TreeWAS – Variant ID: rs3745672

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.55 Pain in joint (Pelvic region and thigh)	0.021	0.979	0.000
C44.2 Skin of ear and external auricular canal	0.012	0.988	0.000
C44 Other malignant neoplasms of skin	0.012	0.988	0.000
C44.5 Skin of trunk	0.011	0.989	0.000
C44.0 Skin of lip	0.011	0.989	0.000
C44.3 Skin of other and unspecified parts of face	0.010	0.990	0.000
C44.6 Skin of upper limb, including shoulder	0.009	0.990	0.000
C44.7 Skin of lower limb, including hip	0.009	0.991	0.000
H65.3 Chronic mucoid otitis media	0.009	0.991	0.000
M25.5 Pain in joint	0.009	0.991	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.008	0.991	0.000
C44.8 Overlapping lesion of skin	0.008	0.991	0.000
C44.1 Skin of eyelid, including canthus	0.008	0.992	0.000
M25 Other joint disorders, not elsewhere classified	0.008	0.992	0.000
H65 Nonsuppurative otitis media	0.007	0.992	0.000
M25.76 Osteophyte (Lower leg)	0.007	0.993	0.000
M25.7 Osteophyte	0.007	0.993	0.000
M25.50 Pain in joint (Multiple sites)	0.007	0.993	0.000
M25.59 Pain in joint (Site unspecified)	0.007	0.993	0.000
M25.8 Other specified joint disorders	0.007	0.993	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.007	0.993	0.000
Y43 Primarily systemic agents	0.007	0.993	0.000
M25.58 Pain in joint (Other)	0.007	0.993	0.000
M25.52 Pain in joint (Upper arm)	0.007	0.993	0.000
M25.56 Pain in joint (Lower leg)	0.007	0.993	0.000
H65.4 Other chronic nonsuppurative otitis media	0.006	0.994	0.000
M25.4 Effusion of joint	0.006	0.994	0.000
M25.72 Osteophyte (Upper arm)	0.006	0.994	0.000
M25.86 Other specified joint disorders (Lower leg)	0.006	0.994	0.000
Y43.3 Other antineoplastic drugs	0.006	0.994	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
M25.9 Joint disorder, unspecified	0.006	0.994	0.000
M25.3 Other instability of joint	0.006	0.994	0.000
M25.2 Flail joint	0.006	0.994	0.000
M25.1 Fistula of joint	0.006	0.994	0.000
M25.0 Haemarthrosis	0.006	0.994	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.006	0.994	0.000
Y52 Agents primarily affecting the cardiovascular system	0.006	0.994	0.000
M25.77 Osteophyte (Ankle and foot)	0.006	0.994	0.000
M25.47 Effusion of joint (Ankle and foot)	0.006	0.994	0.000
H65.2 Chronic serous otitis media	0.006	0.994	0.000
H65.1 Other acute nonsuppurative otitis media	0.006	0.994	0.000
H65.0 Acute serous otitis media	0.006	0.994	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.006	0.994	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.006	0.994	0.000
Y48 Anaesthetics and therapeutic gases	0.006	0.994	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.006	0.994	0.000
Y43.4 Immunosuppressive agents	0.005	0.994	0.000
M25.79 Osteophyte (Site unspecified)	0.005	0.994	0.000
M25.74 Osteophyte (Hand)	0.005	0.994	0.000
M25.73 Osteophyte (Forearm)	0.005	0.994	0.000
M25.71 Osteophyte (Shoulder region)	0.005	0.994	0.000
M25.70 Osteophyte (Multiple sites)	0.005	0.994	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.005	0.994	0.000
Y43.0 Antiallergic and antiemetic drugs	0.005	0.994	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.005	0.994	0.000
M25.54 Pain in joint (Hand)	0.005	0.995	0.000
Y44 Agents primarily affecting blood constituents	0.005	0.995	0.000
Y40 Systemic antibiotics	0.005	0.995	0.000
M25.53 Pain in joint (Forearm)	0.005	0.995	0.000
H65-H75 Diseases of middle ear and mastoid	0.005	0.995	0.000
Y42.7 Androgens and anabolic congeners	0.005	0.995	0.000
M25.84 Other specified joint disorders (Hand)	0.005	0.995	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.005	0.995	0.000
M25.88 Other specified joint disorders (Other)	0.005	0.995	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.005	0.995	0.000
M25.83 Other specified joint disorders (Forearm)	0.005	0.995	0.000
M25.82 Other specified joint disorders (Upper arm)	0.005	0.995	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.005	0.995	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.005	0.995	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.005	0.995	0.000
Y59 Other and unspecified vaccines and biological substances	0.005	0.995	0.000
Y58 Bacterial vaccines	0.005	0.995	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.005	0.995	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.005	0.995	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.005	0.995	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.005	0.995	0.000
Y43.9 Primarily systemic agent, unspecified	0.005	0.995	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.005	0.995	0.000
Y43.6 Enzymes, not elsewhere classified	0.005	0.995	0.000
Y43.5 Acidifying and alkalising agents	0.005	0.995	0.000
Y43.2 Antineoplastic natural products	0.005	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.005	0.995	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.005	0.995	0.000
M25.49 Effusion of joint (Site unspecified)	0.005	0.995	0.000
M25.48 Effusion of joint (Other)	0.005	0.995	0.000
M25.44 Effusion of joint (Hand)	0.005	0.995	0.000
M25.43 Effusion of joint (Forearm)	0.005	0.995	0.000
M25.42 Effusion of joint (Upper arm)	0.005	0.995	0.000
M25.41 Effusion of joint (Shoulder region)	0.005	0.995	0.000
M25.40 Effusion of joint (Multiple sites)	0.005	0.995	0.000
Y48.3 Local anaesthetics	0.005	0.995	0.000
Y57 Other and unspecified drugs and medicaments	0.005	0.995	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
M25.57 Pain in joint (Ankle and foot)	0.005	0.995	0.000
Y42.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.005	0.995	0.000
Y42.4 Oral contraceptives	0.005	0.995	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.000
Y42.2 Antithyroid drugs	0.005	0.995	0.000
Y42.1 Thyroid hormones and substitutes	0.005	0.995	0.000
Y52.1 Calcium-channel blockers	0.005	0.995	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
Y54.5 Other diuretics	0.005	0.995	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.004	0.995	0.000
H71 Cholesteatoma of middle ear	0.005	0.995	0.000
Y49.2 Other and unspecified antidepressants	0.004	0.995	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.995	0.000
Y54.3 Benzothiadiazine derivatives	0.004	0.995	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.995	0.000
W20-W49 Exposure to inanimate mechanical forces	0.005	0.995	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.995	0.000
Y40.0 Penicillins	0.004	0.995	0.000
Chapter XX External causes of morbidity and mortality	0.005	0.995	0.000
M25.09 Haemarthrosis (Site unspecified)	0.004	0.995	0.000
M25.08 Haemarthrosis (Other)	0.004	0.995	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.004	0.995	0.000
M25.06 Haemarthrosis (Lower leg)	0.004	0.995	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.004	0.995	0.000
M25.04 Haemarthrosis (Hand)	0.004	0.995	0.000
M25.03 Haemarthrosis (Forearm)	0.004	0.995	0.000
M25.02 Haemarthrosis (Upper arm)	0.004	0.995	0.000
M25.01 Haemarthrosis (Shoulder region)	0.004	0.995	0.000
M25.00 Haemarthrosis (Multiple sites)	0.004	0.995	0.000
M25.19 Fistula of joint (Site unspecified)	0.004	0.995	0.000
M25.18 Fistula of joint (Other)	0.004	0.995	0.000
M25.17 Fistula of joint (Ankle and foot)	0.004	0.995	0.000
M25.16 Fistula of joint (Lower leg)	0.004	0.995	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.004	0.995	0.000
M25.14 Fistula of joint (Hand)	0.004	0.995	0.000
M25.13 Fistula of joint (Forearm)	0.004	0.995	0.000
M25.12 Fistula of joint (Upper arm)	0.004	0.995	0.000
M25.11 Fistula of joint (Shoulder region)	0.004	0.995	0.000
M25.10 Fistula of joint (Multiple sites)	0.004	0.995	0.000
M25.29 Flail joint (Site unspecified)	0.004	0.995	0.000
M25.28 Flail joint (Other)	0.004	0.995	0.000
M25.27 Flail joint (Ankle and foot)	0.004	0.995	0.000
M25.26 Flail joint (Lower leg)	0.004	0.995	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.004	0.995	0.000
M25.24 Flail joint (Hand)	0.004	0.995	0.000
M25.23 Flail joint (Forearm)	0.004	0.995	0.000
M25.22 Flail joint (Upper arm)	0.004	0.995	0.000
M25.21 Flail joint (Shoulder region)	0.004	0.995	0.000
M25.20 Flail joint (Multiple sites)	0.004	0.995	0.000
M25.39 Other instability of joint (Site unspecified)	0.004	0.995	0.000
M25.38 Other instability of joint (Other)	0.004	0.995	0.000
M25.37 Other instability of joint (Ankle and foot)	0.004	0.995	0.000
M25.36 Other instability of joint (Lower leg)	0.004	0.995	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.004	0.995	0.000
M25.34 Other instability of joint (Hand)	0.004	0.995	0.000
M25.33 Other instability of joint (Forearm)	0.004	0.995	0.000
M25.32 Other instability of joint (Upper arm)	0.004	0.995	0.000
M25.31 Other instability of joint (Shoulder region)	0.004	0.995	0.000
M25.30 Other instability of joint (Multiple sites)	0.004	0.995	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.004	0.995	0.000
M25.98 Joint disorder, unspecified (Other)	0.004	0.995	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.004	0.995	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.004	0.995	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.004	0.995	0.000
M25.94 Joint disorder, unspecified (Hand)	0.004	0.995	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.004	0.995	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.004	0.995	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.004	0.995	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.004	0.995	0.000
C44.4 Skin of scalp and neck	0.004	0.996	0.000
Y42.5 Other oestrogens and progestogens	0.004	0.996	0.000
Y44.2 Anticoagulants	0.004	0.996	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
H74 Other disorders of middle ear and mastoid	0.004	0.996	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.004	0.996	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
Y54.9 Mineral salts, not elsewhere classified	0.004	0.996	0.000
Y54.8 Agents affecting uric acid metabolism	0.004	0.996	0.000
Y54.7 Agents affecting calcification	0.004	0.996	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
Y54.4 Loop [high-ceiling] diuretics	0.004	0.996	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.004	0.996	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.004	0.996	0.000
Y54.0 Mineralocorticoids	0.004	0.996	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.004	0.996	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.004	0.996	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.004	0.996	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
K63.8 Other specified diseases of intestine	0.000	0.996	0.004
Y48.5 Therapeutic gases	0.004	0.996	0.000
Y48.4 Anaesthetic, unspecified	0.004	0.996	0.000
Y48.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
Y48.1 Parenteral anaesthetics	0.004	0.996	0.000
Y48.0 Inhaled anaesthetics	0.004	0.996	0.000
W29 Contact with other powered hand tools and household machinery	0.004	0.996	0.000
Y49.9 Psychotropic drug, unspecified	0.004	0.996	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
Y49.7 Psychostimulants with abuse potential	0.004	0.996	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.004	0.996	0.000
Y49.5 Other antipsychotics and neuroleptics	0.004	0.996	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.004	0.996	0.000
W22 Striking against or struck by other objects	0.004	0.996	0.000
W29.9 Unspecified place	0.004	0.996	0.000
M25.78 Osteophyte (Other)	0.004	0.996	0.000
Y40.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
Y40.6 Rifamycins	0.004	0.996	0.000
Y40.5 Aminoglycosides	0.004	0.996	0.000
Y40.4 Tetracyclines	0.004	0.996	0.000
Y40.3 Macrolides	0.004	0.996	0.000
Y40.2 Chloramphenicol group	0.004	0.996	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.004	0.996	0.000
Y44.7 Plasma substitutes	0.004	0.996	0.000
Y44.6 Natural blood and blood products	0.004	0.996	0.000
Y44.5 Thrombolytic drugs	0.004	0.996	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.004	0.996	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.004	0.996	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.004	0.996	0.000
H66 Suppurative and unspecified otitis media	0.004	0.996	0.000
H73 Other disorders of tympanic membrane	0.004	0.996	0.000
Y86 Sequelae of other accidents	0.004	0.996	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.004	0.996	0.000
H68 Eustachian salpingitis and obstruction	0.004	0.996	0.000
H67 Otitis media in diseases classified elsewhere	0.004	0.996	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.004	0.996	0.000
W22.9 Unspecified place	0.004	0.996	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
X60-X84 Intentional self-harm	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.004	0.996	0.000
Y46.8 Antispasticity drugs	0.004	0.996	0.000
Y46.7 Anti-Parkinsonism drugs	0.004	0.996	0.000
Y46.6 Other and unspecified antiepileptics	0.004	0.996	0.000
Y46.5 Valproic acid	0.004	0.996	0.000
Y46.4 Iminostilbenes	0.004	0.996	0.000
Y46.3 Deoxybarbiturates	0.004	0.996	0.000
Y46.2 Hydantoin derivatives	0.004	0.996	0.000
Y46.1 Oxazolidinediones	0.004	0.996	0.000
Y46.0 Succinimides	0.004	0.996	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.004	0.996	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.004	0.996	0.000
Y47.4 Bromine compounds	0.004	0.996	0.000
Y47.3 Paraldehyde	0.004	0.996	0.000
Y47.2 Chloral derivatives	0.004	0.996	0.000
Y47.1 Benzodiazepines	0.004	0.996	0.000
Y47.0 Barbiturates, not elsewhere classified	0.004	0.996	0.000
Y50.9 Central nervous system stimulant, unspecified	0.004	0.996	0.000
Y50.8 Other central nervous system stimulants	0.004	0.996	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.004	0.996	0.000
Y50.1 Opioid receptor antagonists	0.004	0.996	0.000
Y50.0 Analeptics	0.004	0.996	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
Y53.7 Emetics	0.004	0.996	0.000
Y53.6 Antidiarrhoeal drugs	0.004	0.996	0.000
Y53.5 Digestants	0.004	0.996	0.000
Y53.4 Other laxatives	0.004	0.996	0.000
Y53.3 Saline and osmotic laxatives	0.004	0.996	0.000
Y53.2 Stimulant laxatives	0.004	0.996	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
Y53.0 Histamine H2-receptor antagonists	0.004	0.996	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
Y55.5 Anticommon cold drugs	0.004	0.996	0.000
Y55.4 Expectorants	0.004	0.996	0.000
Y55.3 Antitussives	0.004	0.996	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
Y55.0 Oxytocic drugs	0.004	0.996	0.000
Y56.9 Topical agent, unspecified	0.004	0.996	0.000
Y56.8 Other topical agents	0.004	0.996	0.000
Y56.7 Dental drugs, topically applied	0.004	0.996	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
Y56.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
Y56.3 Emollients, demulcents and protectants	0.004	0.996	0.000
Y56.2 Local astringents and local detergents	0.004	0.996	0.000
Y56.1 Antipruritics	0.004	0.996	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
Y58.9 Other and unspecified bacterial vaccines	0.004	0.996	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.004	0.996	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.004	0.996	0.000
Y58.5 Diphtheria vaccine	0.004	0.996	0.000
Y58.4 Tetanus vaccine	0.004	0.996	0.000
Y58.3 Plague vaccine	0.004	0.996	0.000
Y58.2 Cholera vaccine	0.004	0.996	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.004	0.996	0.000
Y58.0 BCG vaccine	0.004	0.996	0.000
Y59.9 Vaccine or biological substance, unspecified	0.004	0.996	0.000
Y59.8 Other specified vaccines and biological substances	0.004	0.996	0.000
Y59.3 Immunoglobulin	0.004	0.996	0.000
Y59.2 Protozoal vaccines	0.004	0.996	0.000
Y59.1 Rickettsial vaccines	0.004	0.996	0.000
Y59.0 Viral vaccines	0.004	0.996	0.000
W21 Striking against or struck by sports equipment	0.004	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
Y41.5 Antiviral drugs	0.004	0.996	0.000
Y41.4 Anthelminthics	0.004	0.996	0.000
Y41.3 Other antiprotozoal drugs	0.004	0.996	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
Y41.1 Antimycobacterial drugs	0.004	0.996	0.000
Y41.0 Sulphonamides	0.004	0.996	0.000
H69 Other disorders of Eustachian tube	0.004	0.996	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.004	0.996	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
H93.1 Tinnitus	0.004	0.996	0.000
Y57.8 Other drugs and medicaments	0.003	0.996	0.000
Y57.7 Vitamins, not elsewhere classified	0.003	0.996	0.000
Y57.6 Other diagnostic agents	0.003	0.996	0.000
Y57.5 X-ray contrast media	0.003	0.996	0.000
Y57.4 Pharmaceutical excipients	0.003	0.996	0.000
Y57.3 Alcohol deterrents	0.003	0.996	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.003	0.996	0.000
Y57.1 Lipotropic drugs	0.003	0.996	0.000
Y57.0 Appetite depressants [anorectics]	0.003	0.996	0.000
D05 Carcinoma in situ of breast	0.004	0.996	0.000
Y60.0 During surgical operation	0.004	0.996	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.003	0.996	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.996	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.996	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.996	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.996	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.996	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.996	0.000
Y51.0 Anticholinesterase agents	0.003	0.996	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.996	0.000
Y89 Sequelae of other external causes	0.003	0.996	0.000
V20-V29 Motorcycle rider injured in transport accident	0.004	0.996	0.000
H74.0 Tympanosclerosis	0.003	0.996	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.996	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.996	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.996	0.000
Y45.4 Antirheumatics	0.003	0.996	0.000
Y45.2 Propionic acid derivatives	0.003	0.996	0.000
Y45.1 Salicylates	0.003	0.996	0.000
Y45.0 Opioids and related analgesics	0.003	0.996	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.003	0.996	0.000
W46 Contact with hypodermic needle	0.003	0.996	0.000
W45 Foreign body or object entering through skin	0.003	0.996	0.000
W43 Exposure to vibration	0.003	0.996	0.000
W42 Exposure to noise	0.003	0.996	0.000
W41 Exposure to high-pressure jet	0.003	0.996	0.000
W40 Explosion of other materials	0.003	0.996	0.000
W39 Discharge of firework	0.003	0.996	0.000
W38 Explosion and rupture of other specified pressurised devices	0.003	0.996	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.003	0.996	0.000
W36 Explosion and rupture of gas cylinder	0.003	0.996	0.000
W35 Explosion and rupture of boiler	0.003	0.996	0.000
W34 Discharge from other and unspecified firearms	0.003	0.996	0.000
W33 Rifle, shotgun and larger firearm discharge	0.003	0.996	0.000
W32 Handgun discharge	0.003	0.996	0.000
W31 Contact with other and unspecified machinery	0.003	0.996	0.000
W30 Contact with agricultural machinery	0.003	0.996	0.000
W28 Contact with powered lawn mower	0.003	0.996	0.000
W27 Contact with nonpowered hand tool	0.003	0.996	0.000
W26 Contact with knife, sword or dagger	0.003	0.996	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.003	0.996	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.003	0.996	0.000
W20 Struck by thrown, projected or falling object	0.003	0.996	0.000
W50-W64 Exposure to animate mechanical forces	0.003	0.996	0.000
D05.1 Intraductal carcinoma in situ	0.004	0.996	0.000
Y35-Y36 Legal intervention and operations of war	0.003	0.996	0.000
Y10-Y34 Event of undetermined intent	0.003	0.996	0.000
Y00-Y09 Assault	0.003	0.996	0.000
X85-X99 Assault	0.003	0.996	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.003	0.996	0.000
X50-X57 Overexertion, travel and privation	0.003	0.996	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.003	0.996	0.000
X30-X39 Exposure to forces of nature	0.003	0.996	0.000
X20-X29 Contact with venomous animals and plants	0.003	0.996	0.000
X10-X19 Contact with heat and hot substances	0.003	0.996	0.000
X00-X09 Exposure to smoke, fire and flames	0.003	0.996	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.003	0.996	0.000
W75-W84 Other accidental threats to breathing	0.003	0.996	0.000
W65-W74 Accidental drowning and submersion	0.003	0.996	0.000
V98-V99 Other and unspecified transport accidents	0.003	0.996	0.000
V95-V97 Air and space transport accidents	0.003	0.996	0.000
V90-V94 Water transport accidents	0.003	0.996	0.000
V80-V89 Other land transport accidents	0.003	0.996	0.000
V70-V79 Bus occupant injured in transport accident	0.003	0.996	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.003	0.996	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.003	0.996	0.000
V40-V49 Car occupant injured in transport accident	0.003	0.996	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.003	0.996	0.000
V01-V09 Pedestrian injured in transport accident	0.003	0.996	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.003	0.997	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.003	0.997	0.000
W21.9 Unspecified place	0.003	0.997	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.003	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.997	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.003	0.997	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.003	0.997	0.000
H74.1 Adhesive middle ear disease	0.003	0.997	0.000
D00-D09 In situ neoplasms	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
M25.51 Pain in joint (Shoulder region)	0.003	0.997	0.000
H93 Other disorders of ear, not elsewhere classified	0.003	0.997	0.000
Z03.4 Observation for suspected myocardial infarction	0.003	0.997	0.000
W29.8 Other specified place	0.003	0.997	0.000
W29.6 Industrial and construction area	0.003	0.997	0.000
W29.0 Home	0.003	0.997	0.000
W29.7 Farm	0.003	0.997	0.000
W29.5 Trade and service area	0.003	0.997	0.000
W29.4 Street and highway	0.003	0.997	0.000
W29.3 Sports and athletics area	0.003	0.997	0.000
W29.2 School, other institution and public administrative area	0.003	0.997	0.000
W29.1 Residential institution	0.003	0.997	0.000
D04 Carcinoma in situ of skin	0.003	0.997	0.000
W25 Contact with sharp glass	0.003	0.997	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.003	0.997	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.003	0.997	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.003	0.997	0.000
W22.8 Other specified place	0.003	0.997	0.000
W22.6 Industrial and construction area	0.003	0.997	0.000
W22.4 Street and highway	0.003	0.997	0.000
W22.0 Home	0.003	0.997	0.000
W22.7 Farm	0.003	0.997	0.000
W22.5 Trade and service area	0.003	0.997	0.000
W22.3 Sports and athletics area	0.003	0.997	0.000
W22.2 School, other institution and public administrative area	0.003	0.997	0.000
W22.1 Residential institution	0.003	0.997	0.000
Y88 Sequelae of surgical and medical care as external cause	0.003	0.997	0.000
W44 Foreign body entering into or through eye or natural orifice	0.003	0.997	0.000
H66.4 Suppurative otitis media, unspecified	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.003	0.997	0.000
H66.0 Acute suppurative otitis media	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
D09 Carcinoma in situ of other and unspecified sites	0.003	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
M25.46 Effusion of joint (Lower leg)	0.003	0.997	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.003	0.997	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.003	0.997	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.003	0.997	0.000
H68.1 Obstruction of Eustachian tube	0.003	0.997	0.000
H68.0 Eustachian salpingitis	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I73.0 Raynaud's syndrome	0.003	0.997	0.000
Y89.9 Sequelae of unspecified external cause	0.003	0.997	0.000
Y65 Other misadventures during surgical and medical care	0.003	0.997	0.000
Y64 Contaminated medical or biological substances	0.003	0.997	0.000
Y63 Failure in dosage during surgical and medical care	0.003	0.997	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.003	0.997	0.000
Y61 Foreign object accidentally left in body during surgical and medical care	0.003	0.997	0.000
Y69 Unspecified misadventure during surgical and medical care	0.003	0.997	0.000
Y66 Nonadministration of surgical and medical care	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.003	0.997	0.000
Chapter VIII Diseases of the ear and mastoid process	0.003	0.997	0.000
D09.0 Bladder	0.003	0.997	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.997	0.003
H90-H95 Other disorders of ear	0.003	0.997	0.000
X62.9 Unspecified place	0.003	0.997	0.000
X84 Intentional self-harm by unspecified means	0.003	0.997	0.000
X83 Intentional self-harm by other specified means	0.003	0.997	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.003	0.997	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.003	0.997	0.000
X80 Intentional self-harm by jumping from a high place	0.003	0.997	0.000
X79 Intentional self-harm by blunt object	0.003	0.997	0.000
X78 Intentional self-harm by sharp object	0.003	0.997	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.003	0.997	0.000
X76 Intentional self-harm by smoke, fire and flames	0.003	0.997	0.000
X75 Intentional self-harm by explosive material	0.003	0.997	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.003	0.997	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.003	0.997	0.000
X72 Intentional self-harm by handgun discharge	0.003	0.997	0.000
X71 Intentional self-harm by drowning and submersion	0.003	0.997	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.003	0.997	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.003	0.997	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.003	0.997	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.003	0.997	0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.003	0.997	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.003	0.997	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations