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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3198005
log Bayes Factor = 12.1016
Chromosome 6   position 32,813,214  (GRCh37) Explore rs3198005 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.005 0.995
E11 Non-insulin-dependent diabetes mellitus
0.000 0.013 0.987
E11.9 Without complications
0.000 0.027 0.973
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.045 0.955
E00-E07 Disorders of thyroid gland
0.000 0.058 0.942
E03 Other hypothyroidism
0.000 0.062 0.938
E03.9 Hypothyroidism, unspecified
0.000 0.066 0.934
E10.1 With ketoacidosis
0.000 0.069 0.931
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.128 0.872
E70-E90 Metabolic disorders
0.000 0.134 0.866
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.149 0.851
E78.0 Pure hypercholesterolaemia
0.000 0.160 0.840
E16 Other disorders of pancreatic internal secretion
0.000 0.187 0.813
E11.2 With renal complications
0.000 0.195 0.805
E11.3 With ophthalmic complications
0.000 0.200 0.800
G35-G37 Demyelinating diseases of the central nervous system
0.796 0.204 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.229 0.771
E11.1 With ketoacidosis
0.000 0.242 0.758
E11.4 With neurological complications
0.000 0.252 0.748
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.255 0.745
E07 Other disorders of thyroid
0.000 0.267 0.733
E13 Other specified diabetes mellitus
0.000 0.282 0.718
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.5 With peripheral circulatory complications
0.000 0.283 0.717
E10.4 With neurological complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E40-E46 Malnutrition
0.000 0.287 0.713
E11.7 With multiple complications
0.000 0.292 0.708
E11.6 With other specified complications
0.000 0.292 0.708
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.295 0.705
E06 Thyroiditis
0.000 0.295 0.705
E11.0 With coma
0.000 0.302 0.698
E03.8 Other specified hypothyroidism
0.000 0.303 0.697
E88 Other metabolic disorders
0.000 0.304 0.696
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.324 0.676
E00 Congenital iodine-deficiency syndrome
0.000 0.324 0.676
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.324 0.676
E03.5 Myxoedema coma
0.000 0.328 0.672
E03.4 Atrophy of thyroid (acquired)
0.000 0.328 0.672
E03.3 Postinfectious hypothyroidism
0.000 0.328 0.672
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.328 0.672
E03.1 Congenital hypothyroidism without goitre
0.000 0.328 0.672
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.328 0.672
G37 Other demyelinating diseases of central nervous system
0.668 0.332 0.000
E11.5 With peripheral circulatory complications
0.000 0.335 0.665
E78.2 Mixed hyperlipidaemia
0.000 0.353 0.647
E78.8 Other disorders of lipoprotein metabolism
0.000 0.362 0.638
E89.0 Postprocedural hypothyroidism
0.000 0.367 0.633
E15 Nondiabetic hypoglycaemic coma
0.000 0.375 0.625
E84 Cystic fibrosis
0.000 0.379 0.621
E79 Disorders of purine and pyrimidine metabolism
0.000 0.379 0.621
E77 Disorders of glycoprotein metabolism
0.000 0.379 0.621
E76 Disorders of glycosaminoglycan metabolism
0.000 0.379 0.621
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.379 0.621
E72 Other disorders of amino-acid metabolism
0.000 0.379 0.621
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.379 0.621
E70 Disorders of aromatic amino-acid metabolism
0.000 0.379 0.621
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.379 0.621
E85 Amyloidosis
0.000 0.383 0.616
E78.6 Lipoprotein deficiency
0.000 0.390 0.610
E78.4 Other hyperlipidaemia
0.000 0.390 0.610
E78.3 Hyperchylomicronaemia
0.000 0.390 0.610
E07.9 Disorder of thyroid, unspecified
0.000 0.393 0.607
E73 Lactose intolerance
0.000 0.401 0.599
E11.8 With unspecified complications
0.000 0.402 0.597
E78.1 Pure hyperglyceridaemia
0.000 0.403 0.597
E89.2 Postprocedural hypoparathyroidism
0.000 0.415 0.585
