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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35615859
log Bayes Factor = 14.2527
Chromosome 1   position 49,057,717  (GRCh37) Explore rs35615859 on Ensembl!
Variant rs35615859 is part of Cluster X0054

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
N92 Excessive, frequent and irregular menstruation
1.000 0.000 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
L03 Cellulitis
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
N60-N64 Disorders of breast
0.986 0.014 0.000
I73 Other peripheral vascular diseases
0.986 0.014 0.000
L03.1 Cellulitis of other parts of limb
0.982 0.018 0.000
I73.9 Peripheral vascular disease, unspecified
0.981 0.019 0.000
I44 Atrioventricular and left bundle-branch block
0.981 0.019 0.000
B95-B98 Bacterial, viral and other infectious agents
0.979 0.021 0.000
N17-N19 Renal failure
0.973 0.027 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.965 0.035 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.959 0.041 0.000
N80 Endometriosis
0.950 0.050 0.000
I47 Paroxysmal tachycardia
0.947 0.053 0.000
Chapter VIII Diseases of the ear and mastoid process
0.944 0.056 0.000
D60-D64 Aplastic and other anaemias
0.943 0.057 0.000
D50-D53 Nutritional anaemias
0.938 0.062 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.935 0.065 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.932 0.068 0.000
I77 Other disorders of arteries and arterioles
0.931 0.069 0.000
N18 Chronic renal failure
0.922 0.078 0.000
I44.1 Atrioventricular block, second degree
0.921 0.079 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.921 0.079 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.916 0.084 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.916 0.084 0.000
N63 Unspecified lump in breast
0.915 0.085 0.000
I51 Complications and ill-defined descriptions of heart disease
0.906 0.094 0.000
D64 Other anaemias
0.906 0.094 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.903 0.097 0.000
A30-A49 Other bacterial diseases
0.902 0.098 0.000
N18.9 Chronic renal failure, unspecified
0.901 0.099 0.000
N62 Hypertrophy of breast
0.898 0.102 0.000
D50 Iron deficiency anaemia
0.895 0.105 0.000
I74 Arterial embolism and thrombosis
0.892 0.108 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.890 0.110 0.000
N60 Benign mammary dysplasia
0.887 0.113 0.000
Chapter XXI Factors influencing health status and contact with health services
0.884 0.116 0.000
L03.0 Cellulitis of finger and toe
0.883 0.117 0.000
D64.9 Anaemia, unspecified
0.880 0.120 0.000
N80.1 Endometriosis of ovary
0.879 0.121 0.000
I35 Nonrheumatic aortic valve disorders
0.874 0.126 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.870 0.130 0.000
Chapter XX External causes of morbidity and mortality
0.869 0.131 0.000
N95 Menopausal and other perimenopausal disorders
0.869 0.131 0.000
N93 Other abnormal uterine and vaginal bleeding
0.866 0.134 0.000
I44.2 Atrioventricular block, complete
0.863 0.137 0.000
S80-S89 Injuries to the knee and lower leg
0.860 0.140 0.000
I47.1 Supraventricular tachycardia
0.852 0.148 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.851 0.149 0.000
I47.2 Ventricular tachycardia
0.843 0.157 0.000
M20-M25 Other joint disorders
0.842 0.158 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.842 0.158 0.000
I77.1 Stricture of artery
0.839 0.161 0.000
L60-L75 Disorders of skin appendages
0.839 0.161 0.000
L05 Pilonidal cyst
0.838 0.162 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.836 0.164 0.000
D50.9 Iron deficiency anaemia, unspecified
0.836 0.164 0.000
H90-H95 Other disorders of ear
0.835 0.165 0.000
L03.3 Cellulitis of trunk
0.835 0.165 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.834 0.166 0.000
T66-T78 Other and unspecified effects of external causes
0.834 0.166 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.833 0.167 0.000
G90-G99 Other disorders of the nervous system
0.832 0.168 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.832 0.168 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.829 0.171 0.000
N19 Unspecified renal failure
0.825 0.175 0.000
I42 Cardiomyopathy
0.825 0.175 0.000
N92.3 Ovulation bleeding
0.824 0.176 0.000
N20-N23 Urolithiasis
0.824 0.176 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.821 0.179 0.000
N80.9 Endometriosis, unspecified
0.820 0.179 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.820 0.180 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.818 0.182 0.000
N99-N99 Other disorders of the genitourinary system
0.817 0.183 0.000
I05-I09 Chronic rheumatic heart diseases
0.815 0.185 0.000
I78 Diseases of capillaries
0.814 0.185 0.000
I45 Other conduction disorders
0.812 0.188 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.811 0.189 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.810 0.190 0.000
G35 Multiple sclerosis
0.809 0.191 0.000
N92.6 Irregular menstruation, unspecified
0.805 0.195 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.804 0.196 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.802 0.198 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.801 0.199 0.000
I51.8 Other ill-defined heart diseases
0.798 0.202 0.000
G20-G26 Extrapyramidal and movement disorders
0.798 0.202 0.000
S50-S59 Injuries to the elbow and forearm
0.798 0.202 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.797 0.203 0.000
M45-M49 Spondylopathies
0.795 0.205 0.000
T82.3 Mechanical complication of other vascular grafts
0.793 0.207 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.793 0.207 0.000
S70-S79 Injuries to the hip and thigh
0.792 0.207 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.792 0.208 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.791 0.209 0.000
B99-B99 Other infectious diseases
0.788 0.212 0.000
N80.0 Endometriosis of uterus
0.787 0.213 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.786 0.214 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.786 0.214 0.000
A49 Bacterial infection of unspecified site
0.785 0.215 0.000
I51.7 Cardiomegaly
0.785 0.215 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.785 0.215 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.783 0.217 0.000
I44.0 Atrioventricular block, first degree
0.783 0.217 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.781 0.219 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.781 0.219 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.779 0.221 0.000
H80-H83 Diseases of inner ear
0.778 0.222 0.000
S80 Superficial injury of lower leg
0.778 0.222 0.000
N17 Acute renal failure
0.777 0.223 0.000
L90 Atrophic disorders of skin
0.776 0.224 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.772 0.228 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.771 0.229 0.000
I44.6 Other and unspecified fascicular block
0.768 0.232 0.000
I72 Other aneurysm
0.767 0.233 0.000
N00-N08 Glomerular diseases
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.762 0.238 0.000
S40-S49 Injuries to the shoulder and upper arm
0.760 0.240 0.000
M20 Acquired deformities of fingers and toes
0.760 0.240 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.760 0.240 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.758 0.242 0.000
T86 Failure and rejection of transplanted organs and tissues
0.758 0.242 0.000
H65-H75 Diseases of middle ear and mastoid
0.757 0.243 0.000
N21 Calculus of lower urinary tract
0.757 0.243 0.000
G95 Other diseases of spinal cord
0.757 0.243 0.000
H90 Conductive and sensorineural hearing loss
0.754 0.246 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.754 0.246 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.751 0.249 0.000
L90.5 Scar conditions and fibrosis of skin
0.751 0.249 0.000
I84 Haemorrhoids
0.751 0.249 0.000
N95.2 Postmenopausal atrophic vaginitis
0.749 0.251 0.000
N25-N29 Other disorders of kidney and ureter
0.747 0.253 0.000
I46 Cardiac arrest
0.743 0.257 0.000
S10-S19 Injuries to the neck
0.742 0.258 0.000
G40-G47 Episodic and paroxysmal disorders
0.740 0.260 0.000
D62 Acute posthaemorrhagic anaemia
0.738 0.262 0.000
I30 Acute pericarditis
0.736 0.264 0.000
N60.3 Fibrosclerosis of breast
0.736 0.264 0.000
I44.7 Left bundle-branch block, unspecified
0.735 0.265 0.000
L05.9 Pilonidal cyst without abscess
0.734 0.266 0.000
D50.8 Other iron deficiency anaemias
0.733 0.267 0.000
D80-D89 Certain disorders involving the immune mechanism
0.732 0.268 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.730 0.270 0.000
N88 Other noninflammatory disorders of cervix uteri
0.730 0.270 0.000
M21 Other acquired deformities of limbs
0.729 0.271 0.000
L89 Decubitus ulcer
0.727 0.273 0.000
D52 Folate deficiency anaemia
0.727 0.273 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.725 0.275 0.000
M47 Spondylosis
0.724 0.276 0.000
G59.0 Diabetic mononeuropathy
0.724 0.276 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.276 0.000
B25-B34 Other viral diseases
0.724 0.276 0.000
N60.2 Fibroadenosis of breast
0.723 0.277 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.723 0.277 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.722 0.278 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.721 0.279 0.000
N61 Inflammatory disorders of breast
0.721 0.279 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.719 0.281 0.000
L03.2 Cellulitis of face
0.719 0.281 0.000
T78 Adverse effects, not elsewhere classified
0.719 0.281 0.000
N92.4 Excessive bleeding in the premenopausal period
0.719 0.281 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.719 0.281 0.000
M40-M43 Deforming dorsopathies
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
N92.5 Other specified irregular menstruation
0.717 0.283 0.000
N92.2 Excessive menstruation at puberty
0.717 0.283 0.000
I77.6 Arteritis, unspecified
0.717 0.283 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.716 0.284 0.000
I70 Atherosclerosis
0.716 0.284 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
I84.1 Internal haemorrhoids with other complications
0.716 0.284 0.000
L04 Acute lymphadenitis
0.715 0.285 0.000
L01 Impetigo
0.715 0.285 0.000
L00 Staphylococcal scalded skin syndrome
0.715 0.285 0.000
A40 Streptococcal septicaemia
0.715 0.285 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.714 0.286 0.000
L03.9 Cellulitis, unspecified
0.714 0.286 0.000
H60-H62 Diseases of external ear
0.713 0.286 0.000
A41 Other septicaemia
0.713 0.287 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
M25 Other joint disorders, not elsewhere classified
0.713 0.287 0.000
L03.8 Cellulitis of other sites
0.712 0.287 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.288 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.712 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
I33 Acute and subacute endocarditis
0.712 0.288 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.712 0.288 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.711 0.289 0.000
T82.1 Mechanical complication of cardiac electronic device
0.710 0.290 0.000
N18.5 Chronic kidney disease, stage 5
0.710 0.290 0.000
Z22 Carrier of infectious disease
0.710 0.290 0.000
N21.0 Calculus in bladder
0.710 0.290 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
B65-B83 Helminthiases
0.710 0.290 0.000
B50-B64 Protozoal diseases
0.710 0.290 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A80-A89 Viral infections of the central nervous system
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
A15-A19 Tuberculosis
0.710 0.290 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.710 0.290 0.000
Chapter XXII Codes for special purposes
0.709 0.291 0.000
W00-W19 Falls
0.709 0.291 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.709 0.291 0.000
I74.5 Embolism and thrombosis of iliac artery
0.708 0.292 0.000
I73.8 Other specified peripheral vascular diseases
0.707 0.293 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.707 0.293 0.000
H92 Otalgia and effusion of ear
0.707 0.293 0.000
D69 Purpura and other haemorrhagic conditions
0.705 0.294 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.705 0.295 0.000
G82 Paraplegia and tetraplegia
0.705 0.295 0.000
I44.5 Left posterior fascicular block
0.703 0.296 0.000
I44.4 Left anterior fascicular block
0.703 0.296 0.000
I44.3 Other and unspecified atrioventricular block
0.703 0.296 0.000
N60.8 Other benign mammary dysplasias
0.700 0.300 0.000
M86-M90 Other osteopathies
0.699 0.301 0.000
M80-M85 Disorders of bone density and structure
0.699 0.301 0.000
N94.6 Dysmenorrhoea, unspecified
0.698 0.302 0.000
B15-B19 Viral hepatitis
0.697 0.303 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.697 0.303 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.695 0.305 0.000
N60.4 Mammary duct ectasia
0.694 0.306 0.000
N18.0 End-stage renal disease
0.693 0.307 0.000
T87 Complications peculiar to reattachment and amputation
0.692 0.308 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.692 0.308 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.692 0.308 0.000
G58 Other mononeuropathies
0.691 0.309 0.000
G50 Disorders of trigeminal nerve
0.691 0.309 0.000
M20.5 Other deformities of toe(s) (acquired)
0.691 0.309 0.000
I35.0 Aortic (valve) stenosis
0.691 0.309 0.000
I84.4 External haemorrhoids with other complications
0.690 0.310 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.689 0.311 0.000
I42.9 Cardiomyopathy, unspecified
0.689 0.311 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.688 0.312 0.000
N89 Other noninflammatory disorders of vagina
0.688 0.312 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.688 0.312 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.688 0.312 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.688 0.312 0.000
T91 Sequelae of injuries of neck and trunk
0.687 0.313 0.000
N95.0 Postmenopausal bleeding
0.687 0.313 0.000
D61 Other aplastic anaemias
0.686 0.314 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.686 0.314 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.685 0.315 0.000
N93.0 Postcoital and contact bleeding
0.685 0.315 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.683 0.317 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.683 0.317 0.000
I78.1 Naevus, nonneoplastic
0.682 0.317 0.000
I08 Multiple valve diseases
0.682 0.318 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.682 0.318 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.681 0.319 0.000
N80.6 Endometriosis in cutaneous scar
0.681 0.319 0.000
N80.5 Endometriosis of intestine
0.681 0.319 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.681 0.319 0.000
N80.2 Endometriosis of Fallopian tube
0.681 0.319 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.679 0.321 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.679 0.321 0.000
Z04 Examination and observation for other reasons
0.679 0.321 0.000
T79-T79 Certain early complications of trauma
0.679 0.321 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.679 0.321 0.000
I47.0 Reentry ventricular arrhythmia
0.679 0.321 0.000
S80.8 Other superficial injuries of lower leg
0.679 0.321 0.000
I35.8 Other aortic valve disorders
0.679 0.321 0.000
N80.8 Other endometriosis
0.678 0.322 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.677 0.323 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.676 0.323 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.676 0.324 0.000
M47.8 Other spondylosis
0.675 0.325 0.000
G95.8 Other specified diseases of spinal cord
0.675 0.325 0.000
I87 Other disorders of veins
0.674 0.326 0.000
Y85 Sequelae of transport accidents
0.674 0.326 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.674 0.326 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.674 0.326 0.000
W20-W49 Exposure to inanimate mechanical forces
0.674 0.326 0.000
D53 Other nutritional anaemias
0.673 0.327 0.000
S79 Other and unspecified injuries of hip and thigh
0.673 0.327 0.000
I45.3 Trifascicular block
0.672 0.328 0.000
V10-V19 Pedal cyclist injured in transport accident
0.671 0.329 0.000
G40 Epilepsy
0.671 0.329 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.670 0.330 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.670 0.330 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.670 0.330 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.670 0.330 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.670 0.330 0.000
H81 Disorders of vestibular function
0.670 0.330 0.000
A49.8 Other bacterial infections of unspecified site
0.670 0.330 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.668 0.331 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.668 0.331 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.668 0.331 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.668 0.331 0.000
I77.8 Other specified disorders of arteries and arterioles
0.667 0.333 0.000
I77.5 Necrosis of artery
0.667 0.333 0.000
I77.4 Coeliac artery compression syndrome
0.667 0.333 0.000
I77.3 Arterial fibromuscular dysplasia
0.667 0.333 0.000
I77.2 Rupture of artery
0.667 0.333 0.000
I77.0 Arteriovenous fistula, acquired
0.667 0.333 0.000
G37 Other demyelinating diseases of central nervous system
0.667 0.333 0.000
G56 Mononeuropathies of upper limb
0.666 0.334 0.000
N18.4 Chronic kidney disease, stage 4
0.663 0.337 0.000
I81 Portal vein thrombosis
0.663 0.337 0.000
N18.8 Other chronic renal failure
0.661 0.339 0.000
N18.1 Chronic kidney disease, stage 1
0.661 0.339 0.000
S81 Open wound of lower leg
0.661 0.339 0.000
L60 Nail disorders
0.660 0.340 0.000
D75 Other diseases of blood and blood-forming organs
0.660 0.340 0.000
M60-M63 Disorders of muscles
0.660 0.340 0.000
M00-M03 Infectious arthropathies
0.660 0.340 0.000
Chapter XI Diseases of the digestive system
0.660 0.340 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.659 0.341 0.000
D69.6 Thrombocytopenia, unspecified
0.659 0.341 0.000
N90.5 Atrophy of vulva
0.659 0.341 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.658 0.342 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.657 0.343 0.000
G54 Nerve root and plexus disorders
0.657 0.343 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.657 0.343 0.000
G52 Disorders of other cranial nerves
0.657 0.343 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.657 0.343 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.657 0.343 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.657 0.343 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.657 0.343 0.000
S20-S29 Injuries to the thorax
0.656 0.344 0.000
N23 Unspecified renal colic
0.655 0.344 0.000
L50-L54 Urticaria and erythema
0.655 0.345 0.000
M25.4 Effusion of joint
0.654 0.346 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.653 0.347 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.653 0.347 0.000
Chapter VII Diseases of the eye and adnexa
0.650 0.350 0.000
I51.6 Cardiovascular disease, unspecified
0.650 0.350 0.000
I51.5 Myocardial degeneration
0.650 0.350 0.000
I51.4 Myocarditis, unspecified
0.650 0.350 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.650 0.350 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.650 0.350 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.650 0.350 0.000
I51.0 Cardiac septal defect, acquired
0.650 0.350 0.000
D64.8 Other specified anaemias
0.650 0.350 0.000
D64.4 Congenital dyserythropoietic anaemia
0.650 0.350 0.000
D64.3 Other sideroblastic anaemias
0.650 0.350 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.650 0.350 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.650 0.350 0.000
D64.0 Hereditary sideroblastic anaemia
0.650 0.350 0.000
M35 Other systemic involvement of connective tissue
0.650 0.350 0.000
N18.2 Chronic kidney disease, stage 2
0.649 0.350 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.649 0.351 0.000
G20 Parkinson's disease
0.649 0.351 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.648 0.352 0.000
Z22.3 Carrier of other specified bacterial diseases
0.648 0.352 0.000
Z03.4 Observation for suspected myocardial infarction
0.648 0.352 0.000
M50-M54 Other dorsopathies
0.647 0.353 0.000
A48 Other bacterial diseases, not elsewhere classified
0.647 0.353 0.000
A44 Bartonellosis
0.647 0.353 0.000
A43 Nocardiosis
0.647 0.353 0.000
A42 Actinomycosis
0.647 0.353 0.000
A39 Meningococcal infection
0.647 0.353 0.000
A37 Whooping cough
0.647 0.353 0.000
A36 Diphtheria
0.647 0.353 0.000
A32 Listeriosis
0.647 0.353 0.000
A31 Infection due to other mycobacteria
0.647 0.353 0.000
A30 Leprosy [Hansen's disease]
0.647 0.353 0.000
A46 Erysipelas
0.647 0.353 0.000
A38 Scarlet fever
0.647 0.353 0.000
A35 Other tetanus
0.647 0.353 0.000
A34 Obstetrical tetanus
0.647 0.353 0.000
A33 Tetanus neonatorum
0.647 0.353 0.000
T93 Sequelae of injuries of lower limb
0.644 0.355 0.000
L81 Other disorders of pigmentation
0.644 0.356 0.000
N10-N16 Renal tubulo-interstitial diseases
0.644 0.356 0.000
G30-G32 Other degenerative diseases of the nervous system
0.643 0.357 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.643 0.357 0.000
B99 Other and unspecified infectious diseases
0.642 0.357 0.000
T92 Sequelae of injuries of upper limb
0.642 0.358 0.000
D50.1 Sideropenic dysphagia
0.642 0.358 0.000
L83 Acanthosis nigricans
0.640 0.360 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.640 0.360 0.000
I74.8 Embolism and thrombosis of other arteries
0.640 0.360 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.640 0.360 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.640 0.360 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.640 0.360 0.000
S52 Fracture of forearm
0.640 0.360 0.000
H92.0 Otalgia
0.639 0.361 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.639 0.361 0.000
G36 Other acute disseminated demyelination
0.638 0.362 0.000
I85 Oesophageal varices
0.638 0.362 0.000
N17.9 Acute renal failure, unspecified
0.637 0.363 0.000
N64 Other disorders of breast
0.636 0.364 0.000
N60.9 Benign mammary dysplasia, unspecified
0.636 0.364 0.000
Z29 Need for other prophylactic measures
0.634 0.366 0.000
I71 Aortic aneurysm and dissection
0.634 0.366 0.000
H90.5 Sensorineural hearing loss, unspecified
0.634 0.366 0.000
M24 Other specific joint derangements
0.632 0.367 0.000
H73 Other disorders of tympanic membrane
0.632 0.368 0.000
G57 Mononeuropathies of lower limb
0.631 0.369 0.000
N90.6 Hypertrophy of vulva
0.630 0.370 0.000
I35.1 Aortic (valve) insufficiency
0.629 0.371 0.000
T31 Burns classified according to extent of body surface involved
0.629 0.371 0.000
L73 Other follicular disorders
0.629 0.371 0.000
I35.9 Aortic valve disorder, unspecified
0.627 0.373 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.627 0.373 0.000
H90.0 Conductive hearing loss, bilateral
0.625 0.374 0.000
N94.1 Dyspareunia
0.625 0.375 0.000
G96 Other disorders of central nervous system
0.625 0.375 0.000
D51 Vitamin B12 deficiency anaemia
0.624 0.375 0.000
A49.0 Staphylococcal infection, unspecified
0.625 0.375 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.624 0.376 0.000
I34 Nonrheumatic mitral valve disorders
0.624 0.376 0.000
Z10 Routine general health check-up of defined subpopulation
0.624 0.376 0.000
D68 Other coagulation defects
0.624 0.376 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.623 0.377 0.000
Y35-Y36 Legal intervention and operations of war
0.623 0.377 0.000
Y10-Y34 Event of undetermined intent
0.623 0.377 0.000
Y00-Y09 Assault
0.623 0.377 0.000
X85-X99 Assault
0.623 0.377 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.623 0.377 0.000
X50-X57 Overexertion, travel and privation
0.623 0.377 0.000
X30-X39 Exposure to forces of nature
0.623 0.377 0.000
X20-X29 Contact with venomous animals and plants
0.623 0.377 0.000
X10-X19 Contact with heat and hot substances
0.623 0.377 0.000
X00-X09 Exposure to smoke, fire and flames
0.623 0.377 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.623 0.377 0.000
W75-W84 Other accidental threats to breathing
0.623 0.377 0.000
W65-W74 Accidental drowning and submersion
0.623 0.377 0.000
W50-W64 Exposure to animate mechanical forces
0.623 0.377 0.000
V98-V99 Other and unspecified transport accidents
0.623 0.377 0.000
V95-V97 Air and space transport accidents
0.623 0.377 0.000
V90-V94 Water transport accidents
0.623 0.377 0.000
V80-V89 Other land transport accidents
0.623 0.377 0.000
V70-V79 Bus occupant injured in transport accident
0.623 0.377 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.623 0.377 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.623 0.377 0.000
V40-V49 Car occupant injured in transport accident
0.623 0.377 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.623 0.377 0.000
V01-V09 Pedestrian injured in transport accident
0.623 0.377 0.000
T81 Complications of procedures, not elsewhere classified
0.623 0.377 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.623 0.377 0.000
N95.3 States associated with artificial menopause
0.623 0.377 0.000
N95.1 Menopausal and female climacteric states
0.623 0.377 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.622 0.378 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.622 0.378 0.000
I42.0 Dilated cardiomyopathy
0.621 0.379 0.000
S60-S69 Injuries to the wrist and hand
0.620 0.380 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.619 0.381 0.000
T88.4 Failed or difficult intubation
0.619 0.381 0.000
G51 Facial nerve disorders
0.618 0.382 0.000
Y86 Sequelae of other accidents
0.618 0.382 0.000
N60.0 Solitary cyst of breast
0.617 0.383 0.000
G95.2 Cord compression, unspecified
0.617 0.383 0.000
S89 Other and unspecified injuries of lower leg
0.616 0.384 0.000
S88 Traumatic amputation of lower leg
0.616 0.384 0.000
S87 Crushing injury of lower leg
0.616 0.384 0.000
S86 Injury of muscle and tendon at lower leg level
0.616 0.384 0.000
S85 Injury of blood vessels at lower leg level
0.616 0.384 0.000
S84 Injury of nerves at lower leg level
0.616 0.384 0.000
I45.9 Conduction disorder, unspecified
0.615 0.385 0.000
M65-M68 Disorders of synovium and tendon
0.615 0.385 0.000
G82.2 Paraplegia, unspecified
0.615 0.385 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.614 0.386 0.000
I38 Endocarditis, valve unspecified
0.613 0.387 0.000
M21.0 Valgus deformity, not elsewhere classified
0.613 0.387 0.000
I50 Heart failure
0.613 0.387 0.000
G61 Inflammatory polyneuropathy
0.613 0.387 0.000
Z03.3 Observation for suspected nervous system disorder
0.612 0.388 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.612 0.388 0.000
M25.46 Effusion of joint (Lower leg)
0.612 0.388 0.000
L84 Corns and callosities
0.611 0.389 0.000
K70-K77 Diseases of liver
0.610 0.390 0.000
M47.82 Other spondylosis (Cervical region)
0.610 0.390 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.609 0.391 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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