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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35455030
log Bayes Factor = 191.11
Chromosome 6   position 32,522,650  (GRCh37) Explore rs35455030 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
J45 Asthma
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
E10.4 With neurological complications
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.002 0.998
J30-J39 Other diseases of upper respiratory tract
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.002 0.998
E14.9 Without complications
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.003 0.997
H40-H42 Glaucoma
0.000 0.003 0.997
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
H40.9 Glaucoma, unspecified
0.000 0.005 0.995
H40 Glaucoma
0.000 0.005 0.995
H43-H45 Disorders of vitreous body and globe
0.000 0.005 0.995
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.005 0.995
G35-G37 Demyelinating diseases of the central nervous system
0.993 0.006 0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.006 0.994
K51.3 Ulcerative (chronic) rectosigmoiditis
0.994 0.006 0.000
H43 Disorders of vitreous body
0.000 0.007 0.993
E14.3 With ophthalmic complications
0.000 0.007 0.993
G37 Other demyelinating diseases of central nervous system
0.992 0.008 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.010 0.990
J33.8 Other polyp of sinus
0.000 0.010 0.990
G37.9 Demyelinating disease of central nervous system, unspecified
0.989 0.011 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.012 0.988
K70-K77 Diseases of liver
0.000 0.015 0.985
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.018 0.982
E11.3 With ophthalmic complications
0.000 0.020 0.980
E70-E90 Metabolic disorders
0.000 0.021 0.979
H43.8 Other disorders of vitreous body
0.000 0.026 0.974
L40-L45 Papulosquamous disorders
0.000 0.026 0.974
I20-I25 Ischaemic heart diseases
0.000 0.026 0.974
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.026 0.974
K51.8 Other ulcerative colitis
0.973 0.027 0.000
Chapter IX Diseases of the circulatory system
0.000 0.027 0.973
L40 Psoriasis
0.000 0.028 0.972
L43 Lichen planus
0.000 0.030 0.970
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.033 0.967
K74 Fibrosis and cirrhosis of liver
0.000 0.033 0.967
E10.5 With peripheral circulatory complications
0.000 0.034 0.966
L43.9 Lichen planus, unspecified
0.000 0.035 0.965
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.035 0.965
H43.3 Other vitreous opacities
0.000 0.036 0.964
K82 Other diseases of gallbladder
0.000 0.036 0.964
L40.5 Arthropathic psoriasis
0.000 0.036 0.964
I20 Angina pectoris
0.000 0.037 0.963
K82.8 Other specified diseases of gallbladder
0.000 0.038 0.962
I22 Subsequent myocardial infarction
0.000 0.038 0.962
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.042 0.958
J33.0 Polyp of nasal cavity
0.000 0.044 0.956
I10-I15 Hypertensive diseases
0.000 0.052 0.948
J44 Other chronic obstructive pulmonary disease
0.000 0.052 0.948
E06 Thyroiditis
0.000 0.057 0.943
K74.3 Primary biliary cirrhosis
0.000 0.057 0.943
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.059 0.941
E11.1 With ketoacidosis
0.000 0.059 0.941
E10.2 With renal complications
0.000 0.061 0.939
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.063 0.937
J46 Status asthmaticus
0.000 0.063 0.937
K50-K52 Noninfective enteritis and colitis
0.017 0.065 0.918
K51.2 Ulcerative (chronic) proctitis
0.927 0.073 0.000
J32 Chronic sinusitis
0.000 0.077 0.923
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.078 0.922
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.081 0.919
H34 Retinal vascular occlusions
0.000 0.086 0.914
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.089 0.911
L40.9 Psoriasis, unspecified
0.000 0.090 0.910
I20.0 Unstable angina
0.000 0.093 0.907
I20.1 Angina pectoris with documented spasm
0.000 0.093 0.907
E11.5 With peripheral circulatory complications
0.000 0.093 0.907
E06.3 Autoimmune thyroiditis
0.000 0.094 0.906
I20.9 Angina pectoris, unspecified
0.000 0.094 0.906
K72 Hepatic failure, not elsewhere classified
0.000 0.094 0.906
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.096 0.904
E11.2 With renal complications
0.000 0.102 0.898
J43 Emphysema
0.000 0.108 0.892
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.108 0.892
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.116 0.884
E11.6 With other specified complications
0.000 0.118 0.882
E13 Other specified diabetes mellitus
0.000 0.118 0.882
M06.0 Seronegative rheumatoid arthritis
0.000 0.121 0.879
M65-M68 Disorders of synovium and tendon
0.000 0.123 0.877
J86 Pyothorax
0.000 0.124 0.876
H25-H28 Disorders of lens
0.000 0.126 0.874
M07 Psoriatic and enteropathic arthropathies
0.000 0.129 0.871
J32.9 Chronic sinusitis, unspecified
0.000 0.132 0.868
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.135 0.865
E03.8 Other specified hypothyroidism
0.000 0.137 0.863
I12 Hypertensive renal disease
0.000 0.140 0.860
H40.5 Glaucoma secondary to other eye disorders
0.000 0.155 0.845
J86.9 Pyothorax without fistula
0.000 0.157 0.843
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.834 0.166 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.168 0.832
I10 Essential (primary) hypertension
0.000 0.168 0.832
M70-M79 Other soft tissue disorders
0.000 0.173 0.827
K51.4 Pseudopolyposis of colon
0.827 0.173 0.000
K82.1 Hydrops of gallbladder
0.000 0.178 0.822
G37.8 Other specified demyelinating diseases of central nervous system
0.820 0.180 0.000
K74.5 Biliary cirrhosis, unspecified
0.000 0.183 0.817
H40.1 Primary open-angle glaucoma
0.000 0.184 0.816
K51.5 Mucosal proctocolitis
0.812 0.188 0.000
K50 Crohn's disease [regional enteritis]
0.001 0.188 0.811
K52 Other non-infective gastro-enteritis and colitis
0.003 0.189 0.808
E88 Other metabolic disorders
0.000 0.198 0.801
E78.2 Mixed hyperlipidaemia
0.000 0.199 0.801
K86 Other diseases of pancreas
0.000 0.203 0.797
E13.9 Without complications
0.000 0.203 0.797
M06.3 Rheumatoid nodule
0.000 0.203 0.797
E07 Other disorders of thyroid
0.000 0.205 0.795
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.205 0.795
H25 Senile cataract
0.000 0.206 0.794
K75 Other inflammatory liver diseases
0.000 0.206 0.794
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.207 0.793
M65 Synovitis and tenosynovitis
0.000 0.209 0.791
H25.1 Senile nuclear cataract
0.000 0.209 0.791
K72.9 Hepatic failure, unspecified
0.000 0.210 0.790
I15 Secondary hypertension
0.000 0.210 0.790
I24 Other acute ischaemic heart diseases
0.000 0.210 0.790
J43.9 Emphysema, unspecified
0.000 0.212 0.788
H27 Other disorders of lens
0.000 0.213 0.786
M06.4 Inflammatory polyarthropathy
0.000 0.216 0.783
K73 Chronic hepatitis, not elsewhere classified
0.000 0.217 0.783
K90.9 Intestinal malabsorption, unspecified
0.000 0.219 0.781
K72.0 Acute and subacute hepatic failure
0.000 0.219 0.781
M07.3 Other psoriatic arthropathies
0.000 0.221 0.779
L43.8 Other lichen planus
0.000 0.221 0.778
K81 Cholecystitis
0.000 0.222 0.778
K74.6 Other and unspecified cirrhosis of liver
0.000 0.224 0.776
H34.8 Other retinal vascular occlusions
0.000 0.225 0.775
M14 Arthropathies in other diseases classified elsewhere
0.000 0.227 0.773
M75 Shoulder lesions
0.000 0.231 0.769
I12.9 Hypertensive renal disease without renal failure
0.000 0.235 0.765
E11.0 With coma
0.000 0.236 0.764
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.237 0.763
H43.1 Vitreous haemorrhage
0.000 0.237 0.763
J32.4 Chronic pansinusitis
0.000 0.238 0.762
K51.0 Ulcerative (chronic) enterocolitis
0.761 0.239 0.000
E40-E46 Malnutrition
0.000 0.240 0.760
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.241 0.759
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.241 0.759
H34.1 Central retinal artery occlusion
0.000 0.246 0.754
E78.1 Pure hyperglyceridaemia
0.000 0.247 0.753
M75.0 Adhesive capsulitis of shoulder
0.000 0.247 0.753
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.247 0.753
H43.2 Crystalline deposits in vitreous body
0.000 0.251 0.749
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.253 0.747
K75.4 Autoimmune hepatitis
0.000 0.255 0.745
H30 Chorioretinal inflammation
0.000 0.257 0.743
I11 Hypertensive heart disease
0.000 0.260 0.740
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.267 0.733
H43.9 Disorder of vitreous body, unspecified
0.000 0.268 0.732
H34.2 Other retinal artery occlusions
0.000 0.270 0.730
J37 Chronic laryngitis and laryngotracheitis
0.000 0.271 0.729
E74 Other disorders of carbohydrate metabolism
0.000 0.273 0.727
M77 Other enthesopathies
0.000 0.273 0.727
Chapter VIII Diseases of the ear and mastoid process
0.000 0.274 0.726
L40.0 Psoriasis vulgaris
0.000 0.278 0.722
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.279 0.721
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E16.1 Other hypoglycaemia
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.285 0.715
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.285 0.715
K90.1 Tropical sprue
0.000 0.285 0.715
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.285 0.715
H42 Glaucoma in diseases classified elsewhere
0.000 0.285 0.715
E11.8 With unspecified complications
0.000 0.286 0.714
I23 Certain current complications following acute myocardial infarction
0.000 0.286 0.714
H40.6 Glaucoma secondary to drugs
0.000 0.287 0.713
H40.4 Glaucoma secondary to eye inflammation
0.000 0.287 0.713
H40.3 Glaucoma secondary to eye trauma
0.000 0.287 0.713
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.287 0.713
G36 Other acute disseminated demyelination
0.712 0.287 0.001
H43.0 Vitreous prolapse
0.000 0.288 0.712
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.288 0.712
G37.5 Concentric sclerosis [Balo]
0.711 0.288 0.000
G37.4 Subacute necrotising myelitis
0.711 0.288 0.000
G37.2 Central pontine myelinolysis
0.711 0.288 0.000
G37.1 Central demyelination of corpus callosum
0.711 0.288 0.000
G37.0 Diffuse sclerosis
0.711 0.288 0.000
K52.1 Toxic gastro-enteritis and colitis
0.001 0.290 0.709
K50.1 Crohn's disease of large intestine
0.000 0.290 0.709
M12 Other specific arthropathies
0.000 0.291 0.709
K81.1 Chronic cholecystitis
0.000 0.292 0.708
M77.1 Lateral epicondylitis
0.000 0.293 0.707
K77 Liver disorders in diseases classified elsewhere
0.000 0.294 0.706
K71 Toxic liver disease
0.000 0.294 0.706
J43.2 Centrilobular emphysema
0.000 0.294 0.706
M20-M25 Other joint disorders
0.000 0.295 0.705
E78.6 Lipoprotein deficiency
0.000 0.296 0.704
E78.3 Hyperchylomicronaemia
0.000 0.296 0.704
L40.8 Other psoriasis
0.000 0.296 0.704
M11 Other crystal arthropathies
0.000 0.296 0.704
E77 Disorders of glycoprotein metabolism
0.000 0.298 0.702
E76 Disorders of glycosaminoglycan metabolism
0.000 0.298 0.702
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.298 0.702
E72 Other disorders of amino-acid metabolism
0.000 0.298 0.702
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.298 0.702
E70 Disorders of aromatic amino-acid metabolism
0.000 0.298 0.702
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.298 0.702
K82.9 Disease of gallbladder, unspecified
0.000 0.299 0.701
K82.3 Fistula of gallbladder
0.000 0.299 0.701
K50.8 Other Crohn's disease
0.000 0.301 0.699
I12.0 Hypertensive renal disease with renal failure
0.000 0.301 0.699
L44 Other papulosquamous disorders
0.000 0.301 0.698
L41 Parapsoriasis
0.000 0.301 0.698
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.301 0.698
K82.2 Perforation of gallbladder
0.000 0.302 0.698
I00-I02 Acute rheumatic fever
0.000 0.302 0.697
H60-H62 Diseases of external ear
0.000 0.303 0.697
L40.4 Guttate psoriasis
0.000 0.303 0.697
L40.3 Pustulosis palmaris et plantaris
0.000 0.303 0.697
L40.2 Acrodermatitis continua
0.000 0.303 0.697
L40.1 Generalised pustular psoriasis
0.000 0.303 0.697
M35.3 Polymyalgia rheumatica
0.000 0.303 0.697
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.303 0.697
L43.3 Subacute (active) lichen planus
0.000 0.305 0.695
L43.2 Lichenoid drug reaction
0.000 0.305 0.695
L43.1 Bullous lichen planus
0.000 0.305 0.695
L43.0 Hypertrophic lichen planus
0.000 0.305 0.695
E11.4 With neurological complications
0.000 0.305 0.695
J41 Simple and mucopurulent chronic bronchitis
0.000 0.305 0.694
M35 Other systemic involvement of connective tissue
0.000 0.306 0.694
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.306 0.694
K74.4 Secondary biliary cirrhosis
0.000 0.307 0.693
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.307 0.693
K74.1 Hepatic sclerosis
0.000 0.307 0.693
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.307 0.693
E78.5 Hyperlipidaemia, unspecified
0.000 0.308 0.692
E07.9 Disorder of thyroid, unspecified
0.000 0.316 0.684
I13 Hypertensive heart and renal disease
0.000 0.320 0.680
E83 Disorders of mineral metabolism
0.566 0.321 0.113
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.322 0.678
E06.5 Other chronic thyroiditis
0.000 0.324 0.676
E06.4 Drug-induced thyroiditis
0.000 0.324 0.676
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.324 0.676
E06.1 Subacute thyroiditis
0.000 0.324 0.676
E06.0 Acute thyroiditis
0.000 0.324 0.676
H61 Other disorders of external ear
0.000 0.327 0.673
K86.2 Cyst of pancreas
0.000 0.327 0.673
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.329 0.671
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.331 0.669
H27.8 Other specified disorders of lens
0.000 0.332 0.668
K82.0 Obstruction of gallbladder
0.000 0.333 0.667
K52.8 Other specified non-infective gastro-enteritis and colitis
0.001 0.334 0.666
M66 Spontaneous rupture of synovium and tendon
0.000 0.334 0.665
M14.6 Neuropathic arthropathy
0.000 0.339 0.661
M75.2 Bicipital tendinitis
0.000 0.342 0.658
E79 Disorders of purine and pyrimidine metabolism
0.000 0.344 0.656
H34.9 Retinal vascular occlusion, unspecified
0.000 0.344 0.656
H34.0 Transient retinal artery occlusion
0.000 0.344 0.656
M72 Fibroblastic disorders
0.000 0.345 0.655
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.346 0.654
H27.0 Aphakia
0.000 0.346 0.654
J32.1 Chronic frontal sinusitis
0.000 0.347 0.653
E84 Cystic fibrosis
0.000 0.347 0.652
I15.1 Hypertension secondary to other renal disorders
0.000 0.347 0.653
H33 Retinal detachments and breaks
0.000 0.350 0.650
K72.1 Chronic hepatic failure
0.000 0.350 0.649
E06.9 Thyroiditis, unspecified
0.000 0.353 0.647
K81.9 Cholecystitis, unspecified
0.000 0.353 0.647
I25 Chronic ischaemic heart disease
0.000 0.355 0.645
J32.8 Other chronic sinusitis
0.000 0.357 0.643
J32.2 Chronic ethmoidal sinusitis
0.000 0.357 0.643
H61.0 Perichondritis of external ear
0.000 0.359 0.641
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.359 0.640
J43.8 Other emphysema
0.000 0.360 0.640
J43.1 Panlobular emphysema
0.000 0.360 0.640
J43.0 MacLeod's syndrome
0.000 0.360 0.640
E05.5 Thyroid crisis or storm
0.000 0.361 0.639
E05.4 Thyrotoxicosis factitia
0.000 0.361 0.639
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.361 0.639
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.361 0.639
M10 Gout
0.000 0.361 0.639
K86.8 Other specified diseases of pancreas
0.000 0.362 0.638
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.365 0.634
J60-J70 Lung diseases due to external agents
0.000 0.367 0.633
E13.8 With unspecified complications
0.000 0.368 0.632
E13.7 With multiple complications
0.000 0.368 0.632
E13.6 With other specified complications
0.000 0.368 0.632
E13.5 With peripheral circulatory complications
0.000 0.368 0.632
E13.4 With neurological complications
0.000 0.368 0.632
E13.3 With ophthalmic complications
0.000 0.368 0.632
E13.2 With renal complications
0.000 0.368 0.632
E13.1 With ketoacidosis
0.000 0.368 0.632
E13.0 With coma
0.000 0.368 0.632
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.368 0.631
K86.3 Pseudocyst of pancreas
0.000 0.369 0.631
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.370 0.630
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.370 0.630
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.370 0.630
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.370 0.630
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.370 0.630
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.370 0.630
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.370 0.630
M34 Systemic sclerosis
0.000 0.371 0.629
K86.1 Other chronic pancreatitis
0.000 0.371 0.629
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.371 0.629
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.372 0.628
J86.0 Pyothorax with fistula
0.000 0.372 0.628
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.373 0.627
M45-M49 Spondylopathies
0.000 0.374 0.626
M07.6 Other enteropathic arthropathies
0.000 0.375 0.624
M07.5 Arthropathy in ulcerative colitis
0.000 0.375 0.624
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.375 0.624
M07.2 Psoriatic spondylitis
0.000 0.375 0.624
M07.1 Arthritis mutilans
0.000 0.375 0.624
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.375 0.624
J32.0 Chronic maxillary sinusitis
0.000 0.376 0.624
J32.3 Chronic sphenoidal sinusitis
0.000 0.378 0.622
L42 Pityriasis rosea
0.000 0.379 0.621
K73.9 Chronic hepatitis, unspecified
0.000 0.382 0.617
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.384 0.616
M06.34 Rheumatoid nodule (Hand)
0.000 0.385 0.615
K50.0 Crohn's disease of small intestine
0.000 0.387 0.612
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.389 0.610
J85 Abscess of lung and mediastinum
0.000 0.390 0.610
M65.1 Other infective (teno)synovitis
0.000 0.391 0.609
J31.2 Chronic pharyngitis
0.000 0.391 0.608
L10-L14 Bullous disorders
0.000 0.393 0.607
E88.2 Lipomatosis, not elsewhere classified
0.000 0.394 0.606
I22.8 Subsequent myocardial infarction of other sites
0.000 0.394 0.606
I15.9 Seconday hypertension, unspecified
0.000 0.395 0.604
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.397 0.603
M45 Ankylosing spondylitis
0.000 0.400 0.600
K90.8 Other intestinal malabsorption
0.000 0.400 0.600
H35 Other retinal disorders
0.000 0.401 0.599
M60-M63 Disorders of muscles
0.000 0.403 0.597
M75.3 Calcific tendinitis of shoulder
0.000 0.403 0.597
K74.0 Hepatic fibrosis
0.000 0.405 0.595
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.407 0.593
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.408 0.592
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.409 0.591
M67 Other disorders of synovium and tendon
0.000 0.410 0.590
H33.0 Retinal detachment with retinal break
0.000 0.410 0.590
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.411 0.589
H27.1 Dislocation of lens
0.000 0.412 0.588
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.412 0.588
E46 Unspecified protein-energy malnutrition
0.000 0.413 0.587
E05.8 Other thyrotoxicosis
0.000 0.414 0.586
H61.8 Other specified disorders of external ear
0.000 0.414 0.586
E78.8 Other disorders of lipoprotein metabolism
0.000 0.416 0.584
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.416 0.584
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.416 0.584
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.000 0.417 0.583
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.419 0.581
I25.5 Ischaemic cardiomyopathy
0.000 0.421 0.579
M00-M03 Infectious arthropathies
0.000 0.421 0.579
E88.9 Metabolic disorder, unspecified
0.000 0.425 0.575
E88.8 Other specified metabolic disorders
0.000 0.425 0.575
E88.3 Tumour lysis syndrome
0.000 0.425 0.575
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.425 0.575
M24 Other specific joint derangements
0.000 0.426 0.574
J95-J99 Other diseases of the respiratory system
0.000 0.429 0.571
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.429 0.571
M06.38 Rheumatoid nodule (Other)
0.000 0.429 0.571
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.429 0.571
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.429 0.571
M06.33 Rheumatoid nodule (Forearm)
0.000 0.429 0.571
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.429 0.571
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.429 0.571
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.429 0.571
E07.1 Dyshormogenetic goitre
0.000 0.430 0.570
E07.0 Hypersecretion of calcitonin
0.000 0.430 0.570
H25.2 Senile cataract, morgagnian type
0.000 0.430 0.570
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.430 0.569
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.431 0.569
K75.2 Nonspecific reactive hepatitis
0.000 0.431 0.569
K75.1 Phlebitis of portal vein
0.000 0.431 0.569
I21 Acute myocardial infarction
0.000 0.432 0.568
M65.2 Calcific tendinitis
0.000 0.433 0.567
M65.0 Abscess of tendon sheath
0.000 0.433 0.567
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.002 0.433 0.565
I15.8 Other secondary hypertension
0.000 0.434 0.566
I15.2 Hypertension secondary to endocrine disorders
0.000 0.434 0.566
I15.0 Renovascular hypertension
0.000 0.434 0.566
M35.7 Hypermobility syndrome
0.000 0.436 0.564
H27.9 Disorder of lens, unspecified
0.000 0.436 0.564
M15-M19 Arthrosis
0.000 0.436 0.564
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.438 0.562
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.438 0.562
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.438 0.562
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.438 0.562
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.438 0.562
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.438 0.562
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.438 0.562
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.438 0.562
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.438 0.562
E85 Amyloidosis
0.000 0.438 0.561
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.439 0.561
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.439 0.561
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.439 0.561
J42 Unspecified chronic bronchitis
0.000 0.439 0.561
H30.9 Chorioretinal inflammation, unspecified
0.000 0.440 0.559
M07.38 Other psoriatic arthropathies (Other)
0.000 0.442 0.558
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.442 0.558
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.442 0.558
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.442 0.558
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.442 0.558
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.442 0.558
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.442 0.558
J35 Chronic diseases of tonsils and adenoids
0.000 0.443 0.557
E73 Lactose intolerance
0.001 0.445 0.554
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.446 0.554
M14.4 Arthropathy in amyloidosis
0.000 0.446 0.554
M14.3 Lipoid dermatoarthritis
0.000 0.446 0.554
M14.2 Diabetic arthropathy
0.000 0.446 0.554
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.446 0.554
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.446 0.554
K81.8 Other cholecystitis
0.000 0.446 0.553
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.447 0.552
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.001 0.448 0.551
M75.8 Other shoulder lesions
0.000 0.449 0.551
K75.9 Inflammatory liver disease, unspecified
0.000 0.450 0.550
J31.0 Chronic rhinitis
0.000 0.451 0.549

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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