G37.9 Demyelinating disease of central nervous system, unspecified
0.584 0.416 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.416 0.583
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.417 0.583
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.417 0.583
E16.4 Abnormal secretion of gastrin
0.000 0.417 0.583
E16.3 Increased secretion of glucagon
0.000 0.417 0.583
E16.1 Other hypoglycaemia
0.000 0.417 0.583
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.417 0.583
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.419 0.581
E78.5 Hyperlipidaemia, unspecified
0.000 0.421 0.579
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.424 0.576
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.426 0.574
G36 Other acute disseminated demyelination
0.571 0.429 0.000
E14 Unspecified diabetes mellitus
0.000 0.430 0.570
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.444 0.556
E86 Volume depletion
0.000 0.448 0.552
E83 Disorders of mineral metabolism
0.000 0.450 0.550
K90.0 Coeliac disease
0.000 0.456 0.544
Chapter VI Diseases of the nervous system
0.540 0.460 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.461 0.539
E65-E68 Obesity and other hyperalimentation
0.000 0.463 0.537
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.465 0.534
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.465 0.534
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.465 0.534
E89.5 Postprocedural testicular hypofunction
0.000 0.465 0.534
E89.4 Postprocedural ovarian failure
0.000 0.465 0.534
E89.1 Postprocedural hypoinsulinaemia
0.000 0.465 0.534
E06.3 Autoimmune thyroiditis
0.000 0.466 0.534
E89.3 Postprocedural hypopituitarism
0.000 0.468 0.532
E07.1 Dyshormogenetic goitre
0.000 0.475 0.525
E07.0 Hypersecretion of calcitonin
0.000 0.475 0.525
E13.9 Without complications
0.000 0.481 0.518
E13.8 With unspecified complications
0.000 0.485 0.515
E13.7 With multiple complications
0.000 0.485 0.515
E13.6 With other specified complications
0.000 0.485 0.515
E13.5 With peripheral circulatory complications
0.000 0.485 0.515
E13.4 With neurological complications
0.000 0.485 0.515
E13.3 With ophthalmic complications
0.000 0.485 0.515
E13.2 With renal complications
0.000 0.485 0.515
E13.1 With ketoacidosis
0.000 0.485 0.515
E13.0 With coma
0.000 0.485 0.515
G80-G83 Cerebral palsy and other paralytic syndromes
0.515 0.485 0.000
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.489 0.511
E45 Retarded development following protein-energy malnutrition
0.000 0.489 0.511
E43 Unspecified severe protein-energy malnutrition
0.000 0.489 0.511
E42 Marasmic kwashiorkor
0.000 0.489 0.511
E41 Nutritional marasmus
0.000 0.489 0.511
E40 Kwashiorkor
0.000 0.489 0.511
E05.8 Other thyrotoxicosis
0.000 0.494 0.506
E05.5 Thyroid crisis or storm
0.000 0.494 0.506
E05.4 Thyrotoxicosis factitia
0.000 0.494 0.506
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.494 0.506
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.494 0.506
E06.9 Thyroiditis, unspecified
0.000 0.495 0.505
E06.5 Other chronic thyroiditis
0.000 0.495 0.505
E06.4 Drug-induced thyroiditis
0.000 0.495 0.505
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.495 0.505
E06.1 Subacute thyroiditis
0.000 0.495 0.505
E06.0 Acute thyroiditis
0.000 0.495 0.505
E88.9 Metabolic disorder, unspecified
0.000 0.501 0.499
E88.8 Other specified metabolic disorders
0.000 0.501 0.499
E88.3 Tumour lysis syndrome
0.000 0.501 0.499
E88.2 Lipomatosis, not elsewhere classified
0.000 0.501 0.499
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.501 0.499
G70-G73 Diseases of myoneural junction and muscle
0.495 0.505 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.515 0.484
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.515 0.484
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.515 0.484
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.515 0.484
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.515 0.484
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.515 0.484
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.515 0.484
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.515 0.484
G82 Paraplegia and tetraplegia
0.485 0.515 0.000
E07.8 Other specified disorders of thyroid
0.000 0.516 0.484
G37.8 Other specified demyelinating diseases of central nervous system
0.479 0.521 0.000
G37.5 Concentric sclerosis [Balo]
0.479 0.521 0.000
G37.4 Subacute necrotising myelitis
0.479 0.521 0.000
G37.2 Central pontine myelinolysis
0.479 0.521 0.000
G37.1 Central demyelination of corpus callosum
0.479 0.521 0.000
G37.0 Diffuse sclerosis
0.479 0.521 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.523 0.476
G83 Other paralytic syndromes
0.462 0.538 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.461 0.539 0.000
E83.5 Disorders of calcium metabolism
0.000 0.545 0.455
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.554 0.445
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.554 0.445
E70.3 Albinism
0.000 0.554 0.445
E70.2 Disorders of tyrosine metabolism
0.000 0.554 0.445
E70.1 Other hyperphenylalaninaemias
0.000 0.554 0.445
E70.0 Classical phenylketonuria
0.000 0.554 0.445
E71.3 Disorders of fatty-acid metabolism
0.000 0.554 0.445
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.554 0.445
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.554 0.445
E71.0 Maple-syrup-urine disease
0.000 0.554 0.445
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.554 0.445
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.554 0.445
E72.5 Disorders of glycine metabolism
0.000 0.554 0.445
E72.4 Disorders of ornithine metabolism
0.000 0.554 0.445
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.554 0.445
E72.2 Disorders of urea cycle metabolism
0.000 0.554 0.445
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.554 0.445
E72.0 Disorders of amino-acid transport
0.000 0.554 0.445
E75.6 Lipid storage disorder, unspecified
0.000 0.554 0.445
E75.5 Other lipid storage disorders
0.000 0.554 0.445
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.554 0.445
E75.3 Sphingolipidosis, unspecified
0.000 0.554 0.445
E75.2 Other sphingolipidosis
0.000 0.554 0.445
E75.1 Other gangliosidosis
0.000 0.554 0.445
E75.0 GM2 gangliosidosis
0.000 0.554 0.445
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.554 0.445
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.554 0.445
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.554 0.445
E76.2 Other mucopolysaccharidoses
0.000 0.554 0.445
E76.1 Mucopolysaccharidosis, type II
0.000 0.554 0.445
E76.0 Mucopolysaccharidosis, type I
0.000 0.554 0.445
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.554 0.445
E77.8 Other disorders of glycoprotein metabolism
0.000 0.554 0.445
E77.1 Defects in glycoprotein degradation
0.000 0.554 0.445
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.554 0.445
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.554 0.445
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.554 0.445
E79.1 Lesch-Nyhan syndrome
0.000 0.554 0.445
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.554 0.445
E84.9 Cystic fibrosis, unspecified
0.000 0.554 0.445
E84.8 Cystic fibrosis with other manifestations
0.000 0.554 0.445
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.554 0.445
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.554 0.445
G71 Primary disorders of muscles
0.443 0.557 0.000
E85.9 Amyloidosis, unspecified
0.000 0.558 0.442
E85.8 Other amyloidosis
0.000 0.558 0.442
E85.3 Secondary systemic amyloidosis
0.000 0.558 0.442
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.558 0.442
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.558 0.442
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.558 0.442
E85.4 Organ-limited amyloidosis
0.000 0.563 0.437
E73.8 Other lactose intolerance
0.000 0.570 0.429
E73.1 Secondary lactase deficiency
0.000 0.570 0.429
E73.0 Congenital lactase deficiency
0.000 0.570 0.429
G82.2 Paraplegia, unspecified
0.423 0.577 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.581 0.418
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.581 0.418
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.581 0.418
E74.2 Disorders of galactose metabolism
0.000 0.581 0.418
E74.1 Disorders of fructose metabolism
0.000 0.581 0.418
E74.0 Glycogen storage disease
0.000 0.581 0.418
G00-G09 Inflammatory diseases of the central nervous system
0.417 0.583 0.000
G82.1 Spastic paraplegia
0.414 0.585 0.000
E14.3 With ophthalmic complications
0.000 0.588 0.412
G36.9 Acute disseminated demyelination, unspecified
0.409 0.590 0.000
G36.8 Other specified acute disseminated demyelination
0.409 0.590 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.409 0.590 0.000
G36.0 Neuromyelitis optica [Devic]
0.409 0.590 0.000
E14.8 With unspecified complications
0.000 0.591 0.409
E14.7 With multiple complications
0.000 0.591 0.409
E14.6 With other specified complications
0.000 0.591 0.409
E14.5 With peripheral circulatory complications
0.000 0.591 0.409
E14.4 With neurological complications
0.000 0.591 0.409
E14.2 Withrenal complications
0.000 0.591 0.409
E14.1 With ketoacidosis
0.000 0.591 0.409
E14.0 With coma
0.000 0.591 0.409
E73.9 Lactose intolerance, unspecified
0.000 0.593 0.407
G40-G47 Episodic and paroxysmal disorders
0.397 0.603 0.000
E65 Localised adiposity
0.000 0.605 0.395
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.605 0.395
E83.8 Other disorders of mineral metabolism
0.000 0.605 0.395
E83.2 Disorders of zinc metabolism
0.000 0.605 0.395
E83.0 Disorders of copper metabolism
0.000 0.605 0.395
E83.4 Disorders of magnesium metabolism
0.000 0.605 0.395
G90-G99 Other disorders of the nervous system
0.394 0.606 0.000
G82.5 Tetraplegia, unspecified
0.390 0.610 0.000
G83.4 Cauda equina syndrome
0.390 0.610 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.614 0.386
E50-E64 Other nutritional deficiencies
0.001 0.614 0.384
G70 Myasthenia gravis and other myoneural disorders
0.385 0.615 0.000
E67 Other hyperalimentation
0.000 0.615 0.385
E68 Sequelae of hyperalimentation
0.000 0.615 0.385
G72 Other myopathies
0.383 0.617 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.619 0.381
G30-G32 Other degenerative diseases of the nervous system
0.375 0.625 0.000
G83.1 Monoplegia of lower limb
0.373 0.627 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.633 0.366
E44.0 Moderate protein-energy malnutrition
0.000 0.633 0.366
G83.9 Paralytic syndrome, unspecified
0.362 0.638 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.361 0.638 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.361 0.639 0.000
G71.0 Muscular dystrophy
0.359 0.641 0.000
G71.1 Myotonic disorders
0.357 0.643 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.355 0.645 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.646 0.354
G95 Other diseases of spinal cord
0.351 0.649 0.000
G82.4 Spastic tetraplegia
0.348 0.652 0.000
G82.3 Flaccid tetraplegia
0.348 0.652 0.000
G82.0 Flaccid paraplegia
0.348 0.652 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.345 0.654 0.000
G80 Infantile cerebral palsy
0.344 0.656 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.658 0.342
E80.6 Other disorders of bilirubin metabolism
0.000 0.658 0.342
E80.5 Crigler-Najjar syndrome
0.000 0.658 0.342
E80.3 Defects of catalase and peroxydase
0.000 0.658 0.342
E80.2 Other porphyria
0.000 0.658 0.342
E80.1 Porphyria cutanea tarda
0.000 0.658 0.342
E80.0 Hereditary erythropoietic porphyria
0.000 0.658 0.342
E20-E35 Disorders of other endocrine glands
0.000 0.664 0.336
G83.8 Other specified paralytic syndromes
0.331 0.668 0.000
G83.5 Locked-in syndrome
0.331 0.668 0.000
G83.3 Monoplegia, unspecified
0.331 0.668 0.000
G83.2 Monoplegia of upper limb
0.331 0.668 0.000
G83.0 Diplegia of upper limbs
0.331 0.668 0.000
G20-G26 Extrapyramidal and movement disorders
0.331 0.669 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.322 0.678 0.000
G71.9 Primary disorder of muscle, unspecified
0.318 0.682 0.000
G71.8 Other primary disorders of muscles
0.318 0.682 0.000
G71.2 Congenital myopathies
0.318 0.682 0.000
G41 Status epilepticus
0.310 0.690 0.000
G95.9 Disease of spinal cord, unspecified
0.309 0.691 0.000
G70.0 Myasthenia gravis
0.307 0.693 0.000
G72.9 Myopathy, unspecified
0.303 0.697 0.000
G81 Hemiplegia
0.303 0.697 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.299 0.701 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.299 0.701 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.299 0.701 0.000
G00 Bacterial meningitis, not elsewhere classified
0.299 0.701 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.299 0.701 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.299 0.701 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.299 0.701 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.299 0.701 0.000
G44 Other headache syndromes
0.293 0.707 0.000
G30 Alzheimer's disease
0.293 0.707 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.288 0.712 0.000
G95.1 Vascular myelopathies
0.286 0.714 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.284 0.716 0.000
G95.8 Other specified diseases of spinal cord
0.283 0.717 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.283 0.717 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.283 0.717 0.000
G92 Toxic encephalopathy
0.283 0.717 0.000
G40 Epilepsy
0.282 0.718 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.279 0.721 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.723 0.276
E63 Other nutritional deficiencies
0.001 0.723 0.276
E56 Other vitamin deficiencies
0.001 0.723 0.276
E51 Thiamine deficiency
0.001 0.723 0.276
E50 Vitamin A deficiency
0.001 0.723 0.276
E60 Dietary zinc deficiency
0.001 0.723 0.276
E59 Dietary selenium deficiency
0.001 0.723 0.276
E58 Dietary calcium deficiency
0.001 0.723 0.276
E54 Ascorbic acid deficiency
0.001 0.723 0.276
E52 Niacin deficiency [pellagra]
0.001 0.723 0.276
G70.9 Myoneural disorder, unspecified
0.276 0.724 0.000
G70.8 Other specified myoneural disorders
0.276 0.724 0.000
G70.2 Congenital and developmental myasthenia
0.276 0.724 0.000
G70.1 Toxic myoneural disorders
0.276 0.724 0.000
E67.8 Other specified hyperalimentation
0.000 0.724 0.276
E67.3 Hypervitaminosis D
0.000 0.724 0.276
E67.2 Megavitamin-B6 syndrome
0.000 0.724 0.276
E67.1 Hypercarotenaemia
0.000 0.724 0.276
E67.0 Hypervitaminosis A
0.000 0.724 0.276
G99 Other disorders of nervous system in diseases classified elsewhere
0.276 0.724 0.000
G96 Other disorders of central nervous system
0.276 0.724 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.275 0.724 0.000
G72.8 Other specified myopathies
0.275 0.725 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.275 0.725 0.000
G72.3 Periodic paralysis
0.275 0.725 0.000
G72.2 Myopathy due to other toxic agents
0.275 0.725 0.000
G72.1 Alcoholic myopathy
0.275 0.725 0.000
G72.0 Drug-induced myopathy
0.275 0.725 0.000
G90 Disorders of autonomic nervous system
0.274 0.726 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.274 0.726 0.000
G03 Meningitis due to other and unspecified causes
0.273 0.727 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.269 0.731 0.000
G46.4 Cerebellar stroke syndrome
0.268 0.732 0.000
G40.9 Epilepsy, unspecified
0.261 0.739 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.259 0.741 0.000
G11 Hereditary ataxia
0.259 0.741 0.000
G14 Postpolio syndrome
0.259 0.741 0.000
G10 Huntington's disease
0.259 0.741 0.000
E14.9 Without complications
0.000 0.741 0.258
G47 Sleep disorders
0.257 0.743 0.000
G73.7 Myopathy other diseases classified elsewhere
0.255 0.745 0.000
G73.6 Myopathy in metabolic diseases
0.255 0.745 0.000
G73.5 Myopathy in endocrine diseases
0.255 0.745 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.255 0.745 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.255 0.745 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.255 0.745 0.000
G73.1 Eaton-Lambert syndrome
0.255 0.745 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.255 0.745 0.000
G91 Hydrocephalus
0.253 0.747 0.000
G95.0 Syringomyelia and syringobulbia
0.252 0.748 0.000
E28 Ovarian dysfunction
0.000 0.749 0.251
G41.9 Status epilepticus, unspecified
0.248 0.752 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.248 0.752 0.000
G04.1 Tropical spastic paraplegia
0.248 0.752 0.000
G04.0 Acute disseminated encephalitis
0.248 0.752 0.000
G80.8 Other infantile cerebral palsy
0.246 0.753 0.000
G80.4 Ataxic cerebral palsy
0.246 0.753 0.000
G80.3 Dyskinetic cerebral palsy
0.246 0.753 0.000
G80.2 Infantile hemiplegia
0.246 0.753 0.000
G80.1 Spastic diplegia
0.246 0.753 0.000
G80.0 Spastic cerebral palsy
0.246 0.753 0.000
K90 Intestinal malabsorption
0.000 0.755 0.245
E61 Deficiency of other nutrient elements
0.001 0.757 0.242
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.759 0.241
E34 Other endocrine disorders
0.000 0.759 0.241
E32 Diseases of thymus
0.000 0.759 0.241
E31 Polyglandular dysfunction
0.000 0.759 0.241
E30 Disorders of puberty, not elsewhere classified
0.000 0.759 0.241
E26 Hyperaldosteronism
0.000 0.759 0.241
E25 Adrenogenital disorders
0.000 0.759 0.241
E24 Cushing's syndrome
0.000 0.759 0.241
E20 Hypoparathyroidism
0.000 0.759 0.241
G43 Migraine
0.241 0.759 0.000
G24 Dystonia
0.241 0.759 0.000
E29 Testicular dysfunction
0.000 0.759 0.240
G45.3 Amaurosis fugax
0.241 0.759 0.000
G23 Other degenerative diseases of basal ganglia
0.238 0.762 0.000
G21 Secondary Parkinsonism
0.238 0.762 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.238 0.762 0.000
G22 Parkinsonism in diseases classified elsewhere
0.238 0.762 0.000
G47.9 Sleep disorder, unspecified
0.238 0.762 0.000
G30.9 Alzheimer's disease, unspecified
0.234 0.766 0.000
G12 Spinal muscular atrophy and related syndromes
0.233 0.767 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.233 0.767 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.231 0.769 0.000
G46.7 Other lacunar syndromes
0.231 0.769 0.000
G46.6 Pure sensory lacunar syndrome
0.231 0.769 0.000
G46.5 Pure motor lacunar syndrome
0.231 0.769 0.000
G46.3 Brain stem stroke syndrome
0.231 0.769 0.000
G46.2 Posterior cerebral artery syndrome
0.231 0.769 0.000
G46.1 Anterior cerebral artery syndrome
0.231 0.769 0.000
G46.0 Middle cerebral artery syndrome
0.231 0.769 0.000
G44.8 Other specified headache syndromes
0.230 0.770 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.223 0.777 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.777 0.223
G41.8 Other status epilepticus
0.223 0.777 0.000
G41.2 Complex partial status epilepticus
0.223 0.777 0.000
G41.1 Petit mal status epilepticus
0.223 0.777 0.000
G41.0 Grand mal status epilepticus
0.223 0.777 0.000
G61 Inflammatory polyneuropathy
0.222 0.777 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.221 0.778 0.000
G80.9 Infantile cerebral palsy, unspecified
0.221 0.779 0.000
G20 Parkinson's disease
0.220 0.780 0.000
G81.1 Spastic hemiplegia
0.217 0.783 0.000
G81.0 Flaccid hemiplegia
0.217 0.783 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.217 0.783 0.000
E04 Other non-toxic goitre
0.001 0.784 0.215
E66 Obesity
0.000 0.785 0.215
G00.9 Bacterial meningitis, unspecified
0.215 0.785 0.000
G00.8 Other bacterial meningitis
0.215 0.785 0.000
G00.3 Staphylococcal meningitis
0.215 0.785 0.000
G00.2 Streptococcal meningitis
0.215 0.785 0.000
G00.1 Pneumococcal meningitis
0.215 0.785 0.000
G00.0 Haemophilus meningitis
0.215 0.785 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.215 0.785 0.000
G02.1 Meningitis in mycoses
0.215 0.785 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.215 0.785 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.215 0.785 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.215 0.785 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.215 0.785 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.215 0.785 0.000
G06.2 Extradural and subdural abscess, unspecified
0.215 0.785 0.000
G06.1 Intraspinal abscess and granuloma
0.215 0.785 0.000
G06.0 Intracranial abscess and granuloma
0.215 0.785 0.000
G93 Other disorders of brain
0.213 0.787 0.000
G44.0 Cluster headache syndrome
0.213 0.787 0.000
G44.3 Chronic posttraumatic headache
0.210 0.789 0.000
G44.1 Vascular headache, not elsewhere classified
0.210 0.789 0.000
G30.8 Other Alzheimer's disease
0.210 0.790 0.000
G30.1 Alzheimer's disease with late onset
0.210 0.790 0.000
G30.0 Alzheimer's disease with early onset
0.210 0.790 0.000
E53 Deficiency of other B group vitamins
0.001 0.793 0.206
G64 Other disorders of peripheral nervous system
0.207 0.793 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.206 0.794 0.000
G47.4 Narcolepsy and cataplexy
0.205 0.795 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.204 0.796 0.000
G97.8 Other postprocedural disorders of nervous system
0.204 0.796 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.204 0.796 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.204 0.796 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.203 0.797 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.203 0.797 0.000
G94.1 Hydrocephalus in neoplastic disease
0.203 0.797 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.203 0.797 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.797 0.203
E22 Hyperfunction of pituitary gland
0.000 0.798 0.202
E83.1 Disorders of iron metabolism
0.000 0.798 0.202
G40.8 Other epilepsy
0.202 0.798 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.202 0.798 0.000
G40.5 Special epileptic syndromes
0.202 0.798 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.202 0.798 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.202 0.798 0.000
G60 Hereditary and idiopathic neuropathy
0.201 0.799 0.000
G25 Other extrapyramidal and movement disorders
0.201 0.799 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.200 0.799 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.200 0.799 0.000
G45.0 Vertebro-basilar artery syndrome
0.200 0.799 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.200 0.800 0.000
E50.9 Vitamin A deficiency, unspecified
0.001 0.801 0.198
E50.8 Other manifestations of vitamin A deficiency
0.001 0.801 0.198
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.801 0.198
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.801 0.198
E50.5 Vitamin A deficiency with night blindness
0.001 0.801 0.198
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.801 0.198
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.801 0.198
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.801 0.198
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.801 0.198
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.801 0.198
E51.9 Thiamine deficiency, unspecified
0.001 0.801 0.198
E51.8 Other manifestations of thiamine deficiency
0.001 0.801 0.198
E51.2 Wernicke's encephalopathy
0.001 0.801 0.198
E51.1 Beriberi
0.001 0.801 0.198
E56.9 Vitamin deficiency, unspecified
0.001 0.801 0.198
E56.8 Deficiency of other vitamins
0.001 0.801 0.198
E56.1 Deficiency of vitamin K
0.001 0.801 0.198
E56.0 Deficiency of vitamin E
0.001 0.801 0.198
E63.9 Nutritional deficiency, unspecified
0.001 0.801 0.198
E63.8 Other specified nutritional deficiencies
0.001 0.801 0.198

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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