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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3731189
log Bayes Factor = 12.1962
Chromosome 3   position 14,186,238  (GRCh37) Explore rs3731189 on Ensembl!
Variant rs3731189 is part of Cluster X0089

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.990 0.010 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.986 0.014 0.000
Z36 Antenatal screening
0.980 0.020 0.000
O36 Maternal care for other known or suspected foetal problems
0.977 0.023 0.000
F30-F39 Mood [affective] disorders
0.972 0.028 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.968 0.032 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.967 0.033 0.000
Chapter XI Diseases of the digestive system
0.964 0.036 0.000
Z37 Outcome of delivery
0.956 0.044 0.000
K70-K77 Diseases of liver
0.955 0.045 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.955 0.045 0.000
F32 Depressive episode
0.945 0.055 0.000
O70 Perineal laceration during delivery
0.944 0.056 0.000
S00-S09 Injuries to the head
0.944 0.056 0.000
Z36.8 Other antenatal screening
0.943 0.057 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.943 0.057 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.939 0.061 0.000
K22 Other diseases of oesophagus
0.937 0.063 0.000
Z37.0 Single live birth
0.930 0.070 0.000
Chapter VI Diseases of the nervous system
0.928 0.072 0.000
O48 Prolonged pregnancy
0.924 0.076 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.923 0.077 0.000
F32.9 Depressive episode, unspecified
0.921 0.079 0.000
Chapter I Certain infectious and parasitic diseases
0.917 0.083 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.915 0.085 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.912 0.088 0.000
K70 Alcoholic liver disease
0.910 0.090 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.909 0.091 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.907 0.093 0.000
O42 Premature rupture of membranes
0.904 0.096 0.000
O36.9 Maternal care for foetal problem, unspecified
0.904 0.096 0.000
Z60 Problems related to social environment
0.902 0.098 0.000
O63 Long labour
0.902 0.098 0.000
O72 Postpartum haemorrhage
0.901 0.099 0.000
Chapter XIV Diseases of the genitourinary system
0.901 0.099 0.000
S80-S89 Injuries to the knee and lower leg
0.888 0.112 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.888 0.112 0.000
O36.8 Maternal care for other specified foetal problems
0.885 0.115 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.883 0.117 0.000
G90-G99 Other disorders of the nervous system
0.883 0.117 0.000
S00 Superficial injury of head
0.882 0.118 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.880 0.120 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.880 0.120 0.000
K22.1 Ulcer of oesophagus
0.879 0.121 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.878 0.122 0.000
Z63 Other problems related to primary support group, including family circumstances
0.875 0.125 0.000
K31 Other diseases of stomach and duodenum
0.873 0.127 0.000
K22.7 Barrett's oesophagus
0.869 0.131 0.000
N60-N64 Disorders of breast
0.867 0.133 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.867 0.133 0.000
G30-G32 Other degenerative diseases of the nervous system
0.864 0.136 0.000
O20 Haemorrhage in early pregnancy
0.863 0.137 0.000
Chapter VII Diseases of the eye and adnexa
0.859 0.141 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.858 0.142 0.000
K76 Other diseases of liver
0.857 0.143 0.000
Z60.2 Living alone
0.855 0.145 0.000
K22.9 Disease of oesophagus, unspecified
0.853 0.147 0.000
N17-N19 Renal failure
0.851 0.149 0.000
O70.1 Second degree perineal laceration during delivery
0.851 0.149 0.000
Z36.9 Antenatal screening, unspecified
0.850 0.150 0.000
Z72 Problems related to lifestyle
0.849 0.151 0.000
K70.9 Alcoholic liver disease, unspecified
0.845 0.155 0.000
B35-B49 Mycoses
0.844 0.156 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.844 0.156 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.841 0.159 0.000
O47 False labour
0.841 0.159 0.000
O69.8 Labour and delivery complicated by other cord complications
0.840 0.160 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.838 0.162 0.000
O40 Polyhydramnios
0.834 0.166 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.829 0.171 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.828 0.172 0.000
S02 Fracture of skull and facial bones
0.827 0.173 0.000
Z72.1 Alcohol use
0.824 0.176 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.819 0.181 0.000
O42.9 Premature rupture of membranes, unspecified
0.817 0.183 0.000
H53-H54 Visual disturbances and blindness
0.815 0.185 0.000
O16 Unspecified maternal hypertension
0.814 0.186 0.000
L85 Other epidermal thickening
0.811 0.188 0.000
O70.0 First degree perineal laceration during delivery
0.810 0.190 0.000
Z35 Supervision of high-risk pregnancy
0.809 0.191 0.000
O62 Abnormalities of forces of labour
0.805 0.194 0.000
O66 Other obstructed labour
0.804 0.196 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.803 0.197 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.802 0.198 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.801 0.199 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.798 0.202 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.797 0.203 0.000
K74 Fibrosis and cirrhosis of liver
0.796 0.204 0.000
F31 Bipolar affective disorder
0.796 0.204 0.000
O46.9 Antepartum haemorrhage, unspecified
0.795 0.205 0.000
N62 Hypertrophy of breast
0.794 0.205 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.794 0.206 0.000
L91 Hypertrophic disorders of skin
0.794 0.206 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.793 0.207 0.000
N18 Chronic renal failure
0.790 0.210 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.790 0.210 0.000
O61 Failed induction of labour
0.789 0.210 0.000
O80-O84 Delivery
0.789 0.211 0.000
S80 Superficial injury of lower leg
0.788 0.212 0.000
Z31 Procreative management
0.786 0.214 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.786 0.214 0.000
K12 Stomatitis and related lesions
0.783 0.217 0.000
H53 Visual disturbances
0.783 0.217 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.783 0.217 0.000
O63.1 Prolonged second stage (of labour)
0.783 0.217 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.783 0.217 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.782 0.218 0.000
B37 Candidiasis
0.778 0.222 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.777 0.223 0.000
T43.2 Other and unspecified antidepressants
0.776 0.224 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.774 0.226 0.000
E10-E14 Diabetes mellitus
0.772 0.228 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.770 0.230 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.767 0.233 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.765 0.235 0.000
B15-B19 Viral hepatitis
0.764 0.236 0.000
N63 Unspecified lump in breast
0.763 0.237 0.000
F33 Recurrent depressive disorder
0.762 0.237 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.762 0.238 0.000
F10.2 Dependence syndrome
0.761 0.239 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.761 0.239 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.760 0.240 0.000
O73 Retained placenta and membranes, without haemorrhage
0.758 0.242 0.000
S00.1 Contusion of eyelid and periocular area
0.756 0.244 0.000
O24 Diabetes mellitus in pregnancy
0.755 0.244 0.000
N00-N08 Glomerular diseases
0.755 0.245 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.754 0.246 0.000
Z34 Supervision of normal pregnancy
0.754 0.246 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.753 0.247 0.000
K76.9 Liver disease, unspecified
0.752 0.248 0.000
G96 Other disorders of central nervous system
0.750 0.250 0.000
Q80-Q89 Other congenital malformations
0.749 0.251 0.000
G93 Other disorders of brain
0.749 0.251 0.000
Z63.0 Problems in relationship with spouse or partner
0.748 0.252 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.747 0.253 0.000
S81 Open wound of lower leg
0.747 0.253 0.000
O43 Placental disorders
0.743 0.257 0.000
H53.1 Subjective visual disturbances
0.742 0.258 0.000
L85.9 Epidermal thickening, unspecified
0.741 0.259 0.000
O63.0 Prolonged first stage (of labour)
0.741 0.259 0.000
Z75 Problems related to medical facilities and other health care
0.741 0.259 0.000
O30 Multiple gestation
0.739 0.261 0.000
E00-E07 Disorders of thyroid gland
0.739 0.261 0.000
L94 Other localised connective tissue disorders
0.738 0.262 0.000
K75 Other inflammatory liver diseases
0.738 0.262 0.000
A30-A49 Other bacterial diseases
0.737 0.263 0.000
O00-O08 Pregnancy with abortive outcome
0.737 0.263 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
M50-M54 Other dorsopathies
0.735 0.265 0.000
K22.2 Oesophageal obstruction
0.734 0.266 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.734 0.266 0.000
K72 Hepatic failure, not elsewhere classified
0.733 0.267 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.733 0.267 0.000
O26.8 Other specified pregnancy-related conditions
0.732 0.268 0.000
K76.6 Portal hypertension
0.732 0.268 0.000
K14 Diseases of tongue
0.732 0.268 0.000
M80-M85 Disorders of bone density and structure
0.731 0.269 0.000
K31.5 Obstruction of duodenum
0.731 0.269 0.000
T40.2 Other opioids
0.730 0.270 0.000
S90-S99 Injuries to the ankle and foot
0.729 0.271 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.729 0.271 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.729 0.271 0.000
K70.1 Alcoholic hepatitis
0.728 0.272 0.000
F80-F89 Disorders of psychological development
0.727 0.273 0.000
K22.5 Diverticulum of oesophagus, acquired
0.727 0.273 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.727 0.273 0.000
A80-A89 Viral infections of the central nervous system
0.726 0.274 0.000
F32.0 Mild depressive episode
0.725 0.274 0.000
B37.0 Candidal stomatitis
0.725 0.275 0.000
Chapter X Diseases of the respiratory system
0.725 0.275 0.000
O72.0 Third-stage haemorrhage
0.724 0.275 0.000
O21 Excessive vomiting in pregnancy
0.724 0.276 0.000
Z39 Postpartum care and examination
0.723 0.276 0.000
K07 Dentofacial anomalies [including malocclusion]
0.723 0.277 0.000
Z57 Occupational exposure to risk-factors
0.723 0.277 0.000
N10-N16 Renal tubulo-interstitial diseases
0.722 0.278 0.000
K31.8 Other specified diseases of stomach and duodenum
0.721 0.279 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.720 0.280 0.000
S00.9 Superficial injury of head, part unspecified
0.719 0.281 0.000
Chapter XXII Codes for special purposes
0.719 0.281 0.000
O70.2 Third degree perineal laceration during delivery
0.718 0.282 0.000
O72.1 Other immediate postpartum haemorrhage
0.718 0.282 0.000
T39.1 4-Aminophenol derivatives
0.718 0.282 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O74 Complications of anaesthesia during labour and delivery
0.717 0.283 0.000
O71 Other obstetric trauma
0.717 0.283 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.717 0.283 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.717 0.283 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.717 0.283 0.000
O60 Preterm delivery
0.717 0.283 0.000
O45 Premature separation of placenta [abruptio placentae]
0.717 0.283 0.000
O44 Placenta praevia
0.717 0.283 0.000
O41 Other disorders of amniotic fluid and membranes
0.717 0.283 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.717 0.283 0.000
O33 Maternal care for known or suspected disproportion
0.717 0.283 0.000
O31 Complications specific to multiple gestation
0.717 0.283 0.000
S00.3 Superficial injury of nose
0.715 0.285 0.000
K10 Other diseases of jaws
0.714 0.286 0.000
M54 Dorsalgia
0.713 0.287 0.000
Z38 Liveborn infants according to place of birth
0.713 0.287 0.000
Z32 Pregnancy examination and test
0.713 0.287 0.000
T33-T35 Frostbite
0.712 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.287 0.000
S10-S19 Injuries to the neck
0.712 0.287 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.712 0.288 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.290 0.000
F70-F79 Mental retardation
0.710 0.290 0.000
F60-F69 Disorders of adult personality and behaviour
0.710 0.290 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.707 0.293 0.000
G30 Alzheimer's disease
0.705 0.295 0.000
Z63.8 Other specified problems related to primary support group
0.704 0.296 0.000
S02.4 Fracture of malar and maxillary bones
0.704 0.296 0.000
Z76 Persons encountering health services in other circumstances
0.704 0.296 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.703 0.296 0.000
Z36.5 Antenatal screening for isoimmunisation
0.703 0.297 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.703 0.297 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.703 0.297 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.703 0.297 0.000
K70.0 Alcoholic fatty liver
0.703 0.297 0.000
O36.6 Maternal care for excessive foetal growth
0.702 0.298 0.000
Z74 Problems related to care-provider dependency
0.701 0.299 0.000
H40-H42 Glaucoma
0.701 0.299 0.000
K29 Gastritis and duodenitis
0.701 0.299 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.700 0.300 0.000
O36.4 Maternal care for intra-uterine death
0.700 0.300 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.700 0.300 0.000
O36.2 Maternal care for hydrops foetalis
0.700 0.300 0.000
O36.1 Maternal care for other isoimmunisation
0.700 0.300 0.000
N18.9 Chronic renal failure, unspecified
0.700 0.300 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.699 0.301 0.000
N60 Benign mammary dysplasia
0.698 0.302 0.000
K12.1 Other forms of stomatitis
0.698 0.302 0.000
Z73 Problems related to life-management difficulty
0.698 0.302 0.000
E14 Unspecified diabetes mellitus
0.698 0.302 0.000
O36.5 Maternal care for poor foetal growth
0.697 0.303 0.000
S00.0 Superficial injury of scalp
0.697 0.303 0.000
F38 Other mood [affective] disorders
0.696 0.303 0.000
F34 Persistent mood [affective] disorders
0.696 0.303 0.000
F30 Manic episode
0.696 0.303 0.000
F39 Unspecified mood [affective] disorder
0.696 0.303 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.696 0.304 0.000
K65-K67 Diseases of peritoneum
0.696 0.304 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.695 0.305 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.694 0.306 0.000
Z65 Problems related to other psychosocial circumstances
0.694 0.306 0.000
Z64 Problems related to certain psychosocial circumstances
0.694 0.306 0.000
Z62 Other problems related to upbringing
0.694 0.306 0.000
Z61 Problems related to negative life events in childhood
0.694 0.306 0.000
Z59 Problems related to housing and economic circumstances
0.694 0.306 0.000
Z58 Problems related to physical environment
0.694 0.306 0.000
Z56 Problems related to employment and unemployment
0.694 0.306 0.000
Z55 Problems related to education and literacy
0.694 0.306 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.693 0.306 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.306 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.693 0.306 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.693 0.306 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.693 0.306 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.693 0.306 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.693 0.306 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.693 0.306 0.000
T36 Poisoning by systemic antibiotics
0.693 0.306 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.693 0.307 0.000
E05.9 Thyrotoxicosis, unspecified
0.693 0.307 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.693 0.307 0.000
B25-B34 Other viral diseases
0.692 0.308 0.000
G90 Disorders of autonomic nervous system
0.692 0.308 0.000
K22.0 Achalasia of cardia
0.690 0.310 0.000
S09 Other and unspecified injuries of head
0.689 0.311 0.000
G95 Other diseases of spinal cord
0.689 0.311 0.000
N17 Acute renal failure
0.687 0.313 0.000
Z37.9 Outcome of delivery unspecified
0.686 0.314 0.000
Z37.7 Other multiple births, all stillborn
0.686 0.314 0.000
Z37.6 Other multiple births, some liveborn
0.686 0.314 0.000
Z37.5 Other multiple births, all liveborn
0.686 0.314 0.000
Z37.4 Twins, both stillborn
0.686 0.314 0.000
Z37.3 Twins, one liveborn and one stillborn
0.686 0.314 0.000
Z37.1 Single stillbirth
0.686 0.314 0.000
K77 Liver disorders in diseases classified elsewhere
0.685 0.315 0.000
K73 Chronic hepatitis, not elsewhere classified
0.685 0.315 0.000
K71 Toxic liver disease
0.685 0.315 0.000
Z37.2 Twins, both liveborn
0.685 0.315 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.685 0.315 0.000
O29 Complications of anaesthesia during pregnancy
0.684 0.315 0.000
O28 Abnormal findings on antenatal screening of mother
0.684 0.315 0.000
O23 Infections of genito-urinary tract in pregnancy
0.684 0.315 0.000
O22 Venous complications in pregnancy
0.684 0.315 0.000
O25 Malnutrition in pregnancy
0.684 0.315 0.000
A00-A09 Intestinal infectious diseases
0.684 0.316 0.000
Z63.4 Disappearance and death of family member
0.683 0.317 0.000
N64 Other disorders of breast
0.682 0.318 0.000
K70.3 Alcoholic cirrhosis of liver
0.681 0.319 0.000
O47.9 False labour, unspecified
0.681 0.319 0.000
S80.9 Superficial injury of lower leg, unspecified
0.679 0.321 0.000
F99-F99 Unspecified mental disorder
0.678 0.321 0.000
L82 Seborrhoeic keratosis
0.678 0.322 0.000
F32.8 Other depressive episodes
0.677 0.323 0.000
O70.9 Perineal laceration during delivery, unspecified
0.677 0.323 0.000
O70.3 Fourth degree perineal laceration during delivery
0.677 0.323 0.000
S08 Traumatic amputation of part of head
0.677 0.323 0.000
S07 Crushing injury of head
0.677 0.323 0.000
S05 Injury of eye and orbit
0.677 0.323 0.000
S04 Injury of cranial nerves
0.677 0.323 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.677 0.323 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.676 0.324 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.676 0.324 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.676 0.324 0.000
O69.3 Labour and delivery complicated by short cord
0.676 0.324 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.676 0.324 0.000
K04 Diseases of pulp and periapical tissues
0.674 0.326 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.674 0.326 0.000
K28 Gastrojejunal ulcer
0.673 0.327 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.673 0.327 0.000
K22.3 Perforation of oesophagus
0.671 0.328 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.671 0.329 0.000
L91.0 Keloid scar
0.671 0.329 0.000
E11 Non-insulin-dependent diabetes mellitus
0.670 0.330 0.000
S02.7 Multiple fractures involving skull and facial bones
0.670 0.330 0.000
G20-G26 Extrapyramidal and movement disorders
0.668 0.332 0.000
K22.8 Other specified diseases of oesophagus
0.664 0.336 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.664 0.336 0.000
Q60-Q64 Congenital malformations of the urinary system
0.663 0.337 0.000
K22.4 Dyskinesia of oesophagus
0.663 0.337 0.000
J95-J99 Other diseases of the respiratory system
0.663 0.337 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.662 0.338 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.662 0.338 0.000
S70-S79 Injuries to the hip and thigh
0.662 0.338 0.000
O63.9 Long labour, unspecified
0.660 0.339 0.000
M54.5 Low back pain
0.660 0.340 0.000
N18.0 End-stage renal disease
0.660 0.340 0.000
B99-B99 Other infectious diseases
0.658 0.342 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.658 0.342 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.658 0.342 0.000
B65-B83 Helminthiases
0.658 0.342 0.000
B50-B64 Protozoal diseases
0.658 0.342 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.658 0.342 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.658 0.342 0.000
A75-A79 Rickettsioses
0.658 0.342 0.000
A70-A74 Other diseases caused by chlamydiae
0.658 0.342 0.000
A65-A69 Other spirochaetal diseases
0.658 0.342 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.658 0.342 0.000
A20-A28 Certain zoonotic bacterial diseases
0.658 0.342 0.000
A15-A19 Tuberculosis
0.658 0.342 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.655 0.345 0.000
S60-S69 Injuries to the wrist and hand
0.655 0.345 0.000
S82 Fracture of lower leg, including ankle
0.655 0.345 0.000
L84 Corns and callosities
0.654 0.346 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.654 0.346 0.000
L10-L14 Bullous disorders
0.654 0.346 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.653 0.346 0.000
K31.7 Polyp of stomach and duodenum
0.653 0.346 0.000
M84 Disorders of continuity of bone
0.653 0.347 0.000
K74.6 Other and unspecified cirrhosis of liver
0.653 0.347 0.000
K70.4 Alcoholic hepatic failure
0.652 0.348 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.652 0.348 0.000
O15 Eclampsia
0.652 0.348 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.652 0.348 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.652 0.348 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.652 0.348 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.652 0.348 0.000
H10-H13 Disorders of conjunctiva
0.651 0.349 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.651 0.349 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.651 0.349 0.000
L93 Lupus erythematosus
0.651 0.349 0.000
L87 Transepidermal elimination disorders
0.651 0.349 0.000
L88 Pyoderma gangrenosum
0.651 0.349 0.000
L86 Keratoderma in diseases classified elsewhere
0.651 0.349 0.000
L83 Acanthosis nigricans
0.651 0.349 0.000
L80 Vitiligo
0.651 0.349 0.000
K11 Diseases of salivary glands
0.650 0.350 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.650 0.350 0.000
Z35.8 Supervision of other high-risk pregnancies
0.650 0.350 0.000
F31.9 Bipolar affective disorder, unspecified
0.649 0.351 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.648 0.351 0.000
N19 Unspecified renal failure
0.648 0.352 0.000
Z60.9 Problem related to social environment, unspecified
0.647 0.353 0.000
Z60.8 Other problems related to social environment
0.647 0.353 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.647 0.353 0.000
Z60.4 Social exclusion and rejection
0.647 0.353 0.000
Z60.3 Acculturation difficulty
0.647 0.353 0.000
Z60.1 Atypical parenting situation
0.647 0.353 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.647 0.353 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.647 0.353 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.647 0.353 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.646 0.354 0.000
O72.3 Postpartum coagulation defects
0.646 0.354 0.000
L81 Other disorders of pigmentation
0.646 0.354 0.000
L91.8 Other hypertrophic disorders of skin
0.646 0.354 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.645 0.355 0.000
K00 Disorders of tooth development and eruption
0.644 0.356 0.000
Q00-Q07 Congenital malformations of the nervous system
0.644 0.356 0.000
H53.0 Amblyopia ex anopsia
0.643 0.357 0.000
G31.8 Other specified degenerative diseases of nervous system
0.642 0.358 0.000
E40-E46 Malnutrition
0.642 0.358 0.000
B44 Aspergillosis
0.642 0.358 0.000
S80.8 Other superficial injuries of lower leg
0.641 0.359 0.000
O61.0 Failed medical induction of labour
0.639 0.361 0.000
Z31.4 Procreative investigation and testing
0.638 0.362 0.000
H55-H59 Other disorders of eye and adnexa
0.638 0.362 0.000
M54.9 Dorsalgia, unspecified
0.637 0.363 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.637 0.363 0.000
O62.3 Precipitate labour
0.637 0.363 0.000
S89 Other and unspecified injuries of lower leg
0.637 0.363 0.000
S88 Traumatic amputation of lower leg
0.637 0.363 0.000
S87 Crushing injury of lower leg
0.637 0.363 0.000
S86 Injury of muscle and tendon at lower leg level
0.637 0.363 0.000
S85 Injury of blood vessels at lower leg level
0.637 0.363 0.000
S84 Injury of nerves at lower leg level
0.637 0.363 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.637 0.363 0.000
O82 Single delivery by Caesarean section
0.637 0.363 0.000
S20-S29 Injuries to the thorax
0.637 0.363 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.636 0.364 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.636 0.364 0.000
G70-G73 Diseases of myoneural junction and muscle
0.635 0.365 0.000
F32.1 Moderate depressive episode
0.635 0.365 0.000
K09 Cysts of oral region, not elsewhere classified
0.635 0.365 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.635 0.365 0.000
S01 Open wound of head
0.635 0.365 0.000
L89 Decubitus ulcer
0.635 0.365 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.635 0.365 0.000
Z33 Pregnant state, incidental
0.634 0.366 0.000
Q89 Other congenital malformations, not elsewhere classified
0.634 0.366 0.000
N18.5 Chronic kidney disease, stage 5
0.634 0.366 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.633 0.367 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.633 0.367 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.633 0.367 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.633 0.367 0.000
G92 Toxic encephalopathy
0.633 0.367 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.632 0.368 0.000
S00.7 Multiple superficial injuries of head
0.632 0.368 0.000
S00.5 Superficial injury of lip and oral cavity
0.632 0.368 0.000
S00.4 Superficial injury of ear
0.632 0.368 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.632 0.368 0.000
F10.3 Withdrawal state
0.632 0.368 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.632 0.368 0.000
F03 Unspecified dementia
0.631 0.369 0.000
O46.8 Other antepartum haemorrhage
0.631 0.369 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.631 0.369 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.631 0.369 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.631 0.369 0.000
Q35-Q37 Cleft lip and cleft palate
0.631 0.369 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.631 0.369 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.631 0.369 0.000
S02.6 Fracture of mandible
0.630 0.370 0.000
Q50-Q56 Congenital malformations of genital organs
0.630 0.370 0.000
T92 Sequelae of injuries of upper limb
0.630 0.370 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.630 0.370 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.630 0.370 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.629 0.370 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.629 0.370 0.000
L98.5 Mucinosis of skin
0.629 0.370 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.629 0.370 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.629 0.370 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.629 0.370 0.000
L98.1 Factitial dermatitis
0.629 0.370 0.000
B18 Chronic viral hepatitis
0.629 0.371 0.000
Z34.0 Supervision of normal first pregnancy
0.629 0.371 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.627 0.373 0.000
S06 Intracranial injury
0.627 0.373 0.000
K12.2 Cellulitis and abscess of mouth
0.627 0.373 0.000
Z63.9 Problem related to primary support group, unspecified
0.627 0.373 0.000
Z63.7 Other stressful life events affecting family and household
0.627 0.373 0.000
Z63.6 Dependent relative needing care at home
0.627 0.373 0.000
Z63.5 Disruption of family by separation and divorce
0.627 0.373 0.000
Z63.3 Absence of family member
0.627 0.373 0.000
Z63.2 Inadequate family support
0.627 0.373 0.000
Z63.1 Problems in relationship with parents and in-laws
0.627 0.373 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.627 0.373 0.000
K31.6 Fistula of stomach and duodenum
0.626 0.374 0.000
K31.4 Gastric diverticulum
0.626 0.374 0.000
K31.3 Pylorospasm, not elsewhere classified
0.626 0.374 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.626 0.374 0.000
K31.0 Acute dilatation of stomach
0.626 0.374 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.626 0.374 0.000
J00-J06 Acute upper respiratory infections
0.625 0.375 0.000
T42.4 Benzodiazepines
0.625 0.375 0.000
L98.0 Pyogenic granuloma
0.624 0.376 0.000
Z72.2 Drug use
0.624 0.376 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.623 0.377 0.000
S40-S49 Injuries to the shoulder and upper arm
0.622 0.378 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.622 0.378 0.000
K03 Other diseases of hard tissues of teeth
0.622 0.378 0.000
M81 Osteoporosis without pathological fracture
0.622 0.378 0.000
B35 Dermatophytosis
0.622 0.378 0.000
O81 Single delivery by forceps and vacuum extractor
0.621 0.379 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.620 0.380 0.000
O20.8 Other haemorrhage in early pregnancy
0.619 0.381 0.000
G93.0 Cerebral cysts
0.618 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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