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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34979634
log Bayes Factor = 10.2881
Chromosome 7   position 18,181,230  (GRCh37) Explore rs34979634 on Ensembl!
Variant rs34979634 is part of Cluster X0079

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
H90-H95 Other disorders of ear
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
H90 Conductive and sensorineural hearing loss
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
M05-M14 Inflammatory polyarthropathies
0.990 0.010 0.000
Chapter II Neoplasms
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.981 0.019 0.000
H91 Other hearing loss
0.981 0.019 0.000
A30-A49 Other bacterial diseases
0.981 0.019 0.000
H65-H75 Diseases of middle ear and mastoid
0.981 0.019 0.000
A00-A09 Intestinal infectious diseases
0.979 0.021 0.000
Chapter V Mental and behavioural disorders
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.977 0.023 0.000
M13 Other arthritis
0.973 0.027 0.000
H90.5 Sensorineural hearing loss, unspecified
0.971 0.029 0.000
A04 Other bacterial intestinal infections
0.970 0.030 0.000
H92 Otalgia and effusion of ear
0.969 0.031 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.968 0.032 0.000
F30-F39 Mood [affective] disorders
0.968 0.032 0.000
H91.9 Hearing loss, unspecified
0.961 0.039 0.000
M13.9 Arthritis, unspecified
0.960 0.040 0.000
H92.0 Otalgia
0.954 0.046 0.000
M45-M49 Spondylopathies
0.953 0.047 0.000
F31 Bipolar affective disorder
0.949 0.051 0.000
E00-E07 Disorders of thyroid gland
0.948 0.052 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.943 0.057 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.938 0.062 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.936 0.064 0.000
A04.8 Other specified bacterial intestinal infections
0.932 0.068 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.930 0.070 0.000
F31.9 Bipolar affective disorder, unspecified
0.923 0.077 0.000
E20-E35 Disorders of other endocrine glands
0.923 0.077 0.000
M65-M68 Disorders of synovium and tendon
0.918 0.082 0.000
A41 Other septicaemia
0.918 0.082 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.916 0.084 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.913 0.087 0.000
H90.2 Conductive hearing loss, unspecified
0.911 0.089 0.000
L20-L30 Dermatitis and eczema
0.909 0.091 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.907 0.093 0.000
H71 Cholesteatoma of middle ear
0.907 0.093 0.000
Chapter XXII Codes for special purposes
0.904 0.096 0.000
M48 Other spondylopathies
0.902 0.098 0.000
M46 Other inflammatory spondylopathies
0.897 0.103 0.000
F33 Recurrent depressive disorder
0.897 0.103 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.896 0.104 0.000
E10-E14 Diabetes mellitus
0.896 0.104 0.000
M05 Seropositive rheumatoid arthritis
0.895 0.105 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.895 0.105 0.000
C64-C68 Malignant neoplasms of urinary tract
0.895 0.105 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.888 0.112 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.888 0.112 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.885 0.115 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.885 0.115 0.000
C83.3 Large cell (diffuse)
0.884 0.116 0.000
M20-M25 Other joint disorders
0.883 0.117 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.883 0.117 0.000
H72 Perforation of tympanic membrane
0.878 0.122 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.875 0.125 0.000
L91 Hypertrophic disorders of skin
0.873 0.127 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.870 0.130 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.869 0.131 0.000
E10 Insulin-dependent diabetes mellitus
0.868 0.132 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.862 0.138 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.859 0.141 0.000
E06 Thyroiditis
0.854 0.146 0.000
W20-W49 Exposure to inanimate mechanical forces
0.852 0.148 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.850 0.150 0.000
E10.9 Without complications
0.850 0.150 0.000
A41.9 Septicaemia, unspecified
0.849 0.151 0.000
M48.0 Spinal stenosis
0.846 0.154 0.000
F60-F69 Disorders of adult personality and behaviour
0.846 0.154 0.000
A49 Bacterial infection of unspecified site
0.845 0.155 0.000
E27 Other disorders of adrenal gland
0.844 0.156 0.000
F33.9 Recurrent depressive disorder, unspecified
0.841 0.159 0.000
L91.8 Other hypertrophic disorders of skin
0.841 0.159 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.841 0.159 0.000
G70-G73 Diseases of myoneural junction and muscle
0.840 0.160 0.000
E04 Other non-toxic goitre
0.839 0.161 0.000
E40-E46 Malnutrition
0.839 0.161 0.000
C71 Malignant neoplasm of brain
0.836 0.164 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.835 0.165 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.834 0.166 0.000
L27 Dermatitis due to substances taken internally
0.833 0.167 0.000
M80-M85 Disorders of bone density and structure
0.831 0.169 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.830 0.170 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.827 0.173 0.000
M48.02 Spinal stenosis (Cervical region)
0.827 0.173 0.000
M86-M90 Other osteopathies
0.825 0.175 0.000
C50-C50 Malignant neoplasm of breast
0.824 0.176 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.824 0.176 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.822 0.178 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.821 0.179 0.000
M20 Acquired deformities of fingers and toes
0.821 0.179 0.000
H74 Other disorders of middle ear and mastoid
0.821 0.179 0.000
H69 Other disorders of Eustachian tube
0.821 0.179 0.000
G57 Mononeuropathies of lower limb
0.821 0.179 0.000
C73 Malignant neoplasm of thyroid gland
0.817 0.183 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.816 0.184 0.000
M65 Synovitis and tenosynovitis
0.813 0.187 0.000
A40 Streptococcal septicaemia
0.813 0.187 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.806 0.194 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.806 0.194 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.804 0.196 0.000
Y95 Nosocomial condition
0.803 0.197 0.000
M66 Spontaneous rupture of synovium and tendon
0.799 0.201 0.000
C90.0 Multiple myeloma
0.799 0.201 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.798 0.202 0.000
E23 Hypofunction and other disorders of pituitary gland
0.797 0.203 0.000
M20.5 Other deformities of toe(s) (acquired)
0.796 0.204 0.000
Y52 Agents primarily affecting the cardiovascular system
0.794 0.206 0.000
H91.1 Presbycusis
0.793 0.207 0.000
G54 Nerve root and plexus disorders
0.792 0.208 0.000
W50-W64 Exposure to animate mechanical forces
0.790 0.210 0.000
H72.0 Central perforation of tympanic membrane
0.788 0.212 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.786 0.214 0.000
C91 Lymphoid leukaemia
0.785 0.215 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.785 0.215 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.785 0.215 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.783 0.217 0.000
F30 Manic episode
0.781 0.219 0.000
A04.5 Campylobacter enteritis
0.781 0.219 0.000
M20.2 Hallux rigidus
0.780 0.220 0.000
A39 Meningococcal infection
0.777 0.223 0.000
E06.3 Autoimmune thyroiditis
0.776 0.224 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.774 0.226 0.000
E05.9 Thyrotoxicosis, unspecified
0.774 0.226 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.773 0.227 0.000
M40-M43 Deforming dorsopathies
0.772 0.228 0.000
L28 Lichen simplex chronicus and prurigo
0.771 0.229 0.000
V98-V99 Other and unspecified transport accidents
0.771 0.229 0.000
C71.1 Frontal lobe
0.770 0.230 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.769 0.231 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.766 0.234 0.000
M11 Other crystal arthropathies
0.765 0.235 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.764 0.236 0.000
A49.9 Bacterial infection, unspecified
0.763 0.237 0.000
G82 Paraplegia and tetraplegia
0.763 0.237 0.000
B99-B99 Other infectious diseases
0.762 0.238 0.000
C88 Malignant immunoproliferative diseases
0.762 0.238 0.000
H70 Mastoiditis and related conditions
0.762 0.238 0.000
C85.1 B-cell lymphoma, unspecified
0.762 0.238 0.000
A46 Erysipelas
0.761 0.239 0.000
V40-V49 Car occupant injured in transport accident
0.759 0.241 0.000
H60-H62 Diseases of external ear
0.753 0.247 0.000
C69 Malignant neoplasm of eye and adnexa
0.752 0.248 0.000
G90-G99 Other disorders of the nervous system
0.751 0.249 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.751 0.249 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.751 0.249 0.000
L91.0 Keloid scar
0.751 0.249 0.000
F60 Specific personality disorders
0.750 0.250 0.000
G71 Primary disorders of muscles
0.748 0.252 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.747 0.253 0.000
Q60-Q64 Congenital malformations of the urinary system
0.747 0.253 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.747 0.253 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.746 0.254 0.000
H90.0 Conductive hearing loss, bilateral
0.745 0.254 0.000
M22 Disorders of patella
0.744 0.256 0.000
G00 Bacterial meningitis, not elsewhere classified
0.744 0.256 0.000
L10-L14 Bullous disorders
0.743 0.257 0.000
A08 Viral and other specified intestinal infections
0.743 0.257 0.000
U80 Agent resistant to penicillin and related antibiotics
0.741 0.259 0.000
L90 Atrophic disorders of skin
0.739 0.261 0.000
G51 Facial nerve disorders
0.738 0.262 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.738 0.262 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.738 0.262 0.000
E10.5 With peripheral circulatory complications
0.736 0.264 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.736 0.264 0.000
F99-F99 Unspecified mental disorder
0.735 0.265 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.735 0.265 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.734 0.266 0.000
G52 Disorders of other cranial nerves
0.733 0.266 0.000
Y40 Systemic antibiotics
0.733 0.267 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.733 0.267 0.000
A02 Other Salmonella infections
0.733 0.267 0.000
E46 Unspecified protein-energy malnutrition
0.732 0.268 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.732 0.268 0.000
L21 Seborrhoeic dermatitis
0.731 0.269 0.000
E24 Cushing's syndrome
0.730 0.269 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.729 0.271 0.000
M14 Arthropathies in other diseases classified elsewhere
0.728 0.272 0.000
C83.0 Small cell (diffuse)
0.728 0.272 0.000
M13.0 Polyarthritis, unspecified
0.728 0.272 0.000
Y43 Primarily systemic agents
0.726 0.274 0.000
M21 Other acquired deformities of limbs
0.724 0.276 0.000
C15-C26 Malignant neoplasms of digestive organs
0.724 0.276 0.000
L08 Other local infections of skin and subcutaneous tissue
0.724 0.276 0.000
A80-A89 Viral infections of the central nervous system
0.723 0.277 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.723 0.277 0.000
E13 Other specified diabetes mellitus
0.722 0.278 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.721 0.279 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.720 0.280 0.000
M20.3 Other deformity of hallux (acquired)
0.718 0.282 0.000
A41.8 Other specified septicaemia
0.718 0.282 0.000
Q80-Q89 Other congenital malformations
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.717 0.283 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.715 0.285 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.715 0.285 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
W44 Foreign body entering into or through eye or natural orifice
0.713 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
M12 Other specific arthropathies
0.710 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.710 0.290 0.000
M08 Juvenile arthritis
0.710 0.290 0.000
L50-L54 Urticaria and erythema
0.709 0.291 0.000
E23.0 Hypopituitarism
0.709 0.291 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.709 0.291 0.000
M89 Other disorders of bone
0.708 0.292 0.000
C50 Malignant neoplasm of breast
0.708 0.292 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.707 0.293 0.000
E04.2 Non-toxic multinodular goitre
0.707 0.293 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.705 0.295 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.704 0.295 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.704 0.296 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.704 0.296 0.000
M80 Osteoporosis with pathological fracture
0.704 0.296 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.703 0.297 0.000
C95 Leukaemia of unspecified cell type
0.703 0.297 0.000
C94 Other leukaemias of specified cell type
0.703 0.297 0.000
C93 Monocytic leukaemia
0.703 0.297 0.000
C86 Other specified types of T/NK-cell lymphoma
0.703 0.297 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.703 0.297 0.000
H91.8 Other specified hearing loss
0.703 0.297 0.000
H91.3 Deaf mutism, not elsewhere classified
0.703 0.297 0.000
H91.2 Sudden idiopathic hearing loss
0.703 0.297 0.000
H91.0 Ototoxic hearing loss
0.703 0.297 0.000
A48 Other bacterial diseases, not elsewhere classified
0.703 0.297 0.000
A44 Bartonellosis
0.703 0.297 0.000
A43 Nocardiosis
0.703 0.297 0.000
A42 Actinomycosis
0.703 0.297 0.000
A37 Whooping cough
0.703 0.297 0.000
A36 Diphtheria
0.703 0.297 0.000
A32 Listeriosis
0.703 0.297 0.000
A31 Infection due to other mycobacteria
0.703 0.297 0.000
A30 Leprosy [Hansen's disease]
0.703 0.297 0.000
A38 Scarlet fever
0.703 0.297 0.000
A35 Other tetanus
0.703 0.297 0.000
A34 Obstetrical tetanus
0.703 0.297 0.000
A33 Tetanus neonatorum
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.703 0.297 0.000
H68 Eustachian salpingitis and obstruction
0.703 0.297 0.000
H67 Otitis media in diseases classified elsewhere
0.703 0.297 0.000
A07 Other protozoal intestinal diseases
0.702 0.298 0.000
A06 Amoebiasis
0.702 0.298 0.000
A05 Other bacterial foodborne intoxications
0.702 0.298 0.000
A03 Shigellosis
0.702 0.298 0.000
A01 Typhoid and paratyphoid fevers
0.702 0.298 0.000
A00 Cholera
0.702 0.298 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.702 0.298 0.000
L05 Pilonidal cyst
0.702 0.298 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.702 0.298 0.000
F70-F79 Mental retardation
0.702 0.298 0.000
E27.9 Disorder of adrenal gland, unspecified
0.701 0.299 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.700 0.300 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.700 0.300 0.000
L29 Pruritus
0.700 0.300 0.000
G57.6 Lesion of plantar nerve
0.700 0.300 0.000
C50.4 Upper-outer quadrant of breast
0.699 0.301 0.000
M13.8 Other specified arthritis
0.698 0.302 0.000
M13.1 Monoarthritis, not elsewhere classified
0.698 0.302 0.000
M25 Other joint disorders, not elsewhere classified
0.698 0.302 0.000
A04.9 Bacterial intestinal infection, unspecified
0.695 0.305 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.695 0.305 0.000
A04.4 Other intestinal Escherichia coli infections
0.695 0.305 0.000
A04.3 Enterohaemorrhagic Escherichia coli infection
0.695 0.305 0.000
A04.2 Enteroinvasive Escherichia coli infection
0.695 0.305 0.000
A04.1 Enterotoxigenic Escherichia coli infection
0.695 0.305 0.000
A04.0 Enteropathogenic Escherichia coli infection
0.695 0.305 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.695 0.305 0.000
H92.2 Otorrhagia
0.695 0.305 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.695 0.305 0.000
F38 Other mood [affective] disorders
0.694 0.306 0.000
F34 Persistent mood [affective] disorders
0.694 0.306 0.000
F39 Unspecified mood [affective] disorder
0.694 0.306 0.000
M00-M03 Infectious arthropathies
0.693 0.307 0.000
H69.8 Other specified disorders of Eustachian tube
0.692 0.308 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.691 0.308 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.691 0.309 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.690 0.310 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.690 0.310 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.690 0.310 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.688 0.312 0.000
M22.4 Chondromalacia patellae
0.687 0.313 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.687 0.313 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.686 0.314 0.000
C90.2 Plasmacytoma, extramedullary
0.684 0.315 0.000
H72.8 Other perforations of tympanic membrane
0.684 0.316 0.000
M49 Spondylopathies in diseases classified elsewhere
0.683 0.317 0.000
V80-V89 Other land transport accidents
0.683 0.317 0.000
E20 Hypoparathyroidism
0.683 0.317 0.000
B15-B19 Viral hepatitis
0.683 0.317 0.000
H73 Other disorders of tympanic membrane
0.682 0.317 0.000
M48.09 Spinal stenosis (Site unspecified)
0.682 0.318 0.000
M06 Other rheumatoid arthritis
0.682 0.318 0.000
F31.8 Other bipolar affective disorders
0.681 0.319 0.000
F31.7 Bipolar affective disorder, currently in remission
0.681 0.319 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.681 0.319 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.681 0.319 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.681 0.319 0.000
E27.1 Primary adrenocortical insufficiency
0.680 0.320 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.680 0.320 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.680 0.320 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.680 0.320 0.000
E00 Congenital iodine-deficiency syndrome
0.680 0.320 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.679 0.320 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.679 0.320 0.000
E10.3 With ophthalmic complications
0.678 0.322 0.000
G95 Other diseases of spinal cord
0.678 0.322 0.000
G54.0 Brachial plexus disorders
0.678 0.322 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.677 0.322 0.000
C32 Malignant neoplasm of larynx
0.677 0.323 0.000
M46.4 Discitis, unspecified
0.677 0.323 0.000
G03 Meningitis due to other and unspecified causes
0.677 0.323 0.000
M07 Psoriatic and enteropathic arthropathies
0.677 0.323 0.000
E07 Other disorders of thyroid
0.676 0.324 0.000
Y59 Other and unspecified vaccines and biological substances
0.676 0.324 0.000
Y58 Bacterial vaccines
0.676 0.324 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.676 0.324 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.676 0.324 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.676 0.324 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.676 0.324 0.000
H65 Nonsuppurative otitis media
0.675 0.325 0.000
H93 Other disorders of ear, not elsewhere classified
0.674 0.326 0.000
M66.0 Rupture of popliteal cyst
0.673 0.327 0.000
X59 Exposure to unspecified factor
0.673 0.327 0.000
E27.8 Other specified disorders of adrenal gland
0.672 0.328 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.672 0.328 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.672 0.328 0.000
C83.7 Burkitt's tumour
0.671 0.329 0.000
C83.6 Undifferentiated (diffuse)
0.671 0.329 0.000
C83.5 Lymphoblastic (diffuse)
0.671 0.329 0.000
C83.4 Immunoblastic (diffuse)
0.671 0.329 0.000
C83.2 Mixed small and large cell (diffuse)
0.671 0.329 0.000
C83.1 Small cleaved cell (diffuse)
0.671 0.329 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.671 0.329 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.670 0.330 0.000
H60 Otitis externa
0.669 0.331 0.000
E04.0 Non-toxic diffuse goitre
0.669 0.331 0.000
W21 Striking against or struck by sports equipment
0.669 0.331 0.000
E34 Other endocrine disorders
0.668 0.332 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.668 0.332 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.668 0.332 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.333 0.000
G57.1 Meralgia paraesthetica
0.667 0.333 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.667 0.333 0.000
G30-G32 Other degenerative diseases of the nervous system
0.667 0.333 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.667 0.333 0.000
C25 Malignant neoplasm of pancreas
0.666 0.334 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.666 0.334 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.666 0.334 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
G83 Other paralytic syndromes
0.666 0.334 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.666 0.334 0.000
M66.4 Spontaneous rupture of other tendons
0.665 0.335 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.662 0.338 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.662 0.338 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.662 0.338 0.000
E32 Diseases of thymus
0.662 0.338 0.000
E31 Polyglandular dysfunction
0.662 0.338 0.000
E30 Disorders of puberty, not elsewhere classified
0.662 0.338 0.000
E26 Hyperaldosteronism
0.662 0.338 0.000
E25 Adrenogenital disorders
0.662 0.338 0.000
F60.3 Emotionally unstable personality disorder
0.661 0.339 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.661 0.339 0.000
U51 Admission status on psychiatric patients
0.661 0.339 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.660 0.340 0.000
Q00-Q07 Congenital malformations of the nervous system
0.660 0.340 0.000
C51-C58 Malignant neoplasms of female genital organs
0.659 0.341 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.658 0.341 0.000
A41.4 Septicaemia due to anaerobes
0.658 0.341 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.658 0.341 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.658 0.341 0.000
L90.5 Scar conditions and fibrosis of skin
0.658 0.342 0.000
B25-B34 Other viral diseases
0.658 0.342 0.000
M34 Systemic sclerosis
0.658 0.342 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.657 0.343 0.000
C70 Malignant neoplasm of meninges
0.657 0.343 0.000
M10 Gout
0.656 0.343 0.000
W29 Contact with other powered hand tools and household machinery
0.656 0.344 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.655 0.345 0.000
W20 Struck by thrown, projected or falling object
0.655 0.345 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.654 0.346 0.000
L89 Decubitus ulcer
0.653 0.347 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.652 0.348 0.000
L28.1 Prurigo nodularis
0.652 0.348 0.000
L25 Unspecified contact dermatitis
0.651 0.348 0.000
L24 Irritant contact dermatitis
0.651 0.348 0.000
L23 Allergic contact dermatitis
0.651 0.348 0.000
L20 Atopic dermatitis
0.651 0.348 0.000
L26 Exfoliative dermatitis
0.651 0.348 0.000
L22 Diaper [napkin] dermatitis
0.651 0.348 0.000
H74.0 Tympanosclerosis
0.651 0.348 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.650 0.350 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.647 0.353 0.000
M48.9 Spondylopathy, unspecified
0.647 0.353 0.000
M48.8 Other specified spondylopathies
0.647 0.353 0.000
M48.4 Fatigue fracture of vertebra
0.647 0.353 0.000
M48.3 Traumatic spondylopathy
0.647 0.353 0.000
M48.2 Kissing spine
0.647 0.353 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.647 0.353 0.000
L80 Vitiligo
0.646 0.354 0.000
M43 Other deforming dorsopathies
0.644 0.356 0.000
A40.9 Streptococcal septicaemia, unspecified
0.644 0.356 0.000
M46.8 Other specified inflammatory spondylopathies
0.643 0.357 0.000
M46.5 Other infective spondylopathies
0.643 0.357 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.643 0.357 0.000
M46.2 Osteomyelitis of vertebra
0.643 0.357 0.000
M46.0 Spinal enthesopathy
0.643 0.357 0.000
F33.8 Other recurrent depressive disorders
0.643 0.357 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.643 0.357 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.643 0.357 0.000
E22 Hyperfunction of pituitary gland
0.643 0.357 0.000
E06.9 Thyroiditis, unspecified
0.642 0.358 0.000
E12 Malnutrition-related diabetes mellitus
0.642 0.358 0.000
M05.8 Other seropositive rheumatoid arthritis
0.642 0.358 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.642 0.358 0.000
M05.2 Rheumatoid vasculitis
0.642 0.358 0.000
M05.1 Rheumatoid lung disease
0.642 0.358 0.000
M05.0 Felty's syndrome
0.642 0.358 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.642 0.358 0.000
L94 Other localised connective tissue disorders
0.642 0.358 0.000
L87 Transepidermal elimination disorders
0.642 0.358 0.000
L88 Pyoderma gangrenosum
0.642 0.358 0.000
L86 Keratoderma in diseases classified elsewhere
0.642 0.358 0.000
G70 Myasthenia gravis and other myoneural disorders
0.642 0.358 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.642 0.358 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.642 0.358 0.000
C65 Malignant neoplasm of renal pelvis
0.642 0.358 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.641 0.359 0.000
C92 Myeloid leukaemia
0.641 0.359 0.000
V10-V19 Pedal cyclist injured in transport accident
0.640 0.360 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.640 0.360 0.000
B65-B83 Helminthiases
0.640 0.360 0.000
Y60.0 During surgical operation
0.639 0.360 0.000
G82.4 Spastic tetraplegia
0.638 0.362 0.000
M65.8 Other synovitis and tenosynovitis
0.637 0.363 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.637 0.363 0.000
C74 Malignant neoplasm of adrenal gland
0.637 0.363 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.637 0.363 0.000
Y40.0 Penicillins
0.637 0.363 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.635 0.364 0.000
G51.8 Other disorders of facial nerve
0.635 0.364 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.634 0.365 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.634 0.365 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.634 0.365 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.634 0.365 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.634 0.365 0.000
C90.3 Solitary plasmacytoma
0.634 0.365 0.000
C90.1 Plasma cell leukaemia
0.634 0.365 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.634 0.366 0.000
C69.3 Choroid
0.634 0.366 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.634 0.366 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.634 0.366 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.633 0.367 0.000
M33 Dermatopolymyositis
0.633 0.367 0.000
M32 Systemic lupus erythematosus
0.633 0.367 0.000
M30 Polyarteritis nodosa and related conditions
0.633 0.367 0.000
C81 Hodgkin's disease
0.633 0.367 0.000
M84 Disorders of continuity of bone
0.633 0.367 0.000
M90 Osteopathies in diseases classified elsewhere
0.632 0.367 0.000
M13.93 Arthritis, unspecified (Forearm)
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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