TreeWAS – Variant ID: rs35822625

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O34.2 Maternal care due to uterine scar from previous surgery	0.051	0.949	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.032	0.968	0.000
O34.0 Maternal care for congenital malformation of uterus	0.027	0.973	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.024	0.976	0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.000	0.976	0.024
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.023	0.977	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.023	0.977	0.000
O34.6 Maternal care for abnormality of vagina	0.023	0.977	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.023	0.977	0.000
O34.4 Maternal care for other abnormalities of cervix	0.023	0.977	0.000
O34.3 Maternal care for cervical incompetence	0.023	0.977	0.000
O34.1 Maternal care for tumour of corpus uteri	0.021	0.978	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.013	0.987	0.000
O47.9 False labour, unspecified	0.012	0.988	0.000
O41 Other disorders of amniotic fluid and membranes	0.012	0.988	0.000
O47 False labour	0.012	0.988	0.000
O43 Placental disorders	0.011	0.989	0.000
O40 Polyhydramnios	0.011	0.989	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.010	0.990	0.000
O45 Premature separation of placenta [abruptio placentae]	0.010	0.990	0.000
O41.0 Oligohydramnios	0.010	0.990	0.000
O33 Maternal care for known or suspected disproportion	0.010	0.990	0.000
O31 Complications specific to multiple gestation	0.010	0.990	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.009	0.991	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.009	0.991	0.000
C15-C26 Malignant neoplasms of digestive organs	0.009	0.991	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.009	0.991	0.000
C20 Malignant neoplasm of rectum	0.009	0.991	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.009	0.991	0.000
O44 Placenta praevia	0.009	0.991	0.000
O48 Prolonged pregnancy	0.009	0.991	0.000
O43.1 Malformation of placenta	0.009	0.991	0.000
O43.8 Other placental disorders	0.009	0.991	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.009	0.991	0.000
O41.1 Infection of amniotic sac and membranes	0.009	0.991	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.991	0.009
C19 Malignant neoplasm of rectosigmoid junction	0.008	0.991	0.000
O30 Multiple gestation	0.008	0.992	0.000
O43.9 Placental disorder, unspecified	0.008	0.992	0.000
O43.2 Morbidly adherent placenta	0.008	0.992	0.000
O43.0 Placental transfusion syndromes	0.008	0.992	0.000
O47.0 False labour before 37 completed weeks of gestation	0.008	0.992	0.000
C23 Malignant neoplasm of gallbladder	0.008	0.992	0.000
C22.1 Intrahepatic bile duct carcinoma	0.008	0.992	0.000
H66.9 Otitis media, unspecified	0.008	0.992	0.000
R31 Unspecified haematuria	0.000	0.992	0.008
C22.0 Liver cell carcinoma	0.008	0.992	0.000
C17 Malignant neoplasm of small intestine	0.008	0.992	0.000
O45.9 Premature separation of placenta, unspecified	0.008	0.992	0.000
C15 Malignant neoplasm of oesophagus	0.008	0.992	0.000
C25 Malignant neoplasm of pancreas	0.008	0.992	0.000
C22.9 Liver, unspecified	0.007	0.992	0.000
O32.1 Maternal care for breech presentation	0.008	0.992	0.000
O45.8 Other premature separation of placenta	0.007	0.992	0.000
O45.0 Premature separation of placenta with coagulation defect	0.007	0.992	0.000
C16 Malignant neoplasm of stomach	0.007	0.993	0.000
O31.8 Other complications specific to multiple gestation	0.007	0.993	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.007	0.993	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.007	0.993	0.000
O31.0 Papyraceous foetus	0.007	0.993	0.000
O33.9 Maternal care for disproportion, unspecified	0.007	0.993	0.000
O33.8 Maternal care for disproportion of other origin	0.007	0.993	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.007	0.993	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.007	0.993	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.007	0.993	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.007	0.993	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.007	0.993	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.007	0.993	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.007	0.993	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.007	0.993	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.007	0.993	0.000
