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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4148155
log Bayes Factor = 25.1893
Chromosome 4   position 89,054,667  (GRCh37) Explore rs4148155 on Ensembl!
Variant rs4148155 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M10.99 Gout, unspecified (Site unspecified)
1.000 0.000 0.000
M10.9 Gout, unspecified
1.000 0.000 0.000
M10.97 Gout, unspecified (Ankle and foot)
1.000 0.000 0.000
M10.96 Gout, unspecified (Lower leg)
0.976 0.024 0.000
N20 Calculus of kidney and ureter
0.958 0.042 0.000
N20.1 Calculus of ureter
0.958 0.042 0.000
N20.0 Calculus of kidney
0.942 0.058 0.000
M10 Gout
0.892 0.108 0.000
N20.2 Calculus of kidney with calculus of ureter
0.877 0.123 0.000
N20-N23 Urolithiasis
0.857 0.143 0.000
M10.90 Gout, unspecified (Multiple sites)
0.835 0.165 0.000
M10.94 Gout, unspecified (Hand)
0.805 0.195 0.000
N20.9 Urinary calculus, unspecified
0.801 0.199 0.000
N23 Unspecified renal colic
0.797 0.203 0.000
M10.0 Idiopathic gout
0.780 0.220 0.000
N21 Calculus of lower urinary tract
0.774 0.226 0.000
M10.92 Gout, unspecified (Upper arm)
0.764 0.236 0.000
M10.93 Gout, unspecified (Forearm)
0.761 0.239 0.000
M75.0 Adhesive capsulitis of shoulder
0.758 0.242 0.000
M75 Shoulder lesions
0.752 0.248 0.000
M75.1 Rotator cuff syndrome
0.737 0.263 0.000
M05-M14 Inflammatory polyarthropathies
0.720 0.280 0.000
M10.98 Gout, unspecified (Other)
0.717 0.283 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.717 0.283 0.000
M10.91 Gout, unspecified (Shoulder region)
0.717 0.283 0.000
M70-M79 Other soft tissue disorders
0.708 0.292 0.000
M75.5 Bursitis of shoulder
0.707 0.293 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.701 0.299 0.000
N21.0 Calculus in bladder
0.694 0.306 0.000
M10.00 Idiopathic gout (Multiple sites)
0.671 0.329 0.000
M80-M85 Disorders of bone density and structure
0.665 0.335 0.000
M10.4 Other secondary gout
0.640 0.360 0.000
M10.3 Gout due to impairment of renal function
0.640 0.360 0.000
M10.2 Drug-induced gout
0.640 0.360 0.000
M10.1 Lead-induced gout
0.640 0.360 0.000
M91-M94 Chondropathies
0.640 0.360 0.000
N21.8 Other lower urinary tract calculus
0.627 0.373 0.000
M40-M43 Deforming dorsopathies
0.621 0.379 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.616 0.384 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.614 0.385 0.000
M85 Other disorders of bone density and structure
0.594 0.406 0.000
M41 Scoliosis
0.592 0.408 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.586 0.414 0.000
M00-M03 Infectious arthropathies
0.580 0.420 0.000
M12 Other specific arthropathies
0.578 0.422 0.000
M76 Enthesopathies of lower limb, excluding foot
0.576 0.424 0.000
M41.9 Scoliosis, unspecified
0.563 0.437 0.000
M82 Osteoporosis in diseases classified elsewhere
0.560 0.439 0.000
M10.09 Idiopathic gout (Site unspecified)
0.559 0.441 0.000
M10.08 Idiopathic gout (Other)
0.559 0.441 0.000
M10.06 Idiopathic gout (Lower leg)
0.559 0.441 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.559 0.441 0.000
M10.04 Idiopathic gout (Hand)
0.559 0.441 0.000
M10.03 Idiopathic gout (Forearm)
0.559 0.441 0.000
M10.02 Idiopathic gout (Upper arm)
0.559 0.441 0.000
M10.01 Idiopathic gout (Shoulder region)
0.559 0.441 0.000
M80 Osteoporosis with pathological fracture
0.557 0.443 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.555 0.445 0.000
M94 Other disorders of cartilage
0.552 0.448 0.000
M75.8 Other shoulder lesions
0.539 0.460 0.000
M85.8 Other specified disorders of bone density and structure
0.538 0.462 0.000
M14 Arthropathies in other diseases classified elsewhere
0.535 0.465 0.000
N21.1 Calculus in urethra
0.533 0.466 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.533 0.467 0.000
M92 Other juvenile osteochondrosis
0.530 0.470 0.000
M86-M90 Other osteopathies
0.529 0.471 0.000
M81 Osteoporosis without pathological fracture
0.523 0.477 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.516 0.484 0.000
M08 Juvenile arthritis
0.516 0.484 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.508 0.492 0.000
M75.2 Bicipital tendinitis
0.500 0.500 0.000
M00 Pyogenic arthritis
0.493 0.506 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.492 0.508 0.000
M93 Other osteochondropathies
0.491 0.508 0.000
M70.4 Prepatellar bursitis
0.490 0.510 0.000
M82.1 Osteoporosis in endocrine disorders
0.486 0.514 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.485 0.515 0.000
M05 Seropositive rheumatoid arthritis
0.485 0.515 0.000
M85.6 Other cyst of bone
0.484 0.516 0.000
M83 Adult osteomalacia
0.477 0.523 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.474 0.526 0.000
M41.5 Other secondary scoliosis
0.471 0.529 0.000
M92.6 Juvenile osteochondrosis of tarsus
0.469 0.531 0.000
M07 Psoriatic and enteropathic arthropathies
0.467 0.532 0.000
M60-M63 Disorders of muscles
0.466 0.534 0.000
M70.2 Olecranon bursitis
0.464 0.535 0.000
M11 Other crystal arthropathies
0.461 0.539 0.000
M75.3 Calcific tendinitis of shoulder
0.459 0.541 0.000
M10.19 Lead-induced gout (Site unspecified)
0.459 0.541 0.000
M10.18 Lead-induced gout (Other)
0.459 0.541 0.000
M10.17 Lead-induced gout (Ankle and foot)
0.459 0.541 0.000
M10.16 Lead-induced gout (Lower leg)
0.459 0.541 0.000
M10.15 Lead-induced gout (Pelvic region and thigh)
0.459 0.541 0.000
M10.14 Lead-induced gout (Hand)
0.459 0.541 0.000
M10.13 Lead-induced gout (Forearm)
0.459 0.541 0.000
M10.12 Lead-induced gout (Upper arm)
0.459 0.541 0.000
M10.11 Lead-induced gout (Shoulder region)
0.459 0.541 0.000
M10.10 Lead-induced gout (Multiple sites)
0.459 0.541 0.000
M10.29 Drug-induced gout (Site unspecified)
0.459 0.541 0.000
M10.28 Drug-induced gout (Other)
0.459 0.541 0.000
M10.27 Drug-induced gout (Ankle and foot)
0.459 0.541 0.000
M10.26 Drug-induced gout (Lower leg)
0.459 0.541 0.000
M10.25 Drug-induced gout (Pelvic region and thigh)
0.459 0.541 0.000
M10.24 Drug-induced gout (Hand)
0.459 0.541 0.000
M10.23 Drug-induced gout (Forearm)
0.459 0.541 0.000
M10.22 Drug-induced gout (Upper arm)
0.459 0.541 0.000
M10.21 Drug-induced gout (Shoulder region)
0.459 0.541 0.000
M10.20 Drug-induced gout (Multiple sites)
0.459 0.541 0.000
M10.39 Gout due to impairment of renal function (Site unspecified)
0.459 0.541 0.000
M10.38 Gout due to impairment of renal function (Other)
0.459 0.541 0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.459 0.541 0.000
M10.36 Gout due to impairment of renal function (Lower leg)
0.459 0.541 0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.459 0.541 0.000
M10.34 Gout due to impairment of renal function (Hand)
0.459 0.541 0.000
M10.33 Gout due to impairment of renal function (Forearm)
0.459 0.541 0.000
M10.32 Gout due to impairment of renal function (Upper arm)
0.459 0.541 0.000
M10.31 Gout due to impairment of renal function (Shoulder region)
0.459 0.541 0.000
M10.30 Gout due to impairment of renal function (Multiple sites)
0.459 0.541 0.000
M10.49 Other secondary gout (Site unspecified)
0.459 0.541 0.000
M10.48 Other secondary gout (Other)
0.459 0.541 0.000
M10.47 Other secondary gout (Ankle and foot)
0.459 0.541 0.000
M10.46 Other secondary gout (Lower leg)
0.459 0.541 0.000
M10.45 Other secondary gout (Pelvic region and thigh)
0.459 0.541 0.000
M10.44 Other secondary gout (Hand)
0.459 0.541 0.000
M10.43 Other secondary gout (Forearm)
0.459 0.541 0.000
M10.42 Other secondary gout (Upper arm)
0.459 0.541 0.000
M10.41 Other secondary gout (Shoulder region)
0.459 0.541 0.000
M10.40 Other secondary gout (Multiple sites)
0.459 0.541 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.459 0.541 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.458 0.542 0.000
M12.2 Villonodular synovitis (pigmented)
0.458 0.542 0.000
M81.4 Drug-induced osteoporosis
0.455 0.545 0.000
M94.2 Chondromalacia
0.452 0.548 0.000
M71 Other bursopathies
0.451 0.549 0.000
M70.7 Other bursitis of hip
0.448 0.552 0.000
M42 Spinal osteochondrosis
0.445 0.555 0.000
M40 Kyphosis and lordosis
0.444 0.556 0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere
0.441 0.559 0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]
0.441 0.559 0.000
M12.3 Palindromic rheumatism
0.441 0.559 0.000
M94.8 Other specified disorders of cartilage
0.436 0.564 0.000
M00.9 Pyogenic arthritis, unspecified
0.432 0.568 0.000
M77 Other enthesopathies
0.431 0.569 0.000
M76.87 Other enthesopathies of lower limb, excluding foot (Ankle and foot)
0.431 0.569 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.430 0.570 0.000
M70.5 Other bursitis of knee
0.429 0.571 0.000
M85.9 Disorder of bone density and structure, unspecified
0.426 0.574 0.000
M85.5 Aneurysmal bone cyst
0.426 0.574 0.000
M85.4 Solitary bone cyst
0.426 0.574 0.000
M85.3 Osteitis condensans
0.426 0.574 0.000
M85.2 Hyperostosis of skull
0.426 0.574 0.000
M85.1 Skeletal fluorosis
0.426 0.574 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.425 0.575 0.000
M41.8 Other forms of scoliosis
0.424 0.576 0.000
M41.4 Neuromuscular scoliosis
0.424 0.576 0.000
M41.3 Thoracogenic scoliosis
0.424 0.576 0.000
M41.2 Other idiopathic scoliosis
0.424 0.576 0.000
M41.1 Juvenile idiopathic scoliosis
0.424 0.576 0.000
M41.0 Infantile idiopathic scoliosis
0.424 0.576 0.000
M86 Osteomyelitis
0.422 0.578 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.421 0.579 0.000
M94.9 Disorder of cartilage, unspecified
0.420 0.580 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.420 0.580 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.420 0.580 0.000
M70.3 Other bursitis of elbow
0.420 0.580 0.000
M70.1 Bursitis of hand
0.420 0.580 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.420 0.580 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.419 0.581 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.417 0.582 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.416 0.584 0.000
M02 Reactive arthropathies
0.416 0.584 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.416 0.584 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.415 0.585 0.000
M12.5 Traumatic arthropathy
0.415 0.585 0.000
M12.4 Intermittent hydrarthrosis
0.415 0.585 0.000
M12.1 Kaschin-Beck disease
0.415 0.585 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.415 0.585 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.414 0.586 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.414 0.586 0.000
M76.9 Enthesopathy of lower limb, unspecified
0.413 0.587 0.000
M76.7 Peroneal tendinitis
0.413 0.587 0.000
M76.5 Patellar tendinitis
0.413 0.587 0.000
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]
0.413 0.587 0.000
M76.3 Iliotibial band syndrome
0.413 0.587 0.000
M76.2 Iliac crest spur
0.413 0.587 0.000
M76.1 Psoas tendinitis
0.413 0.587 0.000
M76.0 Gluteal tendinitis
0.413 0.587 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.412 0.588 0.000
M85.64 Other cyst of bone (Hand)
0.410 0.590 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.407 0.593 0.000
M88 Paget's disease of bone [osteitis deformans]
0.405 0.595 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.404 0.596 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.404 0.596 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.404 0.596 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.404 0.596 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.404 0.596 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.404 0.596 0.000
M14.6 Neuropathic arthropathy
0.402 0.597 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.402 0.598 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.402 0.598 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.402 0.598 0.000
M81.0 Postmenopausal osteoporosis
0.402 0.598 0.000
M80.8 Other osteoporosis with pathological fracture
0.400 0.600 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.400 0.600 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.400 0.600 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.400 0.600 0.000
M94.3 Chondrolysis
0.396 0.604 0.000
M94.1 Relapsing polychondritis
0.396 0.604 0.000
M94.0 Chondrocostal junction syndrome [Tietze]
0.396 0.604 0.000
M76.6 Achilles tendinitis
0.392 0.607 0.000
M75.81 Other shoulder lesions, right shoulder
0.387 0.613 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.385 0.614 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.385 0.614 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.385 0.614 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.385 0.614 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.385 0.614 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.385 0.614 0.000
M93.9 Osteochondropathy, unspecified
0.385 0.615 0.000
M41.56 Other secondary scoliosis (Lumbar region)
0.384 0.616 0.000
M87 Osteonecrosis
0.384 0.616 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.383 0.616 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.383 0.616 0.000
M14.4 Arthropathy in amyloidosis
0.383 0.616 0.000
M14.3 Lipoid dermatoarthritis
0.383 0.616 0.000
M14.2 Diabetic arthropathy
0.383 0.616 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.383 0.616 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.383 0.616 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.383 0.617 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.382 0.618 0.000
M92.5 Juvenile osteochondrosis of tibia and fibula
0.380 0.620 0.000
M92.1 Juvenile osteochondrosis of radius and ulna
0.380 0.620 0.000
M92.9 Juvenile osteochondrosis, unspecified
0.380 0.620 0.000
M92.8 Other specified juvenile osteochondrosis
0.380 0.620 0.000
M92.4 Juvenile osteochondrosis of patella
0.380 0.620 0.000
M92.3 Other juvenile osteochondrosis of upper limb
0.380 0.620 0.000
M92.2 Juvenile osteochondrosis of hand
0.380 0.620 0.000
M92.0 Juvenile osteochondrosis of humerus
0.380 0.620 0.000
M94.26 Chondromalacia (Lower leg)
0.380 0.620 0.000
M70.22 Olecranon bursitis-Upper arm
0.377 0.622 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.377 0.623 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.377 0.623 0.000
M81.8 Other osteoporosis
0.375 0.625 0.000
M81.6 Localised osteoporosis [Lequesne]
0.375 0.625 0.000
M81.5 Idiopathic osteoporosis
0.375 0.625 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.375 0.625 0.000
M81.2 Osteoporosis of disuse
0.375 0.625 0.000
M81.1 Postoophorectomy osteoporosis
0.375 0.625 0.000
M84 Disorders of continuity of bone
0.374 0.626 0.000
M12.24 Villonodular synovitis (pigmented) (Hand)
0.371 0.629 0.000
M72 Fibroblastic disorders
0.371 0.629 0.000
M08.9 Juvenile arthritis, unspecified
0.370 0.630 0.000
M08.8 Other juvenile arthritis
0.370 0.630 0.000
M08.4 Pauciarticular juvenile arthritis
0.370 0.630 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.370 0.630 0.000
M08.2 Juvenile arthritis with systemic onset
0.370 0.630 0.000
M08.1 Juvenile ankylosing spondylitis
0.370 0.630 0.000
M08.0 Juvenile rheumatoid arthritis
0.370 0.630 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.370 0.630 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.370 0.630 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.370 0.630 0.000
M09.0 Juvenile arthritis in psoriasis
0.370 0.630 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.369 0.631 0.000
M85.0 Fibrous dysplasia (monostotic)
0.368 0.632 0.000
M73.8 Other soft tissue disorders in diseases classified elsewhere
0.364 0.636 0.000
M73.1 Syphilitic bursitis
0.364 0.636 0.000
M73.0 Gonococcal bursitis
0.364 0.636 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.363 0.637 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.361 0.639 0.000
M75.9 Shoulder lesion, unspecified
0.360 0.639 0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)
0.357 0.642 0.000
M89 Other disorders of bone
0.357 0.643 0.000
M76.86 Other enthesopathies of lower limb, excluding foot (Lower leg)
0.356 0.644 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.355 0.645 0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents
0.354 0.646 0.000
M00.2 Other streptococcal arthritis and polyarthritis
0.354 0.646 0.000
M00.1 Pneumococcal arthritis and polyarthritis
0.354 0.646 0.000
M00.0 Staphylococcal arthritis and polyarthritis
0.354 0.646 0.000
M76.89 Other enthesopathies of lower limb, excluding foot-Site uns
0.353 0.647 0.000
M76.88 Other enthesopathies of lower limb, excluding foot-Other
0.353 0.647 0.000
M76.85 Other enthesopathies of lower limb, excluding foot (Pelvic region and thigh)
0.353 0.647 0.000
M76.84 Other enthesopathies of lower limb, excluding foot-Hand
0.353 0.647 0.000
M76.83 Other enthesopathies of lower limb, excluding foot-Forearm
0.353 0.647 0.000
M76.82 Other enthesopathies of lower limb, excluding foot-Upper ar
0.353 0.647 0.000
M76.81 Other enthesopathies of lower limb, excluding foot-Shldr re
0.353 0.647 0.000
M76.80 Other enthesopathies of lower limb, excluding foot (Multiple sites)
0.353 0.647 0.000
M93.8 Other specified osteochondropathies
0.352 0.647 0.000
M93.2 Osteochondritis dissecans
0.352 0.647 0.000
M93.1 Kienbock's disease of adults
0.352 0.647 0.000
M93.0 Slipped upper femoral epiphysis (nontraumatic)
0.352 0.647 0.000
M70.49 Prepatellar bursitis-Site unspec
0.351 0.649 0.000
M70.48 Prepatellar bursitis-Other
0.351 0.649 0.000
M70.47 Prepatellar bursitis-Ankle/Foot
0.351 0.649 0.000
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.351 0.649 0.000
M70.44 Prepatellar bursitis-Hand
0.351 0.649 0.000
M70.43 Prepatellar bursitis-Forearm
0.351 0.649 0.000
M70.42 Prepatellar bursitis-Upper arm
0.351 0.649 0.000
M70.41 Prepatellar bursitis-Shldr region
0.351 0.649 0.000
M70.40 Prepatellar bursitis-Mult sites
0.351 0.649 0.000
M70.75 Other bursitis of hip-Pelvic/Thigh
0.350 0.650 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.349 0.651 0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)
0.348 0.651 0.000
M82.18 Osteoporosis in endocrine disorders (Other)
0.348 0.651 0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)
0.348 0.651 0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)
0.348 0.651 0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)
0.348 0.651 0.000
M82.14 Osteoporosis in endocrine disorders (Hand)
0.348 0.651 0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)
0.348 0.651 0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)
0.348 0.651 0.000
M05.8 Other seropositive rheumatoid arthritis
0.348 0.652 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.348 0.652 0.000
M05.2 Rheumatoid vasculitis
0.348 0.652 0.000
M05.1 Rheumatoid lung disease
0.348 0.652 0.000
M05.0 Felty's syndrome
0.348 0.652 0.000
M85.69 Other cyst of bone (Site unspecified)
0.347 0.653 0.000
M85.68 Other cyst of bone (Other)
0.347 0.653 0.000
M85.66 Other cyst of bone (Lower leg)
0.347 0.653 0.000
M85.63 Other cyst of bone (Forearm)
0.347 0.653 0.000
M85.62 Other cyst of bone (Upper arm)
0.347 0.653 0.000
M85.61 Other cyst of bone (Shoulder region)
0.347 0.653 0.000
M85.60 Other cyst of bone (Multiple sites)
0.347 0.653 0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)
0.345 0.655 0.000
M94.88 Other specified disorders of cartilage (Other)
0.345 0.655 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.342 0.658 0.000
M83.9 Adult osteomalacia, unspecified
0.342 0.658 0.000
M83.8 Other adult osteomalacia
0.342 0.658 0.000
M83.5 Other drug-induced osteomalacia in adults
0.342 0.658 0.000
M83.4 Aluminum bone disease
0.342 0.658 0.000
M83.3 Adult osteomalacia due to malnutrition
0.342 0.658 0.000
M83.2 Adult osteomalacia due to malabsorption
0.342 0.658 0.000
M83.1 Senile osteomalacia
0.342 0.658 0.000
M83.0 Puerperal osteomalacia
0.342 0.658 0.000
M90 Osteopathies in diseases classified elsewhere
0.341 0.659 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.340 0.660 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.340 0.660 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.340 0.660 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.340 0.660 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.340 0.660 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.340 0.660 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.340 0.660 0.000
M92.7 Juvenile osteochondrosis of metatarsus
0.338 0.662 0.000
M41.59 Other secondary scoliosis (Site unspecified)
0.338 0.662 0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)
0.338 0.662 0.000
M41.57 Other secondary scoliosis (Lumbosacral region)
0.338 0.662 0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)
0.338 0.662 0.000
M41.54 Other secondary scoliosis (Thoracic region)
0.338 0.662 0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)
0.338 0.662 0.000
M41.52 Other secondary scoliosis (Cervical region)
0.338 0.662 0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)
0.338 0.662 0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)
0.338 0.662 0.000
M60 Myositis
0.336 0.664 0.000
M07.6 Other enteropathic arthropathies
0.335 0.665 0.000
M07.5 Arthropathy in ulcerative colitis
0.335 0.665 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.335 0.665 0.000
M07.2 Psoriatic spondylitis
0.335 0.665 0.000
M07.1 Arthritis mutilans
0.335 0.665 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.335 0.665 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.334 0.665 0.000
M61 Calcification and ossification of muscle
0.334 0.665 0.000
M70.29 Olecranon bursitis-Site unspec
0.333 0.667 0.000
M70.28 Olecranon bursitis-Other
0.333 0.667 0.000
M70.27 Olecranon bursitis-Ankle/Foot
0.333 0.667 0.000
M70.26 Olecranon bursitis-Lower Leg
0.333 0.667 0.000
M70.25 Olecranon bursitis-Pelvic/Thigh
0.333 0.667 0.000
M70.24 Olecranon bursitis-Hand
0.333 0.667 0.000
M70.23 Olecranon bursitis-Forearm
0.333 0.667 0.000
M70.21 Olecranon bursitis-Shldr region
0.333 0.667 0.000
M70.20 Olecranon bursitis-Mult sites
0.333 0.667 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.333 0.667 0.000
M11.9 Crystal arthropathy, unspecified
0.330 0.669 0.000
M11.8 Other specified crystal arthropathies
0.330 0.669 0.000
M11.1 Familial chondrocalcinosis
0.330 0.669 0.000
M11.0 Hydroxyapatite deposition disease
0.330 0.669 0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)
0.330 0.670 0.000
M91.9 Juvenile osteochondrosis of hip and pelvis, unspecified
0.329 0.671 0.000
M91.8 Other juvenile osteochondrosis of hip and pelvis
0.329 0.671 0.000
M91.3 Pseudocoxalgia
0.329 0.671 0.000
M91.2 Coxa plana
0.329 0.671 0.000
M91.1 Juvenile osteochondrosis of head of femur [Legg-Calve-Perthes]
0.329 0.671 0.000
M91.0 Juvenile osteochondrosis of pelvis
0.329 0.671 0.000
M86.6 Other chronic osteomyelitis
0.329 0.671 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.329 0.671 0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.328 0.672 0.000
M12.28 Villonodular synovitis (pigmented) (Other)
0.328 0.672 0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.328 0.672 0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.328 0.672 0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.328 0.672 0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.328 0.672 0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.328 0.672 0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.328 0.672 0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.328 0.672 0.000
M81.48 Drug-induced osteoporosis (Other)
0.327 0.673 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.327 0.673 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.327 0.673 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.327 0.673 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.327 0.673 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.327 0.673 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.327 0.673 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.327 0.673 0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)
0.326 0.674 0.000
M86.9 Osteomyelitis, unspecified
0.324 0.676 0.000
M70.6 Trochanteric bursitis
0.324 0.676 0.000
M94.29 Chondromalacia (Site unspecified)
0.324 0.676 0.000
M94.28 Chondromalacia (Other)
0.324 0.676 0.000
M94.27 Chondromalacia (Ankle and foot)
0.324 0.676 0.000
M94.25 Chondromalacia (Pelvic region and thigh)
0.324 0.676 0.000
M94.24 Chondromalacia (Hand)
0.324 0.676 0.000
M94.23 Chondromalacia (Forearm)
0.324 0.676 0.000
M94.22 Chondromalacia (Upper arm)
0.324 0.676 0.000
M94.21 Chondromalacia (Shoulder region)
0.324 0.676 0.000
M94.20 Chondromalacia (Multiple sites)
0.324 0.676 0.000
M71.9 Bursopathy, unspecified
0.323 0.676 0.000
M71.8 Other specified bursopathies
0.323 0.676 0.000
M71.5 Other bursitis, not elsewhere classified
0.323 0.676 0.000
M71.4 Calcium deposit in bursa
0.323 0.676 0.000
M71.1 Other infective bursitis
0.323 0.676 0.000
M71.0 Abscess of bursa
0.323 0.676 0.000
M77.5 Other enthesopathy of foot
0.324 0.676 0.000
M70.79 Other bursitis of hip-Site unspec
0.321 0.678 0.000
M70.78 Other bursitis of hip-Other
0.321 0.678 0.000
M70.77 Other bursitis of hip-Ankle/Foot
0.321 0.678 0.000
M70.76 Other bursitis of hip-Lower Leg
0.321 0.678 0.000
M70.74 Other bursitis of hip-Hand
0.321 0.678 0.000
M70.73 Other bursitis of hip-Forearm
0.321 0.678 0.000
M70.72 Other bursitis of hip-Upper arm
0.321 0.678 0.000
M70.71 Other bursitis of hip-Shldr region
0.321 0.678 0.000
M70.70 Other bursitis of hip-Mult sites
0.321 0.678 0.000
M42.9 Spinal osteochondrosis, unspecified
0.319 0.681 0.000
M42.1 Adult osteochondrosis of spine
0.319 0.681 0.000
M42.0 Juvenile osteochondrosis of spine
0.319 0.681 0.000
M40.5 Lordosis, unspecified
0.318 0.682 0.000
M40.4 Other lordosis
0.318 0.682 0.000
M40.3 Flatback syndrome
0.318 0.682 0.000
M40.1 Other secondary kyphosis
0.318 0.682 0.000
M40.0 Postural kyphosis
0.318 0.682 0.000
M71.3 Other bursal cyst
0.318 0.682 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.317 0.683 0.000
M40.2 Other and unspecified kyphosis
0.317 0.683 0.000
M88.9 Paget's disease of bone, unspecified
0.317 0.683 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.316 0.684 0.000
M12.38 Palindromic rheumatism (Other)
0.316 0.684 0.000
M12.37 Palindromic rheumatism (Ankle and foot)
0.316 0.684 0.000
M12.36 Palindromic rheumatism (Lower leg)
0.316 0.684 0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.316 0.684 0.000
M12.34 Palindromic rheumatism (Hand)
0.316 0.684 0.000
M12.33 Palindromic rheumatism (Forearm)
0.316 0.684 0.000
M12.32 Palindromic rheumatism (Upper arm)
0.316 0.684 0.000
M12.31 Palindromic rheumatism (Shoulder region)
0.316 0.684 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.316 0.684 0.000
M70.56 Other bursitis of knee-Lower Leg
0.316 0.684 0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)
0.315 0.685 0.000
M94.89 Other specified disorders of cartilage (Site unspecified)
0.312 0.687 0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)
0.312 0.687 0.000
M94.84 Other specified disorders of cartilage (Hand)
0.312 0.687 0.000
M94.83 Other specified disorders of cartilage (Forearm)
0.312 0.687 0.000
M94.82 Other specified disorders of cartilage (Upper arm)
0.312 0.687 0.000
M94.81 Other specified disorders of cartilage (Shoulder region)
0.312 0.687 0.000
M94.80 Other specified disorders of cartilage (Multiple sites)
0.312 0.687 0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)
0.310 0.690 0.000
M00.98 Pyogenic arthritis, unspecified (Other)
0.310 0.690 0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)
0.310 0.690 0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)
0.310 0.690 0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)
0.310 0.690 0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)
0.310 0.690 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.309 0.690 0.000
M77.3 Calcaneal spur
0.309 0.690 0.000
M77.2 Periarthritis of wrist
0.309 0.690 0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.308 0.692 0.000
M70.59 Other bursitis of knee-Site unspec
0.307 0.692 0.000
M70.58 Other bursitis of knee-Other
0.307 0.692 0.000
M70.57 Other bursitis of knee-Ankle/Foot
0.307 0.692 0.000
M70.55 Other bursitis of knee-Pelvic/Thigh
0.307 0.692 0.000
M70.54 Other bursitis of knee-Hand
0.307 0.692 0.000
M70.53 Other bursitis of knee-Forearm
0.307 0.692 0.000
M70.52 Other bursitis of knee-Upper arm
0.307 0.692 0.000
M70.51 Other bursitis of knee-Shldr region
0.307 0.692 0.000
M70.50 Other bursitis of knee-Mult sites
0.307 0.692 0.000
M85.19 Skeletal fluorosis (Site unspecified)
0.306 0.694 0.000
M85.18 Skeletal fluorosis (Other)
0.306 0.694 0.000
M85.17 Skeletal fluorosis (Ankle and foot)
0.306 0.694 0.000
M85.16 Skeletal fluorosis (Lower leg)
0.306 0.694 0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)
0.306 0.694 0.000
M85.14 Skeletal fluorosis (Hand)
0.306 0.694 0.000
M85.13 Skeletal fluorosis (Forearm)
0.306 0.694 0.000
M85.12 Skeletal fluorosis (Upper arm)
0.306 0.694 0.000
M85.11 Skeletal fluorosis (Shoulder region)
0.306 0.694 0.000
M85.10 Skeletal fluorosis (Multiple sites)
0.306 0.694 0.000
M85.29 Hyperostosis of skull-Site unspec
0.306 0.694 0.000
M85.28 Hyperostosis of skull-Other
0.306 0.694 0.000
M85.27 Hyperostosis of skull-Ankle/Foot
0.306 0.694 0.000
M85.26 Hyperostosis of skull-Lower Leg
0.306 0.694 0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh
0.306 0.694 0.000
M85.24 Hyperostosis of skull-Hand
0.306 0.694 0.000
M85.23 Hyperostosis of skull-Forearm
0.306 0.694 0.000
M85.22 Hyperostosis of skull-Upper arm
0.306 0.694 0.000
M85.21 Hyperostosis of skull-Shldr region
0.306 0.694 0.000
M85.20 Hyperostosis of skull-Mult sites
0.306 0.694 0.000
M85.39 Osteitis condensans (Site unspecified)
0.306 0.694 0.000
M85.38 Osteitis condensans (Other)
0.306 0.694 0.000
M85.37 Osteitis condensans (Ankle and foot)
0.306 0.694 0.000
M85.36 Osteitis condensans (Lower leg)
0.306 0.694 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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