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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3733402
log Bayes Factor = 7.06194
Chromosome 4   position 187,158,034  (GRCh37) Explore rs3733402 on Ensembl!
Variant rs3733402 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.997 0.003 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.995 0.005 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.982 0.018 0.000
I80 Phlebitis and thrombophlebitis
0.976 0.024 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.961 0.039 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.833 0.167 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.807 0.193 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.792 0.208 0.000
Z86.7 Personal history of diseases of the circulatory system
0.665 0.335 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.622 0.378 0.000
I26 Pulmonary embolism
0.418 0.582 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.255 0.745 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.118 0.882 0.000
M79.66 Pain in limb (Lower leg)
0.106 0.894 0.000
M79.5 Residual foreign body in soft tissue
0.105 0.895 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.104 0.896 0.000
M79.6 Pain in limb
0.102 0.898 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.101 0.899 0.000
M79.2 Neuralgia and neuritis, unspecified
0.094 0.906 0.000
M79.67 Pain in limb (Ankle and foot)
0.092 0.908 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.091 0.909 0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)
0.089 0.911 0.000
I28 Other diseases of pulmonary vessels
0.088 0.912 0.000
M79.52 Residual foreign body in soft tissue (Upper arm)
0.087 0.913 0.000
M79.1 Myalgia
0.086 0.914 0.000
M79.61 Pain in limb (Shoulder region)
0.084 0.916 0.000
M79.58 Residual foreign body in soft tissue (Other)
0.082 0.918 0.000
M79.3 Panniculitis, unspecified
0.078 0.922 0.000
M79.64 Pain in limb (Hand)
0.077 0.923 0.000
M79.68 Pain in limb (Other)
0.076 0.923 0.000
M79.53 Residual foreign body in soft tissue (Forearm)
0.076 0.924 0.000
M79.63 Pain in limb (Forearm)
0.075 0.925 0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)
0.075 0.925 0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)
0.075 0.925 0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)
0.075 0.925 0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)
0.075 0.925 0.000
M79.10 Myalgia (Multiple sites)
0.075 0.925 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.073 0.927 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.071 0.929 0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)
0.070 0.930 0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)
0.069 0.931 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.069 0.931 0.000
M79.9 Soft tissue disorder, unspecified
0.068 0.932 0.000
M79.7 Fibromyalgia
0.068 0.932 0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)
0.067 0.933 0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)
0.067 0.933 0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)
0.067 0.933 0.000
M79.11 Myalgia (Shoulder region)
0.067 0.933 0.000
M79.56 Residual foreign body in soft tissue (Lower leg)
0.066 0.933 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.066 0.934 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.064 0.936 0.000
M79.18 Myalgia (Other)
0.064 0.936 0.000
M79.8 Other specified soft tissue disorders
0.064 0.936 0.000
I28.1 Aneurysm of pulmonary artery
0.063 0.937 0.000
M79.16 Myalgia (Lower leg)
0.062 0.938 0.000
M79.38 Panniculitis, unspecified (Other)
0.062 0.938 0.000
M79.17 Myalgia (Ankle and foot)
0.062 0.938 0.000
M79.14 Myalgia (Hand)
0.062 0.938 0.000
M79.13 Myalgia (Forearm)
0.062 0.938 0.000
M79.12 Myalgia (Upper arm)
0.062 0.938 0.000
M79.60 Pain in limb (Multiple sites)
0.061 0.939 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.060 0.940 0.000
I28.8 Other specified diseases of pulmonary vessels
0.057 0.942 0.000
M79.19 Myalgia (Site unspecified)
0.057 0.943 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.057 0.943 0.000
M79.39 Panniculitis, unspecified (Site unspecified)
0.056 0.944 0.000
M79.37 Panniculitis, unspecified (Ankle and foot)
0.056 0.944 0.000
M79.36 Panniculitis, unspecified (Lower leg)
0.056 0.944 0.000
M79.35 Panniculitis, unspecified (Pelvic region and thigh)
0.056 0.944 0.000
M79.34 Panniculitis, unspecified (Hand)
0.056 0.944 0.000
M79.33 Panniculitis, unspecified (Forearm)
0.056 0.944 0.000
M79.32 Panniculitis, unspecified (Upper arm)
0.056 0.944 0.000
M79.31 Panniculitis, unspecified (Shoulder region)
0.056 0.944 0.000
M79.30 Panniculitis, unspecified (Multiple sites)
0.056 0.944 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.056 0.944 0.000
M79.69 Pain in limb (Site unspecified)
0.056 0.944 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.055 0.945 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.055 0.945 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.055 0.945 0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)
0.054 0.946 0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)
0.053 0.946 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.053 0.947 0.000
M79.62 Pain in limb (Upper arm)
0.053 0.947 0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec
0.051 0.949 0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)
0.051 0.949 0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)
0.051 0.949 0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)
0.051 0.949 0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)
0.051 0.949 0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)
0.051 0.949 0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)
0.051 0.949 0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)
0.051 0.949 0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)
0.051 0.949 0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)
0.049 0.950 0.000
M79.98 Soft tissue disorder, unspecified (Other)
0.049 0.951 0.000
M79.93 Soft tissue disorder, unspecified (Forearm)
0.049 0.951 0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)
0.049 0.951 0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)
0.049 0.951 0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)
0.049 0.951 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.049 0.951 0.000
M79.78 Fibromyalgia (Other)
0.049 0.951 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.049 0.951 0.000
M79.76 Fibromyalgia (Lower leg)
0.049 0.951 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.049 0.951 0.000
M79.74 Fibromyalgia (Hand)
0.049 0.951 0.000
M79.73 Fibromyalgia (Forearm)
0.049 0.951 0.000
M79.72 Fibromyalgia (Upper arm)
0.049 0.951 0.000
M79.71 Fibromyalgia (Shoulder region)
0.049 0.951 0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)
0.048 0.952 0.000
M79.79 Fibromyalgia (Site unspecified)
0.046 0.954 0.000
M79.70 Fibromyalgia (Multiple sites)
0.046 0.954 0.000
I27 Other pulmonary heart diseases
0.046 0.954 0.000
M79.94 Soft tissue disorder, unspecified (Hand)
0.043 0.957 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.042 0.958 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.038 0.962 0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)
0.035 0.965 0.000
I27.2 Other secondary pulmonary hypertension
0.035 0.965 0.000
M79.88 Other specified soft tissue disorders (Other)
0.033 0.966 0.000
I27.1 Kyphoscoliotic heart disease
0.033 0.967 0.000
I27.9 Pulmonary heart disease, unspecified
0.032 0.968 0.000
M79.0 Rheumatism, unspecified
0.031 0.968 0.000
J30.1 Allergic rhinitis due to pollen
0.000 0.972 0.028
M79.86 Other specified soft tissue disorders (Lower leg)
0.027 0.973 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.027 0.973 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.024 0.976 0.000
I27.8 Other specified pulmonary heart diseases
0.024 0.976 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.024 0.976 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.023 0.977 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.023 0.977 0.000
M79.04 Rheumatism, unspecified (Hand)
0.023 0.977 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.023 0.977 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.023 0.977 0.000
Q21.1 Atrial septal defect
0.022 0.978 0.000
K83.0 Cholangitis
0.022 0.978 0.000
M48.06 Spinal stenosis (Lumbar region)
0.000 0.979 0.021
M79.84 Other specified soft tissue disorders (Hand)
0.021 0.979 0.000
I08.0 Disorders of both mitral and aortic valves
0.021 0.979 0.000
M79.08 Rheumatism, unspecified (Other)
0.021 0.979 0.000
Q21 Congenital malformations of cardiac septa
0.021 0.979 0.000
Q21.0 Ventricular septal defect
0.019 0.981 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.017 0.983 0.000
Q21.3 Tetralogy of Fallot
0.016 0.984 0.000
Q21.8 Other congenital malformations of cardiac septa
0.015 0.985 0.000
Q21.4 Aortopulmonary septal defect
0.015 0.985 0.000
Q21.2 Atrioventricular septal defect
0.015 0.985 0.000
M48.0 Spinal stenosis
0.000 0.985 0.015
M48.09 Spinal stenosis (Site unspecified)
0.000 0.985 0.015
Q24 Other congenital malformations of heart
0.014 0.986 0.000
I27.0 Primary pulmonary hypertension
0.014 0.986 0.000
Q27 Other congenital malformations of peripheral vascular system
0.014 0.986 0.000
H00.1 Chalazion
0.014 0.986 0.000
Q26 Congenital malformations of great veins
0.014 0.986 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.014 0.986 0.000
M48.02 Spinal stenosis (Cervical region)
0.000 0.987 0.013
Z92 Personal history of medical treatment
0.013 0.987 0.000
Q24.5 Malformation of coronary vessels
0.013 0.987 0.000
K05.6 Periodontal disease, unspecified
0.012 0.988 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.012 0.988 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.012 0.988 0.000
Q23 Congenital malformations of aortic and mitral valves
0.012 0.988 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.012 0.988 0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.012 0.988 0.000
Q25 Congenital malformations of great arteries
0.011 0.988 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.011 0.989 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.011 0.989 0.000
Q24.4 Congenital subaortic stenosis
0.011 0.989 0.000
Q24.6 Congenital heart block
0.011 0.989 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.000 0.989 0.011
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.000 0.989 0.011
Q24.0 Dextrocardia
0.011 0.989 0.000
Z92.8 Personal history of other medical treatment
0.011 0.989 0.000
Q28 Other congenital malformations of circulatory system
0.011 0.989 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.011 0.989 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.989 0.011
Q24.3 Pulmonary infundibular stenosis
0.010 0.989 0.000
Q24.2 Cor triatriatum
0.010 0.989 0.000
Q24.1 Levocardia
0.010 0.989 0.000
Z92.5 Personal history of rehabilitation measures
0.010 0.990 0.000
M48.04 Spinal stenosis (Thoracic region)
0.000 0.990 0.010
Q27.4 Congenital phlebectasia
0.010 0.990 0.000
Q27.2 Other congenital malformations of renal artery
0.010 0.990 0.000
Q27.1 Congenital renal artery stenosis
0.010 0.990 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.010 0.990 0.000
Q26.9 Congenital malformation of great vein, unspecified
0.010 0.990 0.000
Q26.8 Other congenital malformations of great veins
0.010 0.990 0.000
Q26.6 Portal vein-hepatic artery fistula
0.010 0.990 0.000
Q26.5 Anomalous portal venous connexion
0.010 0.990 0.000
Q26.3 Partial anomalous pulmonary venous connexion
0.010 0.990 0.000
Q26.2 Total anomalous pulmonary venous connexion
0.010 0.990 0.000
Q26.1 Persistent left superior vena cava
0.010 0.990 0.000
Q26.0 Congenital stenosis of vena cava
0.010 0.990 0.000
Z92.0 Personal history of contraception
0.010 0.990 0.000
I08 Multiple valve diseases
0.010 0.990 0.000
I88 Nonspecific lymphadenitis
0.010 0.990 0.000
Q23.0 Congenital stenosis of aortic valve
0.010 0.990 0.000
Q24.8 Other specified congenital malformations of heart
0.010 0.990 0.000
Q25.4 Other congenital malformations of aorta
0.010 0.990 0.000
Z92.9 Personal history of medical treatment, unspecified
0.010 0.990 0.000
Q23.3 Congenital mitral insufficiency
0.010 0.990 0.000
M13.94 Arthritis, unspecified (Hand)
0.000 0.991 0.009
J30 Vasomotor and allergic rhinitis
0.000 0.991 0.009
Q24.9 Congenital malformation of the heart, unspecified
0.009 0.991 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.000 0.991 0.009
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified
0.009 0.991 0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions
0.009 0.991 0.000
Q20.6 Isomerism of atrial appendages
0.009 0.991 0.000
Q20.5 Discordant atrioventricular connexion
0.009 0.991 0.000
Q20.4 Double inlet ventricle
0.009 0.991 0.000
Q20.3 Discordant ventriculoarterial connexion
0.009 0.991 0.000
Q20.2 Double outlet left ventricle
0.009 0.991 0.000
Q20.1 Double outlet right ventricle
0.009 0.991 0.000
Q20.0 Common arterial trunk
0.009 0.991 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.009 0.991 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.009 0.991 0.000
Q23.4 Hypoplastic left heart syndrome
0.009 0.991 0.000
Q23.2 Congenital mitral stenosis
0.009 0.991 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.009 0.991 0.000
Q22.5 Ebstein's anomaly
0.009 0.991 0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.009 0.991 0.000
Q22.8 Other congenital malformations of tricuspid valve
0.009 0.991 0.000
Q22.6 Hypoplastic right heart syndrome
0.009 0.991 0.000
Q22.4 Congenital tricuspid stenosis
0.009 0.991 0.000
Q22.3 Other congenital malformations of pulmonary valve
0.009 0.991 0.000
Q22.2 Congenital pulmonary valve insufficiency
0.009 0.991 0.000
Q22.0 Pulmonary valve atresia
0.009 0.991 0.000
Q25.6 Stenosis of pulmonary artery
0.009 0.991 0.000
Q27.3 Peripheral arteriovenous malformation
0.009 0.991 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.008 0.991 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.000 0.991 0.008
Q25.3 Stenosis of aorta
0.008 0.991 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.008 0.991 0.000
Q25.8 Other congenital malformations of great arteries
0.008 0.991 0.000
Q25.5 Atresia of pulmonary artery
0.008 0.991 0.000
Q25.2 Atresia of aorta
0.008 0.991 0.000
Q22.1 Congenital pulmonary valve stenosis
0.008 0.991 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.000 0.991 0.008
Z12.0 Special screening examination for neoplasm of stomach
0.009 0.991 0.000
I05-I09 Chronic rheumatic heart diseases
0.008 0.992 0.000
I88.9 Nonspecific lymphadenitis, unspecified
0.008 0.992 0.000
I88.0 Nonspecific mesenteric lymphadenitis
0.008 0.992 0.000
Q28.3 Other malformations of cerebral vessels
0.008 0.992 0.000
Q25.0 Patent ductus arteriosus
0.008 0.992 0.000
M48 Other spondylopathies
0.000 0.992 0.008
Z00.5 Examination of potential donor of organ and tissue
0.000 0.992 0.008
Q28.9 Congenital malformation of circulatory system, unspecified
0.008 0.992 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.008 0.992 0.000
Q28.1 Other malformations of precerebral vessels
0.008 0.992 0.000
Chapter IX Diseases of the circulatory system
0.008 0.992 0.000
J30.4 Allergic rhinitis, unspecified
0.000 0.992 0.008
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.008 0.992 0.000
Q65 Congenital deformities of hip
0.008 0.992 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.008 0.992 0.000
J30.0 Vasomotor rhinitis
0.000 0.992 0.008
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.008 0.992 0.000
I06 Rheumatic aortic valve diseases
0.007 0.993 0.000
I88.8 Other nonspecific lymphadenitis
0.007 0.993 0.000
Q65.8 Other congenital deformities of hip
0.007 0.993 0.000
I88.1 Chronic lymphadenitis, except mesenteric
0.007 0.993 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.000 0.993 0.007
M48.00 Spinal stenosis (Multiple sites in spine)
0.000 0.993 0.007
Q28.2 Arteriovenous malformation of cerebral vessels
0.007 0.993 0.000
Q28.0 Arteriovenous malformation of precerebral vessels
0.007 0.993 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.007 0.993 0.000
Q74 Other congenital malformations of limb(s)
0.007 0.993 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.007 0.993 0.000
Q66 Congenital deformities of feet
0.007 0.993 0.000
M70.22 Olecranon bursitis-Upper arm
0.007 0.993 0.000
I86 Varicose veins of other sites
0.007 0.993 0.000
Q78 Other osteochondrodysplasias
0.007 0.993 0.000
I09 Other rheumatic heart diseases
0.006 0.993 0.000
N64.8 Other specified disorders of breast
0.007 0.993 0.000
H72 Perforation of tympanic membrane
0.000 0.994 0.006
Q65.0 Congenital dislocation of hip, unilateral
0.006 0.994 0.000
H72.0 Central perforation of tympanic membrane
0.000 0.994 0.006
Q65.2 Congenital dislocation of hip, unspecified
0.006 0.994 0.000
Q23.1 Congenital insufficiency of aortic valve
0.006 0.994 0.000
I06.0 Rheumatic aortic stenosis
0.006 0.994 0.000
I08.8 Other multiple valve diseases
0.006 0.994 0.000
M70-M79 Other soft tissue disorders
0.006 0.994 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.006 0.994 0.000
M70.2 Olecranon bursitis
0.006 0.994 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.000 0.994 0.006
H72.8 Other perforations of tympanic membrane
0.000 0.994 0.006
Q74.1 Congenital malformation of knee
0.006 0.994 0.000
M48.4 Fatigue fracture of vertebra
0.000 0.994 0.006
M48.3 Traumatic spondylopathy
0.000 0.994 0.006
M48.2 Kissing spine
0.000 0.994 0.006
M48.1 Ankylosing hyperostosis [Forestier]
0.000 0.994 0.006
I08.9 Multiple valve disease, unspecified
0.006 0.994 0.000
J30.2 Other seasonal allergic rhinitis
0.000 0.994 0.006
Q66.9 Congenital deformity of feet, unspecified
0.006 0.994 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.000 0.994 0.006
I06.1 Rheumatic aortic insufficiency
0.006 0.994 0.000
Q76 Congenital malformations of spine and bony thorax
0.006 0.994 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.000 0.994 0.006
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.006 0.994 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.000 0.994 0.006
Q75 Other congenital malformations of skull and face bones
0.006 0.994 0.000
Q73 Reduction defects of unspecified limb
0.006 0.994 0.000
Q72 Reduction defects of lower limb
0.006 0.994 0.000
Q71 Reduction defects of upper limb
0.006 0.994 0.000
Q69 Polydactyly
0.006 0.994 0.000
I86.1 Scrotal varices
0.006 0.994 0.000
Q65.9 Congenital deformity of hip, unspecified
0.006 0.994 0.000
Q65.6 Unstable hip
0.006 0.994 0.000
Q65.5 Congenital subluxation of hip, unspecified
0.006 0.994 0.000
Q65.4 Congenital subluxation of hip, bilateral
0.006 0.994 0.000
Q65.3 Congenital subluxation of hip, unilateral
0.006 0.994 0.000
Q70 Syndactyly
0.006 0.994 0.000
Q00-Q07 Congenital malformations of the nervous system
0.006 0.994 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.006 0.994 0.000
I81 Portal vein thrombosis
0.006 0.994 0.000
Q65.1 Congenital dislocation of hip, bilateral
0.006 0.994 0.000
H00 Hordeolum and chalazion
0.006 0.994 0.000
I00-I02 Acute rheumatic fever
0.006 0.994 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.006 0.994 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.006 0.994 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.006 0.994 0.000
Q25.1 Coarctation of aorta
0.005 0.994 0.001
M48.8 Other specified spondylopathies
0.000 0.994 0.006
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.006 0.994 0.000
M48.9 Spondylopathy, unspecified
0.000 0.994 0.005
Q68 Other congenital musculoskeletal deformities
0.006 0.994 0.000
I07 Rheumatic tricuspid valve diseases
0.006 0.994 0.000
I06.8 Other rheumatic aortic valve diseases
0.005 0.994 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.005 0.994 0.000
H73.8 Other specified disorders of tympanic membrane
0.000 0.994 0.006
Q78.0 Osteogenesis imperfecta
0.005 0.994 0.000
H72.1 Attic perforation of tympanic membrane
0.000 0.994 0.005
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.000 0.994 0.005
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.000 0.994 0.005
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.000 0.994 0.005
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.000 0.994 0.005
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.000 0.994 0.005
Q66.8 Other congenital deformities of feet
0.005 0.995 0.000
H74 Other disorders of middle ear and mastoid
0.000 0.995 0.005
H65-H75 Diseases of middle ear and mastoid
0.000 0.995 0.005
Q38-Q45 Other congenital malformations of the digestive system
0.005 0.995 0.000
Q66.7 Pes cavus
0.005 0.995 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.005 0.995 0.000
Q78.2 Osteopetrosis
0.005 0.995 0.000
H72.2 Other marginal perforations of tympanic membrane
0.000 0.995 0.005
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.005 0.995 0.000
Q66.3 Other congenital varus deformities of feet
0.005 0.995 0.000
Q74.9 Unspecified congenital malformation of limb(s)
0.005 0.995 0.000
Q74.8 Other specified congenital malformations of limb(s)
0.005 0.995 0.000
Q74.3 Arthrogryposis multiplex congenita
0.005 0.995 0.000
H73 Other disorders of tympanic membrane
0.000 0.995 0.005
H71 Cholesteatoma of middle ear
0.000 0.995 0.005
I09.9 Rheumatic heart disease, unspecified
0.005 0.995 0.000
I86.2 Pelvic varices
0.005 0.995 0.000
H74.4 Polyp of middle ear
0.000 0.995 0.005
Q30-Q34 Congenital malformations of the respiratory system
0.005 0.995 0.000
Q80-Q89 Other congenital malformations
0.005 0.995 0.000
Q66.5 Congenital pes planus
0.005 0.995 0.000
Q66.4 Talipes calcaneovalgus
0.005 0.995 0.000
Q66.1 Talipes calcaneovarus
0.005 0.995 0.000
Q78.9 Osteochondrodysplasia, unspecified
0.005 0.995 0.000
Q78.8 Other specified osteochondrodysplasias
0.005 0.995 0.000
Q78.6 Multiple congenital exostoses
0.005 0.995 0.000
Q78.5 Metaphyseal dysplasia
0.005 0.995 0.000
Q78.4 Enchondromatosis
0.005 0.995 0.000
Q78.3 Progressive diaphyseal dysplasia
0.005 0.995 0.000
Q78.1 Polyostotic fibrous dysplasia
0.005 0.995 0.000
I86.0 Sublingual varices
0.005 0.995 0.000
Q79.6 Ehlers-Danlos syndrome
0.005 0.995 0.000
M70.23 Olecranon bursitis-Forearm
0.005 0.995 0.000
I09.8 Other specified rheumatic heart diseases
0.005 0.995 0.000
I09.2 Chronic rheumatic pericarditis
0.005 0.995 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.005 0.995 0.000
I09.0 Rheumatic myocarditis
0.005 0.995 0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.005 0.995 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.995 0.005
Q43 Other congenital malformations of intestine
0.005 0.995 0.000
Q66.0 Talipes equinovarus
0.005 0.995 0.000
Q05 Spina bifida
0.005 0.995 0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.995 0.005
Q76.0 Spina bifida occulta
0.005 0.995 0.000
Q06 Other congenital malformations of spinal cord
0.005 0.995 0.000
H74.1 Adhesive middle ear disease
0.000 0.995 0.005
Q79.0 Congenital diaphragmatic hernia
0.005 0.995 0.000
Q76.5 Cervical rib
0.005 0.995 0.000
Q43.0 Meckel's diverticulum
0.005 0.995 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.005 0.995 0.000
Q07 Other congenital malformations of nervous system
0.005 0.995 0.000
Q67.5 Congenital deformity of spine
0.005 0.995 0.000
Q03 Congenital hydrocephalus
0.005 0.995 0.000
M70.29 Olecranon bursitis-Site unspec
0.005 0.995 0.000
M70.28 Olecranon bursitis-Other
0.005 0.995 0.000
M70.27 Olecranon bursitis-Ankle/Foot
0.005 0.995 0.000
M70.26 Olecranon bursitis-Lower Leg
0.005 0.995 0.000
M70.25 Olecranon bursitis-Pelvic/Thigh
0.005 0.995 0.000
M70.24 Olecranon bursitis-Hand
0.005 0.995 0.000
M70.21 Olecranon bursitis-Shldr region
0.005 0.995 0.000
M70.20 Olecranon bursitis-Mult sites
0.005 0.995 0.000
I87 Other disorders of veins
0.004 0.995 0.001
M76 Enthesopathies of lower limb, excluding foot
0.005 0.995 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.000 0.995 0.004
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.000 0.995 0.004
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.000 0.995 0.004
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.000 0.995 0.004
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.000 0.995 0.004
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.000 0.995 0.004
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.000 0.995 0.004
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.000 0.995 0.004
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.000 0.995 0.004
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.000 0.995 0.004
M48.29 Kissing spine (Site unspecified)
0.000 0.995 0.004
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.000 0.995 0.004
M48.27 Kissing spine (Lumbosacral region)
0.000 0.995 0.004
M48.26 Kissing spine (Lumbar region)
0.000 0.995 0.004
M48.25 Kissing spine (Thoracolumbar region)
0.000 0.995 0.004
M48.24 Kissing spine (Thoracic region)
0.000 0.995 0.004
M48.23 Kissing spine (Cervicothoracic region)
0.000 0.995 0.004
M48.22 Kissing spine (Cervical region)
0.000 0.995 0.004
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.000 0.995 0.004
M48.20 Kissing spine (Multiple sites in spine)
0.000 0.995 0.004
M48.39 Traumatic spondylopathy (Site unspecified)
0.000 0.995 0.004
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.000 0.995 0.004
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.000 0.995 0.004
M48.36 Traumatic spondylopathy (Lumbar region)
0.000 0.995 0.004
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.000 0.995 0.004
M48.34 Traumatic spondylopathy (Thoracic region)
0.000 0.995 0.004
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.000 0.995 0.004
M48.32 Traumatic spondylopathy (Cervical region)
0.000 0.995 0.004
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.000 0.995 0.004
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.000 0.995 0.004
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.000 0.995 0.004
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.000 0.995 0.004
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.000 0.995 0.004
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.000 0.995 0.004
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.000 0.995 0.004
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.000 0.995 0.004
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.000 0.995 0.004
M48.42 Fatigue fracture of vertebra (Cervical region)
0.000 0.995 0.004
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.000 0.995 0.004
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.000 0.995 0.004
M70.5 Other bursitis of knee
0.005 0.995 0.000
Q45 Other congenital malformations of digestive system
0.005 0.995 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.995 0.005
Q66.2 Metatarsus varus
0.004 0.995 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.000 0.995 0.004
Q76.9 Congenital malformation of bony thorax, unspecified
0.004 0.995 0.000
Q76.8 Other congenital malformations of bony thorax
0.004 0.995 0.000
Q76.7 Congenital malformation of sternum
0.004 0.995 0.000
Q76.6 Other congenital malformations of ribs
0.004 0.995 0.000
Q76.3 Congenital scoliosis due to congenital bony malformation
0.004 0.995 0.000
Q76.2 Congenital spondylolisthesis
0.004 0.995 0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified
0.004 0.995 0.000
Q79.5 Other congenital malformations of abdominal wall
0.004 0.995 0.000
Q79.4 Prune belly syndrome
0.004 0.995 0.000
Q79.3 Gastroschisis
0.004 0.995 0.000
Q79.2 Exomphalos
0.004 0.995 0.000
Q69.9 Polydactyly, unspecified
0.004 0.995 0.000
Q69.2 Accessory toe(s)
0.004 0.995 0.000
Q69.1 Accessory thumb(s)
0.004 0.995 0.000
Q69.0 Accessory finger(s)
0.004 0.995 0.000
Q71.9 Reduction defect of upper limb, unspecified
0.004 0.995 0.000
Q71.8 Other reduction defects of upper limb(s)
0.004 0.995 0.000
Q71.6 Lobster-claw hand
0.004 0.995 0.000
Q71.5 Longitudinal reduction defect of ulna
0.004 0.995 0.000
Q71.4 Longitudinal reduction defect of radius
0.004 0.995 0.000
Q71.3 Congenital absence of hand and finger(s)
0.004 0.995 0.000
Q71.2 Congenital absence of both forearm and hand
0.004 0.995 0.000
Q71.1 Congenital absence of upper arm and forearm with hand present
0.004 0.995 0.000
Q71.0 Congenital complete absence of upper limb(s)
0.004 0.995 0.000
Q72.9 Reduction defect of lower limb, unspecified
0.004 0.995 0.000
Q72.8 Other reduction defects of lower limb(s)
0.004 0.995 0.000
Q72.7 Split foot
0.004 0.995 0.000
Q72.6 Longitudinal reduction defect of fibula
0.004 0.995 0.000
Q72.5 Longitudinal reduction defect of tibia
0.004 0.995 0.000
Q72.4 Longitudinal reduction defect of femur
0.004 0.995 0.000
Q72.3 Congenital absence of foot and toe(s)
0.004 0.995 0.000
Q72.2 Congenital absence of both lower leg and foot
0.004 0.995 0.000
Q72.1 Congenital absence of thigh and lower leg with foot present
0.004 0.995 0.000
Q72.0 Congenital complete absence of lower limb(s)
0.004 0.995 0.000
Q73.8 Other reduction defects of unspecified limb(s)
0.004 0.995 0.000
Q73.1 Phocomelia, unspecified limb(s)
0.004 0.995 0.000
Q73.0 Congenital absence of unspecified limb(s)
0.004 0.995 0.000
Q75.9 Congenital malformation of skull and face bones, unspecified
0.004 0.995 0.000
Q75.8 Other specified congenital malformations of skull and face bones
0.004 0.995 0.000
Q75.5 Oculomandibular dysostosis
0.004 0.995 0.000
Q75.4 Mandibulofacial dysostosis
0.004 0.995 0.000
Q75.3 Macrocephaly
0.004 0.995 0.000
Q75.2 Hypertelorism
0.004 0.995 0.000
Q75.1 Craniofacial dysostosis
0.004 0.995 0.000
Q75.0 Craniosynostosis
0.004 0.995 0.000
Q39 Congenital malformations of oesophagus
0.004 0.995 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.004 0.995 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.004 0.995 0.000
Q01 Encephalocele
0.004 0.995 0.000
Q00 Anencephaly and similar malformations
0.004 0.995 0.000
Q02 Microcephaly
0.004 0.995 0.000
Q70.9 Syndactyly, unspecified
0.004 0.996 0.000
Q70.4 Polysyndactyly
0.004 0.996 0.000
Q70.2 Fused toes
0.004 0.996 0.000
Q70.1 Webbed fingers
0.004 0.996 0.000
Q70.0 Fused fingers
0.004 0.996 0.000
Q82 Other congenital malformations of skin
0.004 0.996 0.000
H73.1 Chronic myringitis
0.000 0.996 0.004
Q67.8 Other congenital deformities of chest
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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