.000 0.476 0.524
H43.0 Vitreous prolapse
0.000 0.476 0.524
L28 Lichen simplex chronicus and prurigo
0.000 0.476 0.523
E11.8 With unspecified complications
0.000 0.477 0.523
E11.7 With multiple complications
0.000 0.477 0.523
M00 Pyogenic arthritis
0.000 0.479 0.521
D73.0 Hyposplenism
0.000 0.479 0.521
H53.6 Night blindness
0.000 0.479 0.521
H53.5 Colour vision deficiencies
0.000 0.479 0.521
H53.3 Other disorders of binocular vision
0.000 0.479 0.521
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.479 0.520
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.479 0.520
D51.2 Transcobalamin II deficiency
0.000 0.479 0.520
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.479 0.520
H54 Blindness and low vision
0.000 0.479 0.520
G70.0 Myasthenia gravis
0.000 0.480 0.520
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.480 0.519
M46 Other inflammatory spondylopathies
0.000 0.481 0.519

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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