O32.2 Maternal care for transverse and oblique lie	0.007	0.993	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.007	0.993	0.000
H66 Suppurative and unspecified otitis media	0.007	0.993	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.007	0.993	0.000
O32.8 Maternal care for other malpresentation of foetus	0.007	0.993	0.000
O32.6 Maternal care for compound presentation	0.007	0.993	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.007	0.993	0.000
O32.4 Maternal care for high head at term	0.007	0.993	0.000
O32.3 Maternal care for face, brow and chin presentation	0.007	0.993	0.000
C21 Malignant neoplasm of anus and anal canal	0.007	0.993	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.007	0.993	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.007	0.993	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.007	0.993	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.007	0.993	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.007	0.993	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.007	0.993	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.007	0.993	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.007	0.993	0.000
H66.3 Other chronic suppurative otitis media	0.007	0.993	0.000
O46.8 Other antepartum haemorrhage	0.007	0.993	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.007	0.993	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.007	0.993	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.007	0.993	0.000
C22.7 Other specified carcinomas of liver	0.007	0.993	0.000
C22.4 Other sarcomas of liver	0.007	0.993	0.000
C22.3 Angiosarcoma of liver	0.007	0.993	0.000
C22.2 Hepatoblastoma	0.007	0.993	0.000
O44.1 Placenta praevia with haemorrhage	0.007	0.993	0.000
C15.9 Oesophagus, unspecified	0.007	0.993	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.006	0.993	0.000
C25.1 Body of pancreas	0.006	0.993	0.000
C17.0 Duodenum	0.006	0.993	0.000
O30.9 Multiple gestation, unspecified	0.006	0.994	0.000
O30.8 Other multiple gestation	0.006	0.994	0.000
O30.2 Quadruplet pregnancy	0.006	0.994	0.000
O30.1 Triplet pregnancy	0.006	0.994	0.000
C25.0 Head of pancreas	0.006	0.994	0.000
O46.9 Antepartum haemorrhage, unspecified	0.006	0.994	0.000
C17.9 Small intestine, unspecified	0.006	0.994	0.000
C16.9 Stomach, unspecified	0.006	0.994	0.000
C25.2 Tail of pancreas	0.006	0.994	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.006	0.994	0.000
C17.8 Overlapping lesion of small intestine	0.006	0.994	0.000
C17.3 Meckel's diverticulum	0.006	0.994	0.000
C17.1 Jejunum	0.006	0.994	0.000
C15.4 Middle third of oesophagus	0.006	0.994	0.000
C16.5 Lesser curvature of stomach, unspecified	0.006	0.994	0.000
C15.8 Overlapping lesion of oesophagus	0.006	0.994	0.000
C15.3 Upper third of oesophagus	0.006	0.994	0.000
C15.2 Abdominal part of oesophagus	0.006	0.994	0.000
C15.1 Thoracic part of oesophagus	0.006	0.994	0.000
C15.0 Cervical part of oesophagus	0.006	0.994	0.000
C17.2 Ileum	0.006	0.994	0.000
O32.0 Maternal care for unstable lie	0.006	0.994	0.000
C25.8 Overlapping lesion of pancreas	0.006	0.994	0.000
C25.7 Other parts of pancreas	0.006	0.994	0.000
C25.4 Endocrine pancreas	0.006	0.994	0.000
C25.3 Pancreatic duct	0.006	0.994	0.000
C26.0 Intestinal tract, part unspecified	0.006	0.994	0.000
H02.0 Entropion and trichiasis of eyelid	0.006	0.994	0.000
C24.0 Extrahepatic bile duct	0.006	0.994	0.000
C21.1 Anal canal	0.006	0.994	0.000
C16.8 Overlapping lesion of stomach	0.005	0.994	0.000
C16.6 Greater curvature of stomach, unspecified	0.005	0.994	0.000
C16.4 Pylorus	0.005	0.994	0.000
C16.3 Pyloric antrum	0.005	0.994	0.000
C16.2 Body of stomach	0.005	0.994	0.000
C16.1 Fundus of stomach	0.005	0.994	0.000
O36 Maternal care for other known or suspected foetal problems	0.006	0.994	0.000
C15.5 Lower third of oesophagus	0.005	0.994	0.000
C26.9 Ill-defined sites within the digestive system	0.005	0.995	0.000
C26.8 Overlapping lesion of digestive system	0.005	0.995	0.000
C26.1 Spleen	0.005	0.995	0.000
C24.9 Biliary tract, unspecified	0.005	0.995	0.000
C24.8 Overlapping lesion of biliary tract	0.005	0.995	0.000
C24.1 Ampulla of Vater	0.005	0.995	0.000
H66.4 Suppurative otitis media, unspecified	0.005	0.995	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.005	0.995	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.005	0.995	0.000
H66.0 Acute suppurative otitis media	0.005	0.995	0.000
C16.0 Cardia	0.005	0.995	0.000
K21 Gastro-oesophageal reflux disease	0.000	0.995	0.005
C21.8 Overlapping lesion of rectum, anus and anal canal	0.005	0.995	0.000
C21.2 Cloacogenic zone	0.005	0.995	0.000
O72.0 Third-stage haemorrhage	0.005	0.995	0.000
C21.0 Anus, unspecified	0.005	0.995	0.000
H65-H75 Diseases of middle ear and mastoid	0.005	0.995	0.000
H71 Cholesteatoma of middle ear	0.005	0.995	0.000
O30.0 Twin pregnancy	0.005	0.995	0.000
C25.9 Pancreas, unspecified	0.005	0.995	0.000
O72 Postpartum haemorrhage	0.005	0.995	0.000
H70 Mastoiditis and related conditions	0.004	0.995	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.004	0.995	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.004	0.996	0.000
O42 Premature rupture of membranes	0.004	0.996	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.004	0.996	0.000
O36.4 Maternal care for intra-uterine death	0.004	0.996	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.004	0.996	0.000
O36.2 Maternal care for hydrops foetalis	0.004	0.996	0.000
O36.1 Maternal care for other isoimmunisation	0.004	0.996	0.000
H70.9 Mastoiditis, unspecified	0.004	0.996	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.004	0.996	0.000
H72 Perforation of tympanic membrane	0.004	0.996	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H68 Eustachian salpingitis and obstruction	0.004	0.996	0.000
H67 Otitis media in diseases classified elsewhere	0.004	0.996	0.000
O36.6 Maternal care for excessive foetal growth	0.004	0.996	0.000
O36.5 Maternal care for poor foetal growth	0.003	0.996	0.000
H74 Other disorders of middle ear and mastoid	0.004	0.996	0.000
H73 Other disorders of tympanic membrane	0.004	0.996	0.000
O36.9 Maternal care for foetal problem, unspecified	0.003	0.996	0.000
O72.3 Postpartum coagulation defects	0.003	0.996	0.000
O64.1 Obstructed labour due to breech presentation	0.004	0.996	0.000
O72.1 Other immediate postpartum haemorrhage	0.004	0.996	0.000
E11.5 With peripheral circulatory complications	0.004	0.996	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.996	0.000
H70.2 Petrositis	0.003	0.996	0.000
H70.1 Chronic mastoiditis	0.003	0.996	0.000
H70.0 Acute mastoiditis	0.003	0.996	0.000
H69 Other disorders of Eustachian tube	0.003	0.996	0.000
F43.2 Adjustment disorders	0.003	0.997	0.000
R33 Retention of urine	0.000	0.997	0.003
O42.2 Premature rupture of membranes, labour delayed by therapy	0.003	0.997	0.000
F43.0 Acute stress reaction	0.003	0.997	0.000
F43 Reaction to severe stress, and adjustment disorders	0.003	0.997	0.000
F43.9 Reaction to severe stress, unspecified	0.003	0.997	0.000
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.003	0.997	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.003	0.997	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.003	0.997	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.003	0.997	0.000
H68.1 Obstruction of Eustachian tube	0.003	0.997	0.000
H68.0 Eustachian salpingitis	0.003	0.997	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
O60-O75 Complications of labour and delivery	0.003	0.997	0.000
F43.1 Posttraumatic stress disorder	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.003	0.997	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.003	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.997	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.003	0.997	0.000
H74.1 Adhesive middle ear disease	0.003	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
R30 Pain associated with micturition	0.000	0.997	0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.997	0.003
H69.8 Other specified disorders of Eustachian tube	0.003	0.997	0.000
H69.0 Patulous Eustachian tube	0.003	0.997	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.003	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.997	0.000
I73.0 Raynaud's syndrome	0.000	0.997	0.003
R30.9 Painful micturition, unspecified	0.000	0.997	0.003
H74.0 Tympanosclerosis	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
O42.9 Premature rupture of membranes, unspecified	0.002	0.997	0.000
O82.0 Delivery by elective Caesarean section	0.003	0.997	0.000
F43.8 Other reactions to severe stress	0.003	0.997	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.997	0.000
O71 Other obstetric trauma	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.997	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.002	0.997	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.002	0.997	0.000
O64.5 Obstructed labour due to compound presentation	0.002	0.997	0.000
O64.4 Obstructed labour due to shoulder presentation	0.002	0.997	0.000
O64.3 Obstructed labour due to brow presentation	0.002	0.997	0.000
O64.2 Obstructed labour due to face presentation	0.002	0.997	0.000
R30.0 Dysuria	0.000	0.997	0.003
O75 Other complications of labour and delivery, not elsewhere classified	0.003	0.997	0.000
R30-R39 Symptoms and signs involving the urinary system	0.000	0.997	0.003
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.997	0.000
J39.2 Other diseases of pharynx	0.003	0.997	0.000
O82 Single delivery by Caesarean section	0.002	0.997	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.997	0.000
O73 Retained placenta and membranes, without haemorrhage	0.002	0.997	0.000
O85-O92 Complications predominantly related to the puerperium	0.002	0.997	0.000
O62 Abnormalities of forces of labour	0.002	0.998	0.000
O80-O84 Delivery	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
O74 Complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.002	0.998	0.000
O60 Preterm delivery	0.002	0.998	0.000
E11.2 With renal complications	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
O71.7 Obstetric haematoma of pelvis	0.002	0.998	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.002	0.998	0.000
O62.0 Primary inadequate contractions	0.002	0.998	0.000
R30.1 Vesical tenesmus	0.000	0.998	0.002
O61 Failed induction of labour	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
O66 Other obstructed labour	0.002	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
O71.8 Other specified obstetric trauma	0.002	0.998	0.000
O90 Complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
O71.4 Obstetric high vaginal laceration alone	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.000	0.998	0.002
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
O71.9 Obstetric trauma, unspecified	0.002	0.998	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.002	0.998	0.000
O71.5 Other obstetric injury to pelvic organs	0.002	0.998	0.000
O71.3 Obstetric laceration of cervix	0.002	0.998	0.000
O71.2 Postpartum inversion of uterus	0.002	0.998	0.000
O71.1 Rupture of uterus during labour	0.002	0.998	0.000
O71.0 Rupture of uterus before onset of labour	0.002	0.998	0.000
O62.1 Secondary uterine inertia	0.002	0.998	0.000
E11 Non-insulin-dependent diabetes mellitus	0.002	0.998	0.000
O75.9 Complication of labour and delivery, unspecified	0.002	0.998	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.002	0.998	0.000
O75.4 Other complications of obstetric surgery and procedures	0.002	0.998	0.000
O75.3 Other infection during labour	0.002	0.998	0.000
O75.1 Shock during or following labour and delivery	0.002	0.998	0.000
R36 Urethral discharge	0.000	0.998	0.002
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
O69 Labour and delivery complicated by umbilical cord complications	0.002	0.998	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.002	0.998	0.000
R12 Heartburn	0.000	0.998	0.002
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
O62.3 Precipitate labour	0.002	0.998	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.002	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.001	0.998	0.001
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.002	0.998	0.000
O91 Infections of breast associated with childbirth	0.002	0.998	0.000
O89 Complications of anaesthesia during the puerperium	0.002	0.998	0.000
O88 Obstetric embolism	0.002	0.998	0.000
O85 Puerperal sepsis	0.002	0.998	0.000
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
O84 Multiple delivery	0.002	0.998	0.000
O83 Other assisted single delivery	0.002	0.998	0.000
O87 Venous complications in the puerperium	0.002	0.998	0.000
R34 Anuria and oliguria	0.000	0.998	0.002
I73.9 Peripheral vascular disease, unspecified	0.000	0.998	0.002
O62.9 Abnormality of forces of labour, unspecified	0.002	0.998	0.000
O62.8 Other abnormalities of forces of labour	0.002	0.998	0.000
O60.3 Preterm delivery without spontaneous labour	0.002	0.998	0.000
O60.2 Preterm spontaneous labour with term delivery	0.002	0.998	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.002	0.998	0.000
O60.0 Preterm labour without delivery	0.002	0.998	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.002	0.998	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.002	0.998	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.002	0.998	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.002	0.998	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.002	0.998	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.002	0.998	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.002	0.998	0.000
O65.0 Obstructed labour due to deformed pelvis	0.002	0.998	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.002	0.998	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.002	0.998	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.002	0.998	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.002	0.998	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.002	0.998	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.002	0.998	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
O86 Other puerperal infections	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
H95.1 Other disorders following mastoidectomy	0.002	0.998	0.000
E11.4 With neurological complications	0.002	0.998	0.000
E11.0 With coma	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
E11.6 With other specified complications	0.002	0.998	0.000
M47.9 Spondylosis, unspecified	0.002	0.998	0.000
O67.8 Other intrapartum haemorrhage	0.002	0.998	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.002	0.998	0.000
O61.9 Failed induction of labour, unspecified	0.002	0.998	0.000
O61.8 Other failed induction of labour	0.002	0.998	0.000
O61.1 Failed instrumental induction of labour	0.002	0.998	0.000
O66.9 Obstructed labour, unspecified	0.002	0.998	0.000
O66.8 Other specified obstructed labour	0.002	0.998	0.000
O66.4 Failed trial of labour, unspecified	0.002	0.998	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.002	0.998	0.000
O66.2 Obstructed labour due to unusually large foetus	0.002	0.998	0.000
O66.1 Obstructed labour due to locked twins	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
G99.2 Myelopathy in diseases classified elsewhere	0.002	0.998	0.000
S30.0 Contusion of lower back and pelvis	0.002	0.998	0.000
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.000	0.998	0.002
O69.8 Labour and delivery complicated by other cord complications	0.002	0.998	0.000
O90.9 Complication of the puerperium, unspecified	0.002	0.998	0.000
O90.5 Postpartum thyroiditis	0.002	0.998	0.000
O90.4 Postpartum acute renal failure	0.002	0.998	0.000
O90.3 Cardiomyopathy in the puerperium	0.002	0.998	0.000
O90.2 Haematoma of obstetric wound	0.002	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.002	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
E23.0 Hypopituitarism	0.000	0.998	0.002
I73.8 Other specified peripheral vascular diseases	0.000	0.998	0.002
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.998	0.002
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
I70 Atherosclerosis	0.000	0.998	0.002
E11.7 With multiple complications	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.002	0.998	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.998	0.002
E11.8 With unspecified complications	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
E11.1 With ketoacidosis	0.002	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.002	0.998	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.002	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.002	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.002	0.998	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.002	0.998	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.998	0.002
I25.1 Atherosclerotic heart disease	0.000	0.998	0.002
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
O88.8 Other obstetric embolism	0.001	0.998	0.000
O88.3 Obstetric pyaemic and septic embolism	0.001	0.998	0.000
O88.2 Obstetric blood-clot embolism	0.001	0.998	0.000
O88.1 Amniotic fluid embolism	0.001	0.998	0.000
O88.0 Obstetric air embolism	0.001	0.998	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.001	0.998	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.001	0.998	0.000
O89.6 Failed or difficult intubation during the puerperium	0.001	0.998	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.001	0.998	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.001	0.998	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.001	0.998	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.001	0.998	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.001	0.998	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.001	0.998	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.001	0.998	0.000
O91.1 Abscess of breast associated with childbirth	0.001	0.998	0.000
O91.0 Infection of nipple associated with childbirth	0.001	0.998	0.000
O92.7 Other and unspecified disorders of lactation	0.001	0.998	0.000
O92.6 Galactorrhoea	0.001	0.998	0.000
O92.5 Suppressed lactation	0.001	0.998	0.000
O92.4 Hypogalactia	0.001	0.998	0.000
O92.3 Agalactia	0.001	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.001	0.998	0.000
O92.1 Cracked nipple associated with childbirth	0.001	0.998	0.000
O92.0 Retracted nipple associated with childbirth	0.001	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
O83.9 Assisted single delivery, unspecified	0.001	0.998	0.000
O83.8 Other specified assisted single delivery	0.001	0.998	0.000
O83.4 Destructive operation for delivery	0.001	0.998	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.001	0.998	0.000
O83.2 Other manipulation-assisted delivery	0.001	0.998	0.000
O83.1 Other assisted breech delivery	0.001	0.998	0.000
O83.0 Breech extraction	0.001	0.998	0.000
O84.9 Multiple delivery, unspecified	0.001	0.998	0.000
O84.8 Other multiple delivery	0.001	0.998	0.000
O84.2 Multiple delivery, all by Caesarean section	0.001	0.998	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.001	0.998	0.000
O84.0 Multiple delivery, all spontaneous	0.001	0.998	0.000
O87.9 Venous complication in the puerperium, unspecified	0.001	0.998	0.000
O87.8 Other venous complications in the puerperium	0.001	0.998	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.001	0.998	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.001	0.998	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.001	0.998	0.000
R06.5 Mouth breathing	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.002	0.998	0.000
O22 Venous complications in pregnancy	0.002	0.998	0.000
O25 Malnutrition in pregnancy	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.998	0.002
I70.0 Atherosclerosis of aorta	0.000	0.998	0.002
O81.5 Delivery by combination of forceps and vacuum extractor	0.001	0.998	0.000
O81.3 Other and unspecified forceps delivery	0.001	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.001	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.001	0.998	0.000
O81.0 Low forceps delivery	0.001	0.998	0.000
O86.8 Other specified puerperal infections	0.001	0.998	0.000
O86.4 Pyrexia of unknown origin following delivery	0.001	0.998	0.000
O86.3 Other genito-urinary tract infections following delivery	0.001	0.998	0.000
O86.2 Urinary tract infection following delivery	0.001	0.998	0.000
O86.1 Other infection of genital tract following delivery	0.001	0.998	0.000
O87.2 Haemorrhoids in the puerperium	0.001	0.998	0.000
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.002	0.998	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.001	0.998	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
M84.0 Malunion of fracture	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.000	0.998	0.001
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.998	0.001
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.001
O24.9 Diabetes mellitus in pregnancy, unspecified	0.001	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.001	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.001	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.001	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.001	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations