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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35043422
log Bayes Factor = 8.72348
Chromosome 8   position 23,274,627  (GRCh37) Explore rs35043422 on Ensembl!
Variant rs35043422 is part of Cluster X0223

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
B95-B98 Bacterial, viral and other infectious agents
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.996 0.004 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.996 0.004 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.995 0.005 0.000
J90-J94 Other diseases of pleura
0.995 0.005 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
A30-A49 Other bacterial diseases
0.991 0.009 0.000
J90 Pleural effusion, not elsewhere classified
0.991 0.009 0.000
M65-M68 Disorders of synovium and tendon
0.985 0.015 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.984 0.016 0.000
S60-S69 Injuries to the wrist and hand
0.979 0.021 0.000
M20-M25 Other joint disorders
0.978 0.022 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.978 0.022 0.000
J09-J18 Influenza and pneumonia
0.965 0.035 0.000
S40-S49 Injuries to the shoulder and upper arm
0.964 0.036 0.000
M70-M79 Other soft tissue disorders
0.959 0.041 0.000
A41 Other septicaemia
0.955 0.045 0.000
A49 Bacterial infection of unspecified site
0.951 0.049 0.000
Y83.8 Other surgical procedures
0.951 0.049 0.000
M65 Synovitis and tenosynovitis
0.950 0.050 0.000
M24 Other specific joint derangements
0.945 0.055 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.941 0.059 0.000
M25 Other joint disorders, not elsewhere classified
0.938 0.062 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.934 0.066 0.000
M86-M90 Other osteopathies
0.932 0.068 0.000
Y83.6 Removal of other organ (partial) (total)
0.931 0.069 0.000
W20-W49 Exposure to inanimate mechanical forces
0.930 0.070 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.929 0.071 0.000
M05-M14 Inflammatory polyarthropathies
0.927 0.073 0.000
S90-S99 Injuries to the ankle and foot
0.925 0.075 0.000
B25-B34 Other viral diseases
0.916 0.084 0.000
M45-M49 Spondylopathies
0.915 0.085 0.000
S64 Injury of nerves at wrist and hand level
0.913 0.087 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.913 0.087 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.911 0.089 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.909 0.091 0.000
B15-B19 Viral hepatitis
0.906 0.094 0.000
A49.0 Staphylococcal infection, unspecified
0.906 0.094 0.000
Y83.3 Surgical operation with formation of external stoma
0.905 0.095 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.904 0.096 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.904 0.096 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.903 0.097 0.000
W29 Contact with other powered hand tools and household machinery
0.896 0.104 0.000
M65.3 Trigger finger
0.892 0.108 0.000
J91 Pleural effusion in conditions classified elsewhere
0.891 0.109 0.000
M25.7 Osteophyte
0.889 0.111 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.888 0.112 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.882 0.118 0.000
M66 Spontaneous rupture of synovium and tendon
0.881 0.118 0.000
M24.1 Other articular cartilage disorders
0.881 0.119 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.880 0.120 0.000
J81 Pulmonary oedema
0.880 0.120 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.878 0.122 0.000
Chapter XXII Codes for special purposes
0.877 0.123 0.000
S70-S79 Injuries to the hip and thigh
0.875 0.125 0.000
W29.9 Unspecified place
0.872 0.128 0.000
M25.9 Joint disorder, unspecified
0.870 0.130 0.000
M86 Osteomyelitis
0.870 0.130 0.000
S61 Open wound of wrist and hand
0.870 0.130 0.000
M79.7 Fibromyalgia
0.869 0.131 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.869 0.131 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.868 0.132 0.000
Chapter V Mental and behavioural disorders
0.868 0.132 0.000
M47 Spondylosis
0.867 0.133 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.866 0.134 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.861 0.139 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.859 0.141 0.000
M47.9 Spondylosis, unspecified
0.855 0.145 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.853 0.147 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.851 0.149 0.000
M14 Arthropathies in other diseases classified elsewhere
0.851 0.149 0.000
S10-S19 Injuries to the neck
0.851 0.149 0.000
M31 Other necrotising vasculopathies
0.850 0.150 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.850 0.150 0.000
M11 Other crystal arthropathies
0.850 0.150 0.000
M65.34 Trigger finger-Hand
0.850 0.150 0.000
M21 Other acquired deformities of limbs
0.848 0.152 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.846 0.154 0.000
J60-J70 Lung diseases due to external agents
0.841 0.159 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.837 0.163 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.834 0.166 0.000
M79.6 Pain in limb
0.834 0.166 0.000
A40 Streptococcal septicaemia
0.834 0.166 0.000
M65.8 Other synovitis and tenosynovitis
0.834 0.166 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.834 0.166 0.000
M40-M43 Deforming dorsopathies
0.833 0.167 0.000
J92 Pleural plaque
0.830 0.170 0.000
M24.5 Contracture of joint
0.830 0.170 0.000
S65 Injury of blood vessels at wrist and hand level
0.826 0.174 0.000
S61.0 Open wound of finger(s) without damage to nail
0.822 0.178 0.000
M71 Other bursopathies
0.822 0.178 0.000
F60-F69 Disorders of adult personality and behaviour
0.821 0.179 0.000
S41 Open wound of shoulder and upper arm
0.818 0.181 0.000
T87 Complications peculiar to reattachment and amputation
0.817 0.183 0.000
M25.77 Osteophyte (Ankle and foot)
0.817 0.183 0.000
S92 Fracture of foot, except ankle
0.815 0.185 0.000
B65-B83 Helminthiases
0.815 0.185 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.811 0.189 0.000
B34 Viral infection of unspecified site
0.811 0.189 0.000
W50-W64 Exposure to animate mechanical forces
0.809 0.191 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.809 0.191 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.809 0.191 0.000
S40 Superficial injury of shoulder and upper arm
0.808 0.192 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.808 0.192 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.807 0.193 0.000
M89 Other disorders of bone
0.807 0.193 0.000
M30 Polyarteritis nodosa and related conditions
0.807 0.193 0.000
T17 Foreign body in respiratory tract
0.805 0.195 0.000
V20-V29 Motorcycle rider injured in transport accident
0.804 0.196 0.000
M86.9 Osteomyelitis, unspecified
0.804 0.196 0.000
J15.2 Pneumonia due to staphylococcus
0.801 0.199 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.801 0.199 0.000
M14.6 Neuropathic arthropathy
0.797 0.203 0.000
T85.2 Mechanical complication of intraocular lens
0.795 0.205 0.000
M11.2 Other chondrocalcinosis
0.795 0.205 0.000
X50-X57 Overexertion, travel and privation
0.793 0.207 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.792 0.208 0.000
M31.6 Other giant cell arteritis
0.792 0.208 0.000
V70-V79 Bus occupant injured in transport accident
0.790 0.210 0.000
M25.0 Haemarthrosis
0.790 0.210 0.000
S42 Fracture of shoulder and upper arm
0.790 0.210 0.000
F60 Specific personality disorders
0.788 0.212 0.000
M25.4 Effusion of joint
0.787 0.213 0.000
S71 Open wound of hip and thigh
0.786 0.214 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.785 0.215 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.784 0.216 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.784 0.216 0.000
M24.0 Loose body in joint
0.783 0.217 0.000
M91-M94 Chondropathies
0.783 0.217 0.000
V10-V19 Pedal cyclist injured in transport accident
0.783 0.217 0.000
S69 Other and unspecified injuries of wrist and hand
0.782 0.218 0.000
S64.3 Injury of digital nerve of thumb
0.781 0.219 0.000
M46 Other inflammatory spondylopathies
0.780 0.220 0.000
S64.4 Injury of digital nerve of other finger
0.780 0.220 0.000
M79.1 Myalgia
0.778 0.222 0.000
B18 Chronic viral hepatitis
0.778 0.222 0.000
T79-T79 Certain early complications of trauma
0.777 0.223 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.776 0.224 0.000
M66.4 Spontaneous rupture of other tendons
0.776 0.224 0.000
X20-X29 Contact with venomous animals and plants
0.774 0.226 0.000
V98-V99 Other and unspecified transport accidents
0.773 0.227 0.000
M79.70 Fibromyalgia (Multiple sites)
0.770 0.230 0.000
W22 Striking against or struck by other objects
0.767 0.233 0.000
S68 Traumatic amputation of wrist and hand
0.767 0.233 0.000
M13 Other arthritis
0.766 0.234 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.766 0.234 0.000
J94 Other pleural conditions
0.765 0.235 0.000
M25.78 Osteophyte (Other)
0.765 0.235 0.000
M77 Other enthesopathies
0.764 0.236 0.000
S91 Open wound of ankle and foot
0.764 0.236 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.763 0.237 0.000
X10-X19 Contact with heat and hot substances
0.763 0.237 0.000
T66-T78 Other and unspecified effects of external causes
0.762 0.238 0.000
M65.1 Other infective (teno)synovitis
0.762 0.238 0.000
M00-M03 Infectious arthropathies
0.759 0.240 0.000
B50-B64 Protozoal diseases
0.759 0.241 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.757 0.243 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.756 0.244 0.000
M67 Other disorders of synovium and tendon
0.755 0.244 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.755 0.245 0.000
T00-T07 Injuries involving multiple body regions
0.751 0.249 0.000
M79.5 Residual foreign body in soft tissue
0.748 0.252 0.000
A41.8 Other specified septicaemia
0.748 0.252 0.000
A49.8 Other bacterial infections of unspecified site
0.748 0.252 0.000
M25.94 Joint disorder, unspecified (Hand)
0.747 0.253 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.746 0.254 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.745 0.255 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.744 0.256 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.743 0.257 0.000
J92.0 Pleural plaque with presence of asbestos
0.743 0.257 0.000
F60.3 Emotionally unstable personality disorder
0.742 0.258 0.000
M79.79 Fibromyalgia (Site unspecified)
0.742 0.258 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.742 0.258 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.741 0.259 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.741 0.259 0.000
A49.9 Bacterial infection, unspecified
0.741 0.259 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.740 0.260 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.739 0.261 0.000
W45 Foreign body or object entering through skin
0.739 0.261 0.000
J15.5 Pneumonia due to Escherichia coli
0.735 0.265 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.733 0.267 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.733 0.267 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.733 0.267 0.000
X60-X84 Intentional self-harm
0.733 0.267 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.733 0.267 0.000
B19 Unspecified viral hepatitis
0.732 0.268 0.000
J18 Pneumonia, organism unspecified
0.732 0.268 0.000
S70 Superficial injury of hip and thigh
0.731 0.269 0.000
F99-F99 Unspecified mental disorder
0.730 0.269 0.000
T86 Failure and rejection of transplanted organs and tissues
0.730 0.270 0.000
B27 Infectious mononucleosis
0.730 0.270 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.729 0.271 0.000
M60-M63 Disorders of muscles
0.729 0.271 0.000
J12 Viral pneumonia, not elsewhere classified
0.727 0.273 0.000
T18 Foreign body in alimentary tract
0.726 0.274 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.726 0.274 0.000
S19 Other and unspecified injuries of neck
0.725 0.275 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.723 0.277 0.000
S71.1 Open wound of thigh
0.723 0.277 0.000
V80-V89 Other land transport accidents
0.723 0.277 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.722 0.278 0.000
M24.54 Contracture of joint (Hand)
0.720 0.280 0.000
B34.9 Viral infection, unspecified
0.720 0.280 0.000
A15-A19 Tuberculosis
0.719 0.281 0.000
T17.2 Foreign body in pharynx
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
M25.8 Other specified joint disorders
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
B91 Sequelae of poliomyelitis
0.715 0.285 0.000
M24.7 Protrusio acetabuli
0.714 0.286 0.000
S41.1 Open wound of upper arm
0.714 0.286 0.000
J86 Pyothorax
0.713 0.287 0.000
B15 Acute hepatitis A
0.712 0.288 0.000
T14 Injury of unspecified body region
0.712 0.288 0.000
B25 Cytomegaloviral disease
0.711 0.289 0.000
A44 Bartonellosis
0.711 0.289 0.000
A43 Nocardiosis
0.711 0.289 0.000
A42 Actinomycosis
0.711 0.289 0.000
A39 Meningococcal infection
0.711 0.289 0.000
A37 Whooping cough
0.711 0.289 0.000
A36 Diphtheria
0.711 0.289 0.000
A32 Listeriosis
0.711 0.289 0.000
A31 Infection due to other mycobacteria
0.711 0.289 0.000
A30 Leprosy [Hansen's disease]
0.711 0.289 0.000
A38 Scarlet fever
0.711 0.289 0.000
A35 Other tetanus
0.711 0.289 0.000
A34 Obstetrical tetanus
0.711 0.289 0.000
A33 Tetanus neonatorum
0.711 0.289 0.000
Y00-Y09 Assault
0.710 0.290 0.000
J18.1 Lobar pneumonia, unspecified
0.709 0.291 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.708 0.292 0.000
S61.8 Open wound of other parts of wrist and hand
0.707 0.293 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.706 0.294 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.706 0.294 0.000
S60 Superficial injury of wrist and hand
0.705 0.295 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.704 0.296 0.000
M21.4 Flat foot [pes planus] (acquired)
0.703 0.297 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.703 0.297 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.702 0.298 0.000
T93 Sequelae of injuries of lower limb
0.702 0.298 0.000
M25.76 Osteophyte (Lower leg)
0.702 0.298 0.000
M79.9 Soft tissue disorder, unspecified
0.702 0.298 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.299 0.000
J85 Abscess of lung and mediastinum
0.701 0.299 0.000
M90 Osteopathies in diseases classified elsewhere
0.699 0.301 0.000
T25 Burn and corrosion of ankle and foot
0.698 0.302 0.000
S65.0 Injury of ulnar artery at wrist and hand level
0.697 0.303 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.695 0.305 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.694 0.306 0.000
J14 Pneumonia due to Haemophilus influenzae
0.694 0.306 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.694 0.306 0.000
T91 Sequelae of injuries of neck and trunk
0.693 0.307 0.000
M34 Systemic sclerosis
0.692 0.308 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.692 0.308 0.000
J09 Influenza due to certain identified influenza virus
0.692 0.308 0.000
S48 Traumatic amputation of shoulder and upper arm
0.691 0.309 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.691 0.309 0.000
S44 Injury of nerves at shoulder and upper arm level
0.691 0.309 0.000
S47 Crushing injury of shoulder and upper arm
0.691 0.309 0.000
U88 Agent resistant to multiple antibiotics
0.689 0.311 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.688 0.312 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.687 0.313 0.000
J15.1 Pneumonia due to Pseudomonas
0.686 0.314 0.000
M33 Dermatopolymyositis
0.685 0.315 0.000
J64 Unspecified pneumoconiosis
0.685 0.315 0.000
A41.4 Septicaemia due to anaerobes
0.685 0.315 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.685 0.315 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.684 0.316 0.000
M25.06 Haemarthrosis (Lower leg)
0.683 0.317 0.000
T68 Hypothermia
0.683 0.317 0.000
B80 Enterobiasis
0.682 0.318 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.682 0.318 0.000
A49.3 Mycoplasma infection, unspecified
0.682 0.318 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.682 0.318 0.000
S10 Superficial injury of neck
0.682 0.318 0.000
M65.2 Calcific tendinitis
0.681 0.318 0.000
M65.0 Abscess of tendon sheath
0.681 0.318 0.000
J17 Pneumonia in diseases classified elsewhere
0.679 0.320 0.000
M24.9 Joint derangement, unspecified
0.677 0.323 0.000
M24.6 Ankylosis of joint
0.677 0.323 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.677 0.323 0.000
A40.9 Streptococcal septicaemia, unspecified
0.677 0.323 0.000
J15.4 Pneumonia due to other streptococci
0.677 0.323 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.677 0.323 0.000
M25.47 Effusion of joint (Ankle and foot)
0.676 0.324 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.676 0.324 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.675 0.325 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.675 0.325 0.000
M79.3 Panniculitis, unspecified
0.674 0.326 0.000
M66.0 Rupture of popliteal cyst
0.674 0.326 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.673 0.326 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.673 0.327 0.000
M25.2 Flail joint
0.673 0.327 0.000
M25.1 Fistula of joint
0.673 0.327 0.000
M41 Scoliosis
0.672 0.328 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.672 0.328 0.000
S64.1 Injury of median nerve at wrist and hand level
0.672 0.328 0.000
M86.6 Other chronic osteomyelitis
0.671 0.329 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.670 0.329 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.670 0.329 0.000
M66.2 Spontaneous rupture of extensor tendons
0.670 0.330 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.670 0.330 0.000
S11 Open wound of neck
0.670 0.330 0.000
M24.07 Loose body in joint (Ankle and foot)
0.670 0.330 0.000
B18.2 Chronic viral hepatitis C
0.669 0.331 0.000
M21.0 Valgus deformity, not elsewhere classified
0.669 0.331 0.000
V40-V49 Car occupant injured in transport accident
0.667 0.332 0.000
A40.8 Other streptococcal septicaemia
0.667 0.333 0.000
Q80-Q89 Other congenital malformations
0.667 0.333 0.000
W46 Contact with hypodermic needle
0.667 0.333 0.000
W43 Exposure to vibration
0.667 0.333 0.000
W42 Exposure to noise
0.667 0.333 0.000
W41 Exposure to high-pressure jet
0.667 0.333 0.000
W40 Explosion of other materials
0.667 0.333 0.000
W39 Discharge of firework
0.667 0.333 0.000
W38 Explosion and rupture of other specified pressurised devices
0.667 0.333 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.667 0.333 0.000
W36 Explosion and rupture of gas cylinder
0.667 0.333 0.000
W35 Explosion and rupture of boiler
0.667 0.333 0.000
W34 Discharge from other and unspecified firearms
0.667 0.333 0.000
W33 Rifle, shotgun and larger firearm discharge
0.667 0.333 0.000
W32 Handgun discharge
0.667 0.333 0.000
W31 Contact with other and unspecified machinery
0.667 0.333 0.000
W30 Contact with agricultural machinery
0.667 0.333 0.000
W28 Contact with powered lawn mower
0.667 0.333 0.000
W27 Contact with nonpowered hand tool
0.667 0.333 0.000
W26 Contact with knife, sword or dagger
0.667 0.333 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.667 0.333 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.665 0.335 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.665 0.335 0.000
M32 Systemic lupus erythematosus
0.665 0.335 0.000
T98 Sequelae of other and unspecified effects of external causes
0.665 0.335 0.000
M12 Other specific arthropathies
0.665 0.335 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.665 0.335 0.000
M08 Juvenile arthritis
0.665 0.335 0.000
A49.1 Streptococcal infection, unspecified
0.664 0.336 0.000
Y83.5 Amputation of limb(s)
0.664 0.336 0.000
W44 Foreign body entering into or through eye or natural orifice
0.663 0.336 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.663 0.337 0.000
S98 Traumatic amputation of ankle and foot
0.663 0.337 0.000
S97 Crushing injury of ankle and foot
0.663 0.337 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.663 0.337 0.000
S95 Injury of blood vessels at ankle and foot level
0.663 0.337 0.000
S94 Injury of nerves at ankle and foot level
0.663 0.337 0.000
M86.8 Other osteomyelitis
0.663 0.337 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.662 0.338 0.000
M89.8 Other specified disorders of bone
0.661 0.339 0.000
B17 Other acute viral hepatitis
0.660 0.340 0.000
T87.3 Neuroma of amputation stump
0.659 0.341 0.000
M43 Other deforming dorsopathies
0.658 0.342 0.000
B33 Other viral diseases, not elsewhere classified
0.657 0.343 0.000
B30 Viral conjunctivitis
0.657 0.343 0.000
B26 Mumps
0.657 0.343 0.000
S99 Other and unspecified injuries of ankle and foot
0.657 0.343 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.655 0.345 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.655 0.345 0.000
S64.8 Injury of other nerves at wrist and hand level
0.655 0.345 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.655 0.345 0.000
M13.8 Other specified arthritis
0.655 0.345 0.000
B35-B49 Mycoses
0.655 0.345 0.000
J15.9 Bacterial pneumonia, unspecified
0.654 0.345 0.000
J15.8 Other bacterial pneumonia
0.654 0.345 0.000
J15.3 Pneumonia due to streptococcus, group B
0.654 0.345 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.654 0.346 0.000
F30-F39 Mood [affective] disorders
0.654 0.346 0.000
M76 Enthesopathies of lower limb, excluding foot
0.654 0.346 0.000
M79.18 Myalgia (Other)
0.653 0.347 0.000
T17.5 Foreign body in bronchus
0.652 0.347 0.000
M24.56 Contracture of joint (Lower leg)
0.652 0.348 0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.652 0.348 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.652 0.348 0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.652 0.348 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.652 0.348 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.652 0.348 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.652 0.348 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.652 0.348 0.000
A48 Other bacterial diseases, not elsewhere classified
0.652 0.348 0.000
W22.9 Unspecified place
0.651 0.349 0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)
0.651 0.349 0.000
M79.8 Other specified soft tissue disorders
0.651 0.349 0.000
T21 Burn and corrosion of trunk
0.651 0.349 0.000
F60.6 Anxious [avoidant] personality disorder
0.650 0.350 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.650 0.350 0.000
S92.5 Fracture of other toe
0.650 0.350 0.000
S63.3 Traumatic rupture of ligament of wrist and carpus
0.649 0.351 0.000
M25.74 Osteophyte (Hand)
0.649 0.351 0.000
T87.4 Infection of amputation stump
0.649 0.351 0.000
T19 Foreign body in genito-urinary tract
0.648 0.352 0.000
T15 Foreign body on external eye
0.648 0.352 0.000
T16 Foreign body in ear
0.648 0.352 0.000
M45 Ankylosing spondylitis
0.648 0.352 0.000
J10 Influenza due to identified influenza virus
0.648 0.352 0.000
M79.0 Rheumatism, unspecified
0.646 0.353 0.000
M89.0 Algoneurodystrophy
0.646 0.353 0.000
S43.1 Dislocation of acromioclavicular joint
0.646 0.354 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.645 0.355 0.000
T11 Other injuries of upper limb, level unspecified
0.645 0.355 0.000
X51 Travel and motion
0.645 0.355 0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)
0.644 0.356 0.000
S92.2 Fracture of other tarsal bone(s)
0.643 0.357 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.643 0.357 0.000
J70 Respiratory conditions due to other external agents
0.643 0.357 0.000
W29.8 Other specified place
0.642 0.357 0.000
W29.6 Industrial and construction area
0.642 0.357 0.000
W29.0 Home
0.642 0.357 0.000
W29.7 Farm
0.642 0.357 0.000
W29.5 Trade and service area
0.642 0.357 0.000
W29.4 Street and highway
0.642 0.357 0.000
W29.3 Sports and athletics area
0.642 0.357 0.000
W29.2 School, other institution and public administrative area
0.642 0.357 0.000
W29.1 Residential institution
0.642 0.357 0.000
M49 Spondylopathies in diseases classified elsewhere
0.642 0.358 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.642 0.358 0.000
V78 Bus occupant injured in noncollision transport accident
0.641 0.358 0.000
S69.9 Unspecified injury of wrist and hand
0.641 0.358 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.641 0.359 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.641 0.359 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.640 0.360 0.000
M67.8 Other specified disorders of synovium and tendon
0.640 0.360 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.640 0.360 0.000
S92.4 Fracture of great toe
0.640 0.360 0.000
M65.39 Trigger finger-Site unspec
0.639 0.361 0.000
M65.38 Trigger finger-Other
0.639 0.361 0.000
M65.37 Trigger finger-Ankle/foot
0.639 0.361 0.000
M65.36 Trigger finger-Lower leg
0.639 0.361 0.000
M65.35 Trigger finger-Pelvic/thigh
0.639 0.361 0.000
M65.33 Trigger finger-Forearm
0.639 0.361 0.000
M65.32 Trigger finger-Upper arm
0.639 0.361 0.000
M65.31 Trigger finger-Shldr region
0.639 0.361 0.000
M65.30 Trigger finger-Mult sites
0.639 0.361 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.639 0.361 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.638 0.362 0.000
M79.11 Myalgia (Shoulder region)
0.638 0.362 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.637 0.363 0.000
M25.79 Osteophyte (Site unspecified)
0.637 0.363 0.000
M25.73 Osteophyte (Forearm)
0.637 0.363 0.000
M25.70 Osteophyte (Multiple sites)
0.637 0.363 0.000
S61.7 Multiple open wounds of wrist and hand
0.636 0.364 0.000
M71.3 Other bursal cyst
0.636 0.364 0.000
S90 Superficial injury of ankle and foot
0.635 0.364 0.000
B16 Acute hepatitis B
0.635 0.365 0.000
M35 Other systemic involvement of connective tissue
0.635 0.365 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.635 0.365 0.000
M80-M85 Disorders of bone density and structure
0.635 0.365 0.000
F70-F79 Mental retardation
0.635 0.365 0.000
M24.2 Disorder of ligament
0.635 0.365 0.000
Q00-Q07 Congenital malformations of the nervous system
0.634 0.366 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.634 0.366 0.000
Chapter VIII Diseases of the ear and mastoid process
0.634 0.366 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.634 0.366 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.632 0.367 0.000
S65.1 Injury of radial artery at wrist and hand level
0.632 0.368 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.632 0.368 0.000
M66.3 Spontaneous rupture of flexor tendons
0.632 0.368 0.000
M66.1 Rupture of synovium
0.632 0.368 0.000
F99 Mental disorder, not otherwise specified
0.632 0.368 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.632 0.368 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.631 0.369 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.631 0.369 0.000
M24.18 Other articular cartilage disorders (Other)
0.631 0.369 0.000
M24.14 Other articular cartilage disorders (Hand)
0.631 0.369 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.631 0.369 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.631 0.369 0.000
M25.83 Other specified joint disorders (Forearm)
0.631 0.369 0.000
T20 Burn and corrosion of head and neck
0.630 0.370 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.629 0.371 0.000
U89 Agent resistant to other and unspecified antibiotics
0.629 0.371 0.000
M24.01 Loose body in joint (Shoulder region)
0.628 0.372 0.000
W20 Struck by thrown, projected or falling object
0.627 0.372 0.000
M65.14 Other infective (teno)synovitis (Hand)
0.627 0.373 0.000
S78 Traumatic amputation of hip and thigh
0.627 0.373 0.000
S77 Crushing injury of hip and thigh
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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