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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs41272114
log Bayes Factor = 9.8013
Chromosome 6   position 161,006,077  (GRCh37) Explore rs41272114 on Ensembl!
Variant rs41272114 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.001 0.999
Chapter IX Diseases of the circulatory system
0.000 0.002 0.998
I30-I52 Other forms of heart disease
0.000 0.005 0.995
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.005 0.995
I20.0 Unstable angina
0.000 0.006 0.994
E78.0 Pure hypercholesterolaemia
0.000 0.008 0.992
I73 Other peripheral vascular diseases
0.000 0.010 0.990
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.010 0.990
I73.9 Peripheral vascular disease, unspecified
0.000 0.015 0.985
I20.9 Angina pectoris, unspecified
0.000 0.020 0.980
I49 Other cardiac arrhythmias
0.000 0.038 0.962
I31 Other diseases of pericardium
0.000 0.053 0.947
I22 Subsequent myocardial infarction
0.000 0.064 0.936
I51 Complications and ill-defined descriptions of heart disease
0.000 0.079 0.921
I49.5 Sick sinus syndrome
0.000 0.097 0.903
I74 Arterial embolism and thrombosis
0.000 0.099 0.901
I35 Nonrheumatic aortic valve disorders
0.000 0.108 0.892
I21 Acute myocardial infarction
0.000 0.109 0.891
I10-I15 Hypertensive diseases
0.000 0.117 0.883
I24 Other acute ischaemic heart diseases
0.000 0.123 0.877
I05-I09 Chronic rheumatic heart diseases
0.000 0.124 0.876
I31.3 Pericardial effusion (noninflammatory)
0.000 0.126 0.874
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.135 0.865
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.136 0.864
I50 Heart failure
0.000 0.144 0.856
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.145 0.855
I51.7 Cardiomegaly
0.000 0.161 0.839
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.163 0.837
I73.0 Raynaud's syndrome
0.000 0.167 0.833
I49.9 Cardiac arrhythmia, unspecified
0.000 0.168 0.832
I31.9 Disease of pericardium, unspecified
0.000 0.180 0.820
I51.8 Other ill-defined heart diseases
0.000 0.181 0.819
I08 Multiple valve diseases
0.000 0.187 0.813
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.197 0.803
E78.5 Hyperlipidaemia, unspecified
0.000 0.199 0.801
I38 Endocarditis, valve unspecified
0.000 0.209 0.791
I08.0 Disorders of both mitral and aortic valves
0.000 0.212 0.788
I34 Nonrheumatic mitral valve disorders
0.000 0.219 0.781
I49.0 Ventricular fibrillation and flutter
0.000 0.221 0.779
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.234 0.766
I50.0 Congestive heart failure
0.000 0.240 0.760
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.250 0.750
I49.1 Atrial premature depolarisation
0.000 0.251 0.749
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.256 0.744
I74.5 Embolism and thrombosis of iliac artery
0.000 0.263 0.737
I10 Essential (primary) hypertension
0.000 0.263 0.737
I20.8 Other forms of angina pectoris
0.000 0.265 0.735
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.266 0.734
I47 Paroxysmal tachycardia
0.000 0.267 0.733
I35.9 Aortic valve disorder, unspecified
0.000 0.270 0.730
I72 Other aneurysm
0.000 0.275 0.725
I35.0 Aortic (valve) stenosis
0.000 0.278 0.722
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.279 0.721
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I25.4 Coronary artery aneurysm
0.000 0.283 0.717
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.284 0.716
I52 Other heart disorders in diseases classified elsewhere
0.000 0.286 0.714
I48 Atrial fibrillation and flutter
0.000 0.286 0.714
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.286 0.714
I41 Myocarditis in diseases classified elsewhere
0.000 0.286 0.714
I40 Acute myocarditis
0.000 0.286 0.714
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.286 0.714
I36 Nonrheumatic tricuspid valve disorders
0.000 0.286 0.714
I32 Pericarditis in diseases classified elsewhere
0.000 0.286 0.714
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.287 0.713
I78 Diseases of capillaries
0.000 0.290 0.710
I73.8 Other specified peripheral vascular diseases
0.000 0.290 0.710
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.290 0.710
I25.5 Ischaemic cardiomyopathy
0.000 0.292 0.708
I12 Hypertensive renal disease
0.000 0.293 0.707
I35.8 Other aortic valve disorders
0.000 0.294 0.706
I24.8 Other forms of acute ischaemic heart disease
0.000 0.305 0.695
I49.2 Junctional premature depolarisation
0.000 0.310 0.690
I50.9 Heart failure, unspecified
0.000 0.310 0.690
I70 Atherosclerosis
0.000 0.312 0.688
I30 Acute pericarditis
0.000 0.313 0.687
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.316 0.684
I21.9 Acute myocardial infarction, unspecified
0.000 0.318 0.682
I11 Hypertensive heart disease
0.000 0.320 0.680
I31.8 Other specified diseases of pericardium
0.000 0.321 0.679
I31.2 Haemopericardium, not elsewhere classified
0.000 0.321 0.679
I31.1 Chronic constrictive pericarditis
0.000 0.321 0.679
I31.0 Chronic adhesive pericarditis
0.000 0.321 0.679
I49.4 Other and unspecified premature depolarisation
0.000 0.324 0.676
I22.8 Subsequent myocardial infarction of other sites
0.000 0.329 0.671
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.329 0.671
I37 Pulmonary valve disorders
0.000 0.330 0.670
I34.0 Mitral (valve) insufficiency
0.000 0.331 0.669
I51.6 Cardiovascular disease, unspecified
0.000 0.340 0.660
I51.5 Myocardial degeneration
0.000 0.340 0.660
I51.4 Myocarditis, unspecified
0.000 0.340 0.660
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.340 0.660
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.340 0.660
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.340 0.660
I51.0 Cardiac septal defect, acquired
0.000 0.340 0.660
I49.3 Ventricular premature depolarisation
0.000 0.344 0.656
E78.8 Other disorders of lipoprotein metabolism
0.000 0.346 0.654
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.346 0.654
I20.1 Angina pectoris with documented spasm
0.000 0.348 0.652
I33 Acute and subacute endocarditis
0.000 0.349 0.651
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.354 0.646
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.354 0.646
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.354 0.646
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.354 0.646
I77 Other disorders of arteries and arterioles
0.000 0.355 0.645
I25.3 Aneurysm of heart
0.000 0.358 0.642
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.359 0.641
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.361 0.639
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.361 0.639
I15 Secondary hypertension
0.000 0.367 0.633
I13 Hypertensive heart and renal disease
0.000 0.367 0.633
I24.1 Dressler's syndrome
0.000 0.371 0.629
I09 Other rheumatic heart diseases
0.000 0.372 0.628
I06 Rheumatic aortic valve diseases
0.000 0.372 0.628
E78.6 Lipoprotein deficiency
0.000 0.387 0.613
E78.4 Other hyperlipidaemia
0.000 0.387 0.613
E78.3 Hyperchylomicronaemia
0.000 0.387 0.613
I46 Cardiac arrest
0.000 0.392 0.608
I71 Aortic aneurysm and dissection
0.000 0.399 0.601
I49.8 Other specified cardiac arrhythmias
0.000 0.399 0.601
I05 Rheumatic mitral valve diseases
0.000 0.407 0.593
I08.8 Other multiple valve diseases
0.000 0.415 0.585
I08.9 Multiple valve disease, unspecified
0.000 0.417 0.583
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.422 0.578
I07 Rheumatic tricuspid valve diseases
0.000 0.424 0.576
I12.9 Hypertensive renal disease without renal failure
0.000 0.425 0.575
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.432 0.568
E78.1 Pure hyperglyceridaemia
0.000 0.436 0.564
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.440 0.560
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.440 0.560
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.440 0.560
E78.2 Mixed hyperlipidaemia
0.000 0.442 0.558
I78.1 Naevus, nonneoplastic
0.000 0.442 0.558
I72.4 Aneurysm of artery of lower extremity
0.000 0.444 0.556
I47.2 Ventricular tachycardia
0.000 0.460 0.540
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.465 0.535
I25.2 Old myocardial infarction
0.000 0.467 0.533
I47.0 Reentry ventricular arrhythmia
0.000 0.475 0.525
I72.9 Aneurysm of unspecified site
0.000 0.480 0.520
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.480 0.520
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.480 0.520
I72.3 Aneurysm of iliac artery
0.000 0.480 0.520
I72.2 Aneurysm of renal artery
0.000 0.480 0.520
I72.1 Aneurysm of artery of upper extremity
0.000 0.480 0.520
I12.0 Hypertensive renal disease with renal failure
0.000 0.483 0.517
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I02 Rheumatic chorea
0.000 0.487 0.513
I01 Rheumatic fever with heart involvement
0.000 0.487 0.513
I00 Rheumatic fever without mention of heart involvement
0.000 0.487 0.513
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.487 0.513
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.488 0.512
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.488 0.512
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.488 0.512
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.488 0.512
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.488 0.512
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.488 0.512
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.488 0.512
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.488 0.512
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.488 0.512
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.488 0.512
I40.9 Acute myocarditis, unspecified
0.000 0.488 0.512
I40.8 Other acute myocarditis
0.000 0.488 0.512
I40.1 Isolated myocarditis
0.000 0.488 0.512
I40.0 Infective myocarditis
0.000 0.488 0.512
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.488 0.512
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.488 0.512
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.488 0.512
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.488 0.512
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.488 0.512
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.488 0.512
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.488 0.512
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.488 0.512
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.488 0.512
I48.4 Atypical atrial flutter
0.000 0.488 0.512
I48.3 Typical atrial flutter
0.000 0.488 0.512
I48.2 Chronic atrial fibrillation
0.000 0.488 0.512
I48.1 Persistent atrial fibrillation
0.000 0.488 0.512
I48.0 Paroxysmal atrial fibrillation
0.000 0.488 0.512
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.488 0.512
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.488 0.512
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.488 0.512
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.488 0.511
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.489 0.511
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.489 0.511
I79.1 Aortitis in diseases classified elsewhere
0.000 0.489 0.511
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.489 0.511
I72.8 Aneurysm of other specified arteries
0.000 0.490 0.510
I78.9 Disease of capillaries, unspecified
0.000 0.491 0.509
I78.8 Other diseases of capillaries
0.000 0.491 0.509
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.491 0.509
I72.0 Aneurysm of carotid artery
0.000 0.498 0.502
I70.0 Atherosclerosis of aorta
0.000 0.506 0.494
I70.9 Generalised and unspecified atherosclerosis
0.000 0.506 0.494
I70.8 Atherosclerosis of other arteries
0.000 0.506 0.494
I70.1 Atherosclerosis of renal artery
0.000 0.506 0.494
I74.8 Embolism and thrombosis of other arteries
0.000 0.507 0.493
I30.8 Other forms of acute pericarditis
0.000 0.507 0.493
I30.1 Infective pericarditis
0.000 0.507 0.493
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.507 0.493
I50.1 Left ventricular failure
0.000 0.510 0.490
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.512 0.488
I42 Cardiomyopathy
0.000 0.512 0.487
I44 Atrioventricular and left bundle-branch block
0.000 0.515 0.484
I51.9 Heart disease, unspecified
0.000 0.516 0.483
I77.1 Stricture of artery
0.000 0.517 0.483
I37.9 Pulmonary valve disorder, unspecified
0.000 0.520 0.480
I37.8 Other pulmonary valve disorders
0.000 0.520 0.480
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.520 0.480
I37.0 Pulmonary valve stenosis
0.000 0.520 0.480
I35.1 Aortic (valve) insufficiency
0.000 0.520 0.480
I47.1 Supraventricular tachycardia
0.000 0.523 0.477
I34.1 Mitral (valve) prolapse
0.000 0.523 0.477
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.531 0.468
I33.9 Acute endocarditis, unspecified
0.000 0.533 0.467
I30.9 Acute pericarditis, unspecified
0.000 0.533 0.466
I77.5 Necrosis of artery
0.000 0.537 0.463
I77.4 Coeliac artery compression syndrome
0.000 0.537 0.463
I77.3 Arterial fibromuscular dysplasia
0.000 0.537 0.463
I77.2 Rupture of artery
0.000 0.537 0.463
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.543 0.457
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.546 0.454
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.546 0.454
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.546 0.454
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.546 0.454
I15.9 Seconday hypertension, unspecified
0.000 0.546 0.454
I15.8 Other secondary hypertension
0.000 0.546 0.454
I15.2 Hypertension secondary to endocrine disorders
0.000 0.546 0.454
I15.1 Hypertension secondary to other renal disorders
0.000 0.546 0.454
I15.0 Renovascular hypertension
0.000 0.546 0.454
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.549 0.450
I06.8 Other rheumatic aortic valve diseases
0.000 0.549 0.450
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.549 0.450
I06.1 Rheumatic aortic insufficiency
0.000 0.549 0.450
I06.0 Rheumatic aortic stenosis
0.000 0.549 0.450
I09.9 Rheumatic heart disease, unspecified
0.000 0.549 0.450
I09.8 Other specified rheumatic heart diseases
0.000 0.549 0.450
I09.2 Chronic rheumatic pericarditis
0.000 0.549 0.450
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.549 0.450
I09.0 Rheumatic myocarditis
0.000 0.549 0.450
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.557 0.443
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.559 0.441
I05.9 Mitral valve disease, unspecified
0.000 0.560 0.440
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.562 0.438
I37.1 Pulmonary valve insufficiency
0.000 0.563 0.436
I46.1 Sudden cardiac death, so described
0.000 0.564 0.436
I77.8 Other specified disorders of arteries and arterioles
0.000 0.567 0.433
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.569 0.431
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.569 0.431
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.569 0.431
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.569 0.431
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.569 0.431
I05.8 Other mitral valve diseases
0.000 0.575 0.425
I05.2 Mitral stenosis with insufficiency
0.000 0.575 0.425
I71.0 Dissection of aorta [any part]
0.000 0.575 0.425
I45 Other conduction disorders
0.000 0.579 0.421
I42.9 Cardiomyopathy, unspecified
0.000 0.582 0.417
I44.1 Atrioventricular block, second degree
0.000 0.583 0.417
I07.9 Tricuspid valve disease, unspecified
0.000 0.587 0.413
I07.8 Other tricuspid valve diseases
0.000 0.587 0.413
I07.2 Tricuspid stenosis with insufficiency
0.000 0.587 0.413
I07.0 Tricuspid stenosis
0.000 0.587 0.413
I77.6 Arteritis, unspecified
0.000 0.589 0.411
I05.0 Mitral stenosis
0.000 0.589 0.411
I33.0 Acute and subacute infective endocarditis
0.000 0.595 0.404
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.597 0.402
I46.0 Cardiac arrest with successful resuscitation
0.000 0.605 0.395
I77.0 Arteriovenous fistula, acquired
0.000 0.609 0.391
I05.1 Rheumatic mitral insufficiency
0.000 0.611 0.388
I46.9 Cardiac arrest, unspecified
0.000 0.616 0.384
I44.2 Atrioventricular block, complete
0.000 0.622 0.377
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.632 0.368
I01.8 Other acute rheumatic heart disease
0.000 0.632 0.368
I01.2 Acute rheumatic myocarditis
0.000 0.632 0.368
I01.1 Acute rheumatic endocarditis
0.000 0.632 0.368
I01.0 Acute rheumatic pericarditis
0.000 0.632 0.368
I02.9 Rheumatic chorea without heart involvement
0.000 0.632 0.368
I02.0 Rheumatic chorea with heart involvement
0.000 0.632 0.368
I21.4 Acute subendocardial myocardial infarction
0.000 0.639 0.360
I07.1 Tricuspid insufficiency
0.000 0.640 0.360
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.642 0.358
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.645 0.355
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.646 0.354
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.646 0.354
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.646 0.354
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.646 0.354
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.646 0.354
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.646 0.354
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.646 0.354
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.646 0.353
I42.8 Other cardiomyopathies
0.000 0.650 0.350
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.650 0.349
I42.5 Other restrictive cardiomyopathy
0.000 0.650 0.349
I42.4 Endocardial fibroelastosis
0.000 0.650 0.349
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.650 0.349
I44.5 Left posterior fascicular block
0.000 0.652 0.347
I44.4 Left anterior fascicular block
0.000 0.652 0.347
I44.3 Other and unspecified atrioventricular block
0.000 0.652 0.347
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.664 0.336
I44.6 Other and unspecified fascicular block
0.000 0.674 0.326
I45.9 Conduction disorder, unspecified
0.000 0.678 0.322
I28 Other diseases of pulmonary vessels
0.000 0.682 0.317
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.689 0.311
I45.5 Other specified heart block
0.000 0.695 0.305
I45.8 Other specified conduction disorders
0.000 0.698 0.302
I45.4 Nonspecific intraventricular block
0.000 0.698 0.302
I45.0 Right fascicular block
0.000 0.698 0.302
I42.6 Alcoholic cardiomyopathy
0.001 0.707 0.292
I45.2 Bifascicular block
0.000 0.728 0.272
I45.6 Preexcitation syndrome
0.000 0.730 0.269
I42.2 Other hypertrophic cardiomyopathy
0.001 0.731 0.268
I26 Pulmonary embolism
0.000 0.733 0.266
I45.3 Trifascicular block
0.000 0.750 0.249
I95-I99 Other and unspecified disorders of the circulatory system
0.001 0.752 0.248
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.772 0.228
I28.8 Other specified diseases of pulmonary vessels
0.000 0.772 0.228
I28.1 Aneurysm of pulmonary artery
0.000 0.772 0.228
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.772 0.228
I44.0 Atrioventricular block, first degree
0.000 0.781 0.219
E70-E90 Metabolic disorders
0.000 0.794 0.206
I45.1 Other and unspecified right bundle-branch block
0.000 0.801 0.199
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.809 0.191
I98 Other disorders of circulatory system in diseases classified elsewhere
0.001 0.828 0.171
E83 Disorders of mineral metabolism
0.000 0.836 0.164
I27 Other pulmonary heart diseases
0.001 0.840 0.159
I42.0 Dilated cardiomyopathy
0.001 0.842 0.157
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.844 0.156
I99 Other and unspecified disorders of circulatory system
0.001 0.849 0.150
E50-E64 Other nutritional deficiencies
0.000 0.851 0.149
E85 Amyloidosis
0.000 0.852 0.148
E84 Cystic fibrosis
0.000 0.852 0.148
E79 Disorders of purine and pyrimidine metabolism
0.000 0.852 0.148
E77 Disorders of glycoprotein metabolism
0.000 0.852 0.148
E76 Disorders of glycosaminoglycan metabolism
0.000 0.852 0.148
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.852 0.148
E73 Lactose intolerance
0.000 0.852 0.148
E72 Other disorders of amino-acid metabolism
0.000 0.852 0.148
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.852 0.148
E70 Disorders of aromatic amino-acid metabolism
0.000 0.852 0.148
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.852 0.148
E88 Other metabolic disorders
0.000 0.857 0.143
E83.5 Disorders of calcium metabolism
0.000 0.858 0.142
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.860 0.140
E74 Other disorders of carbohydrate metabolism
0.000 0.862 0.138
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.864 0.136
E53 Deficiency of other B group vitamins
0.000 0.864 0.135
E10-E14 Diabetes mellitus
0.000 0.866 0.134
E83.3 Disorders of phosphorus metabolism
0.000 0.868 0.132
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.869 0.131
E00-E07 Disorders of thyroid gland
0.000 0.871 0.129
E53.8 Deficiency of other specified B group vitamins
0.000 0.874 0.126
E55 Vitamin D deficiency
0.000 0.874 0.126
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.001 0.876 0.123
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.876 0.123
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.001 0.876 0.123
I98.0 Cardiovascular syphilis
0.001 0.876 0.123
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.882 0.117
E83.8 Other disorders of mineral metabolism
0.000 0.882 0.117
E83.2 Disorders of zinc metabolism
0.000 0.882 0.117
E83.0 Disorders of copper metabolism
0.000 0.882 0.117
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.883 0.117
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.884 0.115
I27.8 Other specified pulmonary heart diseases
0.001 0.885 0.114
I27.1 Kyphoscoliotic heart disease
0.001 0.885 0.114
E61 Deficiency of other nutrient elements
0.000 0.885 0.114
E10 Insulin-dependent diabetes mellitus
0.000 0.887 0.113
E55.9 Vitamin D deficiency, unspecified
0.000 0.890 0.110
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.891 0.109
E14 Unspecified diabetes mellitus
0.000 0.891 0.109
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.892 0.108
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.892 0.108
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.893 0.107
E63 Other nutritional deficiencies
0.000 0.893 0.107
E56 Other vitamin deficiencies
0.000 0.893 0.107
E51 Thiamine deficiency
0.000 0.893 0.107
E50 Vitamin A deficiency
0.000 0.893 0.107
E60 Dietary zinc deficiency
0.000 0.893 0.107
E59 Dietary selenium deficiency
0.000 0.893 0.107
E58 Dietary calcium deficiency
0.000 0.893 0.107
E54 Ascorbic acid deficiency
0.000 0.893 0.107
E52 Niacin deficiency [pellagra]
0.000 0.893 0.107
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.894 0.106
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.894 0.106
E70.3 Albinism
0.000 0.894 0.106
E70.2 Disorders of tyrosine metabolism
0.000 0.894 0.106
E70.1 Other hyperphenylalaninaemias
0.000 0.894 0.106
E70.0 Classical phenylketonuria
0.000 0.894 0.106
E71.3 Disorders of fatty-acid metabolism
0.000 0.894 0.106
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.894 0.106
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.894 0.106
E71.0 Maple-syrup-urine disease
0.000 0.894 0.106
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.894 0.106
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.894 0.106
E72.5 Disorders of glycine metabolism
0.000 0.894 0.106
E72.4 Disorders of ornithine metabolism
0.000 0.894 0.106
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.894 0.106
E72.2 Disorders of urea cycle metabolism
0.000 0.894 0.106
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.894 0.106
E72.0 Disorders of amino-acid transport
0.000 0.894 0.106
E73.9 Lactose intolerance, unspecified
0.000 0.894 0.106
E73.8 Other lactose intolerance
0.000 0.894 0.106
E73.1 Secondary lactase deficiency
0.000 0.894 0.106
E73.0 Congenital lactase deficiency
0.000 0.894 0.106
E75.6 Lipid storage disorder, unspecified
0.000 0.894 0.106
E75.5 Other lipid storage disorders
0.000 0.894 0.106
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.894 0.106
E75.3 Sphingolipidosis, unspecified
0.000 0.894 0.106
E75.2 Other sphingolipidosis
0.000 0.894 0.106
E75.1 Other gangliosidosis
0.000 0.894 0.106
E75.0 GM2 gangliosidosis
0.000 0.894 0.106
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.894 0.106
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.894 0.106
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.894 0.106
E76.2 Other mucopolysaccharidoses
0.000 0.894 0.106
E76.1 Mucopolysaccharidosis, type II
0.000 0.894 0.106
E76.0 Mucopolysaccharidosis, type I
0.000 0.894 0.106
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.894 0.106
E77.8 Other disorders of glycoprotein metabolism
0.000 0.894 0.106
E77.1 Defects in glycoprotein degradation
0.000 0.894 0.106
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.894 0.106
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.894 0.106
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.894 0.106
E79.1 Lesch-Nyhan syndrome
0.000 0.894 0.106
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.894 0.106
E84.9 Cystic fibrosis, unspecified
0.000 0.894 0.106
E84.8 Cystic fibrosis with other manifestations
0.000 0.894 0.106
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.894 0.106
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.894 0.106
E85.9 Amyloidosis, unspecified
0.000 0.894 0.106
E85.8 Other amyloidosis
0.000 0.894 0.106
E85.4 Organ-limited amyloidosis
0.000 0.894 0.106
E85.3 Secondary systemic amyloidosis
0.000 0.894 0.106
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.894 0.106
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.894 0.106
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.894 0.106
E40-E46 Malnutrition
0.000 0.895 0.105
E10.3 With ophthalmic complications
0.000 0.896 0.104
E83.4 Disorders of magnesium metabolism
0.000 0.897 0.103
E88.9 Metabolic disorder, unspecified
0.000 0.897 0.102
E88.8 Other specified metabolic disorders
0.000 0.897 0.102
E88.3 Tumour lysis syndrome
0.000 0.897 0.102
E88.2 Lipomatosis, not elsewhere classified
0.000 0.897 0.102
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.897 0.102
E07 Other disorders of thyroid
0.000 0.897 0.102
E06 Thyroiditis
0.000 0.900 0.099
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.901 0.099
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.901 0.099
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.901 0.099
E74.2 Disorders of galactose metabolism
0.000 0.901 0.099
E74.1 Disorders of fructose metabolism
0.000 0.901 0.099
E74.0 Glycogen storage disease
0.000 0.901 0.099
E04 Other non-toxic goitre
0.000 0.901 0.099
E65-E68 Obesity and other hyperalimentation
0.000 0.901 0.099
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.902 0.098
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.902 0.098
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.902 0.098
Z82.2 Family history of deafness and hearing loss
0.000 0.902 0.098
Z82.1 Family history of blindness and visual loss
0.000 0.902 0.098
I27.0 Primary pulmonary hypertension
0.001 0.902 0.097
E53.9 Vitamin B deficiency, unspecified
0.000 0.903 0.097
E53.1 Pyridoxine deficiency
0.000 0.903 0.097
E53.0 Riboflavin deficiency
0.000 0.903 0.097
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.903 0.097
Z82.3 Family history of stroke
0.000 0.903 0.096
E13 Other specified diabetes mellitus
0.000 0.904 0.096
E12 Malnutrition-related diabetes mellitus
0.000 0.904 0.096
E05.9 Thyrotoxicosis, unspecified
0.000 0.904 0.096
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.905 0.094
E80.6 Other disorders of bilirubin metabolism
0.000 0.905 0.094
E80.5 Crigler-Najjar syndrome
0.000 0.905 0.094
E80.3 Defects of catalase and peroxydase
0.000 0.905 0.094
E80.2 Other porphyria
0.000 0.905 0.094
E80.1 Porphyria cutanea tarda
0.000 0.905 0.094
E80.0 Hereditary erythropoietic porphyria
0.000 0.905 0.094
E87.5 Hyperkalaemia
0.000 0.906 0.094
E14.3 With ophthalmic complications
0.000 0.906 0.094
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.907 0.093
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.907 0.093
E00 Congenital iodine-deficiency syndrome
0.000 0.907 0.093
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.907 0.093
E11 Non-insulin-dependent diabetes mellitus
0.000 0.907 0.093
E83.1 Disorders of iron metabolism
0.000 0.909 0.091
E55.0 Rickets, active
0.000 0.909 0.090
E61.1 Iron deficiency
0.000 0.910 0.090
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.910 0.089

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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