TreeWAS – Variant ID: rs3868542

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.999	0.001	0.000
M05-M14 Inflammatory polyarthropathies	0.999	0.001	0.000
E03 Other hypothyroidism	0.000	0.001	0.999
M05 Seropositive rheumatoid arthritis	0.998	0.002	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.998	0.002	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.003	0.997
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.003	0.997
E00-E07 Disorders of thyroid gland	0.000	0.004	0.996
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.994	0.006	0.000
L40.9 Psoriasis, unspecified	0.000	0.010	0.990
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.984	0.016	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.965	0.035	0.000
M45-M49 Spondylopathies	0.955	0.045	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.952	0.048	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.946	0.054	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.937	0.063	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.936	0.064	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.914	0.086	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.907	0.093	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.094	0.906
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.899	0.101	0.000
M70-M79 Other soft tissue disorders	0.896	0.104	0.000
M75 Shoulder lesions	0.894	0.106	0.000
M75.2 Bicipital tendinitis	0.888	0.112	0.000
E03.8 Other specified hypothyroidism	0.000	0.116	0.884
M06.3 Rheumatoid nodule	0.882	0.118	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.863	0.137	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.857	0.142	0.000
M00-M03 Infectious arthropathies	0.856	0.144	0.000
M75.1 Rotator cuff syndrome	0.856	0.144	0.000
R31 Unspecified haematuria	0.839	0.161	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.826	0.174	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.823	0.177	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.808	0.192	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.805	0.195	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.196	0.804
M06.0 Seronegative rheumatoid arthritis	0.803	0.196	0.000
M06.34 Rheumatoid nodule (Hand)	0.801	0.199	0.000
E06 Thyroiditis	0.000	0.202	0.798
M40-M43 Deforming dorsopathies	0.790	0.210	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.788	0.212	0.000
M49 Spondylopathies in diseases classified elsewhere	0.788	0.212	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.215	0.785
M75.4 Impingement syndrome of shoulder	0.764	0.236	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.763	0.237	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.763	0.237	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.754	0.246	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.259	0.741
M06.4 Inflammatory polyarthropathy	0.737	0.263	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.736	0.264	0.000
E06.3 Autoimmune thyroiditis	0.000	0.264	0.736
M14 Arthropathies in other diseases classified elsewhere	0.735	0.265	0.000
M00 Pyogenic arthritis	0.733	0.267	0.000
M02 Reactive arthropathies	0.729	0.270	0.000
M70.4 Prepatellar bursitis	0.724	0.276	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.716	0.284	0.000
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.716	0.284	0.000
M05.2 Rheumatoid vasculitis	0.716	0.284	0.000
M05.0 Felty's syndrome	0.716	0.284	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.716	0.284	0.000
E05.5 Thyroid crisis or storm	0.000	0.285	0.715
E05.4 Thyrotoxicosis factitia	0.000	0.285	0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.285	0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.286	0.714
E00 Congenital iodine-deficiency syndrome	0.000	0.286	0.714
M41 Scoliosis	0.714	0.286	0.000
M60-M63 Disorders of muscles	0.712	0.288	0.000
M08 Juvenile arthritis	0.710	0.290	0.000
M75.3 Calcific tendinitis of shoulder	0.706	0.294	0.000
M05.1 Rheumatoid lung disease	0.702	0.298	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.697	0.303	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.308	0.692
M06.8 Other specified rheumatoid arthritis	0.689	0.311	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.687	0.313	0.000
M46 Other inflammatory spondylopathies	0.682	0.318	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.678	0.322	0.000
M91-M94 Chondropathies	0.676	0.324	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.324	0.676
M70.5 Other bursitis of knee	0.676	0.324	0.000
M12 Other specific arthropathies	0.673	0.327	0.000
M75.8 Other shoulder lesions	0.672	0.328	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.668	0.332	0.000
M13 Other arthritis	0.667	0.333	0.000
M05.8 Other seropositive rheumatoid arthritis	0.666	0.334	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.663	0.337	0.000
M41.9 Scoliosis, unspecified	0.660	0.340	0.000
M06.33 Rheumatoid nodule (Forearm)	0.658	0.342	0.000
K75 Other inflammatory liver diseases	0.000	0.345	0.655
K75.4 Autoimmune hepatitis	0.000	0.353	0.647
K75.8 Other specified inflammatory liver diseases	0.000	0.354	0.646
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.645	0.355	0.000
M00.9 Pyogenic arthritis, unspecified	0.643	0.357	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.642	0.358	0.000
M40 Kyphosis and lordosis	0.641	0.359	0.000
E07 Other disorders of thyroid	0.000	0.361	0.639
M02.3 Reiter's disease	0.639	0.361	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.632	0.367	0.000
M06.38 Rheumatoid nodule (Other)	0.632	0.367	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.632	0.367	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.632	0.367	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.632	0.367	0.000
M46.4 Discitis, unspecified	0.631	0.369	0.000
K70-K77 Diseases of liver	0.000	0.371	0.629
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.614	0.386	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.614	0.386	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.612	0.388	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.612	0.388	0.000
M75.9 Shoulder lesion, unspecified	0.608	0.392	0.000
M11 Other crystal arthropathies	0.604	0.396	0.000
K73 Chronic hepatitis, not elsewhere classified	0.000	0.397	0.603
M10 Gout	0.602	0.398	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.399	0.600
K70 Alcoholic liver disease	0.000	0.401	0.599
M70.56 Other bursitis of knee-Lower Leg	0.596	0.404	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.595	0.405	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.585	0.415	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.585	0.415	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.584	0.416	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.421	0.579
M06.08 Seronegative rheumatoid arthritis (Other)	0.576	0.424	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.576	0.424	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.576	0.424	0.000
M14.6 Neuropathic arthropathy	0.575	0.425	0.000
M02.39 Reiter's disease (Site unspecified)	0.575	0.425	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.574	0.426	0.000
E06.4 Drug-induced thyroiditis	0.000	0.428	0.572
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.428	0.572
E06.0 Acute thyroiditis	0.000	0.428	0.572
M70.6 Trochanteric bursitis	0.568	0.432	0.000
M42 Spinal osteochondrosis	0.567	0.433	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.433	0.567
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.565	0.435	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.565	0.435	0.000
M70.1 Bursitis of hand	0.565	0.435	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.565	0.435	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.565	0.435	0.000
M49.4 Neuropathic spondylopathy	0.565	0.435	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.565	0.435	0.000
M49.2 Enterobacterial spondylitis	0.565	0.435	0.000
M49.1 Brucella spondylitis	0.565	0.435	0.000
M49.0 Tuberculosis of spine	0.565	0.435	0.000
E06.5 Other chronic thyroiditis	0.000	0.439	0.560
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.559	0.440	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.559	0.441	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.557	0.443	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.447	0.553
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.551	0.449	0.000
M60 Myositis	0.550	0.450	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.550	0.450	0.000
K74.0 Hepatic fibrosis	0.000	0.452	0.548
M13.8 Other specified arthritis	0.543	0.457	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.459	0.541
M13.1 Monoarthritis, not elsewhere classified	0.539	0.461	0.000
E05.8 Other thyrotoxicosis	0.000	0.461	0.538
M92 Other juvenile osteochondrosis	0.538	0.462	0.000
M41.8 Other forms of scoliosis	0.535	0.465	0.000
M07 Psoriatic and enteropathic arthropathies	0.531	0.469	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.528	0.472	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.528	0.472	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.528	0.472	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.528	0.472	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.528	0.472	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.528	0.472	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.528	0.472	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.528	0.472	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.528	0.472	0.000
E04 Other non-toxic goitre	0.000	0.472	0.528
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.527	0.473	0.000
M14.4 Arthropathy in amyloidosis	0.527	0.473	0.000
M14.3 Lipoid dermatoarthritis	0.527	0.473	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.527	0.473	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.527	0.473	0.000
M40.1 Other secondary kyphosis	0.527	0.473	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.527	0.473	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.526	0.474	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.526	0.474	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.525	0.475	0.000
M02.8 Other reactive arthropathies	0.523	0.477	0.000
M02.2 Postimmunisation arthropathy	0.523	0.477	0.000
M02.1 Postdysenteric arthropathy	0.523	0.477	0.000
M02.0 Arthropathy following intestinal bypass	0.523	0.477	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.522	0.477	0.000
K90 Intestinal malabsorption	0.000	0.477	0.523
M02.9 Reactive arthopathy, unspecified	0.522	0.478	0.000
M70.49 Prepatellar bursitis-Site unspec	0.519	0.481	0.000
M70.48 Prepatellar bursitis-Other	0.519	0.481	0.000
M70.47 Prepatellar bursitis-Ankle/Foot	0.519	0.481	0.000
M70.45 Prepatellar bursitis-Pelvic/Thigh	0.519	0.481	0.000
M70.44 Prepatellar bursitis-Hand	0.519	0.481	0.000
M70.43 Prepatellar bursitis-Forearm	0.519	0.481	0.000
M70.42 Prepatellar bursitis-Upper arm	0.519	0.481	0.000
M70.41 Prepatellar bursitis-Shldr region	0.519	0.481	0.000
M70.40 Prepatellar bursitis-Mult sites	0.519	0.481	0.000
K73.9 Chronic hepatitis, unspecified	0.000	0.481	0.519
K70.4 Alcoholic hepatic failure	0.000	0.482	0.518
M94 Other disorders of cartilage	0.517	0.483	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.513	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.513	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.513	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.513	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.513	0.487	0.000
M05.08 Felty's syndrome (Other)	0.513	0.487	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.513	0.487	0.000
M05.06 Felty's syndrome (Lower leg)	0.513	0.487	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.513	0.487	0.000
M05.04 Felty's syndrome (Hand)	0.513	0.487	0.000
M05.03 Felty's syndrome (Forearm)	0.513	0.487	0.000
M05.02 Felty's syndrome (Upper arm)	0.513	0.487	0.000
M05.01 Felty's syndrome (Shoulder region)	0.513	0.487	0.000
M05.00 Felty's syndrome (Multiple sites)	0.513	0.487	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.513	0.487	0.000
M05.28 Rheumatoid vasculitis (Other)	0.513	0.487	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.513	0.487	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.513	0.487	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.513	0.487	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.513	0.487	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.513	0.487	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.513	0.487	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.513	0.487	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.513	0.487	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.513	0.487	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.513	0.487	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.513	0.487	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.513	0.487	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.513	0.487	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.513	0.487	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.513	0.487	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.513	0.487	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.513	0.487	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.513	0.487	0.000
M75.81 Other shoulder lesions, right shoulder	0.513	0.487	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.488	0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.488	0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.488	0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.488	0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.488	0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.488	0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.488	0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.488	0.512
M41.4 Neuromuscular scoliosis	0.512	0.488	0.000
M41.3 Thoracogenic scoliosis	0.512	0.488	0.000
M41.2 Other idiopathic scoliosis	0.512	0.488	0.000
M41.1 Juvenile idiopathic scoliosis	0.512	0.488	0.000
M41.0 Infantile idiopathic scoliosis	0.512	0.488	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.512	0.488	0.000
M13.0 Polyarthritis, unspecified	0.511	0.489	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.511	0.489	0.000
M61 Calcification and ossification of muscle	0.511	0.489	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.510	0.490	0.000
M70.2 Olecranon bursitis	0.510	0.490	0.000
M08.9 Juvenile arthritis, unspecified	0.509	0.491	0.000
M08.8 Other juvenile arthritis	0.509	0.491	0.000
M08.4 Pauciarticular juvenile arthritis	0.509	0.491	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.509	0.491	0.000
M08.2 Juvenile arthritis with systemic onset	0.509	0.491	0.000
M08.1 Juvenile ankylosing spondylitis	0.509	0.491	0.000
M72 Fibroblastic disorders	0.505	0.495	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.505	0.495	0.000
M62 Other disorders of muscle	0.505	0.495	0.000
M05.18 Rheumatoid lung disease (Other)	0.503	0.496	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.503	0.496	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.503	0.496	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.503	0.496	0.000
M05.14 Rheumatoid lung disease (Hand)	0.503	0.496	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.503	0.496	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.503	0.496	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.503	0.496	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.503	0.496	0.000
M08.0 Juvenile rheumatoid arthritis	0.503	0.497	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.501	0.499
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.498	0.502	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.503	0.497
E04.0 Non-toxic diffuse goitre	0.000	0.505	0.495
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.494	0.506	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.494	0.506	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.494	0.506	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.494	0.506	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.494	0.506	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.494	0.506	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.494	0.506	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.494	0.506	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.494	0.506	0.000
M70.3 Other bursitis of elbow	0.493	0.507	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.493	0.507	0.000
M14.2 Diabetic arthropathy	0.493	0.507	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.492	0.508	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.491	0.509	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.491	0.509	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.490	0.510	0.000
M46.8 Other specified inflammatory spondylopathies	0.489	0.511	0.000
M46.5 Other infective spondylopathies	0.489	0.511	0.000
M41.5 Other secondary scoliosis	0.486	0.514	0.000
M70.59 Other bursitis of knee-Site unspec	0.485	0.515	0.000
M70.58 Other bursitis of knee-Other	0.485	0.515	0.000
M70.57 Other bursitis of knee-Ankle/Foot	0.485	0.515	0.000
M70.55 Other bursitis of knee-Pelvic/Thigh	0.485	0.515	0.000
M70.54 Other bursitis of knee-Hand	0.485	0.515	0.000
M70.53 Other bursitis of knee-Forearm	0.485	0.515	0.000
M70.52 Other bursitis of knee-Upper arm	0.485	0.515	0.000
M70.51 Other bursitis of knee-Shldr region	0.485	0.515	0.000
M70.50 Other bursitis of knee-Mult sites	0.485	0.515	0.000
M12.5 Traumatic arthropathy	0.483	0.517	0.000
M12.4 Intermittent hydrarthrosis	0.483	0.517	0.000
M12.1 Kaschin-Beck disease	0.483	0.517	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.483	0.517	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.481	0.519	0.000
M12.2 Villonodular synovitis (pigmented)	0.481	0.519	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.480	0.520	0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.479	0.521	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.479	0.521	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.479	0.521	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.479	0.521	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.479	0.521	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.479	0.521	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.479	0.521	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.478	0.522	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.478	0.522	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.478	0.522	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.478	0.522	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.478	0.522	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.478	0.522	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.478	0.522	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.478	0.522	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.478	0.522	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.478	0.522	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.477	0.523	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.524	0.476
M46.1 Sacro-iliitis, not elsewhere classified	0.476	0.524	0.000
E07.8 Other specified disorders of thyroid	0.000	0.526	0.474
M40.2 Other and unspecified kyphosis	0.474	0.526	0.000
M10.3 Gout due to impairment of renal function	0.474	0.526	0.000
M76 Enthesopathies of lower limb, excluding foot	0.473	0.527	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.473	0.527	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.473	0.527	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.473	0.527	0.000
K70.1 Alcoholic hepatitis	0.000	0.527	0.472
M46.42 Discitis, unspecified (Cervical region)	0.472	0.528	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.471	0.529	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.471	0.529	0.000
K75.2 Nonspecific reactive hepatitis	0.000	0.531	0.469
K75.1 Phlebitis of portal vein	0.000	0.531	0.469
E06.9 Thyroiditis, unspecified	0.000	0.533	0.466
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.466	0.534	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.465	0.535	0.000
M48 Other spondylopathies	0.465	0.535	0.000
E06.1 Subacute thyroiditis	0.000	0.537	0.463
M60.0 Infective myositis	0.462	0.538	0.000
M70.7 Other bursitis of hip	0.461	0.538	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.461	0.539	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.461	0.539	0.000
M73.8 Other soft tissue disorders in diseases classified elsewhere	0.460	0.539	0.000
M73.1 Syphilitic bursitis	0.460	0.539	0.000
M73.0 Gonococcal bursitis	0.460	0.539	0.000
M40.4 Other lordosis	0.459	0.541	0.000
M40.3 Flatback syndrome	0.459	0.541	0.000
M40.0 Postural kyphosis	0.459	0.541	0.000
M46.2 Osteomyelitis of vertebra	0.459	0.541	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.459	0.541	0.000
E07.1 Dyshormogenetic goitre	0.000	0.541	0.458
E07.0 Hypersecretion of calcitonin	0.000	0.541	0.458
M02.38 Reiter's disease (Other)	0.458	0.542	0.000
M02.37 Reiter's disease (Ankle and foot)	0.458	0.542	0.000
M02.36 Reiter's disease (Lower leg)	0.458	0.542	0.000
M02.35 Reiter's disease (Pelvic region and thigh)	0.458	0.542	0.000
M02.34 Reiter's disease (Hand)	0.458	0.542	0.000
M02.33 Reiter's disease (Forearm)	0.458	0.542	0.000
M02.32 Reiter's disease (Upper arm)	0.458	0.542	0.000
M02.31 Reiter's disease (Shoulder region)	0.458	0.542	0.000
M02.30 Reiter's disease (Multiple sites)	0.458	0.542	0.000
M40.5 Lordosis, unspecified	0.454	0.546	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.546	0.454
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.453	0.547	0.000
K70.0 Alcoholic fatty liver	0.000	0.547	0.453
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.453	0.547	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.453	0.547	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.453	0.547	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.453	0.547	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.453	0.547	0.000
K77 Liver disorders in diseases classified elsewhere	0.000	0.549	0.451
M12.3 Palindromic rheumatism	0.449	0.551	0.000
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.447	0.553	0.000
M40.14 Other secondary kyphosis (Thoracic region)	0.446	0.554	0.000
M13.89 Other specified arthritis (Site unspecified)	0.442	0.558	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.441	0.559	0.000
M01.8 Arthritis in other infectious and parasitic diseases classified elsewhere	0.440	0.560	0.000
M01.6 Arthritis in mycoses	0.440	0.560	0.000
M01.5 Arthritis in other viral diseases classified elsewhere	0.440	0.560	0.000
M01.4 Rubella arthritis	0.440	0.560	0.000
M01.3 Arthritis in other bacterial diseases classified elsewhere	0.440	0.560	0.000
M01.2 Arthritis in Lyme disease	0.440	0.560	0.000
M01.1 Tuberculous arthritis	0.440	0.560	0.000
M01.0 Meningococcal arthritis	0.440	0.560	0.000
M03.6 Reactive arthropathy in other diseases classified elsewhere	0.440	0.560	0.000
M03.2 Other postinfectious arthropathies in diseases classified elsewhere	0.440	0.560	0.000
M03.1 Postinfective arthropathy in syphilis	0.440	0.560	0.000
M03.0 Postmeningococcal arthritis	0.440	0.560	0.000
M13.80 Other specified arthritis (Multiple sites)	0.440	0.560	0.000
M46.0 Spinal enthesopathy	0.437	0.563	0.000
M00.86 Arthritis and polyarthritis due to other specified bacterial agents (Lower leg)	0.435	0.565	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.435	0.565	0.000
M11.8 Other specified crystal arthropathies	0.433	0.567	0.000
M11.1 Familial chondrocalcinosis	0.433	0.567	0.000
M11.0 Hydroxyapatite deposition disease	0.433	0.567	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.433	0.567	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.567	0.433
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.567	0.433
M10.4 Other secondary gout	0.431	0.568	0.000
M10.2 Drug-induced gout	0.431	0.568	0.000
M10.1 Lead-induced gout	0.431	0.568	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.570	0.430
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.428	0.571	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.578	0.422
M71 Other bursopathies	0.421	0.579	0.000
M11.9 Crystal arthropathy, unspecified	0.421	0.579	0.000
M77 Other enthesopathies	0.421	0.579	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.581	0.419
M94.8 Other specified disorders of cartilage	0.418	0.582	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.417	0.583	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.416	0.584	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.584	0.416
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.584	0.416
M92.6 Juvenile osteochondrosis of tarsus	0.414	0.586	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.410	0.590	0.000
M70.69 Trochanteric bursitis-Site unspec	0.407	0.593	0.000
M70.68 Trochanteric bursitis-Other	0.407	0.593	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.407	0.593	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.407	0.593	0.000
M70.64 Trochanteric bursitis-Hand	0.407	0.593	0.000
M70.63 Trochanteric bursitis-Forearm	0.407	0.593	0.000
M70.62 Trochanteric bursitis-Upper arm	0.407	0.593	0.000
M70.61 Trochanteric bursitis-Shldr region	0.407	0.593	0.000
M70.60 Trochanteric bursitis-Mult sites	0.407	0.593	0.000
M42.9 Spinal osteochondrosis, unspecified	0.406	0.593	0.000
M42.1 Adult osteochondrosis of spine	0.406	0.593	0.000
M42.0 Juvenile osteochondrosis of spine	0.406	0.593	0.000
K71 Toxic liver disease	0.000	0.593	0.406
M41.86 Other forms of scoliosis (Lumbar region)	0.406	0.594	0.000
M70.09 Chronic crepitant synovitis of hand and wrist-Site unspec	0.405	0.595	0.000
M70.08 Chronic crepitant synovitis of hand and wrist-Other	0.405	0.595	0.000
M70.07 Chronic crepitant synovitis of hand and wrist-Ankle/Foot	0.405	0.595	0.000
M70.06 Chronic crepitant synovitis of hand and wrist-Lower Leg	0.405	0.595	0.000
M70.05 Chronic crepitant synovitis of hand and wrist-Pelvic/Thigh	0.405	0.595	0.000
M70.04 Chronic crepitant synovitis of hand and wrist (Hand)	0.405	0.595	0.000
M70.03 Chronic crepitant synovitis of hand and wrist (Forearm)	0.405	0.595	0.000
M70.02 Chronic crepitant synovitis of hand and wrist-Upper arm	0.405	0.595	0.000
M70.01 Chronic crepitant synovitis of hand and wrist-Shldr region	0.405	0.595	0.000
M70.00 Chronic crepitant synovitis of hand and wrist (Multiple sites)	0.405	0.595	0.000
M70.19 Bursitis of hand-Site unspec	0.405	0.595	0.000
M70.18 Bursitis of hand-Other	0.405	0.595	0.000
M70.17 Bursitis of hand-Ankle/Foot	0.405	0.595	0.000
M70.16 Bursitis of hand-Lower Leg	0.405	0.595	0.000
M70.15 Bursitis of hand-Pelvic/Thigh	0.405	0.595	0.000
M70.14 Bursitis of hand-Hand	0.405	0.595	0.000
M70.13 Bursitis of hand-Forearm	0.405	0.595	0.000
M70.12 Bursitis of hand-Upper arm	0.405	0.595	0.000
M70.11 Bursitis of hand-Shldr region	0.405	0.595	0.000
M70.10 Bursitis of hand-Mult sites	0.405	0.595	0.000
M70.89 Other soft tissue disorders related to use, overuse and pressure (Site unspecified)	0.405	0.595	0.000
M70.88 Other soft tissue disorders related to use, overuse and pressure (Other)	0.405	0.595	0.000
M70.87 Other soft tissue disorders related to use, overuse and pressure (Ankle and foot)	0.405	0.595	0.000
M70.86 Other soft tissue disorders related to use, overuse and pressure (Lower leg)	0.405	0.595	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations