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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4148218
log Bayes Factor = 14.1783
Chromosome 2   position 44,099,582  (GRCh37) Explore rs4148218 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80.1 Calculus of gallbladder with other cholecystitis
1.000 0.000 0.000
K80 Cholelithiasis
1.000 0.000 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K80.2 Calculus of gallbladder without cholecystitis
1.000 0.000 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.999 0.001 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.022 0.978
K80.0 Calculus of gallbladder with acute cholecystitis
0.969 0.031 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.035 0.965
E78.2 Mixed hyperlipidaemia
0.000 0.096 0.904
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.119 0.881
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.211 0.789
I25 Chronic ischaemic heart disease
0.000 0.215 0.785
I25.1 Atherosclerotic heart disease
0.000 0.219 0.781
K80.4 Calculus of bile duct with cholecystitis
0.758 0.242 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.275 0.725
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.281 0.719
K80.3 Calculus of bile duct with cholangitis
0.717 0.283 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.286 0.714
E78.6 Lipoprotein deficiency
0.000 0.298 0.701
E78.3 Hyperchylomicronaemia
0.000 0.298 0.701
E78.4 Other hyperlipidaemia
0.000 0.347 0.653
I25.3 Aneurysm of heart
0.000 0.347 0.653
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.351 0.649
I25.2 Old myocardial infarction
0.000 0.356 0.644
I25.6 Silent myocardial ischaemia
0.000 0.437 0.563
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.444 0.556
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.514 0.486 0.000
I25.4 Coronary artery aneurysm
0.000 0.518 0.481
K80.8 Other cholelithiasis
0.441 0.559 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.402 0.598 0.000
K82 Other diseases of gallbladder
0.388 0.612 0.000
K82.8 Other specified diseases of gallbladder
0.378 0.622 0.000
I20-I25 Ischaemic heart diseases
0.000 0.624 0.376
K81 Cholecystitis
0.344 0.656 0.000
I22 Subsequent myocardial infarction
0.000 0.664 0.336
K81.1 Chronic cholecystitis
0.302 0.698 0.000
K82.3 Fistula of gallbladder
0.297 0.703 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.708 0.291
K82.2 Perforation of gallbladder
0.290 0.710 0.000
K82.4 Cholesterolosis of gallbladder
0.290 0.710 0.000
K81.9 Cholecystitis, unspecified
0.290 0.710 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.288 0.712 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.712 0.288
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.713 0.287
K82.1 Hydrops of gallbladder
0.286 0.714 0.000
K81.8 Other cholecystitis
0.263 0.737 0.000
I23 Certain current complications following acute myocardial infarction
0.000 0.741 0.259
I22.8 Subsequent myocardial infarction of other sites
0.000 0.742 0.258
I20 Angina pectoris
0.000 0.745 0.255
I21 Acute myocardial infarction
0.000 0.745 0.255
K82.0 Obstruction of gallbladder
0.254 0.746 0.000
K82.9 Disease of gallbladder, unspecified
0.245 0.754 0.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.757 0.243
I20.0 Unstable angina
0.000 0.773 0.227
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.775 0.225
K87.1 Disorders of pancreas in diseases classified elsewhere
0.207 0.793 0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.207 0.793 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.796 0.204
K85 Acute pancreatitis
0.201 0.799 0.000
I20.9 Angina pectoris, unspecified
0.000 0.813 0.187
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.814 0.186
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.814 0.186
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.814 0.186
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.814 0.186
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.814 0.186
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.814 0.186
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.814 0.186
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.817 0.183
I23.8 Other current complications following acute myocardial infarction
0.000 0.825 0.175
I24 Other acute ischaemic heart diseases
0.000 0.825 0.175
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.828 0.171
K85.1 Biliary acute pancreatitis
0.160 0.840 0.000
I35 Nonrheumatic aortic valve disorders
0.000 0.849 0.151
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.851 0.149
I35.0 Aortic (valve) stenosis
0.000 0.853 0.147
K85.3 Drug-induced acute pancreatitis
0.144 0.856 0.000
K85.0 Idiopathic acute pancreatitis
0.144 0.856 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.858 0.142
K81.0 Acute cholecystitis
0.137 0.863 0.000
I35.9 Aortic valve disorder, unspecified
0.000 0.866 0.134
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.868 0.132
K85.2 Alcohol-induced acute pancreatitis
0.131 0.868 0.000
I35.1 Aortic (valve) insufficiency
0.000 0.872 0.128
I20.8 Other forms of angina pectoris
0.000 0.872 0.128
I20.1 Angina pectoris with documented spasm
0.000 0.876 0.124
K85.8 Other acute pancreatitis
0.121 0.879 0.000
I24.1 Dressler's syndrome
0.000 0.888 0.112
I35.8 Other aortic valve disorders
0.000 0.888 0.112
I24.8 Other forms of acute ischaemic heart disease
0.000 0.891 0.109
K83 Other diseases of biliary tract
0.102 0.898 0.000
I42 Cardiomyopathy
0.000 0.898 0.102
I42.9 Cardiomyopathy, unspecified
0.000 0.903 0.097
I30-I52 Other forms of heart disease
0.000 0.905 0.095
I38 Endocarditis, valve unspecified
0.000 0.909 0.091
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.910 0.090
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.910 0.090
I42.0 Dilated cardiomyopathy
0.000 0.910 0.090
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.910 0.090
K85.9 Acute pancreatitis, unspecified
0.086 0.914 0.000
Chapter IX Diseases of the circulatory system
0.000 0.915 0.085
I42.6 Alcoholic cardiomyopathy
0.000 0.917 0.083
K83.3 Fistula of bile duct
0.082 0.917 0.000
I42.2 Other hypertrophic cardiomyopathy
0.000 0.918 0.082
I31 Other diseases of pericardium
0.000 0.920 0.080
I51.7 Cardiomegaly
0.000 0.923 0.077
I37 Pulmonary valve disorders
0.000 0.924 0.076
K83.5 Biliary cyst
0.073 0.926 0.000
K83.4 Spasm of sphincter of Oddi
0.073 0.926 0.000
K83.2 Perforation of bile duct
0.073 0.926 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.927 0.073
I42.5 Other restrictive cardiomyopathy
0.000 0.927 0.073
I42.4 Endocardial fibroelastosis
0.000 0.927 0.073
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.927 0.073
I42.8 Other cardiomyopathies
0.000 0.927 0.073
I51 Complications and ill-defined descriptions of heart disease
0.000 0.928 0.072
I31.9 Disease of pericardium, unspecified
0.000 0.931 0.069
I52 Other heart disorders in diseases classified elsewhere
0.000 0.931 0.069
I48 Atrial fibrillation and flutter
0.000 0.931 0.069
I41 Myocarditis in diseases classified elsewhere
0.000 0.931 0.069
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.931 0.069
I32 Pericarditis in diseases classified elsewhere
0.000 0.931 0.069
I33 Acute and subacute endocarditis
0.000 0.933 0.067
I21.4 Acute subendocardial myocardial infarction
0.000 0.933 0.067
Z95.4 Presence of other heart-valve replacement
0.000 0.935 0.065
I30 Acute pericarditis
0.000 0.936 0.064
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.936 0.064
I05-I09 Chronic rheumatic heart diseases
0.000 0.936 0.064
I40 Acute myocarditis
0.000 0.937 0.063
I36 Nonrheumatic tricuspid valve disorders
0.000 0.938 0.062
I37.1 Pulmonary valve insufficiency
0.000 0.938 0.061
K83.9 Disease of biliary tract, unspecified
0.060 0.940 0.000
I00-I02 Acute rheumatic fever
0.000 0.940 0.060
Z95.3 Presence of xenogenic heart valve
0.000 0.940 0.060
I31.0 Chronic adhesive pericarditis
0.000 0.941 0.059
I31.1 Chronic constrictive pericarditis
0.000 0.942 0.058
I31.8 Other specified diseases of pericardium
0.000 0.942 0.057
I31.2 Haemopericardium, not elsewhere classified
0.000 0.942 0.057
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.942 0.058
I51.0 Cardiac septal defect, acquired
0.000 0.944 0.056
I31.3 Pericardial effusion (noninflammatory)
0.000 0.944 0.056
I07 Rheumatic tricuspid valve diseases
0.000 0.945 0.055
I37.9 Pulmonary valve disorder, unspecified
0.000 0.945 0.054
I37.8 Other pulmonary valve disorders
0.000 0.945 0.054
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.945 0.054
I37.0 Pulmonary valve stenosis
0.000 0.945 0.054
I30.1 Infective pericarditis
0.000 0.948 0.052
I33.0 Acute and subacute infective endocarditis
0.000 0.948 0.052
I99 Other and unspecified disorders of circulatory system
0.000 0.948 0.052
I51.5 Myocardial degeneration
0.000 0.948 0.051
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.948 0.051
I46 Cardiac arrest
0.000 0.948 0.052
K83.1 Obstruction of bile duct
0.051 0.949 0.000
K83.8 Other specified diseases of biliary tract
0.050 0.950 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.950 0.050
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.001 0.950 0.049
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.950 0.049
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.950 0.049
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.950 0.049
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.950 0.049
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.950 0.049
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.950 0.049
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.950 0.049
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.950 0.049
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.950 0.049
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.950 0.049
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.950 0.049
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.950 0.049
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.950 0.049
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.950 0.049
I48.4 Atypical atrial flutter
0.000 0.950 0.049
I48.3 Typical atrial flutter
0.000 0.950 0.049
I48.2 Chronic atrial fibrillation
0.000 0.950 0.049
I48.1 Persistent atrial fibrillation
0.000 0.950 0.049
I48.0 Paroxysmal atrial fibrillation
0.000 0.950 0.049
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.950 0.049
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.950 0.049
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.950 0.049
I07.1 Tricuspid insufficiency
0.000 0.951 0.049
I09 Other rheumatic heart diseases
0.000 0.953 0.047
I30.8 Other forms of acute pericarditis
0.000 0.954 0.046
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.954 0.046
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.954 0.046
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.954 0.046
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.954 0.046
I06 Rheumatic aortic valve diseases
0.000 0.954 0.046
I40.9 Acute myocarditis, unspecified
0.000 0.954 0.045
I40.8 Other acute myocarditis
0.000 0.954 0.045
I40.1 Isolated myocarditis
0.000 0.954 0.045
I51.6 Cardiovascular disease, unspecified
0.000 0.955 0.045
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.955 0.045
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.955 0.045
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.955 0.045
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.955 0.045
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.956 0.044
I02 Rheumatic chorea
0.000 0.957 0.043
I01 Rheumatic fever with heart involvement
0.000 0.957 0.043
I00 Rheumatic fever without mention of heart involvement
0.000 0.958 0.042
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.958 0.042
I33.9 Acute endocarditis, unspecified
0.000 0.958 0.042
I08 Multiple valve diseases
0.000 0.959 0.041
I40.0 Infective myocarditis
0.000 0.960 0.040
I07.9 Tricuspid valve disease, unspecified
0.000 0.960 0.040
I07.8 Other tricuspid valve diseases
0.000 0.960 0.040
I07.2 Tricuspid stenosis with insufficiency
0.000 0.960 0.040
I07.0 Tricuspid stenosis
0.000 0.960 0.040
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.960 0.039
I46.9 Cardiac arrest, unspecified
0.000 0.961 0.039
I05 Rheumatic mitral valve diseases
0.000 0.962 0.038
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.962 0.038
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.962 0.038
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.963 0.037
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.963 0.037
I46.1 Sudden cardiac death, so described
0.000 0.963 0.037
Z95.2 Presence of prosthetic heart valve
0.000 0.964 0.036
K83.0 Cholangitis
0.035 0.965 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.965 0.035
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.965 0.034
I09.9 Rheumatic heart disease, unspecified
0.000 0.966 0.034
I09.8 Other specified rheumatic heart diseases
0.000 0.966 0.034
I09.2 Chronic rheumatic pericarditis
0.000 0.966 0.034
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.966 0.034
I09.0 Rheumatic myocarditis
0.000 0.966 0.034
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.967 0.033
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.967 0.033
I06.8 Other rheumatic aortic valve diseases
0.000 0.967 0.033
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.967 0.033
I06.1 Rheumatic aortic insufficiency
0.000 0.967 0.033
I06.0 Rheumatic aortic stenosis
0.000 0.967 0.033
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.968 0.031
I97.0 Postcardiotomy syndrome
0.000 0.968 0.031
I30.9 Acute pericarditis, unspecified
0.000 0.969 0.031
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.969 0.031
I01.8 Other acute rheumatic heart disease
0.000 0.969 0.031
I01.2 Acute rheumatic myocarditis
0.000 0.969 0.031
I01.1 Acute rheumatic endocarditis
0.000 0.969 0.031
I01.0 Acute rheumatic pericarditis
0.000 0.969 0.031
I02.9 Rheumatic chorea without heart involvement
0.000 0.969 0.031
I02.0 Rheumatic chorea with heart involvement
0.000 0.969 0.031
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.969 0.031
I97.1 Other functional disturbances following cardiac surgery
0.000 0.969 0.031
I47 Paroxysmal tachycardia
0.000 0.969 0.031
I08.9 Multiple valve disease, unspecified
0.000 0.970 0.030
I44 Atrioventricular and left bundle-branch block
0.000 0.970 0.030
I10-I15 Hypertensive diseases
0.000 0.971 0.029
I05.9 Mitral valve disease, unspecified
0.000 0.971 0.029
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.972 0.028
I05.0 Mitral stenosis
0.000 0.972 0.028
I05.8 Other mitral valve diseases
0.000 0.972 0.028
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.972 0.027
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.973 0.027
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.973 0.027
I98.0 Cardiovascular syphilis
0.000 0.973 0.027
K66.0 Peritoneal adhesions
0.027 0.973 0.000
I51.4 Myocarditis, unspecified
0.001 0.974 0.026
I47.0 Reentry ventricular arrhythmia
0.000 0.975 0.025
I05.1 Rheumatic mitral insufficiency
0.000 0.976 0.024
I28 Other diseases of pulmonary vessels
0.000 0.976 0.024
I05.2 Mitral stenosis with insufficiency
0.000 0.976 0.023
E70-E90 Metabolic disorders
0.000 0.977 0.023
I08.0 Disorders of both mitral and aortic valves
0.000 0.977 0.023
I44.4 Left anterior fascicular block
0.000 0.977 0.023
I27 Other pulmonary heart diseases
0.000 0.977 0.023
E83.4 Disorders of magnesium metabolism
0.000 0.977 0.023
I51.9 Heart disease, unspecified
0.000 0.977 0.022
I11 Hypertensive heart disease
0.000 0.978 0.022
I44.1 Atrioventricular block, second degree
0.000 0.978 0.022
E83 Disorders of mineral metabolism
0.000 0.978 0.022
I44.5 Left posterior fascicular block
0.000 0.978 0.021
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.979 0.021
K58.9 Irritable bowel syndrome without diarrhoea
0.021 0.979 0.000
I13 Hypertensive heart and renal disease
0.000 0.979 0.021
I15 Secondary hypertension
0.000 0.979 0.021
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.980 0.020
I44.7 Left bundle-branch block, unspecified
0.000 0.980 0.020
I44.6 Other and unspecified fascicular block
0.000 0.981 0.019
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.981 0.019
I26 Pulmonary embolism
0.000 0.981 0.019
I50 Heart failure
0.000 0.982 0.018
I08.8 Other multiple valve diseases
0.000 0.982 0.018
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.982 0.018
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.983 0.017
I28.1 Aneurysm of pulmonary artery
0.000 0.983 0.017
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.983 0.017
I15.9 Seconday hypertension, unspecified
0.000 0.983 0.017
I27.9 Pulmonary heart disease, unspecified
0.000 0.983 0.017
E88 Other metabolic disorders
0.000 0.983 0.017
E84 Cystic fibrosis
0.000 0.983 0.017
E77 Disorders of glycoprotein metabolism
0.000 0.983 0.017
E76 Disorders of glycosaminoglycan metabolism
0.000 0.983 0.017
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.983 0.017
E72 Other disorders of amino-acid metabolism
0.000 0.983 0.017
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.983 0.017
E70 Disorders of aromatic amino-acid metabolism
0.000 0.983 0.017
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.983 0.017
E83.3 Disorders of phosphorus metabolism
0.000 0.983 0.017
E83.5 Disorders of calcium metabolism
0.000 0.983 0.017
I27.1 Kyphoscoliotic heart disease
0.000 0.983 0.016
I27.8 Other specified pulmonary heart diseases
0.000 0.983 0.016
E89.2 Postprocedural hypoparathyroidism
0.000 0.983 0.016
K86 Other diseases of pancreas
0.015 0.984 0.002
I44.3 Other and unspecified atrioventricular block
0.000 0.984 0.016
E79 Disorders of purine and pyrimidine metabolism
0.000 0.984 0.016
I44.0 Atrioventricular block, first degree
0.000 0.984 0.016
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.984 0.016
E83.8 Other disorders of mineral metabolism
0.000 0.984 0.016
E83.2 Disorders of zinc metabolism
0.000 0.984 0.016
E83.0 Disorders of copper metabolism
0.000 0.984 0.016
I46.0 Cardiac arrest with successful resuscitation
0.000 0.984 0.016
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.985 0.015
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.985 0.015
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.985 0.015
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.985 0.015
I15.8 Other secondary hypertension
0.000 0.985 0.015
I15.2 Hypertension secondary to endocrine disorders
0.000 0.985 0.015
I45 Other conduction disorders
0.000 0.985 0.015
I27.2 Other secondary pulmonary hypertension
0.000 0.985 0.015
I12 Hypertensive renal disease
0.000 0.985 0.015
I15.0 Renovascular hypertension
0.000 0.986 0.014
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.986 0.014
I28.8 Other specified diseases of pulmonary vessels
0.000 0.986 0.014
I44.2 Atrioventricular block, complete
0.000 0.986 0.014
E88.2 Lipomatosis, not elsewhere classified
0.000 0.986 0.014
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.986 0.014
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.986 0.014
E74 Other disorders of carbohydrate metabolism
0.000 0.986 0.014
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.986 0.014
I15.1 Hypertension secondary to other renal disorders
0.000 0.987 0.013
I77 Other disorders of arteries and arterioles
0.000 0.987 0.013
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.987 0.013
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.987 0.013
E89.5 Postprocedural testicular hypofunction
0.000 0.987 0.013
E89.4 Postprocedural ovarian failure
0.000 0.987 0.013
E89.1 Postprocedural hypoinsulinaemia
0.000 0.987 0.013
I50.0 Congestive heart failure
0.000 0.987 0.013
E73 Lactose intolerance
0.000 0.987 0.013
I27.0 Primary pulmonary hypertension
0.000 0.987 0.013
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.987 0.013
E89.3 Postprocedural hypopituitarism
0.000 0.987 0.013
I77.1 Stricture of artery
0.000 0.987 0.013
E88.9 Metabolic disorder, unspecified
0.000 0.987 0.012
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.988 0.012
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.988 0.012
E70.3 Albinism
0.000 0.988 0.012
E70.2 Disorders of tyrosine metabolism
0.000 0.988 0.012
E70.1 Other hyperphenylalaninaemias
0.000 0.988 0.012
E70.0 Classical phenylketonuria
0.000 0.988 0.012
E71.3 Disorders of fatty-acid metabolism
0.000 0.988 0.012
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.988 0.012
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.988 0.012
E71.0 Maple-syrup-urine disease
0.000 0.988 0.012
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.988 0.012
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.988 0.012
E72.5 Disorders of glycine metabolism
0.000 0.988 0.012
E72.4 Disorders of ornithine metabolism
0.000 0.988 0.012
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.988 0.012
E72.2 Disorders of urea cycle metabolism
0.000 0.988 0.012
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.988 0.012
E72.0 Disorders of amino-acid transport
0.000 0.988 0.012
E75.6 Lipid storage disorder, unspecified
0.000 0.988 0.012
E75.5 Other lipid storage disorders
0.000 0.988 0.012
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.988 0.012
E75.3 Sphingolipidosis, unspecified
0.000 0.988 0.012
E75.2 Other sphingolipidosis
0.000 0.988 0.012
E75.1 Other gangliosidosis
0.000 0.988 0.012
E75.0 GM2 gangliosidosis
0.000 0.988 0.012
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.988 0.012
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.988 0.012
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.988 0.012
E76.2 Other mucopolysaccharidoses
0.000 0.988 0.012
E76.1 Mucopolysaccharidosis, type II
0.000 0.988 0.012
E76.0 Mucopolysaccharidosis, type I
0.000 0.988 0.012
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.988 0.012
E77.8 Other disorders of glycoprotein metabolism
0.000 0.988 0.012
E77.1 Defects in glycoprotein degradation
0.000 0.988 0.012
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.988 0.012
E84.9 Cystic fibrosis, unspecified
0.000 0.988 0.012
E84.8 Cystic fibrosis with other manifestations
0.000 0.988 0.012
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.988 0.012
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.988 0.012
E88.8 Other specified metabolic disorders
0.000 0.988 0.012
K86.9 Disease of pancreas, unspecified
0.011 0.988 0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.988 0.012
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.988 0.012
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.988 0.012
E79.1 Lesch-Nyhan syndrome
0.000 0.988 0.012
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.988 0.012
I34 Nonrheumatic mitral valve disorders
0.000 0.988 0.012
I08.2 Disorders of both aortic and tricuspid valves
0.002 0.988 0.010
E88.3 Tumour lysis syndrome
0.000 0.988 0.011
I45.9 Conduction disorder, unspecified
0.000 0.989 0.011
I47.2 Ventricular tachycardia
0.000 0.989 0.011
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.989 0.011
I45.0 Right fascicular block
0.000 0.989 0.011
I45.4 Nonspecific intraventricular block
0.000 0.989 0.011
E85 Amyloidosis
0.000 0.989 0.010
I72 Other aneurysm
0.000 0.989 0.011
I95 Hypotension
0.000 0.990 0.010
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.990 0.010
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.990 0.010
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.990 0.010
E74.2 Disorders of galactose metabolism
0.000 0.990 0.010
E74.1 Disorders of fructose metabolism
0.000 0.990 0.010
E74.0 Glycogen storage disease
0.000 0.990 0.010
Z95.0 Presence of cardiac pacemaker
0.000 0.990 0.010
I77.5 Necrosis of artery
0.000 0.990 0.010
I77.4 Coeliac artery compression syndrome
0.000 0.990 0.010
I77.3 Arterial fibromuscular dysplasia
0.000 0.990 0.010
I45.8 Other specified conduction disorders
0.000 0.990 0.010
E73.8 Other lactose intolerance
0.000 0.990 0.009
E73.1 Secondary lactase deficiency
0.000 0.990 0.009
E73.0 Congenital lactase deficiency
0.000 0.990 0.009
I12.0 Hypertensive renal disease with renal failure
0.000 0.990 0.010
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.990 0.009
I45.3 Trifascicular block
0.000 0.990 0.009
I72.8 Aneurysm of other specified arteries
0.000 0.990 0.009
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.990 0.009
I45.6 Preexcitation syndrome
0.000 0.991 0.009
I45.5 Other specified heart block
0.000 0.991 0.009
I77.6 Arteritis, unspecified
0.000 0.991 0.009
I77.0 Arteriovenous fistula, acquired
0.000 0.991 0.009
I65.2 Occlusion and stenosis of carotid artery
0.000 0.991 0.009
I60-I69 Cerebrovascular diseases
0.000 0.991 0.009
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.991 0.009
I77.8 Other specified disorders of arteries and arterioles
0.000 0.991 0.009
J06.9 Acute upper respiratory infection, unspecified
0.000 0.991 0.009
I95.0 Idiopathic hypotension
0.000 0.992 0.008
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.992 0.008
I74 Arterial embolism and thrombosis
0.000 0.992 0.008
I72.0 Aneurysm of carotid artery
0.000 0.992 0.008
I72.9 Aneurysm of unspecified site
0.000 0.992 0.008
E85.8 Other amyloidosis
0.000 0.992 0.008
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.992 0.008
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.992 0.008
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.992 0.008
I72.4 Aneurysm of artery of lower extremity
0.000 0.992 0.008
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.992 0.008
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.992 0.008
I72.1 Aneurysm of artery of upper extremity
0.000 0.992 0.008
I70 Atherosclerosis
0.000 0.992 0.008
I51.8 Other ill-defined heart diseases
0.000 0.992 0.008
K86.0 Alcohol-induced chronic pancreatitis
0.006 0.992 0.002
I77.2 Rupture of artery
0.000 0.992 0.007
I72.2 Aneurysm of renal artery
0.000 0.992 0.008
I45.2 Bifascicular block
0.000 0.992 0.007
I95.8 Other hypotension
0.000 0.993 0.007
I61 Intracerebral haemorrhage
0.000 0.993 0.007
E85.3 Secondary systemic amyloidosis
0.000 0.993 0.007
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.993 0.007
I79.1 Aortitis in diseases classified elsewhere
0.000 0.993 0.007
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.993 0.007
K86.1 Other chronic pancreatitis
0.006 0.993 0.001
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.993 0.007
I74.5 Embolism and thrombosis of iliac artery
0.000 0.993 0.007
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.993 0.007
E80.5 Crigler-Najjar syndrome
0.000 0.993 0.007
E80.3 Defects of catalase and peroxydase
0.000 0.993 0.007
E80.0 Hereditary erythropoietic porphyria
0.000 0.993 0.007
I12.9 Hypertensive renal disease without renal failure
0.000 0.993 0.007
E89.0 Postprocedural hypothyroidism
0.000 0.993 0.007
Z90.4 Acquired absence of other parts of digestive tract
0.007 0.993 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.993 0.007
G20 Parkinson's disease
0.000 0.993 0.007
K66 Other disorders of peritoneum
0.006 0.993 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.993 0.006
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.993 0.006
I65.1 Occlusion and stenosis of basilar artery
0.000 0.993 0.006
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.993 0.006
I95.2 Hypotension due to drugs
0.000 0.993 0.007
E80.2 Other porphyria
0.000 0.993 0.006
E85.4 Organ-limited amyloidosis
0.000 0.993 0.006
I47.1 Supraventricular tachycardia
0.000 0.993 0.007
E80.1 Porphyria cutanea tarda
0.000 0.994 0.006
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.994 0.006
E80.6 Other disorders of bilirubin metabolism
0.000 0.994 0.006
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.994 0.006
K86.3 Pseudocyst of pancreas
0.004 0.994 0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.994 0.006
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.994 0.006
Z95.1 Presence of aortocoronary bypass graft
0.000 0.994 0.006
I62 Other nontraumatic intracranial haemorrhage
0.000 0.994 0.006
K86.2 Cyst of pancreas
0.004 0.994 0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.994 0.006
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.994 0.006
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.994 0.006
H73.8 Other specified disorders of tympanic membrane
0.006 0.994 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.994 0.006
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.994 0.006
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.994 0.006
E73.9 Lactose intolerance, unspecified
0.001 0.994 0.005
I70.0 Atherosclerosis of aorta
0.000 0.994 0.006
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.994 0.006
I70.9 Generalised and unspecified atherosclerosis
0.000 0.994 0.006
I70.8 Atherosclerosis of other arteries
0.000 0.994 0.006
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.994 0.006
S02.00 Fracture of vault of skull (closed)
0.006 0.994 0.000
E85.9 Amyloidosis, unspecified
0.001 0.994 0.005
I34.1 Mitral (valve) prolapse
0.000 0.994 0.006
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.994 0.006
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.994 0.006
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.005 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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