TreeWAS – Variant ID: rs4081724

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I42.0 Dilated cardiomyopathy	0.023	0.977	0.000
I42 Cardiomyopathy	0.020	0.980	0.000
I42.9 Cardiomyopathy, unspecified	0.018	0.982	0.000
I42.5 Other restrictive cardiomyopathy	0.017	0.983	0.000
I42.2 Other hypertrophic cardiomyopathy	0.016	0.984	0.000
I42.6 Alcoholic cardiomyopathy	0.016	0.984	0.000
Z97.4 Presence of external hearing-aid	0.016	0.984	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.985	0.015
I42.8 Other cardiomyopathies	0.015	0.985	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.014	0.986	0.000
I42.4 Endocardial fibroelastosis	0.014	0.986	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.014	0.986	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.986	0.014
C16.0 Cardia	0.000	0.986	0.014
C18.7 Sigmoid colon	0.000	0.986	0.014
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.987	0.013
C16 Malignant neoplasm of stomach	0.000	0.987	0.013
C18 Malignant neoplasm of colon	0.000	0.987	0.013
I42.1 Obstructive hypertrophic cardiomyopathy	0.012	0.988	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.988	0.012
C20 Malignant neoplasm of rectum	0.000	0.988	0.012
C18.9 Colon, unspecified	0.000	0.988	0.012
C22.9 Liver, unspecified	0.000	0.989	0.011
Z13.9 Special screening examination, unspecified	0.011	0.989	0.000
C23 Malignant neoplasm of gallbladder	0.000	0.990	0.010
C16.9 Stomach, unspecified	0.000	0.990	0.010
C22.0 Liver cell carcinoma	0.000	0.990	0.010
S01.8 Open wound of other parts of head	0.010	0.990	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.990	0.010
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.990	0.010
C22.7 Other specified carcinomas of liver	0.000	0.990	0.010
C22.4 Other sarcomas of liver	0.000	0.990	0.010
C22.3 Angiosarcoma of liver	0.000	0.990	0.010
C22.2 Hepatoblastoma	0.000	0.990	0.010
C16.8 Overlapping lesion of stomach	0.000	0.990	0.009
C16.4 Pylorus	0.000	0.990	0.009
C16.1 Fundus of stomach	0.000	0.990	0.009
C18.8 Overlapping lesion of colon	0.000	0.990	0.009
C16.3 Pyloric antrum	0.000	0.991	0.009
C21 Malignant neoplasm of anus and anal canal	0.000	0.991	0.009
C18.3 Hepatic flexure	0.000	0.991	0.009
C18.1 Appendix	0.000	0.991	0.009
C16.5 Lesser curvature of stomach, unspecified	0.000	0.991	0.009
C18.2 Ascending colon	0.000	0.991	0.009
C18.5 Splenic flexure	0.000	0.991	0.009
K66.0 Peritoneal adhesions	0.000	0.991	0.009
C16.6 Greater curvature of stomach, unspecified	0.000	0.992	0.008
C18.4 Transverse colon	0.000	0.992	0.008
C24.0 Extrahepatic bile duct	0.000	0.992	0.008
K60.2 Anal fissure, unspecified	0.008	0.992	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.992	0.008
C17 Malignant neoplasm of small intestine	0.000	0.992	0.008
S01 Open wound of head	0.008	0.992	0.000
C18.6 Descending colon	0.000	0.992	0.008
C16.2 Body of stomach	0.000	0.992	0.007
C26.9 Ill-defined sites within the digestive system	0.000	0.993	0.007
C24.9 Biliary tract, unspecified	0.000	0.993	0.007
C24.8 Overlapping lesion of biliary tract	0.000	0.993	0.007
C25 Malignant neoplasm of pancreas	0.000	0.993	0.007
S01.0 Open wound of scalp	0.007	0.993	0.000
C26.8 Overlapping lesion of digestive system	0.000	0.993	0.007
C26.1 Spleen	0.000	0.993	0.007
S01.3 Open wound of ear	0.007	0.993	0.000
C21.1 Anal canal	0.000	0.993	0.007
C21.2 Cloacogenic zone	0.000	0.993	0.007
S01.9 Open wound of head, part unspecified	0.007	0.993	0.000
C21.0 Anus, unspecified	0.000	0.993	0.007
C26.0 Intestinal tract, part unspecified	0.000	0.993	0.007
Z48.8 Other specified surgical follow-up care	0.000	0.993	0.007
C25.2 Tail of pancreas	0.000	0.993	0.006
Z48.9 Surgical follow-up care, unspecified	0.000	0.993	0.007
C15.3 Upper third of oesophagus	0.000	0.994	0.006
C15.4 Middle third of oesophagus	0.000	0.994	0.006
C15.8 Overlapping lesion of oesophagus	0.000	0.994	0.006
C15.2 Abdominal part of oesophagus	0.000	0.994	0.006
C15.1 Thoracic part of oesophagus	0.000	0.994	0.006
C15.0 Cervical part of oesophagus	0.000	0.994	0.006
S01.4 Open wound of cheek and temporomandibular area	0.006	0.994	0.000
C15.9 Oesophagus, unspecified	0.000	0.994	0.006
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.994	0.006
S01.1 Open wound of eyelid and periocular area	0.006	0.994	0.000
Z97 Presence of other devices	0.006	0.994	0.000
C25.1 Body of pancreas	0.000	0.994	0.006
C17.8 Overlapping lesion of small intestine	0.000	0.994	0.006
C17.3 Meckel's diverticulum	0.000	0.994	0.006
C17.1 Jejunum	0.000	0.994	0.006
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.006	0.994	0.000
Z48 Other surgical follow-up care	0.000	0.994	0.006
C25.8 Overlapping lesion of pancreas	0.000	0.994	0.005
C25.7 Other parts of pancreas	0.000	0.994	0.005
C25.4 Endocrine pancreas	0.000	0.994	0.005
S01.5 Open wound of lip and oral cavity	0.005	0.995	0.000
C24.1 Ampulla of Vater	0.000	0.995	0.005
Z96.0 Presence of urogenital implants	0.000	0.995	0.005
C17.0 Duodenum	0.000	0.995	0.005
C17.2 Ileum	0.000	0.995	0.005
C25.3 Pancreatic duct	0.000	0.995	0.005
C17.9 Small intestine, unspecified	0.000	0.995	0.005
I47.1 Supraventricular tachycardia	0.005	0.995	0.000
Z97.3 Presence of spectacles and contact lenses	0.005	0.995	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.005	0.995	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.005	0.995	0.000
S01.7 Multiple open wounds of head	0.005	0.995	0.000
I47.2 Ventricular tachycardia	0.004	0.996	0.000
M54.56 Low back pain (Lumbar region)	0.004	0.996	0.000
K66 Other disorders of peritoneum	0.000	0.996	0.004
C18.0 Caecum	0.000	0.996	0.004
Z97.0 Presence of artificial eye	0.004	0.996	0.000
I47 Paroxysmal tachycardia	0.004	0.996	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.004	0.996	0.000
S01.2 Open wound of nose	0.004	0.996	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.996	0.004
Z51.8 Other specified medical care	0.004	0.996	0.000
M62.88 Other specified disorders of muscle (Other)	0.004	0.996	0.000
I47.0 Reentry ventricular arrhythmia	0.004	0.996	0.000
M62.8 Other specified disorders of muscle	0.004	0.996	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.003	0.996	0.000
Q61.3 Polycystic kidney, unspecified	0.004	0.996	0.000
M47.9 Spondylosis, unspecified	0.004	0.996	0.000
K66.1 Haemoperitoneum	0.000	0.997	0.003
Z97.5 Presence of (intra-uterine) contraceptive device	0.003	0.997	0.000
K66.9 Disorder of peritoneum, unspecified	0.000	0.997	0.003
C15.5 Lower third of oesophagus	0.000	0.997	0.003
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.003	0.997	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
Z97.8 Presence of other specified devices	0.003	0.997	0.000
C25.9 Pancreas, unspecified	0.000	0.997	0.003
N03.9 Unspecified	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.997	0.003
Y57.5 X-ray contrast media	0.003	0.997	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.003	0.997	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.003	0.997	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.003	0.997	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.003	0.997	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.003	0.997	0.000
M62.84 Other specified disorders of muscle (Hand)	0.003	0.997	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.003	0.997	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.003	0.997	0.000
L85.8 Other specified epidermal thickening	0.000	0.997	0.003
Q61 Cystic kidney disease	0.003	0.997	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.003	0.997	0.000
C25.0 Head of pancreas	0.000	0.997	0.002
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.003	0.997	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.997	0.003
Y45.2 Propionic acid derivatives	0.000	0.997	0.002
Y45.0 Opioids and related analgesics	0.000	0.997	0.003
E11.4 With neurological complications	0.002	0.998	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
M62 Other disorders of muscle	0.002	0.998	0.000
M54.59 Low back pain (Site unspecified)	0.002	0.998	0.000
N48.8 Other specified disorders of penis	0.002	0.998	0.000
K60 Fissure and fistula of anal and rectal regions	0.002	0.998	0.000
M54.50 Low back pain (Multiple sites in spine)	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.000	0.998	0.002
M24.02 Loose body in joint (Upper arm)	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
F20.9 Schizophrenia, unspecified	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
N03 Chronic nephritic syndrome	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.998	0.002
K66.8 Other specified disorders of peritoneum	0.000	0.998	0.002
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
M54.5 Low back pain	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.002	0.998	0.000
N03.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.002	0.998	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.002	0.998	0.000
M62.6 Muscle strain	0.002	0.998	0.000
F43.2 Adjustment disorders	0.000	0.998	0.002
K60.0 Acute anal fissure	0.002	0.998	0.000
I63 Cerebral infarction	0.002	0.998	0.000
K37 Unspecified appendicitis	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
Z92.3 Personal history of irradiation	0.000	0.998	0.002
K65-K67 Diseases of peritoneum	0.000	0.998	0.002
M62.9 Disorder of muscle, unspecified	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
M62.4 Contracture of muscle	0.002	0.998	0.000
M62.3 Immobility syndrome (paraplegic)	0.002	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.002	0.998	0.000
M62.0 Diastasis of muscle	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.002	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
N03.8 Other	0.002	0.998	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N03.6 Dense deposit disease	0.002	0.998	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N03.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
N03.0 Minor glomerular abnormality	0.002	0.998	0.000
R06.2 Wheezing	0.000	0.998	0.002
Y45.4 Antirheumatics	0.000	0.998	0.002
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
K60.5 Anorectal fistula	0.002	0.998	0.000
I35.0 Aortic (valve) stenosis	0.002	0.998	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
M54.54 Low back pain-Thoracic	0.002	0.998	0.000
M54.53 Low back pain-Cervicothoracic	0.002	0.998	0.000
M54.52 Low back pain-Cervical	0.002	0.998	0.000
M54.51 Low back pain-Occipit-atl-axl	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.000	0.998	0.002
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
F20 Schizophrenia	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.002	0.998	0.000
O04.9 Complete or unspecified, without complication	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.000	0.998	0.002
M62.65 Muscle strain (Pelvic region and thigh)	0.001	0.998	0.000
S82.00 Fracture of patella (closed)	0.002	0.998	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.998	0.002
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.998	0.000
M62.69 Muscle strain (Site unspecified)	0.001	0.998	0.000
M62.68 Muscle strain (Other)	0.001	0.998	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.998	0.000
M62.64 Muscle strain (Hand)	0.001	0.998	0.000
M62.63 Muscle strain (Forearm)	0.001	0.998	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.998	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.998	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
K60.4 Rectal fistula	0.002	0.998	0.000
M24.0 Loose body in joint	0.002	0.998	0.000
Z59.1 Inadequate housing	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.002	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.002	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.002	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.002	0.998	0.000
S14.3 Injury of brachial plexus	0.002	0.998	0.000
Y45.1 Salicylates	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.998	0.000
M62.08 Diastasis of muscle (Other)	0.001	0.998	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.998	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.998	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.998	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.998	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.998	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.998	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.998	0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.001	0.998	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.001	0.998	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.001	0.998	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.001	0.998	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.001	0.998	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.001	0.998	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.001	0.998	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.001	0.998	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.001	0.998	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.001	0.998	0.000
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.001	0.998	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.001	0.998	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.001	0.998	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.001	0.998	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.001	0.998	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.001	0.998	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.001	0.998	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.001	0.998	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.001	0.998	0.000
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.001	0.998	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.001	0.998	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.001	0.998	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.001	0.998	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.001	0.998	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.001	0.998	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.001	0.998	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.001	0.998	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.001	0.998	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.001	0.998	0.000
M62.49 Contracture of muscle (Site unspecified)	0.001	0.998	0.000
M62.48 Contracture of muscle (Other)	0.001	0.998	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.001	0.998	0.000
M62.46 Contracture of muscle (Lower leg)	0.001	0.998	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.44 Contracture of muscle (Hand)	0.001	0.998	0.000
M62.43 Contracture of muscle (Forearm)	0.001	0.998	0.000
M62.42 Contracture of muscle (Upper arm)	0.001	0.998	0.000
M62.41 Contracture of muscle (Shoulder region)	0.001	0.998	0.000
M62.40 Contracture of muscle (Multiple sites)	0.001	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.001	0.998	0.000
M62.98 Disorder of muscle, unspecified (Other)	0.001	0.998	0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.001	0.998	0.000
M62.96 Disorder of muscle, unspecified (Lower leg)	0.001	0.998	0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M62.94 Disorder of muscle, unspecified (Hand)	0.001	0.998	0.000
M62.93 Disorder of muscle, unspecified (Forearm)	0.001	0.998	0.000
M62.92 Disorder of muscle, unspecified (Upper arm)	0.001	0.998	0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.001	0.998	0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.001	0.998	0.000
N41.0 Acute prostatitis	0.002	0.998	0.000
N48.4 Impotence of organic origin	0.002	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.002	0.998	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.998	0.001
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.002	0.998	0.000
I08 Multiple valve diseases	0.002	0.998	0.000
F20.5 Residual schizophrenia	0.001	0.998	0.000
I63.8 Other cerebral infarction	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
Z63.9 Problem related to primary support group, unspecified	0.001	0.998	0.000
Z63.3 Absence of family member	0.001	0.998	0.000
Z63.2 Inadequate family support	0.001	0.998	0.000
Z63.1 Problems in relationship with parents and in-laws	0.001	0.998	0.000
K65 Peritonitis	0.000	0.998	0.002
Q44.7 Other congenital malformations of liver	0.001	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.001	0.998	0.000
Q44.4 Choledochal cyst	0.001	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.001	0.998	0.000
Q44.2 Atresia of bile ducts	0.001	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.001	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.001	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.002	0.998	0.000
K60.3 Anal fistula	0.002	0.998	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.002	0.998	0.000
Z56.0 Unemployment, unspecified	0.001	0.998	0.000
M54.55 Low back pain (Thoracolumbar region)	0.001	0.998	0.000
F20.8 Other schizophrenia	0.001	0.998	0.000
F20.6 Simple schizophrenia	0.001	0.998	0.000
F20.4 Postschizophrenic depression	0.001	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.998	0.000
F20.2 Catatonic schizophrenia	0.001	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.998	0.000
Q63 Other congenital malformations of kidney	0.001	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
M24.03 Loose body in joint (Forearm)	0.001	0.998	0.000
Z59 Problems related to housing and economic circumstances	0.001	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.001	0.998	0.000
S62.50 Fracture of thumb (closed)	0.001	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.998	0.001
W10.8 Other specified place	0.000	0.998	0.001
M24.09 Loose body in joint (Site unspecified)	0.001	0.999	0.000
M24.08 Loose body in joint (Other)	0.001	0.999	0.000
M24.06 Loose body in joint-Lower leg	0.001	0.999	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.04 Loose body in joint (Hand)	0.001	0.999	0.000
M24.00 Loose body in joint (Multiple sites)	0.001	0.999	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.999	0.000
N48.6 Balanitis xerotica obliterans	0.001	0.999	0.000
S14.6 Injury of other and unspecified nerves of neck	0.001	0.999	0.000
S14.5 Injury of cervical sympathetic nerves	0.001	0.999	0.000
S14.4 Injury of peripheral nerves of neck	0.001	0.999	0.000
S14.2 Injury of nerve root of cervical spine	0.001	0.999	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.001	0.999	0.000
Y57.7 Vitamins, not elsewhere classified	0.001	0.999	0.000
Y57.6 Other diagnostic agents	0.001	0.999	0.000
Y57.4 Pharmaceutical excipients	0.001	0.999	0.000
Y57.3 Alcohol deterrents	0.001	0.999	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
Y57.1 Lipotropic drugs	0.001	0.999	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.999	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.001	0.999	0.000
Z57.8 Occupational exposure to other risk-factors	0.001	0.999	0.000
Z57.7 Occupational exposure to vibration	0.001	0.999	0.000
Z57.6 Occupational exposure to extreme temperature	0.001	0.999	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.001	0.999	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.001	0.999	0.000
Z57.1 Occupational exposure to radiation	0.001	0.999	0.000
Z57.0 Occupational exposure to noise	0.001	0.999	0.000
Z63.0 Problems in relationship with spouse or partner	0.001	0.999	0.000
Q45 Other congenital malformations of digestive system	0.001	0.999	0.000
Q40 Other congenital malformations of upper alimentary tract	0.001	0.999	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.001	0.999	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.999	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.001	0.999	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.999	0.001
K67.3 Tuberculous peritonitis	0.000	0.999	0.001
K67.2 Syphilitic peritonitis	0.000	0.999	0.001
K67.1 Gonococcal peritonitis	0.000	0.999	0.001
K67.0 Chlamydial peritonitis	0.000	0.999	0.001
K81.9 Cholecystitis, unspecified	0.000	0.999	0.001
N48.9 Disorder of penis, unspecified	0.001	0.999	0.000
Q45.8 Other specified congenital malformations of digestive system	0.001	0.999	0.000
L85 Other epidermal thickening	0.000	0.999	0.001
N48 Other disorders of penis	0.001	0.999	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
I08.9 Multiple valve disease, unspecified	0.001	0.999	0.000
I89.0 Lymphoedema, not elsewhere classified	0.000	0.999	0.001
M24.2 Disorder of ligament	0.001	0.999	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.999	0.000
Q28 Other congenital malformations of circulatory system	0.001	0.999	0.000
M47 Spondylosis	0.001	0.999	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.001	0.999	0.000
G82.1 Spastic paraplegia	0.001	0.999	0.000
Q63.0 Accessory kidney	0.001	0.999	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.001	0.999	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.001	0.999	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.999	0.000
Q64 Other congenital malformations of urinary system	0.001	0.999	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.999	0.000
C77.9 Lymph node, unspecified	0.000	0.999	0.001
M11.26 Other chondrocalcinosis (Lower leg)	0.001	0.999	0.000
H11.1 Conjunctival degenerations and deposits	0.000	0.999	0.001
H54.4 Blindness, one eye	0.001	0.999	0.000
I08.8 Other multiple valve diseases	0.001	0.999	0.000
M24.1 Other articular cartilage disorders	0.001	0.999	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.001	0.999	0.000
Q63.8 Other specified congenital malformations of kidney	0.001	0.999	0.000
Q63.3 Hyperplastic and giant kidney	0.001	0.999	0.000
Q63.2 Ectopic kidney	0.001	0.999	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.001	0.999	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.001	0.999	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.001	0.999	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.999	0.001
T17.2 Foreign body in pharynx	0.000	0.999	0.001
Y57.8 Other drugs and medicaments	0.001	0.999	0.000
Z34.0 Supervision of normal first pregnancy	0.001	0.999	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.001	0.999	0.000
Z59.7 Insufficient social insurance and welfare support	0.001	0.999	0.000
Z59.6 Low income	0.001	0.999	0.000
Z59.5 Extreme poverty	0.001	0.999	0.000
Z59.4 Lack of adequate food	0.001	0.999	0.000
Z59.3 Problems related to living in residential institution	0.001	0.999	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.001	0.999	0.000
M24 Other specific joint derangements	0.001	0.999	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.001	0.999	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.001	0.999	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.001	0.999	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.001	0.999	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.001	0.999	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.999	0.000
L85.9 Epidermal thickening, unspecified	0.000	0.999	0.001
M24.4 Recurrent dislocation and subluxation of joint	0.001	0.999	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.001	0.999	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.001	0.999	0.000
Q40.2 Other specified congenital malformations of stomach	0.001	0.999	0.000
Q40.1 Congenital hiatus hernia	0.001	0.999	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.001	0.999	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.001	0.999	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.001	0.999	0.000
Q45.2 Congenital pancreatic cyst	0.001	0.999	0.000
Q45.1 Annular pancreas	0.001	0.999	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.001	0.999	0.000
S12.1 Fracture of second cervical vertebra	0.001	0.999	0.000
Z56 Problems related to employment and unemployment	0.001	0.999	0.000
K60.1 Chronic anal fissure	0.001	0.999	0.000
N48.3 Priapism	0.001	0.999	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.001	0.999	0.000
R47.1 Dysarthria and anarthria	0.001	0.999	0.000
M24.24 Disorder of ligament (Hand)	0.001	0.999	0.000
L85.3 Xerosis cutis	0.000	0.999	0.001
L85.2 Keratosis punctata (palmaris et plantaris)	0.000	0.999	0.001
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.000	0.999	0.001
L85.0 Acquired ichthyosis	0.000	0.999	0.001
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.999	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.999	0.000
Q28.1 Other malformations of precerebral vessels	0.001	0.999	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.999	0.000
Q38.7 Pharyngeal pouch	0.001	0.999	0.000
Z99.1 Dependence on respirator	0.001	0.999	0.000
S12 Fracture of neck	0.001	0.999	0.000
M24.29 Disorder of ligament (Site unspecified)	0.001	0.999	0.000
M24.28 Disorder of ligament (Other)	0.001	0.999	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.001	0.999	0.000
M24.22 Disorder of ligament (Upper arm)	0.001	0.999	0.000
M24.20 Disorder of ligament (Multiple sites)	0.001	0.999	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.999	0.001
M47.0 Anterior spinal and vertebral artery compression syndromes	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations