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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35048777
log Bayes Factor = 13.7061
Chromosome 13   position 77,288,433  (GRCh37) Explore rs35048777 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.994 0.006 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.994 0.006 0.000
I25.2 Old myocardial infarction
0.993 0.007 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.984 0.016 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.980 0.020 0.000
I20 Angina pectoris
0.975 0.025 0.000
K80 Cholelithiasis
0.975 0.025 0.000
J40-J47 Chronic lower respiratory diseases
0.970 0.030 0.000
N60-N64 Disorders of breast
0.969 0.031 0.000
H30-H36 Disorders of choroid and retina
0.965 0.035 0.000
I21 Acute myocardial infarction
0.962 0.038 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.960 0.040 0.000
N80 Endometriosis
0.959 0.041 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.958 0.042 0.000
H53-H54 Visual disturbances and blindness
0.955 0.045 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.954 0.046 0.000
J44 Other chronic obstructive pulmonary disease
0.953 0.047 0.000
I20.9 Angina pectoris, unspecified
0.944 0.056 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.944 0.056 0.000
D60-D64 Aplastic and other anaemias
0.942 0.058 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.940 0.060 0.000
I30-I52 Other forms of heart disease
0.938 0.062 0.000
N10-N16 Renal tubulo-interstitial diseases
0.935 0.065 0.000
J30-J39 Other diseases of upper respiratory tract
0.933 0.067 0.000
N92 Excessive, frequent and irregular menstruation
0.930 0.070 0.000
N63 Unspecified lump in breast
0.921 0.079 0.000
N88 Other noninflammatory disorders of cervix uteri
0.917 0.083 0.000
N83.2 Other and unspecified ovarian cysts
0.917 0.083 0.000
S60-S69 Injuries to the wrist and hand
0.916 0.084 0.000
H54 Blindness and low vision
0.912 0.088 0.000
D64 Other anaemias
0.910 0.090 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.909 0.091 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.907 0.093 0.000
H36 Retinal disorders in diseases classified elsewhere
0.901 0.099 0.000
S80-S89 Injuries to the knee and lower leg
0.901 0.099 0.000
K50-K52 Noninfective enteritis and colitis
0.897 0.103 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.896 0.104 0.000
N17-N19 Renal failure
0.893 0.107 0.000
I10-I15 Hypertensive diseases
0.889 0.111 0.000
N95 Menopausal and other perimenopausal disorders
0.887 0.113 0.000
D64.9 Anaemia, unspecified
0.887 0.113 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.886 0.114 0.000
I25.1 Atherosclerotic heart disease
0.882 0.118 0.000
K86 Other diseases of pancreas
0.869 0.131 0.000
N61 Inflammatory disorders of breast
0.869 0.131 0.000
K70-K77 Diseases of liver
0.868 0.132 0.000
J00-J06 Acute upper respiratory infections
0.868 0.132 0.000
Chapter XX External causes of morbidity and mortality
0.866 0.134 0.000
N00-N08 Glomerular diseases
0.863 0.137 0.000
N13 Obstructive and reflux uropathy
0.861 0.139 0.000
I20.0 Unstable angina
0.858 0.142 0.000
K40-K46 Hernia
0.857 0.143 0.000
H36.0 Diabetic retinopathy
0.856 0.144 0.000
J35 Chronic diseases of tonsils and adenoids
0.845 0.155 0.000
I50 Heart failure
0.843 0.157 0.000
N80.1 Endometriosis of ovary
0.842 0.158 0.000
Chapter XXII Codes for special purposes
0.839 0.161 0.000
J95-J99 Other diseases of the respiratory system
0.839 0.161 0.000
K81 Cholecystitis
0.839 0.161 0.000
K50 Crohn's disease [regional enteritis]
0.835 0.165 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.833 0.167 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.832 0.168 0.000
I24 Other acute ischaemic heart diseases
0.831 0.169 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.830 0.170 0.000
H35 Other retinal disorders
0.830 0.170 0.000
N80.9 Endometriosis, unspecified
0.829 0.171 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.828 0.172 0.000
H34 Retinal vascular occlusions
0.827 0.173 0.000
N97 Female infertility
0.826 0.174 0.000
N18 Chronic renal failure
0.819 0.181 0.000
J38.3 Other diseases of vocal cords
0.818 0.182 0.000
N84 Polyp of female genital tract
0.817 0.183 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.812 0.188 0.000
J90-J94 Other diseases of pleura
0.810 0.190 0.000
H54.7 Unspecified visual loss
0.810 0.190 0.000
H25-H28 Disorders of lens
0.808 0.192 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.806 0.194 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.802 0.198 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.800 0.200 0.000
S20-S29 Injuries to the thorax
0.800 0.200 0.000
D70 Agranulocytosis
0.799 0.201 0.000
K80.4 Calculus of bile duct with cholecystitis
0.799 0.201 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.797 0.203 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.797 0.203 0.000
I11 Hypertensive heart disease
0.795 0.205 0.000
N95.1 Menopausal and female climacteric states
0.794 0.206 0.000
I51 Complications and ill-defined descriptions of heart disease
0.794 0.206 0.000
J38.7 Other diseases of larynx
0.794 0.206 0.000
J00 Acute nasopharyngitis [common cold]
0.790 0.210 0.000
I34 Nonrheumatic mitral valve disorders
0.788 0.212 0.000
J35.1 Hypertrophy of tonsils
0.788 0.212 0.000
I44 Atrioventricular and left bundle-branch block
0.785 0.215 0.000
N80.3 Endometriosis of pelvic peritoneum
0.782 0.218 0.000
N83.1 Corpus luteum cyst
0.779 0.221 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.777 0.223 0.000
H53 Visual disturbances
0.776 0.224 0.000
J42 Unspecified chronic bronchitis
0.775 0.225 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.775 0.225 0.000
Chapter VI Diseases of the nervous system
0.773 0.227 0.000
T79-T79 Certain early complications of trauma
0.772 0.228 0.000
K50.9 Crohn's disease, unspecified
0.769 0.231 0.000
N84.0 Polyp of corpus uteri
0.767 0.233 0.000
N99-N99 Other disorders of the genitourinary system
0.766 0.234 0.000
N80.2 Endometriosis of Fallopian tube
0.766 0.234 0.000
K31 Other diseases of stomach and duodenum
0.765 0.235 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.765 0.235 0.000
I25.3 Aneurysm of heart
0.764 0.235 0.000
J40 Bronchitis, not specified as acute or chronic
0.762 0.238 0.000
N94.1 Dyspareunia
0.761 0.239 0.000
K75 Other inflammatory liver diseases
0.758 0.242 0.000
H54.9 Unspecified visual impairment (binocular)
0.757 0.243 0.000
H10-H13 Disorders of conjunctiva
0.756 0.244 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.755 0.245 0.000
H54.0 Blindness, both eyes
0.755 0.245 0.000
S70-S79 Injuries to the hip and thigh
0.752 0.248 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.752 0.248 0.000
J90 Pleural effusion, not elsewhere classified
0.752 0.248 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.751 0.249 0.000
I50.1 Left ventricular failure
0.749 0.251 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.749 0.251 0.000
K82 Other diseases of gallbladder
0.747 0.253 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.746 0.254 0.000
D55-D59 Haemolytic anaemias
0.746 0.254 0.000
K85 Acute pancreatitis
0.746 0.254 0.000
I38 Endocarditis, valve unspecified
0.745 0.255 0.000
S81 Open wound of lower leg
0.744 0.256 0.000
K43 Ventral hernia
0.744 0.256 0.000
N88.2 Stricture and stenosis of cervix uteri
0.742 0.258 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.740 0.260 0.000
N18.2 Chronic kidney disease, stage 2
0.738 0.262 0.000
I10 Essential (primary) hypertension
0.737 0.263 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.737 0.263 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.737 0.263 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.735 0.265 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.734 0.266 0.000
N60 Benign mammary dysplasia
0.734 0.266 0.000
K65-K67 Diseases of peritoneum
0.732 0.268 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.731 0.269 0.000
I22 Subsequent myocardial infarction
0.729 0.271 0.000
H34.8 Other retinal vascular occlusions
0.728 0.272 0.000
I35 Nonrheumatic aortic valve disorders
0.728 0.272 0.000
I50.0 Congestive heart failure
0.728 0.272 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.728 0.272 0.000
K86.8 Other specified diseases of pancreas
0.727 0.273 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.726 0.274 0.000
W20-W49 Exposure to inanimate mechanical forces
0.726 0.274 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.726 0.274 0.000
K42 Umbilical hernia
0.725 0.275 0.000
J38.4 Oedema of larynx
0.725 0.275 0.000
K83 Other diseases of biliary tract
0.724 0.276 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.723 0.277 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.721 0.279 0.000
I05-I09 Chronic rheumatic heart diseases
0.721 0.279 0.000
S32 Fracture of lumbar spine and pelvis
0.720 0.280 0.000
S62 Fracture at wrist and hand level
0.720 0.280 0.000
D75 Other diseases of blood and blood-forming organs
0.719 0.281 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.719 0.281 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.716 0.284 0.000
J60-J70 Lung diseases due to external agents
0.716 0.284 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.716 0.284 0.000
K76 Other diseases of liver
0.716 0.284 0.000
H55-H59 Other disorders of eye and adnexa
0.716 0.284 0.000
S64 Injury of nerves at wrist and hand level
0.715 0.285 0.000
N98 Complications associated with artificial fertilisation
0.715 0.285 0.000
N91 Absent, scanty and rare menstruation
0.715 0.285 0.000
N82 Fistulae involving female genital tract
0.715 0.285 0.000
N96 Habitual aborter
0.715 0.285 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.715 0.285 0.000
K31.8 Other specified diseases of stomach and duodenum
0.714 0.286 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.713 0.287 0.000
N11 Chronic tubulo-interstitial nephritis
0.713 0.287 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.713 0.287 0.000
N80.0 Endometriosis of uterus
0.713 0.287 0.000
K80.8 Other cholelithiasis
0.712 0.288 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.710 0.290 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.707 0.293 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.706 0.294 0.000
I44.7 Left bundle-branch block, unspecified
0.706 0.294 0.000
H25 Senile cataract
0.706 0.294 0.000
N13.4 Hydroureter
0.705 0.295 0.000
I25.5 Ischaemic cardiomyopathy
0.704 0.296 0.000
J98 Other respiratory disorders
0.704 0.296 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.704 0.296 0.000
K55-K64 Other diseases of intestines
0.704 0.296 0.000
N97.9 Female infertility, unspecified
0.704 0.296 0.000
H54.4 Blindness, one eye
0.703 0.296 0.000
T33-T35 Frostbite
0.703 0.297 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.297 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.703 0.297 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.703 0.297 0.000
T00-T07 Injuries involving multiple body regions
0.703 0.297 0.000
S10-S19 Injuries to the neck
0.703 0.297 0.000
H43-H45 Disorders of vitreous body and globe
0.703 0.297 0.000
H53.8 Other visual disturbances
0.702 0.298 0.000
N19 Unspecified renal failure
0.701 0.299 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.700 0.300 0.000
N83.0 Follicular cyst of ovary
0.700 0.300 0.000
K21 Gastro-oesophageal reflux disease
0.699 0.301 0.000
I20.1 Angina pectoris with documented spasm
0.699 0.301 0.000
K80.3 Calculus of bile duct with cholangitis
0.699 0.301 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.698 0.302 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.696 0.304 0.000
J38.0 Paralysis of vocal cords and larynx
0.696 0.304 0.000
K81.1 Chronic cholecystitis
0.696 0.304 0.000
J41 Simple and mucopurulent chronic bronchitis
0.695 0.305 0.000
J46 Status asthmaticus
0.695 0.305 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.694 0.305 0.000
J38.1 Polyp of vocal cord and larynx
0.693 0.307 0.000
H25.9 Senile cataract, unspecified
0.693 0.307 0.000
I34.0 Mitral (valve) insufficiency
0.693 0.307 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.693 0.307 0.000
D50-D53 Nutritional anaemias
0.692 0.308 0.000
N02 Recurrent and persistent haematuria
0.692 0.308 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.691 0.308 0.000
H31 Other disorders of choroid
0.691 0.308 0.000
H30 Chorioretinal inflammation
0.691 0.308 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.690 0.310 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.690 0.310 0.000
D73 Diseases of spleen
0.689 0.311 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.689 0.311 0.000
N83.7 Haematoma of broad ligament
0.689 0.311 0.000
N83.6 Haematosalpinx
0.689 0.311 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.689 0.311 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.689 0.311 0.000
E10-E14 Diabetes mellitus
0.688 0.312 0.000
N80.6 Endometriosis in cutaneous scar
0.688 0.312 0.000
N80.5 Endometriosis of intestine
0.688 0.312 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.688 0.312 0.000
S80 Superficial injury of lower leg
0.686 0.314 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.686 0.314 0.000
W00-W19 Falls
0.686 0.314 0.000
N95.0 Postmenopausal bleeding
0.686 0.314 0.000
S50-S59 Injuries to the elbow and forearm
0.684 0.316 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.684 0.316 0.000
J39 Other diseases of upper respiratory tract
0.684 0.316 0.000
K75.4 Autoimmune hepatitis
0.683 0.316 0.000
J32 Chronic sinusitis
0.683 0.317 0.000
N13.3 Other and unspecified hydronephrosis
0.683 0.317 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.682 0.318 0.000
S61 Open wound of wrist and hand
0.680 0.320 0.000
N92.3 Ovulation bleeding
0.678 0.322 0.000
N18.0 End-stage renal disease
0.678 0.322 0.000
K50.8 Other Crohn's disease
0.677 0.323 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.676 0.324 0.000
D80-D89 Certain disorders involving the immune mechanism
0.676 0.324 0.000
N64 Other disorders of breast
0.676 0.324 0.000
S90-S99 Injuries to the ankle and foot
0.675 0.324 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.675 0.325 0.000
I52 Other heart disorders in diseases classified elsewhere
0.673 0.327 0.000
I48 Atrial fibrillation and flutter
0.673 0.327 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.673 0.327 0.000
I41 Myocarditis in diseases classified elsewhere
0.673 0.327 0.000
I40 Acute myocarditis
0.673 0.327 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.673 0.327 0.000
I37 Pulmonary valve disorders
0.673 0.327 0.000
I36 Nonrheumatic tricuspid valve disorders
0.673 0.327 0.000
I33 Acute and subacute endocarditis
0.673 0.327 0.000
I32 Pericarditis in diseases classified elsewhere
0.673 0.327 0.000
I30 Acute pericarditis
0.673 0.327 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.672 0.328 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.670 0.329 0.000
N15 Other renal tubulo-interstitial diseases
0.670 0.329 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.670 0.329 0.000
N10 Acute tubulo-interstitial nephritis
0.670 0.329 0.000
S89 Other and unspecified injuries of lower leg
0.670 0.330 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.670 0.330 0.000
S60 Superficial injury of wrist and hand
0.670 0.330 0.000
J37 Chronic laryngitis and laryngotracheitis
0.669 0.331 0.000
J02 Acute pharyngitis
0.668 0.332 0.000
N92.5 Other specified irregular menstruation
0.667 0.333 0.000
N92.2 Excessive menstruation at puberty
0.667 0.333 0.000
N70 Salpingitis and oophoritis
0.666 0.334 0.000
K86.9 Disease of pancreas, unspecified
0.666 0.334 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.664 0.336 0.000
K72 Hepatic failure, not elsewhere classified
0.664 0.336 0.000
K55 Vascular disorders of intestine
0.664 0.336 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.664 0.336 0.000
T66-T78 Other and unspecified effects of external causes
0.663 0.337 0.000
H35.8 Other specified retinal disorders
0.663 0.337 0.000
H35.5 Hereditary retinal dystrophy
0.662 0.338 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.662 0.338 0.000
I31 Other diseases of pericardium
0.660 0.340 0.000
S67 Crushing injury of wrist and hand
0.659 0.341 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.659 0.341 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.657 0.342 0.000
N88.4 Hypertrophic elongation of cervix uteri
0.657 0.342 0.000
N88.3 Incompetence of cervix uteri
0.657 0.342 0.000
N88.1 Old laceration of cervix uteri
0.657 0.342 0.000
N88.0 Leukoplakia of cervix uteri
0.657 0.342 0.000
S69 Other and unspecified injuries of wrist and hand
0.657 0.343 0.000
S65 Injury of blood vessels at wrist and hand level
0.657 0.343 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.657 0.343 0.000
K81.0 Acute cholecystitis
0.657 0.343 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.657 0.343 0.000
D62 Acute posthaemorrhagic anaemia
0.656 0.344 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.654 0.346 0.000
H54.6 Unqualified visual loss, one eye
0.654 0.346 0.000
H54.5 Low vision, one eye
0.654 0.346 0.000
H54.3 Unqualified visual loss, both eyes
0.654 0.346 0.000
H54.2 Low vision, both eyes
0.654 0.346 0.000
H54.1 Blindness, one eye, low vision, other eye
0.654 0.346 0.000
D61 Other aplastic anaemias
0.654 0.346 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.653 0.346 0.000
D64.8 Other specified anaemias
0.652 0.348 0.000
D64.4 Congenital dyserythropoietic anaemia
0.652 0.348 0.000
D64.3 Other sideroblastic anaemias
0.652 0.348 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.652 0.348 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.652 0.348 0.000
D64.0 Hereditary sideroblastic anaemia
0.652 0.348 0.000
J36 Peritonsillar abscess
0.652 0.348 0.000
K86.2 Cyst of pancreas
0.651 0.349 0.000
I46 Cardiac arrest
0.651 0.349 0.000
J38.6 Stenosis of larynx
0.650 0.350 0.000
J38.5 Laryngeal spasm
0.650 0.350 0.000
J38.2 Nodules of vocal cords
0.650 0.350 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.647 0.353 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.646 0.354 0.000
S20 Superficial injury of thorax
0.646 0.354 0.000
N20-N23 Urolithiasis
0.646 0.354 0.000
J43 Emphysema
0.646 0.354 0.000
S88 Traumatic amputation of lower leg
0.646 0.354 0.000
S87 Crushing injury of lower leg
0.646 0.354 0.000
S86 Injury of muscle and tendon at lower leg level
0.646 0.354 0.000
S85 Injury of blood vessels at lower leg level
0.646 0.354 0.000
S84 Injury of nerves at lower leg level
0.646 0.354 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.646 0.354 0.000
K51 Ulcerative colitis
0.646 0.354 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.645 0.355 0.000
N30-N39 Other diseases of urinary system
0.645 0.355 0.000
G20-G26 Extrapyramidal and movement disorders
0.645 0.355 0.000
N80.8 Other endometriosis
0.645 0.355 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.644 0.356 0.000
K86.1 Other chronic pancreatitis
0.644 0.356 0.000
S68 Traumatic amputation of wrist and hand
0.643 0.357 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.643 0.357 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.642 0.358 0.000
D74 Methaemoglobinaemia
0.642 0.358 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.642 0.358 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.642 0.358 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.642 0.358 0.000
H35.3 Degeneration of macula and posterior pole
0.642 0.358 0.000
E11 Non-insulin-dependent diabetes mellitus
0.641 0.359 0.000
K86.3 Pseudocyst of pancreas
0.640 0.360 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.640 0.360 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.639 0.361 0.000
S32.0 Fracture of lumbar vertebra
0.639 0.361 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.638 0.362 0.000
S81.8 Open wound of other parts of lower leg
0.638 0.362 0.000
I15 Secondary hypertension
0.637 0.363 0.000
I13 Hypertensive heart and renal disease
0.637 0.363 0.000
K40 Inguinal hernia
0.637 0.363 0.000
N18.5 Chronic kidney disease, stage 5
0.637 0.363 0.000
K02 Dental caries
0.637 0.363 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.637 0.363 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.636 0.364 0.000
N95.3 States associated with artificial menopause
0.636 0.364 0.000
K46 Unspecified abdominal hernia
0.635 0.365 0.000
N94.5 Secondary dysmenorrhoea
0.635 0.365 0.000
N94.4 Primary dysmenorrhoea
0.635 0.365 0.000
N94.3 Premenstrual tension syndrome
0.635 0.365 0.000
N94.2 Vaginismus
0.635 0.365 0.000
N94.0 Mittelschmerz
0.635 0.365 0.000
I35.0 Aortic (valve) stenosis
0.634 0.366 0.000
K29 Gastritis and duodenitis
0.634 0.366 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.631 0.369 0.000
G40-G47 Episodic and paroxysmal disorders
0.631 0.369 0.000
J98.1 Pulmonary collapse
0.630 0.370 0.000
I51.8 Other ill-defined heart diseases
0.629 0.371 0.000
N18.9 Chronic renal failure, unspecified
0.629 0.371 0.000
K63 Other diseases of intestine
0.628 0.372 0.000
K26 Duodenal ulcer
0.627 0.373 0.000
N73 Other female pelvic inflammatory diseases
0.625 0.375 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.625 0.375 0.000
I44.3 Other and unspecified atrioventricular block
0.625 0.375 0.000
D69 Purpura and other haemorrhagic conditions
0.624 0.376 0.000
J30 Vasomotor and allergic rhinitis
0.624 0.376 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.623 0.377 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.623 0.377 0.000
K77 Liver disorders in diseases classified elsewhere
0.622 0.378 0.000
K73 Chronic hepatitis, not elsewhere classified
0.622 0.378 0.000
K71 Toxic liver disease
0.622 0.378 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.622 0.378 0.000
J04 Acute laryngitis and tracheitis
0.622 0.378 0.000
J01 Acute sinusitis
0.622 0.378 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.622 0.378 0.000
I24.8 Other forms of acute ischaemic heart disease
0.622 0.378 0.000
Y35-Y36 Legal intervention and operations of war
0.621 0.379 0.000
Y10-Y34 Event of undetermined intent
0.621 0.379 0.000
Y00-Y09 Assault
0.621 0.379 0.000
X85-X99 Assault
0.621 0.379 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.621 0.379 0.000
X50-X57 Overexertion, travel and privation
0.621 0.379 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.621 0.379 0.000
X30-X39 Exposure to forces of nature
0.621 0.379 0.000
X20-X29 Contact with venomous animals and plants
0.621 0.379 0.000
X10-X19 Contact with heat and hot substances
0.621 0.379 0.000
X00-X09 Exposure to smoke, fire and flames
0.621 0.379 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.621 0.379 0.000
W75-W84 Other accidental threats to breathing
0.621 0.379 0.000
W65-W74 Accidental drowning and submersion
0.621 0.379 0.000
W50-W64 Exposure to animate mechanical forces
0.621 0.379 0.000
V98-V99 Other and unspecified transport accidents
0.621 0.379 0.000
V95-V97 Air and space transport accidents
0.621 0.379 0.000
V90-V94 Water transport accidents
0.621 0.379 0.000
V80-V89 Other land transport accidents
0.621 0.379 0.000
V70-V79 Bus occupant injured in transport accident
0.621 0.379 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.621 0.379 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.621 0.379 0.000
V40-V49 Car occupant injured in transport accident
0.621 0.379 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.621 0.379 0.000
V01-V09 Pedestrian injured in transport accident
0.621 0.379 0.000
J47 Bronchiectasis
0.620 0.380 0.000
S29 Other and unspecified injuries of thorax
0.619 0.381 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.619 0.381 0.000
N06 Isolated proteinuria with specified morphological lesion
0.619 0.381 0.000
N05 Unspecified nephritic syndrome
0.619 0.381 0.000
N04 Nephrotic syndrome
0.619 0.381 0.000
N01 Rapidly progressive nephritic syndrome
0.619 0.381 0.000
N00 Acute nephritic syndrome
0.619 0.381 0.000
Q60-Q64 Congenital malformations of the urinary system
0.618 0.382 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.617 0.382 0.000
N13.6 Pyonephrosis
0.617 0.382 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.617 0.382 0.000
X60-X84 Intentional self-harm
0.617 0.383 0.000
K45 Other abdominal hernia
0.615 0.385 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.614 0.385 0.000
N71 Inflammatory disease of uterus, except cervix
0.614 0.386 0.000
S27 Injury of other and unspecified intrathoracic organs
0.614 0.386 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.614 0.386 0.000
I45 Other conduction disorders
0.614 0.386 0.000
U80 Agent resistant to penicillin and related antibiotics
0.613 0.387 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.613 0.387 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.613 0.387 0.000
H27 Other disorders of lens
0.612 0.388 0.000
K74 Fibrosis and cirrhosis of liver
0.612 0.388 0.000
K07 Dentofacial anomalies [including malocclusion]
0.611 0.388 0.000
V20-V29 Motorcycle rider injured in transport accident
0.611 0.389 0.000
G47 Sleep disorders
0.611 0.389 0.000
Q50-Q56 Congenital malformations of genital organs
0.609 0.391 0.000
S83.2 Tear of meniscus, current
0.609 0.391 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.609 0.391 0.000
I27 Other pulmonary heart diseases
0.608 0.392 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.608 0.392 0.000
K41 Femoral hernia
0.607 0.393 0.000
I20.8 Other forms of angina pectoris
0.606 0.393 0.000
K83.8 Other specified diseases of biliary tract
0.606 0.394 0.000
K50.1 Crohn's disease of large intestine
0.606 0.394 0.000
E11.3 With ophthalmic complications
0.606 0.394 0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.606 0.394 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.606 0.394 0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.606 0.394 0.000
J35.2 Hypertrophy of adenoids
0.606 0.394 0.000
W25 Contact with sharp glass
0.604 0.396 0.000
Chapter V Mental and behavioural disorders
0.604 0.396 0.000
D72 Other disorders of white blood cells
0.602 0.398 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.602 0.398 0.000
S82 Fracture of lower leg, including ankle
0.602 0.398 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.601 0.398 0.000
J96 Respiratory failure, not elsewhere classified
0.601 0.398 0.000
K81.8 Other cholecystitis
0.601 0.399 0.000
I74 Arterial embolism and thrombosis
0.601 0.399 0.000
K52 Other non-infective gastro-enteritis and colitis
0.600 0.400 0.000
N03 Chronic nephritic syndrome
0.600 0.400 0.000
N92.6 Irregular menstruation, unspecified
0.599 0.401 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.599 0.401 0.000
S40-S49 Injuries to the shoulder and upper arm
0.599 0.401 0.000
K82.9 Disease of gallbladder, unspecified
0.598 0.402 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.597 0.403 0.000
S37 Injury of urinary and pelvic organs
0.597 0.403 0.000
S36 Injury of intra-abdominal organs
0.597 0.403 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.597 0.403 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.597 0.403 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.597 0.403 0.000
S31 Open wound of abdomen, lower back and pelvis
0.597 0.403 0.000
K81.9 Cholecystitis, unspecified
0.597 0.403 0.000
H53.9 Visual disturbance, unspecified
0.596 0.404 0.000
K29.6 Other gastritis
0.596 0.404 0.000
I24.1 Dressler's syndrome
0.596 0.404 0.000
H35.9 Retinal disorder, unspecified
0.595 0.405 0.000
H35.7 Separation of retinal layers
0.595 0.405 0.000
H35.6 Retinal haemorrhage
0.595 0.405 0.000
H35.4 Peripheral retinal degeneration
0.595 0.405 0.000
H35.2 Other proliferative retinopathy
0.595 0.405 0.000
H35.1 Retinopathy of prematurity
0.595 0.405 0.000
H35.0 Background retinopathy and retinal vascular changes
0.595 0.405 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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