TreeWAS – Variant ID: rs35473622

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.000	1.000
I10-I15 Hypertensive diseases	0.000	0.816	0.184
I13 Hypertensive heart and renal disease	0.000	0.868	0.132
I11 Hypertensive heart disease	0.000	0.888	0.112
I15 Secondary hypertension	0.000	0.890	0.110
I12 Hypertensive renal disease	0.000	0.900	0.099
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.905	0.095
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.905	0.095
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.905	0.095
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.905	0.095
I15.8 Other secondary hypertension	0.000	0.921	0.079
I15.2 Hypertension secondary to endocrine disorders	0.000	0.921	0.079
I15.0 Renovascular hypertension	0.000	0.922	0.077
I12.9 Hypertensive renal disease without renal failure	0.000	0.924	0.076
I15.1 Hypertension secondary to other renal disorders	0.000	0.924	0.075
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.925	0.075
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.933	0.066
I15.9 Seconday hypertension, unspecified	0.000	0.936	0.064
I12.0 Hypertensive renal disease with renal failure	0.000	0.972	0.028
S09.9 Unspecified injury of head	0.000	0.979	0.021
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.982	0.018
S05 Injury of eye and orbit	0.000	0.986	0.014
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.986	0.014
S05.1 Contusion of eyeball and orbital tissues	0.000	0.986	0.013
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.013	0.987	0.000
S09 Other and unspecified injuries of head	0.000	0.987	0.013
S09.0 Injury of blood vessels of head, not elsewhere classified	0.000	0.989	0.011
S05.9 Injury of eye and orbit, part unspecified	0.000	0.989	0.011
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.989	0.011
S05.8 Other injuries of eye and orbit	0.000	0.990	0.010
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.990	0.010
S05.7 Avulsion of eye	0.000	0.990	0.010
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.990	0.010
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.990	0.010
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.990	0.010
S09.7 Multiple injuries of head	0.000	0.990	0.010
S09.2 Traumatic rupture of ear drum	0.000	0.990	0.010
S09.1 Injury of muscle and tendon of head	0.000	0.990	0.010
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.009	0.991	0.000
G56.2 Lesion of ulnar nerve	0.009	0.991	0.000
K83.0 Cholangitis	0.009	0.991	0.000
C79 Secondary malignant neoplasm of other sites	0.009	0.991	0.000
C79.6 Secondary malignant neoplasm of ovary	0.009	0.991	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.009	0.991	0.000
K83.1 Obstruction of bile duct	0.009	0.991	0.000
S09.8 Other specified injuries of head	0.000	0.992	0.008
K83 Other diseases of biliary tract	0.008	0.992	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.993	0.007
S01.3 Open wound of ear	0.007	0.993	0.000
K83.8 Other specified diseases of biliary tract	0.007	0.993	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.993	0.007
C79.2 Secondary malignant neoplasm of skin	0.007	0.993	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.007	0.993	0.000
C78.0 Secondary malignant neoplasm of lung	0.007	0.993	0.000
T93 Sequelae of injuries of lower limb	0.006	0.994	0.000
S00-S09 Injuries to the head	0.000	0.994	0.006
C78.7 Secondary malignant neoplasm of liver	0.006	0.994	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.006	0.994	0.000
K83.5 Biliary cyst	0.006	0.994	0.000
K83.3 Fistula of bile duct	0.006	0.994	0.000
K83.2 Perforation of bile duct	0.006	0.994	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.006	0.994	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.994	0.006
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.006	0.994	0.000
K83.9 Disease of biliary tract, unspecified	0.006	0.994	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.994	0.006
K83.4 Spasm of sphincter of Oddi	0.006	0.994	0.000
T93.0 Sequelae of open wound of lower limb	0.006	0.994	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.005	0.994	0.000
T93.2 Sequelae of other fractures of lower limb	0.006	0.994	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.005	0.995	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.005	0.995	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.000	0.995	0.005
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.005	0.995	0.000
I78.1 Naevus, nonneoplastic	0.000	0.995	0.005
M24.1 Other articular cartilage disorders	0.005	0.995	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.005	0.995	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.005	0.995	0.000
N82.3 Fistula of vagina to large intestine	0.005	0.995	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.005	0.995	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.005	0.995	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.005	0.995	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.005	0.995	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.005	0.995	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.005	0.995	0.000
S08 Traumatic amputation of part of head	0.000	0.995	0.005
S07 Crushing injury of head	0.000	0.995	0.005
S04 Injury of cranial nerves	0.000	0.995	0.005
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.005	0.995	0.000
T93.1 Sequelae of fracture of femur	0.005	0.995	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.005	0.995	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.005	0.995	0.000
S03.2 Dislocation of tooth	0.000	0.995	0.005
I78 Diseases of capillaries	0.000	0.995	0.005
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.995	0.005
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.004	0.995	0.000
C80 Malignant neoplasm without specification of site	0.004	0.996	0.000
M24 Other specific joint derangements	0.004	0.996	0.000
M24.2 Disorder of ligament	0.004	0.996	0.000
M24.24 Disorder of ligament (Hand)	0.004	0.996	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.004	0.996	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.000	0.996	0.004
S03.4 Sprain and strain of jaw	0.000	0.996	0.004
S03.3 Dislocation of other and unspecified parts of head	0.000	0.996	0.004
S03.1 Dislocation of septal cartilage of nose	0.000	0.996	0.004
S03.0 Dislocation of jaw	0.000	0.996	0.004
C79.7 Secondary malignant neoplasm of adrenal gland	0.004	0.996	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.004	0.996	0.000
M24.18 Other articular cartilage disorders (Other)	0.004	0.996	0.000
M24.14 Other articular cartilage disorders (Hand)	0.004	0.996	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.004	0.996	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.004	0.996	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.004	0.996	0.000
M24.6 Ankylosis of joint	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.996	0.004
S67.0 Crushing injury of thumb and other finger(s)	0.004	0.996	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.004	0.996	0.000
S04.9 Injury of unspecified cranial nerve	0.000	0.996	0.004
S04.8 Injury of other cranial nerves	0.000	0.996	0.004
S04.7 Injury of accessory nerve	0.000	0.996	0.004
S04.6 Injury of acoustic nerve	0.000	0.996	0.004
S04.5 Injury of facial nerve	0.000	0.996	0.004
S04.4 Injury of abducent nerve	0.000	0.996	0.004
S04.3 Injury of trigeminal nerve	0.000	0.996	0.004
S04.2 Injury of trochlear nerve	0.000	0.996	0.004
S04.1 Injury of oculomotor nerve	0.000	0.996	0.004
S04.0 Injury of optic nerve and pathways	0.000	0.996	0.004
S07.9 Crushing injury of head, part unspecified	0.000	0.996	0.004
S07.8 Crushing injury of other parts of head	0.000	0.996	0.004
S07.1 Crushing injury of skull	0.000	0.996	0.004
S07.0 Crushing injury of face	0.000	0.996	0.004
S08.9 Traumatic amputation of unspecified part of head	0.000	0.996	0.004
S08.8 Traumatic amputation of other parts of head	0.000	0.996	0.004
S08.1 Traumatic amputation of ear	0.000	0.996	0.004
S08.0 Avulsion of scalp	0.000	0.996	0.004
M24.27 Disorder of ligament (Ankle and foot)	0.004	0.996	0.000
M24.66 Ankylosis of joint (Lower leg)	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
S00.3 Superficial injury of nose	0.000	0.996	0.004
Q51.3 Bicornate uterus	0.004	0.996	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.996	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.996	0.003
I78.8 Other diseases of capillaries	0.000	0.996	0.003
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.003	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.003	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.003	0.996	0.000
M24.28 Disorder of ligament (Other)	0.003	0.996	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.997	0.003
Z95.4 Presence of other heart-valve replacement	0.000	0.997	0.003
M24.9 Joint derangement, unspecified	0.003	0.997	0.000
D11.0 Parotid gland	0.003	0.997	0.000
C76.3 Pelvis	0.003	0.997	0.000
M24.29 Disorder of ligament (Site unspecified)	0.003	0.997	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.003	0.997	0.000
M24.22 Disorder of ligament (Upper arm)	0.003	0.997	0.000
M24.20 Disorder of ligament (Multiple sites)	0.003	0.997	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.003	0.997	0.000
M24.7 Protrusio acetabuli	0.003	0.997	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.003	0.997	0.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.997	0.003
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.997	0.003
M24.26 Disorder of ligament (Lower leg)	0.003	0.997	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.003	0.997	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.003	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.003	0.997	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.997	0.003
Y42.5 Other oestrogens and progestogens	0.000	0.997	0.003
S00 Superficial injury of head	0.000	0.997	0.003
C76.8 Overlapping lesion of other and ill-defined sites	0.003	0.997	0.000
C76.7 Other ill-defined sites	0.003	0.997	0.000
C76.5 Lower limb	0.003	0.997	0.000
C76.4 Upper limb	0.003	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.003	0.997	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.003
I74 Arterial embolism and thrombosis	0.000	0.997	0.003
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
H35.7 Separation of retinal layers	0.003	0.997	0.000
C76.0 Head, face and neck	0.003	0.997	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.003	0.997	0.000
M24.64 Ankylosis of joint (Hand)	0.003	0.997	0.000
I70.0 Atherosclerosis of aorta	0.000	0.997	0.003
C76.2 Abdomen	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.003	0.997	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.003	0.997	0.000
C78.2 Secondary malignant neoplasm of pleura	0.003	0.997	0.000
C76.1 Thorax	0.003	0.997	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.003	0.997	0.000
M24.21 Disorder of ligament (Shoulder region)	0.003	0.997	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.997	0.003
M24.4 Recurrent dislocation and subluxation of joint	0.003	0.997	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.997	0.003
N30.1 Interstitial cystitis (chronic)	0.003	0.997	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.997	0.003
M24.5 Contracture of joint	0.003	0.997	0.000
F32.1 Moderate depressive episode	0.003	0.997	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.997	0.003
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.997	0.003
M24.99 Joint derangement, unspecified (Site unspecified)	0.002	0.997	0.000
M24.98 Joint derangement, unspecified (Other)	0.002	0.997	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.002	0.997	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.002	0.997	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.002	0.997	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.997	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.002	0.997	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.002	0.997	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.002	0.997	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.002	0.997	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.997	0.003
M24.0 Loose body in joint	0.003	0.997	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.997	0.000
Z04.3 Examination and observation following other accident	0.003	0.997	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
I70 Atherosclerosis	0.000	0.997	0.003
Chapter IX Diseases of the circulatory system	0.000	0.997	0.003
M24.79 Protrusio acetabuli-Site unspec	0.002	0.997	0.000
M24.78 Protrusio acetabuli-Other	0.002	0.997	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.002	0.997	0.000
M24.76 Protrusio acetabuli-Lower leg	0.002	0.997	0.000
M24.74 Protrusio acetabuli-Hand	0.002	0.997	0.000
M24.73 Protrusio acetabuli-Forearm	0.002	0.997	0.000
M24.72 Protrusio acetabuli-Upper arm	0.002	0.997	0.000
M24.71 Protrusio acetabuli-Shldr region	0.002	0.997	0.000
M24.70 Protrusio acetabuli-Mult sites	0.002	0.997	0.000
S00.4 Superficial injury of ear	0.000	0.997	0.003
C25.2 Tail of pancreas	0.003	0.997	0.000
G71.0 Muscular dystrophy	0.003	0.997	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.997	0.002
I74.8 Embolism and thrombosis of other arteries	0.000	0.997	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.997	0.002
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.997	0.000
H47.1 Papilloedema, unspecified	0.000	0.997	0.002
Z11.1 Special screening examination for respiratory tuberculosis	0.000	0.997	0.002
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.997	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.998	0.002
G56.1 Other lesions of median nerve	0.002	0.998	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
S00.0 Superficial injury of scalp	0.000	0.998	0.002
G56 Mononeuropathies of upper limb	0.002	0.998	0.000
C62.9 Testis, unspecified	0.002	0.998	0.000
G72.9 Myopathy, unspecified	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.002	0.998	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.998	0.000
H46 Optic neuritis	0.000	0.998	0.002
N82 Fistulae involving female genital tract	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.998	0.002
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.002	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.002	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.002	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.002	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.002	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.002	0.998	0.000
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
Z11.8 Special screening examination for other infectious and parasitic diseases	0.000	0.998	0.002
N82.0 Vesicovaginal fistula	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.002	0.998	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.000	0.998	0.002
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.000	0.998	0.002
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.998	0.002
S00.5 Superficial injury of lip and oral cavity	0.000	0.998	0.002
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.000	0.998	0.002
G72 Other myopathies	0.002	0.998	0.000
I63 Cerebral infarction	0.000	0.998	0.002
I62 Other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
C25 Malignant neoplasm of pancreas	0.002	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
M24.09 Loose body in joint (Site unspecified)	0.002	0.998	0.000
M24.08 Loose body in joint (Other)	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.00 Loose body in joint (Multiple sites)	0.002	0.998	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
I00-I02 Acute rheumatic fever	0.000	0.998	0.002
M24.04 Loose body in joint (Hand)	0.002	0.998	0.000
C25.9 Pancreas, unspecified	0.002	0.998	0.000
C25.1 Body of pancreas	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.998	0.002
I70.9 Generalised and unspecified atherosclerosis	0.000	0.998	0.002
G52 Disorders of other cranial nerves	0.002	0.998	0.000
I60-I69 Cerebrovascular diseases	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
G72.8 Other specified myopathies	0.002	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
G72.0 Drug-induced myopathy	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.998	0.002
G52.9 Cranial nerve disorder, unspecified	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
G52.3 Disorders of hypoglossal nerve	0.002	0.998	0.000
I70.8 Atherosclerosis of other arteries	0.000	0.998	0.002
N82.9 Female genital tract fistula, unspecified	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.998	0.002
M24.03 Loose body in joint (Forearm)	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
G52.8 Disorders of other specified cranial nerves	0.002	0.998	0.000
G71 Primary disorders of muscles	0.002	0.998	0.000
I72 Other aneurysm	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.002	0.998	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.998	0.002
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.000	0.998	0.002
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.998	0.002
G95.2 Cord compression, unspecified	0.002	0.998	0.000
Z11.5 Special screening examination for other viral diseases	0.000	0.998	0.002
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.998	0.002
D69.6 Thrombocytopenia, unspecified	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.002	0.998	0.000
G54.0 Brachial plexus disorders	0.002	0.998	0.000
N82.8 Other female genital tract fistulae	0.002	0.998	0.000
N82.2 Fistula of vagina to small intestine	0.002	0.998	0.000
N82.1 Other female urinary-genital tract fistulae	0.002	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
N36.2 Urethral caruncle	0.000	0.998	0.002
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.002	0.998	0.000
S00.1 Contusion of eyelid and periocular area	0.000	0.998	0.002
S70.8 Other superficial injuries of hip and thigh	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.998	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
G54 Nerve root and plexus disorders	0.002	0.998	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.002	0.998	0.000
G53.0 Postzoster neuralgia	0.002	0.998	0.000
G72.3 Periodic paralysis	0.002	0.998	0.000
G72.2 Myopathy due to other toxic agents	0.002	0.998	0.000
G72.1 Alcoholic myopathy	0.002	0.998	0.000
I62.1 Nontraumatic extradural haemorrhage	0.000	0.998	0.002
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.998	0.002
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.998	0.002
H60 Otitis externa	0.002	0.998	0.000
G56.4 Causalgia	0.002	0.998	0.000
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.002	0.998	0.000
C62.1 Descended testis	0.002	0.998	0.000
G52.1 Disorders of glossopharyngeal nerve	0.002	0.998	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.002	0.998	0.000
I72.9 Aneurysm of unspecified site	0.000	0.998	0.002
N82.5 Female genital tract-skin fistulae	0.002	0.998	0.000
I00 Rheumatic fever without mention of heart involvement	0.000	0.998	0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.998	0.002
C62 Malignant neoplasm of testis	0.002	0.998	0.000
I02 Rheumatic chorea	0.000	0.998	0.002
I01 Rheumatic fever with heart involvement	0.000	0.998	0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.998	0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
G52.7 Disorders of multiple cranial nerves	0.002	0.998	0.000
G52.2 Disorders of vagus nerve	0.002	0.998	0.000
G52.0 Disorders of olfactory nerve	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
S99.9 Unspecified injury of ankle and foot	0.000	0.998	0.002
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
S01.9 Open wound of head, part unspecified	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.002	0.998	0.000
M24.51 Contracture of joint (Shoulder region)	0.001	0.998	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.998	0.002
G56.9 Mononeuropathy of upper limb, unspecified	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.000	0.998	0.002
H47.6 Disorders of visual cortex	0.000	0.998	0.002
H47.5 Disorders of other visual pathways	0.000	0.998	0.002
H47.4 Disorders of optic chiasm	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
X50.2 School, other institution and public administrative area	0.002	0.998	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
H60.2 Malignant otitis externa	0.002	0.998	0.000
I72.2 Aneurysm of renal artery	0.000	0.998	0.002
Q52.5 Fusion of labia	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.998	0.001
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.998	0.002
G54.4 Lumbosacral root disorders, not elsewhere classified	0.002	0.998	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.002	0.998	0.000
G54.8 Other nerve root and plexus disorders	0.002	0.998	0.000
G71.9 Primary disorder of muscle, unspecified	0.002	0.998	0.000
G71.8 Other primary disorders of muscles	0.002	0.998	0.000
G71.2 Congenital myopathies	0.002	0.998	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.998	0.002
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.998	0.002
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.002	0.998	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.002	0.998	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.002	0.998	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.998	0.001
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.001
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.998	0.001
I79.1 Aortitis in diseases classified elsewhere	0.000	0.998	0.001
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.998	0.001
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
H60.8 Other otitis externa	0.002	0.998	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
H60.0 Abscess of external ear	0.002	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
Q52.9 Congenital malformation of female genitalia, unspecified	0.001	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.001	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.001	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.001	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.001	0.998	0.000
Q52.3 Imperforate hymen	0.001	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.001	0.998	0.000
Q52.1 Doubling of vagina	0.001	0.998	0.000
Q52.0 Congenital absence of vagina	0.001	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
G54.7 Phantom limb syndrome without pain	0.002	0.998	0.000
G54.5 Neuralgic amyotrophy	0.002	0.998	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.002	0.998	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.002	0.998	0.000
G54.1 Lumbosacral plexus disorders	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.000	0.998	0.002
Q55.9 Congenital malformation of male genital organ, unspecified	0.001	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.001	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.001	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.001	0.998	0.000
Q55.3 Atresia of vas deferens	0.001	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.001	0.998	0.000
Q55.0 Absence and aplasia of testis	0.001	0.998	0.000
S70.0 Contusion of hip	0.002	0.998	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.998	0.001
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
I72.1 Aneurysm of artery of upper extremity	0.000	0.998	0.001
N82.4 Other female intestinal-genital tract fistulae	0.001	0.998	0.000
Q55.6 Other congenital malformations of penis	0.001	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.001
S06 Intracranial injury	0.000	0.998	0.002
G71.1 Myotonic disorders	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
C62.0 Undescended testis	0.001	0.998	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations