TreeWAS – Variant ID: rs35971989

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z08 Follow-up examination after treatment for malignant neoplasm	0.000	0.912	0.088
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.912	0.088
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.914	0.086
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.000	0.917	0.083
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.000	0.922	0.078
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.922	0.078
M25.51 Pain in joint (Shoulder region)	0.065	0.935	0.000
M25.56 Pain in joint (Lower leg)	0.064	0.936	0.000
M25.5 Pain in joint	0.064	0.936	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.060	0.940	0.000
M25.57 Pain in joint (Ankle and foot)	0.056	0.944	0.000
M25.58 Pain in joint (Other)	0.052	0.948	0.000
M25.59 Pain in joint (Site unspecified)	0.050	0.949	0.000
M25.53 Pain in joint (Forearm)	0.049	0.951	0.000
M25.54 Pain in joint (Hand)	0.044	0.956	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.963	0.037
M25.52 Pain in joint (Upper arm)	0.034	0.966	0.000
M25.50 Pain in joint (Multiple sites)	0.018	0.982	0.000
R53 Malaise and fatigue	0.000	0.982	0.018
D68.9 Coagulation defect, unspecified	0.000	0.985	0.015
D68 Other coagulation defects	0.000	0.985	0.015
D68.8 Other specified coagulation defects	0.000	0.985	0.015
D68.5 Primary Thrombophilia	0.000	0.987	0.013
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.987	0.013
D68.6 Other Thrombophilia	0.000	0.988	0.012
D68.0 Von Willebrand's disease	0.000	0.988	0.012
D68.4 Acquired coagulation factor deficiency	0.000	0.989	0.011
D68.1 Hereditary factor XI deficiency	0.000	0.989	0.011
B37.0 Candidal stomatitis	0.000	0.990	0.010
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.990	0.010
B37.8 Candidiasis of other sites	0.000	0.991	0.009
E10.9 Without complications	0.000	0.991	0.009
B37 Candidiasis	0.000	0.991	0.009
T39.1 4-Aminophenol derivatives	0.009	0.991	0.000
B37.9 Candidiasis, unspecified	0.000	0.992	0.008
D68.2 Hereditary deficiency of other clotting factors	0.000	0.992	0.008
D69 Purpura and other haemorrhagic conditions	0.000	0.992	0.008
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.992	0.008
D66 Hereditary factor VIII deficiency	0.000	0.992	0.008
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.993	0.007
K80.1 Calculus of gallbladder with other cholecystitis	0.007	0.993	0.000
N94.1 Dyspareunia	0.000	0.993	0.007
D67 Hereditary factor IX deficiency	0.000	0.993	0.007
D69.5 Secondary thrombocytopenia	0.000	0.993	0.007
B37.7 Candidal septicaemia	0.000	0.993	0.006
B37.6 Candidal endocarditis	0.000	0.993	0.006
B37.5 Candidal meningitis	0.000	0.993	0.006
B37.1 Pulmonary candidiasis	0.000	0.994	0.006
D69.8 Other specified haemorrhagic conditions	0.000	0.994	0.006
D69.2 Other nonthrombocytopenic purpura	0.000	0.994	0.006
D69.1 Qualitative platelet defects	0.000	0.994	0.006
B37.2 Candidiasis of skin and nail	0.000	0.994	0.006
M25 Other joint disorders, not elsewhere classified	0.006	0.994	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.994	0.005
D69.4 Other primary thrombocytopenia	0.000	0.994	0.005
D69.0 Allergic purpura	0.000	0.995	0.005
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
B37.4 Candidiasis of other urogenital sites	0.000	0.995	0.005
B37.3 Candidiasis of vulva and vagina	0.000	0.995	0.005
E53.8 Deficiency of other specified B group vitamins	0.005	0.995	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.005	0.995	0.000
M25.0 Haemarthrosis	0.005	0.995	0.000
Y44.2 Anticoagulants	0.000	0.995	0.005
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.995	0.000
M25.3 Other instability of joint	0.004	0.995	0.000
M25.2 Flail joint	0.004	0.996	0.000
M25.1 Fistula of joint	0.004	0.996	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M25.06 Haemarthrosis (Lower leg)	0.004	0.996	0.000
M25.4 Effusion of joint	0.004	0.996	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.004	0.996	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.996	0.004
M25.34 Other instability of joint (Hand)	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.996	0.004
E10 Insulin-dependent diabetes mellitus	0.000	0.996	0.004
M25.09 Haemarthrosis (Site unspecified)	0.004	0.996	0.000
M25.08 Haemarthrosis (Other)	0.004	0.996	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.004	0.996	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.004	0.996	0.000
M25.04 Haemarthrosis (Hand)	0.004	0.996	0.000
M25.03 Haemarthrosis (Forearm)	0.004	0.996	0.000
M25.02 Haemarthrosis (Upper arm)	0.004	0.996	0.000
M25.01 Haemarthrosis (Shoulder region)	0.004	0.996	0.000
M25.00 Haemarthrosis (Multiple sites)	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.996	0.000
T44.0 Anticholinesterase agents	0.003	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.996	0.000
T39.2 Pyrazolone derivatives	0.003	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
M25.31 Other instability of joint (Shoulder region)	0.003	0.996	0.000
M25.43 Effusion of joint (Forearm)	0.003	0.996	0.000
M25.42 Effusion of joint (Upper arm)	0.003	0.996	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.996	0.004
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.996	0.000
M25.39 Other instability of joint (Site unspecified)	0.003	0.996	0.000
M25.38 Other instability of joint (Other)	0.003	0.996	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.003	0.996	0.000
M25.33 Other instability of joint (Forearm)	0.003	0.996	0.000
M25.32 Other instability of joint (Upper arm)	0.003	0.996	0.000
M25.30 Other instability of joint (Multiple sites)	0.003	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.996	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
M25.37 Other instability of joint (Ankle and foot)	0.003	0.997	0.000
M25.36 Other instability of joint (Lower leg)	0.003	0.997	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.003	0.997	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.997	0.003
E10.4 With neurological complications	0.000	0.997	0.003
M25.19 Fistula of joint (Site unspecified)	0.003	0.997	0.000
M25.18 Fistula of joint (Other)	0.003	0.997	0.000
M25.17 Fistula of joint (Ankle and foot)	0.003	0.997	0.000
M25.16 Fistula of joint (Lower leg)	0.003	0.997	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.003	0.997	0.000
M25.14 Fistula of joint (Hand)	0.003	0.997	0.000
M25.13 Fistula of joint (Forearm)	0.003	0.997	0.000
M25.12 Fistula of joint (Upper arm)	0.003	0.997	0.000
M25.11 Fistula of joint (Shoulder region)	0.003	0.997	0.000
M25.10 Fistula of joint (Multiple sites)	0.003	0.997	0.000
M25.29 Flail joint (Site unspecified)	0.003	0.997	0.000
M25.28 Flail joint (Other)	0.003	0.997	0.000
M25.27 Flail joint (Ankle and foot)	0.003	0.997	0.000
M25.26 Flail joint (Lower leg)	0.003	0.997	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.003	0.997	0.000
M25.24 Flail joint (Hand)	0.003	0.997	0.000
M25.23 Flail joint (Forearm)	0.003	0.997	0.000
M25.22 Flail joint (Upper arm)	0.003	0.997	0.000
M25.21 Flail joint (Shoulder region)	0.003	0.997	0.000
M25.20 Flail joint (Multiple sites)	0.003	0.997	0.000
M25.40 Effusion of joint (Multiple sites)	0.003	0.997	0.000
M25.9 Joint disorder, unspecified	0.003	0.997	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.997	0.003
E10.8 With unspecified complications	0.000	0.997	0.003
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
E10.1 With ketoacidosis	0.000	0.997	0.003
M25.49 Effusion of joint (Site unspecified)	0.003	0.997	0.000
M25.48 Effusion of joint (Other)	0.003	0.997	0.000
M25.41 Effusion of joint (Shoulder region)	0.003	0.997	0.000
X23.9 Unspecified place	0.000	0.997	0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
M25.44 Effusion of joint (Hand)	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.997	0.003
M25.47 Effusion of joint (Ankle and foot)	0.003	0.997	0.000
E10.6 With other specified complications	0.000	0.997	0.003
E10.0 With coma	0.000	0.997	0.003
T40.6 Other and unspecified narcotics	0.003	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.997	0.003
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.003	0.997	0.000
E10.7 With multiple complications	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
S82.2 Fracture of shaft of tibia	0.000	0.997	0.003
T40.4 Other synthetic narcotics	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
N70.1 Chronic salpingitis and oophoritis	0.003	0.997	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.997	0.000
T40.8 Lysergide [LSD]	0.003	0.997	0.000
T40.7 Cannabis (derivatives)	0.003	0.997	0.000
T40.5 Cocaine	0.003	0.997	0.000
T40.3 Methadone	0.003	0.997	0.000
T40.1 Heroin	0.003	0.997	0.000
T40.0 Opium	0.003	0.997	0.000
E10.2 With renal complications	0.000	0.997	0.003
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.997	0.000
E53 Deficiency of other B group vitamins	0.003	0.997	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.002	0.997	0.000
M25.98 Joint disorder, unspecified (Other)	0.002	0.997	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.002	0.997	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.002	0.997	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.002	0.997	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.997	0.003
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.997	0.003
K92.9 Disease of digestive system, unspecified	0.003	0.997	0.000
M25.94 Joint disorder, unspecified (Hand)	0.002	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
T47.7 Emetics	0.002	0.997	0.000
T47.5 Digestants	0.002	0.997	0.000
T47.4 Other laxatives	0.002	0.997	0.000
T47.3 Saline and osmotic laxatives	0.002	0.997	0.000
T47.2 Stimulant laxatives	0.002	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.997	0.000
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
T41.5 Therapeutic gases	0.002	0.997	0.000
T41.4 Anaesthetic, unspecified	0.002	0.997	0.000
T41.3 Local anaesthetics	0.002	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.997	0.000
T41.1 Intravenous anaesthetics	0.002	0.997	0.000
T41.0 Inhaled anaesthetics	0.002	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
T48.5 Anti-common-cold drugs	0.002	0.997	0.000
T48.4 Expectorants	0.002	0.997	0.000
T48.3 Antitussives	0.002	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.997	0.000
T48.0 Oxytocic drugs	0.002	0.997	0.000
T49.9 Topical agent, unspecified	0.002	0.997	0.000
T49.8 Other topical agents	0.002	0.997	0.000
T49.7 Dental drugs, topically applied	0.002	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.997	0.000
T49.2 Local astringents and local detergents	0.002	0.997	0.000
T49.1 Antipruritics	0.002	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.997	0.000
T50.8 Diagnostic agents	0.002	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.997	0.000
T50.5 Appetite depressants	0.002	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.997	0.000
M47.2 Other spondylosis with radiculopathy	0.003	0.997	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
H53.2 Diplopia	0.002	0.998	0.000
H44.2 Degenerative myopia	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
M25.8 Other specified joint disorders	0.002	0.998	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
K29.5 Chronic gastritis, unspecified	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Z98.0 Intestinal bypass and anastomosis status	0.000	0.998	0.002
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.998	0.002
R26.8 Other and unspecified abnormalities of gait and mobility	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.002	0.998	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.000	0.998	0.002
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.002	0.998	0.000
E53.0 Riboflavin deficiency	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.000	0.998	0.002
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.998	0.002
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
Q66.2 Metatarsus varus	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
T36.0 Penicillins	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.002	0.998	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.002	0.998	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.000	0.998	0.002
Z09.8 Follow-up examination after other treatment for other conditions	0.000	0.998	0.002
Z99.1 Dependence on respirator	0.002	0.998	0.000
K11.5 Sialolithiasis	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
X23 Contact with hornets, wasps and bees	0.000	0.998	0.002
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
I95.9 Hypotension, unspecified	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.002	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.998	0.000
M25.82 Other specified joint disorders (Upper arm)	0.002	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.000	0.998	0.002
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
M25.83 Other specified joint disorders (Forearm)	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
X23.0 Home	0.000	0.998	0.002
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
Z83.7 Family history of diseases of the digestive system	0.000	0.998	0.002
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
X23.8 Other specified place	0.000	0.998	0.002
X23.7 Farm	0.000	0.998	0.002
X23.6 Industrial and construction area	0.000	0.998	0.002
X23.5 Trade and service area	0.000	0.998	0.002
X23.4 Street and highway	0.000	0.998	0.002
X23.3 Sports and athletics area	0.000	0.998	0.002
X23.2 School, other institution and public administrative area	0.000	0.998	0.002
X23.1 Residential institution	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.002	0.998	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
Z96.7 Presence of other bone and tendon implants	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.002	0.998	0.000
D07.5 Prostate	0.002	0.998	0.000
D12.0 Caecum	0.002	0.998	0.000
L03.0 Cellulitis of finger and toe	0.000	0.998	0.002
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
R85.5 Abnormal microbiological findings	0.002	0.998	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.998	0.002
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.001	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.001	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.998	0.002
E10.3 With ophthalmic complications	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.002	0.998	0.000
M31.9 Necrotising vasculopathy, unspecified	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.998	0.001
Y44.7 Plasma substitutes	0.000	0.998	0.001
Y44.6 Natural blood and blood products	0.000	0.998	0.001
Y44.5 Thrombolytic drugs	0.000	0.998	0.001
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.998	0.001
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.998	0.001
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.998	0.001
M88.9 Paget's disease of bone, unspecified	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.001	0.998	0.000
Q67.7 Pectus carinatum	0.001	0.998	0.000
Q67.6 Pectus excavatum	0.001	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.998	0.000
Q67.3 Plagiocephaly	0.001	0.998	0.000
Q67.2 Dolichocephaly	0.001	0.998	0.000
Q67.1 Compression facies	0.001	0.998	0.000
Q67.0 Facial asymmetry	0.001	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.001	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.001	0.998	0.000
Q79.4 Prune belly syndrome	0.001	0.998	0.000
Q79.3 Gastroschisis	0.001	0.998	0.000
Q79.2 Exomphalos	0.001	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.001	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.001	0.998	0.000
R25.2 Cramp and spasm	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.001	0.998	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.001	0.998	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.001	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.001	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M88.8 Paget's disease of other bones	0.001	0.998	0.000
Q44.7 Other congenital malformations of liver	0.001	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.001	0.998	0.000
Q44.4 Choledochal cyst	0.001	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.001	0.998	0.000
Q44.2 Atresia of bile ducts	0.001	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.001	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.001	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.001
M25.87 Other specified joint disorders (Ankle and foot)	0.001	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000
Q68.3 Congenital bowing of femur	0.001	0.998	0.000
Q68.2 Congenital deformity of knee	0.001	0.998	0.000
Q68.1 Congenital deformity of hand	0.001	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.998	0.000
Q69.9 Polydactyly, unspecified	0.001	0.998	0.000
Q69.2 Accessory toe(s)	0.001	0.998	0.000
Q69.1 Accessory thumb(s)	0.001	0.998	0.000
Q69.0 Accessory finger(s)	0.001	0.998	0.000
Q70.9 Syndactyly, unspecified	0.001	0.998	0.000
Q70.4 Polysyndactyly	0.001	0.998	0.000
Q70.3 Webbed toes	0.001	0.998	0.000
Q70.2 Fused toes	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations