TreeWAS – Variant ID: rs362521

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
L40-L45 Papulosquamous disorders	0.999	0.001	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.997	0.003	0.000
Chapter VI Diseases of the nervous system	0.995	0.005	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.006	0.994
M05-M14 Inflammatory polyarthropathies	0.991	0.009	0.000
M07 Psoriatic and enteropathic arthropathies	0.990	0.010	0.000
M07.3 Other psoriatic arthropathies	0.990	0.010	0.000
Chapter II Neoplasms	0.985	0.015	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.976	0.024	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.969	0.031	0.000
M86-M90 Other osteopathies	0.968	0.032	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.959	0.041	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.950	0.050	0.000
Chapter XIV Diseases of the genitourinary system	0.950	0.050	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.946	0.054	0.000
K90.0 Coeliac disease	0.000	0.057	0.943
Chapter V Mental and behavioural disorders	0.940	0.060	0.000
D00-D09 In situ neoplasms	0.936	0.064	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.931	0.069	0.000
N10-N16 Renal tubulo-interstitial diseases	0.931	0.069	0.000
N13 Obstructive and reflux uropathy	0.925	0.075	0.000
L40.0 Psoriasis vulgaris	0.925	0.075	0.000
N20-N23 Urolithiasis	0.923	0.077	0.000
G20-G26 Extrapyramidal and movement disorders	0.923	0.077	0.000
T43.2 Other and unspecified antidepressants	0.921	0.079	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.914	0.086	0.000
M60-M63 Disorders of muscles	0.912	0.088	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.912	0.088	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.911	0.089	0.000
M89 Other disorders of bone	0.909	0.091	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.908	0.092	0.000
G40-G47 Episodic and paroxysmal disorders	0.905	0.095	0.000
C79 Secondary malignant neoplasm of other sites	0.899	0.101	0.000
F30-F39 Mood [affective] disorders	0.898	0.102	0.000
G40 Epilepsy	0.896	0.104	0.000
N20 Calculus of kidney and ureter	0.894	0.106	0.000
E03 Other hypothyroidism	0.000	0.108	0.892
C15-C26 Malignant neoplasms of digestive organs	0.891	0.109	0.000
L57.0 Actinic keratosis	0.881	0.119	0.000
N60-N64 Disorders of breast	0.880	0.120	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.870	0.130	0.000
S60-S69 Injuries to the wrist and hand	0.869	0.131	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.868	0.132	0.000
G35 Multiple sclerosis	0.867	0.133	0.000
S40-S49 Injuries to the shoulder and upper arm	0.866	0.134	0.000
M89.9 Disorder of bone, unspecified	0.865	0.135	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.864	0.136	0.000
N20.1 Calculus of ureter	0.862	0.138	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.857	0.143	0.000
G70-G73 Diseases of myoneural junction and muscle	0.852	0.148	0.000
G30-G32 Other degenerative diseases of the nervous system	0.851	0.149	0.000
M70-M79 Other soft tissue disorders	0.850	0.150	0.000
M62 Other disorders of muscle	0.850	0.150	0.000
G37 Other demyelinating diseases of central nervous system	0.849	0.151	0.000
M10 Gout	0.846	0.154	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.843	0.157	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.842	0.158	0.000
N63 Unspecified lump in breast	0.839	0.161	0.000
M91-M94 Chondropathies	0.838	0.162	0.000
N13.3 Other and unspecified hydronephrosis	0.836	0.164	0.000
C18 Malignant neoplasm of colon	0.832	0.168	0.000
F31 Bipolar affective disorder	0.829	0.171	0.000
S62 Fracture at wrist and hand level	0.829	0.171	0.000
C44 Other malignant neoplasms of skin	0.827	0.173	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.826	0.174	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.825	0.175	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.825	0.175	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.821	0.179	0.000
S90-S99 Injuries to the ankle and foot	0.818	0.181	0.000
G40.9 Epilepsy, unspecified	0.818	0.182	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.818	0.182	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.817	0.183	0.000
T18 Foreign body in alimentary tract	0.813	0.187	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.813	0.187	0.000
E00-E07 Disorders of thyroid gland	0.000	0.189	0.811
T36 Poisoning by systemic antibiotics	0.810	0.190	0.000
M45-M49 Spondylopathies	0.810	0.190	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.810	0.190	0.000
M87 Osteonecrosis	0.810	0.190	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.807	0.193	0.000
F30 Manic episode	0.806	0.194	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.806	0.194	0.000
M62.8 Other specified disorders of muscle	0.805	0.195	0.000
N64 Other disorders of breast	0.803	0.197	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.801	0.199	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.800	0.200	0.000
M00-M03 Infectious arthropathies	0.799	0.201	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.798	0.202	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.795	0.204	0.000
D04 Carcinoma in situ of skin	0.794	0.206	0.000
M50-M54 Other dorsopathies	0.794	0.206	0.000
S10-S19 Injuries to the neck	0.793	0.207	0.000
N20.0 Calculus of kidney	0.793	0.207	0.000
N13.4 Hydroureter	0.792	0.208	0.000
G20 Parkinson's disease	0.791	0.209	0.000
D05 Carcinoma in situ of breast	0.789	0.211	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.789	0.211	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.789	0.211	0.000
N13.6 Pyonephrosis	0.786	0.214	0.000
G24 Dystonia	0.786	0.214	0.000
C78.7 Secondary malignant neoplasm of liver	0.786	0.214	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.776	0.224	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.776	0.224	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.776	0.224	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.774	0.226	0.000
L40.8 Other psoriasis	0.773	0.227	0.000
M90 Osteopathies in diseases classified elsewhere	0.770	0.230	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.768	0.232	0.000
N21 Calculus of lower urinary tract	0.765	0.235	0.000
M50 Cervical disk disorders	0.765	0.235	0.000
M77 Other enthesopathies	0.764	0.235	0.000
G70 Myasthenia gravis and other myoneural disorders	0.764	0.236	0.000
T39.1 4-Aminophenol derivatives	0.758	0.242	0.000
S31 Open wound of abdomen, lower back and pelvis	0.758	0.242	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.757	0.243	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.756	0.244	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.753	0.247	0.000
S62.3 Fracture of other metacarpal bone	0.753	0.247	0.000
T45.0 Antiallergic and antiemetic drugs	0.753	0.247	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.752	0.248	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.752	0.248	0.000
M50.3 Other cervical disk degeneration	0.751	0.249	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.751	0.249	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.750	0.250	0.000
S92 Fracture of foot, except ankle	0.750	0.250	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.250	0.749
N13.5 Kinking and stricture of ureter without hydronephrosis	0.749	0.250	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.749	0.251	0.000
M46 Other inflammatory spondylopathies	0.748	0.252	0.000
G62 Other polyneuropathies	0.747	0.253	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.747	0.253	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.746	0.254	0.000
C64-C68 Malignant neoplasms of urinary tract	0.746	0.254	0.000
C17 Malignant neoplasm of small intestine	0.746	0.254	0.000
T17 Foreign body in respiratory tract	0.745	0.255	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.744	0.256	0.000
Chapter I Certain infectious and parasitic diseases	0.743	0.257	0.000
M10.9 Gout, unspecified	0.742	0.258	0.000
N64.5 Other signs and symptoms in breast	0.739	0.261	0.000
S32 Fracture of lumbar spine and pelvis	0.738	0.262	0.000
C18.6 Descending colon	0.738	0.262	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.737	0.263	0.000
N61 Inflammatory disorders of breast	0.731	0.269	0.000
N11 Chronic tubulo-interstitial nephritis	0.730	0.270	0.000
G25 Other extrapyramidal and movement disorders	0.728	0.272	0.000
C44.0 Skin of lip	0.725	0.275	0.000
C18.7 Sigmoid colon	0.725	0.275	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.723	0.277	0.000
M94 Other disorders of cartilage	0.722	0.278	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.722	0.278	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.722	0.278	0.000
F80-F89 Disorders of psychological development	0.721	0.279	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.720	0.280	0.000
N17-N19 Renal failure	0.720	0.280	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.719	0.281	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.718	0.282	0.000
M86 Osteomyelitis	0.718	0.282	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
L44 Other papulosquamous disorders	0.716	0.283	0.000
L41 Parapsoriasis	0.716	0.283	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.716	0.283	0.000
L42 Pityriasis rosea	0.716	0.283	0.000
L10-L14 Bullous disorders	0.716	0.283	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.716	0.284	0.000
T33-T35 Frostbite	0.716	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284	0.000
C02.9 Tongue, unspecified	0.715	0.285	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.715	0.285	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.715	0.285	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.715	0.285	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.715	0.285	0.000
S62.6 Fracture of other finger	0.714	0.286	0.000
F60-F69 Disorders of adult personality and behaviour	0.713	0.287	0.000
D03 Melanoma in situ	0.713	0.287	0.000
C44.7 Skin of lower limb, including hip	0.713	0.287	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.712	0.288	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.712	0.288	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.288	0.712
T00-T07 Injuries involving multiple body regions	0.711	0.288	0.000
F99-F99 Unspecified mental disorder	0.711	0.289	0.000
C44.5 Skin of trunk	0.711	0.289	0.000
M12 Other specific arthropathies	0.711	0.289	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.711	0.289	0.000
M08 Juvenile arthritis	0.711	0.289	0.000
G41 Status epilepticus	0.710	0.289	0.000
M07.6 Other enteropathic arthropathies	0.710	0.290	0.000
M07.5 Arthropathy in ulcerative colitis	0.710	0.290	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.710	0.290	0.000
M07.2 Psoriatic spondylitis	0.710	0.290	0.000
M07.1 Arthritis mutilans	0.710	0.290	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.710	0.290	0.000
M07.38 Other psoriatic arthropathies (Other)	0.710	0.290	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.710	0.290	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.710	0.290	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.710	0.290	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.710	0.290	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.710	0.290	0.000
M89.3 Hypertrophy of bone	0.710	0.290	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.709	0.291	0.000
M40-M43 Deforming dorsopathies	0.708	0.292	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.706	0.294	0.000
C18.9 Colon, unspecified	0.704	0.296	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.703	0.297	0.000
C12 Malignant neoplasm of pyriform sinus	0.702	0.298	0.000
C10 Malignant neoplasm of oropharynx	0.701	0.299	0.000
G70.0 Myasthenia gravis	0.701	0.299	0.000
M88 Paget's disease of bone [osteitis deformans]	0.701	0.299	0.000
M62.88 Other specified disorders of muscle (Other)	0.700	0.300	0.000
S37 Injury of urinary and pelvic organs	0.699	0.301	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.699	0.301	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.698	0.302	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.698	0.302	0.000
T39.0 Salicylates	0.698	0.302	0.000
M14 Arthropathies in other diseases classified elsewhere	0.698	0.302	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.697	0.303	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.697	0.303	0.000
D04.4 Skin of scalp and neck	0.696	0.304	0.000
L60-L75 Disorders of skin appendages	0.696	0.304	0.000
Chapter XX External causes of morbidity and mortality	0.696	0.304	0.000
N20.9 Urinary calculus, unspecified	0.695	0.305	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.695	0.305	0.000
T43.9 Psychotropic drug, unspecified	0.695	0.305	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.695	0.305	0.000
T43.6 Psychostimulants with abuse potential	0.695	0.305	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.695	0.305	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.694	0.306	0.000
C78.0 Secondary malignant neoplasm of lung	0.693	0.307	0.000
F30.9 Manic episode, unspecified	0.693	0.307	0.000
F30.2 Mania with psychotic symptoms	0.692	0.308	0.000
S41 Open wound of shoulder and upper arm	0.691	0.309	0.000
M80-M85 Disorders of bone density and structure	0.689	0.311	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.689	0.311	0.000
C44.4 Skin of scalp and neck	0.687	0.313	0.000
M71 Other bursopathies	0.684	0.316	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.684	0.316	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.684	0.316	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.683	0.317	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.683	0.317	0.000
M89.5 Osteolysis	0.682	0.318	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.682	0.318	0.000
G36 Other acute disseminated demyelination	0.681	0.318	0.000
S00-S09 Injuries to the head	0.682	0.318	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.681	0.319	0.000
S60 Superficial injury of wrist and hand	0.681	0.319	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.680	0.320	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.680	0.320	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.680	0.320	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.678	0.322	0.000
L58 Radiodermatitis	0.678	0.322	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.678	0.322	0.000
L55 Sunburn	0.678	0.322	0.000
Chapter XXII Codes for special purposes	0.678	0.322	0.000
N25-N29 Other disorders of kidney and ureter	0.678	0.322	0.000
D07.5 Prostate	0.677	0.323	0.000
C09 Malignant neoplasm of tonsil	0.676	0.323	0.000
D07.1 Vulva	0.677	0.323	0.000
T36.0 Penicillins	0.676	0.323	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.676	0.324	0.000
T16 Foreign body in ear	0.676	0.324	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.676	0.324	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.675	0.325	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.674	0.326	0.000
F39 Unspecified mood [affective] disorder	0.674	0.326	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.674	0.326	0.000
F70-F79 Mental retardation	0.674	0.326	0.000
T18.1 Foreign body in oesophagus	0.673	0.327	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.671	0.329	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.671	0.329	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.671	0.329	0.000
D06 Carcinoma in situ of cervix uteri	0.670	0.330	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.670	0.330	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.669	0.331	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.668	0.331	0.000
M87.9 Osteonecrosis, unspecified	0.668	0.332	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.668	0.332	0.000
C02.4 Lingual tonsil	0.668	0.332	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.668	0.332	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.668	0.332	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.667	0.332	0.000
N15 Other renal tubulo-interstitial diseases	0.667	0.332	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.667	0.332	0.000
S65 Injury of blood vessels at wrist and hand level	0.667	0.333	0.000
E06 Thyroiditis	0.000	0.333	0.666
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.666	0.334	0.000
S67 Crushing injury of wrist and hand	0.665	0.335	0.000
E03.8 Other specified hypothyroidism	0.000	0.335	0.664
N13.7 Vesicoureteral-reflux-associated uropathy	0.663	0.337	0.000
C16 Malignant neoplasm of stomach	0.662	0.338	0.000
A30-A49 Other bacterial diseases	0.662	0.338	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.662	0.338	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.662	0.338	0.000
G23 Other degenerative diseases of basal ganglia	0.662	0.338	0.000
G21 Secondary Parkinsonism	0.662	0.338	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.662	0.338	0.000
G22 Parkinsonism in diseases classified elsewhere	0.662	0.338	0.000
N21.0 Calculus in bladder	0.660	0.340	0.000
C04 Malignant neoplasm of floor of mouth	0.659	0.341	0.000
M10.99 Gout, unspecified (Site unspecified)	0.658	0.342	0.000
C18.1 Appendix	0.658	0.342	0.000
C34 Malignant neoplasm of bronchus and lung	0.658	0.342	0.000
C44.3 Skin of other and unspecified parts of face	0.656	0.344	0.000
M00 Pyogenic arthritis	0.655	0.344	0.000
T19 Foreign body in genito-urinary tract	0.655	0.345	0.000
T15 Foreign body on external eye	0.655	0.345	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.654	0.346	0.000
M61 Calcification and ossification of muscle	0.654	0.346	0.000
M60 Myositis	0.654	0.346	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.654	0.346	0.000
C13 Malignant neoplasm of hypopharynx	0.654	0.346	0.000
C11 Malignant neoplasm of nasopharynx	0.654	0.346	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.654	0.346	0.000
C05 Malignant neoplasm of palate	0.654	0.346	0.000
C03 Malignant neoplasm of gum	0.654	0.346	0.000
C00 Malignant neoplasm of lip	0.654	0.346	0.000
A49 Bacterial infection of unspecified site	0.654	0.346	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.653	0.347	0.000
S36 Injury of intra-abdominal organs	0.653	0.347	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.653	0.347	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.653	0.347	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.653	0.347	0.000
S62.2 Fracture of first metacarpal bone	0.653	0.347	0.000
N00-N08 Glomerular diseases	0.653	0.347	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.652	0.348	0.000
M89.6 Osteopathy after poliomyelitis	0.652	0.348	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.652	0.348	0.000
M89.2 Other disorders of bone development and growth	0.652	0.348	0.000
M89.1 Epiphyseal arrest	0.652	0.348	0.000
M89.0 Algoneurodystrophy	0.652	0.348	0.000
M53 Other dorsopathies, not elsewhere classified	0.651	0.349	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.651	0.349	0.000
L57.5 Actinic granuloma	0.651	0.349	0.000
L57.4 Cutis laxa senilis	0.651	0.349	0.000
L57.3 Poikiloderma of Civatte	0.651	0.349	0.000
L57.2 Cutis rhomboidalis nuchae	0.651	0.349	0.000
L57.1 Actinic reticuloid	0.651	0.349	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.651	0.349	0.000
F23 Acute and transient psychotic disorders	0.650	0.350	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.650	0.350	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.649	0.351	0.000
W20-W49 Exposure to inanimate mechanical forces	0.647	0.353	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.646	0.354	0.000
N13.8 Other obstructive and reflux uropathy	0.645	0.354	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.644	0.356	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.644	0.356	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.644	0.356	0.000
F38 Other mood [affective] disorders	0.644	0.356	0.000
F34 Persistent mood [affective] disorders	0.644	0.356	0.000
N17 Acute renal failure	0.644	0.356	0.000
G24.9 Dystonia, unspecified	0.643	0.357	0.000
A49.0 Staphylococcal infection, unspecified	0.643	0.357	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.642	0.357	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.642	0.357	0.000
C17.0 Duodenum	0.641	0.359	0.000
S64 Injury of nerves at wrist and hand level	0.641	0.359	0.000
C24.0 Extrahepatic bile duct	0.641	0.359	0.000
T79-T79 Certain early complications of trauma	0.640	0.360	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.640	0.360	0.000
E03.5 Myxoedema coma	0.000	0.360	0.639
E03.4 Atrophy of thyroid (acquired)	0.000	0.360	0.639
E03.3 Postinfectious hypothyroidism	0.000	0.360	0.639
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.360	0.639
E03.1 Congenital hypothyroidism without goitre	0.000	0.360	0.639
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.360	0.639
M72 Fibroblastic disorders	0.638	0.362	0.000
C24.9 Biliary tract, unspecified	0.638	0.362	0.000
C06.0 Cheek mucosa	0.637	0.363	0.000
N64.8 Other specified disorders of breast	0.637	0.363	0.000
S31.4 Open wound of vagina and vulva	0.636	0.364	0.000
L50-L54 Urticaria and erythema	0.635	0.365	0.000
G62.0 Drug-induced polyneuropathy	0.635	0.365	0.000
N23 Unspecified renal colic	0.635	0.365	0.000
G31.8 Other specified degenerative diseases of nervous system	0.635	0.365	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.633	0.366	0.000
G24.5 Blepharospasm	0.633	0.367	0.000
C01 Malignant neoplasm of base of tongue	0.631	0.369	0.000
S43.0 Dislocation of shoulder joint	0.631	0.369	0.000
M76 Enthesopathies of lower limb, excluding foot	0.630	0.370	0.000
M11 Other crystal arthropathies	0.630	0.370	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.629	0.371	0.000
M90.7 Fracture of bone in neoplastic disease	0.628	0.372	0.000
S92.0 Fracture of calcaneus	0.628	0.372	0.000
C44.2 Skin of ear and external auricular canal	0.626	0.374	0.000
S19 Other and unspecified injuries of neck	0.626	0.374	0.000
M87.2 Osteonecrosis due to previous trauma	0.626	0.374	0.000
Q78 Other osteochondrodysplasias	0.625	0.375	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.625	0.375	0.000
C90.0 Multiple myeloma	0.625	0.375	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.624	0.376	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.624	0.376	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.624	0.376	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.624	0.376	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.624	0.376	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.624	0.376	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.624	0.376	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.624	0.376	0.000
T44.0 Anticholinesterase agents	0.624	0.376	0.000
M79.1 Myalgia	0.624	0.376	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.377	0.623
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.623	0.377	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.622	0.377	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.622	0.378	0.000
T45.8 Other primarily systemic and haematological agents	0.622	0.378	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.622	0.378	0.000
T45.6 Fibrinolysis-affecting drugs	0.622	0.378	0.000
T45.5 Anticoagulants	0.622	0.378	0.000
T45.4 Iron and its compounds	0.622	0.378	0.000
T45.3 Enzymes, not elsewhere classified	0.622	0.378	0.000
T45.2 Vitamins, not elsewhere classified	0.622	0.378	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.622	0.378	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.621	0.378	0.000
G40.5 Special epileptic syndromes	0.621	0.379	0.000
S48 Traumatic amputation of shoulder and upper arm	0.621	0.379	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.621	0.379	0.000
S44 Injury of nerves at shoulder and upper arm level	0.621	0.379	0.000
S47 Crushing injury of shoulder and upper arm	0.621	0.379	0.000
M77.1 Lateral epicondylitis	0.621	0.379	0.000
S69 Other and unspecified injuries of wrist and hand	0.620	0.379	0.000
S92.1 Fracture of talus	0.620	0.380	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.620	0.380	0.000
M89.98 Disorder of bone, unspecified (Other)	0.620	0.380	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.620	0.380	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.620	0.380	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.620	0.380	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.620	0.380	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.620	0.380	0.000
S10 Superficial injury of neck	0.619	0.381	0.000
S02 Fracture of skull and facial bones	0.619	0.381	0.000
C18.3 Hepatic flexure	0.618	0.382	0.000
M77.0 Medial epicondylitis	0.618	0.382	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.616	0.384	0.000
C23 Malignant neoplasm of gallbladder	0.616	0.384	0.000
D04.6 Skin of upper limb, including shoulder	0.615	0.385	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.615	0.385	0.000
T39.4 Antirheumatics, not elsewhere classified	0.615	0.385	0.000
T39.2 Pyrazolone derivatives	0.615	0.385	0.000
T17.2 Foreign body in pharynx	0.615	0.385	0.000
F32 Depressive episode	0.615	0.385	0.000
C79.6 Secondary malignant neoplasm of ovary	0.614	0.386	0.000
W22 Striking against or struck by other objects	0.614	0.386	0.000
C20 Malignant neoplasm of rectum	0.613	0.387	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.613	0.387	0.000
C60-C63 Malignant neoplasms of male genital organs	0.612	0.387	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.611	0.389	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.610	0.390	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.610	0.390	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.609	0.390	0.000
M62.9 Disorder of muscle, unspecified	0.609	0.391	0.000
M62.6 Muscle strain	0.609	0.391	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.609	0.391	0.000
M62.4 Contracture of muscle	0.609	0.391	0.000
M62.3 Immobility syndrome (paraplegic)	0.609	0.391	0.000
M62.2 Ischaemic infarction of muscle	0.609	0.391	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.609	0.391	0.000
M62.0 Diastasis of muscle	0.609	0.391	0.000
S63.6 Sprain and strain of finger(s)	0.609	0.391	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.609	0.391	0.000
G37.5 Concentric sclerosis [Balo]	0.609	0.391	0.000
G37.4 Subacute necrotising myelitis	0.609	0.391	0.000
G37.2 Central pontine myelinolysis	0.609	0.391	0.000
G37.1 Central demyelination of corpus callosum	0.609	0.391	0.000
G37.0 Diffuse sclerosis	0.609	0.391	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.608	0.392	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.608	0.392	0.000
S62.61 Fracture of other finger (open)	0.608	0.392	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.608	0.392	0.000
B35-B49 Mycoses	0.607	0.392	0.000
T23 Burn and corrosion of wrist and hand	0.607	0.392	0.000
M47 Spondylosis	0.607	0.393	0.000
M10.4 Other secondary gout	0.607	0.393	0.000
M10.3 Gout due to impairment of renal function	0.607	0.393	0.000
M10.2 Drug-induced gout	0.607	0.393	0.000
M10.1 Lead-induced gout	0.607	0.393	0.000
M10.0 Idiopathic gout	0.607	0.393	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.607	0.393	0.000
T46.1 Calcium-channel blockers	0.606	0.393	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.606	0.394	0.000
M92 Other juvenile osteochondrosis	0.606	0.394	0.000
S62.7 Multiple fractures of fingers	0.606	0.394	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.606	0.394	0.000
Q76 Congenital malformations of spine and bony thorax	0.606	0.394	0.000
Q80-Q89 Other congenital malformations	0.605	0.395	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.605	0.395	0.000
D05.1 Intraductal carcinoma in situ	0.605	0.395	0.000
M94.8 Other specified disorders of cartilage	0.604	0.395	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.604	0.396	0.000
G64 Other disorders of peripheral nervous system	0.604	0.396	0.000
C18.5 Splenic flexure	0.603	0.396	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.603	0.397	0.000
S42 Fracture of shoulder and upper arm	0.602	0.398	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations