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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34145779
log Bayes Factor = 7.00229
Chromosome 13   position 89,636,306  (GRCh37) Explore rs34145779 on Ensembl!
Variant rs34145779 is part of Cluster X0332

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.991 0.009 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.990 0.010 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.987 0.013 0.000
O00-O08 Pregnancy with abortive outcome
0.984 0.016 0.000
M80-M85 Disorders of bone density and structure
0.984 0.016 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.978 0.022 0.000
D50-D53 Nutritional anaemias
0.977 0.023 0.000
S00-S09 Injuries to the head
0.974 0.026 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.970 0.030 0.000
M65-M68 Disorders of synovium and tendon
0.968 0.032 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.967 0.033 0.000
E20-E35 Disorders of other endocrine glands
0.963 0.037 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.961 0.039 0.000
O02 Other abnormal products of conception
0.958 0.042 0.000
S50-S59 Injuries to the elbow and forearm
0.957 0.043 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.956 0.044 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.953 0.047 0.000
M05 Seropositive rheumatoid arthritis
0.948 0.052 0.000
Chapter VIII Diseases of the ear and mastoid process
0.945 0.055 0.000
D50 Iron deficiency anaemia
0.942 0.058 0.000
S00 Superficial injury of head
0.940 0.060 0.000
O02.1 Missed abortion
0.938 0.062 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.937 0.063 0.000
M80 Osteoporosis with pathological fracture
0.933 0.067 0.000
E21.3 Hyperparathyroidism, unspecified
0.930 0.070 0.000
M65 Synovitis and tenosynovitis
0.927 0.073 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.925 0.075 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.923 0.077 0.000
D51 Vitamin B12 deficiency anaemia
0.922 0.078 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.920 0.080 0.000
O20 Haemorrhage in early pregnancy
0.920 0.080 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.916 0.084 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.911 0.089 0.000
Chapter XX External causes of morbidity and mortality
0.909 0.091 0.000
H90-H95 Other disorders of ear
0.904 0.096 0.000
M81 Osteoporosis without pathological fracture
0.904 0.096 0.000
R40 Somnolence, stupor and coma
0.902 0.098 0.000
S01 Open wound of head
0.902 0.098 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.902 0.098 0.000
R25 Abnormal involuntary movements
0.901 0.099 0.000
M06.3 Rheumatoid nodule
0.900 0.100 0.000
R20 Disturbances of skin sensation
0.899 0.101 0.000
D50.8 Other iron deficiency anaemias
0.899 0.101 0.000
R21 Rash and other nonspecific skin eruption
0.895 0.105 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.895 0.105 0.000
E27 Other disorders of adrenal gland
0.892 0.108 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.888 0.112 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.884 0.116 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.883 0.117 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.882 0.118 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.877 0.123 0.000
S90-S99 Injuries to the ankle and foot
0.874 0.126 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.874 0.126 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.872 0.128 0.000
M86-M90 Other osteopathies
0.870 0.130 0.000
E21.0 Primary hyperparathyroidism
0.870 0.130 0.000
S51 Open wound of forearm
0.869 0.131 0.000
S00.1 Contusion of eyelid and periocular area
0.867 0.133 0.000
R25.2 Cramp and spasm
0.866 0.134 0.000
R73 Elevated blood glucose level
0.866 0.134 0.000
R40.2 Coma, unspecified
0.865 0.135 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.862 0.138 0.000
H90 Conductive and sensorineural hearing loss
0.862 0.138 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.859 0.141 0.000
R27 Other lack of coordination
0.859 0.141 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.853 0.147 0.000
D50.9 Iron deficiency anaemia, unspecified
0.851 0.149 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.850 0.150 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.849 0.151 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.849 0.151 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.846 0.154 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.846 0.154 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.845 0.155 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.842 0.158 0.000
R73.9 Hyperglycaemia, unspecified
0.840 0.160 0.000
S52 Fracture of forearm
0.837 0.163 0.000
