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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3213485
log Bayes Factor = 169.673
Chromosome 6   position 32,724,719  (GRCh37) Explore rs3213485 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
D80-D89 Certain disorders involving the immune mechanism
1.000 0.000 0.000
D86 Sarcoidosis
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
D86.9 Sarcoidosis, unspecified
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.001 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
D50.9 Iron deficiency anaemia, unspecified
0.998 0.002 0.000
D50 Iron deficiency anaemia
0.998 0.002 0.000
E05.9 Thyrotoxicosis, unspecified
0.996 0.004 0.000
E14.9 Without complications
0.994 0.006 0.000
L40 Psoriasis
0.000 0.006 0.994
E10.4 With neurological complications
0.990 0.010 0.000
E10.2 With renal complications
0.988 0.012 0.000
L40.5 Arthropathic psoriasis
0.000 0.012 0.988
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.988 0.012 0.000
G37 Other demyelinating diseases of central nervous system
0.987 0.013 0.000
E50-E64 Other nutritional deficiencies
0.986 0.014 0.000
L60-L75 Disorders of skin appendages
0.985 0.015 0.000
H33 Retinal detachments and breaks
0.985 0.015 0.000
E14.3 With ophthalmic complications
0.978 0.022 0.000
H33.3 Retinal breaks without detachment
0.973 0.027 0.000
L20-L30 Dermatitis and eczema
0.971 0.029 0.000
E10.5 With peripheral circulatory complications
0.966 0.034 0.000
Chapter VI Diseases of the nervous system
0.966 0.034 0.000
L71 Rosacea
0.962 0.038 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.955 0.045 0.000
L10-L14 Bullous disorders
0.954 0.046 0.000
E55 Vitamin D deficiency
0.951 0.049 0.000
D51 Vitamin B12 deficiency anaemia
0.950 0.050 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.942 0.058 0.000
L71.9 Rosacea, unspecified
0.939 0.061 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.936 0.064 0.000
H04 Disorders of lachrymal system
0.936 0.064 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.936 0.064 0.000
L13 Other bullous disorders
0.933 0.067 0.000
D86.0 Sarcoidosis of lung
0.932 0.068 0.000
H06.2 Dysthyroid exophthalmos
0.931 0.069 0.000
E55.9 Vitamin D deficiency, unspecified
0.926 0.074 0.000
L72.1 Trichilemmal cyst
0.923 0.077 0.000
L13.0 Dermatitis herpetiformis
0.918 0.082 0.000
L27 Dermatitis due to substances taken internally
0.908 0.092 0.000
H04.8 Other disorders of lachrymal system
0.901 0.099 0.000
H33.4 Traction detachment of retina
0.899 0.101 0.000
L50-L54 Urticaria and erythema
0.898 0.102 0.000
E53 Deficiency of other B group vitamins
0.894 0.106 0.000
R31 Unspecified haematuria
0.000 0.107 0.893
H04.1 Other disorders of lachrymal gland
0.891 0.109 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.891 0.109 0.000
H31 Other disorders of choroid
0.887 0.113 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.876 0.124 0.000
H05 Disorders of orbit
0.874 0.126 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.873 0.127 0.000
K90 Intestinal malabsorption
0.872 0.128 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.870 0.130 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.869 0.131 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.869 0.131 0.000
D86.8 Sarcoidosis of other and combined sites
0.866 0.134 0.000
L70 Acne
0.866 0.134 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.861 0.139 0.000
E14.8 With unspecified complications
0.859 0.141 0.000
L21 Seborrhoeic dermatitis
0.855 0.145 0.000
L40-L45 Papulosquamous disorders
0.079 0.146 0.774
E14.6 With other specified complications
0.852 0.148 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.840 0.160 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.840 0.160 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.837 0.163 0.000
E40-E46 Malnutrition
0.837 0.163 0.000
H33.2 Serous retinal detachment
0.836 0.164 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.830 0.170 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.828 0.172 0.000
H31.0 Chorioretinal scars
0.824 0.176 0.000
K90.9 Intestinal malabsorption, unspecified
0.824 0.176 0.000
E10.0 With coma
0.820 0.180 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.804 0.196 0.000
E10.7 With multiple complications
0.803 0.197 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.802 0.198 0.000
E10.8 With unspecified complications
0.800 0.200 0.000
Q44.6 Cystic disease of liver
0.795 0.205 0.000
E63 Other nutritional deficiencies
0.793 0.207 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.792 0.208 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.789 0.211 0.000
E53.8 Deficiency of other specified B group vitamins
0.787 0.213 0.000
E14.2 Withrenal complications
0.783 0.217 0.000
H05.2 Exophthalmic conditions
0.782 0.218 0.000
L65 Other nonscarring hair loss
0.778 0.222 0.000
Chapter XXII Codes for special purposes
0.777 0.222 0.000
L71.8 Other rosacea
0.775 0.225 0.000
Q43 Other congenital malformations of intestine
0.774 0.226 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.773 0.227 0.000
L21.9 Seborrhoeic dermatitis, unspecified
0.772 0.228 0.000
M35 Other systemic involvement of connective tissue
0.772 0.228 0.000
M35.0 Sicca syndrome [Sjogren]
0.770 0.230 0.000
L51 Erythema multiforme
0.768 0.232 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.768 0.232 0.000
D86.1 Sarcoidosis of lymph nodes
0.766 0.234 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.765 0.235 0.000
L52 Erythema nodosum
0.764 0.236 0.000
E27.1 Primary adrenocortical insufficiency
0.763 0.237 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.761 0.239 0.000
L40.0 Psoriasis vulgaris
0.000 0.240 0.760
C34 Malignant neoplasm of bronchus and lung
0.759 0.241 0.000
L26 Exfoliative dermatitis
0.756 0.244 0.000
E20-E35 Disorders of other endocrine glands
0.756 0.244 0.000
L25 Unspecified contact dermatitis
0.756 0.244 0.000
E27 Other disorders of adrenal gland
0.756 0.244 0.000
C34.3 Lower lobe, bronchus or lung
0.753 0.247 0.000
D82 Immunodeficiency associated with other major defects
0.752 0.247 0.000
M35.3 Polymyalgia rheumatica
0.752 0.248 0.000
C34.9 Bronchus or lung, unspecified
0.751 0.249 0.000
L70.0 Acne vulgaris
0.751 0.249 0.000
L53 Other erythematous conditions
0.750 0.250 0.000
L23 Allergic contact dermatitis
0.750 0.250 0.000
D50.1 Sideropenic dysphagia
0.750 0.250 0.000
L30 Other dermatitis
0.748 0.252 0.000
E10.6 With other specified complications
0.748 0.252 0.000
D69 Purpura and other haemorrhagic conditions
0.746 0.254 0.000
L40.1 Generalised pustular psoriasis
0.000 0.257 0.743
Q66 Congenital deformities of feet
0.743 0.257 0.000
E54 Ascorbic acid deficiency
0.742 0.258 0.000
M35.1 Other overlap syndromes
0.741 0.259 0.000
D52 Folate deficiency anaemia
0.740 0.260 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.739 0.261 0.000
D55-D59 Haemolytic anaemias
0.738 0.262 0.000
E53.9 Vitamin B deficiency, unspecified
0.737 0.262 0.000
E14.5 With peripheral circulatory complications
0.737 0.263 0.000
H55-H59 Other disorders of eye and adnexa
0.736 0.264 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.732 0.268 0.000
L72.2 Steatocystoma multiplex
0.730 0.270 0.000
G36 Other acute disseminated demyelination
0.728 0.272 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.727 0.273 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.727 0.273 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.726 0.274 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.724 0.275 0.000
Q74 Other congenital malformations of limb(s)
0.724 0.276 0.000
Q65 Congenital deformities of hip
0.724 0.276 0.000
L10 Pemphigus
0.722 0.278 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.721 0.279 0.000
E46 Unspecified protein-energy malnutrition
0.720 0.280 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.720 0.280 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.718 0.282 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.718 0.282 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
D81 Combined immunodeficiencies
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.716 0.284 0.000
E00 Congenital iodine-deficiency syndrome
0.716 0.284 0.000
Q40 Other congenital malformations of upper alimentary tract
0.716 0.284 0.000
H16 Keratitis
0.716 0.284 0.000
L30.8 Other specified dermatitis
0.715 0.285 0.000
L40.8 Other psoriasis
0.000 0.285 0.715
H05.0 Acute inflammation of orbit
0.715 0.285 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.714 0.286 0.000
H46 Optic neuritis
0.714 0.286 0.000
L40.2 Acrodermatitis continua
0.000 0.287 0.713
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.713 0.287 0.000
L42 Pityriasis rosea
0.034 0.288 0.678
H00 Hordeolum and chalazion
0.710 0.290 0.000
G37.5 Concentric sclerosis [Balo]
0.708 0.292 0.000
G37.4 Subacute necrotising myelitis
0.708 0.292 0.000
G37.2 Central pontine myelinolysis
0.708 0.292 0.000
G37.1 Central demyelination of corpus callosum
0.708 0.292 0.000
G37.0 Diffuse sclerosis
0.708 0.292 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.708 0.292 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.707 0.293 0.000
E50 Vitamin A deficiency
0.707 0.293 0.000
E60 Dietary zinc deficiency
0.707 0.293 0.000
E59 Dietary selenium deficiency
0.707 0.293 0.000
E52 Niacin deficiency [pellagra]
0.707 0.293 0.000
L75 Apocrine sweat disorders
0.706 0.293 0.000
L74 Eccrine sweat disorders
0.706 0.293 0.000
L67 Hair colour and hair shaft abnormalities
0.706 0.293 0.000
L64 Androgenic alopecia
0.706 0.293 0.000
L62 Nail disorders in diseases classified elsewhere
0.706 0.293 0.000
L40.4 Guttate psoriasis
0.000 0.294 0.705
Chapter II Neoplasms
0.703 0.297 0.000
Q35-Q37 Cleft lip and cleft palate
0.703 0.297 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.698 0.302 0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.698 0.302 0.000
D84 Other immunodeficiencies
0.697 0.303 0.000
D53 Other nutritional anaemias
0.697 0.303 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.303 0.696
L24 Irritant contact dermatitis
0.696 0.304 0.000
L22 Diaper [napkin] dermatitis
0.696 0.304 0.000
E51 Thiamine deficiency
0.696 0.304 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.695 0.305 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.694 0.306 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.693 0.307 0.000
C88 Malignant immunoproliferative diseases
0.691 0.309 0.000
L71.0 Perioral dermatitis
0.690 0.310 0.000
H18 Other disorders of cornea
0.685 0.315 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.685 0.315 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.685 0.315 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.685 0.315 0.000
D86.3 Sarcoidosis of skin
0.684 0.316 0.000
L14 Bullous disorders in diseases classified elsewhere
0.684 0.316 0.000
E61 Deficiency of other nutrient elements
0.684 0.316 0.000
L70.9 Acne, unspecified
0.683 0.317 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.682 0.318 0.000
E55.0 Rickets, active
0.682 0.318 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.681 0.319 0.000
L51.9 Erythema multiforme, unspecified
0.681 0.319 0.000
D51.2 Transcobalamin II deficiency
0.681 0.319 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.681 0.319 0.000
L71.1 Rhinophyma
0.681 0.319 0.000
D80 Immunodeficiency with predominantly antibody defects
0.679 0.321 0.000
Q78 Other osteochondrodysplasias
0.679 0.321 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.678 0.322 0.000
L63 Alopecia areata
0.678 0.322 0.000
D83 Common variable immunodeficiency
0.677 0.323 0.000
U88 Agent resistant to multiple antibiotics
0.675 0.325 0.000
E56 Other vitamin deficiencies
0.675 0.325 0.000
E14.1 With ketoacidosis
0.675 0.325 0.000
H30 Chorioretinal inflammation
0.673 0.326 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.672 0.327 0.001
M06.9 Rheumatoid arthritis, unspecified
0.000 0.329 0.671
M06 Other rheumatoid arthritis
0.001 0.330 0.669
M35.7 Hypermobility syndrome
0.670 0.330 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.669 0.331 0.000
L13.9 Bullous disorder, unspecified
0.669 0.331 0.000
L13.8 Other specified bullous disorders
0.669 0.331 0.000
L13.1 Subcorneal pustular dermatitis
0.669 0.331 0.000
L27.2 Dermatitis due to ingested food
0.669 0.331 0.000
L53.8 Other specified erythematous conditions
0.669 0.331 0.000
H33.1 Retinoschisis and retinal cysts
0.667 0.333 0.000
L11 Other acantholytic disorders
0.666 0.334 0.000
E58 Dietary calcium deficiency
0.665 0.335 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.664 0.336 0.000
H53-H54 Visual disturbances and blindness
0.662 0.338 0.000
L68 Hypertrichosis
0.659 0.341 0.000
L20 Atopic dermatitis
0.658 0.342 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.658 0.342 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.344 0.656
H55 Nystagmus and other irregular eye movements
0.654 0.346 0.000
E63.9 Nutritional deficiency, unspecified
0.654 0.346 0.000
C34.0 Main bronchus
0.654 0.346 0.000
D59 Acquired haemolytic anaemia
0.652 0.348 0.000
Q79.6 Ehlers-Danlos syndrome
0.652 0.348 0.000
L27.9 Dermatitis due to unspecified substance taken internally
0.651 0.349 0.000
L27.8 Dermatitis due to other substances taken internally
0.651 0.349 0.000
H04.0 Dacryoadenitis
0.650 0.350 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.648 0.352 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.648 0.352 0.000
C91 Lymphoid leukaemia
0.647 0.353 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.646 0.354 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.646 0.354 0.000
L54 Erythema in diseases classified elsewhere
0.644 0.356 0.000
Q43.8 Other specified congenital malformations of intestine
0.644 0.356 0.000
E13 Other specified diabetes mellitus
0.644 0.356 0.000
H05.8 Other disorders of orbit
0.643 0.357 0.000
H31.9 Disorder of choroid, unspecified
0.642 0.357 0.000
E53.1 Pyridoxine deficiency
0.641 0.359 0.000
E53.0 Riboflavin deficiency
0.641 0.359 0.000
Q00-Q07 Congenital malformations of the nervous system
0.640 0.359 0.000
H17 Corneal scars and opacities
0.640 0.360 0.000
E27.2 Addisonian crisis
0.639 0.361 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.639 0.361 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.639 0.361 0.000
Chapter I Certain infectious and parasitic diseases
0.638 0.362 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.638 0.362 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.638 0.362 0.000
H31.4 Choroidal detachment
0.636 0.364 0.000
H31.2 Hereditary choroidal dystrophy
0.636 0.364 0.000
H47.3 Other disorders of optic disk
0.636 0.364 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.635 0.365 0.000
M06.3 Rheumatoid nodule
0.000 0.366 0.634
Q39 Congenital malformations of oesophagus
0.633 0.367 0.000
H04.6 Other changes in lachrymal passages
0.633 0.367 0.000
M05-M14 Inflammatory polyarthropathies
0.016 0.368 0.616
H18.6 Keratoconus
0.632 0.368 0.000
H31.8 Other specified disorders of choroid
0.630 0.370 0.000
L65.9 Nonscarring hair loss, unspecified
0.630 0.370 0.000
C83.0 Small cell (diffuse)
0.628 0.372 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.628 0.372 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.628 0.372 0.000
Q75 Other congenital malformations of skull and face bones
0.628 0.372 0.000
Q73 Reduction defects of unspecified limb
0.628 0.372 0.000
Q72 Reduction defects of lower limb
0.628 0.372 0.000
Q71 Reduction defects of upper limb
0.628 0.372 0.000
Q70 Syndactyly
0.628 0.372 0.000
Q69 Polydactyly
0.628 0.372 0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.626 0.373 0.000
H05.3 Deformity of orbit
0.626 0.373 0.000
C91.1 Chronic lymphocytic leukaemia
0.626 0.374 0.000
K90.3 Pancreatic steatorrhoea
0.625 0.375 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.625 0.375 0.000
K90.1 Tropical sprue
0.625 0.375 0.000
H31.3 Choroidal haemorrhage and rupture
0.625 0.375 0.000
D89.3 Immune reconstitution syndrome
0.624 0.376 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.623 0.377 0.000
M05 Seropositive rheumatoid arthritis
0.006 0.378 0.617
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.378 0.622
L70.8 Other acne
0.621 0.379 0.000
L70.5 Acne excoriee des jeunes filles
0.621 0.379 0.000
L70.4 Infantile acne
0.621 0.379 0.000
L70.3 Acne tropica
0.621 0.379 0.000
L70.2 Acne varioliformis
0.621 0.379 0.000
L70.1 Acne conglobata
0.621 0.379 0.000
H05.9 Disorder of orbit, unspecified
0.620 0.380 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.620 0.380 0.000
L30.0 Nummular dermatitis
0.620 0.380 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.380 0.619
M06.0 Seronegative rheumatoid arthritis
0.000 0.381 0.619
C34.2 Middle lobe, bronchus or lung
0.618 0.382 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.616 0.383 0.000
Q66.8 Other congenital deformities of feet
0.617 0.383 0.000
L28 Lichen simplex chronicus and prurigo
0.616 0.383 0.000
H25-H28 Disorders of lens
0.615 0.385 0.000
H05.4 Enophthalmos
0.614 0.386 0.000
L21.8 Other seborrhoeic dermatitis
0.613 0.387 0.000
L21.1 Seborrhoeic infantile dermatitis
0.613 0.387 0.000
L21.0 Seborrhoea capitis
0.613 0.387 0.000
L44 Other papulosquamous disorders
0.057 0.388 0.555
L45 Papulosquamous disorders in diseases classified elsewhere
0.057 0.388 0.555
L29 Pruritus
0.612 0.388 0.000
L53.0 Toxic erythema
0.611 0.389 0.000
D67 Hereditary factor IX deficiency
0.611 0.389 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.610 0.390 0.000
H15 Disorders of sclera
0.610 0.390 0.000
H16.0 Corneal ulcer
0.609 0.391 0.000
B00 Herpesviral [herpes simplex] infections
0.607 0.393 0.000
D69.5 Secondary thrombocytopenia
0.606 0.394 0.000
Q74.1 Congenital malformation of knee
0.605 0.395 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.604 0.396 0.000
L25.9 Unspecified contact dermatitis, unspecified cause
0.603 0.397 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.601 0.398 0.000
Q44.4 Choledochal cyst
0.601 0.399 0.000
Q68 Other congenital musculoskeletal deformities
0.601 0.399 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.600 0.400 0.000
E45 Retarded development following protein-energy malnutrition
0.600 0.400 0.000
E43 Unspecified severe protein-energy malnutrition
0.600 0.400 0.000
E42 Marasmic kwashiorkor
0.600 0.400 0.000
E41 Nutritional marasmus
0.600 0.400 0.000
E40 Kwashiorkor
0.600 0.400 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.600 0.400 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.600 0.400 0.000
E20 Hypoparathyroidism
0.600 0.400 0.000
L41 Parapsoriasis
0.057 0.401 0.541
C34.8 Overlapping lesion of bronchus and lung
0.598 0.402 0.000
K90.8 Other intestinal malabsorption
0.598 0.402 0.000
Q27 Other congenital malformations of peripheral vascular system
0.597 0.403 0.000
Q43.3 Congenital malformations of intestinal fixation
0.596 0.404 0.000
B01 Varicella [chickenpox]
0.595 0.404 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.595 0.405 0.000
Q44.2 Atresia of bile ducts
0.595 0.405 0.000
Q44.1 Other congenital malformations of gallbladder
0.595 0.405 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.595 0.405 0.000
E07 Other disorders of thyroid
0.595 0.405 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.595 0.405 0.000
H01 Other inflammation of eyelid
0.595 0.405 0.000
D59.1 Other autoimmune haemolytic anaemias
0.594 0.406 0.000
C84.5 Other and unspecified T-cell lymphomas
0.591 0.409 0.000
Q66.3 Other congenital varus deformities of feet
0.589 0.411 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.589 0.411 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.412 0.588
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.588 0.412 0.000
L43 Lichen planus
0.028 0.414 0.558
L23.1 Allergic contact dermatitis due to adhesives
0.586 0.414 0.000
H31.1 Choroidal degeneration
0.583 0.417 0.000
Q65.0 Congenital dislocation of hip, unilateral
0.583 0.417 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.419 0.581
Q44.7 Other congenital malformations of liver
0.581 0.419 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.581 0.419 0.000
Q96 Turner's syndrome
0.579 0.421 0.000
D69.4 Other primary thrombocytopenia
0.578 0.422 0.000
Q23 Congenital malformations of aortic and mitral valves
0.578 0.422 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.578 0.422 0.000
H54 Blindness and low vision
0.577 0.423 0.000
Q60-Q64 Congenital malformations of the urinary system
0.576 0.424 0.000
B00.5 Herpesviral ocular disease
0.576 0.424 0.000
Q31 Congenital malformations of larynx
0.576 0.424 0.000
H26 Other cataract
0.576 0.424 0.000
D82.1 Di George's syndrome
0.575 0.425 0.000
C64-C68 Malignant neoplasms of urinary tract
0.575 0.425 0.000
C92 Myeloid leukaemia
0.575 0.425 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.427 0.573
G14 Postpolio syndrome
0.573 0.427 0.000
M20-M25 Other joint disorders
0.572 0.428 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.009 0.428 0.563
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.572 0.428 0.000
H26.4 After-cataract
0.570 0.430 0.000
C84.0 Mycosis fungoides
0.570 0.430 0.000
Q35 Cleft palate
0.569 0.430 0.000
M07 Psoriatic and enteropathic arthropathies
0.008 0.431 0.562
E05.8 Other thyrotoxicosis
0.569 0.431 0.000
E63.8 Other specified nutritional deficiencies
0.568 0.432 0.000
E63.1 Imbalance of constituents of food intake
0.568 0.432 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.568 0.432 0.000
Q66.6 Other congenital valgus deformities of feet
0.567 0.432 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.433 0.567
E34 Other endocrine disorders
0.567 0.433 0.000
Q40.2 Other specified congenital malformations of stomach
0.566 0.434 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.565 0.435 0.000
H18.5 Hereditary corneal dystrophies
0.565 0.435 0.000
Q66.0 Talipes equinovarus
0.564 0.436 0.000
D69.8 Other specified haemorrhagic conditions
0.564 0.436 0.000
L10.0 Pemphigus vulgaris
0.563 0.436 0.000
H16.3 Interstitial and deep keratitis
0.563 0.437 0.000
D89.1 Cryoglobulinaemia
0.562 0.438 0.000
E31 Polyglandular dysfunction
0.562 0.438 0.000
L30.1 Dyshidrosis [pompholyx]
0.562 0.438 0.000
M86-M90 Other osteopathies
0.562 0.438 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.560 0.439 0.000
Q65.8 Other congenital deformities of hip
0.560 0.440 0.000
Q17 Other congenital malformations of ear
0.560 0.440 0.000
C84.4 Peripheral T-cell lymphoma
0.560 0.440 0.000
C81 Hodgkin's disease
0.559 0.441 0.000
E14.4 With neurological complications
0.558 0.441 0.000
L65.8 Other specified nonscarring hair loss
0.558 0.442 0.000
L65.2 Alopecia mucinosa
0.558 0.442 0.000
L65.1 Anagen effluvium
0.558 0.442 0.000
L65.0 Telogen effluvium
0.558 0.442 0.000
Q44.5 Other congenital malformations of bile ducts
0.556 0.443 0.000
G30-G32 Other degenerative diseases of the nervous system
0.556 0.444 0.000
D69.2 Other nonthrombocytopenic purpura
0.555 0.445 0.000
L23.5 Allergic contact dermatitis due to other chemical products
0.555 0.445 0.000
Q43.7 Persistent cloaca
0.555 0.445 0.000
Q43.6 Congenital fistula of rectum and anus
0.555 0.445 0.000
Q43.5 Ectopic anus
0.555 0.445 0.000
Q43.4 Duplication of intestine
0.555 0.445 0.000
Q43.2 Other congenital functional disorders of colon
0.555 0.445 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.446 0.554
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere
0.554 0.446 0.000
B07 Viral warts
0.554 0.446 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.554 0.446 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.553 0.446 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.553 0.446 0.000
M35.5 Multifocal fibrosclerosis
0.553 0.446 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.553 0.446 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.447 0.553
D52.9 Folate deficiency anaemia, unspecified
0.553 0.447 0.000
A30-A49 Other bacterial diseases
0.552 0.448 0.000
E04 Other non-toxic goitre
0.551 0.449 0.000
L51.8 Other erythema multiforme
0.551 0.449 0.000
L51.2 Toxic epidermal necrolysis [Lyell]
0.551 0.449 0.000
L51.0 Nonbullous erythema multiforme
0.551 0.449 0.000
H18.1 Bullous keratopathy
0.551 0.449 0.000
H54.9 Unspecified visual impairment (binocular)
0.550 0.450 0.000
C67 Malignant neoplasm of bladder
0.550 0.450 0.000
H04.9 Disorder of lachrymal system, unspecified
0.549 0.450 0.000
M35.8 Other specified systemic involvement of connective tissue
0.549 0.451 0.000
Q14 Congenital malformations of posterior segment of eye
0.549 0.451 0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.548 0.451 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.548 0.451 0.000
Q66.7 Pes cavus
0.548 0.452 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.547 0.453 0.000
G82 Paraplegia and tetraplegia
0.547 0.453 0.000
L66.1 Lichen planopilaris
0.546 0.454 0.000
C31 Malignant neoplasm of accessory sinuses
0.545 0.454 0.000
Q43.1 Hirschsprung's disease
0.545 0.455 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.545 0.455 0.000
H16.4 Corneal neovascularisation
0.544 0.456 0.000
C93 Monocytic leukaemia
0.543 0.457 0.000
Q67.6 Pectus excavatum
0.542 0.457 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.542 0.458 0.000
E32 Diseases of thymus
0.542 0.458 0.000
E30 Disorders of puberty, not elsewhere classified
0.542 0.458 0.000
L25.8 Unspecified contact dermatitis due to other agents
0.542 0.458 0.000
L25.5 Unspecified contact dermatitis due to plants, except food
0.542 0.458 0.000
L25.4 Unspecified contact dermatitis due to food in contact with the skin
0.542 0.458 0.000
L25.3 Unspecified contact dermatitis due to other chemical products
0.542 0.458 0.000
L25.2 Unspecified contact dermatitis due to dyes
0.542 0.458 0.000
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin
0.542 0.458 0.000
L25.0 Unspecified contact dermatitis due to cosmetics
0.542 0.458 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.542 0.458 0.000
E27.5 Adrenomedullary hyperfunction
0.542 0.458 0.000
E27.0 Other adrenocortical overactivity
0.542 0.458 0.000
M00-M03 Infectious arthropathies
0.541 0.459 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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