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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34835292
log Bayes Factor = 6.28298
Chromosome 21   position 17,333,558  (GRCh37) Explore rs34835292 on Ensembl!
Variant rs34835292 is part of Cluster X0125

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.996 0.004 0.000
Chapter II Neoplasms
0.993 0.007 0.000
C15-C26 Malignant neoplasms of digestive organs
0.993 0.007 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.007 0.993
C15 Malignant neoplasm of oesophagus
0.991 0.009 0.000
D00-D09 In situ neoplasms
0.972 0.028 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.968 0.032 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.968 0.032 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.945 0.055 0.000
C15.9 Oesophagus, unspecified
0.941 0.059 0.000
C15.5 Lower third of oesophagus
0.938 0.062 0.000
C21 Malignant neoplasm of anus and anal canal
0.938 0.062 0.000
C18 Malignant neoplasm of colon
0.935 0.065 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.928 0.072 0.000
C18.9 Colon, unspecified
0.920 0.080 0.000
C85.1 B-cell lymphoma, unspecified
0.918 0.082 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.914 0.086 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.904 0.096 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.899 0.101 0.000
C15.4 Middle third of oesophagus
0.896 0.104 0.000
C81 Hodgkin's disease
0.894 0.106 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.109 0.891
D05 Carcinoma in situ of breast
0.884 0.116 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.877 0.123 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.123 0.877
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.130 0.870
D05.1 Intraductal carcinoma in situ
0.859 0.141 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.855 0.145 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.840 0.160 0.000
C15.3 Upper third of oesophagus
0.830 0.170 0.000
C50-C50 Malignant neoplasm of breast
0.828 0.172 0.000
C18.1 Appendix
0.827 0.173 0.000
C21.1 Anal canal
0.823 0.177 0.000
C22.9 Liver, unspecified
0.819 0.181 0.000
D03 Melanoma in situ
0.817 0.183 0.000
C81.9 Hodgkin's disease, unspecified
0.812 0.188 0.000
C95 Leukaemia of unspecified cell type
0.807 0.193 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.193 0.807
C91 Lymphoid leukaemia
0.805 0.195 0.000
C21.0 Anus, unspecified
0.805 0.195 0.000
C83.0 Small cell (diffuse)
0.799 0.201 0.000
C83.3 Large cell (diffuse)
0.798 0.202 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.797 0.203 0.000
C82.2 Large cell, follicular
0.795 0.205 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.792 0.208 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.789 0.211 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.789 0.211 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.786 0.214 0.000
C10 Malignant neoplasm of oropharynx
0.786 0.214 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.786 0.214 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.216 0.784
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.784 0.216 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.782 0.218 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.231 0.769
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.760 0.240 0.000
C18.0 Caecum
0.755 0.245 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.755 0.245 0.000
C83.7 Burkitt's tumour
0.754 0.246 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.750 0.249 0.000
D07.2 Vagina
0.749 0.251 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.748 0.252 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.746 0.254 0.000
D07.1 Vulva
0.739 0.261 0.000
C84.4 Peripheral T-cell lymphoma
0.737 0.263 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.727 0.273 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.726 0.273 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.725 0.275 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.723 0.277 0.000
D03.5 Melanoma in situ of trunk
0.722 0.278 0.000
C92 Myeloid leukaemia
0.722 0.278 0.000
C82.0 Small cleaved cell, follicular
0.717 0.283 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.716
C18.4 Transverse colon
0.716 0.283 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.715 0.285 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.714 0.285 0.000
C94 Other leukaemias of specified cell type
0.714 0.285 0.000
C93 Monocytic leukaemia
0.714 0.285 0.000
C86 Other specified types of T/NK-cell lymphoma
0.714 0.285 0.000
C15.8 Overlapping lesion of oesophagus
0.710 0.290 0.000
C15.2 Abdominal part of oesophagus
0.710 0.290 0.000
C15.1 Thoracic part of oesophagus
0.710 0.290 0.000
C15.0 Cervical part of oesophagus
0.710 0.290 0.000
C50 Malignant neoplasm of breast
0.709 0.291 0.000
D37.0 Lip, oral cavity and pharynx
0.708 0.292 0.000
D37.7 Other digestive organs
0.707 0.293 0.000
C10.9 Oropharynx, unspecified
0.705 0.295 0.000
C12 Malignant neoplasm of pyriform sinus
0.704 0.295 0.000
C90.2 Plasmacytoma, extramedullary
0.701 0.299 0.000
C88 Malignant immunoproliferative diseases
0.701 0.299 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.701 0.299 0.000
C82.6 Cutaneous follicle centre lymphoma
0.694 0.306 0.000
C82.5 Diffuse follicle centre lymphoma
0.694 0.306 0.000
C82.4 Follicular lymphoma grade IIIb
0.694 0.306 0.000
C82.3 Follicular lymphoma grade IIIa
0.694 0.306 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.694 0.306 0.000
C85.0 Lymphosarcoma
0.694 0.306 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.691 0.309 0.000
D47.2 Monoclonal gammopathy
0.691 0.309 0.000
C16 Malignant neoplasm of stomach
0.688 0.312 0.000
C22.1 Intrahepatic bile duct carcinoma
0.686 0.314 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.315 0.685
D37.9 Digestive organ, unspecified
0.684 0.316 0.000
D09 Carcinoma in situ of other and unspecified sites
0.684 0.316 0.000
D05.0 Lobular carcinoma in situ
0.684 0.316 0.000
D37.5 Rectum
0.682 0.318 0.000
C18.3 Hepatic flexure
0.681 0.318 0.000
C22.0 Liver cell carcinoma
0.678 0.322 0.000
D43.2 Brain, unspecified
0.673 0.327 0.000
C21.2 Cloacogenic zone
0.672 0.328 0.000
C95.9 Leukaemia, unspecified
0.671 0.328 0.000
C18.8 Overlapping lesion of colon
0.670 0.329 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.669 0.331 0.000
C91.5 Adult T-cell leukaemia
0.668 0.332 0.000
C05 Malignant neoplasm of palate
0.666 0.334 0.000
C83.6 Undifferentiated (diffuse)
0.665 0.334 0.000
C83.5 Lymphoblastic (diffuse)
0.665 0.334 0.000
C83.4 Immunoblastic (diffuse)
0.665 0.334 0.000
C83.2 Mixed small and large cell (diffuse)
0.665 0.334 0.000
C81.1 Nodular sclerosis
0.665 0.335 0.000
C23 Malignant neoplasm of gallbladder
0.659 0.341 0.000
C11 Malignant neoplasm of nasopharynx
0.659 0.341 0.000
D37.2 Small intestine
0.659 0.341 0.000
D00.0 Lip, oral cavity and pharynx
0.657 0.343 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.655 0.345 0.000
C22.7 Other specified carcinomas of liver
0.648 0.352 0.000
C22.4 Other sarcomas of liver
0.648 0.352 0.000
C22.3 Angiosarcoma of liver
0.648 0.352 0.000
C22.2 Hepatoblastoma
0.648 0.352 0.000
C84.5 Other and unspecified T-cell lymphomas
0.647 0.353 0.000
D07.5 Prostate
0.646 0.354 0.000
D44.0 Thyroid gland
0.645 0.355 0.000
C13 Malignant neoplasm of hypopharynx
0.644 0.355 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.644 0.355 0.000
C04 Malignant neoplasm of floor of mouth
0.644 0.355 0.000
C03 Malignant neoplasm of gum
0.644 0.355 0.000
C00 Malignant neoplasm of lip
0.644 0.355 0.000
C81.7 Other Hodgkin's disease
0.641 0.359 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.641 0.359 0.000
C81.3 Lymphocytic depletion
0.641 0.359 0.000
C81.2 Mixed cellularity
0.641 0.359 0.000
C81.0 Lymphocytic predominance
0.641 0.359 0.000
C50.2 Upper-inner quadrant of breast
0.640 0.360 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.639 0.361 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.638 0.362 0.000
D03.4 Melanoma in situ of scalp and neck
0.635 0.364 0.000
C83.1 Small cleaved cell (diffuse)
0.635 0.365 0.000
D05.7 Other carcinoma in situ of breast
0.634 0.366 0.000
C50.8 Overlapping lesion of breast
0.634 0.366 0.000
C06.0 Cheek mucosa
0.634 0.366 0.000
C09 Malignant neoplasm of tonsil
0.633 0.367 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.629 0.370 0.000
D07.6 Other and unspecified male genital organs
0.629 0.371 0.000
D07.3 Other and unspecified female genital organs
0.629 0.371 0.000
D07.0 Endometrium
0.629 0.371 0.000
C06.9 Mouth, unspecified
0.627 0.372 0.000
C50.5 Lower-outer quadrant of breast
0.627 0.373 0.000
D47.1 Chronic myeloproliferative disease
0.625 0.375 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.622 0.378 0.000
D07.4 Penis
0.622 0.378 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.616 0.383 0.000
D44.4 Craniopharyngeal duct
0.616 0.384 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.613 0.387 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.613 0.387 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.613 0.387 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.613 0.387 0.000
C84.3 Lymphoepithelioid lymphoma
0.613 0.387 0.000
C84.2 T-zone lymphoma
0.613 0.387 0.000
C84.1 Sezary's diease
0.613 0.387 0.000
C84.0 Mycosis fungoides
0.613 0.387 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.612 0.388 0.000
D44.8 Pluriglandular involvement
0.608 0.392 0.000
D06 Carcinoma in situ of cervix uteri
0.607 0.393 0.000
D04 Carcinoma in situ of skin
0.607 0.393 0.000
C91.0 Acute lymphoblastic leukaemia
0.605 0.395 0.000
C06.2 Retromolar area
0.604 0.396 0.000
D37.3 Appendix
0.602 0.397 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.602 0.398 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.601 0.399 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.598 0.402 0.000
C50.0 Nipple and areola
0.597 0.403 0.000
C25 Malignant neoplasm of pancreas
0.596 0.404 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.596 0.404 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.595 0.404 0.000
D01.3 Anus and anal canal
0.592 0.408 0.000
D38.1 Trachea, bronchus and lung
0.586 0.414 0.000
D03.9 Melanoma in situ, unspecified
0.585 0.414 0.000
D03.8 Melanoma in situ of other sites
0.585 0.414 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.585 0.414 0.000
D03.0 Melanoma in situ of lip
0.585 0.414 0.000
D37.1 Stomach
0.581 0.419 0.000
C24.9 Biliary tract, unspecified
0.581 0.419 0.000
C91.4 Hairy-cell leukaemia
0.579 0.421 0.000
C95.7 Other leukaemia of unspecified cell type
0.579 0.421 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.579 0.421 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.579 0.421 0.000
C95.0 Acute leukaemia of unspecified cell type
0.579 0.421 0.000
C91.9 Lymphoid leukaemia, unspecified
0.577 0.423 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.577 0.423 0.000
C91.7 Other lymphoid leukaemia
0.577 0.423 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.577 0.423 0.000
C91.3 Prolymphocytic leukaemia
0.577 0.423 0.000
C91.2 Subacute lymphocytic leukaemia
0.577 0.423 0.000
C69 Malignant neoplasm of eye and adnexa
0.577 0.423 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.574 0.426 0.000
C07 Malignant neoplasm of parotid gland
0.572 0.428 0.000
C26.0 Intestinal tract, part unspecified
0.572 0.428 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.571 0.429 0.000
M06 Other rheumatoid arthritis
0.000 0.430 0.570
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.567 0.432 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.567 0.432 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.567 0.432 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.567 0.432 0.000
D00.2 Stomach
0.565 0.434 0.000
D00.1 Oesophagus
0.565 0.434 0.000
D44.9 Endocrine gland, unspecified
0.565 0.434 0.000
D44.7 Aortic body and other paraganglia
0.565 0.434 0.000
D44.6 Carotid body
0.565 0.434 0.000
D44.5 Pineal gland
0.565 0.434 0.000
D44.3 Pituitary gland
0.565 0.434 0.000
D44.2 Parathyroid gland
0.565 0.434 0.000
D44.1 Adrenal gland
0.565 0.434 0.000
C24.1 Ampulla of Vater
0.565 0.435 0.000
C92.0 Acute myeloid leukaemia
0.564 0.436 0.000
C10.8 Overlapping lesion of oropharynx
0.563 0.437 0.000
C10.4 Branchial cleft
0.563 0.437 0.000
C10.3 Posterior wall of oropharynx
0.563 0.437 0.000
C10.2 Lateral wall of oropharynx
0.563 0.437 0.000
C10.1 Anterior surface of epiglottis
0.563 0.437 0.000
C10.0 Vallecula
0.563 0.437 0.000
C90.3 Solitary plasmacytoma
0.563 0.437 0.000
C90.1 Plasma cell leukaemia
0.563 0.437 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.561 0.439 0.000
C06.1 Vestibule of mouth
0.561 0.439 0.000
C92.4 Acute promyelocytic leukaemia
0.560 0.440 0.000
D45 Polycythaemia vera
0.556 0.444 0.000
C01 Malignant neoplasm of base of tongue
0.551 0.449 0.000
D02.0 Larynx
0.547 0.452 0.000
D43.9 Central nervous system, unspecified
0.545 0.455 0.000
D43.7 Other parts of central nervous system
0.545 0.455 0.000
D43.4 Spinal cord
0.545 0.455 0.000
D43.3 Cranial nerves
0.545 0.455 0.000
D43.1 Brain, infratentorial
0.545 0.455 0.000
C91.1 Chronic lymphocytic leukaemia
0.544 0.456 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.543 0.457 0.000
D01.9 Digestive organ, unspecified
0.538 0.462 0.000
D01.7 Other specified digestive organs
0.538 0.462 0.000
D01.5 Liver, gallbladder and bile ducts
0.538 0.462 0.000
D01.4 Other and unspecified parts of intestine
0.538 0.462 0.000
D01.2 Rectum
0.538 0.462 0.000
D01.1 Rectosigmoid junction
0.538 0.462 0.000
D01.0 Colon
0.538 0.462 0.000
D37.6 Liver, gallbladder and bile ducts
0.538 0.462 0.000
C37 Malignant neoplasm of thymus
0.537 0.463 0.000
C26.9 Ill-defined sites within the digestive system
0.536 0.464 0.000
C26.8 Overlapping lesion of digestive system
0.536 0.464 0.000
C26.1 Spleen
0.536 0.464 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.535 0.465 0.000
D04.4 Skin of scalp and neck
0.535 0.465 0.000
C24.8 Overlapping lesion of biliary tract
0.535 0.465 0.000
C50.3 Lower-inner quadrant of breast
0.530 0.470 0.000
C16.0 Cardia
0.528 0.472 0.000
C16.2 Body of stomach
0.526 0.474 0.000
D46 Myelodysplastic syndromes
0.524 0.475 0.000
C18.5 Splenic flexure
0.523 0.476 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.521 0.479 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.521 0.479 0.000
C17 Malignant neoplasm of small intestine
0.520 0.479 0.000
C51-C58 Malignant neoplasms of female genital organs
0.521 0.479 0.000
D02.4 Respiratory system, unspecified
0.520 0.480 0.000
D02.3 Other parts of respiratory system
0.520 0.480 0.000
D02.2 Bronchus and lung
0.520 0.480 0.000
D02.1 Trachea
0.520 0.480 0.000
D38.6 Respiratory organ, unspecified
0.518 0.482 0.000
D38.5 Other respiratory organs
0.518 0.482 0.000
D38.4 Thymus
0.518 0.482 0.000
D38.3 Mediastinum
0.518 0.482 0.000
D38.2 Pleura
0.518 0.482 0.000
D38.0 Larynx
0.518 0.482 0.000
C92.9 Myeloid leukaemia, unspecified
0.518 0.482 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.518 0.482 0.000
C92.7 Other myeloid leukaemia
0.518 0.482 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.518 0.482 0.000
C92.5 Acute myelomonocytic leukaemia
0.518 0.482 0.000
C92.3 Myeloid sarcoma
0.518 0.482 0.000
C92.2 Subacute myeloid leukaemia
0.518 0.482 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.513 0.487 0.000
C31 Malignant neoplasm of accessory sinuses
0.513 0.487 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.513 0.487 0.000
C33 Malignant neoplasm of trachea
0.513 0.487 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.512 0.488 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.512 0.488 0.000
C86.4 Blastic NK-cell lymphoma
0.512 0.488 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.512 0.488 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.512 0.488 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.512 0.488 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.512 0.488 0.000
C93.9 Monocytic leukaemia, unspecified
0.512 0.488 0.000
C93.7 Other monocytic leukaemia
0.512 0.488 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.512 0.488 0.000
C93.2 Subacute monocytic leukaemia
0.512 0.488 0.000
C93.1 Chronic monocytic leukaemia
0.512 0.488 0.000
C93.0 Acute monocytic leukaemia
0.512 0.488 0.000
C94.7 Other specified leukaemias
0.512 0.488 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.512 0.488 0.000
C94.5 Acute myelofibrosis
0.512 0.488 0.000
C94.4 Acute panmyelosis
0.512 0.488 0.000
C94.3 Mast cell leukaemia
0.512 0.488 0.000
C94.2 Acute megakaryoblastic leukaemia
0.512 0.488 0.000
C94.1 Chronic erythraemia
0.512 0.488 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.512 0.488 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.512 0.488 0.000
C96.8 Histiocytic sarcoma
0.512 0.488 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.512 0.488 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.512 0.488 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.512 0.488 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.512 0.488 0.000
C96.3 True histiocytic lymphoma
0.512 0.488 0.000
C96.2 Malignant mast cell tumour
0.512 0.488 0.000
C96.1 Malignant histiocytosis
0.512 0.488 0.000
C96.0 Letterer-Siwe disease
0.512 0.488 0.000
C14.0 Pharynx, unspecified
0.504 0.496 0.000
C32 Malignant neoplasm of larynx
0.504 0.496 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.502 0.497 0.000
C88.7 Other malignant immunoproliferative diseases
0.502 0.497 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.502 0.497 0.000
C88.3 Immunoproliferative small intestinal disease
0.502 0.497 0.000
C88.2 Gamma heavy chain disease
0.502 0.497 0.000
C88.1 Alpha heavy chain disease
0.502 0.497 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.502 0.498 0.000
C70 Malignant neoplasm of meninges
0.502 0.498 0.000
C05.1 Soft palate
0.499 0.501 0.000
C18.6 Descending colon
0.498 0.502 0.000
D39.0 Uterus
0.497 0.503 0.000
D04.2 Skin of ear and external auricular canal
0.496 0.504 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.496 0.504 0.000
C74 Malignant neoplasm of adrenal gland
0.496 0.504 0.000
C60-C63 Malignant neoplasms of male genital organs
0.495 0.505 0.000
D47.4 Osteomyelofibrosis
0.494 0.506 0.000
C16.8 Overlapping lesion of stomach
0.493 0.507 0.000
C16.6 Greater curvature of stomach, unspecified
0.493 0.507 0.000
C16.5 Lesser curvature of stomach, unspecified
0.493 0.507 0.000
C16.4 Pylorus
0.493 0.507 0.000
C16.3 Pyloric antrum
0.493 0.507 0.000
C16.1 Fundus of stomach
0.493 0.507 0.000
D09.9 Carcinoma in situ, unspecified
0.490 0.510 0.000
D09.7 Carcinoma in situ of other specified sites
0.490 0.510 0.000
D09.3 Thyroid and other endocrine glands
0.490 0.510 0.000
D09.2 Eye
0.490 0.510 0.000
D09.1 Other and unspecified urinary organs
0.490 0.510 0.000
C25.2 Tail of pancreas
0.490 0.510 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.489 0.511 0.000
C50.6 Axillary tail of breast
0.488 0.512 0.000
C11.9 Nasopharynx, unspecified
0.487 0.513 0.000
D06.0 Endocervix
0.487 0.513 0.000
D43.0 Brain, supratentorial
0.484 0.516 0.000
C24.0 Extrahepatic bile duct
0.481 0.519 0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.480 0.520 0.000
C14.2 Waldeyer's ring
0.480 0.520 0.000
C69.3 Choroid
0.478 0.522 0.000
C05.9 Palate, unspecified
0.477 0.522 0.000
C05.8 Overlapping lesion of palate
0.477 0.522 0.000
C05.2 Uvula
0.477 0.522 0.000
C05.0 Hard palate
0.477 0.522 0.000
D09.0 Bladder
0.477 0.523 0.000
C73 Malignant neoplasm of thyroid gland
0.474 0.525 0.000
D37.4 Colon
0.473 0.527 0.000
C11.8 Overlapping lesion of nasopharynx
0.472 0.527 0.000
C11.3 Anterior wall of nasopharynx
0.472 0.527 0.000
C11.2 Lateral wall of nasopharynx
0.472 0.527 0.000
C11.1 Posterior wall of nasopharynx
0.472 0.527 0.000
C11.0 Superior wall of nasopharynx
0.472 0.527 0.000
D42.9 Meninges, unspecified
0.470 0.530 0.000
D42.1 Spinal meninges
0.470 0.530 0.000
D42.0 Cerebral meninges
0.470 0.530 0.000
D40.0 Prostate
0.470 0.530 0.000
C38.4 Pleura
0.467 0.533 0.000
C51 Malignant neoplasm of vulva
0.466 0.534 0.000
C00.9 Lip, unspecified
0.462 0.538 0.000
C00.8 Overlapping lesion of lip
0.462 0.538 0.000
C00.6 Commissure of lip
0.462 0.538 0.000
C00.5 Lip, unspecified, inner aspect
0.462 0.538 0.000
C00.4 Lower lip, inner aspect
0.462 0.538 0.000
C00.3 Upper lip, inner aspect
0.462 0.538 0.000
C00.2 External lip, unspecified
0.462 0.538 0.000
C00.1 External lower lip
0.462 0.538 0.000
C00.0 External upper lip
0.462 0.538 0.000
C03.9 Gum, unspecified
0.462 0.538 0.000
C03.1 Lower gum
0.462 0.538 0.000
C03.0 Upper gum
0.462 0.538 0.000
C04.9 Floor of mouth, unspecified
0.462 0.538 0.000
C04.8 Overlapping lesion of floor of mouth
0.462 0.538 0.000
C04.1 Lateral floor of mouth
0.462 0.538 0.000
C04.0 Anterior floor of mouth
0.462 0.538 0.000
C08.9 Major salivary gland, unspecified
0.462 0.538 0.000
C08.8 Overlapping lesion of major salivary glands
0.462 0.538 0.000
C08.1 Sublingual gland
0.462 0.538 0.000
C08.0 Submandibular gland
0.462 0.538 0.000
C13.9 Hypopharynx, unspecified
0.462 0.538 0.000
C13.8 Overlapping lesion of hypopharynx
0.462 0.538 0.000
C13.2 Posterior wall of hypopharynx
0.462 0.538 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.462 0.538 0.000
C13.0 Postcricoid region
0.462 0.538 0.000
D40.9 Male genital organ, unspecified
0.458 0.542 0.000
D40.7 Other male genital organs
0.458 0.542 0.000
C09.8 Overlapping lesion of tonsil
0.454 0.546 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.454 0.546 0.000
C09.0 Tonsillar fossa
0.454 0.546 0.000
C09.9 Tonsil, unspecified
0.443 0.557 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.440 0.560 0.000
D39.9 Female genital organ, unspecified
0.439 0.561 0.000
D39.7 Other female genital organs
0.439 0.561 0.000
D39.2 Placenta
0.439 0.561 0.000
D06.7 Other parts of cervix
0.435 0.565 0.000
D06.1 Exocervix
0.435 0.565 0.000
D04.9 Skin, unspecified
0.435 0.565 0.000
D04.8 Skin of other sites
0.435 0.565 0.000
D04.1 Skin of eyelid, including canthus
0.435 0.565 0.000
D04.0 Skin of lip
0.435 0.565 0.000
C43 Malignant melanoma of skin
0.433 0.567 0.000
D41.9 Urinary organ, unspecified
0.431 0.569 0.000
D41.7 Other urinary organs
0.431 0.569 0.000
D41.3 Urethra
0.431 0.569 0.000
D41.2 Ureter
0.431 0.569 0.000
D41.1 Renal pelvis
0.431 0.569 0.000
C69.9 Eye, unspecified
0.430 0.570 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.570 0.430
D40.1 Testis
0.428 0.571 0.000
C25.8 Overlapping lesion of pancreas
0.428 0.572 0.000
C25.7 Other parts of pancreas
0.428 0.572 0.000
C25.4 Endocrine pancreas
0.428 0.572 0.000
C25.3 Pancreatic duct
0.428 0.572 0.000
C02.8 Overlapping lesion of tongue
0.427 0.573 0.000
C02.4 Lingual tonsil
0.427 0.573 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.427 0.573 0.000
C02.2 Ventral surface of tongue
0.427 0.573 0.000
C02.0 Dorsal surface of tongue
0.427 0.573 0.000
C51.9 Vulva, unspecified
0.427 0.573 0.000
D41.4 Bladder
0.415 0.585 0.000
C69.8 Overlapping lesion of eye and adnexa
0.414 0.586 0.000
C69.6 Orbit
0.414 0.586 0.000
C69.5 Lachrymal gland and duct
0.414 0.586 0.000
C69.4 Ciliary body
0.414 0.586 0.000
C69.2 Retina
0.414 0.586 0.000
C69.1 Cornea
0.414 0.586 0.000
C69.0 Conjunctiva
0.414 0.586 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.412 0.588 0.000
C34 Malignant neoplasm of bronchus and lung
0.411 0.588 0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.409 0.591 0.000
C38.3 Mediastinum, part unspecified
0.409 0.591 0.000
C38.2 Posterior mediastinum
0.409 0.591 0.000
C38.1 Anterior mediastinum
0.409 0.591 0.000
C38.0 Heart
0.409 0.591 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.591 0.409
M06.2 Rheumatoid bursitis
0.000 0.591 0.409
M06.1 Adult-onset Still's disease
0.000 0.591 0.409
C25.9 Pancreas, unspecified
0.408 0.592 0.000
C02.9 Tongue, unspecified
0.407 0.593 0.000
M06.3 Rheumatoid nodule
0.000 0.596 0.404
C02.1 Border of tongue
0.402 0.598 0.000
C92.1 Chronic myeloid leukaemia
0.400 0.599 0.000
C41.1 Mandible
0.398 0.602 0.000
D41.0 Kidney
0.397 0.603 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.389 0.611 0.000
D04.7 Skin of lower limb, including hip
0.389 0.611 0.000
C90.0 Multiple myeloma
0.388 0.612 0.000
C25.1 Body of pancreas
0.384 0.616 0.000
C41.9 Bone and articular cartilage, unspecified
0.384 0.616 0.000
C41.8 Overlapping lesion of bone and articular cartilage
0.384 0.616 0.000
C41.4 Pelvic bones, sacrum and coccyx
0.384 0.616 0.000
C41.3 Ribs, sternum and clavicle
0.384 0.616 0.000
C41.2 Vertebral column
0.384 0.616 0.000
C41.0 Bones of skull and face
0.384 0.616 0.000
C32.0 Glottis
0.382 0.618 0.000
D46.7 Other myelodysplastic syndromes
0.376 0.624 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.376 0.624 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.376 0.624 0.000
D46.4 Refractory anaemia, unspecified
0.376 0.624 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.376 0.624 0.000
D46.2 Refractory anaemia with excess of blasts
0.376 0.624 0.000
D46.1 Refractory anaemia with sideroblasts
0.376 0.624 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.376 0.624 0.000
C18.2 Ascending colon
0.374 0.626 0.000
C40.9 Bone and articular cartilage of limb, unspecified
0.373 0.626 0.000
C40.8 Overlapping lesion of bone and articular cartilage of limbs
0.373 0.626 0.000
C40.3 Short bones of lower limb
0.373 0.626 0.000
C40.2 Long bones of lower limb
0.373 0.626 0.000
C40.1 Short bones of upper limb
0.373 0.626 0.000
C40.0 Scapula and long bones of upper limb
0.373 0.626 0.000
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)
0.373 0.626 0.000
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)
0.373 0.626 0.000
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)
0.373 0.626 0.000
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)
0.373 0.626 0.000
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)
0.373 0.626 0.000
C17.8 Overlapping lesion of small intestine
0.373 0.626 0.000
C17.3 Meckel's diverticulum
0.373 0.626 0.000
C17.1 Jejunum
0.373 0.626 0.000
C58 Malignant neoplasm of placenta
0.373 0.627 0.000
D04.5 Skin of trunk
0.373 0.627 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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