W20-W49 Exposure to inanimate mechanical forces
0.832 0.168 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.830 0.170 0.000
M81.9 Osteoporosis, unspecified
0.825 0.175 0.000
M67 Other disorders of synovium and tendon
0.825 0.175 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.824 0.176 0.000
S00.5 Superficial injury of lip and oral cavity
0.814 0.186 0.000
O04 Medical abortion
0.811 0.189 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.811 0.189 0.000
O23 Infections of genito-urinary tract in pregnancy
0.811 0.189 0.000
H90.2 Conductive hearing loss, unspecified
0.810 0.190 0.000
R40.0 Somnolence
0.809 0.191 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.803 0.197 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.802 0.198 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.797 0.203 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.795 0.205 0.000
M84 Disorders of continuity of bone
0.795 0.205 0.000
Chapter I Certain infectious and parasitic diseases
0.795 0.205 0.000
O85-O92 Complications predominantly related to the puerperium
0.793 0.206 0.000
D80-D89 Certain disorders involving the immune mechanism
0.793 0.207 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.791 0.209 0.000
R27.0 Ataxia, unspecified
0.789 0.211 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.789 0.211 0.000
O03 Spontaneous abortion
0.788 0.212 0.000
R76 Other abnormal immunological findings in serum
0.786 0.214 0.000
H90.0 Conductive hearing loss, bilateral
0.785 0.215 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.783 0.217 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.782 0.218 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.780 0.220 0.000
O22 Venous complications in pregnancy
0.778 0.222 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.777 0.223 0.000
T66-T78 Other and unspecified effects of external causes
0.776 0.224 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.775 0.225 0.000
H92 Otalgia and effusion of ear
0.774 0.226 0.000
S00.0 Superficial injury of scalp
0.774 0.226 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.772 0.228 0.000
M91-M94 Chondropathies
0.771 0.229 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.771 0.229 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.770 0.230 0.000
S51.8 Open wound of other parts of forearm
0.767 0.233 0.000
E27.1 Primary adrenocortical insufficiency
0.765 0.235 0.000
H65-H75 Diseases of middle ear and mastoid
0.765 0.235 0.000
M11 Other crystal arthropathies
0.764 0.236 0.000
M06.4 Inflammatory polyarthropathy
0.763 0.237 0.000
S09 Other and unspecified injuries of head
0.762 0.238 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.760 0.240 0.000
E40-E46 Malnutrition
0.759 0.241 0.000
S01.5 Open wound of lip and oral cavity
0.759 0.241 0.000
M86 Osteomyelitis
0.756 0.244 0.000
T82.3 Mechanical complication of other vascular grafts
0.755 0.245 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.754 0.246 0.000
M60-M63 Disorders of muscles
0.754 0.246 0.000
H60-H62 Diseases of external ear
0.754 0.246 0.000
M40-M43 Deforming dorsopathies
0.753 0.247 0.000
Q80-Q89 Other congenital malformations
0.753 0.247 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.752 0.248 0.000
S01.7 Multiple open wounds of head
0.752 0.248 0.000
E26 Hyperaldosteronism
0.752 0.248 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.750 0.250 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.750 0.250 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.750 0.250 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.748 0.252 0.000
O80-O84 Delivery
0.747 0.253 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.747 0.253 0.000
W50-W64 Exposure to animate mechanical forces
0.746 0.254 0.000
M81.2 Osteoporosis of disuse
0.746 0.254 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.743 0.257 0.000
E22 Hyperfunction of pituitary gland
0.743 0.257 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.741 0.259 0.000
S01.8 Open wound of other parts of head
0.740 0.260 0.000
R74 Abnormal serum enzyme levels
0.740 0.260 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.740 0.260 0.000
O00 Ectopic pregnancy
0.737 0.262 0.000
S50 Superficial injury of forearm
0.736 0.264 0.000
M14 Arthropathies in other diseases classified elsewhere
0.734 0.265 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.733 0.267 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.730 0.270 0.000
T18 Foreign body in alimentary tract
0.730 0.270 0.000
M65.3 Trigger finger
0.730 0.270 0.000
T21 Burn and corrosion of trunk
0.730 0.270 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.729 0.271 0.000
S91 Open wound of ankle and foot
0.728 0.272 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.727 0.273 0.000
E00-E07 Disorders of thyroid gland
0.727 0.273 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.725 0.275 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.724 0.275 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.724 0.276 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.722 0.278 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.722 0.278 0.000
D55-D59 Haemolytic anaemias
0.721 0.279 0.000
S52.6 Fracture of lower end of both ulna and radius
0.720 0.280 0.000
M67.1 Other contracture of tendon (sheath)
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.716 0.284 0.000
W22 Striking against or struck by other objects
0.715 0.285 0.000
M06.34 Rheumatoid nodule (Hand)
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.713 0.287 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.712 0.288 0.000
S00.7 Multiple superficial injuries of head
0.711 0.289 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.711 0.289 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.710 0.290 0.000
R77 Other abnormalities of plasma proteins
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.707 0.293 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.706 0.293 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.706 0.294 0.000
W21 Striking against or struck by sports equipment
0.706 0.294 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.705 0.295 0.000
O07 Failed attempted abortion
0.705 0.295 0.000
O06 Unspecified abortion
0.705 0.295 0.000
O05 Other abortion
0.705 0.295 0.000
O01 Hydatidiform mole
0.705 0.295 0.000
M83 Adult osteomalacia
0.705 0.295 0.000
M82 Osteoporosis in diseases classified elsewhere
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.704 0.296 0.000
A30-A49 Other bacterial diseases
0.703 0.297 0.000
S56 Injury of muscle and tendon at forearm level
0.703 0.297 0.000
S01.2 Open wound of nose
0.703 0.297 0.000
O21 Excessive vomiting in pregnancy
0.703 0.297 0.000
S01.3 Open wound of ear
0.701 0.299 0.000
D53 Other nutritional anaemias
0.700 0.300 0.000
S10-S19 Injuries to the neck
0.699 0.301 0.000
S92 Fracture of foot, except ankle
0.699 0.301 0.000
S08 Traumatic amputation of part of head
0.698 0.302 0.000
S07 Crushing injury of head
0.698 0.302 0.000
S04 Injury of cranial nerves
0.698 0.302 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.698 0.302 0.000
S51.7 Multiple open wounds of forearm
0.698 0.302 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.698 0.302 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.696 0.304 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.696 0.304 0.000
Q50-Q56 Congenital malformations of genital organs
0.696 0.304 0.000
O29 Complications of anaesthesia during pregnancy
0.696 0.304 0.000
O28 Abnormal findings on antenatal screening of mother
0.696 0.304 0.000
O25 Malnutrition in pregnancy
0.696 0.304 0.000
M81.98 Osteoporosis, unspecified (Other)
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.695 0.305 0.000
S80-S89 Injuries to the knee and lower leg
0.694 0.306 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.694 0.306 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.693 0.307 0.000
R41.3 Other amnesia
0.693 0.307 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.690 0.310 0.000
E34 Other endocrine disorders
0.690 0.310 0.000
E32 Diseases of thymus
0.690 0.310 0.000
E31 Polyglandular dysfunction
0.690 0.310 0.000
E30 Disorders of puberty, not elsewhere classified
0.690 0.310 0.000
E25 Adrenogenital disorders
0.690 0.310 0.000
E20 Hypoparathyroidism
0.690 0.310 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.689 0.311 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.689 0.311 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.689 0.311 0.000
O20.8 Other haemorrhage in early pregnancy
0.689 0.311 0.000
O04.9 Complete or unspecified, without complication
0.688 0.312 0.000
R76.8 Other specified abnormal immunological findings in serum
0.688 0.312 0.000
O02.9 Abnormal product of conception, unspecified
0.687 0.313 0.000
O02.8 Other specified abnormal products of conception
0.687 0.313 0.000
S59 Other and unspecified injuries of forearm
0.686 0.314 0.000
S58 Traumatic amputation of forearm
0.686 0.314 0.000
S57 Crushing injury of forearm
0.686 0.314 0.000
S55 Injury of blood vessels at forearm level
0.686 0.314 0.000
S54 Injury of nerves at forearm level
0.686 0.314 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.686 0.314 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.686 0.314 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.686 0.314 0.000
O14.9 Preeclampsia, unspecified
0.685 0.314 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.685 0.315 0.000
S06 Intracranial injury
0.685 0.315 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.685 0.315 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.684 0.316 0.000
E24 Cushing's syndrome
0.684 0.316 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.683 0.317 0.000
E21.4 Other specified disorders of parathyroid gland
0.683 0.317 0.000
E21.2 Other hyperparathyroidism
0.683 0.317 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.683 0.317 0.000
M65.1 Other infective (teno)synovitis
0.683 0.317 0.000
B15-B19 Viral hepatitis
0.682 0.318 0.000
D75 Other diseases of blood and blood-forming organs
0.681 0.319 0.000
O03.9 Complete or unspecified, without complication
0.680 0.320 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.680 0.320 0.000
T86 Failure and rejection of transplanted organs and tissues
0.680 0.320 0.000
M05.8 Other seropositive rheumatoid arthritis
0.680 0.320 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.680 0.320 0.000
M05.2 Rheumatoid vasculitis
0.680 0.320 0.000
M05.1 Rheumatoid lung disease
0.680 0.320 0.000
M05.0 Felty's syndrome
0.680 0.320 0.000
T85.2 Mechanical complication of intraocular lens
0.680 0.320 0.000
D86 Sarcoidosis
0.679 0.321 0.000
S52.3 Fracture of shaft of radius
0.679 0.321 0.000
R23 Other skin changes
0.679 0.321 0.000
H93 Other disorders of ear, not elsewhere classified
0.679 0.321 0.000
M66 Spontaneous rupture of synovium and tendon
0.678 0.321 0.000
H92.1 Otorrhoea
0.678 0.322 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.678 0.322 0.000
M89 Other disorders of bone
0.677 0.323 0.000
D52 Folate deficiency anaemia
0.677 0.323 0.000
Y40 Systemic antibiotics
0.677 0.323 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.676 0.324 0.000
D50.1 Sideropenic dysphagia
0.676 0.324 0.000
M86.9 Osteomyelitis, unspecified
0.675 0.325 0.000
E27.2 Addisonian crisis
0.674 0.325 0.000
S00.4 Superficial injury of ear
0.674 0.326 0.000
T79-T79 Certain early complications of trauma
0.674 0.326 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.673 0.327 0.000
S00.8 Superficial injury of other parts of head
0.672 0.328 0.000
E07 Other disorders of thyroid
0.671 0.329 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.671 0.329 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.670 0.330 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.669 0.331 0.000
M80.8 Other osteoporosis with pathological fracture
0.669 0.331 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.669 0.331 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.669 0.331 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.669 0.331 0.000
S01.9 Open wound of head, part unspecified
0.669 0.331 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.668 0.332 0.000
E50-E64 Other nutritional deficiencies
0.666 0.334 0.000
E27.9 Disorder of adrenal gland, unspecified
0.666 0.334 0.000
V20-V29 Motorcycle rider injured in transport accident
0.666 0.334 0.000
M65.2 Calcific tendinitis
0.665 0.335 0.000
M65.0 Abscess of tendon sheath
0.665 0.335 0.000
S52.4 Fracture of shafts of both ulna and radius
0.664 0.335 0.000
R27.8 Other and unspecified lack of coordination
0.664 0.335 0.000
V40-V49 Car occupant injured in transport accident
0.662 0.337 0.000
R71 Abnormality of red blood cells
0.662 0.338 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.662 0.338 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.662 0.338 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.661 0.339 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.661 0.339 0.000
D51.2 Transcobalamin II deficiency
0.661 0.339 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.661 0.339 0.000
M90 Osteopathies in diseases classified elsewhere
0.661 0.339 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.661 0.339 0.000
R43 Disturbances of smell and taste
0.660 0.340 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.657 0.343 0.000
T87 Complications peculiar to reattachment and amputation
0.656 0.344 0.000
M06.0 Seronegative rheumatoid arthritis
0.655 0.345 0.000
M65.8 Other synovitis and tenosynovitis
0.655 0.345 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.654 0.346 0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.654 0.346 0.000
W00-W19 Falls
0.654 0.346 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.653 0.346 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.653 0.346 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.653 0.346 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.653 0.346 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.653 0.346 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.653 0.346 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.653 0.346 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.653 0.346 0.000
Y35-Y36 Legal intervention and operations of war
0.652 0.348 0.000
Y10-Y34 Event of undetermined intent
0.652 0.348 0.000
X85-X99 Assault
0.652 0.348 0.000
X30-X39 Exposure to forces of nature
0.652 0.348 0.000
X10-X19 Contact with heat and hot substances
0.652 0.348 0.000
X00-X09 Exposure to smoke, fire and flames
0.652 0.348 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.652 0.348 0.000
W75-W84 Other accidental threats to breathing
0.652 0.348 0.000
W65-W74 Accidental drowning and submersion
0.652 0.348 0.000
V98-V99 Other and unspecified transport accidents
0.652 0.348 0.000
V95-V97 Air and space transport accidents
0.652 0.348 0.000
V90-V94 Water transport accidents
0.652 0.348 0.000
V70-V79 Bus occupant injured in transport accident
0.652 0.348 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.652 0.348 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.652 0.348 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.652 0.348 0.000
V01-V09 Pedestrian injured in transport accident
0.652 0.348 0.000
M85 Other disorders of bone density and structure
0.651 0.348 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.651 0.349 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.651 0.349 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.651 0.349 0.000
R25.1 Tremor, unspecified
0.650 0.350 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.650 0.350 0.000
S90 Superficial injury of ankle and foot
0.650 0.350 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.648 0.352 0.000
M81.8 Other osteoporosis
0.648 0.352 0.000
M81.6 Localised osteoporosis [Lequesne]
0.648 0.352 0.000
M81.5 Idiopathic osteoporosis
0.648 0.352 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.648 0.352 0.000
M81.1 Postoophorectomy osteoporosis
0.648 0.352 0.000
M81.0 Postmenopausal osteoporosis
0.648 0.352 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.647 0.352 0.000
T18.1 Foreign body in oesophagus
0.647 0.353 0.000
R40.1 Stupor
0.647 0.353 0.000
S52.5 Fracture of lower end of radius
0.647 0.353 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.646 0.354 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.646 0.354 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.646 0.354 0.000
T21.0 Burn of unspecified degree of trunk
0.646 0.354 0.000
W44 Foreign body entering into or through eye or natural orifice
0.646 0.354 0.000
R25.3 Fasciculation
0.646 0.354 0.000
R25.0 Abnormal head movements
0.646 0.354 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.646 0.354 0.000
M06.38 Rheumatoid nodule (Other)
0.646 0.354 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.646 0.354 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.646 0.354 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.646 0.354 0.000
M06.33 Rheumatoid nodule (Forearm)
0.646 0.354 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.646 0.354 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.646 0.354 0.000
X50-X57 Overexertion, travel and privation
0.645 0.354 0.000
X20-X29 Contact with venomous animals and plants
0.645 0.355 0.000
R20.3 Hyperaesthesia
0.645 0.355 0.000
R20.1 Hypoaesthesia of skin
0.645 0.355 0.000
R20.0 Anaesthesia of skin
0.645 0.355 0.000
H74 Other disorders of middle ear and mastoid
0.644 0.356 0.000
M45-M49 Spondylopathies
0.644 0.356 0.000
O24 Diabetes mellitus in pregnancy
0.642 0.357 0.000
Y43 Primarily systemic agents
0.643 0.357 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.641 0.358 0.000
Q35-Q37 Cleft lip and cleft palate
0.641 0.358 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.641 0.358 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.641 0.359 0.000
S99 Other and unspecified injuries of ankle and foot
0.640 0.360 0.000
E27.5 Adrenomedullary hyperfunction
0.640 0.360 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.640 0.360 0.000
E27.0 Other adrenocortical overactivity
0.640 0.360 0.000
S51.0 Open wound of elbow
0.640 0.360 0.000
O22.0 Varicose veins of lower extremity in pregnancy
0.640 0.360 0.000
T68 Hypothermia
0.640 0.360 0.000
M95.0 Acquired deformity of nose
0.639 0.361 0.000
M84.0 Malunion of fracture
0.639 0.361 0.000
S51.9 Open wound of forearm, part unspecified
0.637 0.363 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.636 0.364 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.636 0.364 0.000
E29 Testicular dysfunction
0.635 0.364 0.000
H60 Otitis externa
0.636 0.364 0.000
A41 Other septicaemia
0.635 0.365 0.000
O14.0 Moderate preeclampsia
0.635 0.365 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.635 0.365 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.634 0.366 0.000
R46 Symptoms and signs involving appearance and behaviour
0.634 0.366 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.633 0.367 0.000
M81.20 Osteoporosis of disuse (Multiple sites)
0.632 0.368 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.632 0.368 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.632 0.368 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.632 0.368 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.632 0.368 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.632 0.368 0.000
T36 Poisoning by systemic antibiotics
0.632 0.368 0.000
S05 Injury of eye and orbit
0.632 0.368 0.000
O20.0 Threatened abortion
0.632 0.368 0.000
W22.9 Unspecified place
0.631 0.369 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.631 0.369 0.000
M67.4 Ganglion
0.630 0.369 0.000
D69 Purpura and other haemorrhagic conditions
0.628 0.372 0.000
S98 Traumatic amputation of ankle and foot
0.627 0.373 0.000
S97 Crushing injury of ankle and foot
0.627 0.373 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.627 0.373 0.000
S95 Injury of blood vessels at ankle and foot level
0.627 0.373 0.000
S94 Injury of nerves at ankle and foot level
0.627 0.373 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.627 0.373 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.626 0.373 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.626 0.374 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.626 0.374 0.000
E07.9 Disorder of thyroid, unspecified
0.625 0.375 0.000
M92 Other juvenile osteochondrosis
0.624 0.376 0.000
O85 Puerperal sepsis
0.622 0.378 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.622 0.378 0.000
S00.9 Superficial injury of head, part unspecified
0.621 0.379 0.000
T23 Burn and corrosion of wrist and hand
0.620 0.380 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.620 0.380 0.000
T17 Foreign body in respiratory tract
0.620 0.380 0.000
M40 Kyphosis and lordosis
0.620 0.380 0.000
E23 Hypofunction and other disorders of pituitary gland
0.619 0.381 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.619 0.381 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.618 0.382 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.618 0.382 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.618 0.382 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.618 0.382 0.000
W29 Contact with other powered hand tools and household machinery
0.617 0.383 0.000
Q89 Other congenital malformations, not elsewhere classified
0.616 0.383 0.000
O15 Eclampsia
0.616 0.384 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.616 0.384 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.616 0.384 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.616 0.384 0.000
Y84.8 Other medical procedures
0.616 0.384 0.000
R41.2 Retrograde amnesia
0.615 0.385 0.000
W21.9 Unspecified place
0.615 0.385 0.000
B00 Herpesviral [herpes simplex] infections
0.614 0.386 0.000
E27.8 Other specified disorders of adrenal gland
0.613 0.387 0.000
H90.5 Sensorineural hearing loss, unspecified
0.613 0.387 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.613 0.387 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.613 0.387 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.612 0.388 0.000
M88 Paget's disease of bone [osteitis deformans]
0.612 0.388 0.000
Q00-Q07 Congenital malformations of the nervous system
0.612 0.388 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.612 0.388 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.612 0.388 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.612 0.388 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.612 0.388 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.612 0.388 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.612 0.388 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.612 0.388 0.000
E10-E14 Diabetes mellitus
0.611 0.389 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.610 0.390 0.000
E46 Unspecified protein-energy malnutrition
0.610 0.390 0.000
S01.1 Open wound of eyelid and periocular area
0.609 0.391 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.609 0.391 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.609 0.391 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.609 0.391 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.609 0.391 0.000
M07 Psoriatic and enteropathic arthropathies
0.608 0.391 0.000
R74.8 Abnormal levels of other serum enzymes
0.608 0.392 0.000
S06.2 Diffuse brain injury
0.608 0.392 0.000
T75 Effects of other external causes
0.607 0.392 0.000
B99-B99 Other infectious diseases
0.607 0.393 0.000
T19 Foreign body in genito-urinary tract
0.606 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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