TreeWAS – Variant ID: rs359965

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.994	0.006
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.993	0.007
Chapter IX Diseases of the circulatory system	0.993	0.007
I30-I52 Other forms of heart disease	0.991	0.009
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.988	0.012
T81 Complications of procedures, not elsewhere classified	0.953	0.047
I47 Paroxysmal tachycardia	0.951	0.049
Chapter XIV Diseases of the genitourinary system	0.949	0.051
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.948	0.052
I70-I79 Diseases of arteries, arterioles and capillaries	0.941	0.059
Chapter VII Diseases of the eye and adnexa	0.938	0.062
N80-N98 Noninflammatory disorders of female genital tract	0.931	0.069
N84 Polyp of female genital tract	0.922	0.078
N84.0 Polyp of corpus uteri	0.915	0.085
I47.1 Supraventricular tachycardia	0.915	0.085
M20-M25 Other joint disorders	0.912	0.088
T85 Complications of other internal prosthetic devices, implants and grafts	0.904	0.096
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.892	0.108
T81.8 Other complications of procedures, not elsewhere classified	0.887	0.113
I49 Other cardiac arrhythmias	0.882	0.118
I42 Cardiomyopathy	0.877	0.123
N85 Other noninflammatory disorders of uterus, except cervix	0.871	0.129
M20 Acquired deformities of fingers and toes	0.865	0.135
Chapter XX External causes of morbidity and mortality	0.865	0.135
S20-S29 Injuries to the thorax	0.865	0.135
I45 Other conduction disorders	0.862	0.138
I71 Aortic aneurysm and dissection	0.858	0.142
S80-S89 Injuries to the knee and lower leg	0.855	0.145
I50 Heart failure	0.851	0.149
N17-N19 Renal failure	0.838	0.162
Chapter I Certain infectious and parasitic diseases	0.834	0.166
M05-M14 Inflammatory polyarthropathies	0.832	0.168
I34 Nonrheumatic mitral valve disorders	0.830	0.170
M40-M43 Deforming dorsopathies	0.813	0.187
Chapter VI Diseases of the nervous system	0.813	0.187
S00-S09 Injuries to the head	0.811	0.189
N93 Other abnormal uterine and vaginal bleeding	0.809	0.191
Chapter XII Diseases of the skin and subcutaneous tissue	0.802	0.198
H53-H54 Visual disturbances and blindness	0.798	0.202
N10-N16 Renal tubulo-interstitial diseases	0.796	0.204
T80 Complications following infusion, transfusion and therapeutic injection	0.795	0.205
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.795	0.205
Chapter V Mental and behavioural disorders	0.790	0.210
N18 Chronic renal failure	0.784	0.216
T88 Other complications of surgical and medical care, not elsewhere classified	0.782	0.218
I73 Other peripheral vascular diseases	0.781	0.219
N85.8 Other specified noninflammatory disorders of uterus	0.780	0.220
H30-H36 Disorders of choroid and retina	0.775	0.225
I38 Endocarditis, valve unspecified	0.773	0.227
M20.5 Other deformities of toe(s) (acquired)	0.772	0.228
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.771	0.229
I45.1 Other and unspecified right bundle-branch block	0.769	0.231
T85.4 Mechanical complication of breast prosthesis and implant	0.766	0.234
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.764	0.236
T85.2 Mechanical complication of intraocular lens	0.763	0.237
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.763	0.237
Chapter XXII Codes for special purposes	0.760	0.240
I20-I25 Ischaemic heart diseases	0.759	0.241
Chapter IV Endocrine, nutritional and metabolic diseases	0.759	0.241
I74 Arterial embolism and thrombosis	0.758	0.242
I50.9 Heart failure, unspecified	0.758	0.242
T79-T79 Certain early complications of trauma	0.757	0.243
S90-S99 Injuries to the ankle and foot	0.757	0.243
I33 Acute and subacute endocarditis	0.751	0.249
M06 Other rheumatoid arthritis	0.749	0.251
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.749	0.251
S22 Fracture of rib(s), sternum and thoracic spine	0.747	0.252
N86 Erosion and ectropion of cervix uteri	0.746	0.254
M25 Other joint disorders, not elsewhere classified	0.746	0.254
I44 Atrioventricular and left bundle-branch block	0.746	0.254
Chapter VIII Diseases of the ear and mastoid process	0.745	0.255
I42.0 Dilated cardiomyopathy	0.745	0.255
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.743	0.257
M20.4 Other hammer toe(s) (acquired)	0.741	0.259
I20 Angina pectoris	0.739	0.261
I47.2 Ventricular tachycardia	0.739	0.261
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.738	0.262
I49.3 Ventricular premature depolarisation	0.738	0.262
M20.0 Deformity of finger(s)	0.737	0.262
I20.9 Angina pectoris, unspecified	0.735	0.265
T66-T78 Other and unspecified effects of external causes	0.734	0.266
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.734	0.266
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.733	0.267
I49.9 Cardiac arrhythmia, unspecified	0.732	0.268
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.730	0.270
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.726	0.273
N85.0 Endometrial glandular hyperplasia	0.726	0.274
N99-N99 Other disorders of the genitourinary system	0.725	0.275
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.723	0.277
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.723	0.277
I42.9 Cardiomyopathy, unspecified	0.722	0.278
M24 Other specific joint derangements	0.720	0.280
S82 Fracture of lower leg, including ankle	0.719	0.281
I34.0 Mitral (valve) insufficiency	0.718	0.282
I73.9 Peripheral vascular disease, unspecified	0.718	0.282
N00-N08 Glomerular diseases	0.717	0.283
H10-H13 Disorders of conjunctiva	0.716	0.284
N90 Other noninflammatory disorders of vulva and perineum	0.715	0.285
Chapter XVI Certain conditions originating in the perinatal period	0.713	0.287
M43 Other deforming dorsopathies	0.713	0.287
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.712	0.288
T33-T35 Frostbite	0.712	0.288
T26-T28 Burns and corrosions confined to eye and internal organs	0.712	0.288
T20-T25 Burns and corrosions of external body surface, specified by site	0.712	0.288
T15-T19 Effects of foreign body entering through natural orifice	0.712	0.288
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.712	0.288
T00-T07 Injuries involving multiple body regions	0.712	0.288
S10-S19 Injuries to the neck	0.712	0.288
I00-I02 Acute rheumatic fever	0.712	0.288
I52 Other heart disorders in diseases classified elsewhere	0.711	0.289
I48 Atrial fibrillation and flutter	0.711	0.289
I43 Cardiomyopathy in diseases classified elsewhere	0.711	0.289
I41 Myocarditis in diseases classified elsewhere	0.711	0.289
I40 Acute myocarditis	0.711	0.289
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.711	0.289
I37 Pulmonary valve disorders	0.711	0.289
I36 Nonrheumatic tricuspid valve disorders	0.711	0.289
I32 Pericarditis in diseases classified elsewhere	0.711	0.289
I30 Acute pericarditis	0.711	0.289
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.710	0.290
I71.3 Abdominal aortic aneurysm, ruptured	0.709	0.291
T87 Complications peculiar to reattachment and amputation	0.708	0.291
T86 Failure and rejection of transplanted organs and tissues	0.708	0.291
N13 Obstructive and reflux uropathy	0.708	0.292
M70-M79 Other soft tissue disorders	0.707	0.293
N85.2 Hypertrophy of uterus	0.702	0.298
N88 Other noninflammatory disorders of cervix uteri	0.701	0.299
M20.1 Hallux valgus (acquired)	0.695	0.305
N84.1 Polyp of cervix uteri	0.694	0.306
S40-S49 Injuries to the shoulder and upper arm	0.693	0.306
I31 Other diseases of pericardium	0.691	0.309
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.690	0.310
N18.3 Chronic kidney disease, stage 3	0.690	0.310
M06.9 Rheumatoid arthritis, unspecified	0.690	0.310
N60-N64 Disorders of breast	0.690	0.310
I95-I99 Other and unspecified disorders of the circulatory system	0.689	0.311
I50.0 Congestive heart failure	0.689	0.311
M23 Internal derangement of knee	0.686	0.314
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.686	0.314
H25-H28 Disorders of lens	0.684	0.316
S80 Superficial injury of lower leg	0.684	0.316
G40-G47 Episodic and paroxysmal disorders	0.683	0.316
T81.9 Unspecified complication of procedure	0.683	0.317
T81.7 Vascular complications following a procedure, not elsewhere classified	0.683	0.317
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.683	0.317
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.683	0.317
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.683	0.317
I47.9 Paroxysmal tachycardia, unspecified	0.682	0.318
I47.0 Reentry ventricular arrhythmia	0.682	0.318
M21 Other acquired deformities of limbs	0.681	0.319
I77 Other disorders of arteries and arterioles	0.680	0.320
M91-M94 Chondropathies	0.680	0.320
M86-M90 Other osteopathies	0.680	0.320
M60-M63 Disorders of muscles	0.680	0.320
M00-M03 Infectious arthropathies	0.680	0.320
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.678	0.322
A30-A49 Other bacterial diseases	0.676	0.324
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.675	0.325
I72 Other aneurysm	0.675	0.325
I70 Atherosclerosis	0.675	0.325
S27 Injury of other and unspecified intrathoracic organs	0.673	0.327
H55-H59 Other disorders of eye and adnexa	0.673	0.327
H46-H48 Disorders of optic nerve and visual pathways	0.673	0.327
H43-H45 Disorders of vitreous body and globe	0.671	0.329
S00 Superficial injury of head	0.669	0.330
I51 Complications and ill-defined descriptions of heart disease	0.669	0.331
H40-H42 Glaucoma	0.669	0.331
G35-G37 Demyelinating diseases of the central nervous system	0.669	0.331
B95-B98 Bacterial, viral and other infectious agents	0.668	0.332
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.668	0.332
W20-W49 Exposure to inanimate mechanical forces	0.667	0.332
N93.0 Postcoital and contact bleeding	0.667	0.333
N98 Complications associated with artificial fertilisation	0.667	0.333
N91 Absent, scanty and rare menstruation	0.667	0.333
N82 Fistulae involving female genital tract	0.667	0.333
N96 Habitual aborter	0.667	0.333
I49.8 Other specified cardiac arrhythmias	0.666	0.334
L40-L45 Papulosquamous disorders	0.664	0.336
E10-E14 Diabetes mellitus	0.663	0.337
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.663	0.337
B07 Viral warts	0.662	0.338
H53 Visual disturbances	0.662	0.338
N84.9 Polyp of female genital tract, unspecified	0.661	0.339
N84.8 Polyp of other parts of female genital tract	0.661	0.339
N84.3 Polyp of vulva	0.661	0.339
N84.2 Polyp of vagina	0.661	0.339
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.660	0.340
W00-W19 Falls	0.660	0.340
N89 Other noninflammatory disorders of vagina	0.659	0.341
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.657	0.343
L80-L99 Other disorders of the skin and subcutaneous tissue	0.656	0.344
I78 Diseases of capillaries	0.654	0.345
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.654	0.346
M34 Systemic sclerosis	0.654	0.346
M33 Dermatopolymyositis	0.654	0.346
M32 Systemic lupus erythematosus	0.654	0.346
M31 Other necrotising vasculopathies	0.654	0.346
M30 Polyarteritis nodosa and related conditions	0.654	0.346
M22 Disorders of patella	0.654	0.346
N93.8 Other specified abnormal uterine and vaginal bleeding	0.653	0.347
S70-S79 Injuries to the hip and thigh	0.651	0.349
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.650	0.350
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.650	0.350
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.648	0.352
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.648	0.352
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.648	0.352
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.648	0.352
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.648	0.352
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.648	0.352
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.648	0.352
N18.4 Chronic kidney disease, stage 4	0.647	0.353
F00-F09 Organic, including symptomatic, mental disorders	0.646	0.354
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.645	0.355
I46 Cardiac arrest	0.643	0.356
F40-F48 Neurotic, stress-related and somatoform disorders	0.642	0.358
N25-N29 Other disorders of kidney and ureter	0.641	0.359
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.641	0.359
M43.1 Spondylolisthesis	0.641	0.359
T81.4 Infection following a procedure, not elsewhere classified	0.637	0.363
I49.5 Sick sinus syndrome	0.636	0.364
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.636	0.364
H36 Retinal disorders in diseases classified elsewhere	0.636	0.364
I05-I09 Chronic rheumatic heart diseases	0.635	0.364
T88.4 Failed or difficult intubation	0.634	0.366
M65-M68 Disorders of synovium and tendon	0.634	0.366
I49.4 Other and unspecified premature depolarisation	0.633	0.367
I49.2 Junctional premature depolarisation	0.633	0.367
I49.1 Atrial premature depolarisation	0.633	0.367
H54 Blindness and low vision	0.632	0.367
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.629	0.371
N18.5 Chronic kidney disease, stage 5	0.629	0.371
I42.8 Other cardiomyopathies	0.628	0.371
I42.7 Cardiomyopathy due to drugs and other external agents	0.628	0.371
I42.6 Alcoholic cardiomyopathy	0.628	0.371
I42.5 Other restrictive cardiomyopathy	0.628	0.371
I42.4 Endocardial fibroelastosis	0.628	0.371
I42.3 Endomyocardial (eosinophilic) disease	0.628	0.371
I42.2 Other hypertrophic cardiomyopathy	0.628	0.371
I42.1 Obstructive hypertrophic cardiomyopathy	0.628	0.371
S01 Open wound of head	0.627	0.373
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.627	0.373
M80-M85 Disorders of bone density and structure	0.625	0.375
N85.9 Noninflammatory disorder of uterus, unspecified	0.625	0.375
N85.7 Haematometra	0.625	0.375
N85.6 Intra-uterine synechiae	0.625	0.375
N85.5 Inversion of uterus	0.625	0.375
N85.3 Subinvolution of uterus	0.625	0.375
N85.1 Endometrial adenomatous hyperplasia	0.625	0.375
G20-G26 Extrapyramidal and movement disorders	0.624	0.375
E20-E35 Disorders of other endocrine glands	0.625	0.375
Chapter XV Pregnancy, childbirth and the puerperium	0.623	0.377
M45-M49 Spondylopathies	0.623	0.377
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.621	0.379
M79 Other soft tissue disorders, not elsewhere classified	0.621	0.379
M20.3 Other deformity of hallux (acquired)	0.620	0.380
I49.0 Ventricular fibrillation and flutter	0.620	0.380
S22.4 Multiple fractures of ribs	0.620	0.380
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.620	0.380
Y35-Y36 Legal intervention and operations of war	0.620	0.380
Y10-Y34 Event of undetermined intent	0.620	0.380
Y00-Y09 Assault	0.620	0.380
X85-X99 Assault	0.620	0.380
X60-X84 Intentional self-harm	0.620	0.380
X58-X59 Accidental exposure to other and unspecified factors	0.620	0.380
X50-X57 Overexertion, travel and privation	0.620	0.380
X40-X49 Accidental poisoning by and exposure to noxious substances	0.620	0.380
X30-X39 Exposure to forces of nature	0.620	0.380
X20-X29 Contact with venomous animals and plants	0.620	0.380
X10-X19 Contact with heat and hot substances	0.620	0.380
X00-X09 Exposure to smoke, fire and flames	0.620	0.380
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.620	0.380
W75-W84 Other accidental threats to breathing	0.620	0.380
W65-W74 Accidental drowning and submersion	0.620	0.380
W50-W64 Exposure to animate mechanical forces	0.620	0.380
V98-V99 Other and unspecified transport accidents	0.620	0.380
V95-V97 Air and space transport accidents	0.620	0.380
V90-V94 Water transport accidents	0.620	0.380
V80-V89 Other land transport accidents	0.620	0.380
V70-V79 Bus occupant injured in transport accident	0.620	0.380
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.620	0.380
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.620	0.380
V40-V49 Car occupant injured in transport accident	0.620	0.380
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.620	0.380
V20-V29 Motorcycle rider injured in transport accident	0.620	0.380
V01-V09 Pedestrian injured in transport accident	0.620	0.380
S29 Other and unspecified injuries of thorax	0.620	0.380
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.620	0.380
S26 Injury of heart	0.620	0.380
S25 Injury of blood vessels of thorax	0.620	0.380
S24 Injury of nerves and spinal cord at thorax level	0.620	0.380
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.620	0.380
S21 Open wound of thorax	0.620	0.380
S20 Superficial injury of thorax	0.620	0.380
B15-B19 Viral hepatitis	0.620	0.380
N19 Unspecified renal failure	0.620	0.380
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.619	0.381
M25.7 Osteophyte	0.618	0.382
I45.9 Conduction disorder, unspecified	0.618	0.382
I45.8 Other specified conduction disorders	0.618	0.382
I45.6 Preexcitation syndrome	0.618	0.382
I45.5 Other specified heart block	0.618	0.382
I45.4 Nonspecific intraventricular block	0.618	0.382
I45.3 Trifascicular block	0.618	0.382
I45.2 Bifascicular block	0.618	0.382
I45.0 Right fascicular block	0.618	0.382
L50-L54 Urticaria and erythema	0.617	0.383
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.617	0.383
S60-S69 Injuries to the wrist and hand	0.615	0.385
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.615	0.385
I71.8 Aortic aneurysm of unspecified site, ruptured	0.615	0.385
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.615	0.385
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.615	0.385
I71.1 Thoracic aortic aneurysm, ruptured	0.615	0.385
I71.0 Dissection of aorta [any part]	0.615	0.385
S82.8 Fractures of other parts of lower leg	0.615	0.385
N97 Female infertility	0.614	0.386
S89 Other and unspecified injuries of lower leg	0.613	0.387
S88 Traumatic amputation of lower leg	0.613	0.387
S87 Crushing injury of lower leg	0.613	0.387
S86 Injury of muscle and tendon at lower leg level	0.613	0.387
S85 Injury of blood vessels at lower leg level	0.613	0.387
S84 Injury of nerves at lower leg level	0.613	0.387
S81 Open wound of lower leg	0.613	0.387
G70-G73 Diseases of myoneural junction and muscle	0.613	0.387
N13.8 Other obstructive and reflux uropathy	0.612	0.388
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.611	0.389
M20.6 Acquired deformity of toe(s), unspecified	0.610	0.389
S22.0 Fracture of thoracic vertebra	0.608	0.392
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.608	0.392
B25-B34 Other viral diseases	0.608	0.392
M11 Other crystal arthropathies	0.607	0.393
M07 Psoriatic and enteropathic arthropathies	0.606	0.394
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.605	0.395
N88.8 Other specified noninflammatory disorders of cervix uteri	0.604	0.396
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.604	0.396
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.604	0.396
L20-L30 Dermatitis and eczema	0.604	0.396
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.603	0.396
S50-S59 Injuries to the elbow and forearm	0.602	0.397
N18.0 End-stage renal disease	0.601	0.399
N13.3 Other and unspecified hydronephrosis	0.600	0.400
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.599	0.400
V10-V19 Pedal cyclist injured in transport accident	0.599	0.401
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.598	0.402
B99-B99 Other infectious diseases	0.598	0.402
B90-B94 Sequelae of infectious and parasitic diseases	0.598	0.402
B85-B89 Pediculosis, acariasis and other infestations	0.598	0.402
B65-B83 Helminthiases	0.598	0.402
B50-B64 Protozoal diseases	0.598	0.402
B20-B24 Human immunodeficiency virus [HIV] disease	0.598	0.402
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.598	0.402
A80-A89 Viral infections of the central nervous system	0.598	0.402
A75-A79 Rickettsioses	0.598	0.402
A70-A74 Other diseases caused by chlamydiae	0.598	0.402
A65-A69 Other spirochaetal diseases	0.598	0.402
A50-A64 Infections with a predominantly sexual mode of transmission	0.598	0.402
A20-A28 Certain zoonotic bacterial diseases	0.598	0.402
A15-A19 Tuberculosis	0.598	0.402
M14 Arthropathies in other diseases classified elsewhere	0.596	0.404
M12 Other specific arthropathies	0.596	0.404
M09 Juvenile arthritis in diseases classified elsewhere	0.596	0.404
M08 Juvenile arthritis	0.596	0.404
M05 Seropositive rheumatoid arthritis	0.596	0.404
H52 Disorders of refraction and accommodation	0.595	0.405
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.595	0.405
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.595	0.405
I34.8 Other nonrheumatic mitral valve disorders	0.595	0.405
I34.2 Nonrheumatic mitral (valve) stenosis	0.595	0.405
G30-G32 Other degenerative diseases of the nervous system	0.593	0.407
N81 Female genital prolapse	0.593	0.407
M41 Scoliosis	0.592	0.408
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.592	0.408
Y60-Y69 Misadventures to patients during surgical and medical care	0.592	0.408
S30 Superficial injury of abdomen, lower back and pelvis	0.590	0.410
S06 Intracranial injury	0.590	0.410
E11 Non-insulin-dependent diabetes mellitus	0.590	0.410
M13 Other arthritis	0.589	0.411
M25.5 Pain in joint	0.589	0.411
T79 Certain early complications of trauma, not elsewhere classified	0.588	0.411
I44.0 Atrioventricular block, first degree	0.588	0.412
S92 Fracture of foot, except ankle	0.587	0.412
S00.8 Superficial injury of other parts of head	0.586	0.414
I35 Nonrheumatic aortic valve disorders	0.585	0.414
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.585	0.415
N85.4 Malposition of uterus	0.585	0.415
I34.1 Mitral (valve) prolapse	0.585	0.415
D70-D77 Other diseases of blood and blood-forming organs	0.585	0.415
N30-N39 Other diseases of urinary system	0.584	0.416
T81.3 Disruption of operation wound, not elsewhere classified	0.583	0.417
M42 Spinal osteochondrosis	0.583	0.417
M40 Kyphosis and lordosis	0.583	0.417
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.583	0.417
G00-G09 Inflammatory diseases of the central nervous system	0.583	0.417
M24.4 Recurrent dislocation and subluxation of joint	0.582	0.418
S08 Traumatic amputation of part of head	0.581	0.419
S07 Crushing injury of head	0.581	0.419
S05 Injury of eye and orbit	0.581	0.419
S04 Injury of cranial nerves	0.581	0.419
S03 Dislocation, sprain and strain of joints and ligaments of head	0.581	0.419
M10 Gout	0.580	0.420
N95 Menopausal and other perimenopausal disorders	0.580	0.420
T36-T50 Poisoning by drugs, medicaments and biological substances	0.579	0.421
H35 Other retinal disorders	0.579	0.421
I33.0 Acute and subacute infective endocarditis	0.579	0.421
L10-L14 Bullous disorders	0.575	0.425
H21 Other disorders of iris and ciliary body	0.575	0.425
S09 Other and unspecified injuries of head	0.573	0.426
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.573	0.427
H65-H75 Diseases of middle ear and mastoid	0.573	0.427
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.571	0.428
H80-H83 Diseases of inner ear	0.571	0.429
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.571	0.429
N15 Other renal tubulo-interstitial diseases	0.571	0.429
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.571	0.429
N11 Chronic tubulo-interstitial nephritis	0.571	0.429
N10 Acute tubulo-interstitial nephritis	0.571	0.429
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.570	0.430
T80.6 Other serum reactions	0.570	0.430
T80.5 Anaphylactic shock due to serum	0.570	0.430
T80.4 Rh incompatibility reaction	0.570	0.430
T80.3 ABO incompatibility reaction	0.570	0.430
T80.2 Infections following infusion, transfusion and therapeutic injection	0.570	0.430
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.570	0.430
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.570	0.430
H33 Retinal detachments and breaks	0.570	0.430
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.570	0.430
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.570	0.430
T84.3 Mechanical complication of other bone devices, implants and grafts	0.570	0.430
T84.2 Mechanical complication of internal fixation device of other bones	0.570	0.430
H25 Senile cataract	0.570	0.430
N70-N77 Inflammatory diseases of female pelvic organs	0.569	0.431
E00-E07 Disorders of thyroid gland	0.569	0.431
G47 Sleep disorders	0.569	0.431
Y88 Sequelae of surgical and medical care as external cause	0.567	0.433
N08 Glomerular disorders in diseases classified elsewhere	0.567	0.433
F99-F99 Unspecified mental disorder	0.567	0.433
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.567	0.433
F80-F89 Disorders of psychological development	0.567	0.433
F70-F79 Mental retardation	0.567	0.433
F60-F69 Disorders of adult personality and behaviour	0.567	0.433
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.567	0.433
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.566	0.434
D80-D89 Certain disorders involving the immune mechanism	0.566	0.434
G35 Multiple sclerosis	0.565	0.435
M43.17 Spondylolisthesis (Lumbosacral region)	0.565	0.435
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.564	0.436
Q20-Q28 Congenital malformations of the circulatory system	0.563	0.437
F05 Delirium, not induced by alcohol and other psychoactive substances	0.563	0.437
S82.4 Fracture of fibula alone	0.562	0.437
N18.8 Other chronic renal failure	0.562	0.438
N18.2 Chronic kidney disease, stage 2	0.562	0.438
N18.1 Chronic kidney disease, stage 1	0.562	0.438
S80.0 Contusion of knee	0.562	0.438
I27 Other pulmonary heart diseases	0.561	0.439
T88.9 Complication of surgical and medical care, unspecified	0.561	0.439
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.561	0.439
T88.7 Unspecified adverse effect of drug or medicament	0.561	0.439
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.561	0.439
T88.5 Other complications of anaesthesia	0.561	0.439
T88.3 Malignant hyperthermia due to anaesthesis	0.561	0.439
T88.2 Shock due to anaesthesia	0.561	0.439
T88.1 Other complications following immunisation, not elsewhere classified	0.561	0.439
T88.0 Infection following immunisation	0.561	0.439
N81.2 Incomplete uterovaginal prolapse	0.560	0.440
I73.8 Other specified peripheral vascular diseases	0.560	0.440
I73.1 Thromboangiitis obliterans [Buerger]	0.560	0.440
L43 Lichen planus	0.560	0.440
H60-H62 Diseases of external ear	0.558	0.441
G25 Other extrapyramidal and movement disorders	0.558	0.441
H10 Conjunctivitis	0.557	0.443
H34 Retinal vascular occlusions	0.556	0.444
H32 Chorioretinal disorders in diseases classified elsewhere	0.556	0.444
H31 Other disorders of choroid	0.556	0.444
H30 Chorioretinal inflammation	0.556	0.444
I51.7 Cardiomegaly	0.555	0.444
Y86 Sequelae of other accidents	0.555	0.445
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.553	0.447
S37 Injury of urinary and pelvic organs	0.553	0.447
S36 Injury of intra-abdominal organs	0.553	0.447
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.553	0.447
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.553	0.447
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.553	0.447
S31 Open wound of abdomen, lower back and pelvis	0.553	0.447
N60 Benign mammary dysplasia	0.552	0.448
A49 Bacterial infection of unspecified site	0.551	0.449
T78 Adverse effects, not elsewhere classified	0.548	0.452
D55-D59 Haemolytic anaemias	0.548	0.452
N90.5 Atrophy of vulva	0.547	0.453
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.547	0.453
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.547	0.453
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.547	0.453
T82.4 Mechanical complication of vascular dialysis catheter	0.547	0.453
T82.3 Mechanical complication of other vascular grafts	0.547	0.453
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.547	0.453
T82.1 Mechanical complication of cardiac electronic device	0.547	0.453
T82.0 Mechanical complication of heart valve prosthesis	0.547	0.453
S32 Fracture of lumbar spine and pelvis	0.546	0.454
S02 Fracture of skull and facial bones	0.545	0.454
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.545	0.455
I23 Certain current complications following acute myocardial infarction	0.544	0.455

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations