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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs36071623
log Bayes Factor = 9.38139
Chromosome 13   position 88,970,555  (GRCh37) Explore rs36071623 on Ensembl!
Variant rs36071623 is part of Cluster X0332

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.998 0.002 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
Chapter II Neoplasms
0.995 0.005 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.995 0.005 0.000
M65-M68 Disorders of synovium and tendon
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.993 0.007 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.992 0.008 0.000
M65 Synovitis and tenosynovitis
0.991 0.009 0.000
R20 Disturbances of skin sensation
0.990 0.010 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.988 0.012 0.000
M06 Other rheumatoid arthritis
0.988 0.012 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.987 0.013 0.000
M06.9 Rheumatoid arthritis, unspecified
0.984 0.016 0.000
L90 Atrophic disorders of skin
0.978 0.022 0.000
M65.3 Trigger finger
0.969 0.031 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.968 0.032 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.965 0.035 0.000
M80-M85 Disorders of bone density and structure
0.962 0.038 0.000
L90.5 Scar conditions and fibrosis of skin
0.961 0.039 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.954 0.046 0.000
M65.34 Trigger finger-Hand
0.953 0.047 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.950 0.050 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.943 0.057 0.000
D00-D09 In situ neoplasms
0.938 0.062 0.000
M86-M90 Other osteopathies
0.934 0.066 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.931 0.069 0.000
L81 Other disorders of pigmentation
0.928 0.072 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.926 0.074 0.000
M81 Osteoporosis without pathological fracture
0.923 0.077 0.000
M60-M63 Disorders of muscles
0.922 0.078 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.921 0.079 0.000
E70-E90 Metabolic disorders
0.917 0.083 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.916 0.084 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.915 0.085 0.000
D80-D89 Certain disorders involving the immune mechanism
0.914 0.086 0.000
D75 Other diseases of blood and blood-forming organs
0.913 0.087 0.000
M81.9 Osteoporosis, unspecified
0.892 0.108 0.000
Chapter I Certain infectious and parasitic diseases
0.885 0.115 0.000
C64-C68 Malignant neoplasms of urinary tract
0.885 0.115 0.000
L60-L75 Disorders of skin appendages
0.884 0.116 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.884 0.116 0.000
Chapter VII Diseases of the eye and adnexa
0.880 0.120 0.000
D55-D59 Haemolytic anaemias
0.876 0.124 0.000
R42 Dizziness and giddiness
0.872 0.128 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.870 0.130 0.000
D86 Sarcoidosis
0.870 0.130 0.000
M62 Other disorders of muscle
0.867 0.133 0.000
E50-E64 Other nutritional deficiencies
0.864 0.136 0.000
D45 Polycythaemia vera
0.862 0.138 0.000
R40 Somnolence, stupor and coma
0.861 0.139 0.000
E83 Disorders of mineral metabolism
0.858 0.142 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.858 0.142 0.000
R27 Other lack of coordination
0.858 0.142 0.000
D75.1 Secondary polycythaemia
0.855 0.145 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.855 0.145 0.000
L90.0 Lichen sclerosus et atrophicus
0.854 0.146 0.000
L89 Decubitus ulcer
0.852 0.148 0.000
E86 Volume depletion
0.850 0.150 0.000
E40-E46 Malnutrition
0.849 0.151 0.000
M05 Seropositive rheumatoid arthritis
0.848 0.152 0.000
M89 Other disorders of bone
0.842 0.158 0.000
C15-C26 Malignant neoplasms of digestive organs
0.840 0.160 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.832 0.168 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.831 0.169 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.829 0.170 0.000
R20.2 Paraesthesia of skin
0.829 0.171 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.828 0.172 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.827 0.173 0.000
M62.8 Other specified disorders of muscle
0.827 0.173 0.000
L60 Nail disorders
0.826 0.174 0.000
D07.5 Prostate
0.825 0.175 0.000
D03 Melanoma in situ
0.825 0.175 0.000
L20-L30 Dermatitis and eczema
0.824 0.176 0.000
H53-H54 Visual disturbances and blindness
0.824 0.176 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.824 0.176 0.000
E20-E35 Disorders of other endocrine glands
0.823 0.177 0.000
D69 Purpura and other haemorrhagic conditions
0.822 0.178 0.000
M20-M25 Other joint disorders
0.815 0.185 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.811 0.189 0.000
C51-C58 Malignant neoplasms of female genital organs
0.810 0.190 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.809 0.191 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.807 0.193 0.000
L81.9 Disorder of pigmentation, unspecified
0.804 0.196 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.803 0.197 0.000
A30-A49 Other bacterial diseases
0.800 0.200 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.798 0.202 0.000
E83.5 Disorders of calcium metabolism
0.798 0.202 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.797 0.203 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.795 0.205 0.000
R25 Abnormal involuntary movements
0.795 0.205 0.000
M70-M79 Other soft tissue disorders
0.794 0.206 0.000
C91 Lymphoid leukaemia
0.792 0.208 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.792 0.208 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.792 0.208 0.000
R27.0 Ataxia, unspecified
0.791 0.209 0.000
L81.4 Other melanin hyperpigmentation
0.790 0.210 0.000
M65.8 Other synovitis and tenosynovitis
0.790 0.210 0.000
R40.2 Coma, unspecified
0.789 0.211 0.000
L89.1 Stage II decubitus ulcer
0.788 0.212 0.000
M50-M54 Other dorsopathies
0.788 0.212 0.000
D72 Other disorders of white blood cells
0.787 0.213 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.787 0.213 0.000
C15 Malignant neoplasm of oesophagus
0.785 0.215 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.785 0.215 0.000
Chapter XIV Diseases of the genitourinary system
0.785 0.215 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.784 0.216 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.784 0.216 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.783 0.217 0.000
N13 Obstructive and reflux uropathy
0.783 0.217 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.782 0.218 0.000
N10-N16 Renal tubulo-interstitial diseases
0.780 0.220 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.780 0.220 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.780 0.220 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.778 0.222 0.000
E46 Unspecified protein-energy malnutrition
0.773 0.227 0.000
H25-H28 Disorders of lens
0.771 0.229 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.767 0.233 0.000
M90 Osteopathies in diseases classified elsewhere
0.767 0.233 0.000
R43 Disturbances of smell and taste
0.765 0.235 0.000
H53 Visual disturbances
0.761 0.239 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.761 0.239 0.000
M35 Other systemic involvement of connective tissue
0.760 0.240 0.000
C20 Malignant neoplasm of rectum
0.760 0.240 0.000
E53 Deficiency of other B group vitamins
0.759 0.241 0.000
A00-A09 Intestinal infectious diseases
0.759 0.241 0.000
M80 Osteoporosis with pathological fracture
0.758 0.242 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.758 0.242 0.000
L81.8 Other specified disorders of pigmentation
0.758 0.242 0.000
L85 Other epidermal thickening
0.757 0.243 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.757 0.243 0.000
D86.9 Sarcoidosis, unspecified
0.756 0.244 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.755 0.245 0.000
H30-H36 Disorders of choroid and retina
0.754 0.246 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.754 0.246 0.000
Chapter IX Diseases of the circulatory system
0.754 0.246 0.000
D59 Acquired haemolytic anaemia
0.753 0.247 0.000
L70 Acne
0.753 0.247 0.000
L60.8 Other nail disorders
0.750 0.250 0.000
M67 Other disorders of synovium and tendon
0.749 0.251 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.748 0.252 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.748 0.252 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.747 0.253 0.000
D86.0 Sarcoidosis of lung
0.747 0.253 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.746 0.254 0.000
D68 Other coagulation defects
0.745 0.255 0.000
D47.1 Chronic myeloproliferative disease
0.745 0.255 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.745 0.255 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.744 0.256 0.000
C48.2 Peritoneum, unspecified
0.743 0.257 0.000
D50-D53 Nutritional anaemias
0.741 0.259 0.000
D04 Carcinoma in situ of skin
0.740 0.260 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.740 0.260 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.740 0.260 0.000
C66 Malignant neoplasm of ureter
0.739 0.261 0.000
Q60-Q64 Congenital malformations of the urinary system
0.736 0.264 0.000
R26 Abnormalities of gait and mobility
0.735 0.264 0.000
N17-N19 Renal failure
0.734 0.266 0.000
I73 Other peripheral vascular diseases
0.733 0.267 0.000
D73 Diseases of spleen
0.731 0.269 0.000
M40-M43 Deforming dorsopathies
0.730 0.270 0.000
N13.3 Other and unspecified hydronephrosis
0.730 0.270 0.000
M35.3 Polymyalgia rheumatica
0.729 0.271 0.000
M91-M94 Chondropathies
0.729 0.271 0.000
M86 Osteomyelitis
0.729 0.271 0.000
R21 Rash and other nonspecific skin eruption
0.728 0.272 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.728 0.272 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.727 0.273 0.000
I73.9 Peripheral vascular disease, unspecified
0.725 0.275 0.000
C15.9 Oesophagus, unspecified
0.724 0.276 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.723 0.277 0.000
C88 Malignant immunoproliferative diseases
0.721 0.278 0.000
M54 Dorsalgia
0.722 0.278 0.000
M84 Disorders of continuity of bone
0.721 0.279 0.000
E83.3 Disorders of phosphorus metabolism
0.720 0.280 0.000
M06.0 Seronegative rheumatoid arthritis
0.720 0.280 0.000
M11 Other crystal arthropathies
0.719 0.281 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.718 0.282 0.000
M89.9 Disorder of bone, unspecified
0.717 0.283 0.000
M10 Gout
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.716 0.284 0.000
H33 Retinal detachments and breaks
0.716 0.284 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.715 0.284 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.714 0.285 0.000
M89.8 Other specified disorders of bone
0.714 0.286 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.714 0.286 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
L10-L14 Bullous disorders
0.713 0.286 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.713 0.287 0.000
C53 Malignant neoplasm of cervix uteri
0.713 0.287 0.000
Chapter XX External causes of morbidity and mortality
0.712 0.288 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.712 0.288 0.000
M14 Arthropathies in other diseases classified elsewhere
0.712 0.288 0.000
M12 Other specific arthropathies
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.712 0.288 0.000
M08 Juvenile arthritis
0.712 0.288 0.000
M65.2 Calcific tendinitis
0.711 0.289 0.000
M65.1 Other infective (teno)synovitis
0.711 0.289 0.000
M65.0 Abscess of tendon sheath
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
D86.8 Sarcoidosis of other and combined sites
0.710 0.290 0.000
R20.3 Hyperaesthesia
0.710 0.290 0.000
R20.1 Hypoaesthesia of skin
0.710 0.290 0.000
R20.0 Anaesthesia of skin
0.710 0.290 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.708 0.292 0.000
L94 Other localised connective tissue disorders
0.708 0.292 0.000
L87 Transepidermal elimination disorders
0.708 0.292 0.000
L88 Pyoderma gangrenosum
0.708 0.292 0.000
L86 Keratoderma in diseases classified elsewhere
0.708 0.292 0.000
L80 Vitiligo
0.708 0.292 0.000
M06.8 Other specified rheumatoid arthritis
0.708 0.292 0.000
M06.4 Inflammatory polyarthropathy
0.708 0.292 0.000
M06.3 Rheumatoid nodule
0.708 0.292 0.000
M06.2 Rheumatoid bursitis
0.708 0.292 0.000
M06.1 Adult-onset Still's disease
0.708 0.292 0.000
E73 Lactose intolerance
0.708 0.292 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.706 0.294 0.000
H33.2 Serous retinal detachment
0.706 0.294 0.000
E27 Other disorders of adrenal gland
0.706 0.294 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.706 0.294 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.706 0.294 0.000
M66 Spontaneous rupture of synovium and tendon
0.705 0.295 0.000
L50-L54 Urticaria and erythema
0.704 0.295 0.000
D58 Other hereditary haemolytic anaemias
0.703 0.297 0.000
D06 Carcinoma in situ of cervix uteri
0.703 0.297 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.702 0.298 0.000
L90.9 Atrophic disorder of skin, unspecified
0.701 0.299 0.000
L90.8 Other atrophic disorders of skin
0.701 0.299 0.000
L90.6 Striae atrophicae
0.701 0.299 0.000
L90.4 Acrodermatitis chronica atrophicans
0.701 0.299 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.701 0.299 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.701 0.299 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.701 0.299 0.000
M07 Psoriatic and enteropathic arthropathies
0.701 0.299 0.000
H25 Senile cataract
0.701 0.299 0.000
M87 Osteonecrosis
0.699 0.301 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.699 0.301 0.000
R23 Other skin changes
0.698 0.302 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.696 0.304 0.000
H25.0 Senile incipient cataract
0.696 0.304 0.000
N60-N64 Disorders of breast
0.695 0.305 0.000
M65.39 Trigger finger-Site unspec
0.695 0.305 0.000
M65.38 Trigger finger-Other
0.695 0.305 0.000
M65.37 Trigger finger-Ankle/foot
0.695 0.305 0.000
M65.36 Trigger finger-Lower leg
0.695 0.305 0.000
M65.35 Trigger finger-Pelvic/thigh
0.695 0.305 0.000
M65.33 Trigger finger-Forearm
0.695 0.305 0.000
M65.32 Trigger finger-Upper arm
0.695 0.305 0.000
M65.31 Trigger finger-Shldr region
0.695 0.305 0.000
M65.30 Trigger finger-Mult sites
0.695 0.305 0.000
M24 Other specific joint derangements
0.694 0.306 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.694 0.306 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.694 0.306 0.000
M77 Other enthesopathies
0.693 0.307 0.000
D41.4 Bladder
0.693 0.307 0.000
R46 Symptoms and signs involving appearance and behaviour
0.692 0.308 0.000
M22 Disorders of patella
0.691 0.309 0.000
M81.4 Drug-induced osteoporosis
0.691 0.309 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.690 0.310 0.000
M83 Adult osteomalacia
0.689 0.310 0.000
M82 Osteoporosis in diseases classified elsewhere
0.689 0.310 0.000
H53.1 Subjective visual disturbances
0.689 0.311 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.687 0.313 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.687 0.313 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.686 0.314 0.000
C17 Malignant neoplasm of small intestine
0.685 0.315 0.000
C81 Hodgkin's disease
0.685 0.315 0.000
E53.8 Deficiency of other specified B group vitamins
0.684 0.316 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.682 0.318 0.000
C91.0 Acute lymphoblastic leukaemia
0.681 0.319 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.681 0.319 0.000
E83.4 Disorders of magnesium metabolism
0.679 0.321 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.678 0.322 0.000
A48 Other bacterial diseases, not elsewhere classified
0.677 0.323 0.000
H54 Blindness and low vision
0.677 0.323 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.676 0.323 0.000
D74 Methaemoglobinaemia
0.676 0.323 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.676 0.323 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.676 0.323 0.000
I71 Aortic aneurysm and dissection
0.676 0.324 0.000
R25.2 Cramp and spasm
0.676 0.324 0.000
E55 Vitamin D deficiency
0.674 0.325 0.000
R73 Elevated blood glucose level
0.674 0.326 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.673 0.327 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.673 0.327 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.673 0.327 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.673 0.327 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.673 0.327 0.000
R45 Symptoms and signs involving emotional state
0.671 0.329 0.000
M85 Other disorders of bone density and structure
0.670 0.329 0.000
I74 Arterial embolism and thrombosis
0.670 0.330 0.000
L21 Seborrhoeic dermatitis
0.670 0.330 0.000
E61 Deficiency of other nutrient elements
0.669 0.331 0.000
N60 Benign mammary dysplasia
0.669 0.331 0.000
D66 Hereditary factor VIII deficiency
0.668 0.332 0.000
C65 Malignant neoplasm of renal pelvis
0.667 0.332 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.666 0.333 0.000
L81.7 Pigmented purpuric dermatosis
0.666 0.334 0.000
L81.6 Other disorders of diminished melanin formation
0.666 0.334 0.000
L81.5 Leukoderma, not elsewhere classified
0.666 0.334 0.000
L81.3 Cafe au lait spots
0.666 0.334 0.000
L81.2 Freckles
0.666 0.334 0.000
L81.1 Chloasma
0.666 0.334 0.000
L81.0 Postinflammatory hyperpigmentation
0.666 0.334 0.000
R71 Abnormality of red blood cells
0.666 0.334 0.000
M34 Systemic sclerosis
0.666 0.334 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.665 0.334 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.664 0.336 0.000
C95 Leukaemia of unspecified cell type
0.664 0.336 0.000
C94 Other leukaemias of specified cell type
0.664 0.336 0.000
C93 Monocytic leukaemia
0.664 0.336 0.000
C86 Other specified types of T/NK-cell lymphoma
0.664 0.336 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.664 0.336 0.000
A41 Other septicaemia
0.663 0.337 0.000
H27 Other disorders of lens
0.663 0.337 0.000
E88 Other metabolic disorders
0.663 0.337 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.662 0.337 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.662 0.338 0.000
C23 Malignant neoplasm of gallbladder
0.662 0.338 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.662 0.338 0.000
D72.8 Other specified disorders of white blood cells
0.662 0.338 0.000
M81.8 Other osteoporosis
0.662 0.338 0.000
M81.6 Localised osteoporosis [Lequesne]
0.662 0.338 0.000
M81.5 Idiopathic osteoporosis
0.662 0.338 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.662 0.338 0.000
M81.2 Osteoporosis of disuse
0.662 0.338 0.000
M81.1 Postoophorectomy osteoporosis
0.662 0.338 0.000
M81.0 Postmenopausal osteoporosis
0.662 0.338 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.661 0.339 0.000
M61 Calcification and ossification of muscle
0.661 0.339 0.000
M60 Myositis
0.661 0.339 0.000
C48.1 Specified parts of peritoneum
0.661 0.339 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.660 0.340 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.660 0.340 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.660 0.340 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.660 0.340 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.660 0.340 0.000
H10-H13 Disorders of conjunctiva
0.660 0.340 0.000
M81.98 Osteoporosis, unspecified (Other)
0.659 0.341 0.000
L93 Lupus erythematosus
0.659 0.341 0.000
L70.0 Acne vulgaris
0.659 0.341 0.000
L60.9 Nail disorder, unspecified
0.658 0.342 0.000
D44.4 Craniopharyngeal duct
0.658 0.342 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.657 0.342 0.000
E85 Amyloidosis
0.657 0.342 0.000
E84 Cystic fibrosis
0.657 0.342 0.000
E79 Disorders of purine and pyrimidine metabolism
0.657 0.342 0.000
E77 Disorders of glycoprotein metabolism
0.657 0.342 0.000
E76 Disorders of glycosaminoglycan metabolism
0.657 0.342 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.657 0.342 0.000
E74 Other disorders of carbohydrate metabolism
0.657 0.342 0.000
E72 Other disorders of amino-acid metabolism
0.657 0.342 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.657 0.342 0.000
E70 Disorders of aromatic amino-acid metabolism
0.657 0.342 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.657 0.342 0.000
D86.1 Sarcoidosis of lymph nodes
0.657 0.343 0.000
M75 Shoulder lesions
0.657 0.343 0.000
Q61 Cystic kidney disease
0.657 0.343 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.657 0.343 0.000
C46 Kaposi's sarcoma
0.657 0.343 0.000
D67 Hereditary factor IX deficiency
0.656 0.344 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.656 0.344 0.000
D84 Other immunodeficiencies
0.655 0.345 0.000
D83 Common variable immunodeficiency
0.655 0.345 0.000
D82 Immunodeficiency associated with other major defects
0.655 0.345 0.000
D81 Combined immunodeficiencies
0.655 0.345 0.000
D80 Immunodeficiency with predominantly antibody defects
0.655 0.345 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.655 0.345 0.000
A49 Bacterial infection of unspecified site
0.655 0.345 0.000
D75.2 Essential thrombocytosis
0.654 0.345 0.000
D75.0 Familial erythrocytosis
0.654 0.345 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.654 0.346 0.000
C45 Mesothelioma
0.653 0.347 0.000
D51 Vitamin B12 deficiency anaemia
0.652 0.348 0.000
M62.88 Other specified disorders of muscle (Other)
0.652 0.348 0.000
B15-B19 Viral hepatitis
0.652 0.348 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.651 0.349 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.649 0.351 0.000
L20 Atopic dermatitis
0.649 0.351 0.000
R41.3 Other amnesia
0.649 0.351 0.000
D69.5 Secondary thrombocytopenia
0.648 0.352 0.000
B99-B99 Other infectious diseases
0.647 0.353 0.000
M90.7 Fracture of bone in neoplastic disease
0.647 0.353 0.000
N18 Chronic renal failure
0.646 0.354 0.000
M54.9 Dorsalgia, unspecified
0.646 0.354 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.646 0.354 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.645 0.354 0.000
R50-R69 General symptoms and signs
0.645 0.355 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.644 0.356 0.000
N99-N99 Other disorders of the genitourinary system
0.644 0.356 0.000
C53.9 Cervix uteri, unspecified
0.643 0.357 0.000
C15.5 Lower third of oesophagus
0.643 0.357 0.000
L65 Other nonscarring hair loss
0.642 0.357 0.000
N17 Acute renal failure
0.642 0.358 0.000
B35-B49 Mycoses
0.640 0.360 0.000
L73 Other follicular disorders
0.640 0.360 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.640 0.360 0.000
E28 Ovarian dysfunction
0.640 0.360 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.640 0.360 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.640 0.360 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.640 0.360 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.640 0.360 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.640 0.360 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.640 0.360 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.640 0.360 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.640 0.360 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.639 0.361 0.000
D68.9 Coagulation defect, unspecified
0.639 0.361 0.000
C21 Malignant neoplasm of anus and anal canal
0.637 0.362 0.000
B00 Herpesviral [herpes simplex] infections
0.636 0.364 0.000
E87.7 Fluid overload
0.636 0.364 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.635 0.365 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.635 0.365 0.000
B50-B64 Protozoal diseases
0.635 0.365 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.635 0.365 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.635 0.365 0.000
A75-A79 Rickettsioses
0.635 0.365 0.000
A70-A74 Other diseases caused by chlamydiae
0.635 0.365 0.000
A65-A69 Other spirochaetal diseases
0.635 0.365 0.000
A20-A28 Certain zoonotic bacterial diseases
0.635 0.365 0.000
A15-A19 Tuberculosis
0.635 0.365 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.634 0.366 0.000
L75 Apocrine sweat disorders
0.634 0.366 0.000
L74 Eccrine sweat disorders
0.634 0.366 0.000
L68 Hypertrichosis
0.634 0.366 0.000
L67 Hair colour and hair shaft abnormalities
0.634 0.366 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.634 0.366 0.000
L64 Androgenic alopecia
0.634 0.366 0.000
L63 Alopecia areata
0.634 0.366 0.000
L62 Nail disorders in diseases classified elsewhere
0.634 0.366 0.000
C83.3 Large cell (diffuse)
0.633 0.367 0.000
Q00-Q07 Congenital malformations of the nervous system
0.633 0.367 0.000
B01 Varicella [chickenpox]
0.632 0.368 0.000
Chapter XXII Codes for special purposes
0.632 0.368 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.632 0.368 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.629 0.371 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.628 0.372 0.000
D57 Sickle-cell disorders
0.628 0.372 0.000
D56 Thalassaemia
0.628 0.372 0.000
D55 Anaemia due to enzyme disorders
0.628 0.372 0.000
M88 Paget's disease of bone [osteitis deformans]
0.628 0.372 0.000
B65-B83 Helminthiases
0.627 0.373 0.000
E87.5 Hyperkalaemia
0.627 0.373 0.000
E26 Hyperaldosteronism
0.627 0.373 0.000
D59.1 Other autoimmune haemolytic anaemias
0.627 0.373 0.000
M31 Other necrotising vasculopathies
0.626 0.374 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.626 0.374 0.000
L60.2 Onychogryphosis
0.626 0.374 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.624 0.375 0.000
D07.6 Other and unspecified male genital organs
0.624 0.376 0.000
D07.4 Penis
0.624 0.376 0.000
D07.3 Other and unspecified female genital organs
0.624 0.376 0.000
D07.2 Vagina
0.624 0.376 0.000
D07.0 Endometrium
0.624 0.376 0.000
D86.3 Sarcoidosis of skin
0.624 0.376 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.624 0.376 0.000
L60.0 Ingrowing nail
0.624 0.376 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.624 0.376 0.000
R77 Other abnormalities of plasma proteins
0.623 0.377 0.000
C34 Malignant neoplasm of bronchus and lung
0.623 0.377 0.000
R73.9 Hyperglycaemia, unspecified
0.623 0.377 0.000
R43.0 Anosmia
0.622 0.378 0.000
M62.9 Disorder of muscle, unspecified
0.622 0.378 0.000
M62.6 Muscle strain
0.622 0.378 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.622 0.378 0.000
M62.4 Contracture of muscle
0.622 0.378 0.000
M62.3 Immobility syndrome (paraplegic)
0.622 0.378 0.000
M62.2 Ischaemic infarction of muscle
0.622 0.378 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.622 0.378 0.000
M62.0 Diastasis of muscle
0.622 0.378 0.000
M75.1 Rotator cuff syndrome
0.620 0.380 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.619 0.380 0.000
E63 Other nutritional deficiencies
0.619 0.380 0.000
E56 Other vitamin deficiencies
0.619 0.380 0.000
E51 Thiamine deficiency
0.619 0.380 0.000
E50 Vitamin A deficiency
0.619 0.380 0.000
E60 Dietary zinc deficiency
0.619 0.380 0.000
E59 Dietary selenium deficiency
0.619 0.380 0.000
E58 Dietary calcium deficiency
0.619 0.380 0.000
E54 Ascorbic acid deficiency
0.619 0.380 0.000
E52 Niacin deficiency [pellagra]
0.619 0.380 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.619 0.381 0.000
L83 Acanthosis nigricans
0.619 0.381 0.000
I77 Other disorders of arteries and arterioles
0.618 0.381 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.618 0.382 0.000
R40.1 Stupor
0.617 0.382 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.617 0.383 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.617 0.383 0.000
R27.8 Other and unspecified lack of coordination
0.616 0.384 0.000
D46 Myelodysplastic syndromes
0.616 0.384 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.616 0.384 0.000
R55 Syncope and collapse
0.616 0.384 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.616 0.384 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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