TreeWAS – Variant ID: rs3758354

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
S00-S09 Injuries to the head	0.105	0.895
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.104	0.896
T36-T50 Poisoning by drugs, medicaments and biological substances	0.101	0.899
S01 Open wound of head	0.100	0.900
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.099	0.901
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.095	0.905
S90-S99 Injuries to the ankle and foot	0.094	0.906
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.090	0.910
S02 Fracture of skull and facial bones	0.089	0.911
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.089	0.911
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.087	0.913
S01.5 Open wound of lip and oral cavity	0.087	0.913
S30 Superficial injury of abdomen, lower back and pelvis	0.087	0.913
S20-S29 Injuries to the thorax	0.087	0.913
S01.8 Open wound of other parts of head	0.087	0.913
S31 Open wound of abdomen, lower back and pelvis	0.086	0.914
S01.2 Open wound of nose	0.084	0.916
S09 Other and unspecified injuries of head	0.084	0.916
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.084	0.916
S32 Fracture of lumbar spine and pelvis	0.083	0.917
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.083	0.917
S50-S59 Injuries to the elbow and forearm	0.082	0.918
S05 Injury of eye and orbit	0.082	0.918
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.081	0.918
S02.6 Fracture of mandible	0.081	0.919
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.081	0.919
S10-S19 Injuries to the neck	0.081	0.919
S90 Superficial injury of ankle and foot	0.081	0.919
S06 Intracranial injury	0.080	0.920
S00 Superficial injury of head	0.080	0.920
T86 Failure and rejection of transplanted organs and tissues	0.080	0.920
T84.2 Mechanical complication of internal fixation device of other bones	0.080	0.920
S22 Fracture of rib(s), sternum and thoracic spine	0.079	0.921
T40.2 Other opioids	0.079	0.921
S01.7 Multiple open wounds of head	0.079	0.921
T93 Sequelae of injuries of lower limb	0.079	0.921
T43.5 Other and unspecified antipsychotics and neuroleptics	0.078	0.922
T84.3 Mechanical complication of other bone devices, implants and grafts	0.078	0.922
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.078	0.922
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.077	0.923
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.077	0.923
T87 Complications peculiar to reattachment and amputation	0.077	0.923
S30.0 Contusion of lower back and pelvis	0.076	0.924
S02.60 Fracture of mandible (closed)	0.076	0.924
S08 Traumatic amputation of part of head	0.076	0.924
S07 Crushing injury of head	0.076	0.924
S04 Injury of cranial nerves	0.076	0.924
S03 Dislocation, sprain and strain of joints and ligaments of head	0.076	0.924
S01.1 Open wound of eyelid and periocular area	0.076	0.924
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.075	0.925
T33-T35 Frostbite	0.075	0.925
T26-T28 Burns and corrosions confined to eye and internal organs	0.075	0.925
T20-T25 Burns and corrosions of external body surface, specified by site	0.075	0.925
T00-T07 Injuries involving multiple body regions	0.075	0.925
S91 Open wound of ankle and foot	0.075	0.925
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.074	0.925
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.074	0.926
S32.7 Multiple fractures of lumbar spine and pelvis	0.074	0.926
S22.0 Fracture of thoracic vertebra	0.073	0.927
S92 Fracture of foot, except ankle	0.073	0.927
T80 Complications following infusion, transfusion and therapeutic injection	0.073	0.927
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.072	0.928
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.072	0.928
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.072	0.928
T46 Poisoning by agents primarily affecting the cardiovascular system	0.072	0.928
T41 Poisoning by anaesthetics and therapeutic gases	0.072	0.928
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.072	0.928
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.072	0.928
T36 Poisoning by systemic antibiotics	0.072	0.928
T42.4 Benzodiazepines	0.072	0.928
T83.1 Mechanical complication of other urinary devices and implants	0.072	0.928
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.072	0.928
S60-S69 Injuries to the wrist and hand	0.072	0.928
T79-T79 Certain early complications of trauma	0.072	0.928
S31.1 Open wound of abdominal wall	0.072	0.928
S02.1 Fracture of base of skull	0.072	0.928
S01.4 Open wound of cheek and temporomandibular area	0.072	0.928
S30.1 Contusion of abdominal wall	0.071	0.929
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.071	0.929
S37 Injury of urinary and pelvic organs	0.071	0.929
S36 Injury of intra-abdominal organs	0.071	0.929
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.071	0.929
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.071	0.929
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.071	0.929
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.071	0.929
T91 Sequelae of injuries of neck and trunk	0.071	0.929
S01.0 Open wound of scalp	0.071	0.929
S99 Other and unspecified injuries of ankle and foot	0.070	0.929
S31.0 Open wound of lower back and pelvis	0.069	0.931
T93.2 Sequelae of other fractures of lower limb	0.069	0.931
S09.9 Unspecified injury of head	0.068	0.931
S22.00 Fracture of thoracic vertebra (closed)	0.068	0.932
S02.9 Fracture of skull and facial bones, part unspecified	0.068	0.932
S98 Traumatic amputation of ankle and foot	0.068	0.932
S97 Crushing injury of ankle and foot	0.068	0.932
S96 Injury of muscle and tendon at ankle and foot level	0.068	0.932
S95 Injury of blood vessels at ankle and foot level	0.068	0.932
S94 Injury of nerves at ankle and foot level	0.068	0.932
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.068	0.932
T98 Sequelae of other and unspecified effects of external causes	0.068	0.932
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.068	0.932
T45.0 Antiallergic and antiemetic drugs	0.068	0.932
S90.9 Superficial injury of ankle and foot, unspecified	0.068	0.932
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.067	0.933
S59 Other and unspecified injuries of forearm	0.067	0.933
T94 Sequelae of injuries involving multiple and unspecified body regions	0.067	0.933
S01.9 Open wound of head, part unspecified	0.066	0.934
S02.3 Fracture of orbital floor	0.066	0.934
T43.0 Tricyclic and tetracyclic antidepressants	0.066	0.934
S32.4 Fracture of acetabulum	0.065	0.935
S00.3 Superficial injury of nose	0.065	0.935
S06.2 Diffuse brain injury	0.065	0.935
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.065	0.935
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.065	0.935
T95 Sequelae of burns, corrosions and frostbite	0.065	0.935
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.065	0.935
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.065	0.935
S22.3 Fracture of rib	0.065	0.935
S05.9 Injury of eye and orbit, part unspecified	0.065	0.935
S05.8 Other injuries of eye and orbit	0.064	0.936
S02.7 Multiple fractures involving skull and facial bones	0.064	0.936
S02.0 Fracture of vault of skull	0.064	0.936
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.064	0.936
S00.9 Superficial injury of head, part unspecified	0.064	0.936
S50 Superficial injury of forearm	0.064	0.936
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.064	0.936
T86.1 Kidney transplant failure and rejection	0.063	0.936
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.063	0.937
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.063	0.937
S51 Open wound of forearm	0.063	0.937
S90.8 Other superficial injuries of ankle and foot	0.063	0.937
S01.3 Open wound of ear	0.063	0.937
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.063	0.937
T88 Other complications of surgical and medical care, not elsewhere classified	0.063	0.937
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.063	0.937
T40.8 Lysergide [LSD]	0.063	0.937
T40.7 Cannabis (derivatives)	0.063	0.937
T40.6 Other and unspecified narcotics	0.063	0.937
T40.5 Cocaine	0.063	0.937
T40.3 Methadone	0.063	0.937
T40.1 Heroin	0.063	0.937
T40.0 Opium	0.063	0.937
T83.3 Mechanical complication of intra-uterine contraceptive device	0.063	0.937
T39.0 Salicylates	0.063	0.937
T86.8 Failure and rejection of other transplanted organs and tissues	0.063	0.937
S27 Injury of other and unspecified intrathoracic organs	0.063	0.937
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.062	0.937
S30.2 Contusion of external genital organs	0.062	0.937
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.062	0.937
S26 Injury of heart	0.062	0.937
S25 Injury of blood vessels of thorax	0.062	0.937
S24 Injury of nerves and spinal cord at thorax level	0.062	0.937
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.062	0.937
S21 Open wound of thorax	0.062	0.937
T93.9 Sequelae of unspecified injury of lower limb	0.062	0.938
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.062	0.938
T92 Sequelae of injuries of upper limb	0.062	0.938
S31.8 Open wound of other and unspecified parts of abdomen	0.062	0.938
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.062	0.938
S31.5 Open wound of other and unspecified external genital organs	0.062	0.938
S31.4 Open wound of vagina and vulva	0.062	0.938
S31.3 Open wound of scrotum and testes	0.062	0.938
S31.2 Open wound of penis	0.062	0.938
T87.4 Infection of amputation stump	0.061	0.939
S32.1 Fracture of sacrum	0.061	0.939
T40.4 Other synthetic narcotics	0.061	0.939
S00.7 Multiple superficial injuries of head	0.061	0.939
S00.2 Other superficial injuries of eyelid and periocular area	0.061	0.939
T90 Sequelae of injuries of head	0.061	0.939
S09.8 Other specified injuries of head	0.060	0.940
S09.7 Multiple injuries of head	0.060	0.940
S09.2 Traumatic rupture of ear drum	0.060	0.940
S09.1 Injury of muscle and tendon of head	0.060	0.940
S09.0 Injury of blood vessels of head, not elsewhere classified	0.060	0.940
T86.0 Bone-marrow transplant rejection	0.060	0.940
T43.9 Psychotropic drug, unspecified	0.060	0.940
T43.8 Other psychotropic drugs, not elsewhere classified	0.060	0.940
T43.6 Psychostimulants with abuse potential	0.060	0.940
T43.4 Butyrophenone and thioxanthene neuroleptics	0.060	0.940
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.060	0.940
S02.8 Fractures of other skull and facial bones	0.060	0.940
S32.3 Fracture of ilium	0.060	0.940
S32.2 Fracture of coccyx	0.060	0.940
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.060	0.940
T15-T19 Effects of foreign body entering through natural orifice	0.059	0.940
S22.4 Multiple fractures of ribs	0.060	0.940
S91.1 Open wound of toe(s) without damage to nail	0.060	0.940
S02.10 Fracture of base of skull (closed)	0.060	0.940
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.059	0.940
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.059	0.940
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.059	0.940
T83.2 Mechanical complication of graft of urinary organ	0.059	0.940
S58 Traumatic amputation of forearm	0.059	0.941
S57 Crushing injury of forearm	0.059	0.941
S56 Injury of muscle and tendon at forearm level	0.059	0.941
S55 Injury of blood vessels at forearm level	0.059	0.941
S54 Injury of nerves at forearm level	0.059	0.941
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.059	0.941
S06.3 Focal brain injury	0.059	0.941
S92.4 Fracture of great toe	0.059	0.941
S05.7 Avulsion of eye	0.059	0.941
S05.6 Penetrating wound of eyeball without foreign body	0.059	0.941
S05.5 Penetrating wound of eyeball with foreign body	0.059	0.941
S05.4 Penetrating wound of orbit with or without foreign body	0.059	0.941
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.059	0.941
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.059	0.941
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.059	0.941
S29 Other and unspecified injuries of thorax	0.059	0.941
T45.9 Primarily systemic and haematological agent, unspecified	0.059	0.941
T45.8 Other primarily systemic and haematological agents	0.059	0.941
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.059	0.941
T45.6 Fibrinolysis-affecting drugs	0.059	0.941
T45.5 Anticoagulants	0.059	0.941
T45.4 Iron and its compounds	0.059	0.941
T45.3 Enzymes, not elsewhere classified	0.059	0.941
T45.2 Vitamins, not elsewhere classified	0.059	0.941
T45.1 Antineoplastic and immunosuppressive drugs	0.059	0.941
T87.6 Other and unspecified complications of amputation stump	0.059	0.941
S62 Fracture at wrist and hand level	0.059	0.941
S02.61 Fracture of mandible (open)	0.058	0.941
S19 Other and unspecified injuries of neck	0.058	0.941
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.058	0.942
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.058	0.942
T42.5 Mixed antiepileptics, not elsewhere classified	0.058	0.942
T42.3 Barbiturates	0.058	0.942
T42.2 Succinimides and oxazolidinediones	0.058	0.942
T42.1 Iminostilbenes	0.058	0.942
T42.0 Hydantoin derivatives	0.058	0.942
S17 Crushing injury of neck	0.058	0.942
S15 Injury of blood vessels at neck level	0.058	0.942
S14 Injury of nerves and spinal cord at neck level	0.058	0.942
S11 Open wound of neck	0.058	0.942
S10 Superficial injury of neck	0.058	0.942
S18 Traumatic amputation at neck level	0.058	0.942
S16 Injury of muscle and tendon at neck level	0.058	0.942
S90.7 Multiple superficial injuries of ankle and foot	0.058	0.942
S90.3 Contusion of other and unspecified parts of foot	0.058	0.942
S90.2 Contusion of toe(s) with damage to nail	0.058	0.942
S90.1 Contusion of toe(s) without damage to nail	0.058	0.942
S90.0 Contusion of ankle	0.058	0.942
S06.6 Traumatic subarachnoid haemorrhage	0.058	0.942
S40-S49 Injuries to the shoulder and upper arm	0.058	0.942
S06.9 Intracranial injury, unspecified	0.058	0.942
S06.8 Other intracranial injuries	0.058	0.942
S06.7 Intracranial injury with prolonged coma	0.058	0.942
S06.4 Epidural haemorrhage	0.058	0.942
S06.1 Traumatic cerebral oedema	0.058	0.942
S00.5 Superficial injury of lip and oral cavity	0.058	0.942
S00.4 Superficial injury of ear	0.058	0.942
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.057	0.942
T86.4 Liver transplant failure and rejection	0.057	0.942
T86.3 Heart-lung transplant failure and rejection	0.057	0.942
T86.2 Heart transplant failure and rejection	0.057	0.942
S02.2 Fracture of nasal bones	0.057	0.943
T83.0 Mechanical complication of urinary (indwelling) catheter	0.057	0.943
S12 Fracture of neck	0.057	0.943
S22.9 Fracture of bony thorax, part unspecified	0.057	0.943
S22.8 Fracture of other parts of bony thorax	0.057	0.943
S22.5 Flail chest	0.057	0.943
S22.1 Multiple fractures of thoracic spine	0.057	0.943
S60 Superficial injury of wrist and hand	0.057	0.943
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.057	0.943
S64 Injury of nerves at wrist and hand level	0.057	0.943
S59.9 Unspecified injury of forearm	0.057	0.943
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.056	0.943
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.056	0.943
T93.4 Sequelae of injury of nerve of lower limb	0.056	0.943
T93.1 Sequelae of fracture of femur	0.056	0.943
T93.0 Sequelae of open wound of lower limb	0.056	0.943
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.056	0.944
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.056	0.944
T39.4 Antirheumatics, not elsewhere classified	0.056	0.944
T39.2 Pyrazolone derivatives	0.056	0.944
S02.5 Fracture of tooth	0.056	0.944
S06.5 Traumatic subdural haemorrhage	0.056	0.944
T84.1 Mechanical complication of internal fixation device of bones of limb	0.056	0.944
S91.3 Open wound of other parts of foot	0.056	0.944
S02.4 Fracture of malar and maxillary bones	0.056	0.944
T43.3 Phenothiazine antipsychotics and neuroleptics	0.056	0.944
T91.1 Sequelae of fracture of spine	0.056	0.944
T85 Complications of other internal prosthetic devices, implants and grafts	0.056	0.944
S32.5 Fracture of pubis	0.055	0.944
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.055	0.944
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.055	0.944
T87.5 Necrosis of amputation stump	0.055	0.945
T87.3 Neuroma of amputation stump	0.055	0.945
T87.2 Complications of other reattached body part	0.055	0.945
T87.1 Complications of reattached (part of) lower extremity	0.055	0.945
T87.0 Complications of reattached (part of) upper extremity	0.055	0.945
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.055	0.945
T50.9 Other and unspecified drugs, medicaments and biological substances	0.055	0.945
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.055	0.945
S05.1 Contusion of eyeball and orbital tissues	0.055	0.945
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.054	0.945
S03.4 Sprain and strain of jaw	0.054	0.945
S03.3 Dislocation of other and unspecified parts of head	0.054	0.945
S03.2 Dislocation of tooth	0.054	0.945
S03.1 Dislocation of septal cartilage of nose	0.054	0.945
S03.0 Dislocation of jaw	0.054	0.945
S04.9 Injury of unspecified cranial nerve	0.054	0.945
S04.8 Injury of other cranial nerves	0.054	0.945
S04.7 Injury of accessory nerve	0.054	0.945
S04.6 Injury of acoustic nerve	0.054	0.945
S04.5 Injury of facial nerve	0.054	0.945
S04.4 Injury of abducent nerve	0.054	0.945
S04.3 Injury of trigeminal nerve	0.054	0.945
S04.2 Injury of trochlear nerve	0.054	0.945
S04.1 Injury of oculomotor nerve	0.054	0.945
S04.0 Injury of optic nerve and pathways	0.054	0.945
S07.9 Crushing injury of head, part unspecified	0.054	0.945
S07.8 Crushing injury of other parts of head	0.054	0.945
S07.1 Crushing injury of skull	0.054	0.945
S07.0 Crushing injury of face	0.054	0.945
S08.9 Traumatic amputation of unspecified part of head	0.054	0.945
S08.8 Traumatic amputation of other parts of head	0.054	0.945
S08.1 Traumatic amputation of ear	0.054	0.945
S08.0 Avulsion of scalp	0.054	0.945
S06.20 Diffuse brain injury (without open intracranial wound)	0.054	0.946
S00.1 Contusion of eyelid and periocular area	0.054	0.946
S22.30 Fracture of rib (closed)	0.054	0.946
T06 Other injuries involving multiple body regions, not elsewhere classified	0.054	0.946
T05 Traumatic amputations involving multiple body regions	0.054	0.946
T04 Crushing injuries involving multiple body regions	0.054	0.946
T03 Dislocations, sprains and strains involving multiple body regions	0.054	0.946
T02 Fractures involving multiple body regions	0.054	0.946
T01 Open wounds involving multiple body regions	0.054	0.946
T00 Superficial injuries involving multiple body regions	0.054	0.946
T07 Unspecified multiple injuries	0.054	0.946
T25 Burn and corrosion of ankle and foot	0.054	0.946
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.054	0.946
T23 Burn and corrosion of wrist and hand	0.054	0.946
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.054	0.946
T21 Burn and corrosion of trunk	0.054	0.946
T20 Burn and corrosion of head and neck	0.054	0.946
T28 Burn and corrosion of other internal organs	0.054	0.946
T27 Burn and corrosion of respiratory tract	0.054	0.946
T26 Burn and corrosion confined to eye and adnexa	0.054	0.946
T35 Frostbite involving multiple body regions and unspecified frostbite	0.054	0.946
T34 Frostbite with tissue necrosis	0.054	0.946
T33 Superficial frostbite	0.054	0.946
T93.8 Sequelae of other specified injuries of lower limb	0.054	0.946
S91.7 Multiple open wounds of ankle and foot	0.054	0.946
S91.2 Open wound of toe(s) with damage to nail	0.054	0.946
S91.0 Open wound of ankle	0.054	0.946
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.054	0.946
S06.0 Concussion	0.053	0.946
T13 Other injuries of lower limb, level unspecified	0.053	0.946
T11 Other injuries of upper limb, level unspecified	0.053	0.946
T09 Other injuries of spine and trunk, level unspecified	0.053	0.946
T12.X1 Fracture of lower limb, level unspecified (open)	0.053	0.946
T12.X0 Fracture of lower limb, level unspecified (closed)	0.053	0.946
T12 Fracture of lower limb, level unspecified	0.053	0.946
T10.X1 Fracture of upper limb, level unspecified (open)	0.053	0.946
T10.X0 Fracture of upper limb, level unspecified (closed)	0.053	0.946
T10 Fracture of upper limb, level unspecified	0.053	0.946
T08.X1 Fracture of spine, level unspecified (open)	0.053	0.946
T08.X0 Fracture of spine, level unspecified (closed)	0.053	0.946
T08 Fracture of spine, level unspecified	0.053	0.946
S99.9 Unspecified injury of ankle and foot	0.053	0.946
T50.8 Diagnostic agents	0.053	0.947
T50.7 Analeptics and opioid receptor antagonists	0.053	0.947
T50.6 Antidotes and chelating agents, not elsewhere classified	0.053	0.947
T50.5 Appetite depressants	0.053	0.947
T50.4 Drugs affecting uric acid metabolism	0.053	0.947
T50.3 Electrolytic, caloric and water-balance agents	0.053	0.947
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.053	0.947
T50.1 Loop [high-ceiling] diuretics	0.053	0.947
T50.0 Mineralocorticoids and their antagonists	0.053	0.947
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.053	0.947
S69 Other and unspecified injuries of wrist and hand	0.053	0.947
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.053	0.947
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.053	0.947
T14 Injury of unspecified body region	0.053	0.947
T66-T78 Other and unspecified effects of external causes	0.053	0.947
S20 Superficial injury of thorax	0.053	0.947
T91.8 Sequelae of other specified injuries of neck and trunk	0.052	0.947
S22.01 Fracture of thoracic vertebra (open)	0.052	0.947
S92.9 Fracture of foot, unspecified	0.052	0.948
S92.7 Multiple fractures of foot	0.052	0.948
S92.5 Fracture of other toe	0.052	0.948
S92.2 Fracture of other tarsal bone(s)	0.052	0.948
S92.1 Fracture of talus	0.052	0.948
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.052	0.948
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.052	0.948
T80.6 Other serum reactions	0.052	0.948
T80.5 Anaphylactic shock due to serum	0.052	0.948
T80.4 Rh incompatibility reaction	0.052	0.948
T80.3 ABO incompatibility reaction	0.052	0.948
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.052	0.948
S32.40 Fracture of acetabulum (closed)	0.052	0.948
T80.2 Infections following infusion, transfusion and therapeutic injection	0.052	0.948
T36.9 Systemic antibiotic, unspecified	0.052	0.948
T36.8 Other systemic antibiotics	0.052	0.948
T36.7 Antifungal antibiotics, systemically used	0.052	0.948
T36.6 Rifamycins	0.052	0.948
T36.5 Aminoglycosides	0.052	0.948
T36.4 Tetracyclines	0.052	0.948
T36.3 Macrolides	0.052	0.948
T36.2 Chloramphenicol group	0.052	0.948
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.052	0.948
T36.0 Penicillins	0.052	0.948
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.052	0.948
T37.8 Other specified systemic anti-infectives and antiparasitics	0.052	0.948
T37.5 Antiviral drugs	0.052	0.948
T37.4 Anthelminthics	0.052	0.948
T37.3 Other antiprotozoal drugs	0.052	0.948
T37.2 Antimalarials and drugs acting on other blood protozoa	0.052	0.948
T37.1 Antimycobacterial drugs	0.052	0.948
T37.0 Sulphonamides	0.052	0.948
T38.9 Other and unspecified hormone antagonists	0.052	0.948
T38.8 Other and unspecified hormones and their synthetic substitutes	0.052	0.948
T38.7 Androgens and anabolic congeners	0.052	0.948
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.052	0.948
T38.5 Other oestrogens and progestogens	0.052	0.948
T38.4 Oral contraceptives	0.052	0.948
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.052	0.948
T38.2 Antithyroid drugs	0.052	0.948
T38.1 Thyroid hormones and substitutes	0.052	0.948
T38.0 Glucocorticoids and synthetic analogues	0.052	0.948
T41.5 Therapeutic gases	0.052	0.948
T41.4 Anaesthetic, unspecified	0.052	0.948
T41.3 Local anaesthetics	0.052	0.948
T41.2 Other and unspecified general anaesthetics	0.052	0.948
T41.1 Intravenous anaesthetics	0.052	0.948
T41.0 Inhaled anaesthetics	0.052	0.948
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.052	0.948
T46.8 Antivaricose drugs, including sclerosing agents	0.052	0.948
T46.7 Peripheral vasodilators	0.052	0.948
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.052	0.948
T46.5 Other antihypertensive drugs, not elsewhere classified	0.052	0.948
T46.4 Angiotensin-converting-enzyme inhibitors	0.052	0.948
T46.3 Coronary vasodilators, not elsewhere classified	0.052	0.948
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.052	0.948
T46.1 Calcium-channel blockers	0.052	0.948
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.052	0.948
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.052	0.948
T47.8 Other agents primarily affecting the gastro-intestinal system	0.052	0.948
T47.7 Emetics	0.052	0.948
T47.6 Antidiarrhoeal drugs	0.052	0.948
T47.5 Digestants	0.052	0.948
T47.4 Other laxatives	0.052	0.948
T47.3 Saline and osmotic laxatives	0.052	0.948
T47.2 Stimulant laxatives	0.052	0.948
T47.1 Other antacids and anti-gastric-secretion drugs	0.052	0.948
T47.0 Histamine H(2)-receptor antagonists	0.052	0.948
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.052	0.948
T48.6 Antiasthmatics, not elsewhere classified	0.052	0.948
T48.5 Anti-common-cold drugs	0.052	0.948
T48.4 Expectorants	0.052	0.948
T48.3 Antitussives	0.052	0.948
T48.2 Other and unspecified agents primarily acting on muscles	0.052	0.948
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.052	0.948
T48.0 Oxytocic drugs	0.052	0.948
T49.9 Topical agent, unspecified	0.052	0.948
T49.8 Other topical agents	0.052	0.948
T49.7 Dental drugs, topically applied	0.052	0.948
T49.6 Otorhinolaryngological drugs and preparations	0.052	0.948
T49.5 Ophthalmological drugs and preparations	0.052	0.948
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.052	0.948
T49.3 Emollients, demulcents and protectants	0.052	0.948
T49.2 Local astringents and local detergents	0.052	0.948
T49.1 Antipruritics	0.052	0.948
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.052	0.948
T32 Corrosions classified according to extent of body surface involved	0.052	0.948
T30 Burn and corrosion, body region unspecified	0.052	0.948
T29 Burns and corrosions of multiple body regions	0.052	0.948
S51.0 Open wound of elbow	0.052	0.948
S92.0 Fracture of calcaneus	0.052	0.948
S00.0 Superficial injury of scalp	0.052	0.948
S65 Injury of blood vessels at wrist and hand level	0.052	0.948
S02.11 Fracture of base of skull (open)	0.052	0.948
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.051	0.948
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.051	0.949
S33.6 Sprain and strain of sacro-iliac joint	0.051	0.949
S33.5 Sprain and strain of lumbar spine	0.051	0.949
S33.4 Traumatic rupture of symphysis pubis	0.051	0.949
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.051	0.949
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.051	0.949
S33.1 Dislocation of lumbar vertebra	0.051	0.949
S33.0 Traumatic rupture of lumbar intervertebral disk	0.051	0.949
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.051	0.949
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.051	0.949
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.051	0.949
S34.4 Injury of lumbosacral plexus	0.051	0.949
S34.3 Injury of cauda equina	0.051	0.949
S34.2 Injury of nerve root of lumbar and sacral spine	0.051	0.949
S34.1 Other injury of lumbar spinal cord	0.051	0.949
S34.0 Concussion and oedema of lumbar spinal cord	0.051	0.949
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.051	0.949
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.051	0.949
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.051	0.949
S35.5 Injury of iliac blood vessels	0.051	0.949
S35.4 Injury of renal blood vessels	0.051	0.949
S35.3 Injury of portal or splenic vein	0.051	0.949
S35.2 Injury of coeliac or mesenteric artery	0.051	0.949
S35.1 Injury of inferior vena cava	0.051	0.949
S35.0 Injury of abdominal aorta	0.051	0.949
S36.9 Injury of unspecified intra-abdominal organ	0.051	0.949
S36.8 Injury of other intra-abdominal organs	0.051	0.949
S36.7 Injury of multiple intra-abdominal organs	0.051	0.949

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations