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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs36183131
log Bayes Factor = 213.963
Chromosome 6   position 32,522,401  (GRCh37) Explore rs36183131 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.001 0.999
J44 Other chronic obstructive pulmonary disease
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.003 0.997
K70-K77 Diseases of liver
0.000 0.003 0.997
J33.9 Nasal polyp, unspecified
0.000 0.004 0.996
E14.3 With ophthalmic complications
0.000 0.004 0.996
J33 Nasal polyp
0.000 0.004 0.996
K51.3 Ulcerative (chronic) rectosigmoiditis
0.995 0.005 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.006 0.994
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.009 0.991
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.009 0.991
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.010 0.990
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.012 0.988
E70-E90 Metabolic disorders
0.000 0.012 0.987
K82 Other diseases of gallbladder
0.000 0.014 0.986
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.014 0.986
H43-H45 Disorders of vitreous body and globe
0.000 0.014 0.986
H40-H42 Glaucoma
0.000 0.015 0.985
K74 Fibrosis and cirrhosis of liver
0.000 0.015 0.985
K50-K52 Noninfective enteritis and colitis
0.004 0.017 0.978
J30-J39 Other diseases of upper respiratory tract
0.000 0.018 0.982
K82.8 Other specified diseases of gallbladder
0.000 0.019 0.981
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.019 0.981
E10.5 With peripheral circulatory complications
0.000 0.020 0.980
H43 Disorders of vitreous body
0.000 0.020 0.980
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.022 0.978
J33.8 Other polyp of sinus
0.000 0.023 0.977
H40 Glaucoma
0.000 0.025 0.975
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.026 0.974
E11.3 With ophthalmic complications
0.000 0.029 0.971
H40.9 Glaucoma, unspecified
0.000 0.030 0.970
K55-K64 Other diseases of intestines
0.000 0.032 0.968
K74.3 Primary biliary cirrhosis
0.000 0.034 0.966
L40-L45 Papulosquamous disorders
0.000 0.035 0.965
E11.1 With ketoacidosis
0.000 0.036 0.964
L43 Lichen planus
0.000 0.036 0.964
L43.9 Lichen planus, unspecified
0.000 0.037 0.963
E05.9 Thyrotoxicosis, unspecified
0.000 0.038 0.962
L40 Psoriasis
0.000 0.041 0.959
K51.8 Other ulcerative colitis
0.956 0.044 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.046 0.954
E06 Thyroiditis
0.000 0.046 0.954
K50 Crohn's disease [regional enteritis]
0.000 0.049 0.951
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.049 0.951
L40.5 Arthropathic psoriasis
0.000 0.049 0.951
K60 Fissure and fistula of anal and rectal regions
0.000 0.050 0.950
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.051 0.949
J46 Status asthmaticus
0.000 0.053 0.947
H43.3 Other vitreous opacities
0.000 0.053 0.947
J43 Emphysema
0.000 0.056 0.944
Chapter IX Diseases of the circulatory system
0.000 0.059 0.941
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.060 0.940
E10.2 With renal complications
0.000 0.061 0.939
I20-I25 Ischaemic heart diseases
0.000 0.061 0.939
K75 Other inflammatory liver diseases
0.000 0.064 0.936
H34 Retinal vascular occlusions
0.000 0.065 0.935
I10-I15 Hypertensive diseases
0.000 0.068 0.932
K72 Hepatic failure, not elsewhere classified
0.000 0.070 0.930
K58 Irritable bowel syndrome
0.000 0.071 0.929
M06.0 Seronegative rheumatoid arthritis
0.000 0.074 0.926
H43.8 Other disorders of vitreous body
0.000 0.077 0.923
E06.3 Autoimmune thyroiditis
0.000 0.077 0.923
J86 Pyothorax
0.000 0.079 0.921
I22 Subsequent myocardial infarction
0.000 0.082 0.918
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.082 0.918
E11.5 With peripheral circulatory complications
0.000 0.084 0.916
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.084 0.916
K86 Other diseases of pancreas
0.000 0.087 0.913
K60.2 Anal fissure, unspecified
0.000 0.089 0.911
K75.4 Autoimmune hepatitis
0.000 0.092 0.908
E07 Other disorders of thyroid
0.000 0.094 0.906
M07 Psoriatic and enteropathic arthropathies
0.000 0.099 0.901
E03.8 Other specified hypothyroidism
0.000 0.101 0.899
J43.9 Emphysema, unspecified
0.000 0.101 0.899
I10 Essential (primary) hypertension
0.000 0.101 0.899
K63 Other diseases of intestine
0.000 0.102 0.898
H40.1 Primary open-angle glaucoma
0.000 0.102 0.898
E13 Other specified diabetes mellitus
0.000 0.103 0.897
K60.0 Acute anal fissure
0.000 0.104 0.896
I20 Angina pectoris
0.000 0.104 0.896
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.107 0.893
K82.1 Hydrops of gallbladder
0.000 0.114 0.886
K81 Cholecystitis
0.000 0.116 0.884
E11.2 With renal complications
0.000 0.116 0.884
K51.2 Ulcerative (chronic) proctitis
0.880 0.120 0.000
K63.9 Disease of intestine, unspecified
0.000 0.120 0.880
K50.1 Crohn's disease of large intestine
0.000 0.123 0.877
M65-M68 Disorders of synovium and tendon
0.000 0.123 0.877
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.123 0.877
E11.6 With other specified complications
0.000 0.127 0.873
J86.9 Pyothorax without fistula
0.000 0.130 0.870
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.135 0.865
K74.5 Biliary cirrhosis, unspecified
0.000 0.137 0.863
H25-H28 Disorders of lens
0.000 0.144 0.856
M06.3 Rheumatoid nodule
0.000 0.147 0.853
K52 Other non-infective gastro-enteritis and colitis
0.001 0.148 0.852
E07.9 Disorder of thyroid, unspecified
0.000 0.148 0.852
K50.8 Other Crohn's disease
0.000 0.149 0.851
K81.1 Chronic cholecystitis
0.000 0.154 0.846
J33.0 Polyp of nasal cavity
0.000 0.156 0.844
K51.4 Pseudopolyposis of colon
0.838 0.162 0.000
I24 Other acute ischaemic heart diseases
0.000 0.163 0.837
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.164 0.836
K86.2 Cyst of pancreas
0.000 0.164 0.836
K73 Chronic hepatitis, not elsewhere classified
0.000 0.165 0.835
I12 Hypertensive renal disease
0.000 0.166 0.834
L40.9 Psoriasis, unspecified
0.000 0.166 0.834
K72.9 Hepatic failure, unspecified
0.000 0.167 0.833
I20.1 Angina pectoris with documented spasm
0.000 0.169 0.831
M70-M79 Other soft tissue disorders
0.000 0.169 0.831
H40.5 Glaucoma secondary to other eye disorders
0.000 0.170 0.830
M07.3 Other psoriatic arthropathies
0.000 0.170 0.830
K60.5 Anorectal fistula
0.000 0.172 0.828
E78.2 Mixed hyperlipidaemia
0.000 0.176 0.824
E13.9 Without complications
0.000 0.177 0.823
H34.8 Other retinal vascular occlusions
0.000 0.177 0.823
M65 Synovitis and tenosynovitis
0.000 0.178 0.822
G37.8 Other specified demyelinating diseases of central nervous system
0.822 0.178 0.000
K51.5 Mucosal proctocolitis
0.821 0.179 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.179 0.821
I20.9 Angina pectoris, unspecified
0.000 0.180 0.820
K63.3 Ulcer of intestine
0.000 0.181 0.819
J95-J99 Other diseases of the respiratory system
0.000 0.183 0.817
J86.0 Pyothorax with fistula
0.000 0.184 0.816
K55 Vascular disorders of intestine
0.000 0.185 0.815
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.186 0.814
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.191 0.809
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.804 0.196 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.199 0.801
E78.5 Hyperlipidaemia, unspecified
0.000 0.201 0.799
K72.0 Acute and subacute hepatic failure
0.000 0.201 0.799
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.201 0.799
E16.1 Other hypoglycaemia
0.000 0.203 0.797
I15 Secondary hypertension
0.000 0.206 0.794
H27 Other disorders of lens
0.000 0.207 0.793
K90.9 Intestinal malabsorption, unspecified
0.000 0.209 0.791
E40-E46 Malnutrition
0.000 0.212 0.788
E78.1 Pure hyperglyceridaemia
0.000 0.212 0.788
M14 Arthropathies in other diseases classified elsewhere
0.000 0.213 0.787
H34.2 Other retinal artery occlusions
0.000 0.214 0.786
E83 Disorders of mineral metabolism
0.690 0.215 0.096
E88 Other metabolic disorders
0.000 0.215 0.784
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.218 0.782
K50.0 Crohn's disease of small intestine
0.000 0.220 0.780
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.221 0.779
K52.1 Toxic gastro-enteritis and colitis
0.000 0.221 0.778
I20.0 Unstable angina
0.000 0.227 0.773
M77 Other enthesopathies
0.000 0.229 0.771
J37 Chronic laryngitis and laryngotracheitis
0.000 0.232 0.768
K86.1 Other chronic pancreatitis
0.000 0.233 0.767
K63.4 Enteroptosis
0.000 0.235 0.765
E11.0 With coma
0.000 0.235 0.765
L43.8 Other lichen planus
0.000 0.236 0.764
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.237 0.763
M77.1 Lateral epicondylitis
0.000 0.239 0.761
K62 Other diseases of anus and rectum
0.000 0.242 0.758
K74.6 Other and unspecified cirrhosis of liver
0.000 0.243 0.757
J32 Chronic sinusitis
0.000 0.244 0.756
K82.9 Disease of gallbladder, unspecified
0.000 0.244 0.756
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.246 0.754
H43.2 Crystalline deposits in vitreous body
0.000 0.248 0.752
K86.3 Pseudocyst of pancreas
0.000 0.252 0.748
H34.1 Central retinal artery occlusion
0.000 0.253 0.747
H43.9 Disorder of vitreous body, unspecified
0.000 0.255 0.745
I12.9 Hypertensive renal disease without renal failure
0.000 0.262 0.738
K82.3 Fistula of gallbladder
0.000 0.264 0.736
H25 Senile cataract
0.000 0.266 0.734
K75.9 Inflammatory liver disease, unspecified
0.000 0.266 0.734
K81.9 Cholecystitis, unspecified
0.000 0.268 0.732
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.269 0.731
Chapter VIII Diseases of the ear and mastoid process
0.000 0.269 0.731
H40.4 Glaucoma secondary to eye inflammation
0.000 0.270 0.730
H25.1 Senile nuclear cataract
0.000 0.271 0.729
J98 Other respiratory disorders
0.000 0.271 0.729
M11 Other crystal arthropathies
0.000 0.271 0.729
E11.8 With unspecified complications
0.000 0.271 0.728
E74 Other disorders of carbohydrate metabolism
0.000 0.271 0.728
K55.2 Angiodysplasia of colon
0.000 0.274 0.726
K82.2 Perforation of gallbladder
0.000 0.274 0.726
H30 Chorioretinal inflammation
0.000 0.277 0.723
K62.4 Stenosis of anus and rectum
0.000 0.280 0.720
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.281 0.719
L40.8 Other psoriasis
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.716
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.000
H60-H62 Diseases of external ear
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.715 0.284 0.000
G37.4 Subacute necrotising myelitis
0.715 0.284 0.000
G37.2 Central pontine myelinolysis
0.715 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.284 0.000
G37.0 Diffuse sclerosis
0.715 0.284 0.000
K62.1 Rectal polyp
0.000 0.285 0.715
K77 Liver disorders in diseases classified elsewhere
0.000 0.285 0.714
K71 Toxic liver disease
0.000 0.285 0.714
H43.1 Vitreous haemorrhage
0.000 0.286 0.714
J33.1 Polypoid sinus degeneration
0.000 0.286 0.714
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.286 0.714
M06.34 Rheumatoid nodule (Hand)
0.000 0.287 0.713
M75 Shoulder lesions
0.000 0.287 0.713
J43.2 Centrilobular emphysema
0.000 0.288 0.712
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.290 0.710
E78.6 Lipoprotein deficiency
0.000 0.290 0.710
E78.3 Hyperchylomicronaemia
0.000 0.290 0.710
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.290 0.710
E77 Disorders of glycoprotein metabolism
0.000 0.292 0.708
E76 Disorders of glycosaminoglycan metabolism
0.000 0.292 0.708
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.292 0.708
E72 Other disorders of amino-acid metabolism
0.000 0.292 0.708
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.292 0.708
E70 Disorders of aromatic amino-acid metabolism
0.000 0.292 0.708
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.292 0.708
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.293 0.707
H42 Glaucoma in diseases classified elsewhere
0.000 0.294 0.706
K74.4 Secondary biliary cirrhosis
0.000 0.294 0.706
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.294 0.706
K74.1 Hepatic sclerosis
0.000 0.294 0.706
I25 Chronic ischaemic heart disease
0.000 0.297 0.703
H43.0 Vitreous prolapse
0.000 0.298 0.702
J41 Simple and mucopurulent chronic bronchitis
0.000 0.299 0.701
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.299 0.701
K55.8 Other vascular disorders of intestine
0.000 0.300 0.700
H40.6 Glaucoma secondary to drugs
0.000 0.301 0.699
H40.3 Glaucoma secondary to eye trauma
0.000 0.301 0.699
E05.5 Thyroid crisis or storm
0.000 0.301 0.698
E05.4 Thyrotoxicosis factitia
0.000 0.301 0.698
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.301 0.698
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.301 0.698
J98.4 Other disorders of lung
0.000 0.303 0.697
H61 Other disorders of external ear
0.000 0.303 0.697
K73.9 Chronic hepatitis, unspecified
0.000 0.304 0.696
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.306 0.694
M75.0 Adhesive capsulitis of shoulder
0.000 0.306 0.694
K51.0 Ulcerative (chronic) enterocolitis
0.693 0.307 0.000
I23 Certain current complications following acute myocardial infarction
0.000 0.308 0.692
L44 Other papulosquamous disorders
0.000 0.308 0.692
L41 Parapsoriasis
0.000 0.308 0.692
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.308 0.692
H27.0 Aphakia
0.000 0.309 0.691
L43.3 Subacute (active) lichen planus
0.000 0.309 0.691
L43.2 Lichenoid drug reaction
0.000 0.309 0.691
L43.1 Bullous lichen planus
0.000 0.309 0.691
L43.0 Hypertrophic lichen planus
0.000 0.309 0.691
L40.4 Guttate psoriasis
0.000 0.313 0.687
L40.3 Pustulosis palmaris et plantaris
0.000 0.313 0.687
L40.2 Acrodermatitis continua
0.000 0.313 0.687
L40.1 Generalised pustular psoriasis
0.000 0.313 0.687
M14.6 Neuropathic arthropathy
0.000 0.313 0.687
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.314 0.686
K63.2 Fistula of intestine
0.000 0.314 0.685
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.315 0.685
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.316 0.684
E06.5 Other chronic thyroiditis
0.000 0.316 0.684
E06.4 Drug-induced thyroiditis
0.000 0.316 0.684
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.316 0.684
E06.1 Subacute thyroiditis
0.000 0.316 0.684
E06.0 Acute thyroiditis
0.000 0.316 0.684
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.317 0.683
I11 Hypertensive heart disease
0.000 0.319 0.681
M12 Other specific arthropathies
0.000 0.319 0.680
H27.8 Other specified disorders of lens
0.000 0.320 0.680
J43.8 Other emphysema
0.000 0.323 0.677
J43.1 Panlobular emphysema
0.000 0.323 0.677
J43.0 MacLeod's syndrome
0.000 0.323 0.677
I00-I02 Acute rheumatic fever
0.000 0.325 0.674
K86.8 Other specified diseases of pancreas
0.000 0.327 0.672
E11.4 With neurological complications
0.000 0.328 0.672
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.329 0.671
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.329 0.671
K75.2 Nonspecific reactive hepatitis
0.000 0.329 0.671
K75.1 Phlebitis of portal vein
0.000 0.329 0.671
H34.0 Transient retinal artery occlusion
0.000 0.330 0.670
I15.1 Hypertension secondary to other renal disorders
0.000 0.331 0.669
I13 Hypertensive heart and renal disease
0.000 0.331 0.668
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.333 0.667
K72.1 Chronic hepatic failure
0.000 0.333 0.666
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.334 0.666
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.334 0.666
M72 Fibroblastic disorders
0.000 0.335 0.665
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.336 0.664
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.336 0.664
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.336 0.664
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.336 0.664
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.336 0.664
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.336 0.664
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.336 0.664
E84 Cystic fibrosis
0.000 0.336 0.663
H34.9 Retinal vascular occlusion, unspecified
0.000 0.337 0.663
I12.0 Hypertensive renal disease with renal failure
0.000 0.339 0.661
E06.9 Thyroiditis, unspecified
0.000 0.339 0.661
H61.0 Perichondritis of external ear
0.000 0.340 0.660
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.340 0.660
M66 Spontaneous rupture of synovium and tendon
0.000 0.343 0.656
E05.8 Other thyrotoxicosis
0.000 0.345 0.655
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.345 0.655
K50.9 Crohn's disease, unspecified
0.000 0.346 0.654
J42 Unspecified chronic bronchitis
0.000 0.347 0.653
I25.5 Ischaemic cardiomyopathy
0.000 0.349 0.651
M75.2 Bicipital tendinitis
0.000 0.349 0.651
K82.0 Obstruction of gallbladder
0.000 0.350 0.650
E07.1 Dyshormogenetic goitre
0.000 0.350 0.650
E07.0 Hypersecretion of calcitonin
0.000 0.350 0.650
L42 Pityriasis rosea
0.000 0.351 0.649
M07.6 Other enteropathic arthropathies
0.000 0.354 0.646
M07.5 Arthropathy in ulcerative colitis
0.000 0.354 0.646
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.354 0.646
M07.2 Psoriatic spondylitis
0.000 0.354 0.646
M07.1 Arthritis mutilans
0.000 0.354 0.646
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.354 0.646
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.356 0.644
E13.8 With unspecified complications
0.000 0.357 0.643
E13.7 With multiple complications
0.000 0.357 0.643
E13.6 With other specified complications
0.000 0.357 0.643
E13.5 With peripheral circulatory complications
0.000 0.357 0.643
E13.4 With neurological complications
0.000 0.357 0.643
E13.3 With ophthalmic complications
0.000 0.357 0.643
E13.2 With renal complications
0.000 0.357 0.643
E13.1 With ketoacidosis
0.000 0.357 0.643
E13.0 With coma
0.000 0.357 0.643
E79 Disorders of purine and pyrimidine metabolism
0.000 0.359 0.641
E78.8 Other disorders of lipoprotein metabolism
0.000 0.360 0.640
K62.0 Anal polyp
0.000 0.361 0.639
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.362 0.638
E46 Unspecified protein-energy malnutrition
0.000 0.364 0.636
M10 Gout
0.000 0.364 0.636
K60.1 Chronic anal fissure
0.000 0.367 0.633
J32.9 Chronic sinusitis, unspecified
0.000 0.368 0.632
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.371 0.629
E83.3 Disorders of phosphorus metabolism
0.596 0.372 0.032
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.372 0.628
L10-L14 Bullous disorders
0.000 0.373 0.627
K81.8 Other cholecystitis
0.000 0.377 0.623
K90.8 Other intestinal malabsorption
0.000 0.377 0.623
M65.1 Other infective (teno)synovitis
0.000 0.378 0.622
E83.9 Disorder of mineral metabolism, unspecified
0.565 0.379 0.056
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.380 0.620
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.380 0.620
K75.8 Other specified inflammatory liver diseases
0.000 0.380 0.620
J32.4 Chronic pansinusitis
0.000 0.380 0.620
E03.1 Congenital hypothyroidism without goitre
0.000 0.382 0.618
K74.0 Hepatic fibrosis
0.000 0.384 0.616
I15.9 Seconday hypertension, unspecified
0.000 0.385 0.615
J37.0 Chronic laryngitis
0.000 0.385 0.615
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.386 0.614
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.388 0.612
M06.38 Rheumatoid nodule (Other)
0.000 0.388 0.612
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.388 0.612
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.388 0.612
M06.33 Rheumatoid nodule (Forearm)
0.000 0.388 0.612
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.388 0.612
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.388 0.612
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.388 0.612
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.389 0.611
K62.7 Radiation proctitis
0.000 0.390 0.610
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.392 0.608
K55.1 Chronic vascular disorders of intestine
0.000 0.392 0.608
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.001 0.393 0.607
J85 Abscess of lung and mediastinum
0.000 0.394 0.606
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.396 0.604
H60 Otitis externa
0.000 0.399 0.601
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.401 0.599
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.401 0.599
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.401 0.599
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.401 0.599
E73 Lactose intolerance
0.000 0.402 0.598
L40.0 Psoriasis vulgaris
0.000 0.403 0.597
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.404 0.596
H27.1 Dislocation of lens
0.000 0.404 0.596
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.404 0.596
M07.38 Other psoriatic arthropathies (Other)
0.000 0.405 0.595
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.405 0.595
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.405 0.595
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.405 0.595
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.405 0.595
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.405 0.595
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.405 0.595
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.000 0.405 0.595
E88.2 Lipomatosis, not elsewhere classified
0.000 0.405 0.595
M65.2 Calcific tendinitis
0.000 0.410 0.590
M65.0 Abscess of tendon sheath
0.000 0.410 0.590
I25.2 Old myocardial infarction
0.000 0.411 0.589
J98.6 Disorders of diaphragm
0.000 0.411 0.589
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.411 0.589
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.411 0.589
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.411 0.589
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.411 0.589
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.411 0.589
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.411 0.589
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.411 0.589
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.411 0.589
E07.8 Other specified disorders of thyroid
0.000 0.412 0.588
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.413 0.587
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.414 0.586
J96 Respiratory failure, not elsewhere classified
0.000 0.414 0.585
M45-M49 Spondylopathies
0.000 0.415 0.585
H61.8 Other specified disorders of external ear
0.000 0.419 0.581
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.420 0.580
E85 Amyloidosis
0.000 0.421 0.579
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.422 0.578
H61.3 Acquired stenosis of external ear canal
0.000 0.423 0.577
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.425 0.575
J60-J70 Lung diseases due to external agents
0.000 0.429 0.571
K60.4 Rectal fistula
0.000 0.431 0.569

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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