TreeWAS – Variant ID: rs375244

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
M06.9 Rheumatoid arthritis, unspecified	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	1.000
E03 Other hypothyroidism	0.000	1.000
E20-E35 Disorders of other endocrine glands	0.000	1.000
E27 Other disorders of adrenal gland	0.000	1.000
E27.1 Primary adrenocortical insufficiency	0.001	0.999
L40 Psoriasis	0.003	0.997
E05 Thyrotoxicosis [hyperthyroidism]	0.005	0.995
E10-E14 Diabetes mellitus	0.008	0.992
E10 Insulin-dependent diabetes mellitus	0.008	0.992
M06 Other rheumatoid arthritis	0.009	0.991
E50-E64 Other nutritional deficiencies	0.013	0.987
L40-L45 Papulosquamous disorders	0.014	0.986
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.015	0.985
D86 Sarcoidosis	0.015	0.985
B37 Candidiasis	0.016	0.984
Chapter I Certain infectious and parasitic diseases	0.016	0.984
# Top node	0.017	0.983
B35-B49 Mycoses	0.017	0.983
D86.9 Sarcoidosis, unspecified	0.017	0.983
Chapter XII Diseases of the skin and subcutaneous tissue	0.017	0.983
D80-D89 Certain disorders involving the immune mechanism	0.018	0.982
E05.9 Thyrotoxicosis, unspecified	0.018	0.982
A50-A64 Infections with a predominantly sexual mode of transmission	0.021	0.979
E55 Vitamin D deficiency	0.022	0.978
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.025	0.975
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.025	0.975
B37.0 Candidal stomatitis	0.026	0.974
E10.9 Without complications	0.027	0.973
A63.0 Anogenital (venereal) warts	0.028	0.972
E55.9 Vitamin D deficiency, unspecified	0.029	0.971
B37.8 Candidiasis of other sites	0.038	0.962
D50-D53 Nutritional anaemias	0.039	0.961
M05-M14 Inflammatory polyarthropathies	0.048	0.952
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.049	0.951
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.050	0.950
E10.3 With ophthalmic complications	0.055	0.945
L20-L30 Dermatitis and eczema	0.061	0.939
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.068	0.932
E05.0 Thyrotoxicosis with diffuse goitre	0.070	0.930
D68 Other coagulation defects	0.074	0.926
M06.4 Inflammatory polyarthropathy	0.077	0.923
B25-B34 Other viral diseases	0.085	0.915
E10.1 With ketoacidosis	0.087	0.913
D86.1 Sarcoidosis of lymph nodes	0.092	0.908
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.100	0.900
E27.4 Other and unspecified adrenocortical insufficiency	0.102	0.898
E04 Other non-toxic goitre	0.108	0.892
D50 Iron deficiency anaemia	0.111	0.889
B37.9 Candidiasis, unspecified	0.113	0.887
L40.5 Arthropathic psoriasis	0.117	0.883
D51 Vitamin B12 deficiency anaemia	0.117	0.883
E27.2 Addisonian crisis	0.118	0.882
B25 Cytomegaloviral disease	0.118	0.882
D68.9 Coagulation defect, unspecified	0.118	0.882
B90-B94 Sequelae of infectious and parasitic diseases	0.119	0.881
D50.9 Iron deficiency anaemia, unspecified	0.122	0.878
M05 Seropositive rheumatoid arthritis	0.123	0.877
M07 Psoriatic and enteropathic arthropathies	0.126	0.874
L40.0 Psoriasis vulgaris	0.130	0.870
M06.3 Rheumatoid nodule	0.132	0.868
E10.2 With renal complications	0.133	0.867
E06 Thyroiditis	0.137	0.863
B25.9 Cytomegaloviral disease, unspecified	0.139	0.861
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.144	0.856
L29 Pruritus	0.147	0.853
D68.0 Von Willebrand's disease	0.149	0.851
M31 Other necrotising vasculopathies	0.149	0.851
M20-M25 Other joint disorders	0.150	0.850
E53 Deficiency of other B group vitamins	0.152	0.848
L28 Lichen simplex chronicus and prurigo	0.153	0.847
M35.3 Polymyalgia rheumatica	0.155	0.845
M35 Other systemic involvement of connective tissue	0.156	0.844
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.156	0.844
D86.8 Sarcoidosis of other and combined sites	0.161	0.839
E23 Hypofunction and other disorders of pituitary gland	0.161	0.839
M31.6 Other giant cell arteritis	0.162	0.838
Chapter X Diseases of the respiratory system	0.163	0.837
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.163	0.837
M31.3 Wegener's granulomatosis	0.170	0.830
M05.9 Seropositive rheumatoid arthritis, unspecified	0.176	0.824
E27.8 Other specified disorders of adrenal gland	0.177	0.823
B37.1 Pulmonary candidiasis	0.180	0.820
E10.6 With other specified complications	0.182	0.818
M07.3 Other psoriatic arthropathies	0.182	0.818
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.191	0.809
D86.0 Sarcoidosis of lung	0.194	0.806
J40-J47 Chronic lower respiratory diseases	0.195	0.805
J47 Bronchiectasis	0.196	0.804
D68.5 Primary Thrombophilia	0.197	0.803
E10.0 With coma	0.200	0.800
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.203	0.797
E28 Ovarian dysfunction	0.208	0.792
J20-J22 Other acute lower respiratory infections	0.210	0.790
G35 Multiple sclerosis	0.212	0.788
B35 Dermatophytosis	0.214	0.786
G35-G37 Demyelinating diseases of the central nervous system	0.218	0.782
L10-L14 Bullous disorders	0.219	0.781
E04.0 Non-toxic diffuse goitre	0.219	0.781
Chapter VI Diseases of the nervous system	0.220	0.780
D66 Hereditary factor VIII deficiency	0.222	0.778
L50-L54 Urticaria and erythema	0.224	0.776
D53 Other nutritional anaemias	0.231	0.769
M07.39 Other psoriatic arthropathies (Site unspecified)	0.234	0.766
E20 Hypoparathyroidism	0.236	0.764
D86.3 Sarcoidosis of skin	0.238	0.762
A60 Anogenital herpesviral [herpes simplex] infections	0.238	0.762
L29.2 Pruritus vulvae	0.245	0.755
B91 Sequelae of poliomyelitis	0.246	0.754
G90-G99 Other disorders of the nervous system	0.248	0.752
L40.8 Other psoriasis	0.248	0.752
B50-B64 Protozoal diseases	0.252	0.748
L21 Seborrhoeic dermatitis	0.252	0.747
L28.0 Lichen simplex chronicus	0.254	0.746
E05.8 Other thyrotoxicosis	0.255	0.745
B37.4 Candidiasis of other urogenital sites	0.256	0.744
J44 Other chronic obstructive pulmonary disease	0.258	0.742
E06.3 Autoimmune thyroiditis	0.261	0.739
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.264	0.736
E61 Deficiency of other nutrient elements	0.265	0.735
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.266	0.734
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.269	0.731
M06.37 Rheumatoid nodule (Ankle and foot)	0.271	0.729
G93 Other disorders of brain	0.271	0.729
J80-J84 Other respiratory diseases principally affecting the interstitium	0.271	0.729
B37.7 Candidal septicaemia	0.272	0.728
L29.0 Pruritus ani	0.276	0.724
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.278	0.722
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.279	0.721
M06.32 Rheumatoid nodule (Upper arm)	0.281	0.719
E23.6 Other disorders of pituitary gland	0.282	0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.283	0.717
E03.5 Myxoedema coma	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.283	0.717
E35 Disorders of endocrine glands in diseases classified elsewhere	0.283	0.717
E32 Diseases of thymus	0.283	0.717
E31 Polyglandular dysfunction	0.283	0.717
E30 Disorders of puberty, not elsewhere classified	0.283	0.717
E27.5 Adrenomedullary hyperfunction	0.283	0.717
E27.0 Other adrenocortical overactivity	0.283	0.717
E53.9 Vitamin B deficiency, unspecified	0.284	0.716
G91 Hydrocephalus	0.285	0.715
L40.3 Pustulosis palmaris et plantaris	0.285	0.715
L40.2 Acrodermatitis continua	0.285	0.715
D55-D59 Haemolytic anaemias	0.286	0.714
E04.9 Non-toxic goitre, unspecified	0.286	0.714
E05.5 Thyroid crisis or storm	0.287	0.713
E05.4 Thyrotoxicosis factitia	0.287	0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.287	0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.287	0.713
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.288	0.712
L25 Unspecified contact dermatitis	0.289	0.711
E12 Malnutrition-related diabetes mellitus	0.289	0.711
E10.7 With multiple complications	0.289	0.711
B36 Other superficial mycoses	0.289	0.711
M06.2 Rheumatoid bursitis	0.289	0.711
M06.1 Adult-onset Still's disease	0.289	0.711
L42 Pityriasis rosea	0.292	0.708
E64 Sequelae of malnutrition and other nutritional deficiencies	0.292	0.708
E63 Other nutritional deficiencies	0.292	0.708
E56 Other vitamin deficiencies	0.292	0.708
E50 Vitamin A deficiency	0.292	0.708
E60 Dietary zinc deficiency	0.292	0.708
E59 Dietary selenium deficiency	0.292	0.708
E52 Niacin deficiency [pellagra]	0.292	0.708
J22 Unspecified acute lower respiratory infection	0.292	0.708
G93.3 Postviral fatigue syndrome	0.293	0.707
L44 Other papulosquamous disorders	0.293	0.707
L41 Parapsoriasis	0.293	0.707
L45 Papulosquamous disorders in diseases classified elsewhere	0.293	0.707
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.294	0.706
B37.6 Candidal endocarditis	0.294	0.706
B37.5 Candidal meningitis	0.294	0.706
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.295	0.705
A75-A79 Rickettsioses	0.295	0.705
A70-A74 Other diseases caused by chlamydiae	0.295	0.705
Chapter XVI Certain conditions originating in the perinatal period	0.295	0.705
B48 Other mycoses, not elsewhere classified	0.295	0.705
B47 Mycetoma	0.295	0.705
B46 Zygomycosis	0.295	0.705
B45 Cryptococcosis	0.295	0.705
B43 Chromomycosis and phaeomycotic abscess	0.295	0.705
B42 Sporotrichosis	0.295	0.705
B41 Paracoccidioidomycosis	0.295	0.705
B40 Blastomycosis	0.295	0.705
B39 Histoplasmosis	0.295	0.705
B38 Coccidioidomycosis	0.295	0.705
D82 Immunodeficiency associated with other major defects	0.295	0.704
D81 Combined immunodeficiencies	0.295	0.704
M12 Other specific arthropathies	0.296	0.704
A59 Trichomoniasis	0.298	0.702
A56 Other sexually transmitted chlamydial diseases	0.298	0.702
A54 Gonococcal infection	0.298	0.702
A53 Other and unspecified syphilis	0.298	0.702
A52 Late syphilis	0.298	0.702
A51 Early syphilis	0.298	0.702
A50 Congenital syphilis	0.298	0.702
A64 Unspecified sexually transmitted disease	0.298	0.702
A58 Granuloma inguinale	0.298	0.702
A57 Chancroid	0.298	0.702
A55 Chlamydial lymphogranuloma (venereum)	0.298	0.702
E55.0 Rickets, active	0.299	0.701
L40.1 Generalised pustular psoriasis	0.301	0.699
A63.8 Other specified predominantly sexually transmitted diseases	0.301	0.699
M91-M94 Chondropathies	0.303	0.697
B27 Infectious mononucleosis	0.307	0.693
L28.1 Prurigo nodularis	0.310	0.690
J20 Acute bronchitis	0.315	0.685
L29.8 Other pruritus	0.316	0.684
B35.1 Tinea unguium	0.317	0.683
M09 Juvenile arthritis in diseases classified elsewhere	0.318	0.682
M08 Juvenile arthritis	0.318	0.682
D68.6 Other Thrombophilia	0.318	0.682
D67 Hereditary factor IX deficiency	0.319	0.681
B85-B89 Pediculosis, acariasis and other infestations	0.320	0.680
L27 Dermatitis due to substances taken internally	0.323	0.677
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.324	0.676
L24 Irritant contact dermatitis	0.327	0.673
L26 Exfoliative dermatitis	0.327	0.673
L22 Diaper [napkin] dermatitis	0.327	0.673
E34 Other endocrine disorders	0.327	0.673
E29 Testicular dysfunction	0.327	0.673
E04.2 Non-toxic multinodular goitre	0.328	0.672
E06.9 Thyroiditis, unspecified	0.329	0.670
J81 Pulmonary oedema	0.330	0.670
B44 Aspergillosis	0.331	0.669
E53.8 Deficiency of other specified B group vitamins	0.331	0.669
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.332	0.668
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.333	0.667
A15-A19 Tuberculosis	0.334	0.666
B37.2 Candidiasis of skin and nail	0.334	0.666
E14 Unspecified diabetes mellitus	0.334	0.666
E25 Adrenogenital disorders	0.336	0.664
M06.8 Other specified rheumatoid arthritis	0.337	0.663
M06.48 Inflammatory polyarthropathy (Other)	0.338	0.662
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.338	0.662
M06.46 Inflammatory polyarthropathy (Lower leg)	0.338	0.662
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.338	0.662
M06.44 Inflammatory polyarthropathy (Hand)	0.338	0.662
M06.43 Inflammatory polyarthropathy (Forearm)	0.338	0.662
M06.42 Inflammatory polyarthropathy (Upper arm)	0.338	0.662
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.338	0.662
E51 Thiamine deficiency	0.339	0.661
A65-A69 Other spirochaetal diseases	0.340	0.660
M34 Systemic sclerosis	0.342	0.658
E23.0 Hypopituitarism	0.342	0.658
B33 Other viral diseases, not elsewhere classified	0.344	0.656
B30 Viral conjunctivitis	0.344	0.656
B26 Mumps	0.344	0.656
E26 Hyperaldosteronism	0.346	0.654
G91.9 Hydrocephalus, unspecified	0.346	0.654
J33.0 Polyp of nasal cavity	0.347	0.653
E21.0 Primary hyperparathyroidism	0.349	0.651
J30-J39 Other diseases of upper respiratory tract	0.349	0.651
E10.5 With peripheral circulatory complications	0.351	0.649
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.352	0.648
E28.3 Primary ovarian failure	0.353	0.647
D52 Folate deficiency anaemia	0.353	0.647
J33 Nasal polyp	0.355	0.645
L52 Erythema nodosum	0.356	0.644
G98 Other disorders of nervous system, not elsewhere classified	0.358	0.642
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.358	0.642
L30 Other dermatitis	0.359	0.641
B20-B24 Human immunodeficiency virus [HIV] disease	0.360	0.640
E04.8 Other specified non-toxic goitre	0.360	0.640
B59 Pneumocystosis	0.362	0.638
M35.2 Behcet's disease	0.362	0.638
D50.1 Sideropenic dysphagia	0.363	0.637
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.363	0.636
E27.3 Drug-induced adrenocortical insufficiency	0.367	0.633
M06.0 Seronegative rheumatoid arthritis	0.367	0.633
D51.8 Other vitamin B12 deficiency anaemias	0.367	0.633
D51.2 Transcobalamin II deficiency	0.367	0.633
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.367	0.633
B25.2 Cytomegaloviral pancreatitis	0.367	0.632
B25.1 Cytomegaloviral hepatitis	0.367	0.632
B25.0 Cytomegaloviral pneumonitis	0.367	0.632
G93.9 Disorder of brain, unspecified	0.368	0.632
B94.8 Sequelae of other specified infectious and parasitic diseases	0.368	0.632
B90 Sequelae of tuberculosis	0.368	0.632
B92 Sequelae of leprosy	0.368	0.632
E27.9 Disorder of adrenal gland, unspecified	0.369	0.631
D53.9 Nutritional anaemia, unspecified	0.369	0.631
G94 Other disorders of brain in diseases classified elsewhere	0.370	0.630
M30 Polyarteritis nodosa and related conditions	0.370	0.630
L23 Allergic contact dermatitis	0.371	0.629
M05.8 Other seropositive rheumatoid arthritis	0.371	0.629
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.371	0.629
M05.2 Rheumatoid vasculitis	0.371	0.629
M05.1 Rheumatoid lung disease	0.371	0.629
M05.0 Felty's syndrome	0.371	0.629
J39 Other diseases of upper respiratory tract	0.373	0.627
M60-M63 Disorders of muscles	0.373	0.627
M07.6 Other enteropathic arthropathies	0.374	0.626
M07.5 Arthropathy in ulcerative colitis	0.374	0.626
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.374	0.626
M07.2 Psoriatic spondylitis	0.374	0.626
M07.1 Arthritis mutilans	0.374	0.626
M07.0 Distal interphalangeal psoriatic arthropathy	0.374	0.626
G93.0 Cerebral cysts	0.374	0.626
M31.0 Hypersensitivity angiitis	0.375	0.625
L40.4 Guttate psoriasis	0.376	0.623
M06.39 Rheumatoid nodule (Site unspecified)	0.377	0.623
M06.38 Rheumatoid nodule (Other)	0.377	0.623
M06.36 Rheumatoid nodule (Lower leg)	0.377	0.623
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.377	0.623
M06.33 Rheumatoid nodule (Forearm)	0.377	0.623
M06.31 Rheumatoid nodule (Shoulder region)	0.377	0.623
M06.30 Rheumatoid nodule (Multiple sites)	0.377	0.623
M93 Other osteochondropathies	0.378	0.621
G91.1 Obstructive hydrocephalus	0.379	0.621
M32 Systemic lupus erythematosus	0.379	0.621
B99-B99 Other infectious diseases	0.380	0.620
L51 Erythema multiforme	0.380	0.620
E06.5 Other chronic thyroiditis	0.381	0.619
E06.4 Drug-induced thyroiditis	0.381	0.619
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.381	0.619
E06.1 Subacute thyroiditis	0.381	0.619
E06.0 Acute thyroiditis	0.381	0.619
M07.30 Other psoriatic arthropathies (Multiple sites)	0.383	0.617
D68.4 Acquired coagulation factor deficiency	0.383	0.617
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.383	0.616
M10 Gout	0.385	0.615
B25.8 Other cytomegaloviral diseases	0.386	0.614
L13 Other bullous disorders	0.387	0.613
A80-A89 Viral infections of the central nervous system	0.388	0.612
M06.34 Rheumatoid nodule (Hand)	0.388	0.612
L29.3 Anogenital pruritus, unspecified	0.388	0.612
L29.1 Pruritus scroti	0.388	0.612
M35.1 Other overlap syndromes	0.389	0.611
A20-A28 Certain zoonotic bacterial diseases	0.389	0.611
E54 Ascorbic acid deficiency	0.389	0.610
L21.9 Seborrhoeic dermatitis, unspecified	0.390	0.610
M31.8 Other specified necrotising vasculopathies	0.390	0.610
M31.7 Microscopic polyangiitis	0.390	0.610
M31.4 Aortic arch syndrome [Takayasu]	0.390	0.610
M31.2 Lethal midline granuloma	0.390	0.610
M31.1 Thrombotic microangiopathy	0.390	0.610
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.391	0.609
E53.1 Pyridoxine deficiency	0.392	0.608
E53.0 Riboflavin deficiency	0.392	0.608
L28.2 Other prurigo	0.393	0.607
E04.1 Non-toxic single thyroid nodule	0.393	0.607
E23.2 Diabetes insipidus	0.393	0.607
E03.8 Other specified hypothyroidism	0.394	0.606
A60.0 Herpesviral infection of genitalia and urogenital tract	0.394	0.606
M35.9 Systemic involvement of connective tissue, unspecified	0.394	0.605
M35.6 Relapsing panniculitis [Weber-Christian]	0.394	0.605
M35.5 Multifocal fibrosclerosis	0.394	0.605
M35.4 Diffuse (eosinophilic) fasciitis	0.394	0.605
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.395	0.605
L12 Pemphigoid	0.397	0.603
D68.1 Hereditary factor XI deficiency	0.397	0.603
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.399	0.601
E23.1 Drug-induced hypopituitarism	0.399	0.601
M07.36 Other psoriatic arthropathies (Lower leg)	0.400	0.600
J39.8 Other specified diseases of upper respiratory tract	0.401	0.599
M95.0 Acquired deformity of nose	0.402	0.598
E58 Dietary calcium deficiency	0.403	0.596
J44.8 Other specified chronic obstructive pulmonary disease	0.404	0.596
E20.9 Hypoparathyroidism, unspecified	0.405	0.595
J21 Acute bronchiolitis	0.405	0.595
M06.98 Rheumatoid arthritis, unspecified (Other)	0.409	0.591
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.409	0.591
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.409	0.591
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.409	0.591
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.409	0.591
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.409	0.591
D83 Common variable immunodeficiency	0.409	0.590
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.409	0.590
L20 Atopic dermatitis	0.410	0.590
J20.9 Acute bronchitis, unspecified	0.410	0.590
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.412	0.588
M07.38 Other psoriatic arthropathies (Other)	0.413	0.586
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.413	0.586
M07.33 Other psoriatic arthropathies (Forearm)	0.413	0.586
M07.32 Other psoriatic arthropathies (Upper arm)	0.413	0.586
M07.31 Other psoriatic arthropathies (Shoulder region)	0.413	0.586
E61.1 Iron deficiency	0.415	0.585
E22 Hyperfunction of pituitary gland	0.417	0.583
L50 Urticaria	0.419	0.581
B95-B98 Bacterial, viral and other infectious agents	0.420	0.580
E14.3 With ophthalmic complications	0.421	0.579
E24 Cushing's syndrome	0.424	0.576
D84 Other immunodeficiencies	0.426	0.574
E28.9 Ovarian dysfunction, unspecified	0.432	0.568
E28.8 Other ovarian dysfunction	0.432	0.568
E28.1 Androgen excess	0.432	0.568
E28.0 Oestrogen excess	0.432	0.568
B97 Viral agents as the cause of diseases classified to other chapters	0.432	0.568
M93.9 Osteochondropathy, unspecified	0.432	0.568
B65-B83 Helminthiases	0.435	0.565
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.436	0.564
B35.9 Dermatophytosis, unspecified	0.436	0.564
B35.8 Other dermatophytoses	0.436	0.564
B35.6 Tinea cruris	0.436	0.564
B35.5 Tinea imbricata	0.436	0.564
B35.4 Tinea corporis	0.436	0.564
B35.2 Tinea manuum	0.436	0.564
B35.0 Tinea barbae and tinea capitis	0.436	0.564
E28.2 Polycystic ovarian syndrome	0.436	0.564
G91.8 Other hydrocephalus	0.438	0.562
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.439	0.561
L10 Pemphigus	0.440	0.560
L14 Bullous disorders in diseases classified elsewhere	0.440	0.560
L54 Erythema in diseases classified elsewhere	0.443	0.557
J80 Adult respiratory distress syndrome	0.445	0.555
E10.8 With unspecified complications	0.448	0.551
D53.8 Other specified nutritional anaemias	0.449	0.551
D53.2 Scorbutic anaemia	0.449	0.551
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.449	0.551
D53.0 Protein deficiency anaemia	0.449	0.551
M35.0 Sicca syndrome [Sjogren]	0.449	0.551
L25.9 Unspecified contact dermatitis, unspecified cause	0.452	0.548
E20.8 Other hypoparathyroidism	0.452	0.548
E20.1 Pseudohypoparathyroidism	0.452	0.548
E20.0 Idiopathic hypoparathyroidism	0.452	0.548
L11 Other acantholytic disorders	0.454	0.546
A60.9 Anogenital herpesviral infection, unspecified	0.454	0.546
A60.1 Herpesviral infection of perianal skin and rectum	0.454	0.546
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.454	0.546
L30.9 Dermatitis, unspecified	0.456	0.544
G93.5 Compression of brain	0.457	0.543
M35.8 Other specified systemic involvement of connective tissue	0.459	0.540
G91.0 Communicating hydrocephalus	0.460	0.540
G37 Other demyelinating diseases of central nervous system	0.460	0.540
G92 Toxic encephalopathy	0.461	0.539
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.461	0.539
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.462	0.538
J41 Simple and mucopurulent chronic bronchitis	0.462	0.538
B60 Other protozoal diseases, not elsewhere classified	0.463	0.536
B58 Toxoplasmosis	0.463	0.536
B57 Chagas' disease	0.463	0.536
B56 African trypanosomiasis	0.463	0.536
B55 Leishmaniasis	0.463	0.536
B53 Other parasitologically confirmed malaria	0.463	0.536
B52 Plasmodium malariae malaria	0.463	0.536
B51 Plasmodium vivax malaria	0.463	0.536
B64 Unspecified protozoal disease	0.463	0.536
L21.8 Other seborrhoeic dermatitis	0.464	0.536
L21.1 Seborrhoeic infantile dermatitis	0.464	0.536
L21.0 Seborrhoea capitis	0.464	0.536
B27.9 Infectious mononucleosis, unspecified	0.465	0.534
E23.7 Disorder of pituitary gland, unspecified	0.467	0.533
M35.7 Hypermobility syndrome	0.467	0.533
J95-J99 Other diseases of the respiratory system	0.468	0.532
J20.8 Acute bronchitis due to other specified organisms	0.470	0.530
J34 Other disorders of nose and nasal sinuses	0.470	0.530
M91 Juvenile osteochondrosis of hip and pelvis	0.471	0.529
D56 Thalassaemia	0.471	0.529
E34.0 Carcinoid syndrome	0.471	0.529
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.471	0.528
D69 Purpura and other haemorrhagic conditions	0.472	0.528
B94.9 Sequelae of unspecified infectious or parasitic disease	0.472	0.528
B94.2 Sequelae of viral hepatitis	0.472	0.528
B94.1 Sequelae of viral encephalitis	0.472	0.528
B94.0 Sequelae of trachoma	0.472	0.528
G36 Other acute disseminated demyelination	0.472	0.527
G93.6 Cerebral oedema	0.473	0.527
E61.9 Deficiency of nutrient element, unspecified	0.473	0.527
E61.8 Deficiency of other specified nutrient elements	0.473	0.527
E61.7 Deficiency of multiple nutrient elements	0.473	0.527
E61.6 Vanadium deficiency	0.473	0.527
E61.5 Molybdenum deficiency	0.473	0.527
E61.4 Chromium deficiency	0.473	0.527
E61.3 Manganese deficiency	0.473	0.527
E61.0 Copper deficiency	0.473	0.527
M12.2 Villonodular synovitis (pigmented)	0.473	0.527
J39.0 Retropharyngeal and parapharyngeal abscess	0.473	0.527
E10.4 With neurological complications	0.474	0.526
G94.2 Hydrocephalus in other diseases classified elsewhere	0.476	0.524
G93.7 Reye's syndrome	0.477	0.522
M07.34 Other psoriatic arthropathies (Hand)	0.478	0.522
D59 Acquired haemolytic anaemia	0.478	0.522
M14 Arthropathies in other diseases classified elsewhere	0.478	0.522
M10.0 Idiopathic gout	0.479	0.521
M34.8 Other forms of systemic sclerosis	0.480	0.520
J46 Status asthmaticus	0.481	0.519
M33 Dermatopolymyositis	0.481	0.518
J34.3 Hypertrophy of nasal turbinates	0.482	0.518
M11 Other crystal arthropathies	0.483	0.517
E21.4 Other specified disorders of parathyroid gland	0.483	0.517
E21.2 Other hyperparathyroidism	0.483	0.517
E40-E46 Malnutrition	0.483	0.516
J39.9 Disease of upper respiratory tract, unspecified	0.484	0.516
B36.9 Superficial mycosis, unspecified	0.484	0.516
D51.3 Other dietary vitamin B12 deficiency anaemia	0.484	0.515
G93.1 Anoxic brain damage, not elsewhere classified	0.485	0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.486	0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations