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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs37004
log Bayes Factor = 36.028
Chromosome 5   position 1,356,684  (GRCh37) Explore rs37004 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
N42 Other disorders of prostate
0.000 0.000 1.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
Chapter II Neoplasms
0.000 0.000 1.000
C64-C68 Malignant neoplasms of urinary tract
0.000 0.000 1.000
C67 Malignant neoplasm of bladder
0.000 0.000 1.000
C44.5 Skin of trunk
0.000 0.000 1.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.000 1.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.000 1.000
N42.9 Disorder of prostate, unspecified
0.000 0.001 0.999
C34 Malignant neoplasm of bronchus and lung
0.000 0.001 0.999
N40-N51 Diseases of male genital organs
0.000 0.001 0.999
N42.8 Other specified disorders of prostate
0.000 0.002 0.998
C67.9 Bladder, unspecified
0.000 0.002 0.998
C44.1 Skin of eyelid, including canthus
0.000 0.002 0.998
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.003 0.997
N41 Inflammatory diseases of prostate
0.000 0.004 0.996
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.005 0.995
C79 Secondary malignant neoplasm of other sites
0.000 0.006 0.994
C44.6 Skin of upper limb, including shoulder
0.000 0.007 0.993
C34.9 Bronchus or lung, unspecified
0.000 0.007 0.993
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.008 0.992
C67.4 Posterior wall of bladder
0.000 0.008 0.992
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.000 0.012 0.988
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.017 0.983
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.022 0.978
C44.7 Skin of lower limb, including hip
0.000 0.027 0.973
C71 Malignant neoplasm of brain
0.000 0.027 0.973
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.030 0.970
C34.1 Upper lobe, bronchus or lung
0.000 0.043 0.957
N41.1 Chronic prostatitis
0.000 0.045 0.955
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.000 0.054 0.946
N42.2 Atrophy of prostate
0.000 0.060 0.940
D47.1 Chronic myeloproliferative disease
0.000 0.063 0.937
C71.9 Brain, unspecified
0.000 0.068 0.932
C67.6 Ureteric orifice
0.000 0.073 0.927
C80 Malignant neoplasm without specification of site
0.000 0.075 0.925
C34.3 Lower lobe, bronchus or lung
0.000 0.076 0.924
C44.2 Skin of ear and external auricular canal
0.000 0.083 0.917
C66 Malignant neoplasm of ureter
0.000 0.088 0.912
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.091 0.909
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.095 0.905
D41.4 Bladder
0.000 0.112 0.888
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.117 0.883
C71.8 Overlapping lesion of brain
0.000 0.117 0.883
C71.2 Temporal lobe
0.000 0.122 0.878
C45 Mesothelioma
0.000 0.123 0.877
C67.2 Lateral wall of bladder
0.000 0.124 0.876
N42.1 Congestion and haemorrhage of prostate
0.000 0.130 0.870
C32 Malignant neoplasm of larynx
0.000 0.144 0.856
N42.0 Calculus of prostate
0.000 0.145 0.855
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.000 0.149 0.851
N41.0 Acute prostatitis
0.000 0.150 0.850
C79.6 Secondary malignant neoplasm of ovary
0.000 0.150 0.850
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.157 0.843
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.162 0.838
C80.9 Malignant neoplasm, unspecified
0.000 0.163 0.837
D39.1 Ovary
0.000 0.165 0.835
C79.2 Secondary malignant neoplasm of skin
0.000 0.167 0.833
C45.0 Mesothelioma of pleura
0.000 0.171 0.829
D47.4 Osteomyelofibrosis
0.000 0.180 0.820
C67.5 Bladder neck
0.000 0.190 0.810
D00-D09 In situ neoplasms
0.000 0.205 0.795
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.212 0.788
D45 Polycythaemia vera
0.000 0.212 0.788
C80.0 Malignant neoplasm, primary site unknown, so stated
0.000 0.225 0.775
C71.4 Occipital lobe
0.000 0.225 0.775
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.239 0.761
D41.2 Ureter
0.000 0.239 0.761
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.239 0.761
C32.9 Larynx, unspecified
0.000 0.244 0.756
C45.9 Mesothelioma, unspecified
0.000 0.245 0.755
C44.0 Skin of lip
0.000 0.246 0.754
C65 Malignant neoplasm of renal pelvis
0.000 0.261 0.739
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.268 0.732
D07.5 Prostate
0.000 0.276 0.724
D39.0 Uterus
0.000 0.276 0.724
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.277 0.723
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
N42.3 Dysplasia of prostate
0.000 0.283 0.717
C67.7 Urachus
0.000 0.283 0.717
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.283 0.717
C31 Malignant neoplasm of accessory sinuses
0.000 0.283 0.717
C34.8 Overlapping lesion of bronchus and lung
0.000 0.284 0.716
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.285 0.715
N41.3 Prostatocystitis
0.000 0.286 0.714
N41.2 Abscess of prostate
0.000 0.286 0.714
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.289 0.711
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.289 0.711
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.289 0.711
C37 Malignant neoplasm of thymus
0.000 0.291 0.709
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.000 0.295 0.705
C70 Malignant neoplasm of meninges
0.000 0.295 0.705
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.000 0.298 0.702
C67.3 Anterior wall of bladder
0.000 0.299 0.701
D41.0 Kidney
0.000 0.300 0.700
C71.7 Brain stem
0.000 0.302 0.698
C71.6 Cerebellum
0.000 0.302 0.698
C71.5 Cerebral ventricle
0.000 0.302 0.698
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.309 0.691
C34.0 Main bronchus
0.000 0.314 0.686
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.315 0.685
C33 Malignant neoplasm of trachea
0.000 0.316 0.684
C67.8 Overlapping lesion of bladder
0.000 0.316 0.683
C34.2 Middle lobe, bronchus or lung
0.000 0.317 0.683
D41.9 Urinary organ, unspecified
0.000 0.322 0.678
D41.7 Other urinary organs
0.000 0.322 0.678
D41.3 Urethra
0.000 0.322 0.678
D41.1 Renal pelvis
0.000 0.322 0.678
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.324 0.676
D40.0 Prostate
0.000 0.327 0.673
D40.1 Testis
0.000 0.327 0.673
D47.2 Monoclonal gammopathy
0.000 0.335 0.665
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.336 0.664
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.343 0.657
C69 Malignant neoplasm of eye and adnexa
0.000 0.346 0.654
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.000 0.348 0.652
C46 Kaposi's sarcoma
0.000 0.348 0.652
D39.9 Female genital organ, unspecified
0.000 0.351 0.649
D39.2 Placenta
0.000 0.351 0.649
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.352 0.648
C71.1 Frontal lobe
0.000 0.352 0.648
D46 Myelodysplastic syndromes
0.000 0.361 0.639
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.362 0.638
C45.7 Mesothelioma of other sites
0.000 0.364 0.636
N46 Male infertility
0.000 0.368 0.632
D06 Carcinoma in situ of cervix uteri
0.000 0.371 0.629
C45.2 Mesothelioma of pericardium
0.000 0.371 0.629
C45.1 Mesothelioma of peritoneum
0.000 0.371 0.629
C71.3 Parietal lobe
0.000 0.373 0.626
C32.0 Glottis
0.000 0.376 0.624
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.382 0.618
C32.8 Overlapping lesion of larynx
0.000 0.386 0.614
C32.3 Laryngeal cartilage
0.000 0.386 0.614
C32.2 Subglottis
0.000 0.386 0.614
C44.4 Skin of scalp and neck
0.000 0.388 0.612
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.390 0.610
D40.9 Male genital organ, unspecified
0.000 0.399 0.600
D40.7 Other male genital organs
0.000 0.399 0.600
C48.2 Peritoneum, unspecified
0.000 0.401 0.599
C32.1 Supraglottis
0.000 0.403 0.597
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.410 0.590
D07.4 Penis
0.000 0.411 0.589
D04 Carcinoma in situ of skin
0.000 0.411 0.589
D07.2 Vagina
0.000 0.417 0.583
N41.8 Other inflammatory diseases of prostate
0.000 0.417 0.582
C71.0 Cerebrum, except lobes and ventricles
0.000 0.418 0.582
D43.0 Brain, supratentorial
0.000 0.426 0.574
C79.8 Secondary malignant neoplasm of other specified sites
0.000 0.428 0.572
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.435 0.565
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.438 0.562
D39.7 Other female genital organs
0.000 0.440 0.560
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.444 0.556
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.445 0.555
N44 Torsion of testis
0.000 0.445 0.555
N45 Orchitis and epididymitis
0.000 0.449 0.551
D09 Carcinoma in situ of other and unspecified sites
0.000 0.452 0.548
D07.6 Other and unspecified male genital organs
0.000 0.454 0.545
D07.3 Other and unspecified female genital organs
0.000 0.454 0.545
D07.0 Endometrium
0.000 0.454 0.545
D04.5 Skin of trunk
0.000 0.459 0.541
C30.0 Nasal cavity
0.000 0.460 0.540
D07.1 Vulva
0.000 0.461 0.539
C79.9 Secondary malignant neoplasm, unspecified site
0.000 0.465 0.535
C69.9 Eye, unspecified
0.000 0.472 0.528
D43.1 Brain, infratentorial
0.000 0.473 0.527
C30.1 Middle ear
0.000 0.475 0.525
D06.9 Cervix, unspecified
0.000 0.479 0.521
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.480 0.519
D43.9 Central nervous system, unspecified
0.000 0.481 0.518
D43.7 Other parts of central nervous system
0.000 0.481 0.518
D43.4 Spinal cord
0.000 0.481 0.518
D43.3 Cranial nerves
0.000 0.481 0.518
C31.9 Accessory sinus, unspecified
0.000 0.486 0.514
C31.8 Overlapping lesion of accessory sinuses
0.000 0.486 0.514
C31.3 Sphenoidal sinus
0.000 0.486 0.514
C31.2 Frontal sinus
0.000 0.486 0.514
C31.1 Ethmoidal sinus
0.000 0.486 0.514
C31.0 Maxillary sinus
0.000 0.486 0.514
C39.9 Ill-defined sites within the respiratory system
0.000 0.486 0.514
C39.8 Overlapping lesion of respiratory and intrathoracic organs
0.000 0.486 0.514
C39.0 Upper respiratory tract, part unspecified
0.000 0.486 0.514
D42.9 Meninges, unspecified
0.000 0.487 0.512
D42.1 Spinal meninges
0.000 0.487 0.512
D42.0 Cerebral meninges
0.000 0.487 0.512
C48.0 Retroperitoneum
0.000 0.490 0.510
C70.9 Meninges, unspecified
0.000 0.494 0.505
C70.1 Spinal meninges
0.000 0.494 0.505
C70.0 Cerebral meninges
0.000 0.494 0.505
C72.9 Central nervous system, unspecified
0.000 0.494 0.505
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.000 0.494 0.505
C72.5 Other and unspecified cranial nerves
0.000 0.494 0.505
C72.4 Acoustic nerve
0.000 0.494 0.505
C72.3 Optic nerve
0.000 0.494 0.505
C72.2 Olfactory nerve
0.000 0.494 0.505
C72.1 Cauda equina
0.000 0.494 0.505
C72.0 Spinal cord
0.000 0.494 0.505
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.000 0.496 0.503
D01.3 Anus and anal canal
0.000 0.497 0.502
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.499 0.500
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.504 0.495
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.504 0.495
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.504 0.495
N49.2 Inflammatory disorders of scrotum
0.000 0.505 0.495
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.000 0.509 0.491
C38.3 Mediastinum, part unspecified
0.000 0.509 0.491
C38.2 Posterior mediastinum
0.000 0.509 0.491
C38.1 Anterior mediastinum
0.000 0.509 0.491
C38.0 Heart
0.000 0.509 0.491
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.514 0.486
D44.6 Carotid body
0.000 0.515 0.485
D48.0 Bone and articular cartilage
0.000 0.518 0.482
D46.7 Other myelodysplastic syndromes
0.000 0.524 0.476
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.000 0.524 0.476
N51.2 Balanitis in diseases classified elsewhere
0.000 0.530 0.470
C69.8 Overlapping lesion of eye and adnexa
0.000 0.531 0.469
C69.6 Orbit
0.000 0.531 0.469
C69.5 Lachrymal gland and duct
0.000 0.531 0.469
C69.4 Ciliary body
0.000 0.531 0.469
C69.2 Retina
0.000 0.531 0.469
C69.1 Cornea
0.000 0.531 0.469
C46.9 Kaposi's sarcoma, unspecified
0.000 0.532 0.467
C46.8 Kaposi's sarcoma of multiple organs
0.000 0.532 0.467
C46.7 Kaposi's sarcoma of other sites
0.000 0.532 0.467
C46.3 Kaposi's sarcoma of lymph nodes
0.000 0.532 0.467
C46.2 Kaposi's sarcoma of palate
0.000 0.532 0.467
C46.1 Kaposi's sarcoma of soft tissue
0.000 0.532 0.467
C46.0 Kaposi's sarcoma of skin
0.000 0.532 0.467
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.000 0.532 0.467
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.000 0.532 0.467
C47.6 Peripheral nerves of trunk, unspecified
0.000 0.532 0.467
C47.5 Peripheral nerves of pelvis
0.000 0.532 0.467
C47.4 Peripheral nerves of abdomen
0.000 0.532 0.467
C47.3 Peripheral nerves of thorax
0.000 0.532 0.467
C47.2 Peripheral nerves of lower limb, including hip
0.000 0.532 0.467
C47.1 Peripheral nerves of upper limb, including shoulder
0.000 0.532 0.467
C47.0 Peripheral nerves of head, face and neck
0.000 0.532 0.467
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.535 0.465
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.535 0.465
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.535 0.465
C69.3 Choroid
0.000 0.536 0.464
D44.4 Craniopharyngeal duct
0.000 0.537 0.463
C67.0 Trigone of bladder
0.001 0.537 0.462
D44.1 Adrenal gland
0.000 0.540 0.460
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.540 0.460
C38.4 Pleura
0.000 0.541 0.459
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.000 0.542 0.458
D46.5 Refractory anaemia with multi-lineage dysplasia
0.000 0.542 0.458
D46.3 Refractory anaemia with excess of blasts with transformation
0.000 0.542 0.458
D46.1 Refractory anaemia with sideroblasts
0.000 0.542 0.458
D46.0 Refractory anaemia without sideroblasts, so stated
0.000 0.542 0.458
D44.9 Endocrine gland, unspecified
0.000 0.543 0.457
D44.7 Aortic body and other paraganglia
0.000 0.543 0.457
D44.5 Pineal gland
0.000 0.543 0.457
D44.2 Parathyroid gland
0.000 0.543 0.457
D44.8 Pluriglandular involvement
0.000 0.545 0.455
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.000 0.546 0.454
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.548 0.452
D06.7 Other parts of cervix
0.000 0.549 0.451
D06.1 Exocervix
0.000 0.549 0.451
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.000 0.552 0.448
D46.2 Refractory anaemia with excess of blasts
0.000 0.555 0.445
D02.0 Larynx
0.000 0.556 0.443
C68.8 Overlapping lesion of urinary organs
0.000 0.557 0.443
C68.1 Paraurethral glands
0.000 0.557 0.443
D43.2 Brain, unspecified
0.000 0.559 0.441
D01.2 Rectum
0.000 0.560 0.440
D01.9 Digestive organ, unspecified
0.000 0.563 0.437
D01.7 Other specified digestive organs
0.000 0.563 0.437
D01.5 Liver, gallbladder and bile ducts
0.000 0.563 0.437
D01.4 Other and unspecified parts of intestine
0.000 0.563 0.437
D01.1 Rectosigmoid junction
0.000 0.563 0.437
D04.9 Skin, unspecified
0.000 0.563 0.437
D44.3 Pituitary gland
0.000 0.564 0.436
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.000 0.566 0.434
D00.1 Oesophagus
0.000 0.567 0.433
D06.0 Endocervix
0.000 0.567 0.433
D04.6 Skin of upper limb, including shoulder
0.000 0.569 0.431
C77.9 Lymph node, unspecified
0.000 0.569 0.431
D48.2 Peripheral nerves and autonomic nervous system
0.000 0.571 0.429
C50-C50 Malignant neoplasm of breast
0.000 0.576 0.424
D02.4 Respiratory system, unspecified
0.000 0.576 0.423
D02.3 Other parts of respiratory system
0.000 0.576 0.423
D02.2 Bronchus and lung
0.000 0.576 0.423
D02.1 Trachea
0.000 0.576 0.423
D04.8 Skin of other sites
0.000 0.578 0.422
D04.0 Skin of lip
0.000 0.578 0.422
D04.2 Skin of ear and external auricular canal
0.000 0.580 0.420
D04.1 Skin of eyelid, including canthus
0.000 0.581 0.419
C68.9 Urinary organ, unspecified
0.000 0.588 0.412
C77.0 Lymph nodes of head, face and neck
0.000 0.588 0.412
C48.1 Specified parts of peritoneum
0.000 0.592 0.407
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.596 0.404
D00.2 Stomach
0.000 0.597 0.403
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.600 0.400
D48.3 Retroperitoneum
0.000 0.602 0.398
D04.7 Skin of lower limb, including hip
0.000 0.604 0.396
C74 Malignant neoplasm of adrenal gland
0.000 0.606 0.394
D09.9 Carcinoma in situ, unspecified
0.000 0.607 0.393
D09.7 Carcinoma in situ of other specified sites
0.000 0.607 0.393
D09.3 Thyroid and other endocrine glands
0.000 0.607 0.393
D09.2 Eye
0.000 0.607 0.393
D01.0 Colon
0.000 0.607 0.392
D09.1 Other and unspecified urinary organs
0.000 0.608 0.392
C67.1 Dome of bladder
0.001 0.608 0.391
D04.4 Skin of scalp and neck
0.000 0.610 0.390
C68.0 Urethra
0.000 0.615 0.385
C92 Myeloid leukaemia
0.000 0.620 0.380
C76.3 Pelvis
0.000 0.626 0.374
C76.8 Overlapping lesion of other and ill-defined sites
0.000 0.627 0.372
C76.7 Other ill-defined sites
0.000 0.627 0.372
C76.5 Lower limb
0.000 0.627 0.372
C76.4 Upper limb
0.000 0.627 0.372
D48.4 Peritoneum
0.000 0.629 0.371
D09.0 Bladder
0.000 0.629 0.371
C41.0 Bones of skull and face
0.000 0.634 0.366
C76.2 Abdomen
0.000 0.636 0.364
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.637 0.363
D44.0 Thyroid gland
0.000 0.642 0.357
D00.0 Lip, oral cavity and pharynx
0.000 0.645 0.355
N49.8 Inflammatory disorders of other specified male genital organs
0.001 0.653 0.347
D48.6 Breast
0.000 0.653 0.347
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)
0.000 0.658 0.341
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)
0.000 0.658 0.341
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)
0.000 0.658 0.341
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)
0.000 0.658 0.341
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)
0.000 0.658 0.341
C92.1 Chronic myeloid leukaemia
0.000 0.663 0.337
C92.0 Acute myeloid leukaemia
0.000 0.666 0.334
C90.2 Plasmacytoma, extramedullary
0.000 0.666 0.334
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.671 0.329
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.673 0.327
C40.9 Bone and articular cartilage of limb, unspecified
0.000 0.674 0.326
C40.8 Overlapping lesion of bone and articular cartilage of limbs
0.000 0.674 0.326
C40.3 Short bones of lower limb
0.000 0.674 0.326
C40.1 Short bones of upper limb
0.000 0.674 0.326
C40.0 Scapula and long bones of upper limb
0.000 0.674 0.326
D38.6 Respiratory organ, unspecified
0.000 0.676 0.324
D38.4 Thymus
0.000 0.676 0.324
D38.3 Mediastinum
0.000 0.676 0.324
D38.2 Pleura
0.000 0.676 0.324
D46.4 Refractory anaemia, unspecified
0.001 0.677 0.323
C41.8 Overlapping lesion of bone and articular cartilage
0.000 0.678 0.321
C41.3 Ribs, sternum and clavicle
0.000 0.678 0.321
C41.2 Vertebral column
0.000 0.678 0.321
C69.0 Conjunctiva
0.001 0.681 0.319
C77.1 Intrathoracic lymph nodes
0.000 0.681 0.319
C74.9 Adrenal gland, unspecified
0.000 0.682 0.318
C41.9 Bone and articular cartilage, unspecified
0.000 0.685 0.314
C76.1 Thorax
0.001 0.691 0.309
D38.0 Larynx
0.000 0.692 0.308
C77.5 Intrapelvic lymph nodes
0.000 0.694 0.306
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.695 0.305
C40.2 Long bones of lower limb
0.000 0.696 0.304
D48.5 Skin
0.000 0.697 0.302
D05 Carcinoma in situ of breast
0.000 0.698 0.302
D48.1 Connective and other soft tissue
0.000 0.702 0.298
C76.0 Head, face and neck
0.001 0.707 0.292
D48.7 Other specified sites
0.000 0.707 0.293
C93 Monocytic leukaemia
0.000 0.708 0.292
C41.4 Pelvic bones, sacrum and coccyx
0.000 0.708 0.291
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.710 0.290
C94 Other leukaemias of specified cell type
0.000 0.710 0.290
C86 Other specified types of T/NK-cell lymphoma
0.000 0.710 0.290
C77.8 Lymph nodes of multiple regions
0.000 0.713 0.287
C88 Malignant immunoproliferative diseases
0.000 0.717 0.283
C74.1 Medulla of adrenal gland
0.000 0.717 0.283
C74.0 Cortex of adrenal gland
0.000 0.717 0.283
C92.4 Acute promyelocytic leukaemia
0.000 0.720 0.280
C84.4 Peripheral T-cell lymphoma
0.000 0.725 0.275
C12 Malignant neoplasm of pyriform sinus
0.000 0.726 0.273
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.728 0.272
C92.7 Other myeloid leukaemia
0.000 0.728 0.272
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.728 0.272
C92.5 Acute myelomonocytic leukaemia
0.000 0.728 0.272
C92.3 Myeloid sarcoma
0.000 0.728 0.272
C92.2 Subacute myeloid leukaemia
0.000 0.728 0.272
C41.1 Mandible
0.000 0.734 0.265
C01 Malignant neoplasm of base of tongue
0.000 0.735 0.265
C92.9 Myeloid leukaemia, unspecified
0.000 0.737 0.263
C49 Malignant neoplasm of other connective and soft tissue
0.001 0.738 0.261
C90.1 Plasma cell leukaemia
0.000 0.738 0.261
C90.3 Solitary plasmacytoma
0.000 0.740 0.260
C90.0 Multiple myeloma
0.000 0.742 0.258
D38.5 Other respiratory organs
0.001 0.749 0.250
C84.0 Mycosis fungoides
0.000 0.755 0.245
C95 Leukaemia of unspecified cell type
0.000 0.762 0.238
C97 Malignant neoplasms of independent (primary) multiple sites
0.001 0.763 0.236
C75.8 Pluriglandular involvement, unspecified
0.000 0.764 0.236
C75.5 Aortic body and other paraganglia
0.000 0.764 0.236
C75.4 Carotid body
0.000 0.764 0.236
C75.3 Pineal gland
0.000 0.764 0.236
C75.2 Craniopharyngeal duct
0.000 0.764 0.236
C75.1 Pituitary gland
0.000 0.764 0.236
C75.0 Parathyroid gland
0.000 0.764 0.236
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.766 0.234
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.766 0.234
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.766 0.234
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.766 0.234
C84.3 Lymphoepithelioid lymphoma
0.000 0.766 0.234
C84.2 T-zone lymphoma
0.000 0.766 0.234
C84.1 Sezary's diease
0.000 0.766 0.234
D38.1 Trachea, bronchus and lung
0.001 0.768 0.232
D05.7 Other carcinoma in situ of breast
0.000 0.776 0.224
D05.1 Intraductal carcinoma in situ
0.000 0.778 0.222
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.779 0.221
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.779 0.221
C81 Hodgkin's disease
0.000 0.780 0.220
C84.5 Other and unspecified T-cell lymphomas
0.000 0.785 0.215
C60-C63 Malignant neoplasms of male genital organs
0.015 0.785 0.199
C93.1 Chronic monocytic leukaemia
0.000 0.789 0.211
C11 Malignant neoplasm of nasopharynx
0.000 0.789 0.210
C93.9 Monocytic leukaemia, unspecified
0.000 0.791 0.209
C93.7 Other monocytic leukaemia
0.000 0.791 0.209
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.791 0.209
C93.2 Subacute monocytic leukaemia
0.000 0.791 0.209
C93.0 Acute monocytic leukaemia
0.000 0.791 0.209
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.792 0.208
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.792 0.208
C86.4 Blastic NK-cell lymphoma
0.000 0.792 0.208
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.792 0.208
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.792 0.208
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.792 0.208
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.792 0.208
C94.7 Other specified leukaemias
0.000 0.792 0.208
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.792 0.208
C94.5 Acute myelofibrosis
0.000 0.792 0.208
C94.4 Acute panmyelosis
0.000 0.792 0.208
C94.3 Mast cell leukaemia
0.000 0.792 0.208
C94.2 Acute megakaryoblastic leukaemia
0.000 0.792 0.208
C94.1 Chronic erythraemia
0.000 0.792 0.208
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.792 0.208
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.792 0.208
C96.8 Histiocytic sarcoma
0.000 0.792 0.208
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.792 0.208
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.792 0.208
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.792 0.208
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.792 0.208
C96.3 True histiocytic lymphoma
0.000 0.792 0.208
C96.2 Malignant mast cell tumour
0.000 0.792 0.208
C96.1 Malignant histiocytosis
0.000 0.792 0.208
C96.0 Letterer-Siwe disease
0.000 0.792 0.208
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.793 0.207
C75.9 Endocrine gland, unspecified
0.001 0.794 0.206
N43 Hydrocele and spermatocele
0.001 0.795 0.204
C09 Malignant neoplasm of tonsil
0.000 0.796 0.203
C10 Malignant neoplasm of oropharynx
0.000 0.797 0.203
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.797 0.203
C88.7 Other malignant immunoproliferative diseases
0.000 0.797 0.203
C88.3 Immunoproliferative small intestinal disease
0.000 0.797 0.203
C88.2 Gamma heavy chain disease
0.000 0.797 0.203
C88.1 Alpha heavy chain disease
0.000 0.797 0.203
C49.5 Connective and soft tissue of pelvis
0.001 0.798 0.202
C13 Malignant neoplasm of hypopharynx
0.000 0.799 0.200
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.800 0.200
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.800 0.199
C49.0 Connective and soft tissue of head, face and neck
0.001 0.803 0.197
C04 Malignant neoplasm of floor of mouth
0.000 0.806 0.193
C00 Malignant neoplasm of lip
0.001 0.807 0.193
C03 Malignant neoplasm of gum
0.001 0.807 0.192
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.810 0.189
C49.8 Overlapping lesion of connective and soft tissue
0.001 0.812 0.187
C49.6 Connective and soft tissue of trunk, unspecified
0.001 0.812 0.187
C51-C58 Malignant neoplasms of female genital organs
0.000 0.818 0.182
C14.0 Pharynx, unspecified
0.000 0.820 0.180
C08 Malignant neoplasm of other and unspecified major salivary glands
0.001 0.823 0.176
D04.3 Skin of other and unspecified parts of face
0.001 0.829 0.170
C95.7 Other leukaemia of unspecified cell type
0.000 0.829 0.171
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.829 0.171
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.829 0.171
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.831 0.169
C02.1 Border of tongue
0.000 0.833 0.167
D05.0 Lobular carcinoma in situ
0.000 0.833 0.167
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.836 0.164
C49.2 Connective and soft tissue of lower limb, including hip
0.001 0.836 0.163
N50 Other disorders of male genital organs
0.000 0.837 0.163
C49.4 Connective and soft tissue of abdomen
0.001 0.839 0.160
C49.9 Connective and soft tissue, unspecified
0.001 0.839 0.160
C81.0 Lymphocytic predominance
0.000 0.840 0.160
C14.2 Waldeyer's ring
0.000 0.841 0.159
C81.7 Other Hodgkin's disease
0.000 0.842 0.158
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.842 0.158
C81.3 Lymphocytic depletion
0.000 0.842 0.158
C63 Malignant neoplasm of other and unspecified male genital organs
0.011 0.846 0.143
C95.9 Leukaemia, unspecified
0.000 0.847 0.153
C11.8 Overlapping lesion of nasopharynx
0.000 0.849 0.151
C11.3 Anterior wall of nasopharynx
0.000 0.849 0.151
C11.2 Lateral wall of nasopharynx
0.000 0.849 0.151
C11.1 Posterior wall of nasopharynx
0.000 0.849 0.151
C11.0 Superior wall of nasopharynx
0.000 0.849 0.151
C02.8 Overlapping lesion of tongue
0.000 0.851 0.148
C02.3 Anterior two-thirds of tongue, part unspecified
0.000 0.851 0.148
C02.0 Dorsal surface of tongue
0.000 0.851 0.148
N32.8 Other specified disorders of bladder
0.000 0.852 0.148
C07 Malignant neoplasm of parotid gland
0.001 0.852 0.147
N43.0 Encysted hydrocele
0.001 0.853 0.147
C02.2 Ventral surface of tongue
0.000 0.853 0.146
C09.8 Overlapping lesion of tonsil
0.000 0.854 0.146
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.854 0.146

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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