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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs356971
log Bayes Factor = 170.044
Chromosome 6   position 29,979,797  (GRCh37) Explore rs356971 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
M07.3 Other psoriatic arthropathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
1.000 0.000 0.000
K51 Ulcerative colitis
0.000 0.000 1.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
C34 Malignant neoplasm of bronchus and lung
0.999 0.001 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.001 0.999
M07.39 Other psoriatic arthropathies (Site unspecified)
0.999 0.001 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
L40-L45 Papulosquamous disorders
0.999 0.001 0.000
M07 Psoriatic and enteropathic arthropathies
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
G35 Multiple sclerosis
0.998 0.002 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.996 0.004 0.000
E16.2 Hypoglycaemia, unspecified
0.995 0.005 0.000
B37 Candidiasis
0.994 0.006 0.000
C34.3 Lower lobe, bronchus or lung
0.994 0.006 0.000
B35-B49 Mycoses
0.993 0.007 0.000
E10.3 With ophthalmic complications
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.009 0.991
E14 Unspecified diabetes mellitus
0.987 0.013 0.000
B37.0 Candidal stomatitis
0.983 0.017 0.000
E10.1 With ketoacidosis
0.983 0.017 0.000
G30-G32 Other degenerative diseases of the nervous system
0.982 0.018 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.982 0.018 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.019 0.981
C15-C26 Malignant neoplasms of digestive organs
0.978 0.022 0.000
C18 Malignant neoplasm of colon
0.977 0.023 0.000
M86-M90 Other osteopathies
0.977 0.023 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.977 0.023 0.000
E11 Non-insulin-dependent diabetes mellitus
0.976 0.024 0.000
Chapter VII Diseases of the eye and adnexa
0.976 0.024 0.000
K50-K52 Noninfective enteritis and colitis
0.014 0.025 0.961
C02 Malignant neoplasm of other and unspecified parts of tongue
0.974 0.026 0.000
K90 Intestinal malabsorption
0.974 0.026 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.973 0.027 0.000
M20-M25 Other joint disorders
0.971 0.029 0.000
B37.8 Candidiasis of other sites
0.968 0.032 0.000
M35 Other systemic involvement of connective tissue
0.965 0.035 0.000
B37.9 Candidiasis, unspecified
0.963 0.037 0.000
M35.0 Sicca syndrome [Sjogren]
0.961 0.039 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.961 0.039 0.000
E14.3 With ophthalmic complications
0.961 0.039 0.000
E10.2 With renal complications
0.960 0.040 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.959 0.041 0.000
N13 Obstructive and reflux uropathy
0.958 0.042 0.000
K50 Crohn's disease [regional enteritis]
0.001 0.042 0.958
M60-M63 Disorders of muscles
0.958 0.042 0.000
K51.4 Pseudopolyposis of colon
0.000 0.042 0.958
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.955 0.045 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.952 0.048 0.000
N10-N16 Renal tubulo-interstitial diseases
0.952 0.048 0.000
Chapter XIV Diseases of the genitourinary system
0.950 0.050 0.000
K50.9 Crohn's disease, unspecified
0.000 0.052 0.948
C18.9 Colon, unspecified
0.947 0.053 0.000
C91 Lymphoid leukaemia
0.946 0.054 0.000
N00-N08 Glomerular diseases
0.945 0.055 0.000
H47.3 Other disorders of optic disk
0.939 0.061 0.000
C02.9 Tongue, unspecified
0.938 0.062 0.000
E83.1 Disorders of iron metabolism
0.000 0.063 0.937
C18.7 Sigmoid colon
0.937 0.063 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.935 0.065 0.000
H46 Optic neuritis
0.934 0.066 0.000
H30-H36 Disorders of choroid and retina
0.933 0.067 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.933 0.067 0.000
H47.2 Optic atrophy
0.929 0.071 0.000
M86 Osteomyelitis
0.928 0.072 0.000
M62 Other disorders of muscle
0.926 0.074 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.075 0.925
M07.36 Other psoriatic arthropathies (Lower leg)
0.924 0.076 0.000
C04 Malignant neoplasm of floor of mouth
0.919 0.081 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.915 0.085 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.909 0.091 0.000
E11.5 With peripheral circulatory complications
0.907 0.093 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.905 0.095 0.000
H36 Retinal disorders in diseases classified elsewhere
0.902 0.098 0.000
G31.8 Other specified degenerative diseases of nervous system
0.901 0.099 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.900 0.100 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.900 0.100 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.897 0.103 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.896 0.104 0.000
M89 Other disorders of bone
0.894 0.106 0.000
K90-K93 Other diseases of the digestive system
0.892 0.108 0.000
N04 Nephrotic syndrome
0.892 0.108 0.000
C18.6 Descending colon
0.891 0.109 0.000
C85.1 B-cell lymphoma, unspecified
0.891 0.109 0.000
C77.1 Intrathoracic lymph nodes
0.889 0.111 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.888 0.112 0.000
M62.8 Other specified disorders of muscle
0.887 0.113 0.000
C91.1 Chronic lymphocytic leukaemia
0.885 0.115 0.000
Chapter XI Diseases of the digestive system
0.885 0.115 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.885 0.115 0.000
H34 Retinal vascular occlusions
0.883 0.117 0.000
G31.0 Circumscribed brain atrophy
0.882 0.118 0.000
C84.5 Other and unspecified T-cell lymphomas
0.881 0.119 0.000
H36.0 Diabetic retinopathy
0.880 0.120 0.000
D00-D09 In situ neoplasms
0.878 0.122 0.000
E11.1 With ketoacidosis
0.878 0.122 0.000
C34.0 Main bronchus
0.875 0.125 0.000
C34.2 Middle lobe, bronchus or lung
0.875 0.125 0.000
K70-K77 Diseases of liver
0.873 0.127 0.000
C34.1 Upper lobe, bronchus or lung
0.871 0.129 0.000
N11 Chronic tubulo-interstitial nephritis
0.871 0.129 0.000
M31 Other necrotising vasculopathies
0.871 0.129 0.000
K75 Other inflammatory liver diseases
0.868 0.132 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.867 0.133 0.000
C18.1 Appendix
0.867 0.133 0.000
E70-E90 Metabolic disorders
0.866 0.134 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.865 0.135 0.000
E11.2 With renal complications
0.865 0.135 0.000
M86.9 Osteomyelitis, unspecified
0.864 0.136 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.863 0.137 0.000
A15-A19 Tuberculosis
0.860 0.140 0.000
K75.4 Autoimmune hepatitis
0.859 0.141 0.000
E14.5 With peripheral circulatory complications
0.858 0.142 0.000
L10-L14 Bullous disorders
0.857 0.143 0.000
N40 Hyperplasia of prostate
0.000 0.149 0.851
L40.0 Psoriasis vulgaris
0.850 0.150 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.847 0.153 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.845 0.155 0.000
E10.4 With neurological complications
0.839 0.161 0.000
H53-H54 Visual disturbances and blindness
0.838 0.162 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.838 0.162 0.000
D04 Carcinoma in situ of skin
0.838 0.162 0.000
K75.8 Other specified inflammatory liver diseases
0.836 0.164 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.834 0.166 0.000
C18.4 Transverse colon
0.833 0.167 0.000
K90.9 Intestinal malabsorption, unspecified
0.832 0.168 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.832 0.168 0.000
C38.4 Pleura
0.829 0.171 0.000
L50-L54 Urticaria and erythema
0.829 0.171 0.000
N04.9 Unspecified
0.826 0.174 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.825 0.175 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.825 0.175 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.824 0.176 0.000
C81 Hodgkin's disease
0.823 0.177 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.823 0.177 0.000
L40.1 Generalised pustular psoriasis
0.822 0.178 0.000
C04.9 Floor of mouth, unspecified
0.822 0.178 0.000
H34.8 Other retinal vascular occlusions
0.822 0.178 0.000
N13.6 Pyonephrosis
0.821 0.179 0.000
L94 Other localised connective tissue disorders
0.820 0.180 0.000
D60-D64 Aplastic and other anaemias
0.819 0.181 0.000
L93 Lupus erythematosus
0.818 0.182 0.000
D80-D89 Certain disorders involving the immune mechanism
0.818 0.182 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.817 0.183 0.000
K50.8 Other Crohn's disease
0.000 0.184 0.816
G50-G59 Nerve, nerve root and plexus disorders
0.813 0.187 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.813 0.187 0.000
C84.0 Mycosis fungoides
0.813 0.187 0.000
N05 Unspecified nephritic syndrome
0.813 0.187 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.812 0.188 0.000
G30 Alzheimer's disease
0.810 0.190 0.000
M35.7 Hypermobility syndrome
0.809 0.190 0.000
M32 Systemic lupus erythematosus
0.806 0.194 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.805 0.195 0.000
M91-M94 Chondropathies
0.805 0.195 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.804 0.196 0.000
E11.7 With multiple complications
0.804 0.196 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.196 0.804
B20-B24 Human immunodeficiency virus [HIV] disease
0.801 0.199 0.000
M10 Gout
0.800 0.200 0.000
E10.7 With multiple complications
0.799 0.201 0.000
G70-G73 Diseases of myoneural junction and muscle
0.798 0.202 0.000
C13 Malignant neoplasm of hypopharynx
0.797 0.203 0.000
C09 Malignant neoplasm of tonsil
0.796 0.204 0.000
B37.2 Candidiasis of skin and nail
0.796 0.204 0.000
H30 Chorioretinal inflammation
0.796 0.204 0.000
A20-A28 Certain zoonotic bacterial diseases
0.796 0.204 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.795 0.205 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.794 0.206 0.000
E78.2 Mixed hyperlipidaemia
0.792 0.208 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.791 0.209 0.000
E07 Other disorders of thyroid
0.791 0.209 0.000
C91.9 Lymphoid leukaemia, unspecified
0.791 0.209 0.000
C34.9 Bronchus or lung, unspecified
0.790 0.210 0.000
K50.1 Crohn's disease of large intestine
0.000 0.211 0.789
E13 Other specified diabetes mellitus
0.788 0.211 0.000
C83.3 Large cell (diffuse)
0.787 0.213 0.000
E50-E64 Other nutritional deficiencies
0.787 0.213 0.000
D06 Carcinoma in situ of cervix uteri
0.786 0.214 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.786 0.214 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.786 0.214 0.000
G56 Mononeuropathies of upper limb
0.784 0.216 0.000
G56.0 Carpal tunnel syndrome
0.784 0.216 0.000
K72 Hepatic failure, not elsewhere classified
0.783 0.217 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.782 0.218 0.000
M89.5 Osteolysis
0.780 0.220 0.000
C88 Malignant immunoproliferative diseases
0.779 0.221 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.776 0.224 0.000
E14.8 With unspecified complications
0.774 0.226 0.000
C01 Malignant neoplasm of base of tongue
0.773 0.227 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.772 0.228 0.000
M34 Systemic sclerosis
0.771 0.229 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.770 0.230 0.000
G37 Other demyelinating diseases of central nervous system
0.770 0.230 0.000
K51.8 Other ulcerative colitis
0.000 0.230 0.770
C77.0 Lymph nodes of head, face and neck
0.770 0.230 0.000
C04.0 Anterior floor of mouth
0.770 0.230 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.769 0.231 0.000
K73 Chronic hepatitis, not elsewhere classified
0.768 0.232 0.000
L40.3 Pustulosis palmaris et plantaris
0.768 0.232 0.000
M33 Dermatopolymyositis
0.767 0.233 0.000
C02.1 Border of tongue
0.767 0.233 0.000
E11.6 With other specified complications
0.766 0.234 0.000
C05 Malignant neoplasm of palate
0.766 0.234 0.000
Q00-Q07 Congenital malformations of the nervous system
0.766 0.234 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.765 0.235 0.000
K51.5 Mucosal proctocolitis
0.000 0.236 0.764
M11 Other crystal arthropathies
0.763 0.237 0.000
Q76 Congenital malformations of spine and bony thorax
0.763 0.237 0.000
C02.2 Ventral surface of tongue
0.763 0.237 0.000
E10.0 With coma
0.762 0.238 0.000
E89.0 Postprocedural hypothyroidism
0.761 0.239 0.000
C10 Malignant neoplasm of oropharynx
0.760 0.239 0.000
E11.0 With coma
0.760 0.240 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.760 0.240 0.000
E11.3 With ophthalmic complications
0.760 0.240 0.000
C95 Leukaemia of unspecified cell type
0.758 0.242 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.758 0.242 0.000
E14.1 With ketoacidosis
0.757 0.243 0.000
E10.8 With unspecified complications
0.757 0.243 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.755 0.245 0.000
B65-B83 Helminthiases
0.755 0.245 0.000
H34.2 Other retinal artery occlusions
0.754 0.246 0.000
M87 Osteonecrosis
0.753 0.247 0.000
B35 Dermatophytosis
0.752 0.248 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.752 0.248 0.000
C18.8 Overlapping lesion of colon
0.750 0.250 0.000
C15 Malignant neoplasm of oesophagus
0.747 0.253 0.000
B44 Aspergillosis
0.746 0.254 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.746 0.254 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.744 0.256 0.000
C03 Malignant neoplasm of gum
0.744 0.256 0.000
H47.1 Papilloedema, unspecified
0.744 0.256 0.000
M24 Other specific joint derangements
0.743 0.257 0.000
C02.4 Lingual tonsil
0.742 0.258 0.000
C23 Malignant neoplasm of gallbladder
0.742 0.258 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.741 0.259 0.000
M12 Other specific arthropathies
0.741 0.259 0.000
M31.6 Other giant cell arteritis
0.740 0.260 0.000
M86.6 Other chronic osteomyelitis
0.740 0.260 0.000
L13 Other bullous disorders
0.740 0.260 0.000
M89.3 Hypertrophy of bone
0.740 0.260 0.000
M70-M79 Other soft tissue disorders
0.739 0.261 0.000
E14.4 With neurological complications
0.739 0.261 0.000
Chapter V Mental and behavioural disorders
0.738 0.262 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.737 0.263 0.000
C83.0 Small cell (diffuse)
0.735 0.265 0.000
D70 Agranulocytosis
0.733 0.267 0.000
C34.8 Overlapping lesion of bronchus and lung
0.732 0.268 0.000
G30.9 Alzheimer's disease, unspecified
0.732 0.268 0.000
M62.0 Diastasis of muscle
0.731 0.269 0.000
C11 Malignant neoplasm of nasopharynx
0.729 0.271 0.000
C80 Malignant neoplasm without specification of site
0.727 0.273 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.726 0.274 0.000
D04.5 Skin of trunk
0.726 0.274 0.000
M86.8 Other osteomyelitis
0.725 0.275 0.000
E14.6 With other specified complications
0.725 0.275 0.000
L52 Erythema nodosum
0.723 0.277 0.000
C07 Malignant neoplasm of parotid gland
0.723 0.277 0.000
E10.6 With other specified complications
0.722 0.278 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.279 0.721
M89.9 Disorder of bone, unspecified
0.721 0.279 0.000
D06.9 Cervix, unspecified
0.720 0.280 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.720 0.280 0.000
H54 Blindness and low vision
0.720 0.280 0.000
B25-B34 Other viral diseases
0.719 0.281 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
M07.38 Other psoriatic arthropathies (Other)
0.717 0.283 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.717 0.283 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.717 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.717 0.283 0.000
C31 Malignant neoplasm of accessory sinuses
0.717 0.283 0.000
C37 Malignant neoplasm of thymus
0.717 0.283 0.000
C33 Malignant neoplasm of trachea
0.717 0.283 0.000
Q65 Congenital deformities of hip
0.717 0.283 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.716 0.284 0.000
C85.0 Lymphosarcoma
0.716 0.284 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.716 0.284 0.000
L44 Other papulosquamous disorders
0.716 0.284 0.000
L41 Parapsoriasis
0.716 0.284 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.716 0.284 0.000
M07.6 Other enteropathic arthropathies
0.716 0.284 0.000
M07.5 Arthropathy in ulcerative colitis
0.716 0.284 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.716 0.284 0.000
M07.2 Psoriatic spondylitis
0.716 0.284 0.000
M07.1 Arthritis mutilans
0.716 0.284 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.716 0.284 0.000
G36 Other acute disseminated demyelination
0.716 0.284 0.000
M62.6 Muscle strain
0.716 0.284 0.000
D04.2 Skin of ear and external auricular canal
0.716 0.284 0.000
G51 Facial nerve disorders
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.715 0.285 0.000
E78.4 Other hyperlipidaemia
0.715 0.285 0.000
E78.6 Lipoprotein deficiency
0.714 0.285 0.000
L89 Decubitus ulcer
0.714 0.286 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.714 0.286 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
L93.0 Discoid lupus erythematosus
0.714 0.286 0.000
B37.4 Candidiasis of other urogenital sites
0.713 0.287 0.000
B37.6 Candidal endocarditis
0.713 0.287 0.000
B37.5 Candidal meningitis
0.713 0.287 0.000
B48 Other mycoses, not elsewhere classified
0.712 0.288 0.000
B47 Mycetoma
0.712 0.288 0.000
B46 Zygomycosis
0.712 0.288 0.000
B45 Cryptococcosis
0.712 0.288 0.000
B43 Chromomycosis and phaeomycotic abscess
0.712 0.288 0.000
B42 Sporotrichosis
0.712 0.288 0.000
B41 Paracoccidioidomycosis
0.712 0.288 0.000
B40 Blastomycosis
0.712 0.288 0.000
B39 Histoplasmosis
0.712 0.288 0.000
B38 Coccidioidomycosis
0.712 0.288 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
B37.7 Candidal septicaemia
0.711 0.289 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.711 0.289 0.000
D61 Other aplastic anaemias
0.710 0.290 0.000
D55-D59 Haemolytic anaemias
0.710 0.290 0.000
B02 Zoster [herpes zoster]
0.709 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.709 0.291 0.000
C86 Other specified types of T/NK-cell lymphoma
0.709 0.291 0.000
C25 Malignant neoplasm of pancreas
0.709 0.291 0.000
E14.2 Withrenal complications
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.708 0.292 0.000
C06.0 Cheek mucosa
0.708 0.292 0.000
B49 Unspecified mycosis
0.708 0.292 0.000
E14.7 With multiple complications
0.708 0.292 0.000
E14.0 With coma
0.708 0.292 0.000
B36 Other superficial mycoses
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
K90.8 Other intestinal malabsorption
0.706 0.294 0.000
E03 Other hypothyroidism
0.705 0.295 0.000
Q78 Other osteochondrodysplasias
0.704 0.296 0.000
L95.9 Vasculitis limited to skin, unspecified
0.703 0.297 0.000
D07.1 Vulva
0.703 0.297 0.000
C91.4 Hairy-cell leukaemia
0.703 0.297 0.000
G40-G47 Episodic and paroxysmal disorders
0.703 0.297 0.000
N04.2 Diffuse membranous glomerulonephritis
0.702 0.298 0.000
E05.8 Other thyrotoxicosis
0.702 0.298 0.000
M60 Myositis
0.702 0.298 0.000
E80.4 Gilbert's syndrome
0.702 0.298 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.702 0.298 0.000
D04.4 Skin of scalp and neck
0.701 0.299 0.000
D86 Sarcoidosis
0.701 0.299 0.000
G58 Other mononeuropathies
0.701 0.299 0.000
C93 Monocytic leukaemia
0.700 0.299 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.700 0.300 0.000
N25-N29 Other disorders of kidney and ureter
0.700 0.300 0.000
N04.1 Focal and segmental glomerular lesions
0.699 0.301 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.699 0.301 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.698 0.302 0.000
C02.8 Overlapping lesion of tongue
0.698 0.302 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.698 0.302 0.000
C02.0 Dorsal surface of tongue
0.698 0.302 0.000
K90.3 Pancreatic steatorrhoea
0.698 0.302 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.698 0.302 0.000
K90.1 Tropical sprue
0.698 0.302 0.000
H47.7 Disorder of visual pathways, unspecified
0.698 0.302 0.000
H47.6 Disorders of visual cortex
0.698 0.302 0.000
H47.5 Disorders of other visual pathways
0.698 0.302 0.000
H47.4 Disorders of optic chiasm
0.698 0.302 0.000
H30.9 Chorioretinal inflammation, unspecified
0.697 0.303 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.304 0.000
D72 Other disorders of white blood cells
0.696 0.304 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.696 0.304 0.000
E78.1 Pure hyperglyceridaemia
0.695 0.305 0.000
C00 Malignant neoplasm of lip
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.694 0.306 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.694 0.306 0.000
D73 Diseases of spleen
0.693 0.307 0.000
E16.1 Other hypoglycaemia
0.693 0.307 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.692 0.308 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.692 0.308 0.000
M35.5 Multifocal fibrosclerosis
0.692 0.308 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.692 0.308 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.689 0.311 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.689 0.311 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.689 0.311 0.000
C84.3 Lymphoepithelioid lymphoma
0.689 0.311 0.000
C84.2 T-zone lymphoma
0.689 0.311 0.000
C84.1 Sezary's diease
0.689 0.311 0.000
Q74 Other congenital malformations of limb(s)
0.689 0.311 0.000
N11.1 Chronic obstructive pyelonephritis
0.689 0.311 0.000
C81.2 Mixed cellularity
0.688 0.312 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.688 0.312 0.000
L94.0 Localised scleroderma [morphea]
0.688 0.312 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.687 0.313 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.687 0.313 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.687 0.313 0.000
M61 Calcification and ossification of muscle
0.687 0.313 0.000
K50.0 Crohn's disease of small intestine
0.000 0.314 0.686
K72.9 Hepatic failure, unspecified
0.686 0.314 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.686 0.314 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.685 0.315 0.000
H43-H45 Disorders of vitreous body and globe
0.684 0.316 0.000
M90 Osteopathies in diseases classified elsewhere
0.684 0.316 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.683 0.316 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.682 0.317 0.000
C76.0 Head, face and neck
0.681 0.319 0.000
B37.3 Candidiasis of vulva and vagina
0.681 0.319 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.680 0.319 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.679 0.321 0.000
D04.1 Skin of eyelid, including canthus
0.679 0.321 0.000
M35.1 Other overlap syndromes
0.679 0.321 0.000
E10.5 With peripheral circulatory complications
0.678 0.321 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.678 0.322 0.000
C91.7 Other lymphoid leukaemia
0.678 0.322 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.678 0.322 0.000
C91.5 Adult T-cell leukaemia
0.678 0.322 0.000
C91.3 Prolymphocytic leukaemia
0.678 0.322 0.000
C91.2 Subacute lymphocytic leukaemia
0.678 0.322 0.000
N05.1 Focal and segmental glomerular lesions
0.678 0.322 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.678 0.322 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.678 0.322 0.000
N06 Isolated proteinuria with specified morphological lesion
0.678 0.322 0.000
N01 Rapidly progressive nephritic syndrome
0.678 0.322 0.000
N00 Acute nephritic syndrome
0.678 0.322 0.000
C18.5 Splenic flexure
0.677 0.323 0.000
Q60-Q64 Congenital malformations of the urinary system
0.677 0.323 0.000
E07.8 Other specified disorders of thyroid
0.676 0.324 0.000
M31.1 Thrombotic microangiopathy
0.675 0.325 0.000
L40.8 Other psoriasis
0.674 0.326 0.000
D62 Acute posthaemorrhagic anaemia
0.672 0.328 0.000
L42 Pityriasis rosea
0.672 0.328 0.000
L94.2 Calcinosis cutis
0.670 0.329 0.000
M93 Other osteochondropathies
0.670 0.330 0.000
M21 Other acquired deformities of limbs
0.669 0.331 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.669 0.331 0.000
H34.9 Retinal vascular occlusion, unspecified
0.669 0.331 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.669 0.331 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.669 0.331 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.669 0.331 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.669 0.331 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.669 0.331 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.668 0.332 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.668 0.332 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.667 0.333 0.000
E40-E46 Malnutrition
0.666 0.334 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.666 0.334 0.000
B02.9 Zoster without complication
0.666 0.334 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.665 0.335 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.665 0.335 0.000
M86.3 Chronic multifocal osteomyelitis
0.665 0.335 0.000
M86.2 Subacute osteomyelitis
0.665 0.335 0.000
M86.1 Other acute osteomyelitis
0.665 0.335 0.000
M86.0 Acute haematogenous osteomyelitis
0.665 0.335 0.000
M62.9 Disorder of muscle, unspecified
0.664 0.336 0.000
M62.4 Contracture of muscle
0.664 0.336 0.000
M62.3 Immobility syndrome (paraplegic)
0.664 0.336 0.000
M62.2 Ischaemic infarction of muscle
0.664 0.336 0.000
E11.8 With unspecified complications
0.664 0.336 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.664 0.336 0.000
L91 Hypertrophic disorders of skin
0.663 0.337 0.000
N13.4 Hydroureter
0.662 0.338 0.000
C60-C63 Malignant neoplasms of male genital organs
0.659 0.339 0.002
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.660